https://cassyni.com/slides/outline/GGca8u5gtyyxs1eUnnx5yw https://cassyni.com/events/GGca8u5gtyyxs1eUnnx5yw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Qr8LoSsP7NYeRfo4yjBsWN https://cassyni.com/events/GGca8u5gtyyxs1eUnnx5yw?videoPreview=1 Does a Digital Twin have a Digital Twin?nohttps://cassyni.com/events/GGca8u5gtyyxs1eUnnx5yw?videoPreview=12021-09-08T10:00:00+00:003989.6Data-Centric Engineering JournalSince the early days of what is known today as the Internet of Things, there have been over twenty years of research. Such systems are key sources of the data that feed Digital Twins; indeed this might even be in real-time. However, when one talks to real users in the worlds of civil engineering, environment modelling, digital agriculture and the industrial IoT etc. they complain about IoT systems being flaky and completely unusable after a few years. Given that these users are designing infrastructures that are required to last potentially 10 to hundreds of years what are the implications for the field of IoT if we cannot deliver? In my talk I will discuss some of the issues we have been dealing with and put forward some of my thoughts of what we need to start looking at, as a community. Real users of networked sensor systems want smart infrastructures, my question is, will Digital Twin driven systems thinking be the answer?https://cassyni-user-files-prod.s3.amazonaws.com/Qr8LoSsP7NYeRfo4yjBsWN https://cassyni.com/slides/outline/9N1hS2nQbhyuFn1fdysAaq https://cassyni.com/events/9N1hS2nQbhyuFn1fdysAaq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/SxMSBEp2AUMLL38viSzXjC https://cassyni.com/events/9N1hS2nQbhyuFn1fdysAaq?videoPreview=1 Total variation minimization on graphs for semisupervised and unsupervised machine learningnohttps://cassyni.com/events/9N1hS2nQbhyuFn1fdysAaq?videoPreview=12021-01-08T14:00:00+00:004542.04AI Institute in Dynamic SystemsTotal variation (TV) minimization has made a big impact in image processing for applications such as denoising, deblurring, and segmentation. The TV functional has a geometric meaning in Euclidean space related to the constraints on perimeter of regions. In a graphical setting we can define the graph TV functional and connect it to the graph min cut problem. This allows us to develop methods for machine learning involving similarity graphs for high dimensional data. I will talk about semi-supervised learning, unsupervised learning, and a the connection to modularity optimization for community detection on networks. I will intruce a graph version of the Ginzburg-Landau energy and discuss its gamma convergence to graph TV. This will motivate the development of fast methods with dynamic thresholding for solving penalized graph cut.https://cassyni-user-files-prod.s3.amazonaws.com/SxMSBEp2AUMLL38viSzXjC https://cassyni.com/events/RenwSjoEDsst3Pd6orUV9w/seminar/qa https://cassyni.com/slides/outline/RenwSjoEDsst3Pd6orUV9w https://cassyni.com/events/RenwSjoEDsst3Pd6orUV9w/abstract https://cassyni-user-files-prod.s3.amazonaws.com/MKuUNe2h5nXWYdwmMzagJJ https://cassyni.com/events/RenwSjoEDsst3Pd6orUV9w?videoPreview=1 Flutter Control via Data-Driven Modelsnohttps://cassyni.com/events/RenwSjoEDsst3Pd6orUV9w?videoPreview=12023-11-15T15:00:00+00:002251.2Nonlinear Dynamics, an International Journal of Nonlinear Dynamics and Chaos in Engineering SystemsActive flutter suppression is a promising technology for advanced flight vehicles, but greatly relies on accurate and simple models of fluid-structure interaction. For example, it is a great challenge to establish such a model for the flutter controller of an aircraft subject to a transonic flow, which is nonlinear by nature. The lecture addresses how to construct a surrogate model from CFD data to predict the transonic flutter of an aircraft wing and to actively suppress it in a wide range of flow regime. The lecture presents how to use simple physical knowledge to improve both interpretability and generalizability of the surrogate model, which are two essential issues in data-driven modeling. The lecture also shows the design of a flutter controller via machine learning.https://cassyni-user-files-prod.s3.amazonaws.com/MKuUNe2h5nXWYdwmMzagJJ https://cassyni.com/events/3vGMQfL8ujWUEeLpRm5pTX/seminar/qa https://cassyni.com/slides/outline/3vGMQfL8ujWUEeLpRm5pTX https://cassyni.com/events/3vGMQfL8ujWUEeLpRm5pTX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PYzGwkEZy8g9XRnf4wsx94 https://cassyni.com/events/3vGMQfL8ujWUEeLpRm5pTX?videoPreview=1 Presentation of the book "Logic - Language - Ontology"nohttps://cassyni.com/events/3vGMQfL8ujWUEeLpRm5pTX?videoPreview=12023-03-29T14:00:00+00:005321.24Logica UniversalisHow should we think about the meaning of the words that make up our language? How does reference of these terms work, and what is their referent when these are connected to abstract objects rather than to concrete ones? Can logic help to address these questions? This collection of papers aims to unify the questions of syntax and semantics of language, which span across the fields of logic, philosophy and ontology of language. The leading motif of the presented selection is the differentiation between linguistic tokens (material, concrete objects) on the one hand and linguistic types (ideal, abstract objects) on the other. Through a promenade among articles that span over all of the Author’s career, this book addresses the complex philosophical question of the ontology of language by following the crystalline conceptual tools offered by logic. At the core of Wybraniec-Skardowska’s scholarship is the idea that language is an ontological being, characterized in compliance with the logical conception of language proposed by Ajdukiewicz. The application throughout the book of tools of classical logic and set theory results fosters the emergence of a general formal logical theory of syntax, semantics and of the pragmatics of language, which takes into account the duality token-type in the understanding of linguistic expressions. Via a functional approach to language itself, logic appears as ontologically neutral with respect to existential assumptions relating to the nature of linguistic expressions and their extra-linguistic counterparts.https://cassyni-user-files-prod.s3.amazonaws.com/PYzGwkEZy8g9XRnf4wsx94 https://cassyni.com/events/GGUTZkWFtBML8KadQ7eYbf/seminar/qa https://cassyni.com/slides/outline/GGUTZkWFtBML8KadQ7eYbf https://cassyni.com/events/GGUTZkWFtBML8KadQ7eYbf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GkruFCeTYyis4EtuBy2Uwp https://cassyni.com/events/GGUTZkWFtBML8KadQ7eYbf?videoPreview=1 Micro and nanobubbles in membrane processes: State-of-the-art and the way forwardnohttps://cassyni.com/events/GGUTZkWFtBML8KadQ7eYbf?videoPreview=12023-04-17T11:00:00+00:003961.88ElsevierAir-water micro nanobubbles MNBs can be produced by four different methods and be used to improve: Oxygen transfer in microbiological processes with a high consumption rate Algae flotation Decomposition of organic compounds Fouling mitigation in membranes The macrobubbles and slugs are currently implemented in the industry, and MNBs are investigated in the labs. The webinar maps ways to explore the full potential of MNB flows through basic definitions, state-of-the-art analytical techniques, bubble generation methods, and the implementation of engineering principles in water and wastewater treatment processes. The future of air-water flows is in the intentional integration of MNBs in industrial processes alongside macrobubbles and air slugs. The most significant promise held by MNBs is in a continuous depreciation of the role water treatment chemicals play in water treatment processes. A deliberate generation of OH· radicals for the inactivation of pathogens and oxidation of micropollutants may start the movement away from chemical inactivation towards more sustainable water resources. Mitigation of membrane fouling without strong inorganic oxidants will prolong the life of polymer membranes. Better collision and adhesion of MNBs and higher lift of macrobubbles can significantly increase the efficiency of algae flotation, reduce flocculants, and adjust the process for the physical removal of micropollutants. Higher oxygen transfer rates can improve microbiological treatment and lower the necessity and load of further treatment stages. https://cassyni-user-files-prod.s3.amazonaws.com/GkruFCeTYyis4EtuBy2Uwp https://cassyni.com/events/V7Mnt9qnhSgHtnPHfBgcbf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/REkoTtjnAscyKa2933QkYN https://cassyni.com/slides/outline/PgCXG1D8U3f7wgLsStcYjP https://cassyni.com/events/PgCXG1D8U3f7wgLsStcYjP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/P1bWcGEVqtSBxkAZ7f8QS2 https://cassyni.com/events/PgCXG1D8U3f7wgLsStcYjP?videoPreview=1 Sparse Nonlinear Models for Fluid Dynamics with Machine Learning and Optimizationnohttps://cassyni.com/events/PgCXG1D8U3f7wgLsStcYjP?videoPreview=12022-02-11T12:00:00+00:002307.52Brunton LabReduced-order models of fluid flows are essential for real-time control, prediction, and optimization of engineering systems that involve a working fluid. The sparse identification of nonlinear dynamics (SINDy) algorithm is being used to develop nonlinear models for complex fluid flows that balance accuracy and efficiency. We explore recent innovations related to several complex flow fields: bluff body wakes, cavity flows, thermal and electro convection, and magnetohydrodynamics.https://cassyni-user-files-prod.s3.amazonaws.com/P1bWcGEVqtSBxkAZ7f8QS2 https://cassyni.com/slides/outline/LDfHwDgTPqnUuz3JoEEbCZ https://cassyni.com/events/LDfHwDgTPqnUuz3JoEEbCZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/SLU8cYaLZEWBgS73KTVaFG https://cassyni.com/events/LDfHwDgTPqnUuz3JoEEbCZ?videoPreview=1 Overview of Deep Reinforcement Learning Methodsnohttps://cassyni.com/events/LDfHwDgTPqnUuz3JoEEbCZ?videoPreview=12022-01-21T12:00:00+00:001489.44Brunton LabThis video gives an overview of methods for deep reinforcement learning, including deep Q-learning, actor-critic methods, deep policy networks, and policy gradient optimization algorithms.https://cassyni-user-files-prod.s3.amazonaws.com/SLU8cYaLZEWBgS73KTVaFG https://cassyni.com/slides/outline/T2LBF6WiSjyshsFt5BBjb https://cassyni.com/events/T2LBF6WiSjyshsFt5BBjb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Vvb6uwkBnDQo1tt3QWvWmU https://cassyni.com/events/T2LBF6WiSjyshsFt5BBjb?videoPreview=1 Science and Engineering of Robotics and Biorobotics: From Vision to Realitynohttps://cassyni.com/events/T2LBF6WiSjyshsFt5BBjb?videoPreview=12023-03-31T03:00:00+00:004054.88Mechanical EngineeringRobotics is a multidisciplinary discipline which belongs to both science and engineering. In science, it contributes discovering and explaining phenomena and natural systems; this is the case of biorobotics, investigating biological systems and building biomimetic robots. In engineering, robotics responds to the needs of a diversity of application fields, from medicine to industry. This talk is going to illustrate how robotics evolved from the technologies for industrial manufacturing to current service robots, and from the foundational research in bionic components and bioinspired systems to current scenarios of robot companions and industry 5.0. https://cassyni-user-files-prod.s3.amazonaws.com/Vvb6uwkBnDQo1tt3QWvWmU https://cassyni.com/slides/outline/BKzR6v31VbpJjDsHPdwYsX https://cassyni.com/events/BKzR6v31VbpJjDsHPdwYsX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/1TUntEsnRCQokx8wgEyrn https://cassyni.com/events/BKzR6v31VbpJjDsHPdwYsX?videoPreview=1 Plasmon-enhanced Pathogen Inactivation: Shockwaves as selective anti-microbialsnohttps://cassyni.com/events/BKzR6v31VbpJjDsHPdwYsX?videoPreview=12022-09-22T09:00:00+00:003725.12Journal of Biological PhysicsCan Physical fields be tailored on nanoscale to eliminate viral contamination of bioreactors? Given that Bioreactors are crucial for producing 21st century antibody pharmaceuticals, the need is for selective inactivation of pathogens without collateral damage to precious macromolecules. Our collaborative experiments suggest that plasmonically enhanced shockwaves generated by ultrafast lasers in designed nanoparticle systems can indeed safely inactivate viruses in bioreactors without the need for targeting. What are the prospects for ‘shockceuticals’ and Physics-based approaches for 21st century applications of Biological Physics? https://cassyni-user-files-prod.s3.amazonaws.com/1TUntEsnRCQokx8wgEyrn https://cassyni.com/events/MhdjBu8v7aNTQCrphJptBf/seminar/qa https://cassyni.com/slides/outline/MhdjBu8v7aNTQCrphJptBf https://cassyni.com/events/MhdjBu8v7aNTQCrphJptBf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LbtBkSK6x5E4ZFNh74Wrfg https://cassyni.com/events/MhdjBu8v7aNTQCrphJptBf?videoPreview=1 Epitaxial Nitride Thin Films and Heterostructures: Emerging Applications and Future Prospectsnohttps://cassyni.com/events/MhdjBu8v7aNTQCrphJptBf?videoPreview=12023-05-12T08:00:00+00:003867.6School of Chemical and Physical SciencesNitride thin films and heterostructures have been at the forefront of innovation and discovery for decades. While GaN remains one of the most famous nitride semiconductors, recent years have seen the rise of several transition metal and rare-earth nitride semiconductors, metals, and their heterostructures. In this talk, I will present our research on epitaxial nitride thin film semiconductors and metal/semiconductor superlattices for various nanophotonic, neuromorphic computing, and phase-change material applications.https://cassyni-user-files-prod.s3.amazonaws.com/LbtBkSK6x5E4ZFNh74Wrfg https://cassyni.com/events/6tBboPjAwqkq6Ga7gf19dw/seminar/qa https://cassyni.com/slides/outline/6tBboPjAwqkq6Ga7gf19dw https://cassyni.com/events/6tBboPjAwqkq6Ga7gf19dw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Lc3fjJaFXGx9kZ7Jr4jNvA https://cassyni.com/events/6tBboPjAwqkq6Ga7gf19dw?videoPreview=1 Numerics for CFDnohttps://cassyni.com/events/6tBboPjAwqkq6Ga7gf19dw?videoPreview=12023-06-15T08:00:00+00:005514.56NEKTAR++Parallel-in-time algorithms are more and more recognized as a promising solution to increase computational concurrency after the maximum speed-up has been achieved from spatial parallelism due to communication overhead when the problem size per processor has become too small in distributed memory high-performance computing architecture. Two popular time-parallel approaches are the Parareal algorithm, first introduced by Lions et al. (2001), and the Parallel Full Approximation Scheme in Space and Time (PFASST) technique of Emmett and Minion (2012). Both methods are based on the use of multi-level time-integration, exploiting a fine and a coarse time integrators in combination with an iterative procedure to achieve parallelism in time. The implementation of these two parallel-in-time algorithms in the Nektar++ spectral/hp element framework is described. The extension of the MPI topology to allow concurrency in time is first presented. Following, the implementation of new drivers for the Parareal and PFASST algorithms is described. Finally, application examples for the 1D advection and the 2D diffusion equations are demonstrated. The least-squares finite element method (LSFEM) emerged as an alternative to classical Galerkin FEM around 30 years ago. Since then, it has successfully found applications in many fields of computational physics, including fluid dynamics. The method possesses some desirable properties – it always leads to symmetric, positive-definite algebraic systems (even for non-self-adjoint operators), it does not necessitate the fulfillment of compatibility (LBB) conditions, and it is generally more stable than its classical counterpart. Conversely, it requires recasting equations to the first order (introducing additional degrees of freedom) and involves a more computationally expensive assembly procedure. This talk will attempt to evaluate whether the benefits of LSFEM outweigh its drawbacks and offer a practical perspective on how it can be employed to efficiently solve incompressible flow problems. We will show an alternative equation splitting scheme, which, in conjunction with LSFEM, leads to an enhanced convergence rate. Finally, we will discuss computational aspects of the method using the author’s high-order code L3STER as a point of reference. In particular, we will show how to structure assembly so that it fully utilizes CPU caches, and how hybrid parallelism can be leveraged for improved scalability.https://cassyni-user-files-prod.s3.amazonaws.com/Lc3fjJaFXGx9kZ7Jr4jNvA https://cassyni.com/events/7NqCr5NhPJJt6371H6HwuF/seminar/qa https://cassyni.com/slides/outline/7NqCr5NhPJJt6371H6HwuF https://cassyni.com/events/7NqCr5NhPJJt6371H6HwuF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5R7d6os46nF9kzZKi3HNT8 https://cassyni.com/events/7NqCr5NhPJJt6371H6HwuF?videoPreview=1 Quantum simulation of ODEs, PDEs and related problems. Part II: Nonlinear problems and applicationsnohttps://cassyni.com/events/7NqCr5NhPJJt6371H6HwuF?videoPreview=12023-11-13T15:00:00+00:004224.08Journal of Computational PhysicsIn the second part of the lectures on quantum simulation for partial differential equations, we will focus on nonlinear partial differential equations and applications of Schrodingerisation. 1) For (nonlinear) Hamilton-Jacobi equation and scalar nonlinear hyperbolic equations, we use the level set method to map them exactly to phase space linear transport PDEs so they can be implemented with quantum algorithms. We gain quantum advantage for various physical and numerical parameters. 2) We show how to apply Schrodingerisation to a system of (nonlinear) ordinary differential equations. 3) For (both artificial and physical) boundary value and interface problems of linear PDEs, we show how one can Schrodingerise them so they become suitable for quantum simulations. 4) We give an example of Schrodingerisation for Maxwell’s equations.https://cassyni-user-files-prod.s3.amazonaws.com/5R7d6os46nF9kzZKi3HNT8 https://cassyni.com/events/EHufVeS3Xi4far6aeXrt3w/seminar/qa https://cassyni.com/slides/outline/EHufVeS3Xi4far6aeXrt3w https://cassyni.com/events/EHufVeS3Xi4far6aeXrt3w/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Vo7myyWuVC8hHHU3MLYSer https://cassyni.com/events/EHufVeS3Xi4far6aeXrt3w?videoPreview=1 Session 2: Real-world examples in trial protocols and trial reports (for Clinical Trialists and Methodologists)nohttps://cassyni.com/events/EHufVeS3Xi4far6aeXrt3w?videoPreview=12023-07-14T10:30:00+00:001984.0Institute for Cancer ResearchNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/Vo7myyWuVC8hHHU3MLYSer https://cassyni.com/slides/outline/QAuNXwtRiE4ib9NrQWB23f https://cassyni.com/events/QAuNXwtRiE4ib9NrQWB23f/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Jtg1CMBVTce3TvK5KnvQvA https://cassyni.com/events/QAuNXwtRiE4ib9NrQWB23f?videoPreview=1 Fixed-point theory and Green’s functions for the solution of DEs: An iterative strategynohttps://cassyni.com/events/QAuNXwtRiE4ib9NrQWB23f?videoPreview=12023-07-27T16:00:00+00:003201.76Journal of Mathematical SciencesA recently developed iterative method for estimating the solution of ordinary and fractional boundary-value problems is described. The strategy is based on the construction of a tailored integral operator described in terms of the Green's function, which corresponds to the highest order linear derivative term. After then, the integral operator is subjected to a fixed-point scheme like Picard's, Mann's, or Ishikawa's. The convergence of the scheme is assessed. Numerical tests are used to assess the applicability and correctness of the approach.https://cassyni-user-files-prod.s3.amazonaws.com/Jtg1CMBVTce3TvK5KnvQvA https://cassyni.com/slides/outline/KERL57RBKeXhC3fWQ2U2KX https://cassyni.com/events/KERL57RBKeXhC3fWQ2U2KX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DVShpxpnfb3WKH4oMa7Yk6 https://cassyni.com/events/KERL57RBKeXhC3fWQ2U2KX?videoPreview=1 Mechanisms for peer review and grant-awardingnohttps://cassyni.com/events/KERL57RBKeXhC3fWQ2U2KX?videoPreview=12023-04-17T17:00:00+00:003557.08DeSci FoundationIn this seminar, Davide covered questions like: How do we decide who gets to review which proposals? How do we best evaluate the work they do? And how do we aggregate and align the (often conflicting) reviews from multiple reviewers?https://cassyni-user-files-prod.s3.amazonaws.com/DVShpxpnfb3WKH4oMa7Yk6 https://cassyni.com/slides/outline/S9VnigUXU4HUgrf5mU2xUD https://cassyni.com/events/S9VnigUXU4HUgrf5mU2xUD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EX6D9tgUjLU2kQuABDePsk https://cassyni.com/slides/outline/Vc323U1CYGA7iYxeR8Qv13 https://cassyni.com/events/Vc323U1CYGA7iYxeR8Qv13/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XPyUsNYSyo2n5e6yqqXuvW https://cassyni.com/events/Vc323U1CYGA7iYxeR8Qv13?videoPreview=1 How to Convert a Nano-powder into a Nano-crystalline Solidnohttps://cassyni.com/events/Vc323U1CYGA7iYxeR8Qv13?videoPreview=12020-09-22T12:00:00+00:003037.2Granular MatterLargely unnoticed by theoretical physics, the last 20 years have seen a revolution in nano-particle processing. One example is that powders - although very porous, when freshly produced - can be converted into a dense solid, which still keeps a microstructure at the nanoscale. The processes are new developments related to what traditionally was called "Spark Plasma Sintering", but has nothing to do with sparks and plasmas. Computer simulations predict intermediate steps of these processes and reveal the underlying mechanisms. I will give a review of recent simulations, with a focus on so-called flash-sintering.https://cassyni-user-files-prod.s3.amazonaws.com/XPyUsNYSyo2n5e6yqqXuvW https://cassyni.com/events/Ucjox6i9fM3y3o8eK9wbC9/seminar/qa https://cassyni.com/slides/outline/Ucjox6i9fM3y3o8eK9wbC9 https://cassyni.com/events/Ucjox6i9fM3y3o8eK9wbC9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8g1kTpPPsCpWeCp1xDrmcz https://cassyni.com/events/Ucjox6i9fM3y3o8eK9wbC9?videoPreview=1 Observing Open Access Weeknohttps://cassyni.com/events/Ucjox6i9fM3y3o8eK9wbC9?videoPreview=12023-10-25T08:00:00+00:002068.72Topics at the heart of our communityIn recognition of International Open Access Week 2023, we will explore the transformative power and dynamic landscape of open access publishing. OA supports the greater visibility and impact of your work by ensuring reach to a broad and diverse global readership, transcending traditional barriers. OA is also a space where innovative formats and approaches are encouraged, which fosters creativity and experimentation in how research is communicated. Our presenters will showcase the depth and breadth of OA publishing at Springer Nature and how we are at the forefront driving open research and championing open science.https://cassyni-user-files-prod.s3.amazonaws.com/8g1kTpPPsCpWeCp1xDrmcz https://cassyni.com/slides/outline/5QGQmyJV2q2DYsCoVM7cah https://cassyni.com/events/5QGQmyJV2q2DYsCoVM7cah/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8w5XBEG82dArfT6AriZEpv https://cassyni.com/events/5QGQmyJV2q2DYsCoVM7cah?videoPreview=1 Adversarial Machine Learningnohttps://cassyni.com/events/5QGQmyJV2q2DYsCoVM7cah?videoPreview=12022-07-21T12:30:00+00:003290.8Journal on Image and Video ProcessingMachine-learning algorithms are widely used for cybersecurity applications, including spam, malware detection, biometric recognition. In these applications, the learning algorithm must face intelligent and adaptive attackers who can carefully manipulate data to purposely subvert the learning process. As machine learning algorithms have not been originally designed under such premises, they have been shown to be vulnerable towell-crafted attacks, including test-time evasion and training-time poisoning attacks (also known as adversarial examples). This talk aims to introduce the fundamentals of adversarial machine learning and some techniques to assess the vulnerability of machine-learning algorithms to adversarial attacks. We report application examples including object recognition in images, biometric identity recognition, spam, and malware detection.https://cassyni-user-files-prod.s3.amazonaws.com/8w5XBEG82dArfT6AriZEpv https://cassyni.com/slides/outline/4QyCgc1S9uv4t7NoPNeHmo https://cassyni.com/events/4QyCgc1S9uv4t7NoPNeHmo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DT4nUmkG5PoVoDCGfyRpyL https://cassyni.com/events/4QyCgc1S9uv4t7NoPNeHmo?videoPreview=1 (Predicting) Replication Outcomesnohttps://cassyni.com/events/4QyCgc1S9uv4t7NoPNeHmo?videoPreview=12023-11-20T16:00:00+00:003520.12DeSci FoundationWhat share of results replicate in different literatures in some of the experimental social sciences? I will discuss several large replication projects in psychology and economics, where my coauthors and I have redone experiments published in high-impact journals with new and larger samples to see whether the main result replicates. The seminar will also cover our studies on forecasting prediction markets and surveys where researchers attempt to predict replication outcomes and outcomes of new hypothesis tests. I will also talk about recent work on multi-analyst projects and conceptual replications where we either ask researchers to test the same hypotheses on the same data or design different experiments testing the same hypothesis.https://cassyni-user-files-prod.s3.amazonaws.com/DT4nUmkG5PoVoDCGfyRpyL https://cassyni.com/events/FHEVheEyoz6YQPCpzusyid/seminar/qa https://cassyni.com/slides/outline/FHEVheEyoz6YQPCpzusyid https://cassyni.com/events/FHEVheEyoz6YQPCpzusyid/abstract https://cassyni-user-files-prod.s3.amazonaws.com/92aDpCDUAeHyxei6aVsaY6 https://cassyni.com/events/FHEVheEyoz6YQPCpzusyid?videoPreview=1 Nature Water Talks: Water and Foodnohttps://cassyni.com/events/FHEVheEyoz6YQPCpzusyid?videoPreview=12023-10-16T16:00:00+00:003440.28Nature WaterThe theme for the 2023 World food day is about the connection between water and food. An essential connection especially considering that the vast majority of freshwater resources are used for agriculture. We shall discuss with Sera Young (Northwestern University), Kyle Davis (University of Delaware) and Pablo Gaitán-Rossi (Universidad Iberoamericana) about how we can assess and monitor water and food insecurities, and we what are the paths that can be taken to improve access to these essential resources. This event is also streamed by the Hydro90 Bilibili channel https://space.bilibili.com/662336752/ https://cassyni-user-files-prod.s3.amazonaws.com/92aDpCDUAeHyxei6aVsaY6 https://cassyni.com/events/9r6rC88Cyx1U1WxbPztBjB/seminar/qa https://cassyni.com/slides/outline/9r6rC88Cyx1U1WxbPztBjB https://cassyni.com/events/9r6rC88Cyx1U1WxbPztBjB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/J7xVVnpincD7AjkkucF5c2 https://cassyni.com/events/9r6rC88Cyx1U1WxbPztBjB?videoPreview=1 Chaos in confinement: How to make shear-thinning fluids flow thickennohttps://cassyni.com/events/9r6rC88Cyx1U1WxbPztBjB?videoPreview=12023-11-03T16:00:00+00:004016.52Journal of Fluid MechanicsMany energy, environmental, industrial, and microfluidic processes rely on the viscous flow of polymer solutions through confined and tortuous spaces. These fluids are typically shear-thinning; however, unexpectedly, these solutions can flow thicken - that is, the macroscopic flow resistance abruptly increases above a threshold flow rate - but only in a confined, tortuous space, not in bulk solution. The reason why has been a puzzle for over half a century. In this talk, I will describe how by directly visualizing the flow in a transparent 3D porous medium, we have shown that this anomalous flow thickening reflects the onset of an elastic instability in which the fluid exhibits chaotic spatiotemporal velocity fluctuations reminiscent of inertial turbulence, despite the vanishingly small Reynolds number. Our measurements help characterize the onset and characteristics of this fascinating flow state, helping to deepen understanding of complex fluid flows in confinement and providing guidelines for predicting and controlling these flows in applications. Indeed, I will describe how, to this end, we have shown that this phenomenon can be harnessed for improving fluid and solute homogenization and mixing, and thereby the efficiency of flow-mediated chemical reactions, in porous media - with implications for a broad range of environmental and industrial processes that are typically limited by poor mixing.https://cassyni-user-files-prod.s3.amazonaws.com/J7xVVnpincD7AjkkucF5c2 https://cassyni.com/events/NCLaTqpDMkn43ftoevPMVw/seminar/qa https://cassyni.com/slides/outline/NCLaTqpDMkn43ftoevPMVw https://cassyni.com/events/NCLaTqpDMkn43ftoevPMVw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4uabSUfhpEDdVRpEFMmvoY https://cassyni.com/events/NCLaTqpDMkn43ftoevPMVw?videoPreview=1 A Universal Infrastructure for Learning Languages through Cultural Activities: The ENACT Web Appnohttps://cassyni.com/events/NCLaTqpDMkn43ftoevPMVw?videoPreview=12023-11-21T23:10:00+00:003472.2Linguistics and Applied Language Studies[ENACT](https://enacteuropa.com/) is a free web app developed at Newcastle University UK, co-funded by the European Union. The app enables people to learn aspects of foreign languages while performing a meaningful real-world task which enables them to experience the culture of the foreign language. Users can learn a foreign language through the foreign culture by carrying out a cultural activity. Learn Māori while you’re making a poi ball! Devices will guide users through the stages of doing the activity through structured interactive content using photos, text, audio and video to help them. People can use the ENACT Author to create their own favourite cultural activity in their own language so that anyone else round the world can use it to learn the language and culture. ENACT has been used by over 11,000 people in 153 countries. In this presentation, I will provide an overview of the project aims, introduce the task-based language teaching and online interactive material design principles underlying the app design, and briefly demonstrate the key features of the ENACT app: the interactive player, the author, and the community. I will discuss my experience of collecting Māori materials during my last trip to NZ in 2022 show those materials. I will also update on our latest materials for learning Chinese. During the Q&A, we can explore opportunities for producing materials for other cultures and languages. https://cassyni-user-files-prod.s3.amazonaws.com/4uabSUfhpEDdVRpEFMmvoY https://cassyni.com/events/QfabhG3qZ3YYQcNNCcHzDs/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8dP3RbmZv1s1xA3dWJ4LUn https://cassyni.com/events/2SQQcVwDoSdQLdtkdnrdE5/seminar/qa https://cassyni.com/slides/outline/2SQQcVwDoSdQLdtkdnrdE5 https://cassyni.com/events/2SQQcVwDoSdQLdtkdnrdE5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/38n9uQ9susS1Ji6AaEbAkW https://cassyni.com/events/2SQQcVwDoSdQLdtkdnrdE5?videoPreview=1 Large-scale DFT calculations for materials with complex structuresnohttps://cassyni.com/events/2SQQcVwDoSdQLdtkdnrdE5?videoPreview=12024-02-12T14:00:00+00:003540.24Computer Physics CommunicationsUtilizing the interaction between nanoscale systems is important to create new material functionality. First-principles density functional theory (DFT) calculation is a powerful tool to investigate the correlation between the atomic and electronic structures which cause materials properties. To describe complex nanoscale structures such as interfaces, defect complexes and disordered systems, large-scale structural models consisting of several thousands of atoms or more are required. However, conventional DFT calculations are limited to be typically less than a thousand atoms because the computational cost scales cubically to the number of atoms N. To overcome the limitation, we have developed a large-scale DFT code CONQUEST [1,2]. CONQUEST can treat large systems by using local orbitals to express density matrices and a linear-scaling (O(N)) method based on the density matrix minimization. The computational cost scales cubically to the number of the support functions, both in the O(N) and the conventional diagonalization calculations. Therefore, to reduce the number of support functions without losing accuracy, we have introduced multi-site support functions (MSSF) [3,4]. MSSFs are the linear combinations of pseudo-atomic orbitals from a target atom and its neighbor atoms in a cutoff region. MSSFs correspond to local molecular orbitals so that the number of required support functions can be the minimal. We have also proposed an efficient and comprehensive method to find out the atoms with characteristic electronic structures in large-scale systems by using statistical methods. We have investigated supported metallic nanoparticles in which the interaction between the nanoparticle and the support base plays an important role for catalytic reactivity. By our large-scale DFT calculation and the statistical analysis, the size- and site-dependence of atomic and electronic structures have been investigated for isolated and supported nanoparticles. https://cassyni-user-files-prod.s3.amazonaws.com/38n9uQ9susS1Ji6AaEbAkW https://cassyni.com/slides/outline/Kj6ZERabAU1X1Wf2C8azVj https://cassyni.com/events/Kj6ZERabAU1X1Wf2C8azVj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FcNgoxQbjtHxMfnYMVF1JN https://cassyni.com/events/Kj6ZERabAU1X1Wf2C8azVj?videoPreview=1 Introducing Transformative Plant Biotechnology: Engineering plants to recover metals from our environmentnohttps://cassyni.com/events/Kj6ZERabAU1X1Wf2C8azVj?videoPreview=12023-09-22T09:15:00+00:001705.76The New Phytologist FoundationGold nanoparticles (Au-NPs), synthesised through chemical processes, find extensive utility as catalysts in various industrial applications. Interestingly, plants have the natural ability to accumulate gold in the form of nanoparticles within their tissues when exposed to this element. This plant-derived material can be effectively utilised in the development of catalysts derived from biomass. Laboratory experiments have demonstrated that by introducing specific, short peptides (around 10 amino acids in length) into solutions, we can exert precise control over the size and shape of these nanoparticles. These factors can be finely tuned to optimise catalysts for various industrial processes. Introducing these peptides into the model plant species, Arabidopsis, allows us to regulate the diameter of nanoparticles within the plant itself, consequently influencing catalytic performance in the resulting pyrolysed biomass. Leveraging Au-rich biomass in this manner holds the potential to make economically viable the use of plants for remediating and stabilising mining waste, particularly those rich in precious elements like gold. Consequently, this study, using gold as an exemplar, represents a significant step towards engineering plants for the sustainable recovery of finite, technologically critical elements from our environment.https://cassyni-user-files-prod.s3.amazonaws.com/FcNgoxQbjtHxMfnYMVF1JN https://cassyni.com/slides/outline/T8pcvgHTkLKMW6BVA1Siuj https://cassyni.com/events/T8pcvgHTkLKMW6BVA1Siuj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Poqnev9tZi8fuYxvRKDWbQ https://cassyni.com/events/T8pcvgHTkLKMW6BVA1Siuj?videoPreview=1 DEIM Reduced Order Model Constructed by Hybrid Snapshot Simulationnohttps://cassyni.com/events/T8pcvgHTkLKMW6BVA1Siuj?videoPreview=12021-06-17T12:00:00+00:003658.28Discover Applied SciencesThis paper presents a methodology that combines the hybrid snapshot simulation (Bai and Wang in Int J Comput Methods 18:2050029, 2020) and the discrete empirical interpolation method (DEIM) to reduce the computational cost of constructing a DEIM-based nonlinear reduced order model (ROM) while preserving its accuracy. In distinct contrast to its traditional counterpart, the time span of the hybrid snapshot simulation is divided into multiple intervals, and a majority of the intervals are simulated by local ROMs, while a fraction by the full order model (FOM). To tackle the challenge associated with limited FOM data for ROM-DEIM construction, a new approach is proposed to reconstruct and enrich the snapshot data of nonlinear model terms using solution data in ROM intervals. A formulation and procedure based on the cell-centered finite volume method (FVM) scheme are also developed to take into account two types of nonlinearities in ROM-DEIM: the componentwise and the transport-related, non-componentwise. A global ROM-DEIM is produced immediately at the end of the snapshot simulation and can be used to accelerate online simulation for different scenarios. The proposed methodology demonstrates excellent computational performance. Specifically, the computational time of the snapshot simulation is reduced by 50% without compromising ROM-DEIM accuracy (relative error less than 0.8% compared with FOM). The results prove feasibility of combining hybrid snapshot simulation and DEIM for robust and efficient ROM-DEIM development.https://cassyni-user-files-prod.s3.amazonaws.com/Poqnev9tZi8fuYxvRKDWbQ https://cassyni.com/events/CKNVYAsiabhjC9tn9MczN1/seminar/qa https://cassyni.com/slides/outline/CKNVYAsiabhjC9tn9MczN1 https://cassyni.com/events/CKNVYAsiabhjC9tn9MczN1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9h8XVwz7cgacbBCDyNKfxr https://cassyni.com/events/CKNVYAsiabhjC9tn9MczN1?videoPreview=1 Biosynthesis and Functions of the Nickel-Pincer Nucleotide (NPN) Cofactornohttps://cassyni.com/events/CKNVYAsiabhjC9tn9MczN1?videoPreview=12024-01-16T14:00:00+00:004121.6BioMetalsThis short presentation will be an introduction to the Biometals webinars series organized by the International Biometals society and the Biometals Journal. Biometal webinars will be monthly in 2024 jointly organized by the Cassiny platform, Springer and the International Biometals society. It will be with two speakers, one senior scientist one younger. One of them at least author of a recent Biometals article. confirmed senior speakers: January 16th, 2024:Bob Hausinger (Ni) ; February 13th, 2024: David Frazer (Fe) ; March 12th , 2024: Wolfgang Maret (Zn) ; April 9th 2024: Alison Butler (Fe) ; May 7th 2024: John Helmann (Fe) ; Free of access, each webinar will be live and accessible live on the Cassyni Platform followed by questions & and answers time. It will also be recorded and be accessible (if accepted by the speaker) on the platform. A DOI number will be assigned to the recorded presentation. This will not replace the face-to-face Biometals symposium that should be take place in summer 2025. The nickel-pincer nucleotide (NPN) cofactor catalyzes the proton-coupled hydride-transfer reactions of selected racemases and epimerases (1-2). This novel organometallic molecule has a square-planar nickel atom that is tri-coordinated by a modified pyridinium mononucleotide, forming C-Ni and two S-Ni bonds (3). Within the active site of enzyme, the nickel is additionally bound by a histidyl residue and in some cases the NPN cofactor is covalently tethered to a lysyl group. Biosynthesis of NPN is a three-step process. LarB uses nicotinic acid adenine dinucleotide (NaAD) as its substrate and catalyzes C5-carboxylation and phosphoanhydride hydrolysis to produce the dicarboxylated pyridine mononucleotide (P2CMN) (4). LarE catalyzes an ATP-dependent sulfur insertion reaction that converts P2CMN into a species with two thiocarboxylic acids (P2TMN) by sacrificial loss of a cysteinyl sulfur atom or by sulfur donation from a [4Fe-5S] cluster (5-6). LarC is a CTP-dependent nickel insertase or cyclometallase that transforms P2TMN into NPN (7-8). Recent developments in understanding the biosynthesis and utilization of the NPN cofactor will be described (9).https://cassyni-user-files-prod.s3.amazonaws.com/9h8XVwz7cgacbBCDyNKfxr https://cassyni.com/slides/outline/Nh1od9ydCaFss8tKT2WKg9 https://cassyni.com/events/Nh1od9ydCaFss8tKT2WKg9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HX7ArVAbGTAwZWmBG3YKQA https://cassyni.com/events/Nh1od9ydCaFss8tKT2WKg9?videoPreview=1 The onset of turbulence in shear flows - a matter of life and deathnohttps://cassyni.com/events/Nh1od9ydCaFss8tKT2WKg9?videoPreview=12021-03-04T12:00:00+00:003859.6Leeds Institute for Fluid DynamicsIn pipe, channel and Couette flow turbulence arises despite the linear stability of the laminar state and the transition is caused by finite amplitude perturbations. In the vicinity of the critical point turbulence is not space filling but appears in localized patches. Although the lifetime of individual patches is finite, prior to decay they may infect adjacent laminar regions and proliferate. Depending which of these processes dominates, eventually either the entire flow will relaminarise or turbulence survives. This overall situation is reminiscent to absorbing state phase transitions in statistical mechanics. As shown specifically for Couette flow the transition falls into the directed percolation universality class. In order to resolve the relevant time scales of the flow and to determine the respective critical exponents, experiments with excessively large aspect ratios and observation times are required. In addition I will discuss further complications that arise in pressure driven flows such as pipes and channels.https://cassyni-user-files-prod.s3.amazonaws.com/HX7ArVAbGTAwZWmBG3YKQA https://cassyni.com/events/PBfQfqd9e2ovruRD3To7wT/seminar/qa https://cassyni.com/slides/outline/PBfQfqd9e2ovruRD3To7wT https://cassyni.com/events/PBfQfqd9e2ovruRD3To7wT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UQgjF7cnrUtfKonwEsTjBc https://cassyni.com/events/PBfQfqd9e2ovruRD3To7wT?videoPreview=1 A Unifying Framework for Operator Learning via Neural Fieldsnohttps://cassyni.com/events/PBfQfqd9e2ovruRD3To7wT?videoPreview=12023-12-08T14:00:00+00:003436.16Department of Chemical EngineeringOperator learning is an emerging area of machine learning which aims to learn mappings between infinite dimensional function spaces and has led to the development of new architectures such as the Fourier Neural Operator, the DeepONet, and their extensions. In this talk I will uncover a previously unrecognized connection between existing operator learning architectures and conditioned neural fields used in computer vision. This results in a unified framework for explaining differences between popular operator learning architectures, and creates a bridge for adapting well-developed tools from computer vision for operator learning. In particular, we find all existing operator learning architectures are neural fields whose conditioning mechanisms are restricted to use only pointwise and/or global information. This motivates us to design new architectures which make use of a hierarchy of scales for conditioning a base neural field. By making use of multi-scale conditioning, we observe consistent performance gains and obtain state of the art results across a collection of challenging benchmarks in climate modelling and fluid dynamics. *joint work with Jacob Seidman, Hanwen Wang, Shyam Sankaran and George Pappas https://cassyni-user-files-prod.s3.amazonaws.com/UQgjF7cnrUtfKonwEsTjBc https://cassyni.com/events/RAFpraDFPs2gxchSQRf4N1/seminar/qa https://cassyni.com/slides/outline/RAFpraDFPs2gxchSQRf4N1 https://cassyni.com/events/RAFpraDFPs2gxchSQRf4N1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EWcegUodU6hhomG6XjJT1p https://cassyni.com/events/RAFpraDFPs2gxchSQRf4N1?videoPreview=1 Domain Engineering Concepts enabled by Topological Defectsnohttps://cassyni.com/events/RAFpraDFPs2gxchSQRf4N1?videoPreview=12024-03-27T23:15:00+00:002930.04The MacDiarmid Institute for Advanced Materials and NanotechnologyThe functionality of ferroelectric materials is intricately linked to their domain morphology. Recent research has unveiled dislocations and precipitates as effective tools for controlling the domains in ferroelectrics. Furthermore, topological electric structures are attracting attention, giving conceptually new opportunities for domain engineering. Here, we explore the possibility to use topologically protected vortex/anti-vortex structures to tailor the ferroelectric domains in polycrystalline hexagonal manganites. Unlike conventional ferroelectrics, like BaTiO3 and Pb(Zr,Ti)O3, we observe an inverted scaling behavior where larger grains yield smaller domains. This atypical scaling behavior is explained based on the interplay of the topologically protected vortices with elastic strain fields. We further demonstrate the harnessing of this unique interaction to engineer domain structures via external elastic stresses. The synergy of elastic strain and topological defects offers a novel approach for tailoring the electromechanical and dielectric performance of ferroelectrics, enhancing their potential in capacitor applications and domain wall-based nanoelectronics.https://cassyni-user-files-prod.s3.amazonaws.com/EWcegUodU6hhomG6XjJT1p https://cassyni.com/slides/outline/TdVr5zSsb9oBKZAzx7Zh5w https://cassyni.com/events/TdVr5zSsb9oBKZAzx7Zh5w/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6Xa5zvVVEA61haM3BJ4sZG https://cassyni.com/events/TdVr5zSsb9oBKZAzx7Zh5w?videoPreview=1 Altered propionate metabolism contributes to tumour progression and aggressivenessnohttps://cassyni.com/events/TdVr5zSsb9oBKZAzx7Zh5w?videoPreview=12023-12-21T14:00:00+00:003604.24Center for Cancer TrainingThe reprogramming of cellular metabolism for both the development of cancer and its progression to metastasis presents a ripe area of research. Far from simply existing as the process of breakdown and buildup of nutrients in the cell, cellular metabolism has become recognized as a fundamental determinant of cellular identity and function. It is now evident that certain metabolites can drive cancer progression and metastasis, functioning in autocrine, paracrine and endocrine fashions. We have previously demonstrated how a systemic age-induced increase of a single metabolite, contributes to poor cancer prognosis and increased cancer-related mortality in elderly patients, highlighting the importance of metabolic alterations in determining tumor progression. Building on these findings, we have identified that production of this age-related metabolite occurs in cancer cells through deregulation of its biosynthetic pathway and elicits a transcriptional reprogramming that enables cancer cells to attain the traits necessary for progression into metastatic disease.https://cassyni-user-files-prod.s3.amazonaws.com/6Xa5zvVVEA61haM3BJ4sZG https://cassyni.com/slides/outline/8NDHHLDQUJCJYy8W2oyPPj https://cassyni.com/events/8NDHHLDQUJCJYy8W2oyPPj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4JCoww2P7iLbVMifhz7mJN https://cassyni.com/events/8NDHHLDQUJCJYy8W2oyPPj?videoPreview=1 Top-down vs. Traditional Anatomical Endoscopic Enucleation of the Prostate (AEEP): Does the direction of enucleation matter?nohttps://cassyni.com/events/8NDHHLDQUJCJYy8W2oyPPj?videoPreview=12024-02-19T15:00:00+00:003201.08Research Seminars by Springer NatureBACKGROUND: The top-down holmium laser enucleation of the prostate (HoLEP) technique recently emerged as a safe and effective modification of traditional HoLEP. In our randomized controlled trial, we compared intraoperative and postoperative outcomes of traditional and top-down HoLEP for the treatment of benign prostatic hyperplasia (BPH) in patients with a prostate size ≥80 g. METHODS: One-hundred patients with BPH and a prostate volume ≥80 cc participated in this prospective randomized controlled trial. Outcome measures were collected and compared, including IPSS, QoL, flow rate, PVR, IIEF-15, PSA, and TRUS prostate volume changes. Perioperative complications were also recorded. All patients were followed up at 1, 3, 6, and 12 months. RESULTS: There were no significant differences in preoperative baseline characteristics between the two surgical groups. The median prostate volume for the traditional and top-down HoLEP groups was 107 and 102 cc, respectively. The operative parameters and postoperative outcomes were comparable for both cohorts. The median enucleation time for traditional HoLEP was 60min, which was not significantly longer than that of top-down HoLEP (52min) (p=0.07). At 3 months follow-up, there was no statistically significant difference in transient stress urinary incontinence (SUI) in the traditional HoLEP (4.1%) versus the top-down HoLEP group (2.2%), (p =0.61). There were no significant differences in functional and sexual outcomes between the two groups at 12 months. CONCLUSIONS: The HoLEP procedure significantly improves patients’ urinary functional outcomes and has comparable postoperative outcomes regardless of the technique utilized.https://cassyni-user-files-prod.s3.amazonaws.com/4JCoww2P7iLbVMifhz7mJN https://cassyni.com/events/2w5dmp6deG7EA6tGRtybQH/seminar/qa https://cassyni.com/slides/outline/2w5dmp6deG7EA6tGRtybQH https://cassyni.com/events/2w5dmp6deG7EA6tGRtybQH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/A4cjHTikwmzjX8vnGd6o9p https://cassyni.com/events/2w5dmp6deG7EA6tGRtybQH?videoPreview=1 Introduction to the 5th Biometals Webinars, Managing Manganese in Bacillus subtilis, SARS‑CoV2 Nsp1 is a metal‑dependent DNA and RNA endonucleasenohttps://cassyni.com/events/2w5dmp6deG7EA6tGRtybQH?videoPreview=12024-05-07T13:00:00+00:004434.04BioMetalsWelcome to the 5th international webinars series For those who don't already know, these webinars have been set up by the international Biometals society and the journal Biometals with the help of Cassyni platform. • The aim is to promote research in the field of metal interactions in biology and to encourage the interdisciplinary exchange of information at international level. Manganese (Mn) in the spotlight today! Mn, just before iron in the periodic table, is importance is quite often under evaluated compare to iron! As iron Mn is essential but may be toxic due to mainly its redox properties. Mn is a key cofactor in many enzymes and vital system such as photosynthesis… where the tetranuclear manganese cofactor in photosystem 2 catalyzes the key reaction of oxygen production….but The Mn Superoxide dismutase is also a key actor…and many other enzymes contain Mn as cofactor prokaryotic, eukaryotes…and viral!!!! Intracellular or excreted welcome two speakers: John Helmann from Cornell University will be talking about Manganese homeostasis in his favorite playground Bacillus subtilis The 2nd speaker, Celia Romão will be talking about Manganese in a metal‑dependent endonuclease, not just any enzyme, but the one encoded by nsp1, one of the 16 sarsCov2 genes! Bacteria must adapt to both metal ion limitation and excess. In the model Gram-positive bacterium Bacillus subtilis, the MntR (manganese transport regulator) protein binds Mn(II), represses uptake genes, and activates two genes (mneP, mneS) encoding cation diffusion facilitator proteins that export Mn(II). Genetic studies of mutants dysregulated for Mn homeostasis (mntR) or lacking the major Mn efflux pumps (mneP mneS) revealed a class of mutations with increased expression or activity of two TerC family membrane proteins, MeeF(YceF) and MeeY(YkoY). MeeF and MeeY (metalation of exoenzymes) are Mn efflux proteins that function to support metalation of enzymes that function outside the cell membrane. Unlike MneP and MneS, the MeeF and MeeY proteins do not play a major role in resistance to elevated Mn, although mutations can increase their efflux activity. FY mutant strains, with deletions of both meeF and meeY, are slow growing due to defects in protein secretion and a reduced ability to metalate a key enzyme for cell wall synthesis, the Mn-dependent lipoteichoic acid synthase (LtaS). Consistent with a role in the metalation of Mn-requiring exoenzymes, the MeeY protein is regulated by a Mn-responsive riboswitch. We propose that MeeF and MeeY function, in part, in the co-translocational metalation of secreted enzymes. These findings highlight the challenge of properly metalating enzymes that function outside the cell and may prove relevant to studies of TerC homologs in plants and animals. Over recent years, we have been living under a pandemic, caused by the rapid spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2). One of the major virulence factors of Coronaviruses is the Non-structural protein 1 (Nsp1), known to suppress the host cells protein translation machinery, allowing the virus to produce its own proteins, propagate and invade new cells. To unveil the molecular mechanisms of SARS-CoV2 Nsp1, we have addressed its biochemical and biophysical properties in the presence of calcium, magnesium and manganese. Our findings indicate that the protein in solution is a monomer and binds to both manganese and calcium, with high affinity. Surprisingly, our results show that SARS-CoV2 Nsp1 alone displays metal-dependent endonucleolytic activity towards both RNA and DNA, regardless of the presence of host ribosome. These results show Nsp1 as new nuclease within the coronavirus family. Furthermore, the Nsp1 double variant R124A/K125A presents no nuclease activity for RNA, although it retains activity for DNA, suggesting distinct binding sites for DNA and RNA. Thus, we present for the first time, evidence that the activities of Nsp1 are modulated by the presence of different metals, which are proposed to play an important role during viral infection. This research contributes significantly to our understanding of the mechanisms of action of Coronaviruses.https://cassyni-user-files-prod.s3.amazonaws.com/A4cjHTikwmzjX8vnGd6o9p https://cassyni.com/slides/outline/DoLvnrLBJLHhgNiJ3SDHM7 https://cassyni.com/events/DoLvnrLBJLHhgNiJ3SDHM7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KbQcMesVBtMa5no4TZaa4e https://cassyni.com/events/DoLvnrLBJLHhgNiJ3SDHM7?videoPreview=1 Toeplitz operators on quotient domainsnohttps://cassyni.com/events/DoLvnrLBJLHhgNiJ3SDHM7?videoPreview=12023-02-09T15:00:00+00:003217.32Journal of Mathematical SciencesLet 𝐺 be a finite pseudo-reflection group and Ω be a bounded domain in ℂ𝑑 which is 𝐺-invariant. The quotient domain Ω/𝐺 is biholomorphically equivalent to a domain θ(Ω) where θ: Ω → θ(Ω) is a basic polynomial map. Prominent example of a quotient domain is the symmetrized polydisc 𝔾𝑑 in ℂ𝑑. In this case, the basic polynomial map is given by 𝑧 → (𝑠1(𝑧), 𝑠2(𝑧),⋯ 𝑠𝑑(𝑧)) from 𝔻𝑑 (unit polydisc in ℂ𝑑) to 𝔾𝑑 where 𝑠 𝑗(𝑧) is the 𝑗-th elementary symmetric polynomial. We study properties of Toeplitz operators on weighted Bergman spaces on θ(Ω) by establishing a connection of them with Toeplitz operators on weighted Bergman spaces on Ω. Results on zero product problem and commuting pairs of Toeplitz operators will be explained. Representation theory of 𝐺 and projections to isotypic components play an important role in our results. (Joint work with Gargi Ghosh)https://cassyni-user-files-prod.s3.amazonaws.com/KbQcMesVBtMa5no4TZaa4e https://cassyni.com/slides/outline/ALohU4oWE8R4egQjPmqKpH https://cassyni.com/events/ALohU4oWE8R4egQjPmqKpH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/461L7SMyWQTmn4mA3th5hG https://cassyni.com/events/ALohU4oWE8R4egQjPmqKpH?videoPreview=1 Benefits, costs and enabling conditions to achieve ‘water for all’ in rural and remote Australianohttps://cassyni.com/events/ALohU4oWE8R4egQjPmqKpH?videoPreview=12024-02-08T20:00:00+00:001766.56Nature WaterAustralia will not meet Sustainable Development Goal target 6.1, to “achieve universal and equitable access to safe and affordable drinking water for all” by 2030, unless water service provision is improved to hundreds of small (less than 10,000 residents), rural and remote (SRR) communities. We have estimated the national benefits of a programme to upgrade drinking water services to ensure ‘good quality’ for 395 Australian SRR communities using a stated preference survey of 3,523 participants reflective of the Australian population. Using multiple model estimates, we calculated the willingness to pay at between AUD 324 and AUD 847 per Australian household per year for 10 years. Aggregating across the relevant Australian population, we calculated the aggregate willingness to pay for water quality improvements at AUD 1.2–4.7 billion yr−1, or AUD 8.3–33.2 billion as a 10-year net present value. We further estimated the capital and operating costs to provide ‘good-quality’ drinking water in the 395 SRR communities under three scenarios; the costs range from AUD 0.51 to AUD 3.29 million per community and, in total, from AUD 0.2 billion to AUD 1.3 billion.https://cassyni-user-files-prod.s3.amazonaws.com/461L7SMyWQTmn4mA3th5hG https://cassyni.com/slides/outline/Cp3ihV38RRBZ1ctHwTjxYD https://cassyni.com/events/Cp3ihV38RRBZ1ctHwTjxYD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6iY5HsfqRUmWe2ancwBmuQ https://cassyni.com/events/Cp3ihV38RRBZ1ctHwTjxYD?videoPreview=1 Interfacial characterization of poly(pyrrole) films doped with SiO2 nanoparticles and their use as electrosorptive phase of caffeinenohttps://cassyni.com/events/Cp3ihV38RRBZ1ctHwTjxYD?videoPreview=12024-02-20T14:00:00+00:003443.64Electrochimica ActaIn this work, we show the electrosynthesis of poly(pyrrole) films in the presence of SiO2 nanoparticles to develop a hybrid electrode to study the adsorption properties based on the electrochemical and interfacial features of the modified electrode. The electrodes were carefully characterized using electrochemical techniques such as voltammetry and electrochemical impedance spectroscopy, demonstrating that the inclusion of SiO2 nanoparticles in the PPy films has improved the electroactivity of the conducting polymer, in terms of both kinetics and mass transport. The morphology of the electrodes was also investigated by scanning electron microscopy, demonstrating the high surface achieved by the electrodeposition of either PPy and PPy/nano-SiO2. The system was studied for the electroadsorption of caffeine where the applied potential at the substrate plays a key role in tax of the adsorbed specie, mostly due to the increase of van der Waals interactions, enhanced greatly by the presence of the SiO2 nanoparticles. Adsorption isotherms and modeled equivalent circuits were also adopted to further characterize the interfacial properties of the different electrodes synthesized herein.https://cassyni-user-files-prod.s3.amazonaws.com/6iY5HsfqRUmWe2ancwBmuQ https://cassyni.com/slides/outline/MD6cbjYwHZXGKRwAHt1TPj https://cassyni.com/events/MD6cbjYwHZXGKRwAHt1TPj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/MEaHBqDi6s7W1WYRep94iS https://cassyni.com/events/MD6cbjYwHZXGKRwAHt1TPj?videoPreview=1 Mechanochemistrynohttps://cassyni.com/events/MD6cbjYwHZXGKRwAHt1TPj?videoPreview=12022-04-13T16:00:00+00:009497.36Thieme GroupAlthough the history of mechanochemistry goes back centuries, with the rapid growth of articles about it, it is becoming clear that this once arcane discipline is becoming increasingly useful.https://cassyni-user-files-prod.s3.amazonaws.com/MEaHBqDi6s7W1WYRep94iS https://cassyni.com/slides/outline/PgLdq9nZUrHkgNQiqZv67f https://cassyni.com/events/PgLdq9nZUrHkgNQiqZv67f/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NxqtrDz3dy3qry5KSCGucz https://cassyni.com/events/PgLdq9nZUrHkgNQiqZv67f?videoPreview=1 Rising Stars in Organic Synthesis: Session 2nohttps://cassyni.com/events/PgLdq9nZUrHkgNQiqZv67f?videoPreview=12023-06-22T16:00:00+00:007276.44Thieme GroupNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/NxqtrDz3dy3qry5KSCGucz https://cassyni.com/events/LDoQWNFtQeR7eg7ABuY8aq/seminar/qa https://cassyni.com/slides/outline/LDoQWNFtQeR7eg7ABuY8aq https://cassyni.com/events/LDoQWNFtQeR7eg7ABuY8aq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KUjuNfrQzcjL6EZ6PjboKc https://cassyni.com/events/LDoQWNFtQeR7eg7ABuY8aq?videoPreview=1 Biomedical Fluid Mechanics: applications in urology and regenerative medicinenohttps://cassyni.com/events/LDoQWNFtQeR7eg7ABuY8aq?videoPreview=12024-05-24T15:00:00+00:003918.04Journal of Fluid MechanicsIn this talk, I will discuss two applications of biomedical fluid mechanics in urology and regenerative medicine, and present new theoretical models developed alongside complementary experimental approaches. Throughout the talk, I will highlight how the derivation and exploitation of reduced models that retain the essential physics, while remaining tractable, can provide mechanistic insights into these biomedical fluid flows, and discuss how the resulting insights can be exploited to drive new healthcare innovations. The first application will show how a detailed understanding of the fluid mechanics associated with medical devices used to treat kidney stones can be exploited to guide innovations in device operation and design with enhanced mass transport properties. The second application in regenerative medicine considers the complex interplay of cells, biomaterials, and bioreactors and microfluidic systems required for tissue growth, repair and regeneration. I will show how insights into the wealth of fluid mechanics challenges encountered in regenerative medicine, including fluid-structure interactions, reactive multiphase flows, and advective transport, can guide the development of new regenerative medicine therapies and protocols.https://cassyni-user-files-prod.s3.amazonaws.com/KUjuNfrQzcjL6EZ6PjboKc https://cassyni.com/events/WbR6UiqudG3YBBQJD1V2GM/seminar/qa https://cassyni.com/slides/outline/WbR6UiqudG3YBBQJD1V2GM https://cassyni.com/events/WbR6UiqudG3YBBQJD1V2GM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2dVQXGqVJPTRuxBG9qTG8W https://cassyni.com/events/WbR6UiqudG3YBBQJD1V2GM?videoPreview=1 Epitaxial HoN thin films: An investigation of the structural, electronic, and magnetic propertiesnohttps://cassyni.com/events/WbR6UiqudG3YBBQJD1V2GM?videoPreview=12024-03-13T20:00:00+00:003400.72School of Chemical and Physical SciencesWe report our study on the growth of HoN thin films on MgO (100) and LaAlO3 (100) substrates. By using molecular beam epitaxy, we thermally evaporate holmium in an atmosphere of molecular nitrogen, forming HoN at slow rates, moderate temperatures and pressures. We are able to carefully and systematically vary the growth conditions, thereby tuning the nitrogen content of our samples. We explore the differences in the growth window by looking at the crystalline structure and composition of the films deposited on the different substrates. We find that HoN has an epitaxial, well-ordered growth on LaAlO3, in contrast to the three-dimensional growth that occurs on MgO. Using a combination of in situ electron diffraction and x-ray spectroscopies, as well as ex situ x-ray diffraction and SQUID magnetometry, we investigate the structural, electronic, and magnetic properties of the epitaxial HoN films.https://cassyni-user-files-prod.s3.amazonaws.com/2dVQXGqVJPTRuxBG9qTG8W https://cassyni.com/slides/outline/Rew41tNfEgWWn5gxCXn2YD https://cassyni.com/events/Rew41tNfEgWWn5gxCXn2YD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/MhhGLqt7MQoYqmQSQEC2X8 https://cassyni.com/events/Rew41tNfEgWWn5gxCXn2YD?videoPreview=1 Trafficking and Healthnohttps://cassyni.com/events/Rew41tNfEgWWn5gxCXn2YD?videoPreview=12023-04-05T15:00:00+00:002355.24Imperial College Renal and Transplant CentreNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/MhhGLqt7MQoYqmQSQEC2X8 https://cassyni.com/events/8rtWSeNpK7g8NS81pv6MZw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KUyQSB5TCNoCMCDyJ11adt https://cassyni.com/events/X64hXQVS4ibbAwwBoSmpXf/seminar/qa https://cassyni.com/slides/outline/X64hXQVS4ibbAwwBoSmpXf https://cassyni.com/events/X64hXQVS4ibbAwwBoSmpXf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Aq5egztAHV5gzPMZ5WrAQn https://cassyni.com/events/X64hXQVS4ibbAwwBoSmpXf?videoPreview=1 Origami-paper microfluidic devices for rapid and on-site wastewater surveillancenohttps://cassyni.com/events/X64hXQVS4ibbAwwBoSmpXf?videoPreview=12024-05-13T11:00:00+00:004744.04ElsevierPathogen detection is of significant importance for both biomedical diagnostics (e.g., infectious disease) and environmental analysis, e.g., pathogen contamination in drinking water), SARS-CoV-2 in wastewater for early warning of pandemic. Here we present a low-cost, deployable paper-based biosensor device for rapid analysis of pathogens for disease diagnosis and public health. We will show the capability of paper-origami devices for field-testing for veterinary diagnosis in India, and for malaria testing in a local primary school in Africa, as well as a recent clinical sample testing of Hepatitis C virus (HCV). This device has been developed to trace the source of SARS-CoV-2 in wastewater for early warning of the pandemic, supported by a UK national wastewater epidemiology surveillance programme for COVID-19. It was demonstrated for the field-testing in local quarantine hotel in London for SARS-CoV-2 and influenza virus and beyond. https://cassyni-user-files-prod.s3.amazonaws.com/Aq5egztAHV5gzPMZ5WrAQn https://cassyni.com/slides/outline/6PeVDE9C7pue1VeTHEBir1 https://cassyni.com/events/6PeVDE9C7pue1VeTHEBir1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Q9pP15WHSGX24eHEDL6hdY https://cassyni.com/events/6PeVDE9C7pue1VeTHEBir1?videoPreview=1 Continuous Glucose Sensors and accuracy in people with diabetes undergoing haemodialysisnohttps://cassyni.com/events/6PeVDE9C7pue1VeTHEBir1?videoPreview=12023-08-02T14:00:00+00:001789.08Imperial College Renal and Transplant CentreNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/Q9pP15WHSGX24eHEDL6hdY https://cassyni.com/events/3vQTyouZvY96yLQfpSPMqo/seminar/qa https://cassyni.com/slides/outline/3vQTyouZvY96yLQfpSPMqo https://cassyni.com/events/3vQTyouZvY96yLQfpSPMqo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6TqVwp2VqLQ3ZyH3uKQW94 https://cassyni.com/events/3vQTyouZvY96yLQfpSPMqo?videoPreview=1 Decoding Visual Attention: from 3D Gaze to Social Gaze inference in Everyday Scenesnohttps://cassyni.com/events/3vQTyouZvY96yLQfpSPMqo?videoPreview=12024-04-04T10:30:00+00:002738.04Journal on Image and Video ProcessingBeyond words, non-verbal behaviors (NVB) are known to play important roles in face-to-face interactions. However, decoding non-verbal behaviors is a challenging problem that involves both extracting subtle physical NVB cues and mapping them to higher-level communication behaviors or social constructs. This is particularly the case for gaze, one of the most important non-verbal behaviors with functions related to communication and social signaling. Indeed, as a display of attention and interest, gaze is a fundamental cue in understanding people's activities, behaviors, and state of mind, and plays an important role in many applications and research fields, such as the design of intuitive human-computer or robot interfaces, or for medical diagnosis, like assessing Autism Spectrum Disorders (ASD) in children. However, decoding the visual attention of others —that is, estimating their gaze (3D line of sight) and Visual Focus of Attention (VFOA)— is a challenging task, even for humans. It often requires not only inferring an accurate 3D gaze direction from the person's face and eyes but also understanding the global context of the scene (what is going on, where are people, are people interacting, where are salient items), including the person’s activity and situation as well as the scene structure to detect obstructions in the line of sight or apply attention priors that humans typically have when observing others. Due to this duality, two lines of research have been followed in recent years. The first one focused on improving appearance-based 3D gaze estimation from images and videos, while the second investigated gaze following —the task of estimating the 2D pixel location of where a person looks in an image. In this presentation, I will discuss different methods that address the two cases mentioned above. I will first focus on several methodological ideas on how to improve 3D gaze estimation, including approaches to build personalized models through few-shot learning and gaze redirection eye synthesis, differential gaze estimation, or taking advantage of priors on social interactions to obtain weak labels for model adaptation. In the second part, I will introduce recent models aiming at estimating gaze targets in the wild, the first one taking advantage of different modalities and applicable to privacy-sensitive settings, and the second one leveraging new depth estimation methods yielding geometry-preserving point clouds and avoiding distorted reconstructed 3D scenes. I will discuss current limitations and directions for future research. This research was suported by the Swiss National Science Foundation.https://cassyni-user-files-prod.s3.amazonaws.com/6TqVwp2VqLQ3ZyH3uKQW94 https://cassyni.com/events/AqUvdNxv4wttU9QFBsxHzV/seminar/qa https://cassyni.com/slides/outline/AqUvdNxv4wttU9QFBsxHzV https://cassyni.com/events/AqUvdNxv4wttU9QFBsxHzV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/SGDGjskHNGr1B2GnH1MbzE https://cassyni.com/events/AqUvdNxv4wttU9QFBsxHzV?videoPreview=1 Raising Ambition in Net Zero Flightnohttps://cassyni.com/events/AqUvdNxv4wttU9QFBsxHzV?videoPreview=12024-04-26T11:00:00+00:003489.36Brahmal Vasudevan Institute for Sustainable AviationRapid action is required by both industry and governments if we are to establish a pathway to achieve zero-emission aviation by 2050. Cambridge had been leading a team that has been developing the 2030 Sustainable Aviation Goals, a set of actions that, if implemented by 2030, would significantly reduce the time required to achieve zero-emission aviation. This work is supported by the Aviation Impact Accelerator (AIA), an international group of experts who are developing evidence-based, whole-system modelling tools necessary to explore how policy, technology, and system integration could be utilized to accelerate change. The talk will preview the four 2030 Sustainable Aviation Goals, each of which has been specifically targeted to raise ambition in a particular area of aviation. The first goal is designed to provide the policies necessary to ensure that Sustainable Aviation Fuels (SAF) can be delivered in a truly sustainable way. The second goal is designed to accelerate the demonstration of the key technologies necessary to develop a long-haul hydrogen aircraft in time to achieve a significant climate impact by 2050. The third goal is designed to unlock the aviation sector-wide changes necessary to achieve a 50% reduction in fuel burn per passenger km by 2050. The final goal is designed to deploy the large-scale contrail avoidance trials necessary to accelerate the implementation of a global contrail avoidance scheme.https://cassyni-user-files-prod.s3.amazonaws.com/SGDGjskHNGr1B2GnH1MbzE https://cassyni.com/events/MiDob7xXa9piUEVFhEYASh/seminar/qa https://cassyni.com/slides/outline/MiDob7xXa9piUEVFhEYASh https://cassyni.com/events/MiDob7xXa9piUEVFhEYASh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2zZJRxSrpSTLjdA1BSNz5U https://cassyni.com/events/MiDob7xXa9piUEVFhEYASh?videoPreview=1 Demystifying Transfersnohttps://cassyni.com/events/MiDob7xXa9piUEVFhEYASh?videoPreview=12024-04-23T08:00:00+00:001903.76Topics at the heart of our communityTransfers represent an important aspect for content retention strategy in all journals. This presentation outlines the main benefits - and opportunities for growth - provided by transfers for Springer Nature Editors and their journals. Armed with data and examples, we show that in the majority of cases, a rejection does not mean a manuscript isn't worthy of publication. One journal's rejection can truly be another’s opportunity.https://cassyni-user-files-prod.s3.amazonaws.com/2zZJRxSrpSTLjdA1BSNz5U https://cassyni.com/events/JFgaGLRrVwx5SYBh3aACus/seminar/qa https://cassyni.com/slides/outline/JFgaGLRrVwx5SYBh3aACus https://cassyni.com/events/JFgaGLRrVwx5SYBh3aACus/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AWcxh351bGXsvfaGeLRuP4 https://cassyni.com/events/JFgaGLRrVwx5SYBh3aACus?videoPreview=1 Roundtable: Science in the Makingnohttps://cassyni.com/events/JFgaGLRrVwx5SYBh3aACus?videoPreview=12024-04-19T13:30:00+00:006246.68Royal Society PublishingIn 1665, the first issue of the Royal Society trailblazing scientific journal, the Philosophical Transactions appears. Publishing research across the sciences as reported by and to the Fellows of the Royal Society, the Philosophical Transactions has showcased the work of preeminent scientific minds of the past 370 years. Today, Science in the Making takes the Philosophical Transactions as its starting point and dives back into the archives to go beyond the printed page and allows users to discover how science was made, discussed, and shared since the very beginnings of its history. As we approach the 1-year anniversary of the launch of Science in the Making, this roundtable will discuss how the project came about, how the platform works, and how historians of science are practically using it as a resource. https://cassyni-user-files-prod.s3.amazonaws.com/AWcxh351bGXsvfaGeLRuP4 https://cassyni.com/events/XbBtWnu2MJu3KkVHCoJXad/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4x95djFuTgy8gasT8FeASi https://cassyni.com/events/7PRHFJCJqsm9A4jSH21EAH/seminar/qa https://cassyni.com/slides/outline/7PRHFJCJqsm9A4jSH21EAH https://cassyni.com/events/7PRHFJCJqsm9A4jSH21EAH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KgXT2NuzurSgfmiXBGGd5Y https://cassyni.com/events/7PRHFJCJqsm9A4jSH21EAH?videoPreview=1 Towards Reentry Capsule Dynamic Stability Prediction: Recent Experience using PyFR for Capsule Wake Flownohttps://cassyni.com/events/7PRHFJCJqsm9A4jSH21EAH?videoPreview=12024-09-05T16:00:00+00:002452.84PyFRPlanetary reentry capsules are typically blunt shaped to keep the strong leading bow shock away from the capsule and reduce the thermal load on the surface. Although such shapes are preferred for heating in the hypersonic regime of the flight trajectory, they present significant challenges for dynamic stability at the low supersonic and subsonic Mach number regimes. The unsteady wake behind the blunt body exerts forces and moments on the after-body which dictate the stability character of the capsule. Characterization of this unsteady wake is crucial to understand the dynamic stability behavior. Towards the goal of predicting capsule dynamic stability characteristics using CFD, results from a recent PyFR study of the wake behind the Viking '75 reentry capsule will be presented. Also current effort to extend the capabilities of the solver for free-flight prediction will be mentioned. https://cassyni-user-files-prod.s3.amazonaws.com/KgXT2NuzurSgfmiXBGGd5Y https://cassyni.com/slides/outline/U8efC1NMH72QJ4BiZ8va3o https://cassyni.com/events/U8efC1NMH72QJ4BiZ8va3o/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4yKB8GQtZaQo6YoirpVYEa https://cassyni.com/events/U8efC1NMH72QJ4BiZ8va3o?videoPreview=1 AI/ML+Physics: Recap and Summarynohttps://cassyni.com/events/U8efC1NMH72QJ4BiZ8va3o?videoPreview=12024-04-26T10:00:00+00:001440.28Brunton LabThis video provides a brief recap of this introductory series on Physics Informed Machine Learning. We revisit the five stages of machine learning, and how physics may be incorporated into these stages. We also discuss architectures, symmetries, the digital twin, applications in engineering, and the importance of dynamical systems and controls benchmarks. SLB acknowledges support from the National Science Foundation AI Institute in Dynamic Systems and from The Boeing Company.https://cassyni-user-files-prod.s3.amazonaws.com/4yKB8GQtZaQo6YoirpVYEa https://cassyni.com/slides/outline/EJVjtsFezHWvesj1eTaAJy https://cassyni.com/events/EJVjtsFezHWvesj1eTaAJy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UrHLUigdU8ZNYkK8pyyAJa https://cassyni.com/events/EJVjtsFezHWvesj1eTaAJy?videoPreview=1 SINDy-PI: A robust algorithm for parallel implicit sparse identification of nonlinear dynamicsnohttps://cassyni.com/events/EJVjtsFezHWvesj1eTaAJy?videoPreview=12021-11-12T14:00:00+00:001137.2Brunton LabIn this video, Kadierdan Kaheman describes SINDy-PI: A robust algorithm for parallel implicit sparse identification of nonlinear dynamics. The SINDy-PI overcomes the difficulties of using SINDy to identify the rational system or implicit dynamics and made it possible to directly extract the physical laws from data.https://cassyni-user-files-prod.s3.amazonaws.com/UrHLUigdU8ZNYkK8pyyAJa https://cassyni.com/events/EoAy4BR4q6zkULiXSZh8VB/seminar/qa https://cassyni.com/slides/outline/EoAy4BR4q6zkULiXSZh8VB https://cassyni.com/events/EoAy4BR4q6zkULiXSZh8VB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/YawaxrpS1ekYowFeCGDq9Y https://cassyni.com/events/EoAy4BR4q6zkULiXSZh8VB?videoPreview=1 Vortex dynamics in an oscillating flownohttps://cassyni.com/events/EoAy4BR4q6zkULiXSZh8VB?videoPreview=12024-11-05T15:00:00+00:003314.32Experiments in FluidsIn this seminar I will present recent research into the interaction between vortex shedding from consecutive inline bodies (cylinders upstream of a conical bluff body) in an oscillating flow field. The motivation was the discovery of a method to control thermoacoustic instabilities in premixed flames stabilised by a bluff body. By placing an array of cylinders upstream of the flame, it was found that lock-in between vortex shedding from cylinders and the bluff body due to an applied acoustic field could be used to damp or drive thermoacoustic instabilities via interference. To understand the underlying vortex dynamics, PIV and hot wire experiments were undertaken. It was found that the lock-in between the vortex shedding from the cylinders is amplified at the expected Strouhal number of 0.2. Results show that the forcing frequency, symmetric vortex shedding from the cylinders and the bluff body is the dominant mode. However, when the forcing frequency approaches twice the natural shedding frequency of the cylinders, spectra exhibited peaks at both the forcing frequency and a sub-harmonic, hallmarks of classical lock-in of the transverse (VK street) vortex shedding mode. This prompted us to revisit the phenomenon vortex lock-in for a single circular cylinder in an oscillating flow but with a new twist by placing the cylinder at the node and anti-nodal positions of a standing wave to assess the lock-in behaviour. Velocity fields reveal the existence of bimodal shedding during lock-in - both symmetric and transverse modes. POD was used to investigate the symmetric and transverse shedding modes revealing that symmetric shedding is inherent in the near wake region only. These results led to a proposed scaling based on Strouhal number/reduced velocity to predict the amplitudes of the velocity fluctuations required for lock-in.https://cassyni-user-files-prod.s3.amazonaws.com/YawaxrpS1ekYowFeCGDq9Y https://cassyni.com/slides/outline/Gmjm8HVHBaHR1pCaC9Uo2u https://cassyni.com/events/Gmjm8HVHBaHR1pCaC9Uo2u/abstract https://cassyni-user-files-prod.s3.amazonaws.com/YPV5gkvnzWSTQ89PETt3zv https://cassyni.com/events/Gmjm8HVHBaHR1pCaC9Uo2u?videoPreview=1 Multi-scale Modeling and Simulations using Digital Twinsnohttps://cassyni.com/events/Gmjm8HVHBaHR1pCaC9Uo2u?videoPreview=12023-10-12T14:00:00+00:003279.0AI Institute in Dynamic SystemsNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/YPV5gkvnzWSTQ89PETt3zv https://cassyni.com/slides/outline/BqFifT22nzkPciVEBfmoJm https://cassyni.com/events/BqFifT22nzkPciVEBfmoJm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/85QbUudkPauiYcJG9i2TEE https://cassyni.com/events/BqFifT22nzkPciVEBfmoJm?videoPreview=1 Panel discussion: Publishingnohttps://cassyni.com/events/BqFifT22nzkPciVEBfmoJm?videoPreview=12024-06-06T20:50:00+00:003865.2New Phytologist Foundation No abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/85QbUudkPauiYcJG9i2TEE https://cassyni.com/slides/outline/NCves4dppLEK7PwPh1VJXo https://cassyni.com/events/NCves4dppLEK7PwPh1VJXo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4Sf4y39NinwmueuLthxutA https://cassyni.com/events/NCves4dppLEK7PwPh1VJXo?videoPreview=1 Keynote talk "Disinfection-mediated selection of the drinking water microbiome"nohttps://cassyni.com/events/NCves4dppLEK7PwPh1VJXo?videoPreview=12024-09-17T13:00:00+00:001653.08Microbiome Virtual International ForumMost microbes in drinking water do not pose a human health risk, but the presence of pathogenic microbes can have severe public health implications. Hence, nearly all drinking water treatment technologies designed to manage microbial communities are intended to either inactivate, starve, or remove microorganisms during treatment and minimize growth during water distribution. Yet, every liter of drinking water can contain tens of millions of diverse microorganisms. How does the drinking water microbiome persist within the drinking water distribution systems despite chronic disinfectant stress and nutrient deprivation? This talk will present hypotheses based on field data on potential ecological and physiological mechanisms underpinning the persistence (and sometimes proliferation) of the drinking water microbiome. Systematically testing these hypotheses under field-relevant conditions has the potential to shift our approaches to microbial management of drinking water systems from a pathogen-centric to a microbiome-inclusive framework.https://cassyni-user-files-prod.s3.amazonaws.com/4Sf4y39NinwmueuLthxutA https://cassyni.com/slides/outline/PCFV54Sm6cGBvdTo5Yu4yK https://cassyni.com/events/PCFV54Sm6cGBvdTo5Yu4yK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HkT58JhfQVbh8LrSQU7HtJ https://cassyni.com/events/PCFV54Sm6cGBvdTo5Yu4yK?videoPreview=1 Microbiome and Women's Healthnohttps://cassyni.com/events/PCFV54Sm6cGBvdTo5Yu4yK?videoPreview=12024-06-11T15:00:00+00:002492.92Microbiome Virtual International Forum Panel discussion of the Microbiome and Women's Health eventhttps://cassyni-user-files-prod.s3.amazonaws.com/HkT58JhfQVbh8LrSQU7HtJ https://cassyni.com/events/QBVSwAi3AoWyesRSSbGy5X/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KoohL9FTpD43G54BFE5xfQ https://cassyni.com/events/JkMoRebGLmRuG1BCqgHB65/seminar/qa https://cassyni.com/slides/outline/JkMoRebGLmRuG1BCqgHB65 https://cassyni.com/events/JkMoRebGLmRuG1BCqgHB65/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Eqog7EbKVbjmV5uLd85tEr https://cassyni.com/events/JkMoRebGLmRuG1BCqgHB65?videoPreview=1 "Beautiful, young, white, and blonde". How Image Generative AI Reinforces Harmful Gender Normsnohttps://cassyni.com/events/JkMoRebGLmRuG1BCqgHB65?videoPreview=12024-09-20T04:10:00+00:003032.64Linguistics and Applied Language StudiesImage generative artificial intelligence (AI) platforms represent a new, and sometimes troubling, lens for the articulation of gender. Text prompts such as an attractive woman with long wavy hair […] glamorous pin-ups, perfect anatomy, perfect posture (Midjourney, 2023) creates images for users’ consumption at a rate of 34 million per day (Attie, 2023), indicating that this technology is poised to play a dominant role in the transmission, maintenance, and intensification of gender stereotypes. Employing a critical stance, corpus linguistics software AntConc (Anthony, 2024) was used to analyse users’ text prompts, focusing on gendered, gender-neutral, and gender-connotative noun forms alongside adjectival collocates. Subsequently, a social semiotically-informed multimodal analysis was used on selected images, presented as a case study to exemplify and highlight the corpus linguistics findings. Bathes described photographs in the media as having “passed through the filter of culture” (1981:16). While generative AI has precipitated a transformative shift in our communication landscape, it appears this cultural filter is still being applied. Critical analysis of this issue places sociolinguists and scholars from other interested fields at the forefront of discussions aimed at identifying and mitigating the propagation of gender hegemonies via image generative AI. https://cassyni-user-files-prod.s3.amazonaws.com/Eqog7EbKVbjmV5uLd85tEr https://cassyni.com/slides/outline/SA5s7uJ8vdjjkahfoZ8uW5 https://cassyni.com/events/SA5s7uJ8vdjjkahfoZ8uW5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VngbZWgafRgKf5U7MqjR8 https://cassyni.com/events/SA5s7uJ8vdjjkahfoZ8uW5?videoPreview=1 Macroecological correlates of Darwinian shortfalls across terrestrial vertebratesnohttps://cassyni.com/events/SA5s7uJ8vdjjkahfoZ8uW5?videoPreview=12024-07-15T12:00:00+00:001625.12Royal Society PublishingMost described species have not been explicitly included in phylogenetic trees—a problem named the Darwinian shortfall—due to a lack of molecular and/or morphological data, thus hampering the explicit incorporation of evolution into large-scale biodiversity analyses. We investigate potential drivers of the Darwinian shortfall in tetrapods, a group where at least one-third of described species still lack phylogenetic data, thus necessitating the imputation of their evolutionary relationships in fully-sampled phylogenies. We show that the number of preserved specimens in scientific collections is the main driver of phylogenetic knowledge accumulation, highlighting the major role of biological collections in unveiling novel biodiversity data and the importance of continued sampling efforts to reduce knowledge gaps. Additionally, large-bodied and wide-ranged species, as well as terrestrial and aquatic amphibians and reptiles, are phylogenetically better known. Therefore, future efforts should prioritize phylogenetic research on organisms that are narrow-ranged, small-bodied, and underrepresented in scientific collections, such as fossorial species. Addressing the Darwinian shortfall will be imperative for advancing our understanding of evolutionary drivers shaping biodiversity patterns and implementing comprehensive conservation strategies.https://cassyni-user-files-prod.s3.amazonaws.com/VngbZWgafRgKf5U7MqjR8 https://cassyni.com/events/7t6WQcMighExyXix588CLV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/F1VBhcooxehWrSPkVsSFiN https://cassyni.com/events/FHpa6s4bGZYoU7FR2zyvkV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2cFHx6icZwfwm6khAvPeRU https://cassyni.com/events/KjgddeQCd3Tn5EhcEDgwXb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Tn2dyiUKsVgJpH9KhBtsGS https://cassyni.com/events/Y5tjnjaKbVJdxuwRCaFffj/seminar/qa https://cassyni.com/slides/outline/Y5tjnjaKbVJdxuwRCaFffj https://cassyni.com/events/Y5tjnjaKbVJdxuwRCaFffj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9DKZgDUMPCqmxE56KY8gWA https://cassyni.com/slides/outline/Sem6HDTYmTDZa3hBbfFsgH https://cassyni.com/events/Sem6HDTYmTDZa3hBbfFsgH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EkV99zjyhytWJvGB14aGAa https://cassyni.com/events/Sem6HDTYmTDZa3hBbfFsgH?videoPreview=1 The effect of turbulence: From walls to gas-liquid interfacesnohttps://cassyni.com/events/Sem6HDTYmTDZa3hBbfFsgH?videoPreview=12024-11-06T14:00:00+00:002731.04Department of AeronauticsTurbulence is pervasive in real-world flows, yet it is often studied in idealised environments. From wall-bounded flows developing in laminar freestreams to gas-liquid (air-water) interfaces where turbulence is parameterised or neglected, these simplified scenarios reveal fundamental physics but fall short of capturing complex, real-world behaviour. Our findings show that external turbulence above a wall-bounded flow can significantly alter wall shear stress and may even lead to “devolution” of the boundary layer. We extend this approach to air-water interfacial flows, examining the interaction between surface waves and subsurface turbulence, with a focus on enstrophy enhancement and wave scattering. Moreover, our results demonstrate that turbulence can increase the rate of environmentally significant gas exchange—such as O₂ and CO₂ transfer across the air-water interface—by up to 45%. The talk will also showcase recent advancements in flow measurements, including the use of quantifiable laser-induced fluorescence to map O₂ concentration in water while simultaneously capturing the velocity field and surface topology. Additionally, we introduce a novel co-flowing air-water facility equipped with active turbulence grids in each phase, allowing for independent control of turbulence in the air and water.https://cassyni-user-files-prod.s3.amazonaws.com/EkV99zjyhytWJvGB14aGAa https://cassyni.com/slides/outline/5uXiLWHWLDxJS4EuKYLXnm https://cassyni.com/events/5uXiLWHWLDxJS4EuKYLXnm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VTWHVKaqVoHWFrcExtgkAa https://cassyni.com/events/5uXiLWHWLDxJS4EuKYLXnm?videoPreview=1 The human virome in health and diseasenohttps://cassyni.com/events/5uXiLWHWLDxJS4EuKYLXnm?videoPreview=12021-11-09T18:00:00+00:001428.04Microbiome Virtual International Forum Viruses are the numerically most abundant biological entities on Earth. The lecture will review approaches for studying the human-associated virome. The lecture will overview results from the field, then focus on two recent studies. The first characterizes the mechanism of colonization of human neonates by viruses. Neonates begin life sterile, but by one month virus-like particles are detectable in stool at a billion per gram. Multiple research strategies show that prophage induction provides a first wave of viral colonization. Viruses that grow on human cells appear later, and abundance of these viruses are negatively associated with breast feeding. Thus colonization of the gut of neonates appears to be step-wise, first by prophages induced from pioneer bacteria, and secondly by viruses infecting human cells, which is inhibited by breastfeeding. The second reports on studies of the virome dark matter, and the identification a new family of human-associated oro respiratory viruses recovered from the viral dark matter, named Redondoviruses.https://cassyni-user-files-prod.s3.amazonaws.com/VTWHVKaqVoHWFrcExtgkAa https://cassyni.com/slides/outline/2SzV1ikqG25fQMwLfsxaFw https://cassyni.com/events/2SzV1ikqG25fQMwLfsxaFw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VAy3bewhG5VY6cvWhmYEwx https://cassyni.com/events/2SzV1ikqG25fQMwLfsxaFw?videoPreview=1 Scaling laws in fluid mechanics: from computational optimization to mathematical analysisnohttps://cassyni.com/events/2SzV1ikqG25fQMwLfsxaFw?videoPreview=12022-11-02T14:00:00+00:003650.04Department of Aeronautics and Astronautics"This talk will consider the problem of how to predict time-averaged statistics of fluid flows as functions of external forcing parameters. For example, in aircraft design, one would like to know the drag on an aircraft’s wing as a function of its flight-velocity; or one may want to know the rate of heat transfer in a layer of fluid as a function boundary heating. Having knowledge of such scaling laws is of fundamental importance in the design of fluid mechanical systems. However, proving rigorous statements is challenging since important flow statistics (drag, heat transfer) depend on the chaotic solutions to nonlinear partial differential equations (Navier-Stokes, Raleigh-Bénard, etc.). A powerful approach to obtaining scaling laws is the so-called background method, popularised by Constantin and Doering in the 1990s, in which emergent flow statistics can be formally bounded by solving variational optimization problems. This approach led to many celebrated fundamental discoveries, most notably for the prediction of convective heat transfer in Raleigh-Bénard convection. This talk will discuss a recent numerical approach to implementing the background method, based on the convex optimization technique of semidefinite programming. We will show how semidefinite programming allows one to derive finite-dimensional optimization problems which rigorously approximate the infinite-dimensional variational problems required to implement the background method. Further, we will discuss how insights gained from the numerical solution to these problems can be used to inspire analytical proofs of scaling laws for several problems in turbulent convection." Image credit: [Bozhin Karaivanov (Unsplash)](https://unsplash.com/photos/a-close-up-of-a-piece-of-paper-with-writing-on-it-dvMJR9-Drbs). Image credit: [Richard Horvath (Unsplash)](https://unsplash.com/photos/blue-and-white-heart-illustration-cPccYbPrF-A).https://cassyni-user-files-prod.s3.amazonaws.com/VAy3bewhG5VY6cvWhmYEwx https://cassyni.com/slides/outline/4vEWF8zTTJr9mJQuDZsCys https://cassyni.com/events/4vEWF8zTTJr9mJQuDZsCys/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4GSU8Tb57T4CEwDxamBnRk https://cassyni.com/events/4vEWF8zTTJr9mJQuDZsCys?videoPreview=1 Assembly and dysbiosis of the seaweed microbiomenohttps://cassyni.com/events/4vEWF8zTTJr9mJQuDZsCys?videoPreview=12022-04-12T11:00:00+00:002372.0Microbiome Virtual International Forum Seaweeds are a ubiquitous group of photosynthetic organisms that play an essential role in many aquatic ecosystems. Seaweeds also host complex microbiomes. While symbiotic interactions with these microbiomes are essential for seaweeds, we now also know that microorganisms can be responsible for negative outcomes, such as disease of the host. In this seminar I will firstly discuss how ecological principles such as the “lottery hypothesis” and “priority effects” determine how microbiomes assemble on seaweeds. Secondly, I will discuss how anthropogenic stressors can disturb the microbiome (i.e. cause dysbiosis) resulting in the proliferation of opportunistic pathogens leading to disease. Finally, I will describe recent studies that show mitigation of disease through the addition of beneficial microorganisms and their possible mode of action.https://cassyni-user-files-prod.s3.amazonaws.com/4GSU8Tb57T4CEwDxamBnRk https://cassyni.com/slides/outline/CKxZwPhL3B9zFswNBSiwPs https://cassyni.com/events/CKxZwPhL3B9zFswNBSiwPs/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TkYwCX39tetMvmr6vzUEzz https://cassyni.com/events/CKxZwPhL3B9zFswNBSiwPs?videoPreview=1 Effective binning of metagenomic contigs using contrastive multi-view representation learningnohttps://cassyni.com/events/CKxZwPhL3B9zFswNBSiwPs?videoPreview=12024-02-27T11:00:00+00:00610.04Microbiome Virtual International Forum Contig binning plays a crucial role in metagenomic data analysis by grouping contigs from the same or closely related genomes. However, existing binning methods face challenges in practical applications due to the diversity of data types and the difficulties in efficiently integrating heterogeneous information. Here, we introduce COMEBin, a binning method based on contrastive multi-view representation learning. COMEBin utilizes data augmentation to generate multiple fragments (views) of each contig and obtains high-quality embeddings of heterogeneous features (sequence coverage and k-mer distribution) through contrastive learning. Experimental results on multiple simulated and real datasets demonstrate that COMEBin outperforms state-of-the-art binning methods, particularly in recovering near-complete genomes from real environmental samples. COMEBin outperforms other binning methods remarkably when integrated into metagenomic analysis pipelines, including the recovery of potentially pathogenic antibiotic-resistant bacteria (PARB) and moderate or higher quality bins containing potential biosynthetic gene clusters (BGCs). Link to OA paper: https://www.nature.com/articles/s41467-023-44290-zhttps://cassyni-user-files-prod.s3.amazonaws.com/TkYwCX39tetMvmr6vzUEzz https://cassyni.com/slides/outline/Nhbt2NoEf9i8vrvuV7cGi1 https://cassyni.com/events/Nhbt2NoEf9i8vrvuV7cGi1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7MVVfjP6rZWm1tZBrGgM3t https://cassyni.com/events/Nhbt2NoEf9i8vrvuV7cGi1?videoPreview=1 Achieving pan-microbiome biological insights via the dbBact knowledge basenohttps://cassyni.com/events/Nhbt2NoEf9i8vrvuV7cGi1?videoPreview=12024-03-20T14:00:00+00:00828.0Microbiome Virtual International Forum Microbiome 16S rRNA studies have examined diverse habitats, including oceans, soil, plants, animals, and large cross-sectional human studies. However, finding commonalities between different experiments, habitats, or conditions is very difficult due to technical issues related to using different primer pairs and relying on taxonomy for scientific reporting. Hence, grosso modo, the 16S rRNA microbiome literature has not been integrated into a collaborative body of knowledge. It often comprises effectively isolated studies, where researchers may be completely unaware of commonalities between their findings and those in other studies, especially across different niches or habitats. In the past five years, we have created dbBact (www.dbbact.org), a knowledge base, to bridge this gap and lay the groundwork for gaining core pan-microbiome insights. Briefly, amplicon sequence variants (ASVs) from datasets of published papers are manually analyzed, and bacterial sequences associated with experimental conditions are uploaded to dbBact, together with ontology-based characterizations (e.g., “the abundance of sequence ACTGGA… was higher in fecal samples of horses with colitis compared to healthy controls in California”). To date, dbBact contains data from more than 1000 published studies across diverse habitats, spanning ~370,000 unique 16S rRNA ASVs, with approximately 1,500,000 sequence-to-phenotype associations. We demonstrated how dbBact provides many types of novel hypotheses that cannot be formulated by standard methods (Amir et al., Nucleic Acids Research, 2023). We will show how dbBact may be (1) applied as part of microbiome research in any niche; (2) allow a new type of meta-analysis; and (3) be harnessed to answer ecological questions. https://cassyni-user-files-prod.s3.amazonaws.com/7MVVfjP6rZWm1tZBrGgM3t https://cassyni.com/slides/outline/Hm7qZYKzGaB7XmDZUduGys https://cassyni.com/events/Hm7qZYKzGaB7XmDZUduGys/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9itP1ZvVsSgkDVpHRmTHqp https://cassyni.com/events/Hm7qZYKzGaB7XmDZUduGys?videoPreview=1 Microbial diversity in aquaculture ecosystems: insights into insect-based feed formulation for sustainable fish farmingnohttps://cassyni.com/events/Hm7qZYKzGaB7XmDZUduGys?videoPreview=12023-11-14T12:00:00+00:00720.04Microbiome Virtual International Forum Aquaculture, an ancient practice deeply rooted in traditional knowledge, has experienced a recent surge in growth, presenting sustainability challenges. Sustainable aquaculture hinges on several factors, including the well-being of farmed fish, water quality, and feeds. A crucial step toward enhancing sustainability in aquaculture is the transition from fishmeal to alternative protein sources. Extensive research has focused on assessing innovative feed formulations, particularly their impact on the fish gut microbiome. However, limited studies have investigated the microbiome of the aquaculture built environment and host-environment microbiome interactions. Here, we explored the aquaculture ecosystem microbiome when insect-based novel feed formulations are administered. Using 16S rRNA gene metabarcoding, we conducted a comprehensive analysis of microbiomes across water, tank biofilm, fish intestinal mucus, fish cutis, and feed samples. Our results showed that overall, water and the aquaculture built environment were characterised by an astounding microbial diversity. Core microbiome analysis unveiled a highly reduced core shared among all sample sources, in both the control and novel feed test groups. Network analysis demonstrated sample clustering based on sample source, with no significant variations tied to the feed formulation. Consequently, the different diets did not appear to impact the environment (water and tank biofilm) and fish (cutis and intestinal mucus) microbiomes. For a more detailed examination of the feed's contribution, we conducted a differential abundance analysis, revealing distinct enrichment/depletion of specific taxa when comparing the control to the insect-based diet group. The results of this study highlight how the aquaculture environment is a unique source of microbes, able to colonise fish. Omic exploration of the water-fish interface exposes patterns that are otherwise undetected: subtle but significant differences in the abundance of specific taxa are exerted by feed. A comprehensive grasp of aquaculture ecosystems as holobiomes is vital to design the built environment and modulate the microbial communities that are hosted for sustainable aquaculture.https://cassyni-user-files-prod.s3.amazonaws.com/9itP1ZvVsSgkDVpHRmTHqp https://cassyni.com/slides/outline/W7KwidW7F21yRSTNSzU181 https://cassyni.com/events/W7KwidW7F21yRSTNSzU181/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JsBud94TRP7BN6h4pCgDzW https://cassyni.com/events/W7KwidW7F21yRSTNSzU181?videoPreview=1 Guts within guts: the microbiome of the intestinal helminth parasite Ascaris suum is derived but distinct from its hostnohttps://cassyni.com/events/W7KwidW7F21yRSTNSzU181?videoPreview=12023-03-14T11:30:00+00:00884.04Microbiome Virtual International Forum Intestinal helminths are extremely prevalent among humans and animals. In particular, intestinal roundworms such as Ascaris suum affect more than 1 billion people around the globe and are a major issue in animal husbandry. These pathogens live in intimate contact with the host gut microbiota and harbor bacteria within their own intestines. Knowledge of the bacterial host microbiome at the site of infection is limited and data on the parasite microbiome is, to the best of our knowledge, non-existent. The intestinal microbiome of Ascaris suum was analyzed in contrast to the diversity and composition of the infected host gut. 16S sequencing of the parasite intestine and host intestinal compartments showed that the parasite gut has a significantly less diverse microbiome than its host and the host gut exhibits a reduced microbiome diversity at the site of parasite infection in the jejunum. While the host’s microbiome composition at the site of infection significantly determines the microbiome composition of its parasite, microbial signatures differentiate the nematodes from their hosts as the Ascaris intestine supports the growth of microbes that are otherwise under-represented in the host gut. Our data clearly indicate that a nematode infection reduces the microbiome diversity of the host gut and that the nematode gut represents a selective bacterial niche harboring bacteria that are derived but distinct from the host gut. Link to OA paper: https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-022-01399-5https://cassyni-user-files-prod.s3.amazonaws.com/JsBud94TRP7BN6h4pCgDzW https://cassyni.com/slides/outline/YaZxx3jjSJnTnNvvzgNdqw https://cassyni.com/events/YaZxx3jjSJnTnNvvzgNdqw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WAGFh2Ek8zbn7pGxdwo2KQ https://cassyni.com/events/YaZxx3jjSJnTnNvvzgNdqw?videoPreview=1 Importance of the nonlinearity in pressure fluctuations for turbulence control and rotor noise perceptionnohttps://cassyni.com/events/YaZxx3jjSJnTnNvvzgNdqw?videoPreview=12023-10-18T11:00:00+00:003415.04Department of Aeronautics and AstronauticsPressure fluctuations, such as those that exist on walls with grazing turbulent boundary layer flows, or those emitted by rotor blades, contain a wealth of information on the flow physics and sound producing mechanisms of such flows. In the first part of this seminar, broadband wall-pressure fluctuations of a turbulent boundary layer are assessed in the framework of an experimental effort of real-time, multi-input/multi-output opposition control, for skin-friction drag reduction. This controller relies on the sensing of the fluctuating wall-pressure, in the estimation of the off-the-wall state of the turbulent velocity fluctuations. To achieve a meaningful control accuracy, nonlinearities in the wall-pressure—velocity coupling must be included. Estimated fluctuating velocity states are then controlled (intensified or attenuated) using wall-normal jet actuators. This presentation will cover aspects of the experimental implementation of the controller, the Reynolds number invariance in the wall-pressure—velocity estimation, and the control performance. In the second part of this seminar, we continue to focus on pressure fluctuations, this time in the context of acoustic footprints of propulsive systems, and we cover the importance of including (nonlinear) frequency interactions in the analyses of pressure imprints in the acoustic near- and far-fields of rotors. Specifically, the time-varying intensity of the higher frequency (broadband) rotor noise content is a nonlinear effect, and this is discussed in terms of its perception, acoustic imprint and aeroacoustic source mechanisms. Note: due to recording issues part of the audio is missing from this presentation. Image credit: [William Warby (Unsplash)](https://unsplash.com/photos/a-close-up-view-of-a-jet-engine-kqAvbh7SdeE).https://cassyni-user-files-prod.s3.amazonaws.com/WAGFh2Ek8zbn7pGxdwo2KQ https://cassyni.com/slides/outline/RAquFo2rrSUx2Lk2SWm1Ps https://cassyni.com/events/RAquFo2rrSUx2Lk2SWm1Ps/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GRM2qr2kf5exCm2vZ2da3Q https://cassyni.com/events/RAquFo2rrSUx2Lk2SWm1Ps?videoPreview=1 An unconditionally-stable well-posed relativistic particle pushernohttps://cassyni.com/events/RAquFo2rrSUx2Lk2SWm1Ps?videoPreview=12024-09-25T12:00:00+00:001182.44Computer Physics CommunicationsParticle pushers widely used in Particle-in-Cell(PIC) simulations are commonly required to be unconditionally stable and meet the basic physical laws. In this work, basing on central difference, we propose an unconditionally stable and well posed particle pusher. By mathematical deduction, the high-dimensional non-linear problem for solving tensor-form relativistic Lorentz force law equation is transformed to a quartic scalar problem and a following linear problem. Some practical suggestions for programming and some numerical results are also given.https://cassyni-user-files-prod.s3.amazonaws.com/GRM2qr2kf5exCm2vZ2da3Q https://cassyni.com/events/Te5vVDGV3jFSPHDazCfe7o/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8gG4wxbBR7qzs9cLkcQL1C https://cassyni.com/events/8NoMgZ31vseZchB64u5LRb/seminar/qa https://cassyni.com/events/8NoMgZ31vseZchB64u5LRb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8myuh2givsmrfSTVMAdKsL https://cassyni.com/slides/outline/X6LvfheJ6KrrdRKMhHYuch https://cassyni.com/events/X6LvfheJ6KrrdRKMhHYuch/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JfHxJ7JnHs8oTXyfvn3dSe https://cassyni.com/events/X6LvfheJ6KrrdRKMhHYuch?videoPreview=1 Nonlinear Dynamics of Soft Actuators: Stiffness of Elastomer-Electrode Interactionsnohttps://cassyni.com/events/X6LvfheJ6KrrdRKMhHYuch?videoPreview=12025-06-24T10:00:00+00:00663.32NODYSDielectric elastomer (DE) has applications in various fields like biomedical, aerospace, pumps, and tactile display. However, its nonlinear characeristics pose as a barrier for its practical applicability. The mathematical models that have been presented till now have not considered the stiffnessof the electrode, generally. However, the electrode’s stiffness does effect the motion of the DE actuator. The mathematical model and nonlinear dynamics of the dielectric elastomer based actuator considering the electrode stiffness is presented in this work. Along with that, the axial effect of the elastomer is also considered to incorporate the dimension of the elastomer. The model is utilized to provide insights into the influence of the electrode and elatomer's geometry on the response of the elastomer. The constant and time-varying voltages are considered to get the static and dynamic behavior of the system. The potential energy behavior and the corresponding equilibrium states of the system is presented. Further, the impact of initial condition, dimension and damping on the equilibrium state achieved for the double-well potential is also described. The influence of shear modulus on the snap-through instability is also examined in this study. Amplitude frequency response is illustrated and the effect of various parameters on it is also analysed. The dynamic response, whether periodic or chaotic, is described and the influence of parameters on it has also been explored. This research helps selecting membrane systems for specific applications by providing a understanding of the factors that influence actuator performance. The study also highlights the importance of dynamic behavior analysis, including the transition between periodic and chaotic responses, which is crucial for designing actuators that can function reliably under different conditions.https://cassyni-user-files-prod.s3.amazonaws.com/JfHxJ7JnHs8oTXyfvn3dSe https://cassyni.com/slides/outline/RfDHABXXGHmnEZ586NZ7dF https://cassyni.com/events/RfDHABXXGHmnEZ586NZ7dF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Ei8k3GeUBZe7dwovCpKXGa https://cassyni.com/events/RfDHABXXGHmnEZ586NZ7dF?videoPreview=1 Dynamics and Chaos Control of a Cournot Game with Heterogeneous Expectations, Asymmetric Information and Social Welfarenohttps://cassyni.com/events/RfDHABXXGHmnEZ586NZ7dF?videoPreview=12025-06-24T10:00:00+00:00674.64NODYSThe present study extends previous works, assumes a Cournot-type duopoly game where the players produce differentiated goods and focus on players with asymmetric information. The players take into account not only their profits, but also a percentage of social welfare which is different for each player. The first player acts like a naïve, while the other as a bounded rational player, who has information about production decision of the other player during the next period. The existence and stability of equilibria of this system is examined. Numerical simulations, through bifurcation diagrams, strange attractors, Lyapunov numbers and sensitive dependence on initial conditions, show the effect of the speed of adjustment of the bounded rational player on the dynamics of the system. The speed of adjustment of the bounded rational player may change the stability of the Nash equilibrium and cause a structure to behave chaotically. After that, is examined the impact of the parameter of degree differentiation of the products in the system. Finally, an attempt is made to control the chaotic behavior.https://cassyni-user-files-prod.s3.amazonaws.com/Ei8k3GeUBZe7dwovCpKXGa https://cassyni.com/slides/outline/6PviMXJ49SAuTy2dB4xow3 https://cassyni.com/events/6PviMXJ49SAuTy2dB4xow3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FpbMPorQAqtLQAivMGyhze https://cassyni.com/events/6PviMXJ49SAuTy2dB4xow3?videoPreview=1 Elastic and Stiffness Tailoring of 3D Dome Structures for Recoverable Energy Dissipation Metamaterialsnohttps://cassyni.com/events/6PviMXJ49SAuTy2dB4xow3?videoPreview=12025-06-24T11:00:00+00:00663.88NODYSNegative stiffness structures enable mechanical metamaterials with recoverable energy dissipation through purely elastic deformation, offering enhanced durability and reusability. While previous studies focused on 2D curved beams, this work investigates 3D axi-symmetric domes, which provide richer buckling modes and greater energy dissipation via multi-directional instability. We develop a framework to optimize dome-shaped negative stiffness elements through elastic tailoring (controlled pre-stressing) and stiffness tailoring (graded thickness and curvature). A nonlinear finite element model captures the effects of geometric nonlinearity, pre-stress, and stiffness gradients, enabling systematic exploration of pre-stressing effects, stiffness gradients, and multi-stable response. A parametric study identifies key design factors, guiding an optimization framework for maximum energy dissipation. Experimental validation demonstrates strong agreement with simulations.https://cassyni-user-files-prod.s3.amazonaws.com/FpbMPorQAqtLQAivMGyhze https://cassyni.com/slides/outline/8sAjawXgLiwPpuWBiksSey https://cassyni.com/events/8sAjawXgLiwPpuWBiksSey/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AkwufoUGfuDLG3T28WsJut https://cassyni.com/events/8sAjawXgLiwPpuWBiksSey?videoPreview=1 Experimental insight into nonlinear dynamics of asymmetric weakly coupled micromachined resonatorsnohttps://cassyni.com/events/8sAjawXgLiwPpuWBiksSey?videoPreview=12025-06-24T11:00:00+00:00613.44NODYSThis work experimentally analyses a novel tunable asymmetric AlN-Piezoelectric weakly coupled resonator consisting of cantilever and bridge resonators. As tuning the applied electrothermal voltage, the system exhibits two veering points and a buckling point, showing great potential for sensing applications. The results demonstrate that the 1st global mode dominated by the cantilever remains unaltered while the 2nd global mode dominated by the bridge varies with increasing electrothermal voltage, proving the great potential for multi-sensing applications. At both veering points, the system energy confinement on bridge-dominated mode and nonlinear mode exchange could be observed. The system nonlinearity changes from highly hardening behaviour to highly softening behaviour at the buckling point where strong harmonic contributions were demonstrated, which could be exploited as a trigger signal in alarming sensor design.https://cassyni-user-files-prod.s3.amazonaws.com/AkwufoUGfuDLG3T28WsJut https://cassyni.com/events/Gma2SWPxmQj48x2AUjr9FB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RRhBkBZeuFs1nYMYWNtCJJ https://cassyni.com/slides/outline/9MqxkFh6BYRYNuqFvaEWo7 https://cassyni.com/events/9MqxkFh6BYRYNuqFvaEWo7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/U9G1Vwd3KGubfCEtDwGpaJ https://cassyni.com/events/9MqxkFh6BYRYNuqFvaEWo7?videoPreview=1 Exploiting novel liquid sheet targets for the generation of bright MeV proton beamsnohttps://cassyni.com/events/9MqxkFh6BYRYNuqFvaEWo7?videoPreview=12024-08-29T15:00:00+00:003046.6Journal of Plasma PhysicsLaser-plasma acceleration has enormous potential to provide compact sources of ultra-short ion beams. However, several factors hamper their wider adoption, such as the low shot-to-shot stability, large beam divergence and the difficulty of high-repetition rate operation. In this talk I will outline an approach for overcoming these challenges by using an automated experimental setup incorporating a novel liquid sheet target, developed by collaborators at the SLAC National Accelerator Laboratory. I will report on recent experiments at the GEMINI TA2 laser facility (10 TW, 5 Hz) which demonstrated stable acceleration of few MeV proton beams with high flux and low-divergence proton beams in comparison to typical laser-accelerated ion beams. Supporting PIC simulations have shown that the presence of background vapour around the target plays an important role in the observed collimation of the proton beam. The measured proton beams are already suitable for applications requiring high proton flux and the platform can be extended to kHz repetition rates or higher laser energies extending the utility of the source to a wide range of applications in radiobiology, materials science and fundamental physics.https://cassyni-user-files-prod.s3.amazonaws.com/U9G1Vwd3KGubfCEtDwGpaJ https://cassyni.com/slides/outline/Bq5yyfviNqC2jrJpUG99X3 https://cassyni.com/events/Bq5yyfviNqC2jrJpUG99X3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Ni8MzRWGVEp9rZtsJD9CLe https://cassyni.com/events/Bq5yyfviNqC2jrJpUG99X3?videoPreview=1 Plasma instabilities and turbulence through a stellarator lensnohttps://cassyni.com/events/Bq5yyfviNqC2jrJpUG99X3?videoPreview=12023-06-01T16:00:00+00:002540.92Journal of Plasma PhysicsHaving non-planar magnetic axis and rotating highly-shaped poloidal cross sections, stellarators are the most complex devices in the family of toroidal chambers used for magnetic confinement fusion. Their complexity, if not dealt with care, can lead to a string of undesirable transport properties such as unsustainable collisional heat losses, hollow density profiles, impurities accumulation, and lack of confinement of trapped and energetic particles. The discovery of stellarator quasi-symmetries, however, opened the way to the solution of the many problems stellarators faced for decades. Today, the stellarator is a viable reactor concept whose potential is constantly reinvigorated by the results of the Wendelstein 7-X (W7-X) experiment, based at Greifswald, Germany. In this talk, we will examine some questions that a modern experiment like W7-X is compelling us to reconsider, and propose the answers to them. Are heat losses turbulent? Which turbulence? How does complex geometry change turbulence? What suppresses or exacerbates this turbulence? How does it saturate? Do electromagnetic fluctuations affect the turbulence saturation process? Do impurities accumulate? Do we observe current-driven magnetic reconnection in a stellarator, even if it was designed to be virtually "current free"? We will close our discussion by summarising the key steps needed to be taken to address the problem of turbulence and stability in high-performance stellarator reactors.https://cassyni-user-files-prod.s3.amazonaws.com/Ni8MzRWGVEp9rZtsJD9CLe https://cassyni.com/slides/outline/QBKiFPcikdxcn1F2jBeKHo https://cassyni.com/events/QBKiFPcikdxcn1F2jBeKHo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GCYe5XQaJcsykpA22coFgJ https://cassyni.com/events/QBKiFPcikdxcn1F2jBeKHo?videoPreview=1 Advances in the understanding of ultrarelativistic beam-plasma instabilitiesnohttps://cassyni.com/events/QBKiFPcikdxcn1F2jBeKHo?videoPreview=12022-10-06T15:00:00+00:003324.44Journal of Plasma PhysicsRelativistic beam-plasma instabilities are thought to arise in many astrophysical systems. One of their major effects is to dissipate into heat, suprathermal particles and radiation the kinetic energy of fast outflows from powerful objects. This occurs via self-induced, kinetic-scale electromagnetic fields that scatter and decelerate particles to the point of forming collisionless shocks waves or triggering bright synchrotron-type emissions. In initially unmagnetized, relativistic beam-plasma systems, two main instability classes are known to prevail: the essentially electrostatic, oblique two-stream modes (OTSI) and the essentially magnetic, transverse current filamentation (CFI) modes. These can also operate, usually detrimentally, in laboratory schemes involving the interpenetration of relativistic electron streams and plasmas, as in plasma-wakefield accelerators or ultraintense laser-solid interactions.https://cassyni-user-files-prod.s3.amazonaws.com/GCYe5XQaJcsykpA22coFgJ https://cassyni.com/events/JkC4jsVwvbsYP8zo8GeXJM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HmeKXb326fH8TUBXHjSCcW https://cassyni.com/events/KEqfnZ9UN4RbNuXgihwKZf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LEtLm1GeHx3fVdRJkXEZci https://cassyni.com/events/VcTMkujVag41uQppjotDFB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/ERxeD3kUhrMtdhHXoTzBeE https://cassyni.com/slides/outline/S9v8S8CpWUBNsiXG69WFiM https://cassyni.com/events/S9v8S8CpWUBNsiXG69WFiM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LrUbkmNiXRfvhkbbrbWuoU https://cassyni.com/events/S9v8S8CpWUBNsiXG69WFiM?videoPreview=1 Turbulence and transport in the Large Plasma Device: shear suppression, nonlinear instability and electromagnetic turbulencenohttps://cassyni.com/events/S9v8S8CpWUBNsiXG69WFiM?videoPreview=12022-01-27T16:00:00+00:003150.08Journal of Plasma PhysicsThe Basic Plasma Science Facility (BaPSF) at UCLA is a US national collaborative research facility for studies of fundamental processes in magnetized plasmas, supported by US DOE and NSF. The centerpiece of the facility is the Large Plasma Device (LAPD), a 20m long, magnetized linear plasma device. LAPD is used to study a number of fundamental processes, including: collisionless shocks, dispersion and damping of kinetic and inertial Alfvén waves, compressional Alfvén waves for ion-cyclotron range of frequencies heating, flux ropes and magnetic reconnection, three-wave interactions and parametric instabilities of Alfvén waves, turbulence and transport and interactions of energetic ions and electrons with plasma waves. An overview of the facility will be given, followed by a more detailed discussion of studies of pressure-gradient-driven turbulence and turbulent transport: suppression of turbulent transport by externally controlled flow and flow shear; simulations of LAPD turbulence that demonstrate the existence and dominance of a nonlinear/non-modal instability; and measurements of electromagnetic drift-wave turbulence, dominated by parallel magnetic field fluctuations, in moderate (~20%) beta plasmas.https://cassyni-user-files-prod.s3.amazonaws.com/LrUbkmNiXRfvhkbbrbWuoU https://cassyni.com/events/UdA9fYSShkwsEezpdqQtSH/abstract https://cassyni.com/events/5QgkVR2n5Ev7jj4yp2aupq/abstract https://cassyni.com/slides/outline/Y5AYpNBH87DkAVpymorBFb https://cassyni.com/events/Y5AYpNBH87DkAVpymorBFb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TE4QXzqrKBagzWsx6RvFzN https://cassyni.com/events/Y5AYpNBH87DkAVpymorBFb?videoPreview=1 Metamaterials for Medical Ultrasoundnohttps://cassyni.com/events/Y5AYpNBH87DkAVpymorBFb?videoPreview=12022-10-25T13:00:00+00:004434.96MetaMATThe development of acoustic metamaterials and the resulted manipulation of ultrasound wave propagation have led to many important technologies that can potentially be applied in medical diagnostics and therapy such as transcranial ultrasound, enhanced cavitation effect for histotripsy and thrombolysis, and noninvasive kidney stone management. In this talk, we will focus on two metamaterial applications in medical imaging and therapy: transcranial imaging enabled by non-Hermitian complementary acoustic metamaterial (NHCMM) and fast sonothrombolysis through vortex ultrasound induced shear stress. High-resolution transcranial imaging using noninvasive high-frequency ultrasound is challenging due to the impedance mismatch between skull and soft tissues and the intrinsic loss because of the porous skull. The development of active NHCMM can compensate the transmission loss resulting from both effects simultaneously that enhances transcranial transmission for high-resolution imaging. For the treatment of blood clots, sonothrombolysis has been demonstrated to be effective. However, the treatment usually last for more than 15 hours when treating large clot, which is undesirable for the patient and surgeon and can sometimes before life threatening for severe cases of cerebral venous sinus thrombosis (CVST). The active metasurface generated vortex ultrasound induces contactless shear stress in the blood clot that drastically enhances fibrinolysis in blood clots that remarkably reduce the required treatment time with low risk of hemorrhage, especially in treating large, completely occluded, acute clots. Such capability makes the vortex ultrasound based endovascular sonothrombolysis a life-saving tool for severe cerebral venous sinus thrombosis, which has an increasing trend among young patients due to the COVID-19 pandemic.https://cassyni-user-files-prod.s3.amazonaws.com/TE4QXzqrKBagzWsx6RvFzN https://cassyni.com/slides/outline/2vwXCfXCdTUbRQpR3Dg421 https://cassyni.com/events/2vwXCfXCdTUbRQpR3Dg421/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TMLD7Aj1zMV2XKmqVZJyxa https://cassyni.com/events/2vwXCfXCdTUbRQpR3Dg421?videoPreview=1 Homogenization and topological optimization for wave propagation in periodic medianohttps://cassyni.com/events/2vwXCfXCdTUbRQpR3Dg421?videoPreview=12023-03-14T14:00:00+00:003943.88MetaMATWe are interested in waves in two-phase periodic materials, either occupying the whole 2D domain, or a thin interface between homogeneous media. The phase distribution in these media is to be optimized to obtain specific dispersive or transmission properties. In these two cases, a first homogenization step is used to describe the effective wave propagation. The two-scale asymptotic homogenization procedure leads to an "enriched" dispersive wave equation in the first case, and effective transmission conditions across an equivalent interface in the second one. In both cases, the effective coefficients of the model are defined through elementary "cell" or "band" problems that we address with FFT-based solvers. A topological optimization procedure is then presented. First, relevant propagation indicators are extracted from the effective models, and serve to define cost functionals to be minimized to achieve certain goals. The sensitivity of the functional to a localized phase change in the representative cell, also called topological derivative (TD), is computed and indicates optimal locations where to perform these phase changes. A TD-based level-set algorithm is finally used to optain optimal microstructures. Applications of the method will finally be presented: maximizing the dispersion in given directions in the full space, or enhancing the transmitted wave in a specific direction. https://cassyni-user-files-prod.s3.amazonaws.com/TMLD7Aj1zMV2XKmqVZJyxa https://cassyni.com/slides/outline/BKM6USBdEJWbKpBJ7sUjXs https://cassyni.com/events/BKM6USBdEJWbKpBJ7sUjXs/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2fQvJoDYDdAqjLP14eTa4E https://cassyni.com/events/BKM6USBdEJWbKpBJ7sUjXs?videoPreview=1 Biophysics in Africa: Breaking barriers in drug discovery: the fusion of atomistic simulation and machine learning in computational biophysicsnohttps://cassyni.com/events/BKM6USBdEJWbKpBJ7sUjXs?videoPreview=12024-03-27T06:00:00+00:003658.04Springer Nature Physics CommunityIn recent years, the field of drug design has undergone a remarkable transformation due to advancements in computer hardware and algorithms. This talk will explore how computational biophysics tools are driving this revolution, ultimately accelerating therapeutic discovery. The presentation will commence with an introduction to various computational biophysics tools utilized in drug design, providing attendees with a comprehensive understanding of the technological landscape shaping the field. Following this, specific examples will be presented to illustrate the profound impact of techniques such as molecular dynamics and enhanced sampling coupled with machine learning in drug design. These examples will highlight the unprecedented insights and efficiencies gained through the integration of computational methods into the drug discovery process. Drawing from my research group experiences, the talk will delve into the entire drug design pipeline, spanning from target identification to lead optimization and clinical trials. Research findings will be shared, elucidating key insights and successes achieved through the application of computational techniques. Lastly, the presentation will conclude with a discussion on the broader societal implications of employing these innovative approaches. By leveraging computational biophysics tools, we have the potential to address pressing societal challenges and advance the development of novel therapeutics, ultimately improving human health and well-being.https://cassyni-user-files-prod.s3.amazonaws.com/2fQvJoDYDdAqjLP14eTa4E https://cassyni.com/slides/outline/EntjutGCoVjV1sLMYiv3Q9 https://cassyni.com/events/EntjutGCoVjV1sLMYiv3Q9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6yjEJKEWJBj6TYXogCjdLa https://cassyni.com/events/EntjutGCoVjV1sLMYiv3Q9?videoPreview=1 Oncology: Emerging Therapeutic Approachesnohttps://cassyni.com/events/EntjutGCoVjV1sLMYiv3Q9?videoPreview=12021-06-24T12:00:00+00:005228.08Research Seminars by Springer NatureThis webinar is the first of a new series that brings together international experts to discuss ongoing developments in cancer research. This webinar focusses on emerging therapeutics, with speakers covering areas including immunotherapy, metabolic targets, and the treatment of lung and colorectal cancers. Our panellists discuss these developments, their ongoing challenges, and their global perspectives.https://cassyni-user-files-prod.s3.amazonaws.com/6yjEJKEWJBj6TYXogCjdLa https://cassyni.com/slides/outline/EJDWka6nxgFfCQLqkco5Dw https://cassyni.com/events/EJDWka6nxgFfCQLqkco5Dw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CiZbMKGXJ4rGoLfWj2FSN https://cassyni.com/events/EJDWka6nxgFfCQLqkco5Dw?videoPreview=1 From 'hysteria' to functional neurological disorder: A sociolinguistic accounting of stigmanohttps://cassyni.com/events/EJDWka6nxgFfCQLqkco5Dw?videoPreview=12022-11-18T03:00:00+00:003174.72Linguistics and Applied Language StudiesPeople with functional neurological disorders (FND) are rendered invisible through stigma surrounding what – and who – is deemed medically ‘worthy’. Accusations of ‘hysteria’ and ‘malingering’ and being told ‘it’s all in your head’ are rooted in ideologies around gender and medical dualisms that contribute to the frequent erasure of FND experiences. A sociolinguistic approach that “walks backward into the future” can shed light on the powerful ways that language maintains this systemic marginalisation, and inform more equitable healthcare. In this seminar, I outline the recent ethnographic phase of my research in the UK and Europe. As well as visiting La Salpêtrière in Paris and exploring the Charcot era (the ‘heyday of hysteria’ in the late 1800s), I spent time with leading neurologists, gender experts, and medical sociologists. I highlight the affordances of this international interdisciplinary approach, and outline the project’s next steps in the Aotearoa context. https://cassyni-user-files-prod.s3.amazonaws.com/CiZbMKGXJ4rGoLfWj2FSN https://cassyni.com/slides/outline/ALfatvE5DKnRuzLt16XnS1 https://cassyni.com/events/ALfatvE5DKnRuzLt16XnS1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/SQoeL8ShzA5pL56TtgiuaW https://cassyni.com/slides/outline/NCCTthEnLx9RJypxGF5p7f https://cassyni.com/events/NCCTthEnLx9RJypxGF5p7f/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2VzP4oSfrKJXLWsbfhNjpA https://cassyni.com/events/NCCTthEnLx9RJypxGF5p7f?videoPreview=1 The Hydrodynamics of Propulsion in Rowingnohttps://cassyni.com/events/NCCTthEnLx9RJypxGF5p7f?videoPreview=12022-05-24T14:00:00+00:002091.52Experiments in FluidsIn order to improve the performance in rowing contests, J. Westerweel et al. built a Ro(w)bot in which they can perform detailed measurements around a 1:2 scale model of an actual rowing blade that moves along a realistic path through water. The set-up allows them to measure both the forces and the impulsive flow by means of time-resolved PIV. They first investigated a more academic case of an accelerating rectangular plate along a straight path, which matches the first stroke at the start of a race. This showed that the forces during the acceleration phase are considerably higher than for steady motion. Also, it demonstrated that there is an optimal depth below the water surface that maximises the drag force. In the second phase of this study they considered the complete motion of an actual rowing blade. This revealed that the generated impulse is not aligned with the propulsive direction, indicating that the propulsion is suboptimal. A simple adjustment is proposed to optimise the alignment of the leading and trailing edge vortices that achieves an improved alignment of the generated impulse with respect to the motion of the boat.https://cassyni-user-files-prod.s3.amazonaws.com/2VzP4oSfrKJXLWsbfhNjpA https://cassyni.com/slides/outline/HFiRRrmXxNcPut7cFmNpPX https://cassyni.com/events/HFiRRrmXxNcPut7cFmNpPX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/E3vboFd7zXWgvDBjD77Su4 https://cassyni.com/events/HFiRRrmXxNcPut7cFmNpPX?videoPreview=1 Direct numerical simulation of the turbulence characteristics in a cylinder wakenohttps://cassyni.com/events/HFiRRrmXxNcPut7cFmNpPX?videoPreview=12022-09-14T10:00:00+00:001510.48NEKTAR++The primary vortex street, turbulent kinetic energy and energy dissipation rate in the wake of a circular cylinder are examined at a Reynolds number of 1000 and up to 120 cylinder diameters downstream of the cylinder. The turbulence characteristics are quantified using direct numerical simulation (based on the framework of Nektar++), which provides a comprehensive dataset that is almost impossible to acquire from physical experiments. The energy dissipation rate is decomposed into the components due to the mean flow, the coherent primary vortices and the remainder. It is found that the remainder component, which develops only in a three-dimensional turbulent wake, accounts for the majority of the total dissipation rate for almost the entire wake. The turbulence dissipation in the wake is largely locally homogeneous, but not locally isotropic or axisymmetric, even after the annihilation of the primary vortex street. The spatial distribution of the turbulence characteristics relative to the spatial distribution of the primary and streamwise vortices is also examined.https://cassyni-user-files-prod.s3.amazonaws.com/E3vboFd7zXWgvDBjD77Su4 https://cassyni.com/slides/outline/KixSfH1A9fNtGpbAoTHT7T https://cassyni.com/events/KixSfH1A9fNtGpbAoTHT7T/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GGDJCWzw7XAmPFbngRqxQE https://cassyni.com/events/KixSfH1A9fNtGpbAoTHT7T?videoPreview=1 Solar water disinfection in resource-poor settings: Why SDG6 is never the sole beneficiarynohttps://cassyni.com/events/KixSfH1A9fNtGpbAoTHT7T?videoPreview=12022-11-22T13:00:00+00:002941.6ElsevierSolar water disinfection (SODIS) is a point-of-use, household water treatment technique for remediating biologically contaminated drinking water in resource-poor-settings such as rural communities in low-to-medium-income countries. In its simplest form, SODIS involves filling transparent containers with available water and placing them in direct sunlight for a minimum of six hours, by which time the microbiological pathogens are inactivated. In this webinar we will look at the science behind this deceptively simple process, how engineered solutions can address obstacles to uptake, and demonstrate how access to safe drinking water contributes not only toward UN Sustainable Development Goal 6 (UNSDG6 Clean Water and Sanitation) but also to many other, perhaps unexpected, SDGs .https://cassyni-user-files-prod.s3.amazonaws.com/GGDJCWzw7XAmPFbngRqxQE https://cassyni.com/events/2SGJ3MMnndzmbwpuF7Z5qo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/T2MrDK2Ct34tqAti7aSLa2 https://cassyni.com/slides/outline/4uWKGmbQyvmFxtJTnoTiZj https://cassyni.com/events/4uWKGmbQyvmFxtJTnoTiZj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/MbEChnuS3zyT2YYhBrJiLN https://cassyni.com/events/4uWKGmbQyvmFxtJTnoTiZj?videoPreview=1 Dynamo Generating Flows in Planetary Coresnohttps://cassyni.com/events/4uWKGmbQyvmFxtJTnoTiZj?videoPreview=12021-03-19T16:00:00+00:004460.0Journal of Fluid MechanicsPlanetary bodies typically host substantial liquid metal interior fluid layers. The fluid layers are often in turbulent motion due to planetary thermochemical evolutionary processes. This rapidly rotating turbulence can generate coherent, planetary-scale magnetic fields that can protectively shield a planet for its harsh surrounding space environment. In this talk, I will present scaling arguments for the behaviors of core flows mixed with simple table-top experiments. I will then present the most recent laboratory and theoretical models of these flows, and what aspects of dynamo observations they can and cannot yet explain.https://cassyni-user-files-prod.s3.amazonaws.com/MbEChnuS3zyT2YYhBrJiLN https://cassyni.com/slides/outline/DJXb4PbLSiBF8Devrenmnd https://cassyni.com/events/DJXb4PbLSiBF8Devrenmnd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2J3afr4tcwiKeUYeenNhv6 https://cassyni.com/events/DJXb4PbLSiBF8Devrenmnd?videoPreview=1 Wavefront shaping for Wireless Communications in complex media with tunable metasurfacesnohttps://cassyni.com/events/DJXb4PbLSiBF8Devrenmnd?videoPreview=12022-07-04T14:20:00+00:002366.04ETOPIMIn this talk, I will show how the work performed at Langevin Institute on wave control have led to the seminal concept behind large reconfigurable intelligent surfaces (RIS) that is currently a topic of great interest in the wireless communication community and that is proposed as a new paradigm for the sixth generation (6G) of communication networks. Starting with the first demonstrations of “time-reversal mirrors” that are connected to the concept of active focusing with multiple antenna (MIMO communications), I will compare this classical approach to a new approach using tunable metasurfaces to obtain the best communication performance. The main idea is to replace the numerous transmitting antennas in MIMO communications by a smart modification of the wireless environment by physically shaping the propagation medium to achieve optimal focusing and channel diversity. I will show how the optimization of these metasurfaces results from the generalization of the “time reversal mirror” concept to the one of the products of different time-reversal mirrors associated with each transmitter and receiver. I will discuss the way to simplify these reconfigurable metasurfaces to increase significantly the Shannon capacity et the energy efficiency in complex environment.https://cassyni-user-files-prod.s3.amazonaws.com/2J3afr4tcwiKeUYeenNhv6 https://cassyni.com/slides/outline/FmmcHopxdzwjVA8VQLhQWZ https://cassyni.com/events/FmmcHopxdzwjVA8VQLhQWZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7UrRf2MuEFXJXdP75ptWMU https://cassyni.com/events/FmmcHopxdzwjVA8VQLhQWZ?videoPreview=1 Active mechanical metamaterials: from wave guiding to roboticsnohttps://cassyni.com/events/FmmcHopxdzwjVA8VQLhQWZ?videoPreview=12022-07-06T07:00:00+00:001734.04ETOPIMControlling how waves propagate, attenuate and amplify in simple, scalable geometric structures is a daunting challenge for science and technology. In this talk, I will discuss how odd matter—in which microscopic interactions are asymmetric and non-conservative—can be used to steer mechanical waves in unprecedented ways. Combining experiments active mechanical metamaterials with wave physics and continuum and topological mechanics, I will discuss the emergence of the non-Hermitian skin effect, of non-Hermitian topological waves and of one-way solitons. I will further show how these odd waves can be used to induce locomotion and unusual responses to impacts and hence pave the way towards a novel generation of robots.https://cassyni-user-files-prod.s3.amazonaws.com/7UrRf2MuEFXJXdP75ptWMU https://cassyni.com/slides/outline/CKENy2JHZo56TTpvkgKSyj https://cassyni.com/events/CKENy2JHZo56TTpvkgKSyj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/YR1N6KiHwJ2PxshfVKAtgN https://cassyni.com/events/CKENy2JHZo56TTpvkgKSyj?videoPreview=1 Speckle statistics in space and time-disordered medianohttps://cassyni.com/events/CKENy2JHZo56TTpvkgKSyj?videoPreview=12022-07-08T06:00:00+00:002982.04ETOPIMThis talk will concentrate upon model elastic, mechanical and acoustic devices that have resonance as a key component and where grading or otherwise altering a parameter lead to interesting and useful effects. This includes focussing and redirecting wave energy. To further illustrate the control that it is possible to have over elastic waves and vibration an elastic orbital angular momentum device will be discussed that converts one wave mode into another.https://cassyni-user-files-prod.s3.amazonaws.com/YR1N6KiHwJ2PxshfVKAtgN https://cassyni.com/slides/outline/Ngsh41QCBmdF8SpU4MCnHs https://cassyni.com/events/Ngsh41QCBmdF8SpU4MCnHs/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7NMsd81E6SBNEtpubui8UW https://cassyni.com/events/Ngsh41QCBmdF8SpU4MCnHs?videoPreview=1 Anomalies in Physical Cosmologynohttps://cassyni.com/events/Ngsh41QCBmdF8SpU4MCnHs?videoPreview=12022-12-05T15:00:00+00:003553.88Annals of PhysicsThe ΛCDM cosmology passes demanding tests that establish it as a good approximation to reality. The theory is incomplete, of course, and open issues are being examined in research programs that promise to improve the cosmological tests and perhaps yield hints to a still better theory. But there is the possibility that less widely discussed observations, if more thoroughly explored, will aid the search for a better theory. I propose to discuss examples. https://cassyni-user-files-prod.s3.amazonaws.com/7NMsd81E6SBNEtpubui8UW https://cassyni.com/slides/outline/PBXJ6h3idEBJ8DMMenVaZB https://cassyni.com/events/PBXJ6h3idEBJ8DMMenVaZB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PSfDdMaehU3pJFQN6cjgsp https://cassyni.com/events/PBXJ6h3idEBJ8DMMenVaZB?videoPreview=1 Time-dependent accretion discs around Kerr black holes and tidal disruption eventsnohttps://cassyni.com/events/PBXJ6h3idEBJ8DMMenVaZB?videoPreview=12020-11-13T16:00:00+00:004580.64Journal of Fluid MechanicsThe theory of Newtonian astrophysical accretion discs, both in its steady and time-dependent form, dates from the mid-1970s. Relativistic thin disc theory was developed at nearly the same time, but only for steady-state conditions. I will present recent work on the fluid dynamics of time-dependent accretion discs around Kerr black holes. This work has a natural application to so-called tidal disruption events (TDEs), the tidal break-up of star when it passes too close to a galaxy's central black hole. The stellar debris collects into a disc, whose inner boundary corresponds to a radius at which the Rayleigh criterion for rotational stability is violated according to general relativity. This requires some care in its treatment, particularly with regard to the inner stress, since both the interpretation of astronomical observations and numerical simulations depend upon a detailed understanding of this innermost stable circular orbit. TDEs generally exhibit a slowly decreasing light curve that is not at present well-understood. It is, however, quite consistent with an extended evolutionary phase of time-dependent relativistic disc theory. The interplay between mathematics, fluid theory, and astrophysics is particularly striking for these objects.https://cassyni-user-files-prod.s3.amazonaws.com/PSfDdMaehU3pJFQN6cjgsp https://cassyni.com/slides/outline/HkPebAvwoC6DjM783sVnZj https://cassyni.com/events/HkPebAvwoC6DjM783sVnZj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4P7ijCbJsVKWqPrjJtW8QN https://cassyni.com/events/HkPebAvwoC6DjM783sVnZj?videoPreview=1 Eigenvector Pagerank difference as a measure to reveal topological characteristics of the brain connectome for neurosurgerynohttps://cassyni.com/events/HkPebAvwoC6DjM783sVnZj?videoPreview=12022-11-07T16:00:00+00:001813.52Journal of Neuro-OncologyNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/4P7ijCbJsVKWqPrjJtW8QN https://cassyni.com/slides/outline/YZqmygLgxvhZyxpVZuy9Ro https://cassyni.com/events/YZqmygLgxvhZyxpVZuy9Ro/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DBFxRmjJveSufV3udBZaXG https://cassyni.com/events/YZqmygLgxvhZyxpVZuy9Ro?videoPreview=1 Using the Force/Moment Partitioning Method on Experimental Datanohttps://cassyni.com/events/YZqmygLgxvhZyxpVZuy9Ro?videoPreview=12023-03-07T15:00:00+00:003471.16Experiments in FluidsUsing PIV data to determine forces and moments on a solid body in a flow is notoriously difficult. Here we apply and assess the performance of the Force and Moment Partitioning Method (FMPM, Menon and Mittal JCP 2021). The FMPM combines the measured velocity field with an analytically derived "influence potential" to create an "influence field" which describes the contribution to the forces and moments from every point in the spatial domian. Integrating the influence field yields the total forces and moments acting on the body. The techinique is particularly powerful when applied to High Reynolds number flows which are dominated by large vortical structures. We will apply the FMPM to flows around a pitching wing under a range of operating conditions, and assess the particular challenges associated with applying the FMPM to experimental data, its successes and limitations.https://cassyni-user-files-prod.s3.amazonaws.com/DBFxRmjJveSufV3udBZaXG https://cassyni.com/slides/outline/RA7iHRdpP4Q4Dvdb1kMWyj https://cassyni.com/events/RA7iHRdpP4Q4Dvdb1kMWyj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7iXqsf8EiwY54W35haKfiW https://cassyni.com/events/RA7iHRdpP4Q4Dvdb1kMWyj?videoPreview=1 Dynamics of Marine Ice Sheetsnohttps://cassyni.com/events/RA7iHRdpP4Q4Dvdb1kMWyj?videoPreview=12019-02-15T13:00:00+00:002966.16UK Fluids NetworkOn short length and time scales, ice behaves as a brittle, elastic solid but on continental length scales and timescales of years or longer, ice flows as a viscous fluid. The West Antarctic Ice Sheet, for example, sits on bedrock that is 1–2 kilometres below sea level. The ice itself is 4–5 kilometres thick in the central regions but thins as it flows towards the margins and eventually becomes thin enough to float on the ocean as a so-called ice shelf. The locus of detachment from the bedrock, where the ice sheet first starts to float, is called the grounding line. The position of the grounding line is determined dynamically, and there is concern to understand the conditions under which the grounding line would recede and allow the ice sheet to flow ever faster into the ocean, causing global sea levels to rise. I will present some simple fluid-mechanical experiments and mathematical models to address some of the fundamental physical balances that control the stability of grounding lines.https://cassyni-user-files-prod.s3.amazonaws.com/7iXqsf8EiwY54W35haKfiW https://cassyni.com/slides/outline/TdMjWqsSaMAYas79ZSG9hf https://cassyni.com/events/TdMjWqsSaMAYas79ZSG9hf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/U4KSQ7DQHJ2QpTsNBvaKcr https://cassyni.com/events/TdMjWqsSaMAYas79ZSG9hf?videoPreview=1 Stochastic Flows and Rough Differential Equations on Foliated Spacesnohttps://cassyni.com/events/TdMjWqsSaMAYas79ZSG9hf?videoPreview=12021-09-22T09:00:00+00:002405.04DataSıgStochastic differential equations (SDEs) on compact foliated spaces were introduced a few years ago. As a corollary, a leafwise Brownian motion on a compact foliated space was obtained as a solution to an SDE. In this work we construct stochastic flows associated with the SDEs by using rough path theory, which is something like a 'deterministic version' of Ito's SDE theory.https://cassyni-user-files-prod.s3.amazonaws.com/U4KSQ7DQHJ2QpTsNBvaKcr https://cassyni.com/slides/outline/MCxW2ayWGktdajsJuChv1T https://cassyni.com/events/MCxW2ayWGktdajsJuChv1T/abstract https://cassyni-user-files-prod.s3.amazonaws.com/L6AvBR82i8N9LVkk9UJXQ https://cassyni.com/events/MCxW2ayWGktdajsJuChv1T?videoPreview=1 Protective Nanocoatings from Polyelectrolytes: Flame Retardancy, Super Gas Barrier, and Heat Shieldingnohttps://cassyni.com/events/MCxW2ayWGktdajsJuChv1T?videoPreview=12023-02-20T13:00:00+00:003869.88Department of AeronauticsLayer-by-layer (LbL) assembly is a conformal coating “platform” technology capable of imparting a multiplicity of functionalities on nearly any type of surface in a relatively environmentally friendly way. At its core, LbL is a solution deposition technique in which layers of cationic and anionic materials (e.g. nanoparticles, polymers and even biological molecules) are built up via electrostatic attractions in an alternating fashion, while controlling process variables such as pH, coating time, and concentration. Here we are producing nanocomposite multilayers (50 – 1000 nm thick), having 10 – 96 wt% clay, that can be completely transparent, stop gas permeation, and impart extreme heat shielding to polymeric substrates. In an effort to impart flame retardant behavior to fabric using fewer processing steps, a water-soluble polyelectrolyte complex (PEC) was developed. This nanocoating is comprised of polyethylenimine and poly(sodium phosphate) and imparts self-extinguishing behavior to cotton fabric in just a single coating step. Adding a melamine solution to the coating procedure as a second step renders nylon-cotton blends self-extinguishing. More recently, a PEC coating was developed for polyester-cotton. It passes vertical flame testing after five standard washes or 8 hours in boiling water. Either of these two coating techniques can be deposited using flexographic printing or spray-coating tools. Opportunities and challenges will be discussed. Our work in these areas has been highlighted in C&EN, ScienceNews, Nature, Smithsonian Magazine, Chemistry World and various scientific news outlets worldwide. For more information, please visit my website: <http://nanocomposites.tamu.edu>https://cassyni-user-files-prod.s3.amazonaws.com/L6AvBR82i8N9LVkk9UJXQ https://cassyni.com/events/T9QhKu75CumcZpE5C6Yfwb/seminar/qa https://cassyni.com/slides/outline/T9QhKu75CumcZpE5C6Yfwb https://cassyni.com/events/T9QhKu75CumcZpE5C6Yfwb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/F5coNMocekejianqSTU3dx https://cassyni.com/events/T9QhKu75CumcZpE5C6Yfwb?videoPreview=1 Predicting the impact of climate change on tick populations- a dynamic GIS approachnohttps://cassyni.com/events/T9QhKu75CumcZpE5C6Yfwb?videoPreview=12024-11-01T11:00:00+00:003570.56Royal Society PublishingMechanistic mathematical models such as ordinary differential equations (ODEs) have a long history for their use in describing population dynamics and determining estimates of key parameters that summarize the potential growth or decline of a population over time. More recently, geographic information systems (GIS) have become important tools to provide a visual representation of statistically determined parameters and environmental features over space. Here, we combine these tools to form a ‘GIS-ODE’ approach to generate spatiotemporal maps predicting how projected changes in thermal climate may affect population densities and, uniquely, population dynamics of Ixodes ricinus, an important tick vector of several human pathogens. Assuming habitat and host densities are not greatly affected by climate warming, the GIS-ODE model predicted that, even under the lowest projected temperature increase, I. ricinus nymph densities could increase by 26–99% in Scotland, depending on the habitat and climate of the location. Our GIS-ODE model provides the vector-borne disease research community with a framework option to produce predictive, spatially explicit risk maps based on a mechanistic understanding of vector and vector-borne disease transmission dynamics.https://cassyni-user-files-prod.s3.amazonaws.com/F5coNMocekejianqSTU3dx https://cassyni.com/events/2wfiB2vF6qZVDpvrTz5YS9/seminar/qa https://cassyni.com/slides/outline/2wfiB2vF6qZVDpvrTz5YS9 https://cassyni.com/events/2wfiB2vF6qZVDpvrTz5YS9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3kTLYxHrAhJJeuGCxzp3pi https://cassyni.com/events/2wfiB2vF6qZVDpvrTz5YS9?videoPreview=1 Metamaterials for controlling fluid-flow turbulence and elastic wave steeringnohttps://cassyni.com/events/2wfiB2vF6qZVDpvrTz5YS9?videoPreview=12024-11-19T14:00:00+00:004140.04MetaMATMetamaterials capable of manipulating dynamic characteristics of fluids and solids reveal more and more advanced performance steadily expanding the traditional bounds on material properties and functionalities are applied in an increasing range of research and engineering areas and. In this talk, we discuss the applications of mechanical metamaterials to reduce turbulence in high-speed fluid flows in pipes and present the design strategy for rationally-pruned disordered networks to achieve frequency-driven wave steering. For fluid flow in pipes, we extend of the Darcy-Forchheimer model for low Reynolds numbers to a turbulent regime for a flow through triply periodic minimal surface inserts. For disordered lattice-type networks, we analyze the possibility of elastic wave steering without discernible paths connecting an input and output by using the excitation frequency as a natural control parameter. The obtained rationally pruned meta-designs are converted into continuum analogues and their frequency-driven wave-steering functionality is validated numerically and experimentally.https://cassyni-user-files-prod.s3.amazonaws.com/3kTLYxHrAhJJeuGCxzp3pi https://cassyni.com/events/3SKKDiZmYJ7YDbTk4RNLhT/seminar/qa https://cassyni.com/slides/outline/3SKKDiZmYJ7YDbTk4RNLhT https://cassyni.com/events/3SKKDiZmYJ7YDbTk4RNLhT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TFiM3UJske6nAogFpnV71x https://cassyni.com/events/3SKKDiZmYJ7YDbTk4RNLhT?videoPreview=1 Glide-reflection symmetric phononic crystal interfaces and resonator chainsnohttps://cassyni.com/events/3SKKDiZmYJ7YDbTk4RNLhT?videoPreview=12024-12-10T14:00:00+00:003785.04MetaMATPeriodic structures, including metamaterial networks and phononic crystal waveguides, can jump between different space symmetry classes during a continuous deformation. Recently, it was shown that such a deformation that encircles a configuration of an array of cavity resonators results in an adiabatic cycle that carries a Chern number in the bulk and displays Thouless pumping at the edges, implying the existence of a topological charge. Similarly, when a glide-symmetric dislocation is introduced in a 2D phononic crystal, symmetry-protected guided waves appear in the bulk band gap. Continuous grading of the unit cell of the crstal was further shown to leave the band structure mostly unaffected. This suggests that topological interface waves survive in the case that glide-reflection symmetry is only locally valid around the graded interface and points at their robustness to continuous deformations of the crystal lattice.https://cassyni-user-files-prod.s3.amazonaws.com/TFiM3UJske6nAogFpnV71x https://cassyni.com/events/AMPmsHd7ghsKiQTKRrwGr9/seminar/qa https://cassyni.com/slides/outline/AMPmsHd7ghsKiQTKRrwGr9 https://cassyni.com/events/AMPmsHd7ghsKiQTKRrwGr9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VAvKtBjg5hntmjtjVk8jBk https://cassyni.com/events/AMPmsHd7ghsKiQTKRrwGr9?videoPreview=1 Ensuring Equity in Open Accessnohttps://cassyni.com/events/AMPmsHd7ghsKiQTKRrwGr9?videoPreview=12024-10-23T14:00:00+00:003361.92Topics at the heart of our communityIn the transition towards open access (OA), commitment to equity and accessibility is key to ensuring global participation and representation are included in OA strategies. While there are still central challenges to bridging these gaps in OA, there are several ways these barriers are increasingly being broken. Join Caroline Nevison, Director of Open Access Agreements at Springer Nature, in conversation with Sarah Phibbs, Director of Research4Life Publisher Partnerships at STM, to discuss the progress towards providing OA opportunities more broadly in research.https://cassyni-user-files-prod.s3.amazonaws.com/VAvKtBjg5hntmjtjVk8jBk https://cassyni.com/events/X6emvdK3XJ3rEyZcoNV6nh/seminar/qa https://cassyni.com/slides/outline/X6emvdK3XJ3rEyZcoNV6nh https://cassyni.com/events/X6emvdK3XJ3rEyZcoNV6nh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9H6cjtKC7SQ7oXtzcoVVNE https://cassyni.com/events/X6emvdK3XJ3rEyZcoNV6nh?videoPreview=1 The Geometry of Phenotypes: what can cell morphology tell us about cell state?nohttps://cassyni.com/events/X6emvdK3XJ3rEyZcoNV6nh?videoPreview=12024-10-24T14:00:00+00:004365.2Journal of Biological PhysicsThe cellular cytoskeleton is a dynamic non-equilibrium filamentous polymer network that determines cell shape and is crucially important for many physiological functions, from intracellular transport to cell division. Given this, many changes in cell state should be reflected in changes in cell shape and cytoskeletal organization. In this talk I describe our recent investigations exploring this hypothesis. We imaged thousands of cells in different experimental conditions and used many morphological parameters to measure cell shape and cytoskeletal morphology. Using machine learning methods, we show that quantifiers of cell shape and cytoskeletal texture can be used to distinguish between cancer cells that differ by a single inserted gene mutation. Pharmacological drugs that perturb the cytoskeleton can also be identified by morphological changes. Interpretable machine learning methods indicate that classification accuracy is driven by subtle localized features of actin structure. Furthermore, using data-driven models we also uncovered interlinkages between cell shape, actin cytoskeleton organization and nuclear shape. Our results suggest that morphological features of cells possess untapped information about cell states. https://cassyni-user-files-prod.s3.amazonaws.com/9H6cjtKC7SQ7oXtzcoVVNE https://cassyni.com/events/6QEZcSxoaQMu5XGtH9u173/seminar/qa https://cassyni.com/slides/outline/6QEZcSxoaQMu5XGtH9u173 https://cassyni.com/events/6QEZcSxoaQMu5XGtH9u173/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7UMQG3zGiWEAifkBcDjqHG https://cassyni.com/events/6QEZcSxoaQMu5XGtH9u173?videoPreview=1 Presentation of EAJ Issues 14/3 - November 19thnohttps://cassyni.com/events/6QEZcSxoaQMu5XGtH9u173?videoPreview=12024-11-19T16:00:00+00:003880.52European Actuarial JournalThe seminar will be opened by Stephane Loisel and closed by Hansjoerg Albrecher.https://cassyni-user-files-prod.s3.amazonaws.com/7UMQG3zGiWEAifkBcDjqHG https://cassyni.com/slides/outline/Dow1C59nkujxk6kt5XKENy https://cassyni.com/events/Dow1C59nkujxk6kt5XKENy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Vt6w5Vzg8bJdjPt8Vm8R3t https://cassyni.com/slides/outline/PgviENcAwRk1kQ39qVdNNh https://cassyni.com/events/PgviENcAwRk1kQ39qVdNNh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LoxnLQE6tYf1kNCzHqzVmG https://cassyni.com/events/PgviENcAwRk1kQ39qVdNNh?videoPreview=1 How Natural Disasters Affect Women and Girls in the Global Southnohttps://cassyni.com/events/PgviENcAwRk1kQ39qVdNNh?videoPreview=12024-06-25T14:00:00+00:001808.48Springer Nature Sustainable Development Goals ProgrammeWomen and girls in the Global South are impacted disproportionately by climate change and natural disasters because they face heightened risks in society due to social norms and inequalities. Despite often being the hardest hit, they are frequently excluded from decision-making, leaving them more vulnerable. Yet, they possess incredible resilience and the capacity to lead environmental preservation efforts. Understanding the challenges they face and including the voices of women and girls is essential for developing targeted and tailored interventions that reduce the impact of natural disruptions on women and girls, and ensuring their safety and well-being. This panel discussion explores these issues and highlights best practice in designing gender responsive disaster risk reduction strategies and policies.https://cassyni-user-files-prod.s3.amazonaws.com/LoxnLQE6tYf1kNCzHqzVmG https://cassyni.com/slides/outline/JFpgqV1HWkaiBEFYSFTkJ9 https://cassyni.com/events/JFpgqV1HWkaiBEFYSFTkJ9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/98B2UzGJWBsrXR22U1aQWA https://cassyni.com/events/JFpgqV1HWkaiBEFYSFTkJ9?videoPreview=1 The future of evolutionary medicinenohttps://cassyni.com/events/JFpgqV1HWkaiBEFYSFTkJ9?videoPreview=12023-09-21T14:00:00+00:005334.8Frontiers in ScienceEvolutionary processes drive many health threats, from antimicrobial resistance to pandemics to ‘Anthropocene-related’ conditions such as obesity. Could evolution also inspire new ways to prevent and treat disease? In this Frontiers Forum Deep Dive session on 21 September 2023, Professors Barbara Natterson-Horowitz, Dan Blumstein, Randolph Nesse, and other renowned researchers, examined how evolutionary medicine can help inspire new ways to prevent and treat disease. The session brought together the authors of the Frontiers in Science lead article ‘The future of evolutionary medicine: sparking innovation in biomedicine and public health’ in which they propose an interdisciplinary research agenda to realize the untapped potential of evolutionary medicine for addressing the critical health challenges of the 21st century. https://cassyni-user-files-prod.s3.amazonaws.com/98B2UzGJWBsrXR22U1aQWA https://cassyni.com/slides/outline/Lj4i4uEui3MCYAj6ywNP25 https://cassyni.com/events/Lj4i4uEui3MCYAj6ywNP25/abstract https://cassyni-user-files-prod.s3.amazonaws.com/MgwiL5X9y77xSXSJKi1gCN https://cassyni.com/events/Lj4i4uEui3MCYAj6ywNP25?videoPreview=1 Activation of orexin-A (hypocretin-1) receptors in the Raphe Pallidus at different ambient temperatures in the rat: effects on thermoregulation, cardiovascular control, sleep, and feeding behaviornohttps://cassyni.com/events/Lj4i4uEui3MCYAj6ywNP25?videoPreview=12024-12-10T08:00:00+00:002283.84Frontiers in NeuroscienceThe Raphe Pallidus (RPa) is a brainstem nucleus containing sympathetic premotor neurons that control thermogenesis and modulate cardiovascular function. It receives inputs from various hypothalamic areas, including the Lateral Hypothalamus (LH), a heterogeneous region intricately involved in several autonomic and behavioral functions. A key subpopulation of neurons in the LH expresses orexin/hypocretin, a neuropeptide which is crucially involved in the regulation of the wake–sleep states and feeding behavior. The RPa receives orexinergic projections from the LH and orexinergic signalling in the RPa has been shown to enhance thermogenesis in the anaesthetized rat, but only in the presence of an already existing thermogenic drive, without significantly affecting cardiovascular function. The present work was aimed at exploring the effects on thermoregulation and autonomic function and the possible role in the modulation of the wake–sleep states and feeding behavior of orexin injection in the RPa in the free-behaving rat. In order to assess the influence of an already present thermogenic drive on orexinergic signalling in the RPa, animals were studied at three different ambient temperatures (Ta, 10°C, 24°C, and 32°C). We found that orexin injection into the RPa variably affected the wake–sleep states, autonomic functions, motor activity, and feeding behavior, at the different Tas. In particular, in the first post-injection hour, we observed an increase in wakefulness, which was large at Ta 24°C and Ta 10°C and rather mild at Ta 32°C. Deep brain temperature was increased by orexin injection at Ta 10°C, but not at either Ta 24°C or Ta 32°C. Moreover, an increase in mean arterial blood pressure occurred at Ta 24°C, which was probably masked by the high baseline levels at Ta 10°C and was completely absent at Ta 32°C. Finally, an enhancement in feeding behavior was observed at Ta 24°C and 10°C only. In accordance with what observed in anaesthetized rats, orexinergic signalling in the RPa seems to be ineffective in the absence of any thermogenic drive. Moreover, the effects observed on the wake–sleep states and feeding behavior introduce the RPa as a novel player in the central neural network promoting wakefulness and feeding.https://cassyni-user-files-prod.s3.amazonaws.com/MgwiL5X9y77xSXSJKi1gCN https://cassyni.com/events/U8nmm9wnHuf32kFZwpE7S5/seminar/qa https://cassyni.com/slides/outline/U8nmm9wnHuf32kFZwpE7S5 https://cassyni.com/events/U8nmm9wnHuf32kFZwpE7S5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4cDuos7oV8KRmutRX9S1up https://cassyni.com/events/KF9X3UpDo2cazTmwpnsWjf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UXdJnKRgtp1nqsGNBGxQNS https://cassyni.com/events/VcmD1qQF1eF1Wy55qtpQRB/seminar/qa https://cassyni.com/slides/outline/VcmD1qQF1eF1Wy55qtpQRB https://cassyni.com/events/VcmD1qQF1eF1Wy55qtpQRB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WsCFVM8xvAH8YnsK4A7VNE https://cassyni.com/events/VcmD1qQF1eF1Wy55qtpQRB?videoPreview=1 clocks replaced with : ; . [Deschooling Time in the Small Isles]nohttps://cassyni.com/events/VcmD1qQF1eF1Wy55qtpQRB?videoPreview=12025-05-07T13:00:00+00:001993.48Cambridge PrismsIn July 2023, the poet and editor Kate Simpson visited the Scottish Small Isles, geologically complex landscapes featuring samples from the Archean (Lewisian gneiss basements formed approximately three billion years ago), Proterozoic (Torridonian sandstone formed approximately one billion years ago), Mesozoic (sedimentation deposited approximately 200 million years ago, and Palaeocene (basalt formed approximately 55.8 million years ago as part of the Paleocene-Eocene Thermal Maximum event). Writing in-situ, she documented her experiences interacting, writing, and thinking with the remnants of multiple eras, her notion of temporality being “deschooled” and destabilised by lithic time. In this seminar, framed as performance, she will share the results of her exploratory practice, reading from a text that has been consciously “made of time”, blending the domains of past, present, and future, in both form and content.https://cassyni-user-files-prod.s3.amazonaws.com/WsCFVM8xvAH8YnsK4A7VNE https://cassyni.com/events/UdTzvU7C8j8rrDF5jvM5cH/seminar/qa https://cassyni.com/slides/outline/UdTzvU7C8j8rrDF5jvM5cH https://cassyni.com/events/UdTzvU7C8j8rrDF5jvM5cH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/X7X41gxj8tZBPHWsJvhke2 https://cassyni.com/events/UdTzvU7C8j8rrDF5jvM5cH?videoPreview=1 Low cost, high throughput quantification of microplastics released from textile wash tests: Introducing the fibre fragmentation scalenohttps://cassyni.com/events/UdTzvU7C8j8rrDF5jvM5cH?videoPreview=12025-07-02T13:00:00+00:001649.24Cambridge PrismsMicroplastic fibres are found everywhere that researchers have looked for them, from remote mountains to human lungs. However, data is not yet available to facilitate design of low-shedding textiles. Effective use of standard test methods could establish the impact of processing variables on textile’s propensity to fragment or shed fibres into the environment, allowing industry to design and select lower-polluting materials. Three new test methods recommend using the widely accessible accelerated laundering equipment used for colour fastness to wash tests. However, recommended gravimetric analysis of results takes over 8 hours per specimen batch, in addition to specimen preparation, testing and effluent filtration, making analysing test results prohibitively time consuming, and expensive, for many brands. Visual ‘grey scales’ are very commonly used to grade colour fastness test results and this paper proposes use of an equivalent ‘fibre fragmentation scale’ to dramatically increase the throughput of fibre fragmentation testing and reduce its cost without compromising accuracy or reliability. Mean fibre fragmentation scale grades given by sets of 3 observers correlated with gravimetric results at 99% confidence. Subjective grades assigned to test specimens, and photographs of test specimens, had significantly lower variability than gravimetric methods at small, ‘more acceptable’, levels of fibre fragmentation.https://cassyni-user-files-prod.s3.amazonaws.com/X7X41gxj8tZBPHWsJvhke2 https://cassyni.com/slides/outline/XbL15wUTN7Xg4SZ8bUc4xu https://cassyni.com/events/XbL15wUTN7Xg4SZ8bUc4xu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7p1PbsuDGgRUCdDipYYhCS https://cassyni.com/events/XbL15wUTN7Xg4SZ8bUc4xu?videoPreview=1 The Impact of The Defunding of DEI Initiatives & The Social Justice Uprising on Black Women-Owned Businessesnohttps://cassyni.com/events/XbL15wUTN7Xg4SZ8bUc4xu?videoPreview=12024-11-20T15:00:00+00:00654.28Center for Black Entrepreneurship, Spelman College**Background:** Black Women Business Owners (BWBOs) faced compounded challenges during the COVID-19 pandemic and the social justice uprising, which highlighted pre-existing inequalities and led to increased support for Black businesses; followed by the defunding of DEI initiatives and the waning of public support for Black businesses, which further affected these business owners. **Aims:** To understand the specific obstacles BWBOs have and are facing, and the implications for Black entrepreneurship. **Methods:** A mixed methods approach, integrating a quantitative survey, qualitative interviews and roundtable discussions to gather primary data. The survey was administered to 199 BWBOs, 20 entrepreneurs participated in the roundtables and four Black Women were interviewed. Descriptive statistics were used to summarize the survey data, inferential statistics were applied to examine the relationships between DEI support and business outcomes, and transcripts from interviews and roundtable discussions were analyzed using thematic analysis to identify common themes and narratives. **Disclosure:** This study was supported by Bloomberg Philanthropies, the Center for Black Entrepreneurship and the Black Economic Alliance Foundation.https://cassyni-user-files-prod.s3.amazonaws.com/7p1PbsuDGgRUCdDipYYhCS https://cassyni.com/events/xRkJvey2eJhVtZ44nJyZ7/seminar/qa https://cassyni.com/slides/outline/xRkJvey2eJhVtZ44nJyZ7 https://cassyni.com/events/xRkJvey2eJhVtZ44nJyZ7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DnV2nq3bso6B9xchJLPsuG https://cassyni.com/events/xRkJvey2eJhVtZ44nJyZ7?videoPreview=1 Conjugated polyelectrolytes: Interlayers for perovskite optoelectronic devicesnohttps://cassyni.com/events/xRkJvey2eJhVtZ44nJyZ7?videoPreview=12025-02-06T23:15:00+00:003963.04The MacDiarmid Institute for Advanced Materials and NanotechnologyMetal halide perovskites (MHPs) have attracted significant interest in optoelectronic research due to their exceptional magnetic, electrical, and optical properties. These materials are widely used in various applications such as photovoltaics, light-emitting diodes (LEDs), lasers, photodetectors, field-effect transistors, and solar concentrators. Particularly notable is their application in light-emitting devices, offering high color purity, extensive color tunability, cost-effective manufacturing, and compatibility with solution processing. Perovskite LEDs (PeLEDs) utilizing MHPs exhibit remarkable external quantum efficiencies (EQEs) exceeding 20% in the green, red, and near-infrared spectra. Additionally, perovskite solar cells (PeSCs) have gained attention for their solution processability, customizable band gaps, high absorption coefficients, and long carrier diffusion lengths, resulting in power conversion efficiencies (PCEs) surpassing 26%, comparable to crystalline silicon solar cells. To enhance the performance and stability of PeLEDs and PeSCs, the incorporation of appropriate charge transport layers (CTLs) and/or interlayers is crucial. These layers require suitable energy levels to facilitate efficient charge injection and transport while blocking opposite charges. Moreover, an interlayer based on ionic conjugated molecules can mitigate ion migration by chemically capturing halide and metal ions through electrostatic coulombic interactions. Heat dissipation during device operation is also an important theme to further optimize the perovskite optoelectronic devices. This presentation introduces a series of interfacial layers and CTLs for perovskite optoelectronic devices. https://cassyni-user-files-prod.s3.amazonaws.com/DnV2nq3bso6B9xchJLPsuG https://cassyni.com/events/EoK5dKzVqudPD2nNqEzfsT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/F2qF7Z14jmYpumbBz811ze https://cassyni.com/events/9rq3AVXFTL6Mow52pmHg9K/seminar/qa https://cassyni.com/slides/outline/9rq3AVXFTL6Mow52pmHg9K https://cassyni.com/events/9rq3AVXFTL6Mow52pmHg9K/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PKb4mSTgZdSNkbQV8iPsfU https://cassyni.com/events/9rq3AVXFTL6Mow52pmHg9K?videoPreview=1 Why do native speakers of stress-timed English not consider stress an important linguistic feature?nohttps://cassyni.com/events/9rq3AVXFTL6Mow52pmHg9K?videoPreview=12025-03-28T00:10:00+00:002933.4Linguistics and Applied Language StudiesThere seems to be a paradox in that ELT texts stress the importance of correct stress, and draw attention to lack of comprehension arising from errors in stress production, but native speakers frequently appear to ignore stress. In jokes, rebuses, and even in songs wrong stress is accepted. There is variation within and between dialects in stress patterns. Stress patterns change. Speakers make errors in their production of stress without attracting comment. There seem to be implications for ELT and possibly for phonological theory.https://cassyni-user-files-prod.s3.amazonaws.com/PKb4mSTgZdSNkbQV8iPsfU https://cassyni.com/events/QgJnfdSt2RdSD2UodNhUe1/seminar/qa https://cassyni.com/slides/outline/QgJnfdSt2RdSD2UodNhUe1 https://cassyni.com/events/QgJnfdSt2RdSD2UodNhUe1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Mh5MhLm5Aq4bEH7GbpAf9Y https://cassyni.com/events/QgJnfdSt2RdSD2UodNhUe1?videoPreview=1 Shifting the Paradigm of Aerospace Structural Modeling with AInohttps://cassyni.com/events/QgJnfdSt2RdSD2UodNhUe1?videoPreview=12025-10-14T15:00:00+00:003683.44AIAA JournalAerospace structures increasingly use advanced, anisotropic, and heterogeneous materials whose behavior spans multiple length scales—demanding rigorous multiscale modeling for credible design and analysis. The Mechanics of Structure Genome (MSG) offers a paradigm shift in this arena: it minimizes information loss, overcomes limitations of traditional modeling approaches, and confines all approximations to the constitutive modeling step. In doing so, MSG links microstructural features directly to structural performance while remaining compatible with mainstream aerospace design tools, enabling rapid insertion of new materials early in the design cycle. Yet important barriers persist, including computational cost, scarce or uncertain microstructural data, non-physics-based model assumptions, and limited accessibility for non-experts. Emerging AI/ML methods can overcome these barriers—accelerating multiscale computations, inferring missing microstructural information, enabling natural-language workflow creation, and democratizing access to sophisticated computational tools. Attendees will see how AI-assisted, MSG-based modeling delivers a practical balance of fidelity, speed, and usability—opening a pathway to faster material down-selection, more reliable structural predictions, and broader adoption of advanced modeling tools across the aerospace enterprise.https://cassyni-user-files-prod.s3.amazonaws.com/Mh5MhLm5Aq4bEH7GbpAf9Y https://cassyni.com/events/HGaiyNk1SZKvSzHu5D5rBw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8iBm2X9kRdSbdqciWKoTSW https://cassyni.com/events/KjpkCnyddr6QovmTctzUus/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3mhiZggW33uaEjuNVr6TiN https://cassyni.com/events/Y62rMt9kcHwGhc1GbFZD41/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VhjwVa9Z5ay87akmUV9fq8 https://cassyni.com/events/8NVWRdNGVuTa1SWfvekUUm/seminar/qa https://cassyni.com/slides/outline/8NVWRdNGVuTa1SWfvekUUm https://cassyni.com/events/8NVWRdNGVuTa1SWfvekUUm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/N8nRvB1Ep2TGq7KL6CeBbk https://cassyni.com/events/8NVWRdNGVuTa1SWfvekUUm?videoPreview=1 Development of new carbonic anhydrase inhibitors (CAIs) via virtual screening and multivalent approachesnohttps://cassyni.com/events/8NVWRdNGVuTa1SWfvekUUm?videoPreview=12025-06-20T08:45:00+00:001860.04Anti-Cancer Agents in Medicinal ChemistryThe development of new therapeutic drugs targeting specific disease mechanisms is one of the main goals of medicinal chemistry. In the field of carbonic anhydrase (CA), the lack of selectivity of many active molecules presents a challenge in avoiding toxic effects and improving therapeutic efficacy. In this context, various drug-design approaches can support these goals by integrating computational, chemical, and synthetic tools. For example, the combination of ligand- and pharmacophore-based virtual screening (VS), along with multivalency systems, has emerged as effective strategies to overcome the low selectivity of CA inhibitors (CAIs), offering new opportunities in drug development.https://cassyni-user-files-prod.s3.amazonaws.com/N8nRvB1Ep2TGq7KL6CeBbk https://cassyni.com/events/CpKwqnBzT2SpU6GTqJX3dF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WxWVAR7WLVpsWnLTfGVZ5g https://cassyni.com/slides/outline/7tEcykw9hVsbiDnoToRjim https://cassyni.com/events/7tEcykw9hVsbiDnoToRjim/abstract https://cassyni-user-files-prod.s3.amazonaws.com/B9kxHH1kj6HNpt5dM5TzDL https://cassyni.com/events/7tEcykw9hVsbiDnoToRjim?videoPreview=1 Aerodynamic Optimisation using Direct Numerical Simulationsnohttps://cassyni.com/events/7tEcykw9hVsbiDnoToRjim?videoPreview=12024-12-05T13:00:00+00:002494.76JKW Symposium TeamPyFR is a high-order accurate computational fluid dynamics solver based on the Flux Reconstruction approach. It is written in Python, and can target a range of hardware platforms via an innovative Mako-based domain specific language. Since its inception over 10 years ago, our vision has been to enable scale-resolving simulations for industry. In this talk I will detail our progress to date, and our first steps towards applying PyFR to enable aerodynamic optimisation of rotor blade airfoils for a Martian helicopter using direct numerical simulations.https://cassyni-user-files-prod.s3.amazonaws.com/B9kxHH1kj6HNpt5dM5TzDL https://cassyni.com/events/PgcrySwRWTZ28qntjQhBCh/seminar/qa https://cassyni.com/slides/outline/PgcrySwRWTZ28qntjQhBCh https://cassyni.com/events/PgcrySwRWTZ28qntjQhBCh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XjL4KYX8giFM9jtyrx596n https://cassyni.com/events/PgcrySwRWTZ28qntjQhBCh?videoPreview=1 The power of learning from the bottom up: working towards a blueprint for community-led biodiversity protection and restorationnohttps://cassyni.com/events/PgcrySwRWTZ28qntjQhBCh?videoPreview=12025-08-28T14:30:00+00:001424.72Cambridge PrismsThe impacts of climate change have become more widespread and frequent, and society is beginning to recognise the connection between it and the biodiversity crisis. Communities have the capacity to play a key role in the success of multi-stakeholder nature restoration projects, but examples of successful projects, in which communities are the architects of the action – as opposed to the recipients of it – are not well documented. This study used a participatory evaluation research approach to explore a multi-stakeholder, community-led restoration project at Harper’s Island Wetlands, Co. Cork, Ireland to understand the elements of success and to extract key learnings for other communities. In order to rapidly upscale nature restoration and biodiversity protection globally, there is an urgent need to gain speed and momentum, identifying innovative approaches and disseminating them appropriately. The insights from this case study highlight four key components to be considered by groups at the beginning of community-led projects: setting up a core committee, assigning clear roles within the committee, creating a short-, medium- and long-term strategy and beginning practical tasks as soon as possible. This research serves as a step towards preparing blueprints to inform research, policy and practice in this space to enable stakeholders to respond collectivelyhttps://cassyni-user-files-prod.s3.amazonaws.com/XjL4KYX8giFM9jtyrx596n https://cassyni.com/slides/outline/4RhPeyQUdHzxgXVEp93nBw https://cassyni.com/events/4RhPeyQUdHzxgXVEp93nBw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Xq56YcqgK4tELwAZoEo8BY https://cassyni.com/events/x7u3zzDbg7htLJnxhNnP7/seminar/qa https://cassyni.com/slides/outline/x7u3zzDbg7htLJnxhNnP7 https://cassyni.com/events/x7u3zzDbg7htLJnxhNnP7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VM6E7GFNT6U6q61xt6uE4E https://cassyni.com/events/x7u3zzDbg7htLJnxhNnP7?videoPreview=1 Welcomenohttps://cassyni.com/events/x7u3zzDbg7htLJnxhNnP7?videoPreview=12025-09-18T08:00:00+00:00358.52Imperial College Renal and Transplant CentreWe are delighted to invite you to this year’s Dialysis Academy, hosted by the Imperial College Renal and Transplant Centre, West London. Over two inspiring days, we bring together a truly multidisciplinary audience — locally, nationally, and internationally — united by one goal: to advance the care and quality of life for people receiving dialysis. The Academy is people-centred at its core. Our teaching is led by recognised leaders in the field, with an emphasis on practical, problem-based learning and lively, interactive discussion. We strongly recommend joining us in person at the beautiful, open venue of the Royal Pharmaceutical Society, but we also offer full virtual participation via web conferencing. This year’s programme is rich and stimulating, with sessions including: Home Haemodialysis – Problem-based learning In-Centre Haemodialysis – Problem-based learning Social Determinants of Health in Dialysis Drugs for Anaemia, Diabetes, and Medicine Review Peritoneal Dialysis – Problem-based learning Dialysis in Specific Settings Patient-related Outcome Measures & Quality of Life in Dialysis We are honoured to partner with the Renal Research Institute (New York) and Portsmouth University NHS Hospital, whose strong support enriches this event. We are also proud to welcome our notable visiting speakers: Karin Bergling – Research Scientist, Computational Statistics & Artificial Intelligence, Renal Research Institute, New York Anabell Boyer – Renal Consultant, Centre Hospitalier Universitaire de Caen, France Alirio Martinho Belchior – Lead Nurse, Portsmouth University NHS Hospital Cathy Pogson – Renal Pharmacist, Portsmouth University NHS Hospital Marlene Pluess – Renal Consultant, Hanover Medical School, Germany Whether you are a nurse, therapist, pharmacist, doctor, or specialist trainee in renal medicine, the Dialysis Academy offers practical learning, cutting-edge updates, and a forum for sharing expertise and experience. We look forward to welcoming you to two days of learning, collaboration, and inspiration. Image credit: [Noah (Unsplash)](https://unsplash.com/photos/person-in-white-and-pink-striped-long-sleeve-shirt-ZsyoDh_zek4).https://cassyni-user-files-prod.s3.amazonaws.com/VM6E7GFNT6U6q61xt6uE4E https://cassyni.com/slides/outline/4RPYQ3jjCKoy4yEyi47b1w https://cassyni.com/events/4RPYQ3jjCKoy4yEyi47b1w/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VjCC5rXZ6sDmsiHgCZ9HeW https://cassyni.com/events/4RPYQ3jjCKoy4yEyi47b1w?videoPreview=1 Harnessing the gut microbiome to predict and prevent anticancer drug toxicitynohttps://cassyni.com/events/4RPYQ3jjCKoy4yEyi47b1w?videoPreview=12025-10-15T01:00:00+00:001347.32Microbiome Virtual International ForumAlthough the importance of human genetic polymorphisms and drug-drug interactions in precision medicine is increasingly understood, the role of specific genotypic variants and products elaborated by our “second genome” (the microbiome) has been largely overlooked. In this presentation I will describe a microbiome-informed approach to pharmacology, working to elucidate the direct and indirect mechanisms through which the human microbiome shapes the efficacy and toxicity of small molecule and biologic therapies. I will focus on two recent studies that couple longitudinal sampling of the human gut microbiome during colorectal cancer (CRC) treatment with downstream experiments in cell culture and mouse models. We reveal two distinct mechanisms through which drug-induced shifts in the gut microbiota protect from drug toxicity: drug inactivation and the biosynthesis of chemoprotective metabolites. Furthermore, we demonstrate a proof-of-concept for the use of microbiome profiling and machine learning to predict drug toxicities across independent cohorts. Taken together, these results provide a foundation for future human intervention studies, more in-depth mechanistic dissection in preclinical models, and extension to other cancer treatments.https://cassyni-user-files-prod.s3.amazonaws.com/VjCC5rXZ6sDmsiHgCZ9HeW https://cassyni.com/events/ND4mSDDFq8rwr61F5gnqv5/seminar/qa https://cassyni.com/slides/outline/ND4mSDDFq8rwr61F5gnqv5 https://cassyni.com/events/ND4mSDDFq8rwr61F5gnqv5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UMVumjcfjgBVow8SpDZnG6 https://cassyni.com/events/ND4mSDDFq8rwr61F5gnqv5?videoPreview=1 Systematic Integration of Local Culture in English Lessons to Enhance English Proficiencynohttps://cassyni.com/events/ND4mSDDFq8rwr61F5gnqv5?videoPreview=12025-04-08T00:10:00+00:002978.72Linguistics and Applied Language StudiesThe success of English language instruction is influenced by multiple factors, including the quality and relevance of instructional materials. Recently, scholars have expressed concerns about the global prevalence of English potentially eroding the cultural identities of learners. This study addresses these concerns of the dual challenge by focusing on material development as a systematic approach to integrating local culture into English lessons. Specifically, it examines the creation and implementation of instructional materials rooted in northern Thai culture for young learners in Thailand. Methodologically, the study began with a survey of local northern Thais using a checklist of tourist attractions to identify the eight most culturally representative sites. Based on these attractions, eight English lessons and corresponding multimedia resources were developed and implemented in four elementary schools in northern Thailand over a ten-week period. To evaluate the effectiveness of the lessons, three dimensions were assessed: (1) competence, through pretests and posttests measuring knowledge of northern Thainess and related English vocabulary; (2) performance, via a simulated tour guide task; and (3) attitudes, using a questionnaire to capture psychological responses to the lessons. The findings revealed significant gains in both cultural knowledge and English vocabulary, as evidenced by pretest and posttest comparisons. Students’ successful completion of the simulated tour guide task further demonstrated the practical efficacy of the instructional materials. Additionally, the analysis of questionnaire responses indicated overwhelmingly positive attitudes toward the lessons. These results underscore the potential of systematically designed, culture-based instructional materials to simultaneously enhance language proficiency and foster cultural identity. This study provides critical insights into the intersection of global English education and cultural preservation, emphasizing the value of context-specific material development in elementary education. Keywords: cultural integration, English language education, language proficiency, local culture-based lessons, TBLT, young Thai learnershttps://cassyni-user-files-prod.s3.amazonaws.com/UMVumjcfjgBVow8SpDZnG6 https://cassyni.com/slides/outline/FHeqR5yGrPzSbF51KbMGxm https://cassyni.com/events/FHeqR5yGrPzSbF51KbMGxm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/J5n95f8wLapA6JZTGTWDXU https://cassyni.com/events/FHeqR5yGrPzSbF51KbMGxm?videoPreview=1 Beyond microbes: multiomics reveals the influence of viruses on microbiomesnohttps://cassyni.com/events/FHeqR5yGrPzSbF51KbMGxm?videoPreview=12026-02-10T01:00:00+00:002003.64Microbiome Virtual International ForumMicrobes are driving nutrient and energy transfers across the planet’s ecosystems, but do so under strong constraints exerted by viruses. Over the last decade, metagenomics revolutionized our ability to “see” viruses by providing large genome catalogs for uncultivated viruses, enabling a better characterization of virus-host interactions and their impact on microbiomes. I will present our latest work in this field, including new approaches to maximize the recovery and annotation of viral genomes from metagenomes, analysis of virus-host dynamics across diel cycles and seasons based on paired metagenomes and metatranscriptomes, and unexpected challenges in leveraging CRISPR spacer data to infer virus:host interactions.https://cassyni-user-files-prod.s3.amazonaws.com/J5n95f8wLapA6JZTGTWDXU https://cassyni.com/slides/outline/AphVRkY6nqxYL3eQXSBwGZ https://cassyni.com/events/AphVRkY6nqxYL3eQXSBwGZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XnLiUX946bBT2e4SD5rQnA https://cassyni.com/events/AphVRkY6nqxYL3eQXSBwGZ?videoPreview=1 Microbial Signatures and Functional Shifts in Upper Gastrointestinal Carcinoma: A Metagenomic Analysisnohttps://cassyni.com/events/AphVRkY6nqxYL3eQXSBwGZ?videoPreview=12026-06-02T00:30:00+00:00457.2Microbiome Virtual International Forum"Introduction: Upper gastrointestinal (UGI) carcinoma is one of the significant causes of global cancer mortality, in which the human microbiome plays a crucial role in the immune system and inflammation. Previously, the focus of taxonomic variation was on analyzing taxonomic variation, and differential taxa were reported to be linked with the UGI cancer, but the functional structure of microbial communities, especially in biopsy and mucosal swab samples, is not well-characterized. The study will examine microbial richness, evenness, differential biomarkers, and changes in functional pathways associated with UGI carcinoma using high-resolution 16S rRNA metagenomic profiling data. Methodology: Publicly available 16S rRNA sequencing data were collected from the ENA Browser and processed using the DADA2 denoising pipeline within QIIME2, including quality filtering, chimera removal, and rarefaction. A total of 2,461 high-quality amplicon sequence variants (ASVs) and 282 samples passed rarefaction thresholds. Alpha diversity was assessed using standard indices, and beta diversity was evaluated using Bray-Curtis and UniFrac distances, compared by PERMANOVA, and visualized using NMDS. Differential abundance analysis was performed using a Zero-Inflated Generalized Mixed Model (ZIGMM) at an adjusted p-value threshold of < 0.05 with a minimum relative abundance of 0.01%. MetaCyc pathway inference enabled functional predictions, and linear discriminant analysis (LDA) was used to identify differentially enriched pathways across sample types. Results: The microbial richness of carcinoma tissues was higher, and there was a greater compositional divergence compared to the adjacent normal tissues. The evenness increased, but beta-diversity separation was not strong in carcinoma swabs. ZIGMM analysis identified 32 differentially abundant taxa in mucosal swab samples (12 enriched in carcinoma, 20 in normal) and 51 in tissue biopsy samples (12 enriched in carcinoma, 39 in normal). Helicobacter pylori and Acinetobacter sp. were consistently enriched in carcinoma samples across both sample types, while Kaistella haifensis, Epilithonimonas hominis, Prevotella copri, Parvimonas micra, and Stenotrophomonas sp. were specifically enriched in carcinoma biopsies. Normal tissues were marked by the relative abundance of Streptococcus, Rothia mucilaginosa, Novosphingobium capsulatum, and Nitrospirillum sp. Across 43 predicted MetaCyc pathways, 24 were identified in tissue biopsy samples (10 enriched in carcinoma, 14 in adjacent normal tissue) and 19 in mucosal swab samples (11 enriched in carcinoma, 8 in normal). In tissue biopsies, heme b biosynthesis II and L-tryptophan biosynthesis were the most strongly enriched pathways in normal tissue (LDA > 3.2), while carcinoma biopsies showed enrichment for the incomplete reductive TCA cycle I and dTDP-β-L-rhamnose biosynthesis. In mucosal swabs, aerobic respiration I and L-tryptophan biosynthesis were enriched in normal samples, whereas carcinoma swabs were characterized by enrichment of glycogen degradation I, fatty acid biosynthesis initiation, and O-antigen biosynthesis pathways Conclusion: This study offers detailed data on taxonomic and functional microbial signatures linked to UGI carcinoma. The functional pathways unique to tissues and swabs observed indicate microbial changes associated with malignancy. Future research will go further to discover the important bacterial genes that are behind these pathways and perform molecular docking studies to understand possible drug interactions to regulate bacteria-specific genes."https://cassyni-user-files-prod.s3.amazonaws.com/XnLiUX946bBT2e4SD5rQnA https://cassyni.com/events/XZxVV6E2dS94rckhtwjmD7/seminar/qa https://cassyni.com/slides/outline/XZxVV6E2dS94rckhtwjmD7 https://cassyni.com/events/XZxVV6E2dS94rckhtwjmD7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3LZ9ChngyPWmTbZCRwFFFk https://cassyni.com/events/XZxVV6E2dS94rckhtwjmD7?videoPreview=1 Money, Time, and Information: Inspirations from Gödel, Tarski, and Chaitinnohttps://cassyni.com/events/XZxVV6E2dS94rckhtwjmD7?videoPreview=12025-09-24T14:00:00+00:005652.04Logica UniversalisModeling money as a formal language that quantifies prices and allocations of goods and services reveals surprisingly novel insights into the intricate web that connects money, time, and information. These insights have crucial implications for economic theory and policy.https://cassyni-user-files-prod.s3.amazonaws.com/3LZ9ChngyPWmTbZCRwFFFk https://cassyni.com/slides/outline/SeuCrN2ynFrCJjm2zLZR4Z https://cassyni.com/events/SeuCrN2ynFrCJjm2zLZR4Z/abstract https://cassyni-user-files-prod.s3.amazonaws.com/USJFKHkbUr1g2DnVAARqeE https://cassyni.com/events/SeuCrN2ynFrCJjm2zLZR4Z?videoPreview=1 An intrinsic neuronal manifold underlies brain-wide hierarchical organization of behavior in C. elegansnohttps://cassyni.com/events/SeuCrN2ynFrCJjm2zLZR4Z?videoPreview=12025-05-09T19:00:00+00:003749.12AI Institute in Dynamic SystemsLarge-scale neuronal recordings have revealed complex behavior-related activity patterns. Surprisingly, these patterns are broadly distributed across brain regions, including sensory areas. The origins and functions of such activity patterns are incompletely understood. Using whole-brain imaging in freely behaving C. elegans, we find rich and distributed brain activity. Within these dynamics, a low dimensional manifold encodes the major action sequence of C. elegans. This manifold originates largely from intrinsic dynamics, with minor contributions from movement-induced sensations. Moreover, multiple neurons encode faster time-scale motor patterns that are gated by the manifold, meaning that they selectively encode behavior during specific brain states. We therefore propose that one function of brain-wide dynamics is to enable hierarchical organization of behavior: information about major actions is broadcast via a distributed manifold, which enables the hierarchical nesting of granular motor patterns within those major actions.https://cassyni-user-files-prod.s3.amazonaws.com/USJFKHkbUr1g2DnVAARqeE https://cassyni.com/events/DKPtbuZovttmfKqDg6Vob3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CNtosEW7pwJCy7nGrSoG9L https://cassyni.com/slides/outline/Jj8QPwvGctfvnsSdXpiQiZ https://cassyni.com/events/Jj8QPwvGctfvnsSdXpiQiZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TMGes6NqXQLVZSgpcDFnQ6 https://cassyni.com/events/Jj8QPwvGctfvnsSdXpiQiZ?videoPreview=1 Effects of m6A loss on immunity and polyadenylation in Arabidopsis thaliananohttps://cassyni.com/events/Jj8QPwvGctfvnsSdXpiQiZ?videoPreview=12025-08-07T09:15:00+00:00929.16NoneRNA modifications are critical for distinguishing self from non-self in humans, with implications for immunity and development. In humans, mRNA modifications, such as N6-methyladenosine (m6A), are essential for modulating immune responses and central to mRNA therapeutic advancements. Similarly, in *Arabidopsis*, m6A modifications mediated by the mRNA writer complex (including VIRILIZER) are vital for viability, with loss-of-function mutations causing severe and often lethal developmental defects. We investigated the role of m6A in *Arabidopsis* and discovered that disrupting the writer complex produces a temperature-sensitive autoimmune phenotype. Mutants exhibit increased basal resistance to pathogens, heightened cell death, and immune gene dysregulation, suppressed at elevated temperatures. In contrast, the developmental defects in these mutants are not temperature-sensitive, indicating separable impacts of m6A loss on autoimmunity and development. Alongside the autoimmune response, we observe temperature-sensitive changes to poly(A) tail length distributions in writer mutants. These changes were not restricted to genes with predicted m6A modification, suggesting global disruption in poly(A) processing which could be a result of, or lead to, the autoimmune response. These findings highlight m6A as a critical regulator of immune homeostasis in plants, and indicate a possible connection between m6A modification, poly(A) tail length and autoimmune response.https://cassyni-user-files-prod.s3.amazonaws.com/TMGes6NqXQLVZSgpcDFnQ6 https://cassyni.com/slides/outline/RAY3zsN7RUHxR65cJGS9T3 https://cassyni.com/events/RAY3zsN7RUHxR65cJGS9T3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FMYmNoQ9KJHRPJ9WLU1m3k https://cassyni.com/events/RAY3zsN7RUHxR65cJGS9T3?videoPreview=1 What should I know about Digital Sequence Information (DSI) and sharing benefits under the CBD?nohttps://cassyni.com/events/RAY3zsN7RUHxR65cJGS9T3?videoPreview=12025-05-05T10:00:00+00:001216.6Microbiome Virtual International ForumAt the UN Biodiversity Conference (COP16) in Cali, Colombia in October 2024 new decisions were reached on how benefits can and should be shared from digital sequence information (DSI). The COP16 DSI Decision 16/2 operationalizes a new benefit-sharing mechanism under the Convention on Biological Diversity (CBD) and creates new financial obligations for commercial users of DSI through a sector-based multilateral mechanism called the Cali Fund. The decision also ensures that non-commercial users of DSI can continue to publish in and use sequences in open access databases although DSI databases have new requirements imposed on them. This benefit-sharing approach differs from the bilateral approached under the CBD's Nagoya Protocol. The talk will explain what the DSI decision means for “real-world” scientists, database managers, and users of sequence data. And, in parallel, show what science policy work entails and what is happening on the ground during UN negotiations. https://cassyni-user-files-prod.s3.amazonaws.com/FMYmNoQ9KJHRPJ9WLU1m3k https://cassyni.com/slides/outline/AM5vcMxNFjgL79nuHccQuK https://cassyni.com/events/AM5vcMxNFjgL79nuHccQuK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JYwd5qnD9urN4HfhHvB9MQ https://cassyni.com/events/AM5vcMxNFjgL79nuHccQuK?videoPreview=1 Changes and continuities in national research evaluation systems in the context of the global reform of research assessmentnohttps://cassyni.com/events/AM5vcMxNFjgL79nuHccQuK?videoPreview=12025-06-23T12:00:00+00:005324.84Several processes of reform of research evaluation systems are underway around the world. What until a few years ago were declarations and proposals for change are now being implemented. In countries with relatively less developed scientific and technological systems, transformations have also been carried out, although little is known about the particular challenges that these countries must face. This virtual symposium brings together researchers from Portugal, Argentina and Uruguay to reflect on the process of chance in national research evaluation systems in the context of the global reform of research assessment. We propose a discussion that seek to debate how could the current transformation process be an opportunity to design a research governance system that seeks to improve the quality of science while preserving the possibility of solving problems relevant to each country. The moderated panel discussion includes short presentations focus on aspects related to responsible research assessment in each country. This is followed by a discussion on challenges and lessons learned which can help inform and inspire future implementation efforts.https://cassyni-user-files-prod.s3.amazonaws.com/JYwd5qnD9urN4HfhHvB9MQ https://cassyni.com/events/KDn1SdZo4MDyndyX8G1Cys/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PSNhaDGnx3yjpzPntUWQgv https://cassyni.com/events/7rs7NugixpUzWPzNmGZRxy/seminar/qa https://cassyni.com/slides/outline/7rs7NugixpUzWPzNmGZRxy https://cassyni.com/events/7rs7NugixpUzWPzNmGZRxy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DVruTJhPVa2kvRQYqft8ES https://cassyni.com/events/7rs7NugixpUzWPzNmGZRxy?videoPreview=1 Capillary aggregation and surface waves in bacterial coloniesnohttps://cassyni.com/events/7rs7NugixpUzWPzNmGZRxy?videoPreview=12025-11-20T15:00:00+00:004149.4Journal of Biological PhysicsMany bacteria inhabit hydrated environments like soil, textiles and agar hydrogels in the lab. In these environments, cells are surrounded by a water meniscus. First, I will show that the resulting capillary forces organize bacterial colonies, enabling cells to aggregate into densely packed nematic layers while still allowing them to slide past one another. Second, I will show that, when these bacterial colonies form thick multilayered films, they exhibit active surface waves. These results suggest that capillary forces may be a ubiquitous physical ingredient in shaping microbial communities in partially hydrated environments.https://cassyni-user-files-prod.s3.amazonaws.com/DVruTJhPVa2kvRQYqft8ES https://cassyni.com/events/HFDDNXVahswKFAVUNgDYS9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8APu2rh1ttV4Y1aYMQ3CMC https://cassyni.com/events/KiTEbwjCuAhoc6y2vN8BA5/seminar/qa https://cassyni.com/slides/outline/KiTEbwjCuAhoc6y2vN8BA5 https://cassyni.com/events/KiTEbwjCuAhoc6y2vN8BA5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CmtW6xvjLZKdRokJZp78TY https://cassyni.com/events/KiTEbwjCuAhoc6y2vN8BA5?videoPreview=1 Combination of HDAC Inhibition and Cytokine Enhances Therapeutic HPV Vaccine Therapynohttps://cassyni.com/events/KiTEbwjCuAhoc6y2vN8BA5?videoPreview=12026-07-16T16:30:00+00:003131.32Center for Cancer TrainingBackground: HPV-associated malignancies continue to present a major health concern despite the development of prophylactic vaccines. Standard therapies offer limited benefit to patients with advanced stage disease. Despite improved outcomes with PD-1 targeted therapies, treatment resistance and modest response rates highlight a significant unmet need to develop novel therapies for these patients. PDS0101 (designated HPV vaccine) is a liposomal nanoparticle HPV16-specific therapeutic vaccine that has been shown to generate strong HPV-specific responses in pre-clinical and clinical studies. Here we assess the efficacy of this HPV vaccine in combination with the tumor-targeting immunocytokine NHS-IL12 (PDS01ADC), plus either aPD-1 or the class I histone deacetylase (HDAC) inhibitor Entinostat. Methods: Mice bearing HPV16+, aPD-1 refractory TC-1 and mEER tumors were treated with HPV vaccine, NHS-IL12, and either aPD-1 or Entinostat to determine anti-tumor efficacy and survival benefits. A comprehensive analysis of the tumor microenvironment was performed using flow cytometry, multiplex immunofluorescence, chemokine and cytokine assessment, and scRNAseq with TCR enrichment. Results: Combination of HPV vaccine and NHS-IL12 with either Entinostat or aPD-1 yields significant anti-tumor activity and prolonged survival in aPD-1 refractory models of HPV16+ cancer, with superior activity employing Entinostat versus aPD-1 combination. Entinostat triple therapy increased overall and HPV16-specific tumor CD8+ T cell infiltration with heightened cytotoxicity. TCR sequencing revealed a CD8+ T cell clone unique to vaccine-treated cohorts, which displayed an enriched cytotoxic transcriptional profile with triple therapy. These effects were parallelled by strong differentiation of tumor-associated macrophages (TAMs) towards proinflammatory, anti-tumor M1-like cell states. Single-cell transcriptomic analysis indicated all three agents were required for highest modulation of both CD8+ T cells and TAMs conducive to tumor control. A biomarker signature reflecting the pre-clinical findings was found to be associated with improved survival in patients with HPV-associated malignancies. Conclusion: Together, these findings provide a rationale for the combination of HPV vaccine, NHS-IL12, and Entinostat in the clinical setting for patients with HPV16-associated malignancies. https://cassyni-user-files-prod.s3.amazonaws.com/CmtW6xvjLZKdRokJZp78TY https://cassyni.com/events/GFXHgLz8Burd7fEDz6rsKB/seminar/qa https://cassyni.com/slides/outline/GFXHgLz8Burd7fEDz6rsKB https://cassyni.com/events/GFXHgLz8Burd7fEDz6rsKB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Ew7Di81CVGF2JuHDWJEVoC https://cassyni.com/events/GFXHgLz8Burd7fEDz6rsKB?videoPreview=1 Nonlinear damping in large-amplitude vibrations of structures: modelling and experimentsnohttps://cassyni.com/events/GFXHgLz8Burd7fEDz6rsKB?videoPreview=12026-02-10T14:00:00+00:002640.64Nonlinear Dynamics, an International Journal of Nonlinear Dynamics and Chaos in Engineering SystemsAn increase in damping is relevant for the passive control of vibrations and noise; therefore, it is very relevant in design. Experimental data show a strong and nonlinear dependence of damping on the vibration amplitude for beams, plates, and shells of different sizes and made of different materials (metal, composite materials, silicone rubber, and graphene). While the frequency shift of resonances due to stiffness nonlinearity is 10 to 25 % at most for common structural elements, a damping value up to several times larger than the linear one can be obtained for vibrations of thin plates when the vibration amplitude is about twice the thickness. This is a huge change in the damping value! Therefore, the nonlinear nature of damping affects structural vibrations much more than stiffness nonlinearity. Despite this experimental evidence, nonlinear damping has not been sufficiently studied yet. A model of nonlinear damping was derived from linear viscoelasticity for single-degree-of-freedom systems and rectangular plates by taking into account geometric nonlinearity. The resulting damping model was nonlinear, and the model parameters were identified from experiments. Numerical results for forced vibration responses of different structural elements in large-amplitude (nonlinear) regimes were obtained and successfully compared to experimental results, validating the nonlinear damping model. **Key Learning Objectives** - How good is it to model damping as linear viscous damping? - Is damping slightly or significantly nonlinear during large-amplitude (nonlinear) vibrations of structural elements? - Nonlinear damping is very important in the design of major systems under extreme conditions, like the core of a nuclear reactor subjected to earthquakes - Ignoring nonlinear damping has the consequence of over-design of structures and systems for extreme events that may never happen during the structure’s life. **Who Should Attend** - Mechanical engineers - Aerospace engineers - Civil Engineers - Researchers/scientists in mechanical sciences and dynamics - Research/Project managers - Heads of research divisions in mechanical design and dynamicshttps://cassyni-user-files-prod.s3.amazonaws.com/Ew7Di81CVGF2JuHDWJEVoC https://cassyni.com/slides/outline/TSftgpokrdt4sKHAbFpCu https://cassyni.com/events/TSftgpokrdt4sKHAbFpCu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PSD3fdYvw3sDXdtspRUMjt https://cassyni.com/slides/outline/GGtoHCEYvbFEKV2egdjB4y https://cassyni.com/events/GGtoHCEYvbFEKV2egdjB4y/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VNG3nvQmmbbGe3HLAfHTpJ https://cassyni.com/events/GGtoHCEYvbFEKV2egdjB4y?videoPreview=1 Aotearoa: A Tech-Driven Sustainable Nation?nohttps://cassyni.com/events/GGtoHCEYvbFEKV2egdjB4y?videoPreview=12022-11-04T00:00:00+00:006832.36Business SchoolNew Zealand faces significant sustainability challenges, with national emissions increasing by 60% since 1990 and a notable gap between organisational carbon neutrality aspirations and concrete actions. Globally, pervasive issues such as radical inequality, resource depletion, and climate change underscore the urgent need for integrated solutions. Technological approaches, including digital transformation, advanced analytics, AI, digital twin simulations, and IoT, are explored across sectors like transport, energy, and agriculture. Systemic frameworks like Fairtrade certification for transparent supply chains and policy advocacy for a national technology roadmap are also examined. Studies indicate that leveraging existing digital technologies could address 42% of New Zealand's 2030 carbon emissions target. Migration to hyper-scale cloud infrastructure is shown to reduce IT carbon emissions by up to 98%. Practical applications, such as a digital twin implementation for a Coca-Cola bottler, demonstrated a 9% reduction in energy consumption over a 12-week trial. However, significant disparities persist, with 26 individuals controlling over 50% of global wealth, and modern slavery, a $160 billion annual profit industry, further illustrates deeply entrenched systemic issues. Findings underscore technology's potential for significant sustainability improvements, from operational efficiencies to supply chain accountability. Achieving genuine sustainability requires systemic paradigm shifts beyond technological fixes, encompassing greater transparency, equitable wealth distribution, and policy alignment with environmental and social objectives. Integrating sustainability into core business decisions and addressing digital equity are essential for fostering a resilient, fair, and sustainable future, with New Zealand demonstrating potential global leadership.https://cassyni-user-files-prod.s3.amazonaws.com/VNG3nvQmmbbGe3HLAfHTpJ https://cassyni.com/slides/outline/Aqm9mg7n6ZA9vcnR5ijP5X https://cassyni.com/events/Aqm9mg7n6ZA9vcnR5ijP5X/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7wwpAhPdfLGhTK81krRPUz https://cassyni.com/events/Aqm9mg7n6ZA9vcnR5ijP5X?videoPreview=1 Digital Sustainability Panel: Space-Based Earth Observation Data Enabling Sustainable Decision-Makingnohttps://cassyni.com/events/Aqm9mg7n6ZA9vcnR5ijP5X?videoPreview=12022-02-09T00:00:00+00:003847.48Business SchoolSpace-based Earth Observation (EO) data offers transformative potential for sustainable decision-making by providing critical tools for planetary stewardship and enhancing environmental consciousness. Addressing the vast scale of global challenges—from monitoring extensive land and maritime domains to climate change and biodiversity loss—modern EO integrates diverse remote sensing technologies (e.g., multi-spectral, hyperspectral, Synthetic Aperture Radar, GNSS, IoT) with advanced AI and deep learning. Applications include precise forestry management (tree health, density, carbon accounting), optimizing agricultural practices (e.g., virtual fencing, fertilizer use), and maritime domain awareness (combating illegal fishing, oil spills, biosecurity). Notable initiatives, such as the MethaneSAT mission, specifically target a 45% reduction in oil and gas methane emissions by 2025, with parallel efforts on agricultural sources, demonstrating significant environmental impact potential. However, the effective deployment of EO for sustainability faces challenges. Beyond the conceptual ambiguity of "sustainability," its impact is shaped by external factors like regulations, values, and norms. Pragmatic obstacles include high data access costs, complexities from heterogeneous data, and underestimation of development time and cost. Firms also struggle to align products with customer needs, often lacking specialized domain expertise or clear arguments for cost-effectiveness, and facing customer uncertainty, sometimes diverted by lucrative government contracts from broader sustainability applications. Overcoming these barriers is essential for EO to fully realize its promise in global sustainability efforts.https://cassyni-user-files-prod.s3.amazonaws.com/7wwpAhPdfLGhTK81krRPUz https://cassyni.com/events/7Mt2xfrZh2pB5Nkbs5WGcm/seminar/qa https://cassyni.com/slides/outline/7Mt2xfrZh2pB5Nkbs5WGcm https://cassyni.com/events/7Mt2xfrZh2pB5Nkbs5WGcm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TnkNUqyTpk4iSZcn9ZSeDC https://cassyni.com/events/7Mt2xfrZh2pB5Nkbs5WGcm?videoPreview=1 Flow and rheology of elongated grainsnohttps://cassyni.com/events/7Mt2xfrZh2pB5Nkbs5WGcm?videoPreview=12026-05-11T13:00:00+00:004555.4Granular MatterGranular flows of elongated particles present interesting properties, in particular secondary vortices that can e.g. generate heaping. In this talk, I will consider the idealised configuration of a simple shear cell to study when and how an additional longitudinal forcing can induce transverse secondary flows [1]. I will relate this effect to normal stress differences, which are enhanced for more elongated and frictional grains [2]. https://cassyni-user-files-prod.s3.amazonaws.com/TnkNUqyTpk4iSZcn9ZSeDC https://cassyni.com/events/EGxVcEuuqSZxaBkBEX5CmT/seminar/qa https://cassyni.com/slides/outline/EGxVcEuuqSZxaBkBEX5CmT https://cassyni.com/events/EGxVcEuuqSZxaBkBEX5CmT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/YCepub5d3YeBj4KCVkaeZL https://cassyni.com/events/EGxVcEuuqSZxaBkBEX5CmT?videoPreview=1 Intersections of Faith, Feminism, and Activism: Progressive Islam and Social Justicenohttps://cassyni.com/events/EGxVcEuuqSZxaBkBEX5CmT?videoPreview=12026-04-16T16:00:00+00:003207.04Lived Places PublishingSexism and patriarchy remain dominant infrastructures in today's world. Reshaping that infrastructure and the centuries-old mindset that accompanies it requires collective engagement and action from us all, working in allyship with one another. It is only when we lift each other up collectively that we can finally dismantle the walls of inequality and oppression built by the patriarchy. **Ani Zonneveld** exemplifies this spirit as a pioneering voice for progressive Islam and social justice. She is an award winning songwriter, Founder and President of Muslims for Progressive Values, and author of the book, [An Unlikely Social Justice Warrior: Making My Life Count as a Muslim Feminist](https://livedplacespublishing.com/book/isbn/9781917566995). In this session, Ani shares her personal and professional experiences in advocating for human rights, gender equality, and religious freedom. Participants will gain a deeper understanding of the intersections between faith, feminism, and activism and the various initiatives she's created in countering patriarchy and sexism in society including her advocacy for LGBTQ+ rights and in opposing the misuse of religion to justify prejudice.https://cassyni-user-files-prod.s3.amazonaws.com/YCepub5d3YeBj4KCVkaeZL https://cassyni.com/events/Mi44uLsD9zGMbNJqypuWey/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4H46bkzisAyre7biD2ZuC2 https://cassyni.com/slides/outline/JFWqaZLY5nPiZg1HLAXZ89 https://cassyni.com/events/JFWqaZLY5nPiZg1HLAXZ89/abstract https://cassyni-user-files-prod.s3.amazonaws.com/En5YA3JRySFaGGB27N9fHQ https://cassyni.com/events/JFWqaZLY5nPiZg1HLAXZ89?videoPreview=1 Some eigenvalue problems involving “Epsilon-near-zero” materials with dielectric inclusionsnohttps://cassyni.com/events/JFWqaZLY5nPiZg1HLAXZ89?videoPreview=12025-06-16T07:00:00+00:001358.24ETOPIMThis talk will present some results on eigenvalue problems in photonics arising from the use of “Epsilon-near-zero” (ENZ) materials. We begin with two and three dimensional problems of a closed resonator with PEC boundary conditions: the resonator is made up of an ENZ background with one or more dielectric inclusions in the interior– in applications these are exciting because in certain settings they are, at leading order, insensitive to the geometry of the outer shell and only depend on the geometry of the inclusions (and in 2D, the area of the shell). In two dimensions we are led to a complete understanding of the robustness of such a resonator for nonzero, but small |δ|. In three dimensions while answering the same robustness question we are led to an interesting and non-standard generalized eigenvalue problem that we completely analyze for both simple, and multiple eigenvalues. When the inclusion is spherical, we demonstrate that infinitely many “electrostatic” resonances exist where the magnetic field vanishes to leading order in the shell. This part of the talk is joint work with Robert V. Kohn (NYU). Time permitting, we will then consider a class of disordered two-phase composites with dielectric inclusions in an ENZ background, and show that the resulting divergence form operator, -∇. ε ^-1 ∇ describing TM waves, possess band gaps (not unlike periodic composites), provided the inclusion centers satisfy a typeruniformity condition. This analysis validates studies based on numerical experiments by Torquato and collaborators. This work is based on joint work with Kerrek Stinson (U. Utah). https://cassyni-user-files-prod.s3.amazonaws.com/En5YA3JRySFaGGB27N9fHQ https://cassyni.com/slides/outline/LikroyaAH5ACvcUqsrSBr5 https://cassyni.com/events/LikroyaAH5ACvcUqsrSBr5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Xh1UiTHSbMJ9FhZjX44H7U https://cassyni.com/events/LikroyaAH5ACvcUqsrSBr5?videoPreview=1 Global and local gaps in periodic medianohttps://cassyni.com/events/LikroyaAH5ACvcUqsrSBr5?videoPreview=12025-06-17T05:00:00+00:001455.0ETOPIMWe consider acoustic wave propagation through a periodic array of small inclusions of arbitrary shape. The inclusion size a is much smaller than the array period, while the wavelength is fixed. This problem is a singular perturbation of the problem without inclusions, and its solution does not converge to an unperturbed wave when a → 0. However, the dispersion surface is close to the one for the inclusionless problem, and this implies the absence of global gaps in any fixed interval (ε, ε−1 ) of the time frequency ω if a is small enough. The notion of local gaps, which depends on the choice of a wave vector k, will be introduced and studied.https://cassyni-user-files-prod.s3.amazonaws.com/Xh1UiTHSbMJ9FhZjX44H7U https://cassyni.com/slides/outline/V7n8bba5jraC5wqJwhmF4y https://cassyni.com/events/V7n8bba5jraC5wqJwhmF4y/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4QBqugnhLoiNTMv14HeMH8 https://cassyni.com/events/V7n8bba5jraC5wqJwhmF4y?videoPreview=1 Bounds and limitations on quasi-static passive cloakingnohttps://cassyni.com/events/V7n8bba5jraC5wqJwhmF4y?videoPreview=12025-06-18T03:00:00+00:001870.0ETOPIMIn this talk, we discuss our recent results [1] on the following challenging question: is it possible to use a passive cloak to make invisible a dielectric inclusion on a finite frequency interval in the quasistatic regime of Maxwell’s equations for an observer close to the object? First, we will present our theorem that gives the answer to this question: No one cannot due to the passivity of the cloaking device. Second, we discuss how the passivity assumption allows us to derive sum rules for the Dirichlet-to-Neumann map in the near-field cloaking problem, based on its properties related to two important classes of analytic functions, namely, Herglotz and Stieltjes functions. Third, we present our theorem on bounds that impose fundamental limits on passive cloaking devices over a finite frequency interval. These results extend, to the near-field problem, those of [2] for the farfield problem by combining two techniques for producing bounds: i) variational bounds (using the Dirichlet and Thomson variational principles) from abstract theory of composite framework [3, 4, 5]; ii) the analytic approach to bounds using sum rules for passive systems [2, 6]. https://cassyni-user-files-prod.s3.amazonaws.com/4QBqugnhLoiNTMv14HeMH8 https://cassyni.com/slides/outline/Xb29q1ohw9LgStJsVPfsnu https://cassyni.com/events/Xb29q1ohw9LgStJsVPfsnu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Np82iTM1KjmZGKN5E6pZpr https://cassyni.com/events/Xb29q1ohw9LgStJsVPfsnu?videoPreview=1 Tight limits to the Hall effect and other nonreciprocal effects in 3D compositesnohttps://cassyni.com/events/Xb29q1ohw9LgStJsVPfsnu?videoPreview=12025-06-19T23:00:00+00:001401.16ETOPIMWhile it is well known that composite materials can exhibit unusual effective properties going beyond those of their constituents, the extent to which this applies to nonreciprocal composites is presently not well understood. In this talk, I will report on our recent progress on this problem: First, I will present new bounds on the effective material properties of composites that are made from at least one constituent material exhibiting a nonreciprocal effect. It is assumed that the underlying equations are those of the conductivity problem and that the antisymmetric contribution to the tensor describing the constituent material properties is small. Emphasis will be given to the Hall effect. However, as many other nonreciprocal effects take the same form in the mathematical description, our results are more generally applicable. Second, I will discuss the attainability of our new bounds. In particular, I will show that in the important high-contrast regime many of our new bounds are attained by hierarchical laminate microstructures. While these laminates show optimal behavior, their structure involves several separated length scales, which renders their practical realization difficult or even infeasible. Using topology optimization, we obtained much more realistic microstructures. These topology optimized microstructures show a performance that generally approximates their multi-scale counterparts well.https://cassyni-user-files-prod.s3.amazonaws.com/Np82iTM1KjmZGKN5E6pZpr https://cassyni.com/slides/outline/FGHKpEir7ibqPRGad4UyCy https://cassyni.com/events/FGHKpEir7ibqPRGad4UyCy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RjCw6ModAGmQdvAJAgPhSN https://cassyni.com/events/FGHKpEir7ibqPRGad4UyCy?videoPreview=1 Terminator periodic orbits around binary asteroids: an application to the ESA Hera mission, Second-order modeling of the Cassini states of large satellitesnohttps://cassyni.com/events/FGHKpEir7ibqPRGad4UyCy?videoPreview=12026-03-30T13:00:00+00:003913.24Celestial Mechanics and Dynamical AstronomyResearch in celestial mechanics addresses challenges in spacecraft mission design and the dynamics of planetary bodies. One study investigated terminator periodic orbits (TPOs) for the ESA Hera mission in the Didymos–Dimorphos binary asteroid system. Using analytic continuation, eight distinct TPO families were identified in a non-rotating frame, classified into unstable (Group I, with resonant angle ϕ_R = 0) or quasi-stable/stable (Group II, with ϕ_R = π) configurations. In a rotation model, the Coriolis force caused slow orbital drift, but characteristic terminator properties (inclination ≈90°, ascending node ≈±90°) were preserved for approximately 200 days. Optimized initial conditions limited orbital deviations to below 25 m for 30 days and 40 m for two months, demonstrating suitability for Hera's parking. A separate study developed a second-order dynamical model for Cassini states in large satellites, specifically Cassini state 1 for the Galilean moons. This model incorporated the full gravitational torque and coupled obliquity with polar motion, quantifying nutations in obliquity and longitude. Inertial obliquity exhibited primarily semidiurnal nutation, while body-frame obliquity showed predominantly diurnal nutation. For Callisto, diurnal nutations reached 400 milliarcseconds (40 m on surface), and second-order polar motion was resonantly amplified by factors up to 60. The presence of a subsurface ocean was shown to significantly influence Cassini state 1, causing resonant amplification of obliquity and polar motion for certain ocean thicknesses (e.g., 100-500 km for Ganymede), offering constraints for internal structures.https://cassyni-user-files-prod.s3.amazonaws.com/RjCw6ModAGmQdvAJAgPhSN https://cassyni.com/slides/outline/6tbwWqTTzFejHS28yB5n7F https://cassyni.com/events/6tbwWqTTzFejHS28yB5n7F/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Dsea548iqiPi4yf22N5sHg https://cassyni.com/events/6tbwWqTTzFejHS28yB5n7F?videoPreview=1 Decadal trends in phytoplankton community composition and seasonalitynohttps://cassyni.com/events/6tbwWqTTzFejHS28yB5n7F?videoPreview=12025-07-08T12:00:00+00:002084.12NonePhytoplankton, the base of aquatic food-webs, has a pronounced seasonality in temperate waters. Not just the total biomass, but also the species composition during the phytoplankton spring bloom is very different from the following summer season.  We analyse trends in alpha and beta diversity, and seasonality using a half century (1967–2018) phytoplankton time series from a confined coastal are in the Helsinki Archipelago, the northern Baltic Sea. We hypothesise that seasonality is a complementary and sensitive metrics to detect environmental changes in coastal habitats.  The community ordination revealed a robust temporal ordering of samples, emphasizing the influence of time on phytoplankton composition (GAM fit: R² = 0.9). Species richness showed a consistent increase over time and emerged as the most influential descriptor related to community structure (GAM fit: R² = 0.56–0.70). Changes in species richness accounted for approximately 35–36% of the mean between-sample beta diversity, leaving the remaining 64–65% attributed to species turnover—the dominant component of the biodiversity trend. Temporal decay of community similarity revealed rapid turnover rates, with a halving time of 24 years in the outer archipelago and 11 years in the inner bays, reflecting differences in eutrophication strength. https://cassyni-user-files-prod.s3.amazonaws.com/Dsea548iqiPi4yf22N5sHg https://cassyni.com/events/DHiXk8edmFKAqwnXsUhJfF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/712nVkj5s3jVXtAk8zdPti https://cassyni.com/events/FkxYyYtFxY5fCtG6RAbwPB/seminar/qa https://cassyni.com/slides/outline/FkxYyYtFxY5fCtG6RAbwPB https://cassyni.com/events/FkxYyYtFxY5fCtG6RAbwPB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AKZexHAuKCsUK1rfSo6TWW https://cassyni.com/events/FkxYyYtFxY5fCtG6RAbwPB?videoPreview=1 Frontiers in RNA Therapeutics and Translational Medicinenohttps://cassyni.com/events/FkxYyYtFxY5fCtG6RAbwPB?videoPreview=12026-06-01T08:00:00+00:005881.72Thieme BioSciencesThe webinar Frontiers in RNA Therapeutics and Translational Medicine will bring together leading experts to discuss recent advances in RNA-based therapeutics and their applications in translational medicine. The session will feature Prof. Hiroshi Abe (Nagoya University) and Prof. Rakesh N. Veedu (Murdoch University), and will be chaired by Dr. Vitor Bernardes Pinheiro (KU Leuven).https://cassyni-user-files-prod.s3.amazonaws.com/AKZexHAuKCsUK1rfSo6TWW https://cassyni.com/events/Ng4djkTVWJmArUXv31iePf/seminar/qa https://cassyni.com/slides/outline/Ng4djkTVWJmArUXv31iePf https://cassyni.com/events/Ng4djkTVWJmArUXv31iePf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/S6h8ssYGVNBUtf8dYqH6M4 https://cassyni.com/events/Ng4djkTVWJmArUXv31iePf?videoPreview=1 Co-orbital asteroids of terrestrial planets affected by the von Zeipel–Lidov–Kozai mechanism, Analyzing collision probability for asteroids detected on too short arcsnohttps://cassyni.com/events/Ng4djkTVWJmArUXv31iePf?videoPreview=12026-05-18T13:00:00+00:003463.24Celestial Mechanics and Dynamical AstronomyTwo distinct studies are presented. The first investigated the influence of the von Zeipel–Lidov–Kozai (ZLK) mechanism on co-orbital asteroids of terrestrial planets. A survey of known Venus, Earth, and Mars co-orbitals, using orbital integrations and a clone-based statistical approach, identified ZLK states. No pure ZLK states were found for Venus co-orbitals, though 2020 TV10, a Venus co-orbital, poses a potential Earth impact risk. For Earth, 17 new ZLK librators were identified, including 2012 FC71 and 2021 VU12 librating around 0°, and 2008 WM64, 2019 NC1, 2020 DX1, and 2022 UO10 around 180°. Asteroid 2016 CA138 may librate around 270°. These ZLK states provide dynamical protection from close Earth encounters. For Mars, 2017 XG62, a quasi-satellite, is the only known co-orbital librating around 90°, a high-inclination ZLK state that insulates it from encounters with other terrestrial planets. The second study developed an improved method for analyzing collision probability for asteroids detected on too-short observational arcs (TSAs). This approach combines the admissible region method with differential algebra (DA) and automatic domain splitting (ADS) for managing orbital uncertainties. The admissible state region is systematically partitioned, with orbital parameters and close-encounter distances represented by Taylor expansions for continuous, high-precision uncertainty propagation. The method effectively identifies regions of high collision probability and handles abrupt jumps in encounter time. Tests on past impactors like 2019 MO and 2008 TC3 demonstrated accurate impact probability calculations, which converge to nearly 100% with longer observation arcs. This framework offers a systematic and transparent assessment of impact risk for TSAs, proving valuable for imminent impactors with computational times typically ranging from 10 to 60 minutes.https://cassyni-user-files-prod.s3.amazonaws.com/S6h8ssYGVNBUtf8dYqH6M4 https://cassyni.com/events/TcYgCavjttJUJtpbY6n1oT/seminar/qa https://cassyni.com/slides/outline/TcYgCavjttJUJtpbY6n1oT https://cassyni.com/events/TcYgCavjttJUJtpbY6n1oT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JCLquybPfuum5KopqmbSFY https://cassyni.com/events/TcYgCavjttJUJtpbY6n1oT?videoPreview=1 Infinite convex geometries with lower semi-modularity and join semi-distributivitynohttps://cassyni.com/events/TcYgCavjttJUJtpbY6n1oT?videoPreview=12026-05-20T14:00:00+00:003933.84Logica UniversalisWe construct a class K of infinite convex geometries by taking unions of chains of finite convex geometries, and prove that every member of K is both lower semi-modular and join semi-distributive. These properties, while automatic in the finite case, can fail for infinite convex geometries in general. We also show that not all infinite convex geometries arise via this construction, so that K is a proper subclass of the class of all infinite convex geometries.https://cassyni-user-files-prod.s3.amazonaws.com/JCLquybPfuum5KopqmbSFY https://cassyni.com/slides/outline/Eo1ENQKkQwSPbUY7jA4UhT https://cassyni.com/events/Eo1ENQKkQwSPbUY7jA4UhT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/83TxzaQ9kuw7stWFWmAjeE https://cassyni.com/events/Eo1ENQKkQwSPbUY7jA4UhT?videoPreview=1 Synergies, next steps & plans for 2027nohttps://cassyni.com/events/Eo1ENQKkQwSPbUY7jA4UhT?videoPreview=12025-07-02T08:00:00+00:002760.68The seminar addressed critical advances and future directions in metascience, emphasizing its role in enhancing the effectiveness and integrity of scientific research globally. A key highlight was the presentation by the Ukrainian Deputy Minister of Education and Science, outlining Ukraine’s strategic reforms amid wartime challenges, including a nationwide assessment of over 600 research institutions using a British REF-inspired model. This evaluation incorporates 37 quantitative indicators and a 20% impact score reflecting economic and societal contributions, underpinning a new performance-based funding formula. Ukraine is also developing a national researcher evaluation system prioritizing STEM and early-career researchers, supported by a digital platform and an expert database including international reviewers, alongside measures to combat predatory publishing. Reflections from the UK Metascience Unit underscored the importance of embedding a culture of experimentation within funding systems to optimize outcomes such as speed, inclusivity, and impact, highlighting the growing prominence of AI in research evaluation and funding processes. The Metascience Alliance was introduced as a multi-stakeholder initiative fostering collaboration across researchers, funders, publishers, and service providers to accelerate systemic change through collective ideation and experimentation. Looking ahead, the next Metascience Conference is scheduled for June 2027 in Montreal, hosted by the Tenenbaum Open Science Institute, aiming to build on current momentum with a focus on diversity, openness, and evidence-informed reform. Interim engagement opportunities include the 2026 World Conference on Research Integrity in Vancouver, which shares overlapping themes and emphasizes inclusivity and early-career support. Together, these efforts signify a transition of metascience from corrective measures toward creative re-imagination of scientific practice.https://cassyni-user-files-prod.s3.amazonaws.com/83TxzaQ9kuw7stWFWmAjeE https://cassyni.com/events/Rdyt8UrXYR1omRLYnWzMFj/seminar/qa https://cassyni.com/slides/outline/Rdyt8UrXYR1omRLYnWzMFj https://cassyni.com/events/Rdyt8UrXYR1omRLYnWzMFj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9RFbDnv1njwexYxFkoaHVY https://cassyni.com/events/Rdyt8UrXYR1omRLYnWzMFj?videoPreview=1 Five Editions Later: The Evolution and Impact of Analytical Mechanics of Space Systemsnohttps://cassyni.com/events/Rdyt8UrXYR1omRLYnWzMFj?videoPreview=12026-08-05T17:00:00+00:003346.28AIAAJoin NAE member and AIAA Fellow Hanspeter Schaub as he reflects on the journey behind Analytical Mechanics of Space Systems, one of the leading textbooks in spacecraft dynamics and control. In this interview, Schaub discusses the origins of the book, how it has evolved through five editions, and the changing needs of aerospace education over nearly three decades. Topics include the enduring importance of analytical mechanics, the integration of modern spacecraft applications, and the book’s impact on students, educators, and practicing engineers worldwide. Topics include the intersection of theory and simulation, the growing importance of autonomy and multi-spacecraft systems, and why a strong foundation in analytical mechanics remains essential for tackling the challenges of future space missions.https://cassyni-user-files-prod.s3.amazonaws.com/9RFbDnv1njwexYxFkoaHVY https://cassyni.com/slides/outline/KDcGkrUUeBfcumo7QrNZC9 https://cassyni.com/events/KDcGkrUUeBfcumo7QrNZC9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EwLNvCJooRY2Se6gnyqFhx https://cassyni.com/slides/outline/7rhNh8bQYevddXoy3rvnBF https://cassyni.com/events/7rhNh8bQYevddXoy3rvnBF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JPQ2fboDfy9noJEmxBjr8N https://cassyni.com/events/PBJKBevdQLmUuy7PfY7Pgq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/S4B7Krc7XqobV65ZxKP4Ue https://cassyni.com/slides/outline/DnZVbDuN2EMMYGxTNzSvdB https://cassyni.com/events/DnZVbDuN2EMMYGxTNzSvdB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/91jDdqzs8eDb8KheE9z1NN https://cassyni.com/events/DnZVbDuN2EMMYGxTNzSvdB?videoPreview=1 Georgia Tech Panel on Climate Actionnohttps://cassyni.com/events/DnZVbDuN2EMMYGxTNzSvdB?videoPreview=12023-03-13T09:00:00+00:003029.76 School of Public PolicyThis seminar addresses the critical challenge of climate change within the broader framework of the United Nations Sustainable Development Goals, emphasizing the urgency of limiting global temperature rise amid growing energy demands worldwide. The discussion integrates multidisciplinary perspectives on envisioning a sustainable future by 2050, focusing on urban design, energy systems, business models, and policy frameworks. Urban planning experts highlight the necessity of dense, green cities that mitigate heat island effects through strategic tree canopy infrastructure and adaptive land use, while acknowledging the complexities of accommodating population growth and climate-driven migration. Energy specialists project a transition from predominantly fossil-fuel-based systems to a distributed, renewable-dominant grid featuring wind, solar, and electrification of end uses, coupled with carbon capture technologies. Business scholars anticipate transformative shifts toward sustainable business models that align profitability with environmental and social impact, emphasizing supply chain transparency, circularity, and decarbonization. Policy and social science insights underscore the importance of consumer education, equitable technology ownership, and market realignment to overcome systemic barriers. The panel collectively stresses the role of integrated technological innovation, social engagement, and interdisciplinary education in driving this transition. Georgia Tech’s contributions are noted in pioneering urban green infrastructure, fostering sustainability-focused entrepreneurship, and advancing multidisciplinary research and policy education. The seminar concludes with a call for students to cultivate broad problem-framing skills, embrace risk-taking, and build collaborative networks to effectively participate in shaping a resilient, low-carbon future.https://cassyni-user-files-prod.s3.amazonaws.com/91jDdqzs8eDb8KheE9z1NN https://cassyni.com/slides/outline/AL2GGSNgx2UiWaetjL4y6M https://cassyni.com/events/AL2GGSNgx2UiWaetjL4y6M/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TddVU6FDWBWeFwRG5rA98r https://cassyni.com/events/AL2GGSNgx2UiWaetjL4y6M?videoPreview=1 On knowing what the facts are: A very brief history of epistemology and its political implicationsnohttps://cassyni.com/events/AL2GGSNgx2UiWaetjL4y6M?videoPreview=12022-05-30T08:00:00+00:002900.84 School of Public PolicyThis seminar addresses the increasing contestation of facts in contemporary democratic societies and explores the philosophical discipline of epistemology as a means to understand and potentially stabilize political discourse. It provides a historical overview of epistemology, emphasizing its relevance to political polarization, declining trust in science, and the proliferation of conspiracy theories. The analysis critiques three common assumptions about facts: that they are directly given by observation, prior to and independent of theory, and constitute a firm foundation for scientific knowledge. Drawing on classical and modern philosophy—from Plato’s definitions of knowledge, through Aristotle’s and Parmenides’ contrasting views on perception, to Hume’s problem of induction and Kant’s transcendental idealism—the discussion reveals inherent limits to knowing facts with absolute certainty. The seminar highlights Charles Sanders Peirce’s evolutionary epistemology and pragmatism, which frames knowledge as fallible and evolving through self-correcting inquiry, linking epistemic practices with ethical norms. It concludes by proposing twelve ethical norms for public deliberation, including transparency, equal access, honesty, critical assessment, and civility, as essential for democratic engagement with contested facts. The seminar underscores that no singular authority determines facts; rather, facts emerge through reasoned, critical, and ethically guided deliberation, which is crucial for sustaining democratic institutions amid polarization and epistemic uncertainty.https://cassyni-user-files-prod.s3.amazonaws.com/TddVU6FDWBWeFwRG5rA98r https://cassyni.com/slides/outline/MCKBQ7881TavBLBKdSF6fo https://cassyni.com/events/MCKBQ7881TavBLBKdSF6fo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CDdagPXgb2mYnqDTSsRQnr https://cassyni.com/events/MCKBQ7881TavBLBKdSF6fo?videoPreview=1 AI in Medical Education Selection: AAMC’s Toolkit for Responsible Implementationnohttps://cassyni.com/events/MCKBQ7881TavBLBKdSF6fo?videoPreview=12025-04-01T08:00:00+00:003682.96AAMCThe AAMC, in collaboration with its Technical Advisory Committee, developed [a toolkit](https://www.aamc.org/about-us/mission-areas/medical-education/artificial-intelligence-resources-admission-and-selection-processes) to support medical schools and residency programs in responsibly integrating AI into their admissions and selection processes. This webinar introduces the toolkit and provides guidance on applying the AAMC’s [Principles for Responsible AI in Medical School and Residency Selection](https://www.aamc.org/about-us/mission-areas/medical-education/principles-ai) to ensure fairness, transparency, and accountability. This webinar is part of the Artificial Intelligence in Academic Medicine Webinar Series, hosted by the AAMC. It explores critical concepts, the current landscape, and practical strategies drawn from various perspectives and institutions to support you in navigating the evolving world of AI in academic medicine. For more information, see [the complete series webpage](https://www.aamc.org/about-us/mission-areas/medical-education/artificial-intelligence-ai-academic-medicine-webinar-series). https://cassyni-user-files-prod.s3.amazonaws.com/CDdagPXgb2mYnqDTSsRQnr https://cassyni.com/slides/outline/PfZCdXMkCkMQYGetB89jPj https://cassyni.com/events/PfZCdXMkCkMQYGetB89jPj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Wo91VKU63AS4a63vj2hzNA https://cassyni.com/events/PfZCdXMkCkMQYGetB89jPj?videoPreview=1 Will the Internet Fragmentnohttps://cassyni.com/events/PfZCdXMkCkMQYGetB89jPj?videoPreview=12017-06-06T08:00:00+00:005118.96 School of Public PolicyThe discourse on Internet fragmentation reframes the issue as a fundamental tension between the global, borderless nature of digital communication and the territorially bounded sovereignty of nation-states. This tension manifests in state-driven efforts to assert control through content filtering, data localization, and preferential use of domestic technology providers, reflecting a broader power struggle over governance authority in cyberspace. The analysis critiques the prevailing assumption that national sovereignty is the sole legitimate framework for Internet governance, advocating instead for novel, transnational governance models that recognize the Internet as a globally interconnected polity. Empirical observations highlight the evolving roles of diverse actors—including states, multinational corporations, civil society, and technical communities—in shaping governance outcomes. Industry-led initiatives, such as Microsoft’s Digital Geneva Convention and proposals for a stateless attribution council, exemplify emerging multi-stakeholder approaches addressing cybersecurity and accountability. The discussion underscores the complexity of aligning divergent cultural, political, and legal perspectives on data privacy, security, and human rights across jurisdictions. It emphasizes pragmatic, issue-specific coalitions as pathways toward incremental governance innovation, rather than grand institutional redesigns. Key challenges include balancing governmental authority with corporate accountability, ensuring transparency and redress mechanisms, and fostering global legitimacy amid geopolitical contestation. Ultimately, the analysis situates human rights as a tangible normative foundation for governance, advocating for adaptive frameworks that limit collective decision-making to essential domains while enabling private and market-driven innovation. This nuanced perspective informs ongoing debates on the future architecture of Internet governance and the preservation of an open, secure, and rights-respecting digital environment.https://cassyni-user-files-prod.s3.amazonaws.com/Wo91VKU63AS4a63vj2hzNA https://cassyni.com/slides/outline/LD1yJjq58YUmWaMKXTmmru https://cassyni.com/events/LD1yJjq58YUmWaMKXTmmru/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UKtzFuETqsfctNLb6Sh5vW https://cassyni.com/events/LD1yJjq58YUmWaMKXTmmru?videoPreview=1 Women's Leadership Panelnohttps://cassyni.com/events/LD1yJjq58YUmWaMKXTmmru?videoPreview=12019-05-21T08:00:00+00:005276.16 School of Public PolicyThis seminar explores women’s leadership within the context of a large research university, focusing on professional growth, leadership development, and work-life integration. Panelists from diverse administrative and academic roles at Georgia Tech share experiential insights on navigating complex institutional structures, leveraging transferable skills, and pursuing continuous professional development through courses and networking opportunities. Emphasis is placed on assertiveness in applying new skills, intentionality in training, and the importance of sponsorship and mentorship for career advancement. Challenges discussed include managing public scrutiny, transitioning from peer to supervisor, and overcoming gender and racial biases, with strategies such as transparency, trust-building, and standing firmly in one’s professional identity. The panel highlights the non-linear nature of career trajectories, encouraging risk-taking and resilience in the face of uncertainty and failure. Work-life integration is addressed candidly, acknowledging the fluid and dynamic balance between professional responsibilities and personal commitments, with self-care and prioritization identified as critical components. The discussion underscores the significance of supportive relationships both at work and home, and the role of leadership in modeling excellence and fostering development in others. Practical advice includes volunteering to gain experience, engaging in leadership programs, and cultivating honest self-assessment to align career paths with personal values and strengths. The seminar concludes by affirming the value of community and ongoing dialogue in empowering women leaders within higher education.https://cassyni-user-files-prod.s3.amazonaws.com/UKtzFuETqsfctNLb6Sh5vW https://cassyni.com/slides/outline/WadfH6R6MA7C35eTYZifYR https://cassyni.com/events/WadfH6R6MA7C35eTYZifYR/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RypNHeuikx39wgBog95aqU https://cassyni.com/events/WadfH6R6MA7C35eTYZifYR?videoPreview=1 Work Supports and Health: The Minimum Wagenohttps://cassyni.com/events/WadfH6R6MA7C35eTYZifYR?videoPreview=12020-04-23T08:00:00+00:004357.24 School of Public PolicyThis seminar examines the impacts of minimum wage policies on health and well-being, with a focus on low-income workers, particularly women and families. The analysis draws on state-level variation in minimum wage laws and earned income tax credits (EITC) to assess effects on mortality, child maltreatment, and economic conditions. Using individual-level mortality data from the CDC, one study finds that increases in minimum wage and EITC are associated with significant reductions in non-drug suicide deaths—approximately 3% and 4.8% decreases per 10% policy increase—while showing no short-term effect on drug overdose deaths. These findings suggest that income support policies may mitigate suicide risk, especially during economic crises such as the COVID-19 pandemic. Complementary research employing longitudinal data from the Fragile Families and Child Well-being Study reveals that a $1 increase in the minimum wage correlates with a 10% reduction in spanking and substantial declines in physical (24%) and psychological aggression (12%) among children aged 3 to 9, though no significant effects on neglect or household income were observed. Mechanisms include reduced parental employment and fewer evening work shifts, alongside decreased externalizing behaviors in children. Policy analysis highlights the urgency of raising wages amid the COVID-19 recession, emphasizing the disproportionate impact of low wages on women of color in frontline jobs and the necessity of continuing phased minimum wage increases and premium pay initiatives. Collectively, these findings underscore the health and social benefits of pro-worker wage policies and their critical role in addressing economic and racial inequities exacerbated by the pandemic.https://cassyni-user-files-prod.s3.amazonaws.com/RypNHeuikx39wgBog95aqU https://cassyni.com/slides/outline/X5HGKn4cncfF2rBM911Toj https://cassyni.com/events/X5HGKn4cncfF2rBM911Toj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WReohojSi522zZqpFyiKjk https://cassyni.com/events/X5HGKn4cncfF2rBM911Toj?videoPreview=1 Panel Discussion: The Rise of Fake Newsnohttps://cassyni.com/events/X5HGKn4cncfF2rBM911Toj?videoPreview=12017-03-16T09:00:00+00:005671.0 School of Public PolicyThis panel discussion critically examines the multifaceted phenomenon of fake news, exploring its definitions, origins, and implications within contemporary media landscapes. The discourse highlights fake news as encompassing both deliberately fabricated content aimed at financial gain through clickbait and ideologically driven narratives that challenge dominant media discourses. Emphasis is placed on the inherent biases present in mainstream media, shaped by institutional power and national interests, as well as the ideological biases of media consumers themselves. The panelists underscore the role of alternative media and international outlets, such as RT.com, in providing counter-narratives that complicate traditional understandings of truth and propaganda. The discussion also addresses the rhetorical deployment of “fake news” as a tool to discredit opposing viewpoints, particularly in political contexts. A significant focus is placed on media literacy, with recognition of widespread difficulties among younger populations in discerning credible information, exacerbated by the rapid evolution of digital media and social platforms. The panel advocates for enhanced critical and computational literacy integrated into educational curricula, emphasizing the need for metacognitive approaches to media consumption that account for both front-end content and back-end algorithmic influences. Practical strategies for navigating information overload include triangulating multiple sources across the political spectrum and maintaining skepticism toward emotionally charged content. The conversation concludes by acknowledging the destabilizing effects of fragmented media ecosystems on democratic consensus, while affirming the ongoing necessity of critical engagement with diverse information sources in an era of pervasive misinformation.https://cassyni-user-files-prod.s3.amazonaws.com/WReohojSi522zZqpFyiKjk https://cassyni.com/slides/outline/Re9cpFwqxaaAdyw7Y61fpH https://cassyni.com/events/Re9cpFwqxaaAdyw7Y61fpH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Y2m272au8opMRn3vuyZ31Q https://cassyni.com/events/Re9cpFwqxaaAdyw7Y61fpH?videoPreview=1 Get Ready for Mixed World: Economic Factors Affecting IPv6 Deploymentnohttps://cassyni.com/events/Re9cpFwqxaaAdyw7Y61fpH?videoPreview=12019-05-17T08:00:00+00:001993.04 School of Public PolicyThis study examines the economic factors influencing the deployment of IPv6 amid the coexistence and competition with IPv4, focusing on the incentives shaping network operators’ transition decisions. The analysis draws on economic theories of network externalities and standards competition, emphasizing the role of dual stack operation and translation technologies in maintaining compatibility between incompatible protocols. Empirical data from APNIC measurements across 215 economies reveal heterogeneous IPv6 adoption patterns, with approximately 80% of countries showing minimal deployment, 12% exhibiting strong growth, and 8% plateauing at intermediate levels. Higher IPv6 adoption correlates with greater GDP per capita and less concentrated broadband and wireless markets, suggesting that wealthier, more competitive markets foster IPv6 investment. The study also highlights the impact of IPv4 address scarcity and rising secondary market prices, which incentivize IPv6 deployment primarily for network growth rather than immediate revenue gains. Modeling of operator scenarios demonstrates that large, fast-growing mobile networks with increasing IPv6 traffic ratios can reduce IPv4 address demand over time, whereas smaller or legacy enterprise networks derive limited economic benefit from IPv6 transition. Cloud service providers, facing slow enterprise IPv6 adoption, continue to acquire IPv4 addresses, reflecting persistent demand. Overall, the findings indicate that IPv6 deployment is economically rational for operators requiring growth and modernization, particularly in mobile sectors, while legacy and smaller networks may delay transition. This mixed-standard environment is likely to persist, with economic incentives shaping diverse adoption trajectories rather than a rapid, uniform shift.https://cassyni-user-files-prod.s3.amazonaws.com/Y2m272au8opMRn3vuyZ31Q https://cassyni.com/slides/outline/6Ns41biNqiyHsPtccnRN85 https://cassyni.com/events/6Ns41biNqiyHsPtccnRN85/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3jAFZQ8nQuyua3ZHAUtysc https://cassyni.com/events/6Ns41biNqiyHsPtccnRN85?videoPreview=1 Community Engagement and Undergraduate Social Responsibility Attitudesnohttps://cassyni.com/events/6Ns41biNqiyHsPtccnRN85?videoPreview=12021-07-15T08:00:00+00:001662.8 School of Public PolicyThis study investigates the development of undergraduate students’ social responsibility attitudes, particularly focusing on their perceived obligations to the public within personal and professional contexts. Conducted at Georgia Tech, a predominantly engineering and computing institution, the research addresses concerns that students’ commitment to public well-being diminishes over the course of their degree programs. Utilizing a mixed-methods design, the project follows a primary cohort of several thousand students who matriculated in Fall 2017, employing a modified, discipline-neutral survey adapted from the Professional Social Responsibility Development Model alongside qualitative interviews with a subset of approximately 20 students at two time points. Survey data collected at entry, midpoint, and near graduation assess changes in social responsibility attitudes and the influence of various community engagement activities—both discipline-based and peer-based—on these attitudes. Preliminary findings indicate that students’ social responsibility attitudes remain stable or slightly decline over time, with salary considerations increasingly prioritized over helping others. Female students exhibit consistently higher social responsibility scores than male students, though both groups follow parallel trajectories. Qualitative analysis reveals a distinction between micro-level (individual) and macro-level (organizational) conceptions of responsibility, with personal commitments not consistently translating into professional ethical obligations. Notably, discipline-based community engagement appears to support professional responsibility development, while peer-based engagement positively influences overall social responsibility scores, especially among non-white students. These insights underscore the complex dynamics shaping ethical attitudes in STEM undergraduates and suggest targeted community engagement may bolster professional social responsibility.https://cassyni-user-files-prod.s3.amazonaws.com/3jAFZQ8nQuyua3ZHAUtysc https://cassyni.com/slides/outline/3ud2nBUkeSCkqEeq9zd17s https://cassyni.com/events/3ud2nBUkeSCkqEeq9zd17s/abstract https://cassyni-user-files-prod.s3.amazonaws.com/L6PQbgzG2pD8zJyacqVt5C https://cassyni.com/events/3ud2nBUkeSCkqEeq9zd17s?videoPreview=1 Mirror diffusion of cosmic rays in MHD turbulencenohttps://cassyni.com/events/3ud2nBUkeSCkqEeq9zd17s?videoPreview=12024-02-01T06:00:00+00:002542.68Journal of Plasma PhysicsDiffusion of cosmic rays (CRs) in magnetized and turbulent plasmas is a long-standing and challenging problem. The recent explosive interest in understanding CR diffusion arises from its broad impacts on plasma physics, space physics, and astrophysics. However, the existing CR diffusion theories in general face severe difficulties when explaining new-generation CR observations, making it more urgent to reexamine the CR diffusion mechanisms. Very recently, the progresses in understanding and modeling MHD turbulence lead to intense research effort toward a paradigm shift of CR diffusion. In this talk, I will focus on one of the new diffusion mechanisms, the mirror diffusion, which is induced by large-scale magnetic compressions, i.e., magnetic mirrors, in MHD turbulence. I will present its basic physical picture, our theoretical predictions on the diffusion behavior, and our numerical testing with test particle simulations. I will also briefly discuss its implications on astrophysical observations and the IBEX Ribbon. https://cassyni-user-files-prod.s3.amazonaws.com/L6PQbgzG2pD8zJyacqVt5C https://cassyni.com/slides/outline/GFq8wGesct3ciute8MBjG1 https://cassyni.com/events/GFq8wGesct3ciute8MBjG1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Cd42tsFfnMQpExPy9JLJYn https://cassyni.com/events/GFq8wGesct3ciute8MBjG1?videoPreview=1 Dusty plasmas under weightlessnessnohttps://cassyni.com/events/GFq8wGesct3ciute8MBjG1?videoPreview=12024-03-28T06:00:00+00:003071.96Journal of Plasma PhysicsDusty (complex) plasmas provide a fascinating system to study fundamental processes in many-particle systems since the (dust) particles can be imaged and followed on the kinetic individual-particle level. Gravity is often a major problem when experimenting with dusty plasmas since, on Earth, larger dust clouds are compressed to the lower edge of the plasma. We have performed experiments on parabolic flights without the influence of the disturbing force of gravity where we have measured the dust motion in three dimensions by stereoscopic techniques. This makes new properties of the dust-plasma system accessible for measurements, such as self-excited waves, forces at the dust boundary or the dynamics of phase separation. Moreover, I will present the planned multi-user facility for complex plasma experiments COMPACT on the ISS.https://cassyni-user-files-prod.s3.amazonaws.com/Cd42tsFfnMQpExPy9JLJYn https://cassyni.com/events/LhhCU3zUyMxbLLvgHQW5GH/seminar/qa https://cassyni.com/slides/outline/LhhCU3zUyMxbLLvgHQW5GH https://cassyni.com/events/LhhCU3zUyMxbLLvgHQW5GH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FftviJpvXE9nUFrEVVPNAr https://cassyni.com/events/LhhCU3zUyMxbLLvgHQW5GH?videoPreview=1 REACH Casual Friday: Engagement & Introductionsnohttps://cassyni.com/events/LhhCU3zUyMxbLLvgHQW5GH?videoPreview=12025-10-24T17:00:00+00:001208.56Research Evaluation and Analytics Capacity Hub## This month's Casual Friday Topic: Engagement throughout the REACH Network and Get to Know your Colleagues! In our REACH Casual Friday events we aim to gather virtually with network participants, especially those participating in RAMP. The first 30-minutes will be a focused presenter and topic followed by more causal networking and possible break-out rooms.https://cassyni-user-files-prod.s3.amazonaws.com/FftviJpvXE9nUFrEVVPNAr https://cassyni.com/slides/outline/U7RGAJhMZEGRpvT9FHMogH https://cassyni.com/events/U7RGAJhMZEGRpvT9FHMogH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/MePBvtc8SoPuwf7gv7A38S https://cassyni.com/events/U7RGAJhMZEGRpvT9FHMogH?videoPreview=1 Complexity reduction in the solution of parametrized PDEsnohttps://cassyni.com/events/U7RGAJhMZEGRpvT9FHMogH?videoPreview=12025-10-16T19:00:00+00:003234.84AI Institute in Dynamic SystemsSolving differential problems using full order models (FOMs), such as the finite element method, usually results in prohibitive computational costs, particularly in real-time simulations and multi-query routines. Reduced order modeling aims to replace FOMs with reduced order models (ROMs) characterized by much lower complexity but still able to express the physical features of the system under investigation. Within this context, deep learning-based reduced order models (DL-ROMs) have emerged as a novel and comprehensive approach, offering efficient and accurate surrogates for solving parametrized time-dependent nonlinear PDEs. By leveraging both the mathematical properties and physical knowledge of the system, the accuracy and generalization capabilities of DL-based ROMs can be further enhanced. Building on this motivation, two main approaches to reduced order modeling of parametrized PDEs are introduced: latent dynamics models (LDMs) and pre-trained physics-informed DL-ROMs (PTPI-DL-ROMs).https://cassyni-user-files-prod.s3.amazonaws.com/MePBvtc8SoPuwf7gv7A38S https://cassyni.com/slides/outline/6sYHAusngYT7hATyNj9fXT https://cassyni.com/events/6sYHAusngYT7hATyNj9fXT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/88AYj45pqdaAsxVMPouBBt https://cassyni.com/events/6sYHAusngYT7hATyNj9fXT?videoPreview=1 The psychology and politics of conspiracy theoriesnohttps://cassyni.com/events/6sYHAusngYT7hATyNj9fXT?videoPreview=12021-10-27T06:00:00+00:003358.68Part of the nonprofit Annual Reviews organizationConspiracy theories played a role in the insurrection at the US Capitol in January and continue to fuel resistance, in some circles, to getting vaccinated for Covid-19. It may seem like conspiracy theories are more prevalent now than ever, and more common on the political right than on the left — but are they really? Recent research suggests that no one is totally immune. That’s because conspiracy theories tap into fundamental aspects of human psychology, helping to explain why they’re so alluring —and so hard to dispel once they take hold. Researchers are trying to develop ways to disrupt their influence on our minds and our society.https://cassyni-user-files-prod.s3.amazonaws.com/88AYj45pqdaAsxVMPouBBt https://cassyni.com/events/7NBtDbXK811AgvzryASTnm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UkRpAT2LsoiLf2h7mQ7j6v https://cassyni.com/slides/outline/w4Ei5QYHxv6J4kdNFSfoK https://cassyni.com/events/w4Ei5QYHxv6J4kdNFSfoK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7AQavK8X7ZQttLtLWEQCnS https://cassyni.com/events/w4Ei5QYHxv6J4kdNFSfoK?videoPreview=1 Earth's rotational variations and their connection to core flowsnohttps://cassyni.com/events/w4Ei5QYHxv6J4kdNFSfoK?videoPreview=12024-11-07T06:00:00+00:002881.0Leeds Institute for Fluid DynamicsChanges in the Earth's rotation originate mostly from torques by the atmosphere and oceans, with a relatively small contribution from the Earth's core. The angular momentum exchange between core and mantle is however a long-standing problem. In this talk I will describe some of the mechanisms potentially at play and how they can be used to infer key properties of the core-mantle boundary. I will focus in particular on torsional Alfvén eigenmodes. The energy in these modes is equal parts magnetic and kinetic, and their motion is mostly columnar. The latter property has been used in the past to build approximate inviscid 1-D models. We have built a 3-D numerical model including viscosity, an electrically conductive inner core, and a thin, electrically conductive layer at the bottom of the mantle allowing the outer core to exchange angular momentum with the solid inner core and the mantle. I will present a systematic study the most relevant properties of these modes, particularly their columnarity, their torques, and their lifetimes as functions of the magnetic diffusivity and viscosity of the outer core, as well as functions of the electrical conductance of the bottom of the mantle.https://cassyni-user-files-prod.s3.amazonaws.com/7AQavK8X7ZQttLtLWEQCnS https://cassyni.com/events/EHGLsAafGQkxBjzSLc1PwT/seminar/qa https://cassyni.com/slides/outline/EHGLsAafGQkxBjzSLc1PwT https://cassyni.com/events/EHGLsAafGQkxBjzSLc1PwT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Cog4sjUG3KJ5gLY17faGb8 https://cassyni.com/events/EHGLsAafGQkxBjzSLc1PwT?videoPreview=1 Call for Papers: Virtual Special Issue: PFAS Removal and Destructionnohttps://cassyni.com/events/EHGLsAafGQkxBjzSLc1PwT?videoPreview=12025-10-29T15:30:00+00:001565.8ElsevierThis webinar will introduce Water Research X’s virtual special issue on “PFAS Removal and Destruction.” This webinar will highlight the new research that is needed to address the global challenge of PFAS contamination of water resources. Relevant topics include new technologies for PFAS removal and destruction, management of PFAS waste streams, PFAS destruction and by-products, life cycle environmental impacts, and pilot-scale and demonstration studies. Speakers and Guest Editors: Dr. Kyle Doudrick, University of Notre; Dr. Mei Sun, University of North Carolina at Charlotte; Dr. Hooman Vatankhah, Florida International University. Moderator: Dr. Treavor Boyer, Arizona State Universityhttps://cassyni-user-files-prod.s3.amazonaws.com/Cog4sjUG3KJ5gLY17faGb8 https://cassyni.com/slides/outline/GkWN6apHThXSYgTztHv2fP https://cassyni.com/events/GkWN6apHThXSYgTztHv2fP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Vic7gdhweHmWpX1pMBcAmC https://cassyni.com/events/GkWN6apHThXSYgTztHv2fP?videoPreview=1 Are AI Risks Insurable?nohttps://cassyni.com/events/GkWN6apHThXSYgTztHv2fP?videoPreview=12025-09-26T01:00:00+00:00983.04Risk Sciences[***Risk Sciences***](https://www.keaipublishing.com/en/journals/risk-sciences/) aims to foster diverse, multidisciplinary insights in risk sciences, bridging theory and practice through a series of academic activities. Runhuan Feng is a Chair Professor in the School of Economics and Management at Tsinghua University. He is a Fellow of the Society of Actuaries and a Chartered Enterprise Risk Analyst. Prior to joining Tsinghua, he was a tenured Professor, the State Farm Companies Foundation Endowed Professor at the University of Illinois at Urbana-Champaign, the Faculty Lead for the Finance and Insurance sector at the Discovery Partnership Institute of the University of Illinois System. He is currently serving as the Executive Editor-in-Chief for Risk Sciences. This speech record is an excerpt from Professor Feng's keynote speech for the [Risk Sciences Colloquium – Artificial Intelligence and Risk Management](https://www.keaipublishing.com/en/journals/risk-sciences/event/risk-sciences-colloquium-artificial-intelligence-and-risk-management/), which was held on September, 26, 2025, in Beijing, China.https://cassyni-user-files-prod.s3.amazonaws.com/Vic7gdhweHmWpX1pMBcAmC https://cassyni.com/slides/outline/9LnJQL7QsqDvneH6L8JQDK https://cassyni.com/events/9LnJQL7QsqDvneH6L8JQDK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/P2xtVLM31cQuPYGA1hrjbU https://cassyni.com/events/9LnJQL7QsqDvneH6L8JQDK?videoPreview=1 AI Modeling of Expert Preferences in Freeform Structural Optimizationnohttps://cassyni.com/events/9LnJQL7QsqDvneH6L8JQDK?videoPreview=12025-09-17T07:00:00+00:002844.0ArtIStE - Artificial Intelligence in Structural EngineeringThe building and construction industry is a significant source of greenhouse gas emissions. The quantities of structural materials used globally correspond to approx. 10% of the annual carbon emissions. Reducing the embodied carbon of new construction is needed, especially considering the predicted population growth and urbanization. Recommended strategies include using more environmentally friendly materials and/or structural optimization. Topology optimization is a promising design method in this context since the resulting designs often significantly outperform conventional lowweight designs. It is a computational approach that generates efficient material layouts tailored to a user’s specific design requirements. To take full advantage of its exploratory power, topology optimization leaves the user as a passive observer who initiates the design process and assesses the quality of the design upon completion. The resulting structural designs are typically high-performing and have high levels of geometric complexity. However, ensuring the physical performance is adequately predicted by a fully automated design approach requires including all relevant operating conditions, mechanical behaviors, and fabrication constraints. This talk will discuss different strategies to include relevant considerations for topology-optimized design of low-carbon civil structures, including methods that use AI to leverage human designers’ experiences.https://cassyni-user-files-prod.s3.amazonaws.com/P2xtVLM31cQuPYGA1hrjbU https://cassyni.com/slides/outline/QAG3uU33Svm1Bjgs8jiCi1 https://cassyni.com/events/QAG3uU33Svm1Bjgs8jiCi1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/L5c1EgATz5kaKGLYfMtZXU https://cassyni.com/events/QAG3uU33Svm1Bjgs8jiCi1?videoPreview=1 Arbuscular mycorrhizal fungi foraging strategies, decision making and interactions in soil chips.nohttps://cassyni.com/events/QAG3uU33Svm1Bjgs8jiCi1?videoPreview=12025-08-04T13:45:00+00:00919.4NoneThe objective of this project is to determine how fungi can make decisions across scales that benefit the whole mycelial body and whether symbiotic interactions with plants can modify fungal decision making. To answer these questions, we are using microfluidic chips, also called soil chips, to design physical and chemical challenges for the mycelium. The hyphal behavior is examined in diverse nutritional and symbiotic contexts by using different culture  and plant-host systems such as inoculated carrot root organ culture, inoculated *Marchantia paleacea*, or without a host, grown in a myristate medium. The micrometer scale of the chip enables us to observe the growth patterns of individual hyphae as well as subcellular processes, providing insights into how fungal hyphae respond to various environmental cues. This experimental configuration is also used to examine the mycorrhizal interaction at a larger scale by facilitating documentation of the mycelium's architectural features and allowing us to monitor resource allocation within the mycelium. Additionally, we have been able to observe and document mycelial development and anastomosis formation as well as monitor the ability of the mycelium to establish novel symbiotic interactions or maintain existing ones in diverse environments.https://cassyni-user-files-prod.s3.amazonaws.com/L5c1EgATz5kaKGLYfMtZXU https://cassyni.com/events/VbPhQz9pGxrQK9Gf9Mx6fP/seminar/qa https://cassyni.com/slides/outline/VbPhQz9pGxrQK9Gf9Mx6fP https://cassyni.com/events/VbPhQz9pGxrQK9Gf9Mx6fP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/MmYbC4X1ZAXz38CgxbLu3c https://cassyni.com/events/VbPhQz9pGxrQK9Gf9Mx6fP?videoPreview=1 Optimal sampling and extreme-event aware learning for probabilistic modeling of extremes in complex systemsnohttps://cassyni.com/events/VbPhQz9pGxrQK9Gf9Mx6fP?videoPreview=12025-11-13T20:00:00+00:003560.56AI Institute in Dynamic SystemsAnalysis of real-world physical and engineering systems is characterized by unique computational challenges associated with high dimensionality of parameter spaces, large cost of simulations or experiments, as well as existence of uncertainty. For a wide range of these problems the goal is to either quantify uncertainty and compute risk for critical events, optimize parameters or control strategies, and/or making decisions. In this talk we will discuss two aspects related to the modeling of extreme events: i) optimal sampling of data for the characterization of extreme events, and ii) extreme-event aware learning, i.e. learning methods that do not necessarily assume the existence of extreme events in the training data. In the first part of the talk, we will discuss how Bayesian active learning provides a flexible framework for i) identifying the most informative data for extremes, which is relevant for engineering problems where optimal experimental design is feasible, or ii) quantify the value of data in a prescribed dataset, e.g. relevant for climate modeling. Despite its attractive properties, the Bayesian framework is often prohibitively expensive in terms of the required simulations or experiments, even in the active learning setting. We introduce a new class of acquisition functions that utilize a likelihood-weighted ratio that accounts for the importance of the output relative to the input. This ratio acts essentially as a probabilistic sampling weight and guides the sampling algorithm towards regions of the input space where the objective function assumes abnormal values, resulting in significant savings of computational or experimental resources needed for convergence. We show that the adopted acquisition functions can be rigorously derived as the asymptotic limit of an optimal acquisition function that has a minimax form over a functional space. Subsequently, we demonstrate their favorable properties compared to standard methods on benchmark functions commonly used in the optimization community as well as real world applications involving turbulence, fluid-structure interaction problems and optimal sensor placement. In the second part of the talk, we examine the problem of learning for extremes without the assumption of extreme events in the training data. We introduce the framework of Extreme Event Aware (e2a or eta) or $\eta$-learning which does not assume the existence of extreme events in the available data. $\eta$-learning reduces the uncertainty even in `unchartered' extreme event regions, by enforcing the extreme event statistics of a few observables during training, which can be available or assumed through qualitative arguments or other forms of analysis. This type of statistical regularization results in models that fit the observed data, but also enforces consistency with the prescribed or assumed statistics of some observables, enabling the generation of unprecedented extreme events even when the training data lack extremes therein. A series of theoretical results based on optimal transport theory offers a rigorous justification and highlights the optimality of the introduced method. The favorable properties $\eta$-learning are demonstrated in synthetic examples as well as a real world example involving modeling extreme precipitation events.https://cassyni-user-files-prod.s3.amazonaws.com/MmYbC4X1ZAXz38CgxbLu3c https://cassyni.com/slides/outline/S8rU6Cd9CkymHSy6Vha98Z https://cassyni.com/events/S8rU6Cd9CkymHSy6Vha98Z/abstract https://cassyni-user-files-prod.s3.amazonaws.com/F6hoHPTzHVU2KhdJGaFG8E https://cassyni.com/events/S8rU6Cd9CkymHSy6Vha98Z?videoPreview=1 Safeguarding Research: The Role of Academic Publishers in an Era of Political and Public Pressurenohttps://cassyni.com/events/S8rU6Cd9CkymHSy6Vha98Z?videoPreview=12026-01-13T12:00:00+00:003583.16Academic Publishing in EuropeIn an era where research increasingly faces political interference, threats to academic freedom, and widespread disinformation, the role of academic publishers extends far beyond traditional content dissemination. Publishers now serve as critical defenders of the integrity, accessibility, and credibility of scholarly knowledge—especially as researchers and institutions confront mounting pressures from authoritarian regimes, shrinking resources, and politicized narratives. This panel brings together experts from academic freedom advocacy, global access initiatives, and scholarly publishing to explore how publishers can uphold and advance these responsibilities in challenging contexts. * Dr. Ilyas Saliba will offer insights on protecting academic freedom and supporting researchers whose work is targeted by political or legal pressures. * Sarah Phibbs will discuss the vital role of equitable access to knowledge through initiatives like Research4Life, addressing how publishers can contribute to global research solidarity amid structural inequalities. * Louise Schouten will share strategies from the publishing industry perspective on safeguarding editorial independence, promoting transparency, and navigating ethical challenges in product development and peer review processes. Together, the panel will discuss how academic publishers can responsibly support open research, defend scholars under threat, combat misinformation, and ensure that scholarly communication remains a trusted foundation for knowledge—even in politically charged environments. This session invites publishers and stakeholders to consider their evolving role as proactive allies in safeguarding research for the public good across borders and political divides.https://cassyni-user-files-prod.s3.amazonaws.com/F6hoHPTzHVU2KhdJGaFG8E https://cassyni.com/slides/outline/Uc6VKcrmQ3kFePSf3PUmrV https://cassyni.com/events/Uc6VKcrmQ3kFePSf3PUmrV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Wnf2kc2A8dwnrKxVfC1qc2 https://cassyni.com/events/Uc6VKcrmQ3kFePSf3PUmrV?videoPreview=1 Open and Secure Research: Confronting uncomfortable truths about research openness, integrity and responsibility in global scholarshipnohttps://cassyni.com/events/Uc6VKcrmQ3kFePSf3PUmrV?videoPreview=12026-02-24T09:40:00+00:002424.32Researcher to ReaderWe must confront some uncomfortable truths. Openness does not necessarily equate to trust, and the ideals of open research do not guarantee integrity. Open and secure research requires us to rethink how we share knowledge and what we want research to be and not be. If we fail to define what we mean by science, research, and even the term ‘researcher,’ then we leave ourselves vulnerable – less grounded in evidence and more at the mercy of shifting opinions. As we look toward a trusted global research future, we must address two intertwined challenges: knowledge security and responsible internationalisation.https://cassyni-user-files-prod.s3.amazonaws.com/Wnf2kc2A8dwnrKxVfC1qc2 https://cassyni.com/slides/outline/Emwa2Uk57EEn1Cyx8i8N7f https://cassyni.com/events/Emwa2Uk57EEn1Cyx8i8N7f/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5YsvZAJ6fMHp8WsSLCSjux https://cassyni.com/events/Emwa2Uk57EEn1Cyx8i8N7f?videoPreview=1 Visualize This! Elevate Your Research with Better Postersnohttps://cassyni.com/events/Emwa2Uk57EEn1Cyx8i8N7f?videoPreview=12025-08-06T06:00:00+00:003312.88AAMCSharing your scholarship at regional, national, and international meetings is a key step in your professional development and in advancing the field of academic medicine. Often these presentations take the form of a scientific poster that recounts your research, innovation, or other scholarly work. Designing and presenting an engaging poster allows you to effectively share your work with an interested audience, receive valuable feedback, and network with others working on similar topics. In this video, speakers discuss strategies for designing an effective scientific poster and for successfully engaging with meeting attendees when presenting that poster. At the end of this webinar, attendees will be able to: (1) Describe the different purposes for presenting a poster (2) Identify strategies for designing an engaging, effective poster (3) Identify strategies for successfully engaging attendees at a poster session This webinar is part of the Scholarly Publishing Webinar Series, hosted by Academic Medicine and MedEdPORTAL. For more information on the complete series, see [aamc.org/publishingwebinar](https://www.aamc.org/about-us/mission-areas/medical-education/scholarly-publishing-webinar-series).https://cassyni-user-files-prod.s3.amazonaws.com/5YsvZAJ6fMHp8WsSLCSjux https://cassyni.com/slides/outline/FGbB5APbYgnpzyWqj9RANy https://cassyni.com/events/FGbB5APbYgnpzyWqj9RANy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TqDjzcue4dhXPky3gKqGmC https://cassyni.com/events/FGbB5APbYgnpzyWqj9RANy?videoPreview=1 Tuning droplet flow by fiber geometrynohttps://cassyni.com/events/FGbB5APbYgnpzyWqj9RANy?videoPreview=12025-11-19T09:00:00+00:003029.04The Edinburgh Fluid Dynamics Group (EFDG)Drops on fibrous structures play a crucial role in numerous industrial processes and applications. These include, but are not limited to, microfluidics, refrigeration coils, and textiles, as well as being omnipresent on slender structures in nature, grown by both plants and animals. In this talk, I will present how we can use fiber geometry to manipulate droplet flow. By altering a cylindrical fiber to a conical geometry, droplets not only self-propel but can also become independent coating units. By adding additional complexity through twists and softness to the fibers, I will demonstrate how this gives rise to a rich array of flow regimes that can actively manipulate fluid motion. These complex structures are shown to improve the collection of fog droplets in windy conditions and can, as such, provide new design parameters to enhance fog net technology. Fog nets are a simple technology used to harvest fresh water in arid regions of the world. When these twisted, spring-like structures are very soft, they can also passively actuate/compress due to capillarity, which can trap and transport liquid droplets.https://cassyni-user-files-prod.s3.amazonaws.com/TqDjzcue4dhXPky3gKqGmC https://cassyni.com/events/9qTXZeGpiehkc7Gc8ERNPX/seminar/qa https://cassyni.com/slides/outline/9qTXZeGpiehkc7Gc8ERNPX https://cassyni.com/events/9qTXZeGpiehkc7Gc8ERNPX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/YGHiTXabbBbqi5n6XjGfSe https://cassyni.com/events/9qTXZeGpiehkc7Gc8ERNPX?videoPreview=1 Using explainable AI to explore and control turbulent flowsnohttps://cassyni.com/events/9qTXZeGpiehkc7Gc8ERNPX?videoPreview=12026-05-27T10:00:00+00:003347.92Department of AeronauticsUnderstanding the skeleton underpinning turbulence has been an active research field for many decades. Traditionally, the study of turbulent flows has relied on heuristic coherent structures, i.e. observable flow features believed to be dynamically important, such as intense Reynolds-stress events or streak instabilities. In recent years, machine learning has provided new tools for studying turbulent flows (e.g. neural networks for flow prediction or reinforcement learning for flow control). However, many of these models remain black boxes, offering limited insights into the mechanisms underlying turbulence. In this talk I will introduce an explainable-deep-learning (XDL) methodology to identify features and define coherent structures in turbulence based on the most informative regions of the flow. The coherent structures identified through XDL are then compared to the classically defined coherent structures (e.g. Q events, streaks and vortices) to assess their relative importance in sustaining turbulent dynamics. Once the most important features sustaining turbulence are identified, I will show how they can be exploited through deep reinforcement learning (DRL) to reduce the drag. Remarkably, the control strategies discovered through the combination of XDL+DRL outperforms even models trained directly to reduce the drag, providing new pathways towards efficient control, which is a long-standing challenge in fluid dynamics with profound implications for energy systems, climate modeling and aerodynamics.https://cassyni-user-files-prod.s3.amazonaws.com/YGHiTXabbBbqi5n6XjGfSe https://cassyni.com/events/Y4fLm2uKscYfVnCqtiguJD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Ta3vBxhrsUrmNcUEzfUgYe https://cassyni.com/slides/outline/SdXhFWnZ3aTb6uxcHoh7Jm https://cassyni.com/events/SdXhFWnZ3aTb6uxcHoh7Jm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NPMbVv5R6zE78MpabWpZE6 https://cassyni.com/events/SdXhFWnZ3aTb6uxcHoh7Jm?videoPreview=1 Towards high-performance strategies for the integration of traditional CFD and ML strategiesnohttps://cassyni.com/events/SdXhFWnZ3aTb6uxcHoh7Jm?videoPreview=12026-01-29T17:00:00+00:003677.96AI Institute in Dynamic SystemsThe integration of machine learning (ML) with traditional computational fluid dynamics (CFD) is opening new directions for scalable, physics-aware simulation and control on modern high-performance computing platforms. Over the last three years, Dr. Lehmkuhl group efforts at BSC has focused on developing hybrid strategies that couple data-driven models with high-order CFD solvers to address challenges of accuracy, efficiency, and robustness in turbulent flow applications. A central thread of this research is the design of hybrid reduced-order modeling approaches that combine classical POD-based representations with deep learning architectures. By embedding POD coordinates into nonlinear latent spaces and augmenting them with neural closures, we extend reduced models beyond linear dynamics while preserving physical interpretability. This effort is closely linked to a Koopman-inspired framework, where β-Variational Autoencoders are employed to construct latent embeddings that promote near-linear evolution of complex turbulent flows. Together, these strategies enable robust low-dimensional forecasting, improved long-term stability, and enhanced generalization across regimes. Beyond modeling, a major thrust has been the tight coupling of CFD with deep reinforcement learning, with particular emphasis on the SOD2D framework. Through scalable, low-latency solver–agent integration, this work demonstrates how production-grade CFD codes can become learning-enabled platforms for active flow control and turbulence manipulation. Together, these developments outline a coherent vision for high-performance CFD–ML integration, bridging rigorous numerics and data-driven intelligence for next-generation simulation and digital-twin technologies.https://cassyni-user-files-prod.s3.amazonaws.com/NPMbVv5R6zE78MpabWpZE6 https://cassyni.com/events/MggZJVcnRJskPYWRHJ3CuB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GmuXJC2EtwcNTkaGzoULut https://cassyni.com/slides/outline/XZeeEAZHCTx5F4WSnroa37 https://cassyni.com/events/XZeeEAZHCTx5F4WSnroa37/abstract https://cassyni-user-files-prod.s3.amazonaws.com/G42L9AifqcTEpR5xuLpUJr https://cassyni.com/events/XZeeEAZHCTx5F4WSnroa37?videoPreview=1 SSP Innovation Showcase (Summer 2022)nohttps://cassyni.com/events/XZeeEAZHCTx5F4WSnroa37?videoPreview=12022-07-21T06:00:00+00:003646.36SSP Society for Scholarly PublishingA special, free webinar highlighting new and exciting industry innovations. Speakers present solutions or technology in seven-minute presentations, providing a unique opportunity to get a glimpse of the latest developments in the industry. Featuring Researcher, Straive, GT, Figshare, Morressier, Hum, and Atypon.https://cassyni-user-files-prod.s3.amazonaws.com/G42L9AifqcTEpR5xuLpUJr https://cassyni.com/slides/outline/U77QuP2c8G5SDNCt9CRcWH https://cassyni.com/events/U77QuP2c8G5SDNCt9CRcWH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QWCiWLqNcgC8cnDGSGnuNv https://cassyni.com/events/U77QuP2c8G5SDNCt9CRcWH?videoPreview=1 The Climate Challenge and Solutions for Communitiesnohttps://cassyni.com/events/U77QuP2c8G5SDNCt9CRcWH?videoPreview=12024-10-01T06:00:00+00:003350.16 School of Public PolicyMarilyn Brown delivered lecture "The Climate Challenge and Solutions for Communities" as one of the 2024 Rachel Carson Distinguished Anniversary Lecture Series on Oct 1. Abstract: The climate challenge and the recent paradigm shift in U.S. climate policy underscores the need for expedited energy and environmental system analysis at community scales: regions, states, and localities. An interdisciplinary team of academics, business leaders, and community organizations in the state of Georgia has developed a data-rich and analytically sophisticated approach that combines energy systems modeling with expert consultation and community engagement. Our down-selected top 20 climate solutions are diverse and impactful, and our approach is helping others. Dr. Marilyn Brown is a Regents Professor in the School of Public Policy at the Georgia Institute of Technology and a joint faculty member at Oak Ridge National Laboratory. Her research focuses on the design and impact of policies aimed at accelerating the development and deployment of sustainable energy technologies. Brown has led several energy technology and policy scenario studies and is a national leader in the analysis and interpretation of energy futures. Her 6 books include Climate Change and Global Energy Security (MIT Press), and she has written more than 250 journal articles. Currently she is focusing on equitable approaches to distributed solar and energy efficiency – coining the term “energy-efficiency gap” in 1990 and more recently quantifying the concept of “virtual power plants”. She contributed to the 2007 Intergovernmental Panel on Climate Change assessment reports for which the IPCC shared the 2007 Nobel Peace Prize. Her work has had significant visibility in the policy arena as evidenced by her briefings and testimonies before state and local legislative and regulatory bodies, Committees of both the U.S. House of Representatives and Senate, and international organizations. Dr. Brown has served on 10 National Academies committees and was a Presidential appointee and regulator of the Board of Directors of the Tennessee Valley Authority for two terms (2010-2017). In 2020 she was elected to both the National Academy of Sciences and the National Academy of Engineering, and in 2022 to the American Academy of Arts and Sciences. https://cassyni-user-files-prod.s3.amazonaws.com/QWCiWLqNcgC8cnDGSGnuNv https://cassyni.com/slides/outline/6sERuzD3FaG85cDiGeDUMT https://cassyni.com/events/6sERuzD3FaG85cDiGeDUMT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Bgq26amJqqtwPVNfy6RyCr https://cassyni.com/events/6sERuzD3FaG85cDiGeDUMT?videoPreview=1 Workshop Feedback (Plenary)nohttps://cassyni.com/events/6sERuzD3FaG85cDiGeDUMT?videoPreview=12026-02-25T13:50:00+00:001657.2Researcher to ReaderThis seminar presented feedback from five workshops addressing key challenges in scholarly communications. Workshop A explored responsible AI use in scholarly writing, noting a consensus for transparent disclosure and emphasizing the need for early-stage support and global standards. Workshop B focused on enhancing peer review quality and speed through incentives, developing two primary models: a non-monetary review reciprocity system for authors and a monetary pan-publisher reviewer marketplace. Workshop C tackled complexities in book metadata supply chains, highlighting a disconnect between publisher-generated data and downstream utility, along with challenges in standard harmonization and versioning. Proposed solutions included mapping existing standards, improving handling of ambiguous data, fostering feedback loops between libraries and publishers, and investigating AI-powered tools for metadata translation and content discovery. Workshop D examined better community engagement, differentiating genuine engagement from mere information dissemination (e.g., surveys). Key findings underscored the importance of active listening, building trust, and establishing transparent feedback loops to ensure communities feel heard and valued. Finally, Workshop E addressed responses to global emergencies, categorizing situations into immediate shock responses and longer-term restoration efforts. Access to trusted information was identified as a critical need, with solutions involving federated content, interoperability, and AI-driven translation and summarization. Future work includes forming a task group to assess user needs, map stakeholders, build coalitions, and develop a proposal for an industry-wide consultation on integrated emergency response strategies.https://cassyni-user-files-prod.s3.amazonaws.com/Bgq26amJqqtwPVNfy6RyCr https://cassyni.com/events/GkCWqf9Y2jLSw8DjnCyqVP/seminar/qa https://cassyni.com/slides/outline/GkCWqf9Y2jLSw8DjnCyqVP https://cassyni.com/events/GkCWqf9Y2jLSw8DjnCyqVP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FrRNziouiEcbbeR9Weksg https://cassyni.com/events/GkCWqf9Y2jLSw8DjnCyqVP?videoPreview=1 What I did; what I would do differentlynohttps://cassyni.com/events/GkCWqf9Y2jLSw8DjnCyqVP?videoPreview=12026-03-24T03:00:00+00:004026.0The Auckland Bioengineering InstituteThe pathway along which aspiring academics will need to navigate in the near future will probably be quite different from that traversed by previous generations. Yet the values that draw us forward remain unchanged: a love of discovery, knowledge, insight, rigour, and invention; the pleasure of teaching and helping others to grow; the satisfaction of seeing our work create impact in our communities or industries. In this talk, I reflect on the pathway by which I have travelled to where I am today. Perhaps there are insights that I have gained that can be useful to others? What worked for me, and what proved less successful? I hope that such reflection may help us all to chart our own directions - realise our own contentment, 'choose our future regrets', and ultimately help us to find satisfaction and pleasure in what we do. https://cassyni-user-files-prod.s3.amazonaws.com/FrRNziouiEcbbeR9Weksg https://cassyni.com/slides/outline/BoiUNpgHe9oRY2WPmjGqmF https://cassyni.com/events/BoiUNpgHe9oRY2WPmjGqmF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GTJ48BxDM9NU5qKDH9poL2 https://cassyni.com/events/BoiUNpgHe9oRY2WPmjGqmF?videoPreview=1 Scientific Publishing in Ukraine: Conquering Adversity (Lightning Talk)nohttps://cassyni.com/events/BoiUNpgHe9oRY2WPmjGqmF?videoPreview=12026-02-25T11:00:00+00:00635.96Researcher to ReaderUkrainian science is producing some incredible advances - in drone technology and more. Publishing too is defying the odds with 97% of the top 2,000 journals in open access. Hear about this along with opportunities arising from January’s event with top Ukrainian policy makers and practitioners at the Oxford International Centre for Publishing and Journalism, Oxford Brookes University.https://cassyni-user-files-prod.s3.amazonaws.com/GTJ48BxDM9NU5qKDH9poL2 https://cassyni.com/slides/outline/Q9xCeYNJ1xa1aBSc2en1Y1 https://cassyni.com/events/Q9xCeYNJ1xa1aBSc2en1Y1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/K7b8kmyad1TSFyTGz6AtBQ https://cassyni.com/events/Q9xCeYNJ1xa1aBSc2en1Y1?videoPreview=1 Welcome Plenarynohttps://cassyni.com/events/Q9xCeYNJ1xa1aBSc2en1Y1?videoPreview=12026-04-20T08:00:00+00:002376.24Research Analytics SummitSummit welcome by Dr. Baron G. Wolf and opening talk.https://cassyni-user-files-prod.s3.amazonaws.com/K7b8kmyad1TSFyTGz6AtBQ https://cassyni.com/events/JipZ92FXBvUwBKCNRjnDYZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/B5WsdJqd1ScGwHX8LRFZX4 https://cassyni.com/events/JipZ92FXBvUwBKCNRjnDYZ?videoPreview=1 D3 – Demystifying SQL: Interpreting and Building Queries for Beginnersnohttps://cassyni.com/events/JipZ92FXBvUwBKCNRjnDYZ?videoPreview=12026-04-20T13:30:00+00:002836.68Research Analytics SummitEver wanted to know more about SQL (Standard Query Language)? SQL is the language behind data – driven decisions, but for many beginners and non – coders, it can feel intimidating. This session will demystify SQL for beginners by building upon an Excel – based mental framework. We will break down the basics of SQL in a clear, approachable way. You’ll learn how to interpret existing queries, understand their structure, and build your own from scratch—without needing a programming background. This presentation will provide use cases and resources for applying SQL in day – to – day research administration tasks using publicly available datasets. By the end, participants should comfortable reading and interpreting basic SQL statements.https://cassyni-user-files-prod.s3.amazonaws.com/B5WsdJqd1ScGwHX8LRFZX4 https://cassyni.com/slides/outline/Vb5rA4V4qzfQhb2Q3H1uVP https://cassyni.com/events/Vb5rA4V4qzfQhb2Q3H1uVP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FpFjw9p585rvPYGw3FwsY2 https://cassyni.com/events/Vb5rA4V4qzfQhb2Q3H1uVP?videoPreview=1 I5- A discussion of the challenges and opportunities facing research offices and research services teams through results of an international surveynohttps://cassyni.com/events/Vb5rA4V4qzfQhb2Q3H1uVP?videoPreview=12026-04-21T13:30:00+00:002661.52Research Analytics SummitResearch Professional News conducted two international surveys in 2025 to examine the challenges and opportunities facing research offices and research services teams, and to consider what the future might hold. The first survey was targeted at people working in research offices and academic research services, while the second was aimed at researchers. Both surveys received more than 1,100 responses, with an overall total of more than 2,500 people taking part. Results from the survey are summarized in a report that highlights top priorities, change drivers, researcher expectations, the effects of the US government's policy changes, and views on societal impact and AI. Results are also compared to a prior iteration of the survey from 2023. Some key findings: Around a third of research office staff are using AI to find funding opportunities and edit grant applications. However, AI use is also singled out as the biggest threat to research integrity. The effects of the US government’s approach to research policy are being felt around the world, with respondents in many regions reporting lost research funding and fewer US collaborations. The survey results will be presented and a discussion with the audience will follow. The goal of this session is to inform the audience about trends in the research management community, get their input, and help them incorporate the findings into their strategy and future work.https://cassyni-user-files-prod.s3.amazonaws.com/FpFjw9p585rvPYGw3FwsY2 https://cassyni.com/events/EmdimZ5KgG3nPejh2dCAwf/seminar/qa https://cassyni.com/slides/outline/EmdimZ5KgG3nPejh2dCAwf https://cassyni.com/events/EmdimZ5KgG3nPejh2dCAwf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7WEtQHixt3HRMLmUL5QJpW https://cassyni.com/events/EmdimZ5KgG3nPejh2dCAwf?videoPreview=1 Liver Stiffness, MASLD and Liver Tumorigenesisnohttps://cassyni.com/events/EmdimZ5KgG3nPejh2dCAwf?videoPreview=12026-03-23T11:48:06+00:001106.04Advanced OncologyThis talk starts with the corresponding authors' presentation of the findings by Ma, et al, on the relationship between liver stiffness and metabolic dysfunction-associated liver disease (MASLD), then continue to discuss how mechanic stress may contribute to liver tumorigenesis.https://cassyni-user-files-prod.s3.amazonaws.com/7WEtQHixt3HRMLmUL5QJpW https://cassyni.com/events/QedRorXhrn3qPeS7pktyiD/seminar/qa https://cassyni.com/slides/outline/QedRorXhrn3qPeS7pktyiD https://cassyni.com/events/QedRorXhrn3qPeS7pktyiD/abstract https://cassyni.com/events/QedRorXhrn3qPeS7pktyiD?videoPreview=1 MIB Information Session: The Two Lane Approach to Assessmentnohttps://cassyni.com/events/QedRorXhrn3qPeS7pktyiD?videoPreview=12026-04-20T22:00:00+00:003275.68Management and International BusinessThis practical, staff-focused workshop is designed for teaching colleagues in the Master of International Business (MIB) and related areas of Management and Innovation and Entrepreneurship, responding to questions about how the University of Auckland’s Two-Lane Approach to assessment applies in practice. Grounded in current Assessment Policy and Procedures, and good assessment practice, the session will clarify what Lane 1 (controlled) and Lane 2 (uncontrolled) assessment mean in an AI-enabled environment, and how the two lanes work together across a whole-of-programme design. The session aims to put minds at ease by offering clear guidance, shared language, and concrete design strategies while creating space for questions and discussion about local implementation timelines and expectations within MIB and cognate programmes. https://cassyni.com/slides/outline/Y4MVW7EaSeMftDxandki8D https://cassyni.com/events/Y4MVW7EaSeMftDxandki8D/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HX88jYiqUWXy2LgPpEXYnr https://cassyni.com/events/Y4MVW7EaSeMftDxandki8D?videoPreview=1 Uncovering Cryptic Genes: Functional Dissection of HSV-1 as a Neuron-Specific Virulence Factornohttps://cassyni.com/events/Y4MVW7EaSeMftDxandki8D?videoPreview=12025-09-16T10:00:00+00:003319.0Journal of VirologyFor decades, herpes simplex virus 1 has been a model for studying viral pathogenesis. But even in this well-charted genome, there are still uncharted territories. In this Journal of Virology® Seminar Series webinar, Drs. Akihisa Kato and Yasushi Kawaguchi share the story of how they uncovered a cryptic gene—UL31.6—hidden in plain sight and revealed its unexpected role in neurovirulence. Through a combination of ribosome profiling, proteomics, and classical virological methods, they have shown how this hidden gene plays a critical role in viral spread and neurovirulence, offering fresh insights into tissue-specific pathogenicity and challenging long-held assumptions about HSV-1 biology. https://cassyni-user-files-prod.s3.amazonaws.com/HX88jYiqUWXy2LgPpEXYnr https://cassyni.com/events/SdDqzb7occGbVMiMBikv8m/seminar/qa https://cassyni.com/slides/outline/SdDqzb7occGbVMiMBikv8m https://cassyni.com/events/SdDqzb7occGbVMiMBikv8m/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WpGunBEob2KwM44DeqLnHL https://cassyni.com/events/SdDqzb7occGbVMiMBikv8m?videoPreview=1 From Cells to Cities: Towards Geometric Intelligence across Physical Scalesnohttps://cassyni.com/events/SdDqzb7occGbVMiMBikv8m?videoPreview=12026-04-14T19:00:00+00:002684.12School of Data ScienceI will present our recent work on how machines can understand, generate, and interact with 3D geometry across physical scales. We first show that geometric priors for shape understanding transfer across vastly different domains, such as molecular structures, human bodies, and 3D scenes. We then model how humans interact with environments without any captured 3D interaction data, and create interactable 3D objects with part-level articulation. Finally, we scale up to building digital twins for large-scale physical spaces, generating large-scale 3D environments from incomplete real-world observations. These efforts are steps toward universal 3D foundation models for analyzing, generating, and interacting with the physical world.https://cassyni-user-files-prod.s3.amazonaws.com/WpGunBEob2KwM44DeqLnHL https://cassyni.com/slides/outline/2RTEj6R67B8hKfxWFwTciR https://cassyni.com/events/2RTEj6R67B8hKfxWFwTciR/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LEQVk4xbxNyHVNP4qggPQA https://cassyni.com/events/2RTEj6R67B8hKfxWFwTciR?videoPreview=1 The Great Exclusion: How the Silver Tsunami Threatens to Bypass Black Entrepreneurs and Widen the Racial Wealth Gapnohttps://cassyni.com/events/2RTEj6R67B8hKfxWFwTciR?videoPreview=12025-11-19T19:00:00+00:00924.6Center for Black Entrepreneurship, Spelman CollegeThe "Silver Tsunami," a projected $70 trillion intergenerational wealth transfer from retiring baby boomers, presents a significant economic opportunity. However, concerns exist that this transfer may bypass Black entrepreneurs, thereby exacerbating the racial wealth gap. This research quantifies the scope of this opportunity for business owners and identifies barriers to participation for Black founders, focusing on entrepreneurship through acquisition (ETA). The study utilized 2022 HRS data from the University of Michigan, analyzing over 20,000 respondents, specifically filtering for employer firms with positive operating income. Company valuations were estimated by applying 2x and 3x multiples to operating income, and it was assumed that 50% of these businesses would be sale-eligible. The analysis reveals that over 40% of employer businesses are owned by individuals aged 55 and older, yet Black entrepreneurs own only 2-3% of employer firms, significantly below their 14% population parity. Black families collectively hold just 1.4% of the nation's $30.8 trillion in business equity. Without intervention, this ongoing wealth transfer risks widening existing disparities. The quantified opportunity for Black ownership in sale-eligible businesses is estimated at $29.9 billion (base estimate) to $44.8 billion (upper-bound estimate). It is recommended that educational initiatives promote ETA as a viable pathway to entrepreneurship, with organizations like New Majority Capital supporting Black, Native American, and Latino/Latina founders in securing capital and sourcing deals to facilitate business acquisitions, thereby fostering wealth creation and economic opportunities.https://cassyni-user-files-prod.s3.amazonaws.com/LEQVk4xbxNyHVNP4qggPQA https://cassyni.com/slides/outline/HjabGuzF7jE9TNpa2Y1efX https://cassyni.com/events/HjabGuzF7jE9TNpa2Y1efX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Pk91No77JzkNj5P8zk51Dx https://cassyni.com/events/HjabGuzF7jE9TNpa2Y1efX?videoPreview=1 ML-based general-purpose closure model for large-eddy simulationnohttps://cassyni.com/events/HjabGuzF7jE9TNpa2Y1efX?videoPreview=12026-05-21T18:00:00+00:004199.08AI Institute in Dynamic SystemsThe predictive capabilities of computational fluid dynamics, which are critical to aerodynamic design, depend on the development of accurate closure models. However, no practical model has emerged that is universally applicable across the wide range of flow regimes relevant to industry. We introduce a closure model for large-eddy simulation, referred to as the Building-block Flow Model (BFM). This model is founded on the premise that a finite set of simple flows encapsulates the essential physics needed to predict more complex scenarios. The BFM is implemented using artificial neural networks and introduces five key advancements within the large-eddy simulation framework: (1) it is designed to predict multiple flow regimes, including laminar flow; wall turbulence under zero, favorable, and adverse mean-pressure gradients; separation; wall heat transfer; and wall roughness effects; (2) it leverages information-theoretic dimensional analysis to select the most relevant nondimensional input and output variables; (3) it ensures consistency with numerical schemes and gridding strategies by accounting for numerical errors; (4) it is directly applicable to arbitrary complex geometries; and (5) it provides explainability and confidence in the predictions. The BFM is used to predict key quantities of interest across a wide range of cases, including turbulent pipe flows, rough turbine blades, speed bumps, aircraft in landing configurations, and hypersonic flows in entry, descent, and landing vehicles.https://cassyni-user-files-prod.s3.amazonaws.com/Pk91No77JzkNj5P8zk51Dx https://cassyni.com/slides/outline/2v8TtQaVwzcX9SXs1tBv7o https://cassyni.com/events/2v8TtQaVwzcX9SXs1tBv7o/abstract https://cassyni-user-files-prod.s3.amazonaws.com/V73fqBjtCPwb9CD7iGgncv https://cassyni.com/events/2v8TtQaVwzcX9SXs1tBv7o?videoPreview=1 Beyond Antigen Presentation: The Intrinsic Role of Tumor-Cell CD1d Expression in Cancernohttps://cassyni.com/events/2v8TtQaVwzcX9SXs1tBv7o?videoPreview=12026-07-13T14:00:00+00:003033.68Immunity, Inflammation and Disease JournalCD1d is traditionally recognized as an MHC class I-like antigen-presenting molecule involved in lipid antigen presentation to Natural Killer T (NKT) cells. However, emerging paradigms reveal that its expression on malignant epithelial cells directly influences tumor-intrinsic functions, independent of classical immune surveillance. In this webinar, we will explore the evolving role of tumor-cell CD1d in aggressive cancer. The presentation will discuss how aberrant CD1d expression influences key hallmarks of tumor progression, including proliferation, survival, migration, and epithelial-mesenchymal transition (EMT). We will examine mechanistic insights into how tumor-associated CD1d modulates cell plasticity, stemness-associated pathways, and interactions with the tumor microenvironment beyond its canonical role in antigen presentation. Emphasis will be placed on emerging in vitro and translational findings linking CD1d signaling to metastatic behavior and therapeutic resistance. By mapping these precise in vitro processing dynamics, this webinar bridges the gap between basic tumor immunology and translational drug discovery. Ultimately, we will discuss how uncovering these distinct, non-canonical CD1d pathways on cancer cells shifts our therapeutic focus away from broad immune stimulation and toward targeted interventions. Disrupting this intrinsic tumor-cell axis offers a novel, highly sophisticated therapeutic window to halt metastatic progression and overcome immune evasion in aggressive malignancies.https://cassyni-user-files-prod.s3.amazonaws.com/V73fqBjtCPwb9CD7iGgncv https://cassyni.com/slides/outline/AKrXafHNXrvMe24Kym3eXo https://cassyni.com/events/AKrXafHNXrvMe24Kym3eXo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8ztDTVnG6e9CHxFmJU6kGN https://cassyni.com/events/AKrXafHNXrvMe24Kym3eXo?videoPreview=1 Science Advocacy in Action: Proteolytic Activation of Influenza A Virusnohttps://cassyni.com/events/AKrXafHNXrvMe24Kym3eXo?videoPreview=12026-03-04T06:00:00+00:00574.84Journal of VirologyUnderstanding how influenza A virus becomes infectious is critical to reducing its global impact. Research on the proteolytic activation of hemagglutinin shows how specific airway cell types drive viral infectivity and replication, shaping how infection begins and spreads. These insights inform the development of host-targeted, broad-spectrum antivirals that may remain effective as influenza viruses evolve. By revealing fundamental mechanisms of respiratory virus entry, this work strengthens preparedness for future influenza outbreaks and emerging viral threats. https://cassyni-user-files-prod.s3.amazonaws.com/8ztDTVnG6e9CHxFmJU6kGN https://cassyni.com/slides/outline/PfPTwkGRnao3fi4KRZ8QqB https://cassyni.com/events/PfPTwkGRnao3fi4KRZ8QqB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BxmqjbfQjPTq16nfGo5dpA https://cassyni.com/events/PfPTwkGRnao3fi4KRZ8QqB?videoPreview=1 From Nucleus to Cytoplasm: Primary Envelopment in Kaposi’s Sarcoma-Associated Herpesvirusnohttps://cassyni.com/events/PfPTwkGRnao3fi4KRZ8QqB?videoPreview=12026-05-04T11:00:00+00:003723.08Journal of VirologyIn this Journal of Virology® Seminar Series webinar, Alexa Wilson, PhD (Dalhousie University) showcases high‑resolution transmission electron microscopy, confocal microscopy, and spinning disc microscopy to examine how Kaposi’s sarcoma–associated herpesvirus (KSHV) engages the nucleoplasmic reticulum (NR) during lytic replication. Wilson also presents new advances in live‑cell imaging that enable tracking of individually labeled viral genomes as they enter, move through, and exit the NR—revealing a previously underappreciated pathway for primary envelopment and nuclear egress. Integrated throughout the session, she highlights the dynamic morphology of the NR at ~50,000× magnification, demonstrates cutting‑edge techniques for labeling and tracking herpesvirus capsids, and explains how this updated model of NR‑mediated egress reframes the search for future antiviral strategies targeting early replication steps. https://cassyni-user-files-prod.s3.amazonaws.com/BxmqjbfQjPTq16nfGo5dpA https://cassyni.com/slides/outline/WaTvbKKmvzYqAX3tnzhLys https://cassyni.com/events/WaTvbKKmvzYqAX3tnzhLys/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6T5n1LCq1EL24gnZCcaPu8 https://cassyni.com/events/WaTvbKKmvzYqAX3tnzhLys?videoPreview=1 Thrust generation mechanics and energetics of self-propelled oscillating foilsnohttps://cassyni.com/events/WaTvbKKmvzYqAX3tnzhLys?videoPreview=12026-06-26T10:00:00+00:002263.12Department of AeronauticsA wide array of natural and artificial swimmers and flyers adhere to a seemingly universal relationship between their propulsive kinematics and forward speed. Most commonly expressed through the Strouhal–Reynolds number (St–Re) scaling, this relationship links a locomotor's transverse oscillation frequency and amplitude to its mean forward speed. It has long fascinated researchers and carries broad significance, as it justifies the study of undulatory biolocomotion through relatively simple model systems self-propelled by foil-like oscillating kinematics. In this talk, we examine the energetic and dynamical implications of universality in the St–Re scaling relation. We show that self-propelled systems as distinct as those driven by recoil-based thrust and by leading-edge suction can converge to a common scaling regime under intense flapping, a convergence that arises principally from asymptotic similarities in thrust generation at high reduced frequencies. Crucially, we demonstrate that this apparent scaling consistency does not translate into uniform energetic efficiency: significant differences in locomotory performance emerge across systems governed by a similar St–Re relation. https://cassyni-user-files-prod.s3.amazonaws.com/6T5n1LCq1EL24gnZCcaPu8 https://cassyni.com/slides/outline/X57XdzyJNT6tAHanPRz9FB https://cassyni.com/events/X57XdzyJNT6tAHanPRz9FB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4ECCWrUGNTFaMrzzHadLxE https://cassyni.com/events/X57XdzyJNT6tAHanPRz9FB?videoPreview=1 Thermal limits of plant reproduction: when pollen sets the boundary of lifenohttps://cassyni.com/events/X57XdzyJNT6tAHanPRz9FB?videoPreview=12026-06-04T07:00:00+00:001803.68Climate warming is pushing biological systems towards their thermal limits, yet most assessments of plant heat tolerance focus on vegetative tissues. Reproduction, particularly the male gametophyte, may represent a more vulnerable and ultimately limiting stage. Here, I synthesise comparative and experimental evidence demonstrating that pollen thermal sensitivity constrains plant performance across ecological and evolutionary scales. First, a global synthesis across 191 species shows that pollen temperature limits (Tmin, Topt, Tmax) vary widely but are consistently lower than those of vegetative tissues. Pollen heat tolerance is only weakly associated with leaf tolerance and exhibits phylogenetic conservatism and climatic structuring, indicating evolutionary constraint. Second, experimental chronic heat stress in wild species reveals strong reductions in male gametophyte performance and seed production, even when seed mass and germination capacity are largely maintained. Third, a newly compiled database covering 274 species highlights large interspecific variation in pollen longevity, suggesting that functional lifespan further narrows the effective fertilisation window under hot and desiccating conditions. Together, these findings indicate that species persistence under extreme heat may be constrained less by vegetative survival than by the thermal vulnerability and temporal limitation of pollen function. Incorporating reproductive thermal limits is therefore essential for predicting plant responses to climate change.https://cassyni-user-files-prod.s3.amazonaws.com/4ECCWrUGNTFaMrzzHadLxE https://cassyni.com/slides/outline/6NhKKpd4RZQvzqJ3sDQ3ZX https://cassyni.com/events/6NhKKpd4RZQvzqJ3sDQ3ZX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/H3TQU6UnXqr94G3U9FyZ4J https://cassyni.com/events/6NhKKpd4RZQvzqJ3sDQ3ZX?videoPreview=1 High-beta runaway transitions in a fluid model of electromagnetic ion-temperature-gradient turbulencenohttps://cassyni.com/events/6NhKKpd4RZQvzqJ3sDQ3ZX?videoPreview=12026-06-25T15:00:00+00:003348.56Journal of Plasma PhysicsGyrokinetic simulations of tokamak turbulence indicate that fluctuation levels increase abruptly and dramatically when the plasma beta exceeds a certain critical value. This increase in fluctuation levels coincides with a transition from a state dominated by zonal flow to one in which turbulent eddies form radially-elongated `streamers'. Here we derive from gyrokinetics a minimal fluid model for electromagnetic ion-temperature-gradient (ITG) turbulence that captures the key features of this transition. Due to the relative simplicity of the model, we are able to conduct a detailed numerical study of the interplay between the turbulence and the zonal flow across a broad range of values of the plasma beta and the ITG. We find that the transition occurs when the Reynolds stress, which tends to strengthen zonal flows, is overwhelmed by the Maxwell and diamagnetic stresses, which tend to weaken them. Power-law scalings of the stress ratios with plasma beta and ITG are obtained, indicating a possible means by which the location of the transition could be predicted with minimal computational cost.https://cassyni-user-files-prod.s3.amazonaws.com/H3TQU6UnXqr94G3U9FyZ4J https://cassyni.com/slides/outline/8qwLZErgcrBRMmmcQuJgHT https://cassyni.com/events/8qwLZErgcrBRMmmcQuJgHT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QxXb8BwuTPuBjie9yCWaUe https://cassyni.com/events/8qwLZErgcrBRMmmcQuJgHT?videoPreview=1 Advancing a Shared Language: The 2026 Revision of the Educational Methodology Vocabularynohttps://cassyni.com/events/8qwLZErgcrBRMmmcQuJgHT?videoPreview=12026-07-14T17:00:00+00:003619.16AAMCAll health professions programs need to document how they teach and assess their curricular content. Educational methods are the various instructional and assessment approaches that educators use to facilitate learning, enhance engagement, and assess progress. Consistent documentation of educational methods, using standardized terms and definitions, produces data about curricula in health professions education that facilitate national dialogue and dissemination of scholarship. Join the webinar on July 14, 1 PM ET, to learn how the revised educational methods list features clearer definitions and a flexible matrix model to support varying reporting needs. Leaders from the Educational Methods Working Group, a collaboration between the AAMC’s MedBiquitous and Curricular Resources, will offer an overview of the revised terms, including reflections on how the list was updated to bring greater clarity and consistency to defining and using educational data, as well as insight into the new matrix model and a preview of implementation resources. Through a shared language, the updated terms and the matrix model aim to strengthen curricular mapping, support accreditation needs, as well as improve data sharing and comparison across health professions education (HPE).https://cassyni-user-files-prod.s3.amazonaws.com/QxXb8BwuTPuBjie9yCWaUe https://cassyni.com/events/SDGrz9p2ysubjahrjh3qP/seminar/qa https://cassyni.com/slides/outline/SDGrz9p2ysubjahrjh3qP https://cassyni.com/events/SDGrz9p2ysubjahrjh3qP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QVeGxPyFrQf7T6J5HGWoYi https://cassyni.com/events/SDGrz9p2ysubjahrjh3qP?videoPreview=1 RAMP 2026-27 Community Call #2nohttps://cassyni.com/events/SDGrz9p2ysubjahrjh3qP?videoPreview=12026-07-10T16:00:00+00:001729.68Research Evaluation and Analytics Capacity HubApplications for the Research Analytics Mentorship Program (RAMP) open on July 8th! We are looking for both mentors and mentees looking to join a community of research analytics professionals dedicated to learning, collaboration, and professional growth. RAMP brings together research analytics professionals from across the country and international locations to share knowledge, expand their networks, and learn from one another through mentorship and peer collaboration. Whether you're interested in growing your skills as a mentee or sharing your experience as a mentor, we invite you to join our next cohort. Join our community call to learn more about the program, ask questions, and help to prepare your application. Both community calls will cover the same content for those interested in the program. https://cassyni-user-files-prod.s3.amazonaws.com/QVeGxPyFrQf7T6J5HGWoYi https://cassyni.com/slides/outline/FGRSPPJH8XEU87LS1jnWbF https://cassyni.com/events/FGRSPPJH8XEU87LS1jnWbF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5HKfhDK6uUnyptwU3A5wNN https://cassyni.com/events/FGRSPPJH8XEU87LS1jnWbF?videoPreview=1 C-H Alkylation of Heteroarenes Enabled by Earth-Abundant Iron and Nickel-Based Metal Catalystsnohttps://cassyni.com/events/FGRSPPJH8XEU87LS1jnWbF?videoPreview=12026-08-07T08:00:00+00:003889.72Thieme India ChemTalksDeveloping transition metal catalysts based on Earth-abundant metals is important to attain sustainable and environmentally benign chemical transformation. In this direction, transition metal catalysts based on iron and nickel have been given considerable attention, particularly for the C−H bond functionalization of biorelevant heteroarenes. To this end, our research activities have been focused on the design and development of suitably ligated nickel catalysts for selective CH alkylation of indoles, azoles and pyridones using unactivated alkyl halides. In this presentation, Ni-catalyzed regioselective CH bond alkylation and alkenylation of indoles, azoles and pyridones will be discussed. In addition, the focus will be paid to the mechanistic aspects of these reactions. Moreover, the use of iron complexes in the functionalization of indole derivatives will be deliberated. Overall, a comprehensive catalyst development, catalytic scope, and reaction mechanism of the Fe- and Ni-catalyzed functionalization of indoles, azoles and pyridones will be discussed.https://cassyni-user-files-prod.s3.amazonaws.com/5HKfhDK6uUnyptwU3A5wNN https://cassyni.com/events/9qHnssBWJV9PjF6CQpnibo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VNNnDhrsw48w6TXcKjTy5g https://cassyni.com/slides/outline/NByUyf7h84jc6jazGzhdFK https://cassyni.com/events/NByUyf7h84jc6jazGzhdFK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HB1UkpZSkwV3JRn9VC4mB4 https://cassyni.com/events/NByUyf7h84jc6jazGzhdFK?videoPreview=1 Geochemical Fingerprints of Human-Environment Dynamicsnohttps://cassyni.com/events/NByUyf7h84jc6jazGzhdFK?videoPreview=12026-08-21T01:30:00+00:002815.92Institute for Applied EcologyThis seminar will explore the application of an interdisciplinary framework to identify when people first arrived on remote Tropical West Pacific Islands. Lake sediments are excellent archives of environmental change and can be used to examine how a given site responded to changes in local and regional climate systems. Similarly, these records can be used to reconstruct how early human populations adapted to remote Tropical West Pacific Island environments. This has significant implications for archaeological science, particularly in regions where archaeological assemblages are sparse, owing to poor preservation and changing coastlines. https://cassyni-user-files-prod.s3.amazonaws.com/HB1UkpZSkwV3JRn9VC4mB4 https://cassyni.com/events/T8TXSVawWeGuZ9sfn5kzf7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9AHQm4kdVSu5kYixJyTUsG https://cassyni.com/events/9MRd2oxo98XeBkPEe49tKo/seminar/qa https://cassyni.com/slides/outline/9MRd2oxo98XeBkPEe49tKo https://cassyni.com/events/9MRd2oxo98XeBkPEe49tKo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3FJFe4NnhMkb3jBNP7RR5x https://cassyni.com/events/9MRd2oxo98XeBkPEe49tKo?videoPreview=1 Scientific Knowledge Processing​nohttps://cassyni.com/events/9MRd2oxo98XeBkPEe49tKo?videoPreview=12023-08-08T18:30:00+00:003547.6SCIWRITERIris.ai is one of the world’s leading start-ups in the research and development of AI technologies for science. Founded in 2015, the start-up offers an award-winning AI engine for scientific text understanding without compromising factual correctness. Iris.ai Researcher Workspace, a suite of AI-assisted research tools, is designed to help R&D professionals accelerate their entire scientific knowledge workflows: from exploring the right content (live & local datasets), smart filtering, and summarizing results to extracting data from papers or chatting with your datasets. Applied to literature reviews, exploratory searches, competitive intelligence, or any other task involving thousands of documents like papers or patents, researchers no longer waste time on tasks the Iris.ai tools can do for them. As the volume of scientific knowledge continues to surge at a staggering pace, organizing this information becomes as crucial as generating new insights. This significant task permeates all aspects of the scientific research process, which we encapsulate in the three "R's": _Research_ — to effectively discover relevant information, _Review_ — to critically evaluate existing knowledge, and _Recruitment_ — identifying the right individuals for research endeavors. **Prophy** addresses the challenges of streamlining knowledge management by enriching publication data with a semantic dimension. This additional layer enables a level of automation in the scientific process that was hitherto unattainable. In this talk, I will introduce two innovative Prophy solutions. The **Reviewer Finder**, designed for funding agencies and publishers, simplifies the process of identifying qualified peer reviewers for any documents. Meanwhile, our innovative **semantic search engine** provides individual researchers with a tool that significantly enhances their research capabilities. To promote more efficient research processes, we are pleased to offer the audience complimentary trial access to these powerful tools. Academic output continues to grow and it is increasingly difficult to find the relevant papers and authors for your project. Whether this is for your academic research to stay up to date with the latest insights or to find key opinion leaders, or as a funding agency or publisher to find relevant reviewers for the manuscripts you received, it is difficult to quickly navigate the field. Plus, there is a huge bias in Northwestern academic output, so you hardly find the experts you are looking for in the Global South. With **Global Campus** we are fixing this. Using the **open source information** from OpenAlex ensures one of the worlds largest pools of academic output, including output in the Global South. And with our own state-of-the-art **semantic search** we help you navigate quickly through the millions of publications out there. And last but not least, by using **active learning** algorithms, we make it even faster and easier to quickly find those set of papers that you were looking for. We don’t believe in throwing away valuable information, so instead of adding keywords and concepts to all the papers, we are using our semantic search algorithms directly in the titles and abstracts of the publications. This way, we can find relevant people and papers that use different concepts and words when describing the same phenomena. Global Campus is easy to use, you just describe your project, or copy/paste your abstract in the search bar and you can start searching! Global Campus: - Open and transparant about the results you can find because we use the open data from OpenAlex - Better results because we really compare your input text with title and abstracts of publications without reducing it to concepts or keywords - Faster navigating through our 'active learning algorithms' and smart filtering https://cassyni-user-files-prod.s3.amazonaws.com/3FJFe4NnhMkb3jBNP7RR5x https://cassyni.com/slides/outline/SADyh3sZwSNNVGmXCESStM https://cassyni.com/events/SADyh3sZwSNNVGmXCESStM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/R3vdqEysGYmJ8AGENFrbQz https://cassyni.com/events/SADyh3sZwSNNVGmXCESStM?videoPreview=1 Plant-soil-ecosystem-landscape interactions in urban environmentsnohttps://cassyni.com/events/SADyh3sZwSNNVGmXCESStM?videoPreview=12024-08-13T12:00:00+00:001462.24The New Phytologist FoundationStudies on the ecology of urban systems tend to focus on the big cities, yet many urban areas comprise smaller towns where urbanness may influence ecosystem functions differently to larger cities. Moreover, ecosystem processes operate across very wide spatial scales, including the potential to be influenced by the landscape context, and this makes it imperative to identify mechanisms driving ecosystem processes in urban areas. These gaps make it hard to e.g. restore systems, not least because our understanding of mechanisms below ground in soil are also poorly resolved. Here I present findings from current projects seeking to understand how urbanness affects ecosystem processes, including those in soil, across multiple scales from within an individual greenspace to the UK, and where active restoration programmes have been implemented. https://cassyni-user-files-prod.s3.amazonaws.com/R3vdqEysGYmJ8AGENFrbQz https://cassyni.com/slides/outline/LEPUub5VsDsNihjbBqFQqs https://cassyni.com/events/LEPUub5VsDsNihjbBqFQqs/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WGepgECDMHuM7VdayjJKt2 https://cassyni.com/events/LEPUub5VsDsNihjbBqFQqs?videoPreview=1 1.4 The Social Context: ScholComm is Peoplenohttps://cassyni.com/events/LEPUub5VsDsNihjbBqFQqs?videoPreview=12024-11-22T17:00:00+00:003498.96Medical Library Association’s Scholarly Communications CaucusExplore the impact of social forces on scholarly communication and the role of librarians.https://cassyni-user-files-prod.s3.amazonaws.com/WGepgECDMHuM7VdayjJKt2 https://cassyni.com/events/YZ2ifRPzHTqVhzXwYaV1Xb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/SGFptxDPkKeyKwYRuSsV2N https://cassyni.com/slides/outline/2vSK9LFFNxoWkhCHA8Wn4d https://cassyni.com/events/2vSK9LFFNxoWkhCHA8Wn4d/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3E7J9dCRizsxiKuEv27542 https://cassyni.com/events/2vSK9LFFNxoWkhCHA8Wn4d?videoPreview=1 Escape--Overturenohttps://cassyni.com/events/2vSK9LFFNxoWkhCHA8Wn4d?videoPreview=12020-09-19T12:00:00+00:0092.72Hong Kong Baptist UniversityJun Pan reads her poem, 'Escape--Overture' from "Mingled Voices 3: International Proverse Poetry Prize Anthology 2018", p 106 .https://cassyni-user-files-prod.s3.amazonaws.com/3E7J9dCRizsxiKuEv27542 https://cassyni.com/events/3R5vC1tmpRMZkTjAkZoaKw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7dJ8h3mvd5zeQwnfPJ3bjt https://cassyni.com/events/3R5vC1tmpRMZkTjAkZoaKw?videoPreview=1 Christian Perspective on Virtuesnohttps://cassyni.com/events/3R5vC1tmpRMZkTjAkZoaKw?videoPreview=12021-09-29T12:00:00+00:00309.44Hong Kong Baptist UniversityWhat is virtue? Why does virtue matter? What does it mean to us?https://cassyni-user-files-prod.s3.amazonaws.com/7dJ8h3mvd5zeQwnfPJ3bjt https://cassyni.com/slides/outline/CoQQ51BkA7sqcDCJfhH9CZ https://cassyni.com/events/CoQQ51BkA7sqcDCJfhH9CZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7Kintrrx2GyDy9xJehPXxa https://cassyni.com/events/CoQQ51BkA7sqcDCJfhH9CZ?videoPreview=1 Yoonie Han plays Liszt Piano Concerto No. 1 with Collegium Musicum HKnohttps://cassyni.com/events/CoQQ51BkA7sqcDCJfhH9CZ?videoPreview=12021-11-12T12:00:00+00:001175.24Hong Kong Baptist UniversityKorean-American pianist Yoonie Han plays Liszt Piano Concerto No. 1 at the Hong Kong City Hall with the Collegium Musicum during Festive Korea, November 2021.https://cassyni-user-files-prod.s3.amazonaws.com/7Kintrrx2GyDy9xJehPXxa https://cassyni.com/slides/outline/WaKp2AkLvBvCRpz3QKPobb https://cassyni.com/events/WaKp2AkLvBvCRpz3QKPobb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PWEsKMmf5remsrRcpo14dC https://cassyni.com/events/WaKp2AkLvBvCRpz3QKPobb?videoPreview=1 Atheism in Jainismnohttps://cassyni.com/events/WaKp2AkLvBvCRpz3QKPobb?videoPreview=12021-09-15T12:00:00+00:00350.32Hong Kong Baptist UniversityWhat is Jainism? Do Jains worship gods or the liberated souls? Are these gods stay permanently as gods forever?https://cassyni-user-files-prod.s3.amazonaws.com/PWEsKMmf5remsrRcpo14dC https://cassyni.com/slides/outline/8qoDz6HFc3Ynd5hm2E18uB https://cassyni.com/events/8qoDz6HFc3Ynd5hm2E18uB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/1784a3s3CWHJXZgW7dk2v2 https://cassyni.com/events/8qoDz6HFc3Ynd5hm2E18uB?videoPreview=1 Teh Tarik with Walid Episode 104: Professor Kenneth Paul Tannohttps://cassyni.com/events/8qoDz6HFc3Ynd5hm2E18uB?videoPreview=12025-03-17T12:00:00+00:003574.56Hong Kong Baptist University“Teh Tarik with Walid: Singapore politics for beginners” is hosted by academic Dr Walid Jumblatt Bin Abdullah. He works on state-Islam relations, and political parties and elections, with particular focus on Singapore and Malaysia.https://cassyni-user-files-prod.s3.amazonaws.com/1784a3s3CWHJXZgW7dk2v2 https://cassyni.com/slides/outline/DnhcANUo32yzGy2JmfkU1T https://cassyni.com/events/DnhcANUo32yzGy2JmfkU1T/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5xxqaDcERJV42HAoYZurvz https://cassyni.com/events/DnhcANUo32yzGy2JmfkU1T?videoPreview=1 A Dialogue on the Ethics of ChatGPT in Schoolsnohttps://cassyni.com/events/DnhcANUo32yzGy2JmfkU1T?videoPreview=12023-04-25T12:00:00+00:005211.76Hong Kong Baptist UniversityMany schools, including HKBU are concerned about how the emergence of new Large Language Models like OpenAI's ChatGPT and Alibaba's Tongyi Qianwen will affect the educational setting. Concerns about increased academic dishonesty, the spread of misinformation, and disruption to pedagogical method need to be balanced against potential uses for facilitating research, improving learning comprehension and creative expression. This dialogue between three of BU's philosophers of technology will discuss these and other issues as well as concerns brought forward by the student body, faculty and administration about the ethical use of LLMs in the future of education.https://cassyni-user-files-prod.s3.amazonaws.com/5xxqaDcERJV42HAoYZurvz https://cassyni.com/slides/outline/ALANqax7xq7MFGik81NWUd https://cassyni.com/events/ALANqax7xq7MFGik81NWUd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2w5eXJ6feWtJug4bQjXmyG https://cassyni.com/events/ALANqax7xq7MFGik81NWUd?videoPreview=1 "The Railway and Ottoman Engagements with Anatolian Pasts"nohttps://cassyni.com/events/ALANqax7xq7MFGik81NWUd?videoPreview=12021-12-04T12:00:00+00:005473.8Hong Kong Baptist UniversityThis seminar explores multifaceted Ottoman engagements with the past and modernity through various forms of mobility and infrastructural development. One presentation analyzes civilian Ottoman travelogues and envoy reports from 1830-1860, demonstrating how London was perceived as a model for modern urban planning, emphasizing order, architectural harmony, and technological precision. Another study examines a 1910 architectural excursion by Kemalettin Bey and Nihat Bey to Cairo, Athens, and Alexandria, using Nihat Bey's personal archives. It highlights the influence of Mamluk architecture, particularly the Qaytbay complex, on Kemalettin Bey's subsequent national style designs, challenging existing architectural historiography. A third presentation investigates the Izmir-Aydın Railway’s opening to Ephesus in 1862, utilizing newspaper reportage and guidebooks. It reveals how Ottoman officials foregrounded Turko-Ottoman history during opening ceremonies, while the railway simultaneously accelerated tourism and archaeological interest in the ancient Greco-Roman past, facilitating excavations and the transport of antiquities. Collectively, these studies illuminate the complex interplay between technological advancements, cultural perceptions, national identity formation, and historical narratives in the late Ottoman Empire.https://cassyni-user-files-prod.s3.amazonaws.com/2w5eXJ6feWtJug4bQjXmyG https://cassyni.com/slides/outline/MC1L9BTNaVPva5WuVBvEiy https://cassyni.com/events/MC1L9BTNaVPva5WuVBvEiy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Dwa19RpmifQU61peN6Y7fc https://cassyni.com/events/MC1L9BTNaVPva5WuVBvEiy?videoPreview=1 "The West” and the Formation of Hong Kong Protestant Christian Leadersnohttps://cassyni.com/events/MC1L9BTNaVPva5WuVBvEiy?videoPreview=12024-10-19T12:00:00+00:001368.8Hong Kong Baptist UniversityThis study examines how encounters with Western culture and society shaped the worldview, faith, and identity of Hong Kong Protestant Christian leaders during the 1980s and 1990s, a transitional period marked by complex political and cultural shifts. Utilizing oral history interviews with key figures such as Tso Man King and Raymond Fung Wai Man, the analysis foregrounds their transnational experiences, which arose primarily from education and work rather than migration. These experiences expanded their intellectual, theological, and social horizons, enabling them to integrate Western theological concepts and social activism into the Hong Kong context while simultaneously influencing Western Christian thought. For instance, Tso’s engagement with African American communities and diplomatic actors in the United States exemplifies a strategic, intercultural ministry that informed his later ecumenical leadership in Hong Kong. Fung’s involvement with labor activism and the World Council of Churches reflects a creative synthesis of Western evangelical and ecumenical traditions adapted to local social realities. The study highlights a hybridity of identity among these leaders, where Chinese, Hong Kong, and Western influences coexist without dominance or erasure, fostering new theological insights and social practices. This hybridity also facilitated a reflective dialogue that projected Hong Kong and Chinese Christian perspectives back to Western contexts. The findings underscore the significance of non-migratory transnationalism in shaping religious leadership and identity formation in postcolonial Hong Kong, offering a nuanced understanding of cultural exchange and theological innovation in global Christianity.https://cassyni-user-files-prod.s3.amazonaws.com/Dwa19RpmifQU61peN6Y7fc https://cassyni.com/slides/outline/PfFMNbgzmnAQw1zU2spsSu https://cassyni.com/events/PfFMNbgzmnAQw1zU2spsSu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KBMznmCHy295NbEZJeombU https://cassyni.com/events/PfFMNbgzmnAQw1zU2spsSu?videoPreview=1 The Mysteries of Sanxingdui: Reflections on the Hong Kong Palace Museum Exhibitionnohttps://cassyni.com/events/PfFMNbgzmnAQw1zU2spsSu?videoPreview=12023-11-28T12:00:00+00:007353.6Hong Kong Baptist UniversityArchaeological excavations at Sanxingdui in Guanghan, Sichuan province, have revealed evidence of an ancient culture in the upper Yangtze River valley and in particular the Chengdu Plain. But what can we learn from Sanxingdui in terms of societal hierarchies and power dynamics, human values, and artistic and religious beliefs with a culture that left no evidence of communication or language? Reflecting on the intriguing exhibition of the new archaeological discoveries at Sanxingdui by the Hong Kong Palace Museum, The Hong Kong Jockey Club University of Chicago Academic Complex | The University of Chicago Francis and Rose Yuen Campus in Hong Kong has invited a panel of experts, including Dr. Wang Shengyu from the Hong Kong Palace Museum, Professor Li Kin Sum from Hong Kong Baptist University, and Professor Peng Peng from the Chinese University of Hong Kong. The experts will share their learnings from the Sanxingdui discoveries and discuss the cultural and historical significance of Sanxingdui in a program moderated by the University of Chicago Professor Edward Shaughnessy.https://cassyni-user-files-prod.s3.amazonaws.com/KBMznmCHy295NbEZJeombU https://cassyni.com/slides/outline/LCi83pAKhaHmuKguPDSuv5 https://cassyni.com/events/LCi83pAKhaHmuKguPDSuv5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4Zc4mYXMQQnrHfJrRVouot https://cassyni.com/events/LCi83pAKhaHmuKguPDSuv5?videoPreview=1 The Road to the Baroque—Masterpieces from the Capodimonte Museumnohttps://cassyni.com/events/LCi83pAKhaHmuKguPDSuv5?videoPreview=12022-09-24T12:00:00+00:006029.28Hong Kong Baptist UniversityIn this session, Dr Angelo Lo Conte, Assistant Professor of Academy of Visual Arts of the Hong Kong Baptist University, talked about the development of the Baroque style and its significance for the city of Naples, the second largest metropolis in Europe at the turn of the 17th century. Local artist Mr Kinglsey Ng explored the relationship of Baroque art and his installation, providing more insights into his artistic response to the works of the Baroque masters.https://cassyni-user-files-prod.s3.amazonaws.com/4Zc4mYXMQQnrHfJrRVouot https://cassyni.com/slides/outline/X4yR4rPsMeUFRbWvzkgbru https://cassyni.com/events/X4yR4rPsMeUFRbWvzkgbru/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7UshvDxMk1gAYxd4VmfktN https://cassyni.com/events/X4yR4rPsMeUFRbWvzkgbru?videoPreview=1 Robot Remix:Combining Music and Gestural Input to Drive a Calligraphy Robotnohttps://cassyni.com/events/X4yR4rPsMeUFRbWvzkgbru?videoPreview=12023-10-28T12:00:00+00:00158.64Hong Kong Baptist UniversityDr Peter Nelson is presenting this demonstration that connects a 6 degree of freedom robotic arm equipped with a Chinese ink brush to real-time software (TouchDesigner). This allows the user to move the robotic arm on two axes, while an external piece of music moves the third axis. The result is a robotic system that visualises a combination of mouse input and music as a painting. Both music and mouse input have been chosen for their operational simplicity, and could be replaced by signals from any range of sensors such as a webcam, heart-rate monitor, motion sensor, etc., and data sources, such as a spreadsheet of numerical values, a sound or video recording, and so on. Using TouchDesigner to mix and map these inputs and a Python OSC bridge to communicate with the robotic arm, this system demonstrates a flexible and accessible method for human-robot interaction and collaboration that can be creatively repurposed by the user for a broad range of applications.https://cassyni-user-files-prod.s3.amazonaws.com/7UshvDxMk1gAYxd4VmfktN https://cassyni.com/slides/outline/RdqmZLH6XcPB2jGhPqgosT https://cassyni.com/events/RdqmZLH6XcPB2jGhPqgosT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/b7Hxg1g7yE4sMka9zev5k https://cassyni.com/events/RdqmZLH6XcPB2jGhPqgosT?videoPreview=1 Divine Hiddenness and Dogmatic Authoritynohttps://cassyni.com/events/RdqmZLH6XcPB2jGhPqgosT?videoPreview=12024-12-10T12:00:00+00:003305.96Hong Kong Baptist UniversityFr. James Dominic Rooney returns to the podcast to discuss some of his recent work on divine hiddenness and dogmatic authority (two distinct topics!).https://cassyni-user-files-prod.s3.amazonaws.com/b7Hxg1g7yE4sMka9zev5k https://cassyni.com/slides/outline/6NZCkg3dQknJG9ECUY6WBF https://cassyni.com/events/6NZCkg3dQknJG9ECUY6WBF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/B8w18WSewnWbw1zvDJhuHY https://cassyni.com/events/6NZCkg3dQknJG9ECUY6WBF?videoPreview=1 Exploring the Challenges of ChatGPT in Educationnohttps://cassyni.com/events/6NZCkg3dQknJG9ECUY6WBF?videoPreview=12023-03-30T12:00:00+00:004885.16Hong Kong Baptist UniversityChatGPT presents both transformative potential and significant challenges within education, prompting a critical re-evaluation of pedagogical practices. The discussion frames generative AI tools as a continuation of technological evolution rather than an unprecedented revolution, akin to the internet's impact, yet acknowledges their disruptive capacity in specific professional domains, with an estimated 80% of workers having at least 10% of their tasks exposed to large language models. Key challenges addressed include the need for users to understand generative AI tools beyond black-box usage, the imperative to embrace and collaboratively learn with these technologies, the necessity to redesign assessments, and the importance of establishing robust legal, ethical, and privacy guidelines. Pedagogical approaches proposed include multi-deliverable assignments, incorporating action plans, AI tool usage logs, final submissions, and reflective essays to assess critical thinking and problem-solving. It is argued that while AI tools, such as ChatGPT and Midjourney, can enhance creativity and aid in initial idea generation or content refinement, they are not authoritative "gurus" and cannot resolve complex, assessive questions that lack unique answers. The core educational mission is thus heightened: fostering critical, collaborative thinking, balancing competing values, and preserving human interaction. The integration of AI literacy into curricula, for both students and educators, is identified as crucial for understanding inherent biases and ensuring responsible deployment. Future directions emphasize leveraging established learning science frameworks to study AI's impact on problem-based and design-based learning, alongside the development of personalized AI tutors and contextual tools for individualized student support. The ongoing concern centers on preventing intellectual irresponsibility, preserving human creativity, and maintaining social aspects of learning in an increasingly AI-driven landscape.https://cassyni-user-files-prod.s3.amazonaws.com/B8w18WSewnWbw1zvDJhuHY https://cassyni.com/slides/outline/S5AHqaP2BFGs3WrU4PWT7 https://cassyni.com/events/S5AHqaP2BFGs3WrU4PWT7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6XeaemWhKGcYZZeeDXYTgi https://cassyni.com/events/S5AHqaP2BFGs3WrU4PWT7?videoPreview=1 Doubling Moral Self-Cultivation: Digital Doppelgangers, Moral Deskiling, and Fragmented Identitynohttps://cassyni.com/events/S5AHqaP2BFGs3WrU4PWT7?videoPreview=12024-03-20T12:00:00+00:004498.92Hong Kong Baptist UniversityThis analysis examines the ethical implications of digital doppelgangers—AI-based digital replicas that mimic individuals’ personalities, behaviors, and moral judgments—focusing on their impact on moral self-cultivation. While prior discussions have addressed privacy, consent, autonomy, and identity concerns, this study interrogates how digital doppelgangers affect individuals’ moral development. Drawing on Shannon Vallor’s concept of moral deskilling, which arises when technology reduces opportunities to practice moral skills, the analysis argues that digital doppelgangers do not cause moral deskilling because they do not displace individuals from contexts requiring moral engagement. Instead, they enable users to delegate certain interactions, preserving opportunities for direct moral practice. However, digital doppelgangers neither enhance nor multiply moral cultivation, due to epistemic and phenomenological gaps that hinder the transfer of experiential moral learning from the doppelganger to the original person. Furthermore, digital doppelgangers create a “meta-choice environment” allowing selective engagement with circumstances, which fosters moral vices such as self-centeredness, moral arrogance, and closed-mindedness by encouraging individuals to prioritize self-chosen environments over diverse moral experiences. Additionally, the proxy nature of digital doppelgangers introduces epistemic and interpretative gaps that fragment coherent self-identity, complicating the formation of a unified narrative self essential for moral self-cultivation. This fragmentation risks narrative gaslighting, where multiple semi-autobiographical interactions mediated by doppelgangers undermine individuals’ authority over their self-narratives. Consequently, while digital doppelgangers do not directly impair moral skills, they pose significant challenges to the integrity of moral self-cultivation by promoting selective engagement and identity fragmentation.https://cassyni-user-files-prod.s3.amazonaws.com/6XeaemWhKGcYZZeeDXYTgi https://cassyni.com/slides/outline/6tMLVApVN1KBy8kXQ4doRf https://cassyni.com/events/6tMLVApVN1KBy8kXQ4doRf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6YfHgHDbY4mWpmEAR3jLea https://cassyni.com/events/6tMLVApVN1KBy8kXQ4doRf?videoPreview=1 Implicit LES of NACA 0018 Airfoil with Active Flow Controlnohttps://cassyni.com/events/6tMLVApVN1KBy8kXQ4doRf?videoPreview=12021-07-01T14:00:00+00:003130.76PyFRIn this work, high-order Computational Fluid Dynamics simulations are performed for a NACA 0018 airfoil with an active flow control slot at Reynolds numbers between $Re=1.25\cdot10^{5}$ and $Re=2.5\cdot10^{5}$ using the PyFR compressible flow solver. Results are compared to experiments as well as previous numerical simulation results. This interesting case involves steady slot-blowing out of a slot located at 5% chord, which has been found experimentally to either raise or lower aerodynamic loads depending on the blowing momentum coefficient. ILES simulation results of pressure distributions and resulting aerodynamic loads show superior accuracy compared to previous numerical simulation attempts, and demonstrate the first numerical result to resolve the non-linear lift curves seen in the experiments. In particular, the importance of accurately resolving the Laminar Separation Bubble, taking into account the 3D control slot, as well as the wind tunnel geometry was found to have a large impact on results. The results in this work indicate that a high-order turbulence-resolving solver with the ability to handle complex geometries is required in order to accurately predict loads for flow control cases such as this. Lastly, a PyFR plugin implementing an on-line flow controller that adjusts blowing slot jet momentum using a feedback loop is demonstrated with the purpose of serving as a test-bed for flow control algorithm development. https://cassyni-user-files-prod.s3.amazonaws.com/6YfHgHDbY4mWpmEAR3jLea https://cassyni.com/slides/outline/LDy9C9MCpoyUXYHZuKAnNZ https://cassyni.com/events/LDy9C9MCpoyUXYHZuKAnNZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JFKnoocAdnyYNTa8jPpo58 https://cassyni.com/events/LDy9C9MCpoyUXYHZuKAnNZ?videoPreview=1 Designs of acoustic metamaterials: From effective medium to deep learningnohttps://cassyni.com/events/LDy9C9MCpoyUXYHZuKAnNZ?videoPreview=12021-05-11T14:00:00+00:006243.8MetaMATAcoustic metamaterials have offered great opportunities to control acoustic wave propagation as desired. The intriguing property of an acoustic metamaterial is attributed to its unique effective property. Therefore, effective medium theory, a bridge connecting the response of the medium to the incident wave and the medium’s microstructure, provides design principles of new acoustic metamaterials. Recently, the blossoming of artificial intelligence enabled another efficient way of designing acoustic metamaterials. In this talk, I will start with a review our early contributions in deriving effective medium theories followed by showcases of our recent designs of acoustic metamaterials and their properties. Finally, I will introduce our most recent work on deep learning enabled design of acoustic cloak of invisibility.https://cassyni-user-files-prod.s3.amazonaws.com/JFKnoocAdnyYNTa8jPpo58 https://cassyni.com/slides/outline/WbaqAVwE3Rbu43ahvR7g45 https://cassyni.com/events/WbaqAVwE3Rbu43ahvR7g45/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LM5cFi79VzKxUf5Mtvr2tN https://cassyni.com/events/WbaqAVwE3Rbu43ahvR7g45?videoPreview=1 Tailoring thermal emission with metasurfacesnohttps://cassyni.com/events/WbaqAVwE3Rbu43ahvR7g45?videoPreview=12020-12-08T14:00:00+00:005168.96MetaMATWith the advent of fabrication and imaging at the nanoscale, many unexpected properties of thermal radiation have been explored in the last twenty years. The first part of the talk will be devoted to a review of key features including spatial and temporal coherence of incandescent sources. In the second part of the talk, recent results on an incandescent source that can be modulated beyond 10MHz, six orders of magnitude faster than commercially available hot membranes, will be presented.https://cassyni-user-files-prod.s3.amazonaws.com/LM5cFi79VzKxUf5Mtvr2tN https://cassyni.com/slides/outline/X6ESDBakUt9x3p7bWrQUKP https://cassyni.com/events/X6ESDBakUt9x3p7bWrQUKP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FQWhSz6EuL283fBi8gW3bC https://cassyni.com/events/X6ESDBakUt9x3p7bWrQUKP?videoPreview=1 Topological mode steering across wave physicsnohttps://cassyni.com/events/X6ESDBakUt9x3p7bWrQUKP?videoPreview=12020-06-09T14:00:00+00:004779.04MetaMATSteering waves around sharp bends and splitting their energy between different channels, in a robust and lossless manner, is of interest across many areas of engineering and physics. The seminal work of Mekis et. al [Phys. Rev. Lett. 18, 3787, 1996] in photonic crystals using cavity waveguides to perform this is now used widely in devices. A very active area of current research involves trying to use ideas originating in quantum mechanics, and from topological insulators, for similar purposes, but with the added potential of broadband performance, and enhanced robustness. In this presentation, I will relay the main principles of topological modes in classical wave systems and elucidate their benefits and shortcomings. Theoretical, computation and experimental results will be used to highlight a particular class of these insulators that contain passive elements and are solely reliant upon geometrical properties of the structured media.https://cassyni-user-files-prod.s3.amazonaws.com/FQWhSz6EuL283fBi8gW3bC https://cassyni.com/slides/outline/Fn5TYjVi4y8j6QnuYb2GTP https://cassyni.com/events/Fn5TYjVi4y8j6QnuYb2GTP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BnS83YgwYfnNqg2WV9rkPp https://cassyni.com/events/Fn5TYjVi4y8j6QnuYb2GTP?videoPreview=1 Uncovering the Potential of the Foot for Novel I/O Interfacesnohttps://cassyni.com/events/Fn5TYjVi4y8j6QnuYb2GTP?videoPreview=12021-08-24T04:00:00+00:003293.88The Auckland Bioengineering InstituteAugmented foot interfaces have been studied since the beginning of wearable computers. The world’s first wearable computer was an instrumented shoe that consisted of a toe operated switch with a wireless module. Since then, academic research and commercial products on augmented foot interfaces have been booming, with novel interfaces every year. However, there are still areas in the foot augmentation domain that have not been widely explored yet. My Ph.D. research aims to contribute new concepts that will complement previous research in the domain of foot augmentation. To accomplish this, first, I conducted a literature review classifying all the prior work, that helped identify three potential applications where foot augmentation devices can be beneficial. In my first application, I developed a smart shoe to detect acute stress during sedentary tasks, where foot augmentation acts as an input device. In the second application, I developed an output foot augmentation device to provide tickling stimulation that induces fun and causes laughter. As my third application, I present a novel input/output foot augmentation device that senses the Centre of Pressure, an important bio-mechanical parameter. The device was used to improve exercise posture while the wearer was performing squats and deadlifts. Finally, based on the outcome of my thesis work, I suggest design considerations for future research on augmented foot interfaces which will be helpful for HCI researchers and practitioners.https://cassyni-user-files-prod.s3.amazonaws.com/BnS83YgwYfnNqg2WV9rkPp https://cassyni.com/slides/outline/7P94713SpGVshbMGPBE95F https://cassyni.com/events/7P94713SpGVshbMGPBE95F/abstract https://cassyni-user-files-prod.s3.amazonaws.com/MacmdVqiKyRFDKDuXSuqie https://cassyni.com/events/7P94713SpGVshbMGPBE95F?videoPreview=1 Wave breaking and jet formation on axisymmetric surface gravity wavesnohttps://cassyni.com/events/7P94713SpGVshbMGPBE95F?videoPreview=12022-04-12T10:40:00+00:001693.08Water WavesAxisymmetric standing waves occur across a wide range of free surface flows. When these waves reach a critical height (steepness), wave breaking and jet formation occurs. For travelling surface gravity waves, the process of wave breaking is generally considered to limit wave height and reversible wave motion. In the ocean, the behaviour of directionally spread waves lies between the limits of purely travelling (2D) and axisymmetric (3D). Hence, understanding wave breaking and jet formation on axisymmetric surface gravity waves is an important step in understanding extreme and breaking waves in the ocean. We examine an example of axisymmetric wave breaking and jet formation colloquially known as the ‘spike wave’, created in the FloWave circular wave tank at the University of Edinburgh, UK. We generate this spike wave with maximum crest amplitudes of 0.15-6.0 m, with wave breaking occurring for crest amplitudes greater than 1.0 m. Unlike 2D travelling waves, wave breaking does not limit maximum crest amplitude, and our measurements approximately follow the jet height scaling proposed by Ghabacheet al. (2014, JFM) for cavity collapse. The spike wave is predominantly created by linear dispersive focusing, which forms a deep wave trough. This trough or cavity then collapses producing a jet, which is highly sensitive to the trough’s shape. The evolution of the jets that forming our experiments is predicted well by the hyperbolic jet model proposed by Longuet-Higgins (1983, JFM), previously applied to jets forming on bubbles at much smaller scalehttps://cassyni-user-files-prod.s3.amazonaws.com/MacmdVqiKyRFDKDuXSuqie https://cassyni.com/slides/outline/8NP1y7JitTkfRqJukDc3BT https://cassyni.com/events/8NP1y7JitTkfRqJukDc3BT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/64MCD65XonJgGYyYTFWAc6 https://cassyni.com/events/8NP1y7JitTkfRqJukDc3BT?videoPreview=1 Analysis of the Dynamics of Immersed Elastic Filaments in Stokes Flownohttps://cassyni.com/events/8NP1y7JitTkfRqJukDc3BT?videoPreview=12021-06-24T15:00:00+00:003451.44Partial Differential Equations and ApplicationsWe consider the problem of an elastic filament immersed in a 2D or 3D Stokes fluid. We first discuss the analysis of an immersed filament problem in a 2D Stokes fluid (the Peskin problem). We prove well-posedness and immediate regularization of the elastic filament configuration and discuss criteria for global existence. We will then discuss the immersed filament problem in a 3D Stokes fluid (the Slender Body problem). Here, it has not even been clear what the appropriate mathematical formulation of the problem should be. We propose a mathematical formulation for the Slender Body problem and discuss well-posedness for the stationary version of this problem. Furthermore, we prove that the Slender Body approximation, introduced by Keller and Rubinow in the 1980's and used widely in computation, provides an approximation to the Slender Body problem.https://cassyni-user-files-prod.s3.amazonaws.com/64MCD65XonJgGYyYTFWAc6 https://cassyni.com/events/3RtyWGqUVtDe2jbZjju3TK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5QECVAKEFgmgVCM7qo4j4r https://cassyni.com/slides/outline/Rf6nhfTyer4sewsMuwQgKw https://cassyni.com/events/Rf6nhfTyer4sewsMuwQgKw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AdQvcbMwaLrbLuQwakC8ez https://cassyni.com/events/Rf6nhfTyer4sewsMuwQgKw?videoPreview=1 Heat shield architecture for 21st century space missionsnohttps://cassyni.com/events/Rf6nhfTyer4sewsMuwQgKw?videoPreview=12020-12-11T14:00:00+00:002864.4Department of AeronauticsIn past Entry, Descent and Landing (EDL) missions, deceleration of a spacecraft has been achieved by means of fixed-geometry rigid heat shields. Their maximum diameter was constrained by the size of the launcher fairing, and this in turn has restricted the payload mass. Foldable aeroshells, stowed during launch and deployed before the entry manoeuvre, show potential for landing heavier payloads on the surface of a planet. In addition, they could be a versatile option for aerocapture manoeuvres and orbit insertion at the ice giants. In this talk I will give an overview of the research on mechanically deployable heat shields that has been carried out at Imperial College in recent years. The Hypersonic foldable Aeroshell for THermal protection using ORigami (HATHOR) concept consists of rigid Thermal Protection System (TPS) panels fitted between retractable ribs for the repeatable deployment of a high precision geometry. The talk will focus on the aerothermodynamic aspects of the problem, assessed through an in-house developed engineering model for heat transfer to a complex-geometry heat shield.https://cassyni-user-files-prod.s3.amazonaws.com/AdQvcbMwaLrbLuQwakC8ez https://cassyni.com/slides/outline/ALyS9qtpeHyRXYb97BTyc1 https://cassyni.com/events/ALyS9qtpeHyRXYb97BTyc1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7HyCpoCLuRgsmoT6ozZkgn https://cassyni.com/events/ALyS9qtpeHyRXYb97BTyc1?videoPreview=1 Segregation, interaction of species and related free boundary problemsnohttps://cassyni.com/events/ALyS9qtpeHyRXYb97BTyc1?videoPreview=12020-10-26T15:00:00+00:003523.68Partial Differential Equations and ApplicationsReaction-diffusion systems with strong interaction terms appear in many multi-species physical problems as well as in population dynamics, chemistry and material science. The qualitative properties of the solutions and their limiting profiles in different regimes have been at the center of the community's attention in recent years. A prototypical example appears when looking for solitary wave solutions for Bose-Einstein condensates of two (or more) different hyperfine states which overlap in space. Typically the forces between particles in the same state are attractive while those between particles in different states can be either attractive or repulsive. If the condensates repel, they eventually separate spatially giving rise to a free boundary. This phenomenon is called phase separation and has been described in recent literature, both physical and mathematical. One of the most interesting problems researchers investigate is when different phases of matter, populations, or clusters exist in a single space(i.e.in adjacent cells).Their interest focuses not only in how these different phases / populations / clusters interact with one another, but also on the properties of the boundaries separating them.The recent literature shows that the walls separating the different phases are geometrically tractable surfaces, as well as multiple junctions among them.This involves developing novel variational methods and geometric measure theory and free boundary tools.Relevant connections have been established with optimal partition problems involving spectral functionals.The classification of entire solutions and the geometric aspects of the nodal sets of solutions are of fundamental importance as well.We intend to focus on the most recent development of the theory in connection with problems featuring anomalous diffusions, long - range and non symmetric.https://cassyni-user-files-prod.s3.amazonaws.com/7HyCpoCLuRgsmoT6ozZkgn https://cassyni.com/slides/outline/MDGMHWeFhj5dCJ7a1He7BT https://cassyni.com/events/MDGMHWeFhj5dCJ7a1He7BT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CQF8MQFM6VUYc8Qd3BE8ra https://cassyni.com/events/MDGMHWeFhj5dCJ7a1He7BT?videoPreview=1 Mechano-Energetics of Dynamically-Impeded Cardiac Trabeculaenohttps://cassyni.com/events/MDGMHWeFhj5dCJ7a1He7BT?videoPreview=12021-10-19T03:00:00+00:002818.12The Auckland Bioengineering InstituteCardiac muscle contraction from coordinated force-length changes results in ventricular pressure volume loops. When subjecting isolated muscles to work-loop contractions that mimic the pressure volume loop, the length-change phases (shortening and re-stretching) are conventionally simplified to result in ‘flat-topped’ work-loops. Such simplification overlooks the dynamic nature of the cardiovascular load as the tissues may experience in vivo. In this talk, I present novel methods for mechanically loading isolated cardiac muscles with real-time models of the preload and afterload experienced by the heart. Using these loading methods, I address the following: Do isolated muscle samples produce more work under these model-based contraction methods? Do they contract more efficiently? These new methods reveal the limitations imposed by conventional, simplified, loading protocols. This project thus enables potential avenues for exploring the cardiac force length space, physiologically and pathophysiologically.https://cassyni-user-files-prod.s3.amazonaws.com/CQF8MQFM6VUYc8Qd3BE8ra https://cassyni.com/events/TdfammYC1KMYCRMQfXCLsf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BVY5aYWGo4kmoNj3Y7gxoY https://cassyni.com/events/UcuYdsoU5WcKvMjD4ixukh/seminar/qa https://cassyni.com/slides/outline/UcuYdsoU5WcKvMjD4ixukh https://cassyni.com/events/UcuYdsoU5WcKvMjD4ixukh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Ksq5FH1tjq8dE1fRnzv1Rx https://cassyni.com/events/UcuYdsoU5WcKvMjD4ixukh?videoPreview=1 The GRASP atomic structure code - current status, the CompAS collaboration and hopes for the futurenohttps://cassyni.com/events/UcuYdsoU5WcKvMjD4ixukh?videoPreview=12022-02-08T16:00:00+00:003267.16Computer Physics CommunicationsThe quality and resolution of solar, stellar, and other types of astrophysical spectra have improved to the extent that the accuracy and availability of atomic data is frequently a limiting factor in the interpretation of observations in astronomy. With the new generation of ground-based spectrographs and space missions, such as the recent CRIRES+ upgrade on the Very Large Telescope (VLT) and the James Webb Space Telescope (JWST), new demands are put on complete and accurate atomic data in the relatively unexplored infrared (IR) spectral regime. In particular, data on heavy, complex atomic species such as the various ionization stages of the Lanthanide and Actinide group of elements are needed for the interpretation of more exotic astrophysical events involving neutron-capture elements such as the Kilonova (KN) ejecta following the neutron-star merger observed in 2017. Analyses of such events require not only data of spectroscopic accuracy, e.g. for element identifications, but also complete data for accurate opacities in the radiative-transfer modeling to track e.g. the brightness evolution. Laboratory measurements, e.g. using ion/traps, beam-foil, or laser techniques, have been performed for isolated transitions and atoms, but no systematic laboratory studies exist or are currently in progress. Instead, the bulk of these atomic data must be calculated. To solve these new challenges, multiconfigurational (Dirac-) Hartree-Fock methods, either non-relativistic with Breit-Pauli corrections or fully relativistic, could be considered a promising way forward. The main advantage of these approaches is their general applicability to excited and open-shell systems, including open f- and g-shells, across the whole periodic table, thus allowing for the production of extensive atomic data sets with transition energies and probabilities. Additional physical properties of interest can readily be determined from the obtained wavefunctions. The accuracy of such calculations depends on the complexity of the shell structure and on the underlying adopted model for describing electron correlation. By systematically increasing the basis in large-scale calculations, as well as exploring different models for electron correlation, it is often possible to provide an estimate of the accuracy. In this talk I will describe our current, [open-source](https://github.com/compas ), community effort within the Computational Atomic Physics ([CompAS](https://compas.github.io )) collaboration, to build upon the important and acclaimed work on state-of-the-art multiconfigurational codes by Profs. Charlotte F Fischer and Ian P Grant, with a particular focus on the relativistic variant: the general-purpose relativistic atomic structure package, [GRASP](https://doi.org/10.1016/j.cpc.2018.10.032 ).https://cassyni-user-files-prod.s3.amazonaws.com/Ksq5FH1tjq8dE1fRnzv1Rx https://cassyni.com/slides/outline/3vaCfaztLhhTrCb5Xr21dX https://cassyni.com/events/3vaCfaztLhhTrCb5Xr21dX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BU4GvBYEUe2ierXEGgtesG https://cassyni.com/events/3vaCfaztLhhTrCb5Xr21dX?videoPreview=1 An Innovative Finite Volume Method for Discretizing Hyperbolic Systems of Conservations Lawsnohttps://cassyni.com/events/3vaCfaztLhhTrCb5Xr21dX?videoPreview=12022-09-19T14:00:00+00:003390.76Journal of Computational PhysicsThis work describes a novel subface flux-based Finite Volume (FV) method for discretizing multi- dimensional hyperbolic systems of conservation laws over general unstructured grids. The subface flux numerical approximation relies on the notion of simple Eulerian Riemann solver introduced in the sem- inal work [2]. The Eulerian Riemann solver is constructed from its Lagrangian counterpart by means of the Lagrange-to-Euler mapping. This systematic procedure ensures the transfer of good properties such as positivity preservation and entropy stability [2, 1]. In this framework, the conservativity and the entropy stability are no more locally face-based but result respectively from a node-based vectorial equation and a scalar inequation. The corresponding multi-dimensional FV scheme is characterized by an explicit time step condition ensuring positivity preservation and entropy stability. The application to gas dynamics provides an original multi-dimensional conservative and entropy-stable FV scheme wherein the numerical fluxes are computed through a nodal solver which is similar to the one designed for Lagrangian hydrodynamics [3]. We also observe that the present approach relies on an approximate Riemann solver for Eulerian gas dynamics characterized by naturally ordered wave speeds contrarily to the one introduced in [4]. The robustness and the accuracy of this novel FV scheme are assessed through various numerical tests. We observe its insensitivity to the numerical pathologies that plague classical face-based contact discontinuity preserving FV formulations.https://cassyni-user-files-prod.s3.amazonaws.com/BU4GvBYEUe2ierXEGgtesG https://cassyni.com/slides/outline/BLJGMqhkva1JLn7YVisk3X https://cassyni.com/events/BLJGMqhkva1JLn7YVisk3X/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Xe6PLsVeThgTrHMENuXF6v https://cassyni.com/events/BLJGMqhkva1JLn7YVisk3X?videoPreview=1 Evolving together, evolving apart: Measuring the fitness of rhizobial bacteria in and out of symbiosis with leguminous plantsnohttps://cassyni.com/events/BLJGMqhkva1JLn7YVisk3X?videoPreview=12021-12-16T15:00:00+00:002144.68New PhytologistMost plant–microbe interactions are facultative, with microbes experiencing temporally and spatially variable selection. How this variation affects microbial evolution is poorly understood. Given its tractability and ecological and agricultural importance, the legume–rhizobia nitrogen-fixing symbiosis is a powerful model for identifying traits and genes underlying bacterial fitness. New technologies allow high-throughput measurement of the relative fitness of bacterial mutants, strains and species in mixed inocula in the host, rhizosphere and soil environments. I consider how host genetic variation (G × G), other environmental factors (G × E), and host life-cycle variation may contribute to the maintenance of genetic variation and adaptive trajectories of rhizobia – and, potentially, other facultative symbionts. Lastly, I place these findings in the context of developing beneficial inoculants in a changing climate.https://cassyni-user-files-prod.s3.amazonaws.com/Xe6PLsVeThgTrHMENuXF6v https://cassyni.com/slides/outline/GmTXyzLR9y29ZLpQJJhhws https://cassyni.com/events/GmTXyzLR9y29ZLpQJJhhws/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XDHkC1QBPybaBUnwXLeRGa https://cassyni.com/events/GmTXyzLR9y29ZLpQJJhhws?videoPreview=1 Sequents and Treesnohttps://cassyni.com/events/GmTXyzLR9y29ZLpQJJhhws?videoPreview=12021-06-18T10:40:00+00:005264.92Logica UniversalisConsiders the methodology and techniques of sequent calculus to illustrate its use in proving a wide range of metatheoretical results Includes many results and their proofs that are often not well known or easily accessible Examines important and nonstandard generalized sequent calculi, like hypersequent and structured sequent calculi.https://cassyni-user-files-prod.s3.amazonaws.com/XDHkC1QBPybaBUnwXLeRGa https://cassyni.com/slides/outline/9MjUHjdYa6idoJdVk965Vo https://cassyni.com/events/9MjUHjdYa6idoJdVk965Vo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/YFAAkkAvDsULqiXH4MgKka https://cassyni.com/events/9MjUHjdYa6idoJdVk965Vo?videoPreview=1 Hardware-in-the-Loop testing and validation of AI/ML for In-Space Assemblynohttps://cassyni.com/events/9MjUHjdYa6idoJdVk965Vo?videoPreview=12022-06-08T15:00:00+00:003639.12Department of AeronauticsThe proliferation of reusable space vehicles has fundamentally changed how we inject assets into orbit and beyond, increasing the reliability and frequency of launches. Leading to the rapid development and adoption of new technologies into the Aerospace sector, such as computer vision (CV), machine learning (ML), and distributed networking. All these technologies are necessary to enable genuinely autonomous decision-making for space-borne platforms as our spacecraft travel further into the solar system, and our missions sets become more ambitious, requiring true “human out of the loop” solutions for a wide range of engineering and operational problem sets. Deployment of systems proficient at classifying, tracking, capturing, and ultimately manipulating orbital assets and components for maintenance and assembly in the persistent dynamic environment of space and on the surface of other celestial bodies, tasks commonly referred to as On-Orbit Servicing and In Space Assembly, have a unique automation potential. However, the large amounts of sensor data required to adequately train neural networks for these space domain tasks are either limited or non-existent, requiring alternate means of data collection/generation. Additionally, the wide-scale tools and methodologies required for hardware in the loop simulation, testing, and validation of these new technologies outside of multimillion-dollar facilities are largely in their developmental stages. This talk proposes a novel approach for simulating space-based computer vision sensing and robotic control using both physical and virtual reality testbeds. This methodology is designed to both be affordable and expandable, enabling hardware in the loop simulation and validation of space systems at large scales. While the specific computer vision models are narrowly focused on solving imagery problems found on orbit, this work can be expanded to solve any problem set that requires robust onboard computer vision, robotic manipulation, and free flight capabilities. https://cassyni-user-files-prod.s3.amazonaws.com/YFAAkkAvDsULqiXH4MgKka https://cassyni.com/slides/outline/QBDDnsZB9CFiCQ3GYkVszV https://cassyni.com/events/QBDDnsZB9CFiCQ3GYkVszV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Ef75oJ9UgnNSx3Pg2S1F8a https://cassyni.com/events/QBDDnsZB9CFiCQ3GYkVszV?videoPreview=1 Open Source Decarbonization for a Sustainable Worldnohttps://cassyni.com/events/QBDDnsZB9CFiCQ3GYkVszV?videoPreview=12022-08-22T17:00:00+00:002880.08ElsevierThe world is facing a climate emergency. We must reduce our reliance on fossil fuels and their export and, instead, develop renewable and efficient energy. Electrification of heating with heat pumps can radically reduce natural gas use, electrical vehicles cut the need for oil, and energy efficiency and renewable energy can help shoulder the greater demand this electrification causes, while cutting coal use, carbon emissions and resultant climate destabilization. Open source hardware design has proven to be an effective method to increase innovation and decrease costs of equipment. It can accelerate practical action and the implementation of policies and strategies to reduce our use of oil and gas. In this presentation the power of open source will be explained to show how it can improve the performance and decrease the costs of decarbonization technologies. This presentation will end with a description of the [HardwareX special issue on Open Source Decarbonization for a Sustainable World](https://www.journals.elsevier.com/hardwarex/forthcoming-special-issues/special-issue-on-open-source-decarbonization-for-a-sustainable-world). https://cassyni-user-files-prod.s3.amazonaws.com/Ef75oJ9UgnNSx3Pg2S1F8a https://cassyni.com/slides/outline/S9odyc9Gu2UUJ7KVuiMpR3 https://cassyni.com/events/S9odyc9Gu2UUJ7KVuiMpR3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5sBkEZm7TMCwMyKhUM4yAW https://cassyni.com/events/S9odyc9Gu2UUJ7KVuiMpR3?videoPreview=1 Brand-and-price for a multi-attribute Technician Routing and Scheduling Problemnohttps://cassyni.com/events/S9odyc9Gu2UUJ7KVuiMpR3?videoPreview=12021-02-11T16:05:01+00:00529.04Operations Research ForumNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/5sBkEZm7TMCwMyKhUM4yAW https://cassyni.com/slides/outline/MiMvAGXxaxTMCvZ75uqhpy https://cassyni.com/events/MiMvAGXxaxTMCvZ75uqhpy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/V1kAoZNdj3udZCiQyw1wiW https://cassyni.com/events/MiMvAGXxaxTMCvZ75uqhpy?videoPreview=1 Evolution and Functional Potential of Gut Microbiota in Honeybees: A Comparative Metagenomic Approachnohttps://cassyni.com/events/MiMvAGXxaxTMCvZ75uqhpy?videoPreview=12024-11-12T01:00:00+00:00684.16Microbiome Virtual International ForumStudying gut microbiota evolution across animals is crucial for understanding microbiome ecology and evolution. However, this is hampered by the lack of high-resolution genomic data, especially from natural systems. Honeybees, with their specialized gut microbiota and well-known host ecology and evolutionary history, offer an ideal system for studying this evolution. Using shotgun metagenomics on 200 honeybee workers from five species, we recovered thousands of metagenome-assembled genomes, identifying several novel bacterial species. Our analysis revealed that microbial communities were mainly host-specific. Yet, we found specialist and generalist bacteria, even among bacterial species within the same genera, with notable variation between host species. Intriguingly, some generalists exhibited host-specificity only at the strain level, suggesting recent host-switch events. Contrary to expectations, we found no evidence of co-diversification between honeybee species and their gut microbiota. Instead, the gut microbiota displayed dynamic patterns of gains, losses, and replacements that could influence key functional traits, such as the degradation of pollen-derived pectin—an important process for honeybee nutrition and health. These findings advance our understanding of host specificity in gut microbiota-host associations and show that ancient interactions can be maintained in the absence of co-diversification. We also highlight the importance of other factors, such as host distribution and ecology, in driving microbiome diversity. Beyond offering new insights into gut microbiota evolution, our study uncovers the functional potential of the gut microbiota of Asian honeybees, which remained underexplored despite the crucial role of these pollinators in their native ecosystem.https://cassyni-user-files-prod.s3.amazonaws.com/V1kAoZNdj3udZCiQyw1wiW https://cassyni.com/events/V85yrXEqApmBhW5a3nhSEy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NQ2aSxmWeVS5yMEghVNcwp https://cassyni.com/events/BqPqEbbTooP2MQZ5aM5Lh3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/F273QYAQySURLRrUaBMCGE https://cassyni.com/slides/outline/7PZPpSmjrgPmtkoHfhJmYZ https://cassyni.com/events/7PZPpSmjrgPmtkoHfhJmYZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8Y9jmeYjAW42LigpUxhuoL https://cassyni.com/events/7PZPpSmjrgPmtkoHfhJmYZ?videoPreview=1 Transient cognitive impacts of oxygen deprivation caused by catch-and-release anglingnohttps://cassyni.com/events/7PZPpSmjrgPmtkoHfhJmYZ?videoPreview=12025-02-28T12:00:00+00:001337.72Royal Society PublishingVertebrate brain function is particularly sensitive to the effects of hypoxia, with even brief periods of oxygen deprivation causing significant brain damage and impaired cognitive abilities. This study is the first to investigate the cognitive consequences of hypoxia in fish, specifically induced by exhaustive exercise and air exposure, conditions commonly encountered during catch-and-release (C&R) practices in recreational fishing. Angling exerts substantial pressure on inland fish populations, underscoring the need for sustainable practices like C&R. While C&R survival rates are generally high, understanding its sublethal impacts is crucial for evaluating the practice's ethical and ecological sustainability. We examined the effects of these stressors on the cognitive function of 238 rainbow trout, using the Free Movement Pattern Y-maze method to assess working memory through navigational search patterns during free exploration sessions. Our results showed that air exposure led to short-term (3-4 hours post-treatment) but transient impairments in working memory, with no long-term cognitive deficits observed at 1 week and 1 month post-treatment. These findings emphasise the high tolerance of fish to hypoxia and support the sustainability of C&R as a tool in fisheries management.https://cassyni-user-files-prod.s3.amazonaws.com/8Y9jmeYjAW42LigpUxhuoL https://cassyni.com/slides/outline/FnduqKoS8BfG2GJnDnQSJy https://cassyni.com/events/FnduqKoS8BfG2GJnDnQSJy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EgTMLt8GnYajR9QcYRWC7G https://cassyni.com/events/FnduqKoS8BfG2GJnDnQSJy?videoPreview=1 Experiences from the Microbiota Vault Pilot Projectnohttps://cassyni.com/events/FnduqKoS8BfG2GJnDnQSJy?videoPreview=12025-09-11T00:50:00+00:00789.44Microbiome Virtual International ForumBuilt on the “Collect-Preserve-Enable” concept, the 2022-24 Microbiota Vault pilot proved that a global back-up for human microbiome diversity is technically and legally feasible. A –80 °C/N₂ biobank in Zurich, now receives material from eight partner collections (five human gut, three fermented-food) and secured ~2 000 specimens spanning five continents. Sixteen harmonised cryo- and lyophilisation SOPs, validated on infant-to-adult faecal samples over one year, ensure consistent preservation quality. Minimal metadata and a cloud 16S-V4 analysis pipeline deliver immediate research utility, while standard MTAs and a consortium agreement provide equitable governance. With launch-phase milestones met, the project is ready to scale (2025-27) and aims now to further expand with higher geographic coverage.https://cassyni-user-files-prod.s3.amazonaws.com/EgTMLt8GnYajR9QcYRWC7G https://cassyni.com/events/Tdn5EHbjcm4Sn2ZAqxLnAy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4EEUs3wny7k1C9GVnSpfSN https://cassyni.com/slides/outline/GmsshS4iCNv3kWGRapnLRB https://cassyni.com/events/GmsshS4iCNv3kWGRapnLRB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CerJqnXGrCv2JhrLbeREvz https://cassyni.com/events/GmsshS4iCNv3kWGRapnLRB?videoPreview=1 Octopus.ac: A New Academic Publishing Model To Improve Research Culturenohttps://cassyni.com/events/GmsshS4iCNv3kWGRapnLRB?videoPreview=12023-06-15T03:00:00+00:005328.72UKRNOctopus.ac is a new UKRI funded research publishing model, designed to encourage, enable, and reward best practice using 21st century tools. Free to read, free to publish, and entirely open source, this is a new way to register research that is fast, free and fair. During this session we will discuss some of the problems with the established publishing model and research culture, how Octopus.ac seeks to solve them by espousing the principles of open research, and the challenges that Octopus.ac faces in a landscape dominated by incentive structures based around impact. To frame the current state of research culture with regard to publishing, Dr Pen-Yuan Hsing will outline the findings of An Evaluation of the Research and Publishing Ecosystem, drawing on insights from surveys and interviews with researchers from a wide range of disciplines. The impact driven landscape has created a research culture where open research practises are viewed by many as not beneficial, or even detrimental to career advancement, meaning Octopus.ac’ development as a system must be guided its ability to serve as a solution to these concerns. Moving away from the traditional journal paper, Octopus.ac uses smaller publication units which more closely align with the research process. The platform is designed to be the new primary research record for the academic community, to create a new culture of collaboration and recognition, improving access to research outputs and resetting the academic incentive structure to reward best practice and recognise specialisation. To highlight how this new model is being received by the academic community, we will also explore the challenges, concerns and benefits that researchers identify when introduced to Octopus.ac, based on the insights gained via a series of workshops held by Evangelia Kotsiliti over the past few months. Participants should gain a deeper understanding of the problems facing research culture, how Octopus.ac aims to provide a solution, and the perceptions of researchers regarding publishing, both in general and in relation to Octopus.ac specifically.https://cassyni-user-files-prod.s3.amazonaws.com/CerJqnXGrCv2JhrLbeREvz https://cassyni.com/slides/outline/9N9p1BMqcWcXzU5X2fAhy7 https://cassyni.com/events/9N9p1BMqcWcXzU5X2fAhy7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KZu9Nj4jbFjFV12YTjLn6J https://cassyni.com/events/9N9p1BMqcWcXzU5X2fAhy7?videoPreview=1 Enhancing Searchability: Archiving Practice Researchnohttps://cassyni.com/events/9N9p1BMqcWcXzU5X2fAhy7?videoPreview=12021-11-15T03:00:00+00:006367.52UKRNThis workshop covered challenges and issues involved with documenting and archiving practice research. Some of the questions this panel aimed to address included: - How can we ensure that practice research is fully searchable and visible in the public domain? - Are university repositories able to host the research findings of practice research - projects run within, or in collaboration with, universities in the UK? - What kinds of practices can we design and share that allow for the most effective and efficient means of sharing the research findings of work in this area? - How do we consider the ways in which disciplinary differences warrant different considerations in devising systems (technological or otherwise) for archiving and disseminating practice research?https://cassyni-user-files-prod.s3.amazonaws.com/KZu9Nj4jbFjFV12YTjLn6J https://cassyni.com/slides/outline/QgAg6UsT1czoULQxEhPwFj https://cassyni.com/events/QgAg6UsT1czoULQxEhPwFj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Ba44G2MSwfunpeXzvijDwt https://cassyni.com/events/QgAg6UsT1czoULQxEhPwFj?videoPreview=1 Complex but intriguing iron sulfide-based autotrophic denitrificationnohttps://cassyni.com/events/QgAg6UsT1czoULQxEhPwFj?videoPreview=12025-02-18T10:00:00+00:003840.24ElsevierTreating wastewater to a high standard before discharge into lakes, rivers, and seas is essential for achieving the Sustainable Development Goals (SDGs) and maintaining environmental and ecological integrity. In this context, iron sulfide-based autotrophic denitrification (ISAD) presents a promising alternative to conventional heterotrophic denitrification, offering effective simultaneous removal of nitrogen and phosphorus from wastewater. I will present our findings on the ISAD process applied to the treatment of secondary effluent from municipal wastewater treatment plants. Building on these results, I propose a next-generation sustainable wastewater treatment approach — NEO-GREEN (Iron Sulfide-Based Biotechnology for Advanced Wastewater Treatment). This innovative process has the potential to harness bioenergy from wastewater, facilitate resource recovery (phosphorus and iron), and achieve simultaneous removal of nutrients and emerging contaminants. Several intriguing and challenging phenomena exist in iron sulfide-based autotrophic denitrification systems. For instance, the crystallinity of iron sulfides significantly influences both chemical and biochemical denitrification processes. Understanding these mechanisms not only provides valuable insights into nitrogen, sulfur, iron, phosphorus, and carbon cycling in natural environments but also contributes to our understanding of life's resilience in harsh conditions.https://cassyni-user-files-prod.s3.amazonaws.com/Ba44G2MSwfunpeXzvijDwt https://cassyni.com/slides/outline/Dod9w9V3KwYy8r6TwGzNS9 https://cassyni.com/events/Dod9w9V3KwYy8r6TwGzNS9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JjwPgVVYuSrWRXnPCEtAMk https://cassyni.com/events/Dod9w9V3KwYy8r6TwGzNS9?videoPreview=1 The ANTARES detector: two decades of neutrino searches in the Mediterranean sea.nohttps://cassyni.com/events/Dod9w9V3KwYy8r6TwGzNS9?videoPreview=12025-06-21T09:00:00+00:002326.76Physics ReportsInterest for studying cosmic neutrinos using deep-sea detectors has increased after the discovery of a diffuse flux of cosmic neutrinos by the IceCube collaboration and the possibility of wider multi-messenger studies with the observations of gravitational waves. The ANTARES detector was the first neutrino telescope in seawater, operating successfully in the Mediterranean Sea for more than a decade and a half. All challenges related to the operation in the deep sea were accurately addressed by the collaboration. Deployment and connection operations became smoother over time; data taking and constant re-calibration of the detector due to the variable environmental conditions were fully automated. A wealth of results on the subject of astroparticle physics, particle physics and multi-messenger astronomy have been obtained, despite the relative modest size of the detector, paving the way to a new generation of larger undersea detectors. This review summarizes the efforts by the ANTARES collaboration that made the possibility to operate neutrino telescopes in seawater a reality and the results obtained in this endeavor.https://cassyni-user-files-prod.s3.amazonaws.com/JjwPgVVYuSrWRXnPCEtAMk https://cassyni.com/events/5Pd69VT6mXiW9TWpDaeoF3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/94hRhpSUekf3b4FRs6dan https://cassyni.com/events/U8UvWEH2rwU3RC1JqjHvG5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8dmNEQJ7Vg6GmAR9UyFuMx https://cassyni.com/slides/outline/EJL1D6ALa7xZn1Ybw3wWXF https://cassyni.com/events/EJL1D6ALa7xZn1Ybw3wWXF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4jMAowQrDFsfy5BrvxTHoL https://cassyni.com/events/EJL1D6ALa7xZn1Ybw3wWXF?videoPreview=1 Black Hole Soft Hair and Dynamical Horizonsnohttps://cassyni.com/events/EJL1D6ALa7xZn1Ybw3wWXF?videoPreview=12025-08-25T22:00:00+00:001448.84Annals of PhysicsIn this seminar, quasilocal Brown-York charges are derived that coincide in the large sphere limit with the conserved supertranslation hair and superrotation charges introduced by Hawking, Perry and Strominger. Based on this derivation, a general scenario is outlined in which a non-rotating dynamical black hole completely evaporates after its collapse due to particle creation effects, whereby a genuine one-way traversable event horizon is never formed, but merely a two-way traversable dynamical (resp. future trapping) horizon. The formation of such a dynamical horizon has the consequence that quasilocal energy transported by the considered charges, and thus information, can continuously escape through the black hole horizon to infinity; a mechanism which, as is argued, could possibly prevent information loss once the black holeformation and evaporation process comes to an end. https://cassyni-user-files-prod.s3.amazonaws.com/4jMAowQrDFsfy5BrvxTHoL https://cassyni.com/events/9q9gJic5HgWkzZ2M29VBDX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/sGtP5FKukqkaQ3oVWj8Kp https://cassyni.com/events/4thFxWeiJTuBgcS4odNFSM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PL8U2T7uN9fHmBGF39Utir https://cassyni.com/events/R9JeyAh7hbXywxM2zQsP5X/abstract https://cassyni-user-files-prod.s3.amazonaws.com/SyU5Js9h8zackn1pvT94ii https://cassyni.com/slides/outline/HkAfg8oraJgQX6sA4d7bhP https://cassyni.com/events/HkAfg8oraJgQX6sA4d7bhP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2mFiLwzLWRzr8jmeziMhBk https://cassyni.com/events/HkAfg8oraJgQX6sA4d7bhP?videoPreview=1 Gut dysbiosis and immunoresistance in oncologynohttps://cassyni.com/events/HkAfg8oraJgQX6sA4d7bhP?videoPreview=12026-09-15T12:05:00+00:001201.6Microbiome Virtual International ForumEvidence from the past decade demonstrates that gut dysbiosis is a potentially modifiable contributor to immunotherapy resistance in cancer, creating a need to incorporate patients’ gut microbial ecology into both oncological research and clinical care. We review gut microbial signatures associated with treatment response across cancer types and evaluate stool- and blood-based biomarkers of dysbiosis, including microbial metabolites, host inflammatory signatures, and composite tools such as TOPOSCORE that aim to characterise individual gut ecology. We then consider how these biomarkers could be integrated into clinical research and practice. Combined with medical history and lifestyle factors, gut microbial biomarkers may help identify patients most likely to benefit from microbiota-centred interventions and improve treatment outcomes. Clinical translation will require prospective validation and standardisation of trial design, sample collection and processing, analytical methods, and reporting. These advances could enable more precise, microbiome-informed strategies for overcoming immunotherapy resistance in cancer.https://cassyni-user-files-prod.s3.amazonaws.com/2mFiLwzLWRzr8jmeziMhBk https://cassyni.com/events/LCrEcxjkiNvQe1kkmtkTJM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/98D74rg6RgW4qdGs5wCSVk https://cassyni.com/slides/outline/CoGHVrcK9KFCsX8TH1ybpH https://cassyni.com/events/CoGHVrcK9KFCsX8TH1ybpH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PzaRLnghRB9i5uTJ5h11dx https://cassyni.com/events/CoGHVrcK9KFCsX8TH1ybpH?videoPreview=1 Owning, renting, and environmental proactivity – The role of housing tenure in hypothetical housing decisionsnohttps://cassyni.com/events/CoGHVrcK9KFCsX8TH1ybpH?videoPreview=12025-09-11T09:00:00+00:00459.28Sage PublishingBackground: Past research indicates that for older individuals, transitioning to a home environment better suited to their needs reduces physical, psychological, and social risks, and may even impact the rate of institutionalization. Tenants, compared to homeowners, are subject to different conditions that influence their decisions to relocate, which can either encourage or inhibit them in their pursuit of environmental proactivity. Objectives: This study investigates whether tenants make relocation decisions based on different factors than do owners. For this purpose, hypothetical relocation decisions are made under the influence of certain ownership constellations. Data and Methods: The dataset consists of 264 participants. They were asked about home ownership and then presented with housing vignettes (factorial survey) to indicate how likely they would be to move to a new apartment. The data were analyzed using group comparisons and zero-inflated models. Results: Tenants favor new apartments if their current dwelling is larger than the new one, and if they haven’t lived in their current home for a long time. In contrast, owners prefer the new apartment to have a central location. Both groups consider rent, proximity to kin, and a senior-friendly bathroom as important for the new apartment, with rent being more important to tenants than to those who are currently owners. Discussion: In both groups, we identified predictors that can be interpreted as barriers to environmental proactivity. The results add to the large body of literature on social inequality in old age. https://cassyni-user-files-prod.s3.amazonaws.com/PzaRLnghRB9i5uTJ5h11dx https://cassyni.com/slides/outline/8r75F1x131jnELNBAUKzr1 https://cassyni.com/events/8r75F1x131jnELNBAUKzr1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XdLYRFyhMbC4QtwKR4wRAN https://cassyni.com/events/8r75F1x131jnELNBAUKzr1?videoPreview=1 Kinship as a double-edged sword: Relatedness among burying beetle larvae enhances growth but increases mortalitynohttps://cassyni.com/events/8r75F1x131jnELNBAUKzr1?videoPreview=12025-11-08T09:00:00+00:001217.28Royal Society PublishingTheoretical and empirical considerations suggest that relatedness can have complex effects on social life. While high relatedness may promote sibling cooperation and altruism through indirect fitness benefits, it can also intensify competition if siblings share similar needs and competitive strategies. Moreover, low genetic diversity in highly related groups may heighten susceptibility to pathogens. Hence, due to these potential opposing effects, the consequences of relatedness for offspring fitness within a family context are not fully understood. Here, we investigated how relatedness among interacting offspring influences their fitness in the burying beetle Nicrophorus vespilloides, a species exhibiting facultative parental care, with larvae developing in a microbially rich and challenging environment. To assess offspring effects without parental influence, we raised larvae in the absence of care, thereby eliminating parental buffering and exposing them to a more stressful environment. We compared the growth and survival rates of broods consisting of full siblings and broods with unrelated larvae and found both benefits and costs of relatedness. Larvae gained weight more rapidly in the early stages when surrounded by siblings but suffered higher mortality later in development. These findings suggest that high relatedness facilitates cooperative effects but comes at a cost, potentially reducing social immunocompetence.https://cassyni-user-files-prod.s3.amazonaws.com/XdLYRFyhMbC4QtwKR4wRAN https://cassyni.com/slides/outline/4QKt48A3tccMUhgp7cBUS9 https://cassyni.com/events/4QKt48A3tccMUhgp7cBUS9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HP6tmRTC3Zsf8jSN5exv9t https://cassyni.com/events/4QKt48A3tccMUhgp7cBUS9?videoPreview=1 Numerical solutions of resistive finite-pressure magnetohydrodynamic equilibria for stellarator and non-axisymmetric toroidal plasmasnohttps://cassyni.com/events/4QKt48A3tccMUhgp7cBUS9?videoPreview=12025-12-06T06:00:00+00:001135.76Computer Physics CommunicationsA hybrid spectral/finite-element code is developed to numerically solve the resistive finite-pressure magnetohydrodynamic equilibria without the necessity of postulating nested magnetic flux surfaces in the non-axisymmetric toroidal systems. The adopted approach integrates a hyperbolic parallel damping equation for pressure updating, along with a dynamic resistive relaxation for magnetic field. To address the non-axisymmetry in toroidal geometry, a pseudo flux mapping is employed to relate the axisymmetric computational domain to the physical domain. On the computational mesh, an isoparametric C1-continuous triangular element is utilized to discretize the poloidal plane, which is complemented with a Fourier decomposition in the toroidal direction. The versatility of the code is demonstrated through its application to several different non-axisymmetric toroidal systems, including the inherently three-dimensional equilibria in stellarators, the helical-core equilibrium states in tokamak plasmas, and the quasi-single-helicity states in a reversed-field pinch.https://cassyni-user-files-prod.s3.amazonaws.com/HP6tmRTC3Zsf8jSN5exv9t https://cassyni.com/events/QewH4nCTHkEq1CgNvqqAtD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/N2ZiyCZAwNdCYWZm3JdgrS https://cassyni.com/slides/outline/vkPT9jnrzj6gWWNGAWUdK https://cassyni.com/events/vkPT9jnrzj6gWWNGAWUdK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JTyyV8qrHLgXiHzufWek8e https://cassyni.com/events/vkPT9jnrzj6gWWNGAWUdK?videoPreview=1 Decision dynamics in the jamming avoidance response of weakly electric fish: impact of conspecific motionnohttps://cassyni.com/events/vkPT9jnrzj6gWWNGAWUdK?videoPreview=12026-05-18T04:00:00+00:00814.04Royal Society PublishingWave-type weakly electric fish sense in dark environments using a quasi-sinusoidal electric organ discharge (EOD). When two fish have similar EOD frequency (EODf), each fish changes its frequency to avoid signal interference. In this ‘jamming avoidance response’ (JAR), fish must decide whether to increase or decrease EODf using amplitude and phase information from the combined EODs. The JAR has typically been examined in stationary fish, but during natural interactions, swimming produces noisy amplitude modulations (AMs) that could impact JAR decisions. To test this, we delivered artificial signals to Eigenmannia virescens mimicking a dynamically approaching conspecific (2–20 Hz AM noise) with lower EODf (i.e. the correct JAR comprises an EODf increase). Noise intensity did not significantly affect maximum JAR magnitude (p = 0.784) nor the time to a correct JAR (p = 0.883). However, noise improved accuracy when signal amplitude was low (p = 0.037) but reduced accuracy when amplitude was high (p = 0.008), suggesting that motion-generated AMs can benefit or impair JAR encoding depending on signal saliency. We also observed that short-latency decisions were biased slightly towards an incorrect JAR despite the noise benefit, and that the classic JAR algorithm combined with a biased random-walk model for low-amplitude conditions can explain the JAR dynamics produced by motion-generated AMs.https://cassyni-user-files-prod.s3.amazonaws.com/JTyyV8qrHLgXiHzufWek8e https://cassyni.com/slides/outline/MC9SiL2obJ2ZJmakssDn7F https://cassyni.com/events/MC9SiL2obJ2ZJmakssDn7F/abstract https://cassyni-user-files-prod.s3.amazonaws.com/599uFxckTvGrGfpbGSo1xA https://cassyni.com/events/MC9SiL2obJ2ZJmakssDn7F?videoPreview=1 Transparency, the ultimate camouflage? Background dependency and influence of background lightnessnohttps://cassyni.com/events/MC9SiL2obJ2ZJmakssDn7F?videoPreview=12026-06-22T10:00:00+00:001634.68Royal Society PublishingTransparency reduces prey detectability by predators and occurs in diverse aquatic and terrestrial organisms. Previous studies have shown that in open waters, transparency level decreases as depth increases, suggesting that intermediate transparency may be more protective in dimmer conditions, an untested prediction. Another widespread camouflage strategy is background matching: background-matching specialists are better protected than generalists on their specific background, but this creates stronger background dependency. This raises the question of whether transparency could outperform background matching, thereby reducing background dependency. In a citizen-science computer-based predation experiment, we asked human participants to locate a butterfly in different backgrounds (vegetation, soil, trunk). We manipulated butterfly coloration (uniform coloration specialist or generalist), transparency level (opaque, semi-opaque, transparent), background lightness, apparent butterfly size, and distance to the predator’s attention point to test their effect on protection. We found that intermediate transparency protects better in dimmer conditions, as predicted. Butterflies appearing smaller (in size or viewed from a greater distance), or creating stronger edge disruption were better protected, particularly when transparent. Butterflies closer to the attention point or on less complex backgrounds were less protected, unless more transparent. Finally, transparency outperformed specialist and generalist uniform colorations, suggesting transparency can free prey from background dependency. https://cassyni-user-files-prod.s3.amazonaws.com/599uFxckTvGrGfpbGSo1xA https://cassyni.com/events/GFfQFVZZCiVFrMJ5NnAQhT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/H3r8SEQzpNK51hKZxmB5iN https://cassyni.com/events/ApXkjySnNgQBTV3qmsAci1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GLScjkgZJHM4L61oJyUfQz https://cassyni.com/slides/outline/EJdrU1q6169ZPZns38shhF https://cassyni.com/events/EJdrU1q6169ZPZns38shhF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5rwFTPNopAJGE9BYMb9SRC https://cassyni.com/events/EJdrU1q6169ZPZns38shhF?videoPreview=1 Nurturing Change Through Growing UKRN Projectsnohttps://cassyni.com/events/EJdrU1q6169ZPZns38shhF?videoPreview=12024-01-18T03:00:00+00:005464.32UKRNMaking positive change in research culture isn’t simple: it needs different strategies and approaches. UKRN is doing just that through a number of new projects. Our first webinar of the New Year is a great opportunity to hear about how we’re nurturing changes in research culture through projects that work from the grassroots and across higher-level strategy. Find out how we are harnessing our community and reaching out beyond it, using strategies that range from using narrative theory to meta-research.https://cassyni-user-files-prod.s3.amazonaws.com/5rwFTPNopAJGE9BYMb9SRC https://cassyni.com/slides/outline/6tunmm8DRDqitzGQ5G1yHF https://cassyni.com/events/6tunmm8DRDqitzGQ5G1yHF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/54YJVBTDDpLbkhDhGdCLCW https://cassyni.com/events/6tunmm8DRDqitzGQ5G1yHF?videoPreview=1 Bringing climate technologies to market for the energy transition and industrial decarbonizationnohttps://cassyni.com/events/6tunmm8DRDqitzGQ5G1yHF?videoPreview=12024-12-11T16:00:00+00:001579.28Risk Sciences#### Practice Insights: Maryam Golnaraghi ***[Risk Sciences](https://www.keaipublishing.com/en/journals/risk-sciences/)*** aims to foster diverse, multidisciplinary insights in risk sciences, bridging theory and practice through a series of academic activities. This talk is part of the "Practice Insights" track of this series, highlights key lessons from real-world experiences, offering valuable perspectives to researchers and practitioners alike. The speaker Maryam Golnaraghi is one of the leading thought leaders on climate change in the global insurance industry and her talk was insightful to cover from technical issues of climate risk management to policy-wise solutions for the insurance industry. Maryam’s 25-year career has been dedicated to pioneering climate resilience, climate risk management and decarbonization initiatives. Her experience spans senior executive roles, entrepreneurship, and international advisory positions across the private sector, public sector, and the United Nations. Maryam is currently the Director of Climate Change and Environment at The Geneva Association, the think tank for the global insurance industry. In this role, she collaborates with CEOs and executive teams of the largest re/insurance companies and builds cross-sectoral partnerships to boost the industry's contributions to addressing climate change. This speech record is an excerpt from Maryam's keynote speech for the [Risk Sciences Colloquium – International Seminar on Climate Risks](https://www.keaipublishing.com/en/journals/risk-sciences/event/risk-sciences-colloquium-international-seminar-on-climate-risks/), to be held on January 16, 2025, in Seoul, South Korea. A more in-depth version of this lecture has been presented at the forum. https://cassyni-user-files-prod.s3.amazonaws.com/54YJVBTDDpLbkhDhGdCLCW https://cassyni.com/slides/outline/MDggzxNYk8yXPTZbHoijem https://cassyni.com/events/MDggzxNYk8yXPTZbHoijem/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VrB1PzmMDYN32dSX1tqU1c https://cassyni.com/events/MDggzxNYk8yXPTZbHoijem?videoPreview=1 argNorm: Normalization of antibiotic resistance gene annotations to the Antibiotic Resistance Ontology (ARO)nohttps://cassyni.com/events/MDggzxNYk8yXPTZbHoijem?videoPreview=12024-12-04T00:30:00+00:00282.0Microbiome Virtual International ForumCurrently available and frequently used tools for annotating antimicrobial resistance genes (ARGs) in genomes and metagenomes provide results using inconsistent nomenclature. This makes the comparison of different ARG annotation outputs challenging. The comparability of ARG annotation outputs can be improved by mapping gene names and their categories to a common controlled vocabulary such as the Antibiotic Resistance Ontology (ARO). We developed argNorm, a command line tool and Python library, to normalize all detected genes across 6 ARG annotation tools (8 databases) to the ARO. argNorm also adds information to the outputs using the same ARG categorization so that they are comparable across tools. argNorm is available as an open-source tool at: https://github.com/BigDataBiology/argNorm. It can also be downloaded as a PyPI package and is available on Bioconda and as an nf-core module.https://cassyni-user-files-prod.s3.amazonaws.com/VrB1PzmMDYN32dSX1tqU1c