https://cassyni.com/events/F2t54fuLBttkkJayGTmWWy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8i8rHNKbs2sFaGGP63CHLS https://cassyni.com/events/Mwz9psUZjfaGPtrntJtDXT/seminar/qa https://cassyni.com/slides/outline/Mwz9psUZjfaGPtrntJtDXT https://cassyni.com/events/Mwz9psUZjfaGPtrntJtDXT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QJ8RCYoB3V4hbT3iuX67sC https://cassyni.com/events/Mwz9psUZjfaGPtrntJtDXT?videoPreview=1 Epistemic Logics with Quantification Over Epistemic Operators: Decidability and Expressivenessnohttps://cassyni.com/events/Mwz9psUZjfaGPtrntJtDXT?videoPreview=12023-07-19T14:00:00+00:003005.96Logica UniversalisThe optimal balance between decidability and expressiveness is a big problem of logical systems, in particular, of quantified epistemic logics (QELs). On the one hand, decidability is a very significant characteristic of logics that allows us to use such logics in the framework of artificial intelligence. On the other hand, QELs have important expressive capabilities that should not be lost when we construct decidable fragments of these logics. QELs are known to be much more expressive than first-order logics. One important example of their extra expressive power is that they allow us to distinguish between de dicto and de re readings of epistemic sentences. It is clear that such capabilities should be preserved as much as possible in decidable fragments. In this paper, we consider extensions of QELs that include quantification over modalities. Denote this extensions by QELs. QELs allows us to make more subtle distinctions between de dicto and de re readings of epistemic sentences, and we also should keep these new features as much as possible in decidable fragments. It is known that there are not much interesting decidable QELs. The situation with QELs is the same. But in recent years (after 2018), we have obtained a variety of decidable QELs constructed in different ways. We distinguish between (1) the approach in which for every undecidable QEL and for every variant of its decidable fragment, a specific proof is constructed, and (2) the approach in which a class of decidable QELs is obtained using general tools and a uniform method for all QELs of this class. In this paper, we compare the results of these approaches.https://cassyni-user-files-prod.s3.amazonaws.com/QJ8RCYoB3V4hbT3iuX67sC https://cassyni.com/slides/outline/TP9RT27Dy4bPfn8zBW4Z7T https://cassyni.com/events/TP9RT27Dy4bPfn8zBW4Z7T/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QRenxmiJ7Xpnznap4EhAmt https://cassyni.com/events/TP9RT27Dy4bPfn8zBW4Z7T?videoPreview=1 High-pressure characterization of Indium oxides for water splitting applicationsnohttps://cassyni.com/events/TP9RT27Dy4bPfn8zBW4Z7T?videoPreview=12021-06-10T12:00:00+00:003129.76Discover Applied SciencesWe have studied the electronic properties at ambient pressure and under high pressure of InVO4, InNbO4, and InTaO4 powders, three candidate materials for hydrogen production by means of photocatalytic water splitting using solar energy. A combination of optical absorption and resistivity measurements and band structure calculations have allowed us to determine that these materials are wide band-gap semiconductors with a band-gap energy of 3.62(5), 3.63(5), and 3.79(5) eV for InVO4, InNbO4, and InTaO4, respectively. The last two compounds are indirect band-gap materials, and InVO4 is a direct band-gap material. The pressure dependence of the band-gap energy and the electrical resistivity have been determined too. In the three compounds, the band gap opens under compression until reaching a critical pressure, where a phase transition occurs. The structural transition triggers a band-gap collapse larger than 1.2 eV in the three materials, being the abrupt decrease in the band-gap energy related to an increase in the pentavalent cation coordination number. The phase transitions also cause changes in the electrical resistivity, which can be correlated with changes induced by pressure in the band structure. An explanation to the reported results is provided based upon ab initio calculations. The conclusions attained are of significance for technological applications of the studied oxides.https://cassyni-user-files-prod.s3.amazonaws.com/QRenxmiJ7Xpnznap4EhAmt https://cassyni.com/slides/outline/HztBoHr2S5vfTRb6fiFL4d https://cassyni.com/events/HztBoHr2S5vfTRb6fiFL4d/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NqgVb45AXbupSikYJoymz6 https://cassyni.com/events/HztBoHr2S5vfTRb6fiFL4d?videoPreview=1 Novel Ligands/Catalysts in Asymmetric Organic Synthesisnohttps://cassyni.com/events/HztBoHr2S5vfTRb6fiFL4d?videoPreview=12023-08-18T16:00:00+00:009224.24Thieme GroupLigands/catalysts have played a crucial role in modern synthetic chemistry, enabling chemists to develop numerous new transformations with excellent control of the chemo-, regio-, stereo-, and/or enantio-selectivity. During recent decades, a large variety of novel ligands/catalysts have been developed, greatly enlarging the toolbox of chemists for chiral organic synthesis, and a large number of challenging transformations have been realized. https://cassyni-user-files-prod.s3.amazonaws.com/NqgVb45AXbupSikYJoymz6 https://cassyni.com/events/78ctnFcUn1jjAx8quA6MK3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UsM8YRQCLoAspq7cM5my74 https://cassyni.com/slides/outline/GWwNfEuT7iG12hbypHZvBf https://cassyni.com/events/GWwNfEuT7iG12hbypHZvBf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/R6T9Knh9L6phGASdEVn8nA https://cassyni.com/events/GWwNfEuT7iG12hbypHZvBf?videoPreview=1 Data-Free and Data-Driven Uncertainty Quantification in Turbulent Flow Simulationsnohttps://cassyni.com/events/GWwNfEuT7iG12hbypHZvBf?videoPreview=12021-06-02T10:00:00+00:003447.16Data-Centric Engineering JournalFluid simulations and predictions of turbulent motions play a critical role in many fluid flow scenarios but particularly when the flow is prone to separation. Despite continued advances in high-fidelity turbulent flow simulations, closure models based on the Reynolds-Averaged Navier-Stokes (RANS) equations are projected to remain in use for considerable time to come, especially when rapid responses are required or large number of conditions need to be studied. However, it is common knowledge that RANS predictions are corrupted by epistemic model-form uncertainty to a degree which is unknown a-priori. Hence, to obtain a computational framework of predictive utility, a model-form Uncertainty Quantification (UQ) framework is indispensable. UQ enables the characterization of the potential errors in the simulations and leads to prudent estimates of the impact of turbulence assumptions on the quantity of interest. Over the last several years we have developed an approach that uses a spectral decomposition of the modeled Reynolds-Stress Tensor (RST) which is the building block of all RANS closure. This strategy allows for the introduction of decoupled perturbations into the baseline intensity (kinetic energy), shape (eigenvalues), and orientation (eigenvectors) of the Reynolds stresses. Within this perturbation framework, we look for a-priori known limiting physical bounds. Since these bounds are universal, they can be used to constrain uncertainty estimates in any predictive flow scenario. Thus, even in the absence of relevant training data, we can maximize the spectral perturbations in order to obtain conservative uncertainty intervals. The approach has been proven to be useful in a variety of applications. On the other hand, any reference data (experiments or high-fidelity resolved turbulence simulations) can be used to further constrain the uncertainty estimates using commonly available data assimilation techniques. This provides a data-driven path towards UQ estimates. We will demonstrate our framework on canonical flow problems using two common data-driven approaches, random forest regression and deep neural networks. We consider a database of high-fidelity simulation data for the flow over a separated flows and compare the resulting uncertainty estimates to conventional RANS closures and available experimental data.https://cassyni-user-files-prod.s3.amazonaws.com/R6T9Knh9L6phGASdEVn8nA https://cassyni.com/events/XLFPUbjmGeEzbwpqSG67M7/seminar/qa https://cassyni.com/slides/outline/XLFPUbjmGeEzbwpqSG67M7 https://cassyni.com/events/XLFPUbjmGeEzbwpqSG67M7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HdJtT7BCM9expXhRUyApnA https://cassyni.com/events/XLFPUbjmGeEzbwpqSG67M7?videoPreview=1 Tumor cell metastasis: Modeling the long and treacherous journey in the circulation and escape at the metastatic sitenohttps://cassyni.com/events/XLFPUbjmGeEzbwpqSG67M7?videoPreview=12023-06-02T15:00:00+00:003980.08Journal of Fluid MechanicsMore than 90% of the mortality due to cancer is attributable to metastatic disease, yet we have at best a limited understanding of the barriers faced by a tumor cell as it is convected by blood flow from the primary tumor to the remote metastatic site. Our group has focused on developing physical models that address many of these barriers including: 1) arrest in the remote microcirculation either by adhesion or trapping, 2) survival while still inside the vessel against the stresses of fluid flow and immune cell attack, and 3) transmigration across the endothelial monolayer. The stresses experienced by the tumor cell and the respective roles of tumor cell stiffness and adhesion, endothelial permissiveness or resistance to invasion, and nuclear deformations leading to changes in cellular phenotype are all factors that combine to determine the outcome of metastatic seeding: death, proliferation, or dormancy with the potential for later transition to a proliferative state. In this presentation I will track the steps of the metastatic cascade and demonstrate how physical and computational models can shed light on these rate limiting processes.https://cassyni-user-files-prod.s3.amazonaws.com/HdJtT7BCM9expXhRUyApnA https://cassyni.com/events/Jz4uS95XhZKuXy3efaMZ7s/seminar/qa https://cassyni.com/slides/outline/Jz4uS95XhZKuXy3efaMZ7s https://cassyni.com/events/Jz4uS95XhZKuXy3efaMZ7s/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8PRKeoCie2duFUfjDqcFUJ https://cassyni.com/events/Jz4uS95XhZKuXy3efaMZ7s?videoPreview=1 Presentation of EAJ Issue 13/1 - May 22ndnohttps://cassyni.com/events/Jz4uS95XhZKuXy3efaMZ7s?videoPreview=12023-05-22T15:00:00+00:004548.64European Actuarial JournalThe seminar is chaired by Tim Boonen and Julien Trufin.https://cassyni-user-files-prod.s3.amazonaws.com/8PRKeoCie2duFUfjDqcFUJ https://cassyni.com/slides/outline/Hzk5E9GbRHJ2ijXFH2wngM https://cassyni.com/events/Hzk5E9GbRHJ2ijXFH2wngM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JKSGfmb1g3BJkadDC9o8YE https://cassyni.com/events/Hzk5E9GbRHJ2ijXFH2wngM?videoPreview=1 What Is Turbulence? Turbulent Fluid Dynamics are Everywherenohttps://cassyni.com/events/Hzk5E9GbRHJ2ijXFH2wngM?videoPreview=12021-03-19T12:00:00+00:001798.6Brunton LabTurbulent fluid dynamics are literally all around us. This video describes the fundamental characteristics of turbulence with several examples from nature and from engineering. We discuss how turbulent fluids are unsteady, three-dimensional, mixing, and multiscale. We also describe how the Reynolds number in the Navier-Stokes equations controls this complexity.https://cassyni-user-files-prod.s3.amazonaws.com/JKSGfmb1g3BJkadDC9o8YE https://cassyni.com/events/Us1NFBW95MUWF1MGtaBUdB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/ML9nrnEUdhYzjAKHAYRMeW https://cassyni.com/slides/outline/TsiA9pD6CSNMaFXGnbi9pH https://cassyni.com/events/TsiA9pD6CSNMaFXGnbi9pH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/51n3xs8LQVNaXvzdAEPN2J https://cassyni.com/events/TsiA9pD6CSNMaFXGnbi9pH?videoPreview=1 Cradle to Cradle Innovations – Concept and Opportunities for Closed-Loop Supply Chainsnohttps://cassyni.com/events/TsiA9pD6CSNMaFXGnbi9pH?videoPreview=12023-02-20T22:00:00+00:003164.0Faculty of Business and EconomicsUnder the global topic of Circular Economy, different strategies and concepts are currently being discussed for the realisation of a circular economy that conserves resources in connection with adapted production processes (input) and makes materials and resources in already used products (output) available again for further production cycles. The discussed concepts differ among other things by their claim or radicalness and the discussion circles between Eco-Efficiency and Eco-Effectiveness and. The Cradle2Cradle approach belongs to the latter and places high demands on the innovation system due to the requirement that waste should not be generated in the first place. As part of a project for the German Federal Ministry of Construction, we are currently investigating the possibilities of introducing the C2C approach on a broad regional scale. In a previous (qualitative) study, we first tried to better understand the barriers and challenges associated with the implementation of this ambitious approach at the level of manufacturers. As an interim conclusion, it can be seen that the consistent implementation of the C2C approach in companies, industries and regions must go hand in hand with a considerable rethinking of value creation processes among all actors involved, a visionary will to lead in decision-making, and broad acceptance among recipients or users of the products/solutions. https://cassyni-user-files-prod.s3.amazonaws.com/51n3xs8LQVNaXvzdAEPN2J https://cassyni.com/slides/outline/E3ZErg6Pucrsw54ZsvMk5T https://cassyni.com/events/E3ZErg6Pucrsw54ZsvMk5T/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NHQYEsC2ToYSDYuWJWvPM8 https://cassyni.com/events/E3ZErg6Pucrsw54ZsvMk5T?videoPreview=1 Critical Casimir Effect: Exact Resultsnohttps://cassyni.com/events/E3ZErg6Pucrsw54ZsvMk5T?videoPreview=12023-04-05T15:00:00+00:003339.96Physics ReportsIn any medium there are fluctuations due to temperature or due to the quantum nature of its constituents. If a material body is immersed in such a medium, its shape and the properties of its constituents modify the properties of the surrounding medium and its fluctuations. If in the same medium there is a second body then — in addition to all direct interactions between them — the modifications due to the first body influence the modifications due to the second body. This mutual influence results in a force between these bodies. If the excitations of the medium, which mediate the effective interaction between the bodies, are massless, this force is long-ranged and nowadays known as a Casimir force. If the fluctuating medium consists of a confined electromagnetic field in a vacuum, one speaks of the quantum mechanical Casimir effect. In the case that the order parameter of material fields fluctuates – such as differences of number densities or concentrations – and that the corresponding fluctuations of the order parameter are long-ranged, one speaks of the critical Casimir effect. This holds, e.g., in the case of systems which undergo a second-order phase transition and which are thermodynamically located near the corresponding critical point, or for systems with a broken continuous symmetry exhibiting Goldstone mode excitations. Here we review the currently available exact results concerning the critical Casimir effect in systems encompassing the one-dimensional Ising, XY, and Heisenberg models, the two-dimensional Ising model, the Gaussian and the spherical models, as well as the mean-field results for the Ising and the XY model. Special attention is paid to the influence of the boundary conditions on the behavior of the Casimir force. We present results both for the case of classical critical fluctuations if the system possesses a critical point at a non-zero temperature, as well as the case of quantum systems undergoing a continuous phase transition at zero temperature as a function of certain parameters. As confinements, we consider the film, the sphere–plane, and the sphere–sphere geometries. We discuss systems governed by short-ranged, by subleading long-ranged (i.e., of the van der Waals type), and by leading long-ranged interactions. In order to put the critical Casimir effect into the proper context and in order to make the review as self-contained as possible, basic facts about the theory of phase transitions, the theory of critical phenomena in classical and quantum systems, and finite-size scaling theory are recalled. Whenever possible, a discussion of the relevance of the exact results towards an understanding of available experiments is presented. The eventual applicability of the present results for certain devices is pointed out, too.https://cassyni-user-files-prod.s3.amazonaws.com/NHQYEsC2ToYSDYuWJWvPM8 https://cassyni.com/slides/outline/GWoG66L26udNJ1Y8RcGNoP https://cassyni.com/events/GWoG66L26udNJ1Y8RcGNoP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VPNDifQvw38Z7kLdeHLaiS https://cassyni.com/events/GWoG66L26udNJ1Y8RcGNoP?videoPreview=1 New Developments in Scientific Collaboration Technohttps://cassyni.com/events/GWoG66L26udNJ1Y8RcGNoP?videoPreview=12023-05-04T17:00:00+00:004348.17Every year, millions of academic seminars and thousands of research conferences take place. This large scale dissemination of knowledge has been happening for centuries, is complementary to the published literature, and much of it is now recorded. However, sifting through millions of hours of recorded research isn't very practical. How can we make these videos searchable, citable, and a core part of the future of academic publishing? In this talk I explore cutting-edge ideas and concepts. TooWrite is a digital platform that seeks to transform the process of scientific writing into an experience that is faster, healthier, and more accessible to researchers at all career stages. This lightning talk begins by following our founder journey and the creation of TooWrite - starting with two academics with a problem to solve, all the way to being acquired and hired by world-leading publisher, Springer Nature - and ends with a look at what’s coming next for TooWrite! PeerRef is a journal-independent open peer review platform. Its goals are to make peer review open, make peer review more researcher-centric, and eliminate the need for repeated peer review in successive journals. In this talk, I discuss how technology and new processes can improve peer review. There is a growing need for reliable data on Open Science practices to better understand researcher behaviour, and to understand the effectiveness of policies – of institutions, funders and publishers – at increasing adoption of Open Science [1]. In 2022 PLOS launched ‘Open Science Indicators’, (OSI) an initiative that tracks adoption of Open Science practices – such as sharing data, code, protocols and preprints – over time in the scholarly literature [2]. PLOS developed requirements for an OSI measurement framework underpinned by six guiding principles [3] and then selected DataSeer as a partner to deliver OSI using an artificial intelligence supported method. The initial results [4] analyse adoption levels across approximately 60,000 articles published in PLOS journals and approximately 7,000 comparator articles in PubMed Central. Articles were published between the start of 2019 and the end of June 2022. New results are being released in March 2023, and then each quarter. The results show that rates of data sharing, code sharing and preprint posting are increasing between 2019 and 2022. The results also reveal differences in adoption – and potential for adoption – between research fields and geographies as well as infrastructure (data, code and preprint repositories/ servers) used, enabling analysis of trends in different communities of researchers. The data and methods are being shared openly [5] to engage stakeholders in a conversation about how we can use quantitative, longitudinal evidence on Open Science practices to support increased adoption of Open Science globally. The word "metaverse" means different things to different people - including those who are working to create it. A mistake is to think of it as a single type of product or a single grouping of functionality; In reality, it will be something that arrives gradually and evolutionarily as the Internet continues to develop, rather than with the bang of a product launch. At its heart, the metaverse is about services on the Internet becoming more spatial and more interoperable. Spatial considerations and connecting mathematical models to one another have been at the heart of computational scientific disciplines for decades. So in many respects, computational scientists are already creating what could be thought of as pieces of a metaverse. In this talk, I shall discuss some of these scientific pieces of the metaverse, the value of communicating ideas spatially, some of the capabilities Hadean is working on, and where the future might take us.https://cassyni-user-files-prod.s3.amazonaws.com/VPNDifQvw38Z7kLdeHLaiS https://cassyni.com/events/975CPqd9X3KrXyMDsSekMK/seminar/qa https://cassyni.com/slides/outline/975CPqd9X3KrXyMDsSekMK https://cassyni.com/events/975CPqd9X3KrXyMDsSekMK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FaZBYRJyL4bwQ7ANGKe5EN https://cassyni.com/events/975CPqd9X3KrXyMDsSekMK?videoPreview=1 Electrochemical oxidation of Pt(111) beyond the place-exchange modelnohttps://cassyni.com/events/975CPqd9X3KrXyMDsSekMK?videoPreview=12023-05-03T13:00:00+00:002809.04Electrochimica ActaOxide formation plays an important role in the degradation of Pt electrocatalysts. However, the exact oxide structure and reaction mechanism are not fully understood. Here, we used in situ surface X-ray diffraction experiments to resolve the oxide formation at a Pt(111) model electrode at potentials near the onset of the oxygen evolution reaction. Fast experiments are possible by using X-ray photons with a high kinetic energy in combination with a large 2D detector. By employing very low potential sweep rates we obtain a more ordered oxidized surface compared to literature data from potential step experiments. This demonstrates that the oxidation process is strongly governed by the reaction kinetics. The increased surface order enables us to disentangle two subsequent oxidation process; initially the place-exchange process, followed by the formation of a partially disordered oxide in which still 50% of the surface atoms reside on sites commensurate to the Pt(111) surface. The reduction experiments indicate that the place-exchange process is structurally reversible, whereas the disordered oxide causes the surface roughening observed during potential cycling. Despite the increased surface order, oxide superstructures are not observed. These results provide important insights in the oxidation and degradation process of Pt(111), which are valuable for the design of improved electrocatalysts and they rationalize operating procedures.https://cassyni-user-files-prod.s3.amazonaws.com/FaZBYRJyL4bwQ7ANGKe5EN https://cassyni.com/slides/outline/BaKDdFrmiL6LtupnR8ZP5F https://cassyni.com/events/BaKDdFrmiL6LtupnR8ZP5F/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8uq9XpbGok4LyKmiR6HEpN https://cassyni.com/events/BaKDdFrmiL6LtupnR8ZP5F?videoPreview=1 Thermodynamics of unfolding mechanisms of pseudoknotted RNA from a coarse-grained loop-entropy model and absorbance/fluorescence measurementsnohttps://cassyni.com/events/BaKDdFrmiL6LtupnR8ZP5F?videoPreview=12022-06-23T09:00:00+00:002999.44Journal of Biological PhysicsPseudoknotted RNA molecules play important biological roles that depend on their folded structure. To understand the underlying principles that determine their thermodynamics and folding/unfolding mechanisms, we carried out a study on a variant of the mouse mammary tumor virus pseudoknotted RNA (VPK), a widely studied model system for RNA pseudoknots. Our method is based on a coarse-grained discrete-state model and the algorithm of PK3D (pseudoknot structure predictor in three-dimensional space), with RNA loops explicitly constructed and their conformational entropic effects incorporated. Our loop entropy calculations are validated by accurately capturing previously measured melting temperatures of RNA hairpins with varying loop lengths. For each of the hairpins that constitutes the VPK, we identified alternative conformations that are more stable than the hairpin structures at low temperatures and predicted their populations at different temperatures. Our predictions were validated by thermodynamic experiments on these hairpins. We further computed the heat capacity profiles of VPK, which are in excellent agreement with available experimental data. Notably, our model provides detailed information on the unfolding mechanisms of pseudoknotted RNA. Analysis of the distribution of base-pairing probability of VPK reveals a cooperative unfolding mechanism instead of a simple sequential unfolding of first one stem and then the other. Specifically, we find a simultaneous “loosening” of both stems as the temperature is raised, whereby both stems become partially melted and co-exist during the unfolding process. (Joint work with Ke Tang, Jorjethe Roca, Rong Chen and Anjum Ansari)https://cassyni-user-files-prod.s3.amazonaws.com/8uq9XpbGok4LyKmiR6HEpN https://cassyni.com/events/PvYwtyYn68rvw4kzg44Yr1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KKjFNsuw9b4Rk4GeoJML6a https://cassyni.com/events/PvYwtyYn68rvw4kzg44Yr1?videoPreview=1 Bioengineering for Global Health webinar (BioGloW)nohttps://cassyni.com/events/PvYwtyYn68rvw4kzg44Yr1?videoPreview=12022-05-13T14:00:00+00:005095.16Nature Reviews BioengineeringThe Bioengineering for Global Health webinar (BioGloW) brings together researchers, healthcare providers, policy makers, and scientific editors to discuss the impact of bioengineering research on global health challenges and future directions for improving equity in access to healthcare, research and publishing. From the design and local manufacturing of vaccines, therapeutics and point-of-care diagnostic tools, to international collaborations, policy making, funding decisions and equitable access. An exciting discussion about how bioengineering research can positively impact global health.https://cassyni-user-files-prod.s3.amazonaws.com/KKjFNsuw9b4Rk4GeoJML6a https://cassyni.com/slides/outline/JVRJPTS1G6mrYCWm594krZ https://cassyni.com/events/JVRJPTS1G6mrYCWm594krZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Qk7CRD6FjR4seaj2XWEDzn https://cassyni.com/events/JVRJPTS1G6mrYCWm594krZ?videoPreview=1 Modelling bounded nanoscale thin filmsnohttps://cassyni.com/events/JVRJPTS1G6mrYCWm594krZ?videoPreview=12023-05-30T13:00:00+00:001956.68Cassyni SeminarsThe effect of confining walls on the fluctuation of a nanoscale thin film’s free surface is studied using stochastic thin-film equations (STFEs). Two canonical boundary conditions are employed to reveal the influence of the confinement: (1) an imposed contact angle and (2) a pinned contact line. A linear stability analysis provides the wave eigenmodes, after which thermal-capillary-wave theory predicts the wave fluctuation amplitudes. Molecular dynamics (MD) simulations are performed to test the predictions, and a Langevin diffusion model is proposed to capture oscillations of the contact lines observed in MD simulations. Good agreement between the theoretical predictions and the MD simulation results is recovered, and it is discovered that confinement can influence the entire film. Notably, a constraint on the length scale of wave modes is found to affect fluctuation amplitudes from our theoretical model, especially for 3D films. This opens up challenges and future lines of inquiry.https://cassyni-user-files-prod.s3.amazonaws.com/Qk7CRD6FjR4seaj2XWEDzn https://cassyni.com/events/Ru9N5i8sqy5h2n3E31vVGZ/seminar/qa https://cassyni.com/slides/outline/Ru9N5i8sqy5h2n3E31vVGZ https://cassyni.com/events/Ru9N5i8sqy5h2n3E31vVGZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HqdNtb16YmtnvDPLZ2Qa3Y https://cassyni.com/events/59uz8zxqQjpRtnawku19P3/seminar/qa https://cassyni.com/slides/outline/59uz8zxqQjpRtnawku19P3 https://cassyni.com/events/59uz8zxqQjpRtnawku19P3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DUWay8xAE1rRHNainTdLNJ https://cassyni.com/events/59uz8zxqQjpRtnawku19P3?videoPreview=1 Why don't we share data and code? Perceived barriers and benefits to public archiving practicesnohttps://cassyni.com/events/59uz8zxqQjpRtnawku19P3?videoPreview=12023-08-01T16:00:00+00:002344.8Royal Society PublishingThe biological sciences community is increasingly recognizing the value of open, reproducible and transparent research practices for science and society at large. Despite this recognition, many researchers fail to share their data and code publicly. This pattern may arise from knowledge barriers about how to archive data and code, concerns about its reuse, and misaligned career incentives. Here, we define, categorize and discuss barriers to data and code sharing that are relevant to many research fields. We explore how real and perceived barriers might be overcome or reframed in the light of the benefits relative to costs. By elucidating these barriers and the contexts in which they arise, we can take steps to mitigate them and align our actions with the goals of open science, both as individual scientists and as a scientific community.https://cassyni-user-files-prod.s3.amazonaws.com/DUWay8xAE1rRHNainTdLNJ https://cassyni.com/events/4Acn3dfnXpiHE2kwevXpa9/seminar/qa https://cassyni.com/slides/outline/4Acn3dfnXpiHE2kwevXpa9 https://cassyni.com/events/4Acn3dfnXpiHE2kwevXpa9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TpcJvKqvLc9Kcxew1aQj5g https://cassyni.com/events/4Acn3dfnXpiHE2kwevXpa9?videoPreview=1 Session 3: Low-speed wind tunnel testingnohttps://cassyni.com/events/4Acn3dfnXpiHE2kwevXpa9?videoPreview=12023-10-05T12:30:00+00:005178.04Brahmal Vasudevan Institute for Sustainable Aviation at Imperial College London**Chair: Huub Timmermans, Netherlands Aerospace Centre**https://cassyni-user-files-prod.s3.amazonaws.com/TpcJvKqvLc9Kcxew1aQj5g https://cassyni.com/events/EYEU1zFokSLhkY45g2UiFf/seminar/qa https://cassyni.com/slides/outline/EYEU1zFokSLhkY45g2UiFf https://cassyni.com/events/EYEU1zFokSLhkY45g2UiFf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VfxNioc2Npzfs39GDxFK1x https://cassyni.com/events/EYEU1zFokSLhkY45g2UiFf?videoPreview=1 Session 3: Lay Summary Toolkit (for Clinical Trialists and Methodologists)nohttps://cassyni.com/events/EYEU1zFokSLhkY45g2UiFf?videoPreview=12023-07-14T12:30:00+00:00729.12Institute for Cancer ResearchNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/VfxNioc2Npzfs39GDxFK1x https://cassyni.com/slides/outline/9bkRZ9nZMrogMSLjfYmiXX https://cassyni.com/events/9bkRZ9nZMrogMSLjfYmiXX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4MkrzbaigdzrVArbSfyL6J https://cassyni.com/events/9bkRZ9nZMrogMSLjfYmiXX?videoPreview=1 Research veracity/integritynohttps://cassyni.com/events/9bkRZ9nZMrogMSLjfYmiXX?videoPreview=12023-09-05T18:30:00+00:003381.44SCIWRITERReproducibility checklists are very useful things to remind us of the things that we should remember when publishing our results. They are required by major funders and many journals, but they are also difficult to remember, harder to fill out, and can be quite annoying. We introduce the SciScore tool to help the authors remember the common features of these checklists and enable authors to generate several of these checklists with one quick run of the tool. We hope you join us in this webinar and we hope you learn how this can make the researcher's lives just a bit easier. Researchers are increasingly asked to share the datasets that underpin their research. These requests might come from an academic journal, your institution, or – scariest of all – your funding agency. Deciding which datasets you're expected to share and which repositories are most suitable is a challenging task. DataSeer uses Natural Language Processing to help researchers navigate data sharing mandates: we identify the datasets associated with a manuscript, and give guidance on where and how that data should be shared. Research papers and protocol organization in labs and companies often lack detailed instructions for repeating experiments. protocols.io is an open access method repository and a platform for scientists to create step-by-step, interactive and dynamic protocols that can be run on mobile or web. Researchers can share protocols with lab mates, collaborators, the scientific community or make them public, with ease and efficiency. Real time communication and interaction keep protocols up to date with versioning, forking, Q&A, and troubleshooting. Public sharing also helps to give researchers credit, recognizing them for the painstaking work of method development.https://cassyni-user-files-prod.s3.amazonaws.com/4MkrzbaigdzrVArbSfyL6J https://cassyni.com/slides/outline/XpxEkYR4WpebFQrpPseafP https://cassyni.com/events/XpxEkYR4WpebFQrpPseafP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JdB4cDA7cgT2ydp5evh366 https://cassyni.com/events/XpxEkYR4WpebFQrpPseafP?videoPreview=1 Building Brainsnohttps://cassyni.com/events/XpxEkYR4WpebFQrpPseafP?videoPreview=12023-09-11T15:30:00+00:002699.28HiPEDS CentreCarver Mead introduced the concept of neuromorphic, or brain-inspired, computing in the 1980s, drawing an analogy between the equations that govern the flow of electrons in a transistor operating in its sub-threshold region and those that govern the flow of ions in the ion channels in a neuron. Since then the field has diversified to include a range of analogue and digital approaches, and novel device technologies, that in some way take inspiration from the brain to explore alternative models of computation to those employed in mainstream computing. The SpiNNaker project at the University of Manchester, UK, is currently the world’s largest neuromorphic computing platform, incorporating over a million ARM processor cores connected through a novel communications fabric developed to support the very high degree of connectivity found between neurons in the brain. SpiNNaker was developed primarily to support real-time models of brain regions with the objective of contributing to the scientific Grand Challenge of understanding the principles of operation of the brain as an information processing system. It is openly available to researchers around the world under the auspices of the EU Flagship Human Brain Project.https://cassyni-user-files-prod.s3.amazonaws.com/JdB4cDA7cgT2ydp5evh366 https://cassyni.com/events/StUCHhwp8F7ZrK9UPPwawF/seminar/qa https://cassyni.com/slides/outline/StUCHhwp8F7ZrK9UPPwawF https://cassyni.com/events/StUCHhwp8F7ZrK9UPPwawF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/dmtZ5RAcRw58ubSnD8Y5c https://cassyni.com/events/StUCHhwp8F7ZrK9UPPwawF?videoPreview=1 Celebrating Editorial Impact in 2023nohttps://cassyni.com/events/StUCHhwp8F7ZrK9UPPwawF?videoPreview=12023-12-14T14:00:00+00:003502.28Topics at the heart of our communityThis year, Editors have worked on a number of initiatives that have made an impact on their journals; from Editorial Board development, to supporting growth, increasing diversity, and the impact of new collections- we have a lot to celebrate!https://cassyni-user-files-prod.s3.amazonaws.com/dmtZ5RAcRw58ubSnD8Y5c https://cassyni.com/slides/outline/KUk8bTEwYNojMjd1RX5rXF https://cassyni.com/events/KUk8bTEwYNojMjd1RX5rXF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/L2tr7sa4U6jr14RfZba3oc https://cassyni.com/events/KUk8bTEwYNojMjd1RX5rXF?videoPreview=1 Granular Matter in Spacenohttps://cassyni.com/events/KUk8bTEwYNojMjd1RX5rXF?videoPreview=12023-06-12T12:00:00+00:003244.12Granular MatterThe investigation of granular matter benefits from experiments in microgravity in several ways and may be categorized into three regimes of increasing density: (1) Granular gases [1] are dilute systems and subject to sedimentation which can be avoided in microgravity. Their agitation by magnetic excitation allows for the study of cooling, velocity distributions and the onset of particle agglomeration. (2) Granular fluids [2] are denser than granular gases and are monitored by scattering techniques. On Earth, granular fluids are anisotropic and inhomogeneous. In microgravity, agitated homogeneous granular fluids can be prepared for densities up to the jamming transition. (3) Granular packings [3] close to the jamming transisionexperience a large pressure gradient on Earth which is absent in microgravity. Hence, sound transmission can be studied at very low confinement. Similarly, microgravityoffers unique opportunities for the rheology on dense granular systems.https://cassyni-user-files-prod.s3.amazonaws.com/L2tr7sa4U6jr14RfZba3oc https://cassyni.com/slides/outline/5ebDJK8FFZJFiZAJWqjSnR https://cassyni.com/events/5ebDJK8FFZJFiZAJWqjSnR/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9vNjGbZAuYH6geScntp2CN https://cassyni.com/events/5ebDJK8FFZJFiZAJWqjSnR?videoPreview=1 Forward-backward steps in signal processingnohttps://cassyni.com/events/5ebDJK8FFZJFiZAJWqjSnR?videoPreview=12022-05-05T12:30:00+00:002724.48Journal on Image and Video ProcessingThis talk provides an overview of the forward-backward (FB) algorithm, which is a prominent tool for solving optimization problems in signal and image processing. This algorithm belongs to the class of proximal methods and puts in a unifying framework many traditional optimization schemes. In particular, the FB algorithm is instrumental for solving nonsmooth optimization problems which are encountered in sparse estimation or compressed sensing. A higher mathematical view of this algorithm can also be given through modern fixed point theory, making it possible to address sophisticated variational problems. Finally, it is shown that this algorithm is also closely related to feedforward neural networks. This link brings insight into the development of more robust and more explainable neural architectures.https://cassyni-user-files-prod.s3.amazonaws.com/9vNjGbZAuYH6geScntp2CN https://cassyni.com/slides/outline/4fJ1CwqCNeC73oLJQsG7yX https://cassyni.com/events/4fJ1CwqCNeC73oLJQsG7yX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/ViPbyUvNEV3hb74kzVgMzn https://cassyni.com/events/4fJ1CwqCNeC73oLJQsG7yX?videoPreview=1 Large language models and future of sciencenohttps://cassyni.com/events/4fJ1CwqCNeC73oLJQsG7yX?videoPreview=12024-01-22T16:00:00+00:003230.04DeSci FoundationIn this talk, we will explore the transformative potential of large language models (LLMs) such as ChatGPT in reshaping scientific inquiry and communication through several vignettes. First, we will discuss how LLM can provide informative feedback to improve scientific manuscripts. Then we will show how to use LLMs to organize biomedical images to make it easier for clinicians and researchers to retrieve relevant information. Finally we will investigate using LLMs for outreach and education. https://cassyni-user-files-prod.s3.amazonaws.com/ViPbyUvNEV3hb74kzVgMzn https://cassyni.com/events/NSfNzBdyaV46DMrJgR1Bhf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VGzGPmNUPivPZwsJvWFtTp https://cassyni.com/slides/outline/C524uCY4xWVwYNrmNk7rPX https://cassyni.com/events/C524uCY4xWVwYNrmNk7rPX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RTzLGKuayUmCGiQ76arw1p https://cassyni.com/events/C524uCY4xWVwYNrmNk7rPX?videoPreview=1 Why can't we predict traits from the environment?nohttps://cassyni.com/events/C524uCY4xWVwYNrmNk7rPX?videoPreview=12023-10-19T16:30:00+00:002730.48New PhytologistPlant functional traits are powerful ecological tools, but the relationships between plant traits and climate (or environmental variables more broadly) are often remarkably weak. This presents a paradox: Plant traits govern plant interactions with their environment, but the environment does not strongly predict the traits of plants living there. Unpacking this paradox requires differentiating the mechanisms of trait variation and potential confounds of trait–environment relationships at different evolutionary and ecological scales ranging from within species to among communities. It also necessitates a more integrated understanding of physiological and evolutionary equifinality among many traits and plant strategies, and challenges us to understand how supposedly ‘functional’ traits integrate into a whole-organism phenotype in ways that may be largely orthogonal to environmental tolerances.https://cassyni-user-files-prod.s3.amazonaws.com/RTzLGKuayUmCGiQ76arw1p https://cassyni.com/slides/outline/NwJz2sHW1wc9D8PCGrHyxy https://cassyni.com/events/NwJz2sHW1wc9D8PCGrHyxy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6RDeYAiF79NiC2iTMYriWr https://cassyni.com/events/NwJz2sHW1wc9D8PCGrHyxy?videoPreview=1 Ordinary, basic, and elliptic hypergeometric series - weighted enumeration and convolutionsnohttps://cassyni.com/events/NwJz2sHW1wc9D8PCGrHyxy?videoPreview=12023-11-22T17:00:00+00:004098.52The Journal of Algebraic CombinatoricsWe give a brief survey on the three-level hierarchy of hypergeometric series: ordinary (or rational) hypergeometric series, basic (or trigonometric, or q-) hypergeometric series, and, on the top level, elliptic hypergeometric series. The three different types of hypergeometric series satisfy a number of well known identities. Arguably the most fundamental identity for single series is the 10-V-9 summation formula (discovered by Frenkel and Turaev in 1997). This powerful elliptic hypergeometric series identity includes many of the other classical summations as special or limiting cases, including the well-known q-Chu-Vandermonde summation, an identity which can be easily interpreted combinatorially and corresponds to a convolution of q-binomial coefficients. We give a similar combinatorial interpretation for the 10-V-9 summation, now as a convolution of elliptic binomial coefficients. This is achieved by a weighted enumeration of lattice paths in a suitable lattice path model where we choose the weights to be specific elliptic functions. The weighted lattice path interpretation corresponds to a formulation entirely in algebraic terms; we describe an algebra of so called "elliptic commuting variables" in which the elliptic binomial coefficients appear as the normal form coefficients of a binomial. While our focus in this talk is on identities for basic and elliptic hypergeometric series (and part of our motivation for giving this talk is to make the area of elliptic hypergeometric series better known, in particular to researchers working in algebraic combinatorics), other suitable choices of the weights in our convolutions of weighted binomial coefficients yield convolutions of symmetric functions.https://cassyni-user-files-prod.s3.amazonaws.com/6RDeYAiF79NiC2iTMYriWr https://cassyni.com/slides/outline/HWBLXMAjBuX4pG8xfwJByX https://cassyni.com/events/HWBLXMAjBuX4pG8xfwJByX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DkwftPjP6RDb5xvsSip2kv https://cassyni.com/events/HWBLXMAjBuX4pG8xfwJByX?videoPreview=1 Introducing Transformative Plant Biotechnology: Finding drugs in the garden: Harnessing plant metabolic diversity for therapeutic applicationsnohttps://cassyni.com/events/HWBLXMAjBuX4pG8xfwJByX?videoPreview=12023-09-20T14:15:00+00:001773.04The New Phytologist FoundationPlants produce a wealth of natural products. The vast majority of the natural product diversity encoded by plant genomes remains as yet untapped. The explosion in plant genome sequence data, coupled with affordable DNA synthesis and new DNA assembly technologies, now offer unprecedented opportunities to harness the full breadth of plant natural product diversity and generate novel molecules in foreign hosts using synthetic biology approaches. The recent discovery that genes for the synthesis of different kinds of natural products are organised in biosynthetic gene clusters in plant genomes opens up opportunities for mining for new pathways and chemistries. This advance, in combination with powerful new transient plant expression technology, is enabling the development of rational strategies to produce known and new-to-nature chemicals tailored for food, health and industrial applications. This presentation will focus on our work on developing a translational synthetic biology pipeline for rapid preparative access to plant natural products and novel analogs using synthetic biology approaches, focusing in particular on the elucidation of the pathway for saponin vaccine adjuvants from the Chilean soapbark tree. Our results enable for the first time the production of soapbark vaccine adjuvants in a heterologous expression system and open the way for new routes to access and engineer natural and new-to-nature immunostimulants.https://cassyni-user-files-prod.s3.amazonaws.com/DkwftPjP6RDb5xvsSip2kv https://cassyni.com/events/VrPSgSLrAMMvhwNmeHrv7f/seminar/qa https://cassyni.com/slides/outline/VrPSgSLrAMMvhwNmeHrv7f https://cassyni.com/events/VrPSgSLrAMMvhwNmeHrv7f/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7ur6rqJZAKoe4VRpYNfg8n https://cassyni.com/events/VrPSgSLrAMMvhwNmeHrv7f?videoPreview=1 Flight testing of active flutter control technology on a conventional configuration UASnohttps://cassyni.com/events/VrPSgSLrAMMvhwNmeHrv7f?videoPreview=12024-01-17T16:00:00+00:003046.36Department of AeronauticsThe talk will discuss the aircraft design, instrumentation and flight testing considerations leading to the successful flutter controller tests and aeroservoelastic model validation flight test campaign within the EU H2020 project FliPASED, marking the first conventional configuration UAV flying beyond the open-loop flutter speed in May 2023 at DLR’s Cochstedt flight test center. Along with the theoretical control design results the team also explored the effects of sensor selection, model order reduction and custom actuator development and placement to achieve the most suitable demonstrator flight envelope to conduct dangerous test involving pushing the flutter boundary. The project advanced the state-of-art in several areas, including aeroelastic modelling, flight testing, control design and implementation as well as operational modal analysis and model order reduction. All the flight test data generated within the 28 flights of the project are available open-source to benefit the flight testing and aeroelasticity research community.https://cassyni-user-files-prod.s3.amazonaws.com/7ur6rqJZAKoe4VRpYNfg8n https://cassyni.com/slides/outline/87rreMskrCzWuC6VGCUFRF https://cassyni.com/events/87rreMskrCzWuC6VGCUFRF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3fDe6zP9MnkPni83KaeA6a https://cassyni.com/events/87rreMskrCzWuC6VGCUFRF?videoPreview=1 FuturePub London — The AI Editionnohttps://cassyni.com/events/87rreMskrCzWuC6VGCUFRF?videoPreview=12023-10-30T19:00:00+00:004237.24#FuturePub is back in London for our third event of 2023 :) And this time it's at the amazing Bounce Farringdon - a ping pong club and so much more! We're hosting this FuturePub to kick off some interesting conversations around AI and research - the good, the bad and the ugly - ahead of the UK Government's AI Safety Summit taking place in Bletchley Park on 1st and 2nd November. That's a pretty closed event, but luckily the AI Fringe, a programme of events that we are proud to be featuring in, is taking place across London and the UK all week, with a range of exciting events that everyone can get involved with. Our final speaker line up is now confirmed. You can register to attend [here](https://www.digital-science.com/events/futurepub-london-ai-tech-for-good/), and recordings of the lightning talks will be uploaded after the event.https://cassyni-user-files-prod.s3.amazonaws.com/3fDe6zP9MnkPni83KaeA6a https://cassyni.com/slides/outline/2gjD8qkz2AuSWKrFfHUTRo https://cassyni.com/events/2gjD8qkz2AuSWKrFfHUTRo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Padu55fP6tQQ9EZv3xRYGn https://cassyni.com/events/2gjD8qkz2AuSWKrFfHUTRo?videoPreview=1 Heat equations beyond Fourier: from heat waves to thermal metamaterialsnohttps://cassyni.com/events/2gjD8qkz2AuSWKrFfHUTRo?videoPreview=12023-12-11T12:00:00+00:004902.04Physics ReportsIn the past few decades, numerous heat conduction models extending beyond Fourier's have been developed to account for large gradients, fast phenomena, wave propagation, and heterogeneous material structures typical of biological systems, superlattices, and thermal metamaterials. Navigating through these models has become challenging due to their varying thermodynamic backgrounds and potential compatibility issues. Furthermore, recent discoveries in the field of non-Fourier heat conduction have complicated the interpretation and utilization of specific non-Fourier heat equations, especially when designing materials for the new generation of thermal metamaterials. The situation is further compounded by the existence of numerous modeling strategies in the literature, each offering different interpretations of even the same heat equation. This complexity makes it increasingly difficult to gain a comprehensive understanding of this research field. Therefore, this review aims to facilitate the navigation of advanced heat equations beyond Fourier by discussing their properties and potential practical applications in the context of experiments. We begin with the simplest models and their fundamental principles, progressing toward more complex, coupled phenomena, such as ballistic heat conduction. We do not delve into the often intricate technical details of each thermodynamic framework or aim to compare each approach from a methodological perspective. Instead, we focus on reviewing models primarily from the Rational Extended Thermodynamics, Extended Irreversible Thermodynamics, and Non-Equilibrium Thermodynamics with Internal Variables frameworks. Additionally, we discuss relevant models from kinetic theory, fractional derivatives, thermomass, and phase lag approaches. We provide background information on these models to highlight their origins, any limitations they may have, and the corresponding stability conditions, if applicable. Furthermore, as the field of non-Fourier heat conduction has become quite segmented, this paper also seeks to establish a common foundation, promoting a comprehensive mutual understanding of the fundamentals of each model and the phenomena to which they can be applied.https://cassyni-user-files-prod.s3.amazonaws.com/Padu55fP6tQQ9EZv3xRYGn https://cassyni.com/slides/outline/CZhJ4WhUoKymMqrHArEpZj https://cassyni.com/events/CZhJ4WhUoKymMqrHArEpZj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Q4hRiYVJ5mWHPpgdvX62Px https://cassyni.com/events/CZhJ4WhUoKymMqrHArEpZj?videoPreview=1 Approach and separation of bundles of quantized vorticitynohttps://cassyni.com/events/CZhJ4WhUoKymMqrHArEpZj?videoPreview=12023-06-14T14:30:00+00:002574.28Leeds Institute for Fluid DynamicsIn the quasiclassical regime of quantum turbulence, it has long been hypothesized that there exist coherent vortical structures, made up of bundles of quantized vortices. More recently, there has been significant experimental evidence that points to their presence. Here, we perform a quantitative study of the reconnection of bundles of quantized vorticity and show that the approach and separation of bundles during a reconnection is consistent with the symmetric δ ∼ t^1/2 scaling which is consistent with studies of individual quantized vortex reconnection and classical vortex reconnections. We also examined the phenomena of “bridge” structures that form between the vortex bundles during the reconnection process and have also been observed during the reconnection of classical vortices. We study their persistence and suggest that their dissipation is driven by vortex-vortex interactions within the bridge itself.https://cassyni-user-files-prod.s3.amazonaws.com/Q4hRiYVJ5mWHPpgdvX62Px https://cassyni.com/slides/outline/LxkBxmDHfUKUfeu9XGWKRF https://cassyni.com/events/LxkBxmDHfUKUfeu9XGWKRF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KcrzJPfa8eXMfiGQRaZZDQ https://cassyni.com/events/LxkBxmDHfUKUfeu9XGWKRF?videoPreview=1 Approaching the solar dynamo from unusual anglesnohttps://cassyni.com/events/LxkBxmDHfUKUfeu9XGWKRF?videoPreview=12021-11-04T12:00:00+00:003643.24Leeds Institute for Fluid DynamicsNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/KcrzJPfa8eXMfiGQRaZZDQ https://cassyni.com/events/PRzDCBSurm5y2bNi4xQx9B/seminar/qa https://cassyni.com/slides/outline/PRzDCBSurm5y2bNi4xQx9B https://cassyni.com/events/PRzDCBSurm5y2bNi4xQx9B/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6VpoaMRV84bzHKrqf1722J https://cassyni.com/events/PRzDCBSurm5y2bNi4xQx9B?videoPreview=1 Safe Prescribing on Dialysis: Latest update on Directly-acting Oral Anticoagulantsnohttps://cassyni.com/events/PRzDCBSurm5y2bNi4xQx9B?videoPreview=12024-03-14T09:30:00+00:002360.04Imperial College Renal and Transplant CentreThe evidence for the use of Directly-acting Oral Anticoagulants (DOACs) to prevent stroke in patients with non-valvular AF is compelling for patients with normal and modestly impaired renal function. Patients with more advanced Chronic Kidney Disease and treated with Dialysis have a high prevalence of AF and risk factors for stroke based on conventional measures. They have unconventional vascular disease. Until very recently the evidence base for patients with CKD4/5 and Dialysis has remained confined to cohort observational studies which are confounded. Prescribing practice for anticoagulants is inferred rather than proven and carries risk. There is new hope! Notably since 2021, there have been the first ever randomised control trials published in Haemodialysis. Similar trials have not been done in Peritoneal Dialysis. We will learn: 1] The existing evidence for anticoagulant treatment 2] The benefit and harm from treatment 3] What DOACs add This is an opportunity for delegates of the Dialysis Academy to re-examine their anticoagulant practice where the risk of bleeding is substantial and the benefits uncertainhttps://cassyni-user-files-prod.s3.amazonaws.com/6VpoaMRV84bzHKrqf1722J https://cassyni.com/events/KySysPvEnZDKzu59RJ2zcM/seminar/qa https://cassyni.com/slides/outline/KySysPvEnZDKzu59RJ2zcM https://cassyni.com/events/KySysPvEnZDKzu59RJ2zcM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Whgp4rDR7Q9rFrtm6U9gog https://cassyni.com/events/KySysPvEnZDKzu59RJ2zcM?videoPreview=1 Radiotherapy and immunotherapy combinations for cancer treatment: past, present and futurenohttps://cassyni.com/events/KySysPvEnZDKzu59RJ2zcM?videoPreview=12024-01-25T16:00:00+00:005609.08Research Seminars by Springer NatureWhile several preclinical studies have outlined the potential of radiotherapy and immunotherapy combinations for cancer treatment, their clinical implementation remains a challenge, with limited clinical benefit reported so far. In this webinar, our panelists will discuss recent developments and persisting challenges in this exciting field from a clinical and translational perspective. The webinar will be hosted by [Nature Communications](https://www.nature.com/ncomms/) editors in collaborations with ImmunoRad. Nature Communications and ImmunoRad declare no (financial and non-) competing interests in the organization of this event.https://cassyni-user-files-prod.s3.amazonaws.com/Whgp4rDR7Q9rFrtm6U9gog https://cassyni.com/events/WqiGtS9nSdPoXAuB2qGgZB/seminar/qa https://cassyni.com/slides/outline/WqiGtS9nSdPoXAuB2qGgZB https://cassyni.com/events/WqiGtS9nSdPoXAuB2qGgZB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VbECiK1V87udVdykx1VW5c https://cassyni.com/events/WqiGtS9nSdPoXAuB2qGgZB?videoPreview=1 Association of flooding exposure with cause-specific mortality in North Carolina, United Statesnohttps://cassyni.com/events/WqiGtS9nSdPoXAuB2qGgZB?videoPreview=12024-01-18T13:00:00+00:001842.56Nature WaterFlooding could have a significant impact on human health, but its association with different causes of mortality remains unclear. Here we employed a two-stage time-series design, utilizing data from 446,807 deaths that occurred during 2015 to 2019, across 98 counties in North Carolina (NC), United States (US). We first estimated the associations between flooding exposure and cause-specific mortality at the county level, and then aggregated those county-level estimates to determine the overall associations at the state level. Compared to the non-flooding days, the relative risk of deaths associated with flooding exposure was 1.039 (95%CI, 0.998-1.083) (one-day lag), 1.046 (95%CI, 1.003-1.092) (one-day lag), and 1.322 (95%CI, 1.166-1.501) (two-day lag) for total, non-accidental, and accidental mortality, respectively. Flooding exposure was also associated with mortality risks for cardiovascular disease, respiratory disease, and mental disorders. Older adults aged 65 years old and above experienced a significantly higher risk increase in accidental mortality compared to the rest of the population (those aged 0-64 years old). More total deaths were attributable to Non-Flash Flood compared to Flash Flood, and more total deaths were attributable to Multiple-day Flood compared to One-day Flood. Compared to One-day Flood, Multiple-day Flood was associated with higher relative risks in all six causes of death (total, non-accidental, accidental, cardiovascular, respiratory, and mental disorders). If this association is causal, the estimated flood-attributable mortality would be 201 deaths per year, where Multiple-day Flood contributed 69%, and One-day Flood contributed 31% of attributable deaths. Our study may contribute to a better understanding of flooding-related health impacts.https://cassyni-user-files-prod.s3.amazonaws.com/VbECiK1V87udVdykx1VW5c https://cassyni.com/events/RQadNv31cbJj8JewRvGtZj/seminar/qa https://cassyni.com/events/RQadNv31cbJj8JewRvGtZj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GmzbQQddnCFmP36YKP2qpr https://cassyni.com/slides/outline/69J4aFoYVjhrMicSWcgasX https://cassyni.com/events/69J4aFoYVjhrMicSWcgasX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/79P6Jn3tmyn67bChu7eoTU https://cassyni.com/events/69J4aFoYVjhrMicSWcgasX?videoPreview=1 Distinct MUNC lncRNA structural domains regulate transcription of different promyogenic factorsnohttps://cassyni.com/events/69J4aFoYVjhrMicSWcgasX?videoPreview=12023-10-19T14:00:00+00:003281.04Center for Cancer TrainingLong non-coding RNAs (lncRNA) are a type of RNA that is not translated into protein. Many lncRNAs have been discovered using high-throughput sequencing data; however, it is unclear what fraction of them is functional and what structural properties affect their phenotype. One of the lncRNAs important for skeletal muscle differentiation is MUNC acting in cis as an enhancer RNA for the Myod1 gene and in trans by recruiting the cohesin complex. Here, experimental probing of the RNA structure revealed that MUNC contains multiple structural domains not detected by prediction algorithms in the absence of experimental information. We show that these specific and structurally distinct domains are required for induction of muscle-related genes, for binding genomic sites and gene expression regulation, and for binding the cohesin complex. Our study reveals unexpectedly complex, structure-driven functions for the MUNC and emphasizes the importance of experimentally determined structures for understanding structure-function relationships in lncRNAs.https://cassyni-user-files-prod.s3.amazonaws.com/79P6Jn3tmyn67bChu7eoTU https://cassyni.com/events/Cp27RLJ7AApxcu6W8yb9P/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Hp2FcRZ9yoWhS8pKKNAypa https://cassyni.com/events/8cY5og3Ah2ULif614JbDbT/seminar/qa https://cassyni.com/slides/outline/8cY5og3Ah2ULif614JbDbT https://cassyni.com/events/8cY5og3Ah2ULif614JbDbT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WaXQogJY131sWqLCtBkHT4 https://cassyni.com/events/8cY5og3Ah2ULif614JbDbT?videoPreview=1 Lattice engineered nanoscale Fe0 for selective reductionsnohttps://cassyni.com/events/8cY5og3Ah2ULif614JbDbT?videoPreview=12024-01-25T13:00:00+00:002431.28Nature WaterAchieving rapid and highly selective chemical reductions using Fe0 nanomaterials for water treatment remains challenging. Impregnating lattice Ni and S into crystalline Fe0 with controllable lattice strain and S speciation provides a strategy to overcome the reactivity–selectivity–stability trade-off. Chemoselective dehalogenation and hydrogenation at a remarkable activity (up to 956-fold higher than for unmodified Fe0) outcompete H2 evolution for >90% electrons from lattice-doped Fe0, which also offers high stability in air and water. This talk will demonstrate how to tune the local microenvironment and physicochemical properties of Fe0 via lattice engineering, toward selective reductions of contaminants in water.https://cassyni-user-files-prod.s3.amazonaws.com/WaXQogJY131sWqLCtBkHT4 https://cassyni.com/slides/outline/G2G9Vvk3GtnBDEcU2BSx1T https://cassyni.com/events/G2G9Vvk3GtnBDEcU2BSx1T/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3Gotv2N4PGG6bpkXDr42Zt https://cassyni.com/events/G2G9Vvk3GtnBDEcU2BSx1T?videoPreview=1 Multi-term fractional integro-differential equations in power growth function spacesnohttps://cassyni.com/events/G2G9Vvk3GtnBDEcU2BSx1T?videoPreview=12023-01-12T15:00:00+00:003369.04Journal of Mathematical SciencesIn this joint talk with Drs. Dinh Thanh Duc and Tran Dinh Phung we will introduce a space of average power growth functions on ℝ+, its characterization, and its applications in studying multi-term Caputo fractional integro-differential equations, multi-term Riemann-Liouville fractional integro-differential equations, and time fractional partial differential equations.https://cassyni-user-files-prod.s3.amazonaws.com/3Gotv2N4PGG6bpkXDr42Zt https://cassyni.com/events/3g43LqZvJSwKKZNf3ptDsK/seminar/qa https://cassyni.com/slides/outline/3g43LqZvJSwKKZNf3ptDsK https://cassyni.com/events/3g43LqZvJSwKKZNf3ptDsK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UmSS3Sdz3xviSbN5td6FYz https://cassyni.com/events/3g43LqZvJSwKKZNf3ptDsK?videoPreview=1 Interdisciplinary approaches to understanding language endangermentnohttps://cassyni.com/events/3g43LqZvJSwKKZNf3ptDsK?videoPreview=12024-09-11T09:00:00+00:001964.04Cambridge PrismsLanguage diversity is under threat, with between a third to a half of the world’s spoken languages considered endangered, and predicted rates of loss equivalent to one language per month for the rest of the century. This seminar focuses on interdisciplinary research adapting methods developed in biology to study patterns and causes of language endangerment and loss. While the causes of language endangerment are different to those for species, their analyses must overcome similar challenges, including detecting significant patterns over stochastic processes, and avoiding confounding correlations due to phylogenetic non-independence and spatial autocorrelation. I will briefly discuss three case studies: using population modelling to study language shift over generations; adapting the genotype concept to identify risk factors for language loss in a small community; and application of macroecological approaches to describing global patterns and correlates of language endangerment, including prediction of future language loss. https://cassyni-user-files-prod.s3.amazonaws.com/UmSS3Sdz3xviSbN5td6FYz https://cassyni.com/slides/outline/Ab8VzQdGSrh6pNNERGTA21 https://cassyni.com/events/Ab8VzQdGSrh6pNNERGTA21/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XJT9kTMQnwVAhmmuUQ8w3k https://cassyni.com/events/Ab8VzQdGSrh6pNNERGTA21?videoPreview=1 Rapid detection of mutations in CSF‑cfTNA with the Genexus Integrated Sequencernohttps://cassyni.com/events/Ab8VzQdGSrh6pNNERGTA21?videoPreview=12024-01-29T21:00:00+00:001542.08Journal of Neuro-OncologyJoin the Journal of Neuro-Oncology's Editor-in-Chief, Dr. Jason Sheehan, and Associate Editor, Dr. Randy D'Amico, for a conversation with Dr. Yoshua Esquenazi Levy and Dr. Leomar Y. Ballester from the University of Texas MD Anderson Cancer Center to discuss their latest publication on the rapid detection of mutations in CSF‑cfTNA with the Genexus Integrated Sequencer.https://cassyni-user-files-prod.s3.amazonaws.com/XJT9kTMQnwVAhmmuUQ8w3k https://cassyni.com/events/B5n736GntKF9p8u81hjxHK/seminar/qa https://cassyni.com/slides/outline/B5n736GntKF9p8u81hjxHK https://cassyni.com/events/B5n736GntKF9p8u81hjxHK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FKwbthdNsUvnZ5SPhE4Juk https://cassyni.com/events/B5n736GntKF9p8u81hjxHK?videoPreview=1 Community assembly of the human piercing microbiomenohttps://cassyni.com/events/B5n736GntKF9p8u81hjxHK?videoPreview=12024-02-01T15:00:00+00:003102.76Royal Society PublishingPredicting how biological communities respond to disturbance requires understanding the forces that govern their assembly. We propose using human skin piercings as a model system for studying community assembly after rapid environmental change. Local skin sterilization provides a ‘clean slate’ within the novel ecological niche created by the piercing. Stochastic assembly processes can dominate skin microbiomes due to the influence of environmental exposure on local dispersal, but deterministic processes might play a greater role within occluded skin piercings if piercing habitats impose strong selection pressures on colonizing species. Here we explore the human ear-piercing microbiome and demonstrate that community assembly is predominantly stochastic but becomes significantly more deterministic with time, producing increasingly diverse and ecologically complex communities. We also observed changes in two dominant and medically relevant antagonists (*Cutibacterium acnes* and *Staphylococcus epidermidis*), consistent with competitive exclusion induced by a transition from sebaceous to moist environments. By exploiting this common yet uniquely human practice, we show that skin piercings are not just culturally significant but also represent ecosystem engineering on the human body. The novel habitats and communities that skin piercings produce may provide general insights into biological responses to environmental disturbances with implications for both ecosystem and human health.https://cassyni-user-files-prod.s3.amazonaws.com/FKwbthdNsUvnZ5SPhE4Juk https://cassyni.com/events/6dyHjZxxLZBgBBbxJioZ3j/abstract https://cassyni-user-files-prod.s3.amazonaws.com/V1bpG9QeAESExENmoLFAWi https://cassyni.com/slides/outline/hVFGjVhwyeen5tcJF6ZKb https://cassyni.com/events/hVFGjVhwyeen5tcJF6ZKb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WXanqJovA8upLFT5kWff3t https://cassyni.com/events/hVFGjVhwyeen5tcJF6ZKb?videoPreview=1 The Air-Conditioning Paradox: Protecting Vulnerable Populations from Extreme Heatnohttps://cassyni.com/events/hVFGjVhwyeen5tcJF6ZKb?videoPreview=12023-11-08T15:00:00+00:002996.36Data-Centric Engineering JournalOver 50% of people worldwide live in urban areas, and by 2050 this fraction is expected to increase to 70%. Meanwhile, extreme heat events are increasing in frequency and intensity, posing a human health risk for urbanites. As extreme heat is the leading cause of weather-related fatalities, research that helps identify the populations that are most vulnerable to extreme heat is urgently needed. While access to air conditioning (AC) is one of the most important adaptive technologies to protect people from heat, AC usage requires vast amounts of electricity that can exacerbate warming, both locally and globally, creating a policy paradox. We also have a very limited understanding of trends in AC access and usage, making it difficult to reach the most populations most vulnerable to extreme heat. This presentation will describe a body of work dedicated to building a more quantitative understanding of heat vulnerabilities across the Southern California region via novel methods of estimating AC penetration rates and anthropogenic heat.https://cassyni-user-files-prod.s3.amazonaws.com/WXanqJovA8upLFT5kWff3t https://cassyni.com/events/E3hMRpfpvRVWfm8RGbfHTj/seminar/qa https://cassyni.com/slides/outline/E3hMRpfpvRVWfm8RGbfHTj https://cassyni.com/events/E3hMRpfpvRVWfm8RGbfHTj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2kEVucd6biBLaMGfqmgT5x https://cassyni.com/events/E3hMRpfpvRVWfm8RGbfHTj?videoPreview=1 Springer Nature’s Research Communities: Connecting the Stories Behind the Researchnohttps://cassyni.com/events/E3hMRpfpvRVWfm8RGbfHTj?videoPreview=12024-03-26T16:00:00+00:001695.44Topics at the heart of our communityOur 42 Research Communities encompass the natural, applied and humanitarian disciplines, and boast a membership of over 42,000 researchers and science-interested readers. Join our next Spotlight On… event to learn how these platforms will provide our Editors and Authors alike with greater opportunities to connect and collaborate with your networkhttps://cassyni-user-files-prod.s3.amazonaws.com/2kEVucd6biBLaMGfqmgT5x https://cassyni.com/slides/outline/BaTLCQSCj8iydbtdoorvTX https://cassyni.com/events/BaTLCQSCj8iydbtdoorvTX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5CeiSgs7sbaQs4novthgW2 https://cassyni.com/events/BaTLCQSCj8iydbtdoorvTX?videoPreview=1 Sizing Up Skull Allometrynohttps://cassyni.com/events/BaTLCQSCj8iydbtdoorvTX?videoPreview=12024-03-21T10:00:00+00:001149.4Royal Society PublishingIn this seminar, I discuss how the overall size of an animal influences the function of its skull, and the role this can play in the diversity of skull shapes seen in mammals. I outline recent developments in our understanding of allometry (size-related changes) in skull function, and emphasise that size is an underestimated driver of functional adaptation. Because size variation is often extracted from shape data to examine adaptive patterns, some of this size-correlated variation relating to skull function might frequently be missed. In our latest publication with *Biology Letters*, we analysed the skulls and teeth of 370 Australian rock-wallabies (Macropodidae: *Petrogale*), representing all 17 species. We show that allometry across species can be correlated positively, or negatively, with allometry within species at different parts of the skull, and that these different regions can be related to the biomechanics of feeding. We suggest that allometric patterns receive more scrutiny regarding their role in skull function.https://cassyni-user-files-prod.s3.amazonaws.com/5CeiSgs7sbaQs4novthgW2 https://cassyni.com/events/97DJxzCaXqxVGfR5G7xHjb/seminar/qa https://cassyni.com/slides/outline/97DJxzCaXqxVGfR5G7xHjb https://cassyni.com/events/97DJxzCaXqxVGfR5G7xHjb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/F6yWHDWuLE5EigbBxxBQLv https://cassyni.com/events/97DJxzCaXqxVGfR5G7xHjb?videoPreview=1 Peaks, Valleys, and Blur: Optimization and Uncertainty Quantificationnohttps://cassyni.com/events/97DJxzCaXqxVGfR5G7xHjb?videoPreview=12024-05-09T12:30:00+00:002200.04Nonlinear Dynamics, an International Journal of Nonlinear Dynamics and Chaos in Engineering SystemsI describe the integration of parameter continuation techniques with variational calculus and covariance analysis for purposes of design optimization and uncertainty quantification along families of periodic and quasi-periodic orbits of nonlinear dynamical systems, as well as solutions to more general classes of multi-segment boundary-value problems, including those coupled through time delays. This integration has been realized in the Matlab-based software package COCO by supporting the automated construction of adjoint contributions to the corresponding Karush-Kuhn-Tucker conditions. I describe the general software design principles and illustrate the methodology on toy problems that capture the full complexity of the approach while also allowing for analytical and/or simulation-based validation.https://cassyni-user-files-prod.s3.amazonaws.com/F6yWHDWuLE5EigbBxxBQLv https://cassyni.com/slides/outline/VNGfoiVANkQb8VyDgc1j4R https://cassyni.com/events/VNGfoiVANkQb8VyDgc1j4R/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HwR9w6h5Hvib7MqjDsAv8E https://cassyni.com/events/VNGfoiVANkQb8VyDgc1j4R?videoPreview=1 MPS-VQE: A variational quantum computational chemistry simulator with matrix product statesnohttps://cassyni.com/events/VNGfoiVANkQb8VyDgc1j4R?videoPreview=12024-07-01T13:00:00+00:002260.88Computer Physics CommunicationsQuantum computing is attracting more and more attention in material and biological science. In the noisy intermediate-scale quantum (NISQ) computing era, the variational quantum eigensolver (VQE) is expected as an effective method to solve quantum chemistry problems which has potential quantum advantage. Classically simulating quantum algorithms plays a critical role in algorithmic development and the validation of noisy quantum devices before large-scale, fully fault-tolerant quantum computers are developed. However, most existing simulators are based on the state vector or density matrix representation of the quantum state which is faced with the memory bottleneck due to the exponential growth of memory requirement as the number of qubits increases. In this work, we present a VQE simulator based on the matrix product states (MPS) method from quantum many-body physics, and a detailed study of our MPS-VQE simulator in quantum chemistry applications. The memory requirement of MPS-VQE grows only polynomially and we demonstrate that accurate results can be obtained despite the truncation of the smallest singular values during the algorithm. A distributed parallelization scheme is also presented for massively parallel computer systems, and different implementations of the parallelization scheme based on the Julia language are benchmarked which demonstrate the efficiency and scalability of our method. Our method could open a new avenue towards large-scale classical simulation of quantum computational chemistry.https://cassyni-user-files-prod.s3.amazonaws.com/HwR9w6h5Hvib7MqjDsAv8E https://cassyni.com/events/Pw92JCNPYiKC16PRfymq73/seminar/qa https://cassyni.com/slides/outline/Pw92JCNPYiKC16PRfymq73 https://cassyni.com/events/Pw92JCNPYiKC16PRfymq73/abstract https://cassyni-user-files-prod.s3.amazonaws.com/mqqW2TDvoJWa2F87XLzZ4 https://cassyni.com/events/Pw92JCNPYiKC16PRfymq73?videoPreview=1 Improving Menstrual Health throughout the Reproductive Life Coursenohttps://cassyni.com/events/Pw92JCNPYiKC16PRfymq73?videoPreview=12024-06-21T15:00:00+00:003363.2Women's HealthThe natural biological occurrence of menstruation occurs among half of the world’s population, yet the experience of those who menstruate is not commonly discussed. Challenges related to menstruation include stigma and shame around menstruation, access to menstrual health services, the invisibility of menstrual pain, management of menstrual flow, lack of menstrual education, the menstrual experiences of trans and non-binary people, period poverty, and early menopause among other issues. Current conversations and education around menstruation are inadequate and do not address the root cause of menstrual marginalization: shame and stigma that is deeply ingrained in our shared cultural experience from myriad sources. This Special Collection seeks to address this entrenched stigma by highlighting research conducted in a variety of disciplines, among diverse groups in a variety of cultural traditions, and throughout the reproductive life course. https://cassyni-user-files-prod.s3.amazonaws.com/mqqW2TDvoJWa2F87XLzZ4 https://cassyni.com/events/RujSUvxVJYXx6off2wdmXb/seminar/qa https://cassyni.com/slides/outline/RujSUvxVJYXx6off2wdmXb https://cassyni.com/events/RujSUvxVJYXx6off2wdmXb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3jXhzyv9UdHVF76fwk9mtr https://cassyni.com/events/RujSUvxVJYXx6off2wdmXb?videoPreview=1 Spotlight On…Research Integrity: Current Challenges and How to Protect Your Journalnohttps://cassyni.com/events/RujSUvxVJYXx6off2wdmXb?videoPreview=12024-05-30T14:00:00+00:003606.04Topics at the heart of our communityResearch integrity and publication ethics are about trust. How can you be confident that the research articles you are reading and citing are reliable? What can be done to protect the integrity of the publication record? Join Tim Kersjes, Head of Research Integrity, Resolutions, as he presents case studies of best practices, and explores the latest trends, tools, and challenges pertaining to issues of research integrity. Discover how the Springer Nature Research Integrity Group is supporting both our Editors and the wider research community in publishing robust and reliable research.https://cassyni-user-files-prod.s3.amazonaws.com/3jXhzyv9UdHVF76fwk9mtr https://cassyni.com/events/5AW4YDnSsKGgxpDNkpiRe5/seminar/qa https://cassyni.com/slides/outline/5AW4YDnSsKGgxpDNkpiRe5 https://cassyni.com/events/5AW4YDnSsKGgxpDNkpiRe5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QCTuTw6rjcS8if5Kd97xGE https://cassyni.com/events/5AW4YDnSsKGgxpDNkpiRe5?videoPreview=1 SYNTHESIS/SYNLETT Best Paper Awards 2023nohttps://cassyni.com/events/5AW4YDnSsKGgxpDNkpiRe5?videoPreview=12024-06-27T07:00:00+00:005305.32Thieme GroupThieme Chemistry and the editors of SYNTHESIS and SYNLETT present the "[SYNTHESIS/SYNLETT Best Paper Awards](https://www.thieme.de/de/thieme-chemistry/journals-synthesis-synlett-best-paper-awards-72162.htm)" to honor outstanding research in chemical synthesis. In this Thieme Cheminar, our speakers will present their research related to their award-winning articles which can be read [here](https://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-1941-8680) and [here](https://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-1912-3216). Our line-up: - Takaaki Sato (Japan) – “Total Synthesis and Anti-inflammatory Activity of Stemoamide-Type Alkaloids” - Santanu Mukherjee (India) – “Breaking Symmetry: Reaction Development & Application to Complex Targets” Don't miss this opportunity to gain insights from leading scientists and learn about the latest advances in synthetic chemistry. RSVP above to save your spot!https://cassyni-user-files-prod.s3.amazonaws.com/QCTuTw6rjcS8if5Kd97xGE https://cassyni.com/events/7dk5me254c3BKkgwJWd4N1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KTKcP8BvcpgWiBwwKxmqDQ https://cassyni.com/slides/outline/4BCrSrVPzQAYJ4PNerF6qB https://cassyni.com/events/4BCrSrVPzQAYJ4PNerF6qB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LALNeB6wGVD2dofjWnVHaN https://cassyni.com/events/4BCrSrVPzQAYJ4PNerF6qB?videoPreview=1 Mesh Generation and ongoing Developmentsnohttps://cassyni.com/events/4BCrSrVPzQAYJ4PNerF6qB?videoPreview=12024-06-13T10:00:00+00:006149.36Nektar++ Development TeamThis session presents ongoing development on mesh generation and other application of spectral/hp element within Nektar++ framework and comprises the following talks 1. Implementation of the Parareal Algorithm in the Nektar++ Spectral/hp Element Framework with Applications to Linear and Non-Linear Problems 2. NekMesh: High-Order Mesh Generation and Adaptation with NekMesh 3. Locomotion of microparticles close to wallhttps://cassyni-user-files-prod.s3.amazonaws.com/LALNeB6wGVD2dofjWnVHaN https://cassyni.com/slides/outline/EYpYRD5RD1nxpZgWfxBzWh https://cassyni.com/events/EYpYRD5RD1nxpZgWfxBzWh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/V6c914WPgrqRPExh5kZRaN https://cassyni.com/events/EYpYRD5RD1nxpZgWfxBzWh?videoPreview=1 The Experimental Double Pendulum on a Cart: A Benchmark System for Chaos, Learning, and Controlnohttps://cassyni.com/events/EYpYRD5RD1nxpZgWfxBzWh?videoPreview=12022-08-12T14:00:00+00:00367.84Brunton LabIn this video, Dr. Kaheman describes the experimental multi-arm pendulum as a rich benchmark system for data-driven modeling and control. https://cassyni-user-files-prod.s3.amazonaws.com/V6c914WPgrqRPExh5kZRaN https://cassyni.com/slides/outline/F3U9TtiweUM1pLDQGPUnn1 https://cassyni.com/events/F3U9TtiweUM1pLDQGPUnn1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QjSDUAQABurtobJvRXgAH4 https://cassyni.com/events/F3U9TtiweUM1pLDQGPUnn1?videoPreview=1 Symmetry’s made to be broken: Learning how to break symmetry with symmetry-preserving neural networksnohttps://cassyni.com/events/F3U9TtiweUM1pLDQGPUnn1?videoPreview=12023-01-06T14:00:00+00:003854.08AI Institute in Dynamic SystemsSymmetry-preserving (equivariant) neural networks are extremely data-efficient and generalize well when applied to diverse domains (e.g. computer vision and atomic systems). But, are there circumstances where equivariance is too strict or otherwise undesirable? In this talk, I’ll discuss how symmetry-preserving neural networks can learn symmetry-breaking information in order to fit a dataset that may have missing information unbeknownst to the researcher. Furthermore, due to the mathematical guarantees of equivariant neural networks, these learned parameters are guaranteed to be minimally symmetry breaking. I’ll describe network architectures that can learn these symmetry-breaking parameters in two distinct settings: 1) symmetry-breaking parameters are learned for an entire dataset to capture global asymmetries in the data and 2) symmetry-breaking parameters are predicted in an equivariant manner for individual examples. Finally, I’ll demonstrate these networks on several prototypical examples and apply them to predicting structural distortions of crystalline materials.https://cassyni-user-files-prod.s3.amazonaws.com/QjSDUAQABurtobJvRXgAH4 https://cassyni.com/slides/outline/9cLVxNcApSFwRTyAfUUznZ https://cassyni.com/events/9cLVxNcApSFwRTyAfUUznZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TT13DvTYbvuS12S3DzB4Gn https://cassyni.com/events/9cLVxNcApSFwRTyAfUUznZ?videoPreview=1 Handling messy time series with large latent-variable modelsnohttps://cassyni.com/events/9cLVxNcApSFwRTyAfUUznZ?videoPreview=12020-11-13T14:00:00+00:003690.52AI Institute in Dynamic SystemsMuch real-world data is sampled at irregular intervals, but most time series models require regularly-sampled data. Continuous-time models address this problem, but until now only deterministic models (based on ordinary differential equations) or linear-Gaussian models were efficiently trainable with millions of parameters. We construct a scalable algorithm for computing gradients through samples from stochastic differential equations (SDEs), and for gradient-based stochastic variational inference in function space, all with the use of adaptive black-box SDE solvers. This allows us to fit a new family of richly-parametrized distributions over time series, in which neural networks can parametrize both dynamics and likelihoods. We demonstrate these latent SDEs on motion capture data, and provide an open-source PyTorch library for fitting large SDE models.https://cassyni-user-files-prod.s3.amazonaws.com/TT13DvTYbvuS12S3DzB4Gn https://cassyni.com/slides/outline/MxaEE6JBCF2XTcuNvPzAZK https://cassyni.com/events/MxaEE6JBCF2XTcuNvPzAZK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8a4CXbHGq3TpDbbNfFCymp https://cassyni.com/events/MxaEE6JBCF2XTcuNvPzAZK?videoPreview=1 Using Combinatorial Transformation to produce Valuable Metabolites in Nicotiana tabacumnohttps://cassyni.com/events/MxaEE6JBCF2XTcuNvPzAZK?videoPreview=12024-06-07T13:30:00+00:00876.2New Phytologist Foundation Cannabinoids such as cannabidiol (CBD) are important secondary metabolites produced mainly on the flowering parts of Cannabis sativa plants, which are known to have a multitude of human therapeutic values. Cannabis also produced over 120 different cannabinoids, with many therapeutics yet to be uncovered. However, cannabis cannot produce standardized amounts of cannabinoids. Different environmental factors such as light and water are known to affect both the amount and type of cannabinoids produced. My project overcomes this issue by introducing the cannabinoid metabolic pathway into a model plant species, *Nicotiana tabacum*, using combinatorial transformation. This involves introducing the set of genes required for metabolite production in a single bombardment, with independent plant lines being generated from subsequent regeneration. Results from this set of experiments show cannabinoid-producing transgenic tobacco lines, which is yet to be described in the literature. This study demonstrates the potential for *Nicotiana tabacum* to be used as a vessel for standardized secondary metabolite production.https://cassyni-user-files-prod.s3.amazonaws.com/8a4CXbHGq3TpDbbNfFCymp https://cassyni.com/events/KVLCzg4YzxFzRTfbTcBoZ7/seminar/qa https://cassyni.com/slides/outline/KVLCzg4YzxFzRTfbTcBoZ7 https://cassyni.com/events/KVLCzg4YzxFzRTfbTcBoZ7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4wMvEypfxyMKskPBTJKzJa https://cassyni.com/events/KVLCzg4YzxFzRTfbTcBoZ7?videoPreview=1 Aerodynamics of a dart-shaped projectile at low Reynolds number, An assessment of effective slope as a parameter for turbulent drag prediction over multi-scaled roughnessnohttps://cassyni.com/events/KVLCzg4YzxFzRTfbTcBoZ7?videoPreview=12024-10-08T14:00:00+00:002973.68Experiments in FluidsA sports dart pierces the dartboard because it possesses a remarkable aerodynamic property of ‘self-correcting’ its attitude in flight. This property arises from its aerodynamic design with a long heavy Barrel and large cruciform wings known as flights. We characterize the aerodynamics of dart-shaped projectiles at typical flight Reynolds numbers between 14500 and 20500 using wind tunnel experiments and numerical simulations. Force measurement tests from wind tunnel experiments yield the lift, drag, and pitching moment coefficients over a range of angles of attack; the experimental estimates are in quantitative agreement with those obtained from numerical simulations. Examining the surface pressure distribution, streamlines, and wall shear–stress distribution, along with the skin friction lines obtained from numerical simulations, reveals that the aerodynamics of the dart is governed by an interaction between the Barrel vortex (BV) shed by the cone–cylinder body and the wing leading edge vortex (WLV) over the horizontal flights influenced by solid impediment offered by the vertical flights. Smoke flow visualization images corroborate the vortex–vortex and vortex–wall interactions over the flights found in the numerical simulations. A complex interplay of vortex structures is observed, which depends on the angle of attack. The WLV develops an elliptic instability while exhibiting a partial merger with the Barrel vortex in the presence of secondary vorticity generated by the walls amidst the rapid weakening of the WLV. We conclude that the role of aerodynamics is largely pitch stabilization by means of aerodynamic moment and the normal force generation. The streamwise effective slope ($ES_x$), which is the mean absolute streamwise gradient of the roughness, is considered to be a key parameter in predicting the drag penalty of rough-wall turbulent boundary-layers. However, many real-world rough surfaces are multi-scaled. For such surfaces, $ES_x$ can be unbounded and its value can be dominated by scales of the topography that are invisible to the flow. To illustrate this, a campaign of drag balance measurements was conducted with a set of machined surfaces. A baseline surface is prepared with fine machining parameters. By coarsening the machining precision, artefacts called ‘scallops’ are introduced which increases the ‘measured’ $ES_x$ without changing other geometrical statistics. The drag of the ‘scalloped’ surfaces is higher than the baseline surface, with the relative drag increase scaling with the viscous scaled scallop height, but only when their height exceeds $2\sim3$ times the viscous length scale. Further, the drag of one of the ‘scalloped’ cases, even when the scallop height is $\mathcal{O}(10)$ viscous units, is seen to be much lower ($\sim 28$%) than a case with matched $ES_x$, but where the $ES_x$ results from larger scale features. These findings confirm that for multi-scaled surfaces, $ES_x$ may be a misleading topographical metric for drag (or $k_s$) prediction and one must consider which scales contribute to the average slope of a surface.https://cassyni-user-files-prod.s3.amazonaws.com/4wMvEypfxyMKskPBTJKzJa https://cassyni.com/slides/outline/QRpFTWXoPXo1pZNwU5toHF https://cassyni.com/events/QRpFTWXoPXo1pZNwU5toHF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/A3hAQiZ6iSwV2EZWDsPNLE https://cassyni.com/events/QRpFTWXoPXo1pZNwU5toHF?videoPreview=1 Panel: The future of plant sciencenohttps://cassyni.com/events/QRpFTWXoPXo1pZNwU5toHF?videoPreview=12024-06-08T18:30:00+00:003152.0New Phytologist Foundation No abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/A3hAQiZ6iSwV2EZWDsPNLE https://cassyni.com/events/XqYK9mEfyQ6rK8uQRxkXhF/seminar/qa https://cassyni.com/slides/outline/XqYK9mEfyQ6rK8uQRxkXhF https://cassyni.com/events/XqYK9mEfyQ6rK8uQRxkXhF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5umE9VWaYEoFRyrSDaTtzi https://cassyni.com/events/XqYK9mEfyQ6rK8uQRxkXhF?videoPreview=1 Beyond MHDnohttps://cassyni.com/events/XqYK9mEfyQ6rK8uQRxkXhF?videoPreview=12024-09-16T14:00:00+00:003555.0Journal of Computational PhysicsThe MHD equations have served plasma physicists, space physicists and astrophysicists very well for the past several decades. Even so, one comes to the realization that the MHD equations are only an approximation that applies to systems where the collision rate between charged particles is fast enough to rapidly restore isotropy in the pressure tensor. For many systems involving collisionless plasmas, this assumption of the isotropy of the pressure tensor is invalid. In such situations, the Chew Goldberger and Low equations take over. They are based on a double adiabatic approximation and allow the pressure parallel to the field lines to differ from the pressure perpendicular to the field lines. While the CGL equations are well-formed, they have resisted numerical solution for a very long time. The reason is that if these equations are taken by themselves, they could potentially give rise to an unbounded increase in pressure anisotropy in certain circumstances. This unbounded increase in anisotropy can eventually result in a loss of hyperbolicity and a consequent code crash. Real world systems, like the solar wind, show that there are limits to the pressure anisotropy. Therefore, to make sense of the CGL equations, and their physical import, one has to understand the plasma physics effects, such as the mirror instability and firehose instability, which restore pressure isotropy at a microphysical level. Folding in these physical effects also results in numerical challenges that have to be overcome. In this talk we show how the CGL equations can be made numerically tractable by a deft combination of physical reasoning and advanced numerical methods. Preliminary applications will also be presented. https://cassyni-user-files-prod.s3.amazonaws.com/5umE9VWaYEoFRyrSDaTtzi https://cassyni.com/events/Su4GgvmRapZpv3C4RV3Xy7/seminar/qa https://cassyni.com/slides/outline/Su4GgvmRapZpv3C4RV3Xy7 https://cassyni.com/events/Su4GgvmRapZpv3C4RV3Xy7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Qh7WWckPB4zEPeNS8gJUop https://cassyni.com/events/Su4GgvmRapZpv3C4RV3Xy7?videoPreview=1 Dual Catalysisnohttps://cassyni.com/events/Su4GgvmRapZpv3C4RV3Xy7?videoPreview=12024-08-22T07:00:00+00:007228.32Thieme GroupDual catalysis is a powerful strategy for developing new organic reactions that used to be challenging to achieve by traditional methods. Whether through relay catalysis or synergistic catalysis, it does not only facilitate complicated multiple bond formations but also enriches the toolbox for constructing novel molecules. In this Thieme Cheminar, chaired by SYNTHESIS Editor Jung Min Joo, our speakers will present their latest research on dual catalysis. Speaker line-up: • Weiwei Zi (Nankai University) - “Synergistic Catalysis Enabled Stereodivergent Csp3–Csp3 Coupling Reactions” • Philip Wai Hong Chan (Monash University) - “Recent adventures at the intersection of Brønsted acid, gold and photoredox catalysis” • Chun-Jiang Wang (Wuhan University) - “Synergistic Catalysis with Azomethine Ylides” This Thieme Cheminar is of particular interest to organic chemistry students, graduates, and researchers in industry and academia. Sign up now to save your spot! https://cassyni-user-files-prod.s3.amazonaws.com/Qh7WWckPB4zEPeNS8gJUop https://cassyni.com/events/SQQfeF7u9N1mvGfAq3kjho/seminar/qa https://cassyni.com/slides/outline/SQQfeF7u9N1mvGfAq3kjho https://cassyni.com/events/SQQfeF7u9N1mvGfAq3kjho/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4qzKMX85TuXkgYmu1JhguC https://cassyni.com/events/SQQfeF7u9N1mvGfAq3kjho?videoPreview=1 Engaging with Research from Chinanohttps://cassyni.com/events/SQQfeF7u9N1mvGfAq3kjho?videoPreview=12024-07-31T14:00:00+00:003774.2Topics at the heart of our communityRitu Dhand will be in conversation with special guests Enda Bergin (Editorial Director, Nature Communications), and Professor Bhekie Mamba (Editor-In-Chief, npj Clean Water), sharing experiences and insights into fostering connections with the research community in China, and how the impact of their efforts benefited their journals. This event serves as an expansion on our previous topic in November 2023: 'High Impact Research from China'.https://cassyni-user-files-prod.s3.amazonaws.com/4qzKMX85TuXkgYmu1JhguC https://cassyni.com/events/D4uMPnejJ14MGrjMWoh8EH/seminar/qa https://cassyni.com/slides/outline/D4uMPnejJ14MGrjMWoh8EH https://cassyni.com/events/D4uMPnejJ14MGrjMWoh8EH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9quxF7h93LWC3SQw6Gkan2 https://cassyni.com/events/D4uMPnejJ14MGrjMWoh8EH?videoPreview=1 Active control of very-large-scale motions using wall deformationnohttps://cassyni.com/events/D4uMPnejJ14MGrjMWoh8EH?videoPreview=12025-01-14T15:00:00+00:003244.16Experiments in FluidsI will discuss the activities of my research group on the experimental development and understanding of the effects of active surface deformation on a turbulent boundary layer, with particular emphasis on its impact on very large-scale motions (VLSMs). My talk will cover the development of an actuator driven by a voice coil for on-demand surface deformation, along with a real-time particle image velocimetry (PIV) system for flow sensing. Our preliminary experiments have evaluated the ability of active surface deformation to control ejections and sweeps in a simple periodic flow and have characterized the effects of periodic actuation in both laminar and turbulent boundary layers. The insights gained from these experiments have been used to implement a feed-forward system to control VLSMs in a turbulent boundary layer. The results demonstrate how active surface deformation can influence the strength of VLSMs and provide guidelines for the future development of active deformable surfaces in practical applications.https://cassyni-user-files-prod.s3.amazonaws.com/9quxF7h93LWC3SQw6Gkan2 https://cassyni.com/events/C5c9JRMgR5xCc6uMQqDoRP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FvLKaLF6gz4tqCY4Ghc99Q https://cassyni.com/events/Nwu4S677UX4QGrRnJwPvzq/seminar/qa https://cassyni.com/slides/outline/Nwu4S677UX4QGrRnJwPvzq https://cassyni.com/events/Nwu4S677UX4QGrRnJwPvzq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CtkWD8LxtcULpiUKda7b2W https://cassyni.com/events/Nwu4S677UX4QGrRnJwPvzq?videoPreview=1 What do science journalists look for in a study when deciding whether to write about it?nohttps://cassyni.com/events/Nwu4S677UX4QGrRnJwPvzq?videoPreview=12024-08-22T14:00:00+00:002812.88CassyniScience journalists consider a number of factors when deciding whether to write about a study or not. My experience is that most scientists don't understand how the media works, what they should do to build bridges with journalists, and how media coverage can help them in their career. In this talk, I'll aim to cover all those talking points as well as giving some hints and tips on what scientists can actively do to attract more journalists to their papers. https://cassyni-user-files-prod.s3.amazonaws.com/CtkWD8LxtcULpiUKda7b2W https://cassyni.com/events/VryX5fATcvpBmfRMgNxs9X/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UPqeHa2jRKNRuWmDL7NXSv https://cassyni.com/slides/outline/QvVUcphDEMHANZi1fuFsRP https://cassyni.com/events/QvVUcphDEMHANZi1fuFsRP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HCsNd3PGkV6MEzbCuRTQGn https://cassyni.com/events/QvVUcphDEMHANZi1fuFsRP?videoPreview=1 Quantum Electrodynamics in Electrolytic Environment and Applications to Molecular Junction Electronicsnohttps://cassyni.com/events/QvVUcphDEMHANZi1fuFsRP?videoPreview=12025-01-14T13:00:00+00:003231.68Electrochimica ActaThe quantum rate theory provides a framework to understand electron-transfer reactions by correlating the electron-transfer rate constant ($\nu$) with the quantum capacitance ($C_q$) and the molecular conductance ($G$). This theory, which is rooted in relativistic quantum electrodynamics, predicts a fundamental frequency $\nu = E/h$ for electron-transfer reactions, where $E$ is the energy associated with the density of states $C_q/e^2$. This work demonstrates the applicability of the quantum rate theory to the intermolecular charge transfer of push-pull heterocyclic compounds assembled over conducting electrodes. Remarkably, the observed differences between molecular junction electronics formed by push-pull molecules and the electrodynamics of electrochemical reactions on redox-active modified electrodes can be attributed solely to the adiabatic setting of the quantum conductance in push-pull molecular junctions. The electrolyte field-effect screening environment plays a crucial role in modulating the resonant quantum conductance dynamics of the molecule-bridge-electrode structure. In this context, the intermolecular electrodynamics within the frontier molecular orbital of push-pull heterocyclic molecules adhere to relativistic quantum mechanics, consistent with the predictions of the quantum rate theory.https://cassyni-user-files-prod.s3.amazonaws.com/HCsNd3PGkV6MEzbCuRTQGn https://cassyni.com/slides/outline/88Sw3ahNJnSmxv95JHaCT7 https://cassyni.com/events/88Sw3ahNJnSmxv95JHaCT7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/H8ooWEEaGqTvvRniviBHLJ https://cassyni.com/events/88Sw3ahNJnSmxv95JHaCT7?videoPreview=1 Longitudinal disease-associated gut microbiome differences in infants with early food allergic manifestationsnohttps://cassyni.com/events/88Sw3ahNJnSmxv95JHaCT7?videoPreview=12021-11-09T20:00:00+00:00796.76Microbiome Virtual International Forum Complex interactions between the gut microbiome and immune cells in infancy are thought to be part of the pathogenesis for the marked rise in pediatric allergic diseases, particularly food allergies. Food protein-induced allergic proctocolitis (FPIAP) is commonly the earliest recognized non-IgE-mediated food allergy in infancy and is associated with atopic dermatitis and subsequent IgE-mediated food allergy later in childhood. Yet, a large prospective longitudinal study of the microbiome of infants with FPIAP (including samples prior to symptom onset) has not been done. Here we analyzed 954 longitudinal samples from 160 infants in a nested case-control study (81 who developed FPIAP, and 79 matched controls) from 1 week to 1 year of age by 16S rRNA ribosomal gene sequencing as part of the Gastrointestinal Microbiome and Allergic Proctocolitis (GMAP) Study. We confirmed that vaginally delivered infants had a greater abundance of Bacteroides, infants who received any breast milk had a greater abundance of Bifidobacterium, and that overall bacterial richness rose over the first year. We found key differences in the microbiome of infants with FPIAP, most strongly a higher abundance of a genus of Enterobacteriaceae and a lower abundance of a family of Clostridiales during the symptomatic period, as well as other key taxonomic differences across symptom states including prior to symptom onset. This study contributes to the larger body of literature examining structural development of the early life gut microbiome and provides a foundation for more mechanistic investigation into the pathogenesis and microbial effects on FPIAP and subsequent food allergic diseases in childhood.https://cassyni-user-files-prod.s3.amazonaws.com/H8ooWEEaGqTvvRniviBHLJ https://cassyni.com/events/2hKHY4abUkMha3tqhNaQTf/seminar/qa https://cassyni.com/slides/outline/2hKHY4abUkMha3tqhNaQTf https://cassyni.com/events/2hKHY4abUkMha3tqhNaQTf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/P9zai1oxTWej793iq6S6wx https://cassyni.com/events/2hKHY4abUkMha3tqhNaQTf?videoPreview=1 YADE - An extensible framework for the interactive simulation of multiscale, multiphase, and multiphysics particulate systemsnohttps://cassyni.com/events/2hKHY4abUkMha3tqhNaQTf?videoPreview=12024-11-19T14:00:00+00:003607.48Computer Physics CommunicationsThis seminar presents the key elements of YADE, an extensible open-source framework for dynamic simulations. During the past 19 years, YADE has evolved from “Yet Another Dynamic Engine” to a versatile multiscale and multiphysics solver, counting a large, active, and growing community of users and developers. The computationally intense parts of the source code are written in C++, using flexible object models that allow for easy implementation of new features. The source code is wrapped in Python, equipping the software with an interactive kernel used for rapid and concise scene construction, simulation control, post-processing, and debugging. The project, including documentation and examples, is hosted on [https://yade-dem.org](https://yade-dem.org), while the source code is freely available on GitLab. Over the last decade, YADE has expanded in terms of capabilities thanks to the contribution of many developers from different fields of expertise, including soil and rock mechanics, chemical engineering, physics, bulk material handling, and mineral processing. The rapid growth of YADE can be attributed to (1) the careful and robust design of the framework core, (2) a continuous integration pipeline with fully embedded thorough tests which are executed upon each merge request, ensuring stable compilation for various operating systems, and (3) user-friendliness, facilitated by the Python interface, detailed documentation, and rigorous user support. This seminar reviews the main features of YADE, highlighting its versatility in terms of applications, its flexibility in terms of code development, as well as recent improvements in terms of computational efficiency.https://cassyni-user-files-prod.s3.amazonaws.com/P9zai1oxTWej793iq6S6wx https://cassyni.com/slides/outline/3BxtakE7vCukZpRjHosCiy https://cassyni.com/events/3BxtakE7vCukZpRjHosCiy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/C5JUMNRsnhRyc3qe5W3pU6 https://cassyni.com/events/3BxtakE7vCukZpRjHosCiy?videoPreview=1 Illuminating the black box: developing new genetic systems for genetically intractable microbiome speciesnohttps://cassyni.com/events/3BxtakE7vCukZpRjHosCiy?videoPreview=12022-04-12T13:00:00+00:00668.0Microbiome Virtual International Forum With the recent explosion of next-generation sequencing and OMICS studies of human microbiome communities, a surprisingly broad diversity of diseases have been found to correlate with mucosal dysbiosis. Another consequence of such studies is an exponential increase in the number of uncharacterized and understudied microbes identified as potential drivers of mucosal health and disease. Thus, there is an impending challenge looming on the horizon to reveal the molecular basis for these observations. To meet this challenge, many newly identified microbes will require the development of new genetic systems useful for interrogating experimental models. Our laboratory has devoted a significant effort to improve the genetic tractability of a variety of important understudied microbiome species, especially those that have been traditionally considered as “genetically intractable”. Here, we will discuss a recently developed genetic system for one such pathobiont species, Parvimonas micra. Our preferred approach to develop new genetic systems begins with identifying and exploiting endogenous natural competence abilities (i.e. energy-dependent exogenous DNA uptake). Accordingly, we identified a natural competence ability in P. micra, which allowed us to employ cloning-independent methodologies to construct a variety of targeted genetic mutations directly within low-passage clinical isolates. In addition, we successfully developed a luciferase-based reporter system, a theophylline-inducible gene expression system, and a Mariner transposon mutagenesis system for Tn-seq studies of P. micra. While natural competence is widely believed to be a specialized ability of a small number of prokaryotes, we have reason to believe that it is likely to be quite common among bacteria. As such, natural competence could provide a clear path to investigate the genetics of the numerous novel organisms identified from microbiome studies.https://cassyni-user-files-prod.s3.amazonaws.com/C5JUMNRsnhRyc3qe5W3pU6 https://cassyni.com/slides/outline/CaHNTjX6FuS2RZtsCwLmbb https://cassyni.com/events/CaHNTjX6FuS2RZtsCwLmbb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Tzsjirrv7PAQmGVfBm4WGn https://cassyni.com/events/CaHNTjX6FuS2RZtsCwLmbb?videoPreview=1 Pervasive selective sweeps across human gut microbiomesnohttps://cassyni.com/events/CaHNTjX6FuS2RZtsCwLmbb?videoPreview=12024-02-27T13:00:00+00:00662.04Microbiome Virtual International Forum The human gut microbiome is composed of a highly diverse consortia of species which are continually evolving within and across hosts. The ability to identify adaptations common to many host gut microbiomes would not only reveal shared selection pressures across hosts, but also key drivers of functional differentiation of the microbiome that may affect community structure and host traits. However, to date there has not been a systematic scan for adaptations that have spread across host microbiomes. Here, we develop a novel selection scan statistic, named the integrated linkage disequilibrium score (iLDS), that can detect the spread of adaptive haplotypes across host microbiomes via migration and horizontal gene transfer. Specifically, iLDS leverages signals of hitchhiking of deleterious variants with the beneficial variant, a common feature of adaptive evolution. We find that iLDS is capable of detecting simulated and known cases of selection, and moreover is robust to potential confounders that can also elevate LD. Application of the statistic to ∼20 common commensal gut species from a large cohort of healthy, Western adults reveals pervasive spread of selected alleles across human microbiomes mediated by horizontal gene transfer. Among the candidate selective sweeps recovered by iLDS is an enrichment for genes involved in the metabolism of maltodextrin, a synthetic starch that has recently become a widespread component of Western diets. In summary, we demonstrate that selective sweeps across host microbiomes are a common feature of the evolution of the human gut microbiome. Link to OA paper: https://www.biorxiv.org/content/10.1101/2023.12.22.573162v1https://cassyni-user-files-prod.s3.amazonaws.com/Tzsjirrv7PAQmGVfBm4WGn https://cassyni.com/slides/outline/PSaHbQGXKLYE6KRJ73WuB3 https://cassyni.com/events/PSaHbQGXKLYE6KRJ73WuB3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FtzS67WZMfc1o4mQi67bvv https://cassyni.com/events/PSaHbQGXKLYE6KRJ73WuB3?videoPreview=1 Minimizing Bias in Microbiome Researchnohttps://cassyni.com/events/PSaHbQGXKLYE6KRJ73WuB3?videoPreview=12023-09-19T11:00:00+00:0065.28Microbiome Virtual International Forum No abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/FtzS67WZMfc1o4mQi67bvv https://cassyni.com/slides/outline/LyLGMz2u83mjjNwjZMcGT7 https://cassyni.com/events/LyLGMz2u83mjjNwjZMcGT7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HdvzVceAZRmP6peztDQUpv https://cassyni.com/events/LyLGMz2u83mjjNwjZMcGT7?videoPreview=1 Maternal smoking during pregnancy increases the risk of gut microbiome-associated childhood overweight and obesitynohttps://cassyni.com/events/LyLGMz2u83mjjNwjZMcGT7?videoPreview=12024-04-17T10:00:00+00:0060.68Microbiome Virtual International Forum Childhood obesity is linked to maternal smoking during pregnancy. Gut microbiota may partially mediate this association and could be potential targets for intervention; however, its role is understudied. We included 1,592 infants from the Canadian Healthy Infants Longitudinal Development Cohort. Data on environmental exposure and lifestyle factors were collected prenatally and throughout the first three years. Weight outcomes were measured at one and three years of age. Stool samples collected at 3 and 12 months were analyzed by sequencing the V4 region of 16S rRNA to profile microbial compositions and magnetic resonance spectroscopy to quantify the metabolites. We showed that quitting smoking during pregnancy did not lower the risk of offspring being overweight. However, exclusive breastfeeding until the third month of age may alleviate these risks. We also reported that maternal smoking during pregnancy significantly increased Firmicutes abundance and diversity. We further revealed that Firmicutes diversity mediates the elevated risk of childhood overweight and obesity linked to maternal prenatal smoking. This effect possibly occurs through excessive microbial butyrate production. These findings add to the evidence that women should quit smoking before their pregnancies to prevent microbiome-mediated childhood overweight and obesity risk, and indicate the potential obesogenic role of excessive butyrate production in early life. Link to OA paper: https://www.tandfonline.com/doi/full/10.1080/19490976.2024.2323234https://cassyni-user-files-prod.s3.amazonaws.com/HdvzVceAZRmP6peztDQUpv https://cassyni.com/slides/outline/Kz34GcjrF8fb4d7jTP8weD https://cassyni.com/events/Kz34GcjrF8fb4d7jTP8weD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AqLzN78Rriw1ewVWVL1CrA https://cassyni.com/events/Kz34GcjrF8fb4d7jTP8weD?videoPreview=1 Development of early life gut resistome and mobilome across gestational ages and microbiota-modifying treatmentsnohttps://cassyni.com/events/Kz34GcjrF8fb4d7jTP8weD?videoPreview=12023-11-14T14:00:00+00:00736.0Microbiome Virtual International Forum Background: Gestational age (GA) and associated level of gastrointestinal tract maturation are major factors driving the initial gut microbiota composition in preterm infants. Besides, compared to term infants, premature infants often receive antibiotics to treat infections and probiotics to restore optimal gut microbiota. How GA, antibiotics, and probiotics modulate the microbiota’s core characteristics, gut resistome and mobilome, remains nascent. Methods: We analysed metagenomic data from a longitudinal observational study in six Norwegian neonatal intensive care units to describe the bacterial microbiota of infants of varying GA and receiving different treatments. The cohort consisted of probiotic-supplemented and antibiotic-exposed extremely preterm infants (n = 29), antibiotic-exposed very preterm (n = 25), antibiotic-unexposed very preterm (n = 8), and antibiotic-unexposed full-term (n = 10) infants. The stool samples were collected on days of life 7, 28, 120, and 365, and DNA extraction was followed by shotgun metagenome sequencing and bioinformatical analysis. Findings: The top predictors of microbiota maturation were hospitalisation length and GA. Probiotic administration rendered the gut microbiota and resistome of extremely preterm infants more alike to term infants on day 7 and ameliorated GA-driven loss of microbiota interconnectivity and stability. GA, hospitalisation, and both microbiota-modifying treatments (antibiotics and probiotics) contributed to an elevated carriage of mobile genetic elements in preterm infants compared to term controls. Finally, Escherichia coli was associated with the highest number of antibiotic-resistance genes, followed by Klebsiella pneumoniae and Klebsiella aerogenes. Interpretation: Prolonged hospitalisation, antibiotics, and probiotic intervention contribute to dynamic alterations in resistome and mobilome, gut microbiota characteristics relevant to infection risk. Link to OA paper: https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00178-0/fulltexthttps://cassyni-user-files-prod.s3.amazonaws.com/AqLzN78Rriw1ewVWVL1CrA https://cassyni.com/slides/outline/WMekEyKsTkJ1b8QsUV5qKj https://cassyni.com/events/WMekEyKsTkJ1b8QsUV5qKj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JNYJaTQvyvZ8NLABDmPRjC https://cassyni.com/events/WMekEyKsTkJ1b8QsUV5qKj?videoPreview=1 Functional and evolutionary characterization of unknown genes from uncultivated taxanohttps://cassyni.com/events/WMekEyKsTkJ1b8QsUV5qKj?videoPreview=12023-03-14T12:00:00+00:00632.04Microbiome Virtual International Forum Over the last decades, the sequencing of environmental DNA by metagenomics has provided the genomes of thousands of uncultivated bacterial and archaeal lineages, revealing an enormous amount of previously unknown genes. Even though recent studies have highlighted the apparent importance of these novel genes, their overall significance is still largely unexplored. Here, we applied a comprehensive comparative genomics approach to identify high-quality novel protein families exclusive from uncultivated species, and characterized them from a functional, ecological and evolutionary point of view. For such a purpose, we computed protein families from a large multi-habitat metagenomic dataset covering 400M genes from 170k genomes spanning the prokaryotic phylogeny. We then applied strict quality and novelty filters to avoid incomplete genes, assembling artifacts, distant homologs and potential pseudogenes. This led us to uncovering 400K high-quality gene families exclusive from uncultivated taxa, twice the number of gene families in reference databases like EggNOG. These high-quality novel gene families are widespread within and across habitats, indicating their ecological value. They also spread out across the microbial phylogeny and are notably overrepresented in recently discovered taxa. Most remarkably, we found that 980 previously neglected protein families can accurately distinguish entire uncultivated phyla, classes and orders, likely representing synapomorphic traits. We inferred the putative functional roles of the high-quality novel gene families by reconstructing their genomic neighborhood and estimating their degree of functional context conservation. 18% of the novel protein families are present in phylogenetically conserved operon regions, in some cases involving key metabolic genes, suggesting they may take part in central microbial processes. In order to facilitate the characterization of novel gene families in relevant genomic contexts, we developed http://novelgenefamilies.compgenomics.org, which allows to browse and visualize the genomic neighbors of any of our novel gene family predictions. Overall, our work provides a global phylogenomic analysis of the largely uncharted repertoire of unique genes from uncultured prokaryotes, serving as a base resource for further investigations on their functional and ecological roles. Link to OA paper: https://www.biorxiv.org/content/10.1101/2022.01.26.477801v1https://cassyni-user-files-prod.s3.amazonaws.com/JNYJaTQvyvZ8NLABDmPRjC https://cassyni.com/slides/outline/WrJMHeyPuCr4atwm4vNdb3 https://cassyni.com/events/WrJMHeyPuCr4atwm4vNdb3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WQb4DN4WMispxJvWtiPHbC https://cassyni.com/events/WrJMHeyPuCr4atwm4vNdb3?videoPreview=1 Control of shock-induced separation using air-jet vortex generatorsnohttps://cassyni.com/events/WrJMHeyPuCr4atwm4vNdb3?videoPreview=12023-11-01T11:00:00+00:002870.04Department of Aeronautics and AstronauticsShock-induced separation leads to highly unsteady flow fields and has strong detrimental effects on the aerodynamic behavior and performance of numerous aerospace-engineering applications. To reduce these effects, separation control is required. A very promising approach is the use of rows of air-jet vortex generators (AJVGs), where small spanwise-inclined jets of air injected into the flow increase the momentum transfer within the boundary layer and thus make it less prone to separation. A large number of parameters influence the control effectiveness of AJVGs, amongst them geometrical parameters, such as the orifice shape, orifice size, and injection-pipe length; flow parameters, including the (steady or forced) injection pressure; and the array arrangement. The talk will provide an overview on the relevant control parameters and their respective influences, also comparing AJVGs with classical mechanical vortex generators. Recent experimental and numerical studies at RWTH Aachen University provide a rich experimental-numerical data set, which we have jointly analyzed and interpreted using statistical methods and modal analysis with dynamic-mode decomposition, amongst other techniques. On the basis of these results, the physical mechanisms and underlying flow dynamics governing the control effect of AJVGs, as well as the observed flow phenomena and control effects, will be presented and discussed. Image credit: [Thomas Stephan (Unsplash)](https://unsplash.com/photos/white-smoke-on-black-background-KLQg7ugoqms).https://cassyni-user-files-prod.s3.amazonaws.com/WQb4DN4WMispxJvWtiPHbC https://cassyni.com/events/RRAhn8rd5AkzC2hXU1Nqbb/seminar/qa https://cassyni.com/slides/outline/RRAhn8rd5AkzC2hXU1Nqbb https://cassyni.com/events/RRAhn8rd5AkzC2hXU1Nqbb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UDgr2evyUQxtvAVgApjxTY https://cassyni.com/events/RRAhn8rd5AkzC2hXU1Nqbb?videoPreview=1 Uniting for a Sustainable Future: Connecting Research, Policy, and Communities for Real-World Impactnohttps://cassyni.com/events/RRAhn8rd5AkzC2hXU1Nqbb?videoPreview=12024-09-24T13:00:00+00:004328.96Springer Nature Sustainable Development Goals ProgrammeFollowing the [UN Summit of the Future](https://www.un.org/en/summit-of-the-future) (September 20-23, 2024), we are honored to welcome Prof. Phoebe Koundouri, a Professor of Economics at Athens University of Economics and Business & Technical University of Denmark; Chair World Council of Environmental Resource Economists Associations; Chair SDSN Global Climate Hub; Co-chair SDSN Europe; Director AE4RIA. Her presentation on SDG 17: Partnerships for the Goals will be chaired by Asja Prohic, Head of Academic Affairs, and Marios Karouzos, Head of Publishing Strategy at Springer Nature, followed by a Q&A session. Abstract: The challenges of multi-stakeholder collaboration and achieving the Sustainable Development Goals (SDGs) have reached a critical juncture. Innovative approaches to cooperation are now more essential than ever, requiring a nuanced understanding of various contexts while ensuring equitable solutions. Prof. Koundouri will draw on her extensive expertise in uniting diverse stakeholders to address global issues through bottom-up and community-based approaches. She will present recent initiatives at the intersection of science and policy and emphasize the importance of measuring their impact. Additionally, Prof. Koundouri will share her insights on the outcomes of the UN Summit of the Future and offer her perspectives on how publishers can contribute to fostering collaboration and addressing inequalities. https://cassyni-user-files-prod.s3.amazonaws.com/UDgr2evyUQxtvAVgApjxTY https://cassyni.com/slides/outline/78u7vYmLoczzdRX1nzsSQ5 https://cassyni.com/events/78u7vYmLoczzdRX1nzsSQ5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4xL4NmcrWmhmXTNSuXxZVG https://cassyni.com/events/78u7vYmLoczzdRX1nzsSQ5?videoPreview=1 A switched control strategy in human balancenohttps://cassyni.com/events/78u7vYmLoczzdRX1nzsSQ5?videoPreview=12025-06-24T13:00:00+00:00522.32NODYSAn inverted pendulum, controlled by a controller switching between optimal energy and decay gain, was proposed to describe the dynamics of humans standing on a harmonically moving platform. It was identified that humans use optimal energy gain to conserve energy and switch to the optimal decay gain to ensure safety. How often optimal decay gain is used is positively related to balance ability, leading to the proposal of new stabilometry parameters that have clear physical meaning, suggesting their potential for assessing early-stage declines in balance stability.https://cassyni-user-files-prod.s3.amazonaws.com/4xL4NmcrWmhmXTNSuXxZVG https://cassyni.com/slides/outline/XLfjC3U4K48to7GrinAjpR https://cassyni.com/events/XLfjC3U4K48to7GrinAjpR/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HvKYj5qVdgJex431AUGqdG https://cassyni.com/events/XLfjC3U4K48to7GrinAjpR?videoPreview=1 Characterizing Bistable Laminate Using Acoustic Emission Datanohttps://cassyni.com/events/XLfjC3U4K48to7GrinAjpR?videoPreview=12025-06-24T10:00:00+00:00579.72NODYSThis study investigates the energy release associated with the snap-through phenomenon in bistable laminates. The potential well characteristics of bistable laminate change with increase in laminate stiffness, leading to higher energy release. An understanding of the laminate stiffness is made from the data generated from acoustic emissions (AE) during the transition between stable states of the laminate. This research compares the potential well characteristics of 2-layer and 4-layer squared bistable laminates using both finite element simulations (ABAQUS) and experimental AE data.https://cassyni-user-files-prod.s3.amazonaws.com/HvKYj5qVdgJex431AUGqdG https://cassyni.com/slides/outline/Tt8VsFwPErGFmQyJ57nnHb https://cassyni.com/events/Tt8VsFwPErGFmQyJ57nnHb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DUWjRZXf5vFpnFov1sUUdL https://cassyni.com/events/Tt8VsFwPErGFmQyJ57nnHb?videoPreview=1 Parametric instabilities of camber morphing wing structure with time-varying stiffnessnohttps://cassyni.com/events/Tt8VsFwPErGFmQyJ57nnHb?videoPreview=12025-06-24T10:00:00+00:00687.12NODYSMorphing wings with variable stiffness structures are a promising concept to improve aircraft performance. However, this can induce parametric instabilities, which have to be studied to avoid failures. A three-degree-of-freedom wing with periodically time-varying stiffness is used for this study. The resulting equation of motion resembles a coupled Mathieu equation with unsteady aerodynamic loads. The parametric instability of the wing is analyzed numerically using the Floquet theory. In this abstract, specifically, the effect of out-of-phase stiffness variation is investigated. It is found that a 180-degree phase difference in the flap stiffness variation reduces the primary parametric instability regions. However, it introduces a new combination instability region.https://cassyni-user-files-prod.s3.amazonaws.com/DUWjRZXf5vFpnFov1sUUdL https://cassyni.com/slides/outline/6eFWss7pNASwdez8CZae8m https://cassyni.com/events/6eFWss7pNASwdez8CZae8m/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FKwkM8CsjPLC3xfavduTAn https://cassyni.com/events/6eFWss7pNASwdez8CZae8m?videoPreview=1 Rub Related Nonlinear Dynamics in a Noisy Non-Smooth Jeffcott Rotor Modelnohttps://cassyni.com/events/6eFWss7pNASwdez8CZae8m?videoPreview=12025-06-24T12:00:00+00:00669.68NODYSStrong and discontinuous nonlinearities arising from friction, contact stiffness, clearances and unbalance excitation and random excitation due to parametric uncertainty make the dynamic analysis of a rotor-stator system complex. This paper presents the dynamics of a nonlinear and non-smooth Jeffcott rotor system. The effects of unbalance force, bearing clearance, rotor-stator impact, tangential rubbing, randomness in rotor parameters due to manufacturing error and assembly deviation are considered in formulating the equations of motion. Both normal impact and tangential rubbing between rotor and stator are modeled respectively as of Hertzian type and dry friction. The parametric uncertainty is modeled by appropriate white noise random processes.https://cassyni-user-files-prod.s3.amazonaws.com/FKwkM8CsjPLC3xfavduTAn https://cassyni.com/slides/outline/F3JQn7ddEJnewU2zYyr8zH https://cassyni.com/events/F3JQn7ddEJnewU2zYyr8zH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Rg1zGXPR7z94d316m9UTa6 https://cassyni.com/events/F3JQn7ddEJnewU2zYyr8zH?videoPreview=1 Core transport predictions of SPARC tokamak plasmas with flux-matched nonlinear gyrokinetic simulationsnohttps://cassyni.com/events/F3JQn7ddEJnewU2zYyr8zH?videoPreview=12025-03-06T16:00:00+00:002962.64Journal of Plasma PhysicsPredicting core gradients in tokamak plasmas using first-principles based models has long been the goal of transport research, but it has largely been intractable due to the large computational expense of nonlinear turbulent simulations. Given this high computational cost, the tokamak transport community has relied on a set of tools that span from empirical methods to quasilinear models of turbulence to scope and study future devices, while only using full nonlinear gyrokinetic simulations as standalone, spot-check validation studies. This talk will present the PORTALS workflow that reduces the computational cost of first-principles, multi-channel, non-linear gyrokinetic profile predictions of the plasma core. Thanks to this, the core of SPARC—a burning-plasma device under construction by Commonwealth Fusion Systems— has been extensively studied and predicted with nonlinear CGYRO. This talk will introduce the need of flux-matched simulations to enable profile predictions, will present the fundamentals of the PORTALS technique and will discuss the findings simulating the core of SPARC, from the impact of edge pressure to impurity effects on turbulence stabilization.https://cassyni-user-files-prod.s3.amazonaws.com/Rg1zGXPR7z94d316m9UTa6 https://cassyni.com/slides/outline/9cAmGbWrQGhaYbnkx4rLzq https://cassyni.com/events/9cAmGbWrQGhaYbnkx4rLzq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UPap2HSoY1BeVgtSUhs5r6 https://cassyni.com/events/9cAmGbWrQGhaYbnkx4rLzq?videoPreview=1 Fusion economics: power density, materials and maintenancenohttps://cassyni.com/events/9cAmGbWrQGhaYbnkx4rLzq?videoPreview=12024-09-12T15:00:00+00:003004.92Journal of Plasma PhysicsA review of prior magnetic d-t fusion power plant (FPP) studies reveals consistent patterns of high fusion power density and effective materials replacement. In order to assess the relative impact of plasma and component design a set of governing relationships that generically solve for optimizing FPP economics are developed, with component usage driven by cumulative neutron damage. Scans of the controlling parameters reveal minimum requirements in power density that are in general agreement with prior studies. Yet the transparent economic model reveals further surprising insights as to the relative importance of power density, neutron tolerance, energy conversion efficiency and financing costs.https://cassyni-user-files-prod.s3.amazonaws.com/UPap2HSoY1BeVgtSUhs5r6 https://cassyni.com/slides/outline/MxQVYKCrn5UAakiyCzMWmb https://cassyni.com/events/MxQVYKCrn5UAakiyCzMWmb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NqHmFbR9bbx8bbTRWVYbhG https://cassyni.com/events/MxQVYKCrn5UAakiyCzMWmb?videoPreview=1 Shear flow generation in magnetised plasmasnohttps://cassyni.com/events/MxQVYKCrn5UAakiyCzMWmb?videoPreview=12023-06-15T15:00:00+00:003128.48Journal of Plasma PhysicsMean shear flows are essential to control confinement in magnetised plasmas for fusion. In absence of external torque, and atomic physics processes, two types of processes are known to drive or damp flows: collisional drag and turbulent flow generation. While the theory of flow generation is well documented in axisymmetric magnetic configurations like tokamaks, it is much less understood when 3D effects are accounted for. In tokamaks, 3D effects may come from magnetic ripple due to the finite number of coils, or magnetic perturbations produced with external coils. In this talk, the physics at play, collisional or turbulent, will first be clarified in a unified framework. Analytical theory is compared to a set of comprehensive simulations based on drift-kinetic or gyrokinetic approaches able to treat both collisions and turbulence on an equal footing, thus allowing an assessment of competing processes. This methodology has recently been applied to understand the improvement of confinement with plasma current. When 3D effects are accounted for, it appears that collisional drag prevails over turbulence beyond a threshold in ripple amplitude that is expected to be reached in ITER. The talk will end with some considerations on the edge-core interplay regarding flow generation.https://cassyni-user-files-prod.s3.amazonaws.com/NqHmFbR9bbx8bbTRWVYbhG https://cassyni.com/slides/outline/QReWmjSUyNEewhCXkgG9VX https://cassyni.com/events/QReWmjSUyNEewhCXkgG9VX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9uHBjoudi2pjSDeLY1jYEa https://cassyni.com/events/QReWmjSUyNEewhCXkgG9VX?videoPreview=1 ST40: Advancing the Physics Basis of Spherical Tokamak Reactorsnohttps://cassyni.com/events/QReWmjSUyNEewhCXkgG9VX?videoPreview=12022-10-27T15:00:00+00:002748.44Journal of Plasma PhysicsST40 is a high field Spherical Tokamak, built and operated by Tokamak Energy, with R geo ≈0.4-0.5m, A≈1.6-1.9, κ<1.7, I p ≈0.4-0.8MA and B T ≈0.8-2.2T. Two co-injected hydrogen neutral beams deliver 0.8MW at 50kV and 0.7MW at 24kV. With deuterium the corresponding figures are 1.0MW/55kV and 0.8MW/24kV, respectively. The vessel walls are conditioned with helium GDC and boronization. Merging-compression start-up is used. The plasmas is mainly limited on the high field side, although some diverted plasmas were obtained. The primary goal for the 2021-2 operations was the attainment of the business objective, T i (0) > 100MK (8.6keV). A central deuterium ion temperature of 9.6keV was obtained together with 𝑛 i (0).𝑇 𝑖 (0).𝜏 E ≈ 6 ± 2 × 10 18 m−3•keV•s. Such high ion temperatures have only previously been achieved in significantly larger devices and never reached in a ST. However, in order to access the high Ti regime, the electron temperature must be high enough that the collisional power transfer from ions to electrons is significantly smaller than the input power density. In the best ST40 shots, T e (0) > 3keV was observed, which is in contrast to the T e (0) <2.4keV in neutral beam heated STs of twice the major radius but with B T <0.8T. The results from ST40 are consistent with the NSTX observation of an approximately linear B T dependence of energy confinement time. A limited TF scan and comparisons between high Ti data at 1.6 and 1.92T, on axis, demonstrate the beneficial effect of high B T . The dominant loss channel is via electrons. The observation of high temperature lends support to the high field ST route to economical, compact fusion reactors.https://cassyni-user-files-prod.s3.amazonaws.com/9uHBjoudi2pjSDeLY1jYEa https://cassyni.com/events/H1vT5UjcPVw9Bf1dCWeX3T/abstract https://cassyni-user-files-prod.s3.amazonaws.com/J1y83vrnKPZDyBbJTbvCAa https://cassyni.com/events/KVAUJtyEanhdYbVBkCZ9mP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LVD9HM6QWgKiL84s1HpptW https://cassyni.com/slides/outline/XqNaTz9MZEYVSGiziZ7suX https://cassyni.com/events/XqNaTz9MZEYVSGiziZ7suX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EgHSjPaEvadwUBw64EaSv2 https://cassyni.com/events/XqNaTz9MZEYVSGiziZ7suX?videoPreview=1 Reconnection-controlled decay of magnetohydrodynamic turbulence and the role of invariantsnohttps://cassyni.com/events/XqNaTz9MZEYVSGiziZ7suX?videoPreview=12021-08-26T15:00:00+00:003482.44Journal of Plasma PhysicsIn this talk, I will describe a new theoretical picture of magnetically dominated, decaying turbulence in the absence of a mean magnetic field. I shall argue that the energy-decay rate of such a system is governed by the reconnection of magnetic structures, and not necessarily by ideal dynamics, as has previously been assumed. I will explain how a prediction for the decay law of magnetic energy can be obtained by assuming reconnection-mediated dynamics that respects the conservation of certain integral invariants, which represent topological constraints satisfied by the reconnecting magnetic field. As is well known, the magnetic helicity is such an invariant for initially helical field configurations, but does not constrain non-helical decay, where the volume-averaged magnetic-helicity density vanishes. For such a decay, I shall propose a new integral invariant, analogous to the Loitsyansky and Saffman invariants of hydrodynamic turbulence, that expresses the conservation of the random [scaling as volume^(1/2)] magnetic helicity contained in any sufficiently large volume. The existence of this `Saffman helicity invariant’ leads to a natural explanation of the inverse-transfer phenomenon reported by previous numerical studies. Finally, I shall describe an application of these results to the decay of primordial magnetic fields in the early Universe.https://cassyni-user-files-prod.s3.amazonaws.com/EgHSjPaEvadwUBw64EaSv2 https://cassyni.com/events/SQEvxU2ajCTR3QUm7e85v5/abstract https://cassyni.com/events/SttY19g7Af1U3B1ei5QtBP/abstract https://cassyni.com/events/5f1Z1krYHyC9uR2UqXCk2Z/abstract https://cassyni.com/slides/outline/C4NkGigghDCE8yAn6yf33s https://cassyni.com/events/C4NkGigghDCE8yAn6yf33s/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4L6E3cqEB2wXKSckiGp36E https://cassyni.com/events/C4NkGigghDCE8yAn6yf33s?videoPreview=1 Analysis of the efficacy of interventional treatment of venous malformations of the footnohttps://cassyni.com/events/C4NkGigghDCE8yAn6yf33s?videoPreview=12025-10-14T09:48:08+00:00560.0Society for Pediatric Interventional Radiology## Introduction Venous malformations (VMs) in the foot often pose a treatment challenge due to their diffuse nature and involvement of nerves, muscles, and joints, often causing pain, swelling, and dysfunction. This study assesses the clinical efficacy, safety, and long-term outcomes of interventional sclerotherapy for the treatment of venous malformations in the foot in children, and to investigate factors influencing treatment efficacy. ## Materials and Methods We retrospectively analysed data from 30 paediatric patients (aged 1-19 years, mean 6.17±4.48 years) treated for foot VMs at our centre from January 2021 to December 2024. Patients underwent ultrasound and/or DSA-guided sclerotherapy, using polydocanol foam, pingyangmycin, tissue adhesive, and spring coils. Lesions were classified according to the Puig’s system. Outcomes included number of treatments, technical success, VM volume reduction, and complications, pain improvement (via visual analogue scale, VAS), and functional recovery. Mean follow-up was 18 months. ## Results Sclerotherapy achieved a 90.0% effectiveness rate (27/30). Each patient underwent 3.37 ± 1.79 (range 1-8) sclerotherapy sessions. Post-treatment, 90.0% showed >50% VM volume reduction and significant swelling improvement; VAS score fell from 6.8 to 1.9 (P<0.001), with foot function improving by 68.3%. All patients experienced swelling (30/30), with bruising (1/30), and blisters (1/30), but no serious complications. VM distance from the skin surface predicted complications (p<0.01). No relapsed occurred, and quality of life improved markedly. ## Discussion Interventional sclerotherapy is an effective and safe treatment for foot venous malformations, offering sustained outcomes and enhanced quality of life.https://cassyni-user-files-prod.s3.amazonaws.com/4L6E3cqEB2wXKSckiGp36E https://cassyni.com/slides/outline/4fbrTsVwocP6f3ziZ7ayvM https://cassyni.com/events/4fbrTsVwocP6f3ziZ7ayvM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/76iqZoZqB7qwyGRC4er1Y2 https://cassyni.com/events/4fbrTsVwocP6f3ziZ7ayvM?videoPreview=1 Mechanisms and Universality in the Subcritical Route to Turbulencenohttps://cassyni.com/events/4fbrTsVwocP6f3ziZ7ayvM?videoPreview=12020-06-12T15:00:00+00:003945.36UK Fluids NetworkRecent years have witnessed a profound change in our understanding of the route to turbulence in wall-bounded shear flows. In start contract to the classical Hopf-Landau picture where turbulence arises through an increase in the temporal complexity of fluid motion, the route to turbulence in subcritical shear flows occurs via spatio-temporal intermittency and falls in the class of non-equilibrium statistical phase transitions known as directed percolation. In this talk, Dwight Barkley focuses on two aspects of the transition problem. The first is physical mechanisms underlying spatio-temporal intermittency in shear flows. The second is the universality in the subcritical route to turbulence.https://cassyni-user-files-prod.s3.amazonaws.com/76iqZoZqB7qwyGRC4er1Y2 https://cassyni.com/events/Lxc5PcdrefgqvxqJ8bCn2y/seminar/qa https://cassyni.com/events/Lxc5PcdrefgqvxqJ8bCn2y/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BUe59CeTWMfgY8esYPcxp6 https://cassyni.com/slides/outline/EYYKGuvZBQXhN6JLn7QuRf https://cassyni.com/events/EYYKGuvZBQXhN6JLn7QuRf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/15ZALBQPQvvprZ1tPLj7oU https://cassyni.com/events/EYYKGuvZBQXhN6JLn7QuRf?videoPreview=1 PhD student seminarnohttps://cassyni.com/events/EYYKGuvZBQXhN6JLn7QuRf?videoPreview=12022-12-02T03:00:00+00:003050.48Linguistics and Applied Language StudiesIn this final seminar for 2022 we hear from our wonderful PhD students in LALS. Come along to hear about the breadth of research they are undertaking in the School. This informal and celebratory seminar is a fitting way to round off what has been a rich and engaging seminar programme this year! https://cassyni-user-files-prod.s3.amazonaws.com/15ZALBQPQvvprZ1tPLj7oU https://cassyni.com/events/D4d8FVVsGPo5pPMBcxv39F/seminar/qa https://cassyni.com/slides/outline/D4d8FVVsGPo5pPMBcxv39F https://cassyni.com/events/D4d8FVVsGPo5pPMBcxv39F/abstract https://cassyni-user-files-prod.s3.amazonaws.com/C4yDr7UPZxfk2Yj2XAcpNz https://cassyni.com/events/D4d8FVVsGPo5pPMBcxv39F?videoPreview=1 Frege’s Ontological Diagram Completednohttps://cassyni.com/events/D4d8FVVsGPo5pPMBcxv39F?videoPreview=12022-09-07T14:00:00+00:004063.24Logica UniversalisIn a letter of 1891, Frege drew a diagram to illustrate his logical ontology. We observe that it omits features that play an important role in his thought on the matter, propose an extension of the diagram to include them, and compare with a diagram of the ontology of current first-order logic.https://cassyni-user-files-prod.s3.amazonaws.com/C4yDr7UPZxfk2Yj2XAcpNz https://cassyni.com/slides/outline/NSXGR34YZgRTUfnTHjheKP https://cassyni.com/events/NSXGR34YZgRTUfnTHjheKP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QWwTq7fBwmucqS7kT9boFk https://cassyni.com/events/NSXGR34YZgRTUfnTHjheKP?videoPreview=1 Ultra-high-speed time-resolved PIV of turbulent flows using a continuously pulsing fiber lasernohttps://cassyni.com/events/NSXGR34YZgRTUfnTHjheKP?videoPreview=12022-06-21T14:00:00+00:001002.72Experiments in FluidsThe application of a compact pulsed fiber laser for high-speed time-resolved particle image velocimetry (TR-PIV) measurements in the potential core of a turbulent round jet is presented at repetition rates of up to 500kHz. The master oscillator power amplifier laser architecture consists of a pulsable seed diode whose emission is amplified in a Yb-doped fiber. The pulsed laser is operated continuously at repetition rates ranging from 10kHz to 1MHz with adjustable pulse widths at an output power of 50 W. The maximum rated pulse energy of 486μJ is reached at 100kHz, making the laser suitable for measurements of turbulent flows and highly transient phenomena. To demonstrate the feasibility of the laser for flow velocimetry, TR-PIV is conducted in a turbulent round jet. Two different high-speed camera systems are employed: a high-speed CMOS camera running at 200kHz and 400kHz and an in situ storage CCD camera for burst-mode PIV measurements at 500kHz. For the CMOS system, the capability of measuring several characteristic quantities of turbulent flows is discussed with regard to the effects of uncertainty and spatial resolution. The presented system extends the range of suitable laser systems for high-speed PIV measurements offering continuous pulsing at repetition rates of up to 1MHz at a compact footprint. The amount of consecutive images is solely limited by the onboard storage of the camera, which enables unprecedented temporal dynamic ranges.https://cassyni-user-files-prod.s3.amazonaws.com/QWwTq7fBwmucqS7kT9boFk https://cassyni.com/slides/outline/NwAsTii518yWUSKLtAzSah https://cassyni.com/events/NwAsTii518yWUSKLtAzSah/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PvnH3bsXZQKCwxQ4pVGuaW https://cassyni.com/events/NwAsTii518yWUSKLtAzSah?videoPreview=1 A novel experimental facility to impose unsteady pressure gradients on turbulent boundary layers, A simplified photogrammetry procedure in oil-film interferometry for accurate skin-friction measurement over arbitrary geometriesnohttps://cassyni.com/events/NwAsTii518yWUSKLtAzSah?videoPreview=12022-10-11T14:00:00+00:002879.96Experiments in FluidsThe design and characterization of a new removable wind tunnel installation to impose unsteady pressure gradients (PGs) on flat plate turbulent boundary layers (TBLs) are presented. An electropneumatic actuation mechanism was used to rapidly deform a flat ceiling section into an inverted convex bump, producing a temporally strengthening favorable and adverse PG in spatial sequence. The design allowed the vertical extent of deformation and the speed of deformation of the ceiling to be independently varied in a controlled manner to access a series of spatial and temporal strengths of PGs. High-frequency pressure measurements were carried out to characterize the spatio-temporal pressure distributions in the test area for 18 test cases. The resulting range of PGs is presented in terms of non-dimensional parameters relevant to PG TBLs: the acceleration parameter (K), which varied in the range [3,−2.5]×10−6, the Clauser PG parameter (β), in the range ±7, and the non-dimensional gradient of pressure coefficient (dCpd(x/L)), in the range ±2.6. The temporal rates of change of PGs are presented in terms of the reduced frequency (k) and are in the range [0.19, 2.75]. The current and future potential for using this facility to impose a wide range of steady and unsteady PGs in a wind tunnel to enable fundamental studies of various engineering flows of interest are discussed. An accurate and straightforward skin-friction measurement procedure over a three-dimensional (3D) bump geometry is proposed. The procedure employs oil-film interferometry (OFI) measurements coupled with photogrammetry techniques. Photogrammetry is vital for accurate quantitative skin friction measurements over curved surfaces and at different oil flow imaging settings. However, it requires information on surface geometry obtained from multiple reference points on the surface and placing the camera in the exact location and orientation before and after the wind-tunnel run, which complicates the application of OFI. A new simplified method reported here is based on camera calibration algorithms and a flexible small checkerboard. The proposed procedure removes the elaborate steps typically performed in photogrammetry while retaining the same measurement accuracy. In particular, it allows obtaining OFI data without a priori knowledge of model geometry and only taking images after experiments at arbitrary undocumented camera locations. The simplified method was first validated with the Clauser method over a flat surface in a canonical turbulent boundary layer. Then the method was applied to obtain the skin-friction distribution for turbulent flow over 3D Gaussian bump geometry, which exhibits smooth body flow separation. The obtained high-quality benchmark data over the bump geometry are aimed to serve as validation data for numerical simulations for the challenging task of predicting flow separation.https://cassyni-user-files-prod.s3.amazonaws.com/PvnH3bsXZQKCwxQ4pVGuaW https://cassyni.com/slides/outline/HW3DxCbJB6tS5a57HFzebF https://cassyni.com/events/HW3DxCbJB6tS5a57HFzebF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AXZ5Yrwe2qixxa4MDSv7kr https://cassyni.com/events/HW3DxCbJB6tS5a57HFzebF?videoPreview=1 Using Nektar++ to Predict the Noise from Isolated and Installed Jetsnohttps://cassyni.com/events/HW3DxCbJB6tS5a57HFzebF?videoPreview=12022-09-14T12:30:00+00:001663.44NEKTAR++Ever since jet airliners were introduced in the 1950s, jet noise has been a major concern for the airline industry. Today, the amount of noise produced by the turbulent jet is considerably lower than it was 70 years ago. Despite this, jet noise is still the dominant source of aircraft noise during take-off. Therefore, further reductions in jet noise are necessary to meet increasingly stringent noise certification tests, and thereby reduce the negative environmental impacts of aircraft noise. To date, most reductions in jet noise have been realized by increasing the diameter of the engine. This makes it possible to reduce the velocity of the jet, while at the same time keeping the thrust constant. A lower velocity does in turn lead to lower noise levels and better fuel efficiency. However, larger engines must also be placed closer to the wing in order to provide enough ground clearance. This leads to a new source of aircraft noise as the turbulent jet impinges on the wing: installed jet noise. In this talk, I will present some recent efforts on modeling isolated and installed jet noise using the high-order Nektar++ code.https://cassyni-user-files-prod.s3.amazonaws.com/AXZ5Yrwe2qixxa4MDSv7kr https://cassyni.com/slides/outline/VrFL7HmR9YjHyFJvFcZNjP https://cassyni.com/events/VrFL7HmR9YjHyFJvFcZNjP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/C5sHE36e2TitRJuLpiG3L2 https://cassyni.com/events/VrFL7HmR9YjHyFJvFcZNjP?videoPreview=1 Robust Split-Form DGSEM for Hydro- and Magnetohydrodynamicsnohttps://cassyni.com/events/VrFL7HmR9YjHyFJvFcZNjP?videoPreview=12022-12-12T15:00:00+00:003055.8Journal of Computational PhysicsIn this talk, we present the class of split form discontinuous Galerkin methods. The notion of split form refers to different interpretations of the non-linear terms in the fluid dynamics equations. For instance the advective part of the momentum flux can be cast in analytically equivalent forms as $(\rho\,v_1\,v_2)_x = (\rho\,v_1)_x\,v_2 + (\rho\,v_2)_x\,v_1$ or equivalently as $\frac{1}{2}(\rho\,v_1\,v_2)_x + \frac{1}{2}((\rho\,v_1)_x\,v_2 + (\rho\,v_2)_x\,v_1)$ or $(\sqrt{\rho}\,v_1)_x\,(\sqrt{\rho}v_2) + (\sqrt{\rho}\,v_2)_x\,(\sqrt{\rho}v_1)$, with arbitrary many more variants available. While these forms are analytically equivalent for smooth solutions, it is interesting to understand that their discrete forms might have strongly different properties. It turns out that specific underlying split forms of the fluid equations give discontinuous Galerkin (DG) approximations with special favourable properties such as, kinetic energy preservation, energy consistency, pressure equilibrium preservation and even entropy conservation/stability. The most important improvement that can be observed is drastically increased non-linear robustness of the DG discretization, in particular when simulating under-resolved turbulence. A necessary ingredient to retain fully discrete conservation when using split formulations is the so-called summation-by-parts (SBP) property of the discrete derivative and integral operator. It turns out hat specific DG discretizations, such as the Legendre-Gauss-Lobatto (LGL) spectral element method, satisfy the SBP property. We will further discuss in this talk that it is possible to construct compatible low-order finite volume discretizations on the LGL subcell grid, such that a convex blending of the high-order DG method with the robust low-order method is feasible. This allows to construct provably positive hybrid discretizations that enable simulations of problems with strong shock waves, such as e.g. an astrophysical jet with $Ma\approx 2000$. https://cassyni-user-files-prod.s3.amazonaws.com/C5sHE36e2TitRJuLpiG3L2 https://cassyni.com/slides/outline/YKVMLi13LqVnLBnUoJU1TK https://cassyni.com/events/YKVMLi13LqVnLBnUoJU1TK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7qFHg5Wk31ME41Zq63Ghnv https://cassyni.com/slides/outline/KyJsJFLomkahGD1J2cjTE5 https://cassyni.com/events/KyJsJFLomkahGD1J2cjTE5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UvhqXKnwP9LZa9Y4Gd31GA https://cassyni.com/events/KyJsJFLomkahGD1J2cjTE5?videoPreview=1 Opening talknohttps://cassyni.com/events/KyJsJFLomkahGD1J2cjTE5?videoPreview=12022-05-05T15:45:00+00:001734.6Acta Scientiarum MathematicarumNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/UvhqXKnwP9LZa9Y4Gd31GA https://cassyni.com/slides/outline/2gb6ZhBZ1NGomdnQGcAv3X https://cassyni.com/events/2gb6ZhBZ1NGomdnQGcAv3X/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TGgejeqy6mLwffYGNM2bqp https://cassyni.com/events/2gb6ZhBZ1NGomdnQGcAv3X?videoPreview=1 Fluid structure interactions of a microcapsule in flow: when numerical modeling meet experimentsnohttps://cassyni.com/events/2gb6ZhBZ1NGomdnQGcAv3X?videoPreview=12021-11-05T16:00:00+00:003925.16Journal of Fluid MechanicsEncapsulation consists in enclosing an internal medium in a solid semi-permeable membrane to protect it and control the exchanges with the environment. Being at the source of innovative applications in the fields of biotechnologies, pharmacology, or food industry, capsules offer tremendous potential in the process engineering world. But scientific challenges remain to be met, such as finding the optimal compromise between payload and membrane thickness, characterizing the membrane resistance and controlling the moment of rupture. We will explore the challenges to use deformable liquid-core capsules of micrometric size to efficiently transport active material, with a primary focus on health-related applications. Being used suspended in a carrying fluid in flow, microcapsules constitute a formidable problem of complex fluid-structure interactions. I will present how the three-dimensional capsule-flow interactions may be modeled and how these sophisticated numerical models can dialogue with microfluidic experimentations to produce innovative techniques to characterize the mechanical properties of deformable capsules, sort them upon their rigidity or enrich suspensions.https://cassyni-user-files-prod.s3.amazonaws.com/TGgejeqy6mLwffYGNM2bqp https://cassyni.com/slides/outline/3BEhcNq5SpprmQKHs3TiJq https://cassyni.com/events/3BEhcNq5SpprmQKHs3TiJq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/MqZ1E8jCGjFYYFxUMinhtS https://cassyni.com/events/3BEhcNq5SpprmQKHs3TiJq?videoPreview=1 Bringing fluid dynamics to life in the oceannohttps://cassyni.com/events/3BEhcNq5SpprmQKHs3TiJq?videoPreview=12021-03-05T16:00:00+00:003747.32Journal of Fluid MechanicsNo flow, no life. Without movement in the fluid, there would barely be any life in the ocean. Fluid movements allow the continuous supply of nutrients essential to photosynthesis in the sunlit layer of the ocean. This sustains microscopic phytoplankton, an immense biodiversity, and the entire marine food web. In this talk, I will draw attention to a specific class of movements associated with sharp, surface intensified density fronts. I will show that they are disproportionally important to marine life and yet not well accounted for in current anthropogenic climate change projections based on Earth System Models.https://cassyni-user-files-prod.s3.amazonaws.com/MqZ1E8jCGjFYYFxUMinhtS https://cassyni.com/slides/outline/WLvZGbvpzND7niJS3igLub https://cassyni.com/events/WLvZGbvpzND7niJS3igLub/abstract https://cassyni-user-files-prod.s3.amazonaws.com/MJj2J2WfoMKRWQwFo7sKH8 https://cassyni.com/events/WLvZGbvpzND7niJS3igLub?videoPreview=1 Topology optimization of electromagnetic metamaterialsnohttps://cassyni.com/events/WLvZGbvpzND7niJS3igLub?videoPreview=12022-12-20T14:00:00+00:003789.2MetaMATIn recent years, technological advances in nanofabrication have opened new application in the field of photonics. To engineer and develop novel functionalities, rigorous and efficient numerical methods are required. In parallel, tremendous advances in algorithmic differentiation, in part pushed by the intensive development of machine learning and artificial intelligence, have made possible large scale optimization of devices with a few extra modifications of the underlying code. In this presentation I will outline the concepts behind auto-differentiation and give details about topology optimization algorithms. I will present various examples of application in Electromagnetism and metamaterials, such as cloaking and illusion devices. Finally, I will detail the development of three different software libraries for the resolution of Maxwells equations: a Finite Element code with high level interface for problems commonly encountered in photonics, an implementation of the Fourier Modal Method for multilayered bi-periodic metasurfaces and a Plane Wave Expansion Method for the calculation of band diagrams in two dimensional photonic crystals. All of them are endowed with automatic differentiation capabilities and typical inverse design examples will be presented.https://cassyni-user-files-prod.s3.amazonaws.com/MJj2J2WfoMKRWQwFo7sKH8 https://cassyni.com/slides/outline/DYrPajR6fSTHHucRt9QbzM https://cassyni.com/events/DYrPajR6fSTHHucRt9QbzM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Z5B6pbbxkt8TmqkyNiBpS https://cassyni.com/events/DYrPajR6fSTHHucRt9QbzM?videoPreview=1 Fully scattering characterization based on Mutual Extinction and Transparencynohttps://cassyni.com/events/DYrPajR6fSTHHucRt9QbzM?videoPreview=12022-07-04T15:30:00+00:00906.04ETOPIMWavefront shaping is a revolutionary technique which proved that controlling the incident wavefront into a random media we can optimized the intensity in a point on the back, the front or even inside the random media. Recently, we discovered the Mutual Extinction effect, which shows that the crossing interference between coherent incident light and scattered light from different incident light beams modifies the total extinction of the system. Here, we present how to use this effect as a further step of wavefront shaping, controlling the extinction rather the intensity of the light.https://cassyni-user-files-prod.s3.amazonaws.com/Z5B6pbbxkt8TmqkyNiBpS https://cassyni.com/slides/outline/A6KAFwtRbEaeGDJsEV2eTX https://cassyni.com/events/A6KAFwtRbEaeGDJsEV2eTX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6zCpcLiNnnyCre5zaHhyot https://cassyni.com/events/A6KAFwtRbEaeGDJsEV2eTX?videoPreview=1 Plasmon metasurfaces for detection of SARS-CoV-2 Spike Glycoprotein Using Surface-Enhanced Raman Scatteringnohttps://cassyni.com/events/A6KAFwtRbEaeGDJsEV2eTX?videoPreview=12022-07-07T06:00:00+00:002188.04ETOPIMWe present SERS-active metal-dielectric metasurfaces fabricated from metal periodic nanograting deposited on a dielectric substrate. The metasurface consists of a modulated dielectric, which is covered by a thin silver layer. The metasurface operates as an open plasmon resonator. The theory of plasmons excited in the open resonator formed by a metal nanograting is developed. Label-free SERS recording of the receptor-binding domain of SARS-CoV-2 S-glycoprotein is proposed, which allows sensing characteristic protein Raman spectra at the concentrations sufficient for the ultrasensitive detection of viral protein antigens.https://cassyni-user-files-prod.s3.amazonaws.com/6zCpcLiNnnyCre5zaHhyot https://cassyni.com/slides/outline/CZZBVN83nXM8d9nRnAwHBT https://cassyni.com/events/CZZBVN83nXM8d9nRnAwHBT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/YYAmMVdB3fARP82SchU2KG https://cassyni.com/slides/outline/PRr6d2sUqxTLHuJrgH7Qku https://cassyni.com/events/PRr6d2sUqxTLHuJrgH7Qku/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Pgz29hQQvCKs8k3vMPKx9c https://cassyni.com/events/PRr6d2sUqxTLHuJrgH7Qku?videoPreview=1 The curious dynamics of bubble oscillations and collapsenohttps://cassyni.com/events/PRr6d2sUqxTLHuJrgH7Qku?videoPreview=12020-10-30T16:00:00+00:004461.68Journal of Fluid MechanicsBubbles oscillate under the effect of pressure fluctuations, such as those produced by sound waves. When driven into a violent collapse, they can yield strong sound emissions, high-speed jets, and extreme heating - a behaviour known as cavitation. In this lecture, we will present ongoing research efforts to reach a fundamental understanding of the intriguing dynamics of bubbles and the resulting flows, combining ultra-high-speed experiments with theory. The broad aim of this research lies in the quest for harnessing their power for a variety of engineering applications, including ultrasound diagnostics, drug delivery, sonochemistry, surface cleaning and micro-fluidics.https://cassyni-user-files-prod.s3.amazonaws.com/Pgz29hQQvCKs8k3vMPKx9c https://cassyni.com/events/WqaAKHaMRpmAnUqKe9y9Au/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7Nqc2FLnoUL8CjepUAxXcr https://cassyni.com/events/WqaAKHaMRpmAnUqKe9y9Au?videoPreview=1 Logic, Spatial Algorithms and Visual Reasoningnohttps://cassyni.com/events/WqaAKHaMRpmAnUqKe9y9Au?videoPreview=12022-11-30T15:00:00+00:003328.68Logica UniversalisSpatial and diagrammatic reasoning is a significant part not only of logical abilities, but also of logical studies. The authors of this paper consider some novel trends in studying this type of reasoning. They show that there are the following two main trends in spatial logic: (i) logical studies of the distribution of various objects in space (logic of geometry, logic of colors, etc.); (ii) logical studies of the space algorithms applied by nature itself (logic of swarms, logic of fungi colonies, etc.).https://cassyni-user-files-prod.s3.amazonaws.com/7Nqc2FLnoUL8CjepUAxXcr https://cassyni.com/slides/outline/RQSWomTabng6Pcb63EyMBT https://cassyni.com/events/RQSWomTabng6Pcb63EyMBT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5jwRgvY8y7KgNYrdfRbZYA https://cassyni.com/events/RQSWomTabng6Pcb63EyMBT?videoPreview=1 Bio-inspired aerofoil adaptations for the reduction of turbulence interaction noisenohttps://cassyni.com/events/RQSWomTabng6Pcb63EyMBT?videoPreview=12019-05-03T13:00:00+00:002037.6UK Fluids NetworkA dominant source of broadband aeroengine noise arises when the unsteady wakes shed from rotors interact with downstream stators. This so-called leading-edge noise cannot be eliminated, but it can be reduced. By altering the spanwise geometry of the leading edge of an aerofoil it is known through experimental testing that leading-edge noise can be significantly reduced over broadband frequencies. In recent years, a multitude of different shapes have been tested and all are seen to have benefits for different frequency ranges, which may be ideal for the reduction of tonal noise, but the question remains; which design is optimal for broadband noise reduction? This talk presents a theoretical model for leading-edge noise, both for straight edges and serrated edges. Through theoretical optimisation, a set of rules are proposed which lead to an optimal design for broadband leading-edge noise reduction. Experimental data on sample new designs validates the theoretical predictions and illustrates up to an additional 7dB noise reduction verses conventional serrated designs.https://cassyni-user-files-prod.s3.amazonaws.com/5jwRgvY8y7KgNYrdfRbZYA https://cassyni.com/slides/outline/699x17E7Uw5Dd2Yb7wP3VF https://cassyni.com/events/699x17E7Uw5Dd2Yb7wP3VF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UJeEvT3AW2JTexWvShAate https://cassyni.com/events/699x17E7Uw5Dd2Yb7wP3VF?videoPreview=1 Kinetic Brownian motion in the diffeomorphism group of a closed Riemannian manifoldnohttps://cassyni.com/events/699x17E7Uw5Dd2Yb7wP3VF?videoPreview=12021-06-03T16:00:00+00:003325.4DataSıgIn its simplest instance, kinetic Brownian in Rd is a C1 random path (mt, vt) with unit velocity vt a Brownian motion on the unit sphere run at speed a > 0. Properly time rescaled as a function of the parameter a, its position process converges to a Brownian motion in Rd as a tends to infinity. On the other side the motion converges to the straight line motion (= geodesic motion) when a goes to 0. Kinetic Brownian motion provides thus an interpolation between geodesic and Brownian flows in this setting. Think now about changing Rd for the diffeomorphism group of a fluid domain, with a velocity vector now a vector field on the domain. I will explain how one can prove in this setting an interpolation result similar to the previous one, giving an interpolation between Euler’s equations of incompressible flows and a Brownian-like flow on the diffeomorphism group.https://cassyni-user-files-prod.s3.amazonaws.com/UJeEvT3AW2JTexWvShAate https://cassyni.com/slides/outline/CfuYGks6MYCDvqF7Tg3m7 https://cassyni.com/events/CfuYGks6MYCDvqF7Tg3m7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5wFgg6iTQVbFNYFNWDwZxS https://cassyni.com/events/CfuYGks6MYCDvqF7Tg3m7?videoPreview=1 Feedback optimizing model predictive controlnohttps://cassyni.com/events/CfuYGks6MYCDvqF7Tg3m7?videoPreview=12023-01-18T16:00:00+00:002939.32Department of AeronauticsIt is usually desirable to operate systems at economically optimal steady states. Traditionally this is achieved by taking a hierarchical approach to system-wide optimization and control: a steady-state optimization problem is solved to provide optimal setpoints for a lower-level controller to track; the lower-level controller typically employs feedback to reduce the effects of uncertainty. *Feedback optimization* refers to the idea where both functions are performed by one controller: the feedback controller is capable of implicitly tracking the optimal steady-state, without the need for separate optimization or external setpoints. Several proposals have been made, but a common drawback is the lack of constraint handling and performance during the transient. This talk will introduce feedback optimizing model predictive control (FOMPC) as a means to overcome this drawback. The FOMPC formulation is enabled by expressing the KKT conditions for steady-state optimality in subspace form, leading to a tracking (optimality) error that is a function of the measured system output and input rather than a pre-computed setpoint. This tracking error is augmented with a velocity form of the (linear) system dynamics, leading to a formulation and control law that achieves offset-free tracking of the a-priori unknown steady-state optimum and, simultaneously, a transient response that respects constraints and minimizes a quadratic performance criterion. Extensions to the robust case follow. We show how the application to a power system frequency control problem results in an optimal economic steady-state with transient performance that surpasses that of existing feedback optimization methods. https://cassyni-user-files-prod.s3.amazonaws.com/5wFgg6iTQVbFNYFNWDwZxS https://cassyni.com/slides/outline/3fuvmgzVHeJgasJof9agV3 https://cassyni.com/events/3fuvmgzVHeJgasJof9agV3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9csbDQWQg2yMPUfsmR2NXx https://cassyni.com/events/3fuvmgzVHeJgasJof9agV3?videoPreview=1 Alloys of AI and Scientific Computing for Fluid Mechanicsnohttps://cassyni.com/events/3fuvmgzVHeJgasJof9agV3?videoPreview=12023-03-02T15:00:00+00:003757.12Department of Chemical EngineeringOver the last last thirty years we have experienced more than a billion-fold increase in hardware capabilities and a dizzying pace of acquiring and transmitting massive amounts of data. Artificial Intelligence (AI) has been the beneficiaries of these advances and today it is increasingly embedded in technologies that touch every aspect of humanity. However along with the abundance of promise there is an ever increasing amount of hype, in particular regarding the capabilities of learning algorithms to model, predict and control complex fluid mechanics problems. In this talk I would offer a perspective on forming alloys of AI and simulations for the prediction and control of complex flow systems. I will present novel algorithms for learning the Effective Dynamics (LED) of complex flows and a fusion of multi- agent reinforcement learning and scientific computing (SciMARL) for modeling and control of complex flow-structure interactions. I will juxtapose successes and failures and argue that the proper fusion of fluid mechanics knowledge and AI expertise are essential to advance scientific frontiers. https://cassyni-user-files-prod.s3.amazonaws.com/9csbDQWQg2yMPUfsmR2NXx https://cassyni.com/slides/outline/G282vnAcG69YUYYcdW9QdB https://cassyni.com/events/G282vnAcG69YUYYcdW9QdB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/V5Xw3NwYpNzjBKwuBUpZbc https://cassyni.com/events/G282vnAcG69YUYYcdW9QdB?videoPreview=1 Short and long-term prognostic value of intraoperative motor evoked potentials in brain tumor patients: a case series of 121 brain tumor patientsnohttps://cassyni.com/events/G282vnAcG69YUYYcdW9QdB?videoPreview=12023-01-23T21:00:00+00:001778.48Journal of Neuro-OncologyJoin Dr. Randy D'Amico and Dr. Jason Sheehan of the Journal of Neuro-Oncology as they sit down with neurophysiologist Dr. Justin Silverstein from Lenox Hill Hospital to discuss the short and long-term prognostic value of intraoperative motor evoked potentials in brain tumor patients.https://cassyni-user-files-prod.s3.amazonaws.com/V5Xw3NwYpNzjBKwuBUpZbc https://cassyni.com/events/AazPRG3qS44U5gJP2b9cdj/seminar/qa https://cassyni.com/slides/outline/AazPRG3qS44U5gJP2b9cdj https://cassyni.com/events/AazPRG3qS44U5gJP2b9cdj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/D4DBiDjfe9vSQCNJa5ubK4 https://cassyni.com/events/AazPRG3qS44U5gJP2b9cdj?videoPreview=1 Universal Algebraic Logic - Dedicated to the Unity of Sciencenohttps://cassyni.com/events/AazPRG3qS44U5gJP2b9cdj?videoPreview=12023-01-25T15:00:00+00:005095.56Logica UniversalisThis is the presentation of a book that gives a comprehensive introduction to Universal Algebraic Logic. The three main themes are (i) universal logic and the question of what logic is, (ii) duality theories between the world of logics and the world of algebra, and (iii) Tarskian algebraic logic proper including algebras of relations of various ranks, cylindric algebras, relation algebras, polyadic algebras and other kinds of algebras of logic. One of the strengths of our approach is that it is directly applicable to a wide range of logics including not only propositional logics but also e.g. classical first order logic and other quantifier logics. Following the Tarskian tradition, besides the connections between logic and algebra, related logical connections with geometry and eventually spacetime geometry leading up to relativity are also part of the perspective of the book. Besides Tarskian algebraizations of logics, category theoretical perspectives are also touched upon.https://cassyni-user-files-prod.s3.amazonaws.com/D4DBiDjfe9vSQCNJa5ubK4 https://cassyni.com/slides/outline/B5dzTwhMsWcX5SqGd2SQu3 https://cassyni.com/events/B5dzTwhMsWcX5SqGd2SQu3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Lj3b1cDz4SN5yVhUESozJa https://cassyni.com/events/B5dzTwhMsWcX5SqGd2SQu3?videoPreview=1 A first-principles approach to the electronic structure of rare-earth semiconductorsnohttps://cassyni.com/events/B5dzTwhMsWcX5SqGd2SQu3?videoPreview=12023-03-29T18:00:00+00:003738.6School of Chemical and Physical SciencesThe electronic structure of the rare-earth mononitrides LnN (where Ln=rare-earth), which are promising materials for future spintronics applications, is difficult to resolve experimentally due to a strong influence of defects on their transport and optical properties. At the same time, LnN are challenging for theory, since wide semiconducting/semimetallic 2p and 5d bands need to be described simultaneously with strongly correlated 4f states. Here, we calculate the many-body spectral functions and optical gaps of a series of LnN (with Ln = Pr, Nd, Sm, Gd, Tb, Dy, Ho, Er) by a density-functional+dynamical mean-field theory (DFT+DMFT) approach treating the correlated Ln 4f shells within the quasi-atomic Hubbard-I approximation. The on-site Coulomb interaction in the 4f shell is evaluated by a constrained DFT+Hubbard-I approach. Furthermore, to improve the treatment of semiconducting bands in DFT+DMFT, we employ the modified Becke-Johnson semilocal exchange potential. Focusing on the paramagnetic high-temperature phase, we  find that all investigated LnN are pd semiconductors with gap values ranging from 1.02 to 2.14 eV along the series. Despite a pronounced evolution of the Ln 4f states along the series, empty 4f states are invariably found above the bottom of the 5d conduction band. The calculated spectra agree well with those available from x-ray photoemission, x-ray emission and x-ray absorption measurements.https://cassyni-user-files-prod.s3.amazonaws.com/Lj3b1cDz4SN5yVhUESozJa https://cassyni.com/events/VMgbQVfYvAxL4ULnggJSoP/seminar/qa https://cassyni.com/slides/outline/VMgbQVfYvAxL4ULnggJSoP https://cassyni.com/events/VMgbQVfYvAxL4ULnggJSoP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BLMn3VZjaWU73ZJPVYipd4 https://cassyni.com/events/VMgbQVfYvAxL4ULnggJSoP?videoPreview=1 Wastewater-based epidemiology for health and lifestylenohttps://cassyni.com/events/VMgbQVfYvAxL4ULnggJSoP?videoPreview=12023-06-06T07:00:00+00:003650.96Nature WaterWastewater-based epidemiology was widely used to monitor the spreading of COVID-19. We now know that the technique has the potential help us studying a wide range of population health issues and lifestyle aspects, including dietary habits, illegal drug usage or medications. We shall discuss the issue with Sara Castiglioni (Istituto Mario Negri), Xiqing Li (Peking University), Phon Thai (University of Queensland) and Daniel Burgard (University of Puget Sound). * This event is supported by the WeChat channel: Environmentor 2017https://cassyni-user-files-prod.s3.amazonaws.com/BLMn3VZjaWU73ZJPVYipd4 https://cassyni.com/events/3BNpBXQWTdTVW6P9FimFh7/seminar/qa https://cassyni.com/slides/outline/3BNpBXQWTdTVW6P9FimFh7 https://cassyni.com/events/3BNpBXQWTdTVW6P9FimFh7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RmCmc1kAipcvDChrvCE9e6 https://cassyni.com/events/3BNpBXQWTdTVW6P9FimFh7?videoPreview=1 Composite laminates by Double-Double technologynohttps://cassyni.com/events/3BNpBXQWTdTVW6P9FimFh7?videoPreview=12024-02-07T15:00:00+00:005002.72Department of AeronauticsTraditional laminates in Quad has four fixed ply angles in 0, ±45, 90 with variable ply numbers. Double-double (DD) laminates has four variable angles in [±A/±B] with four fixed single plies as the building block, bounded between [0] and [90]. Quad is discrete and unbounded, cannot interpolate and be homogenized; DD, field-based, continuous, can zoom, and easily homogenized for having repeated building blocks 3 or above. Thus DD is simple and easy to use, and naturally symmetric and can taper to save weight and cost that can be 50 percent or more. Layup can be continuous (no stop at mid-plane), with no cross-plying, and the resulting laminate will not warp, esay to inspect, repair and provide hard points. Ply drops can be in singles and placed on the exterior surfaces keeping defects, voids, wrinkles and discontinuities away from the laminate interior. Many self-inflicted complexities of Quad like the stacking sequence, blending, 4-ply limit on nesting, mid-plane symmetry, 10 percent rule, interlaminar ply angles to be no higher than 45 degree, and load-carrying plies to be placed near the center of laminate can be things of the past. Quad laminates can have dozens of stacking sequences; DD has at most 2. For Quad its subjective selection prevents scaling of one design to another. A wing skin can have hundreds of Quad laminates. it can be replaced by one DD. Laminate stiffness can be defined by trace, and its strength by the area of failure envelope. With two single parameters, materials and laminates can be rated. They are equivalent and equal in stature. They are not random. Scaling is possible. One panel for calibration will be sufficient to predict the stiffness and strength of all carbon materials and laminates. It can be shown that the compressive and shear strengths are not sensitive to materials. Like metals only tensile tests will suffice in many cases. Design allowable will no longer be the barrier for innovation and progress in materials and processes. History showed conflicts and resolutions between particle versus wave, AC versus DC, digital versus analog, and others. In a far more modest scale, DD versus Quad is an ongoing conflict. We wish to show why DD will survive because it is simple, rational, and sensical.https://cassyni-user-files-prod.s3.amazonaws.com/RmCmc1kAipcvDChrvCE9e6 https://cassyni.com/events/YLDYK5Q5pDag8btvE4sVsT/seminar/qa https://cassyni.com/slides/outline/YLDYK5Q5pDag8btvE4sVsT https://cassyni.com/events/YLDYK5Q5pDag8btvE4sVsT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EqHzr1yrS2Ngt69HBgsnNA https://cassyni.com/events/YLDYK5Q5pDag8btvE4sVsT?videoPreview=1 Symptom propagation in respiratory pathogens of public health concern: a review of the evidencenohttps://cassyni.com/events/YLDYK5Q5pDag8btvE4sVsT?videoPreview=12024-10-25T13:00:00+00:002649.2Royal Society PublishingSymptom propagation occurs when the symptom set an individual experiences is correlated with the symptom set of the individual who infected them. Symptom propagation may dramatically affect epidemiological outcomes, potentially causing clusters of severe disease. Conversely, it could result in chains of mild infection, generating widespread immunity with minimal cost to public health. Despite accumulating evidence that symptom propagation occurs for many respiratory pathogens, the underlying mechanisms are not well understood. Here, we conducted a scoping literature review for 14 respiratory pathogens to ascertain the extent of evidence for symptom propagation by two mechanisms: dose–severity relationships and route–severity relationships. We identify considerable heterogeneity between pathogens in the relative importance of the two mechanisms, highlighting the importance of pathogen-specific investigations. For almost all pathogens, including influenza and SARS-CoV-2, we found support for at least one of the two mechanisms. For some pathogens, including influenza, we found convincing evidence that both mechanisms contribute to symptom propagation. Furthermore, infectious disease models traditionally do not include symptom propagation. We summarize the present state of modelling advancements to address the methodological gap. We then investigate a simplified disease outbreak scenario, finding that under strong symptom propagation, isolating mildly infected individuals can have negative epidemiological implications.https://cassyni-user-files-prod.s3.amazonaws.com/EqHzr1yrS2Ngt69HBgsnNA https://cassyni.com/events/3ge7k4PXm2PaPHRF5uzAuB/seminar/qa https://cassyni.com/slides/outline/3ge7k4PXm2PaPHRF5uzAuB https://cassyni.com/events/3ge7k4PXm2PaPHRF5uzAuB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3xBCc8bAhVwzSmQBdESJgn https://cassyni.com/events/3ge7k4PXm2PaPHRF5uzAuB?videoPreview=1 Presentation of EAJ Issues 14/1-2 - October 7thnohttps://cassyni.com/events/3ge7k4PXm2PaPHRF5uzAuB?videoPreview=12024-10-07T15:00:00+00:003675.88European Actuarial JournalThe seminar will be opened by Stephane Loisel and closed by Hansjoerg Albrecher.https://cassyni-user-files-prod.s3.amazonaws.com/3xBCc8bAhVwzSmQBdESJgn https://cassyni.com/events/G2rDu9ZejUESGxf44GYu3K/seminar/qa https://cassyni.com/slides/outline/G2rDu9ZejUESGxf44GYu3K https://cassyni.com/events/G2rDu9ZejUESGxf44GYu3K/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UgdsGGZ73jFJ9TfXw23E1k https://cassyni.com/events/G2rDu9ZejUESGxf44GYu3K?videoPreview=1 Follow your heart, even if you can't quite see itnohttps://cassyni.com/events/G2rDu9ZejUESGxf44GYu3K?videoPreview=12024-10-22T03:00:00+00:003462.04The Auckland Bioengineering InstituteCardiac imaging plays a critical role in everyday clinical decision-making. Techniques such as MRI and echocardiography are widely used to characterise cardiac dynamics and mechanics, allowing for rapid assessment of the heart in both research and clinical settings. Ever-evolving technologies, such as artificial intelligence and biophysical modelling, help us do this better, faster, and more accessibly. But how do these findings translate into new guidelines and novel tools for improved healthcare delivery? This talk will serve as a (very) belated PhD exit seminar on the topic of deep learning and 3D echocardiography, and as an introduction to my Pūtahi Manawa Fellowship, with a mission to redefine reference ranges for heart health in Aotearoa. It will cover the "who-am-I, what-am-I, where-am-I, why-am-I, and how-am-I" that underpin my research.https://cassyni-user-files-prod.s3.amazonaws.com/UgdsGGZ73jFJ9TfXw23E1k https://cassyni.com/events/AbiaPdSsuS9Mt6QpTMZ73s/seminar/qa https://cassyni.com/slides/outline/AbiaPdSsuS9Mt6QpTMZ73s https://cassyni.com/events/AbiaPdSsuS9Mt6QpTMZ73s/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DQXFoFzVzWvGDcjzbrVo1x https://cassyni.com/events/AbiaPdSsuS9Mt6QpTMZ73s?videoPreview=1 Celebrating Editorial Impact (2024)nohttps://cassyni.com/events/AbiaPdSsuS9Mt6QpTMZ73s?videoPreview=12024-12-11T09:00:00+00:003697.16Topics at the heart of our communityWith this special end-of-year event, we showcase a wide range of achievements by Springer Nature Editors who have gone above and beyond over the past year, and had a meaningful impact on both their journals and the wider editorial community. This year we are introducing new categories for recognizing editorial excellence: Content Innovation, Research Integrity, Journal Development, Publishing for Progress, and Career Insights.https://cassyni-user-files-prod.s3.amazonaws.com/DQXFoFzVzWvGDcjzbrVo1x https://cassyni.com/slides/outline/B6NBSK6QLthQsrwi3nquKB https://cassyni.com/events/B6NBSK6QLthQsrwi3nquKB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4oyZY4fvDcnWtFvMcst34r https://cassyni.com/events/B6NBSK6QLthQsrwi3nquKB?videoPreview=1 Rapid species-level metagenome profiling and containment estimation with sylphnohttps://cassyni.com/events/B6NBSK6QLthQsrwi3nquKB?videoPreview=12024-11-12T13:30:00+00:00362.0Microbiome Virtual International ForumProfiling metagenomes against databases allows for the detection and quantification of microbes, even at low abundances where assembly is not possible. We introduce sylph (https://github.com/bluenote-1577/sylph), a metagenome profiler that estimates metagenome-genome average nucleotide identity (ANI) through zero-inflated Poisson k-mer statistics, enabling ANI-based taxa detection. Sylph is the most accurate method on the CAMI2 marine dataset, and compared to Kraken2 for multi-sample profiling, sylph takes 10× less CPU time and uses 30× less memory. Sylph’s ANI estimates provide an orthogonal signal to abundance, enabling an ANI-based metagenome-wide association study for Parkinson’s disease against 289,323 genomes, confirming known butyrate-PD associations at the strain level. Sylph takes < 1 minute and 16 GB of RAM to profile against 85,205 prokaryotic and 2,917,521 viral genomes, detecting 30× more viral sequences in the human gut compared to RefSeq. Sylph offers precise, efficient profiling with accurate ANI estimation for even low-coverage genomes.https://cassyni-user-files-prod.s3.amazonaws.com/4oyZY4fvDcnWtFvMcst34r https://cassyni.com/events/LUiHRvuG5x9QtPh6DKsF3b/seminar/qa https://cassyni.com/slides/outline/LUiHRvuG5x9QtPh6DKsF3b https://cassyni.com/events/LUiHRvuG5x9QtPh6DKsF3b/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6xV6zVg2Gnx6ZjowVkhJQN https://cassyni.com/events/LUiHRvuG5x9QtPh6DKsF3b?videoPreview=1 Point Cloud Compression, Super-Resolving and Deblockingnohttps://cassyni.com/events/LUiHRvuG5x9QtPh6DKsF3b?videoPreview=12024-11-07T13:00:00+00:003613.04Journal on Image and Video ProcessingDue to the increased popularity of augmented and virtual reality experiences, as well as 3D sensing for auto-driving, the interest in capturing high resolution real-world point clouds has grown significantly in recent years. Point cloud is a new class of signal that is non-uniform and sparse and this present unique challenges to the signal processing, compression and learning problems. In this talk, we present our multi-scale sparse convolutional learning and Graph Frourier Transform (GFT) based framework for large scale point cloud processing, with applications to the geometry and attributes super-resolution, and dynamic point cloud compression with latent space compensation. The architecture is memory efficient and can learn deep networks to handle large scale point cloud in real world applications. Initial results demonstrated that this framework achieved new state of the art results in geometry super-resolution, attributes deblocking and super-resolving, and dynamic point cloud sequence compression.https://cassyni-user-files-prod.s3.amazonaws.com/6xV6zVg2Gnx6ZjowVkhJQN https://cassyni.com/slides/outline/i5KfxKKQZ6ur7X3JAoqad https://cassyni.com/events/i5KfxKKQZ6ur7X3JAoqad/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XtXsMR15g6Y7yGorRKvsDx https://cassyni.com/events/i5KfxKKQZ6ur7X3JAoqad?videoPreview=1 Origami Metamaterials and Kresling Structures: Theoretical and Experimental Insightsnohttps://cassyni.com/events/i5KfxKKQZ6ur7X3JAoqad?videoPreview=12024-11-06T14:00:00+00:002835.48Department of Aeronautics and AstronauticsThis seminar delves into the captivating fusion of ancient origami art with cutting-edge engineering, showcasing how intricate folding techniques are transforming modern technology. The complex Origami folding patterns offer a versatile framework for fine-tuning both static and dynamic mechanical properties in materials and structures. Through this unique blend of art and science, the seminar highlights two advanced experimental setups aimed at investigating Poisson effects in deployable metamaterials and exploring the mechanics of Kresling tubes—renowned for their bistability and energy absorption potential. The first setup investigates Poisson's ratio across various origami configurations, including the traditional Miura-ori, Eggbox, and the newly developed Morph and Trimorph patterns. Our findings reveal the Morph pattern’s unique ability to reverse Poisson's ratio, seamlessly shifting between positive and negative values through topological transformations. By integrating theoretical models, simulations, and experimental data, we demonstrate the high tunability of Poisson's ratio in origami metamaterials, with consistent results across all approaches. The second setup explores the mechanical behavior of Kresling tubes, composed of even and odd numbers of units with matching or differing chirality. This system features two fixtures that independently control axial displacement (contraction/expansion) and twist, allowing for flexible arrangements within the Kresling array. The insights from this research have broad applications in areas such as soft robotics, mechanical computing, energy absorption, and impact mitigation, opening new possibilities for engineering innovations. https://cassyni-user-files-prod.s3.amazonaws.com/XtXsMR15g6Y7yGorRKvsDx https://cassyni.com/events/E4HRq3VSNzwmjnkrGXNZim/seminar/qa https://cassyni.com/slides/outline/E4HRq3VSNzwmjnkrGXNZim https://cassyni.com/events/E4HRq3VSNzwmjnkrGXNZim/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Agz4A8SzyroVqxUTk2UuEv https://cassyni.com/events/E4HRq3VSNzwmjnkrGXNZim?videoPreview=1 Influence of nitrogen stoichiometry and the role of Sm 5d states in SmN thin filmsnohttps://cassyni.com/events/E4HRq3VSNzwmjnkrGXNZim?videoPreview=12025-03-05T20:00:00+00:002504.04School of Chemical and Physical SciencesWe report a comprehensive study of the synthesis of epitaxial SmN thin films on LaAlO3 (100) by molecular beam epitaxy under slow-growth conditions. By carefully tuning the substrate temperature and the molecular nitrogen partial pressure, we are able to control the nitrogen content of our samples and produce near-stoichiometric, well-ordered SmN thin films. The influence of nitrogen defects on the samarium ion valence and the electronic structure is investigated by x-ray absorption and photoelectron spectroscopy, suggesting that the empty Sm 5*d* states may act as a charge reservoir stabilizing the 4*f*5 configuration in the nitrogen-deficient compound. The spectra also reveal a significant hybridization of the Sm 4*f* and N 2*p* states.https://cassyni-user-files-prod.s3.amazonaws.com/Agz4A8SzyroVqxUTk2UuEv https://cassyni.com/slides/outline/Bb3QbdFpBiBEhdX4ojaCiZ https://cassyni.com/events/Bb3QbdFpBiBEhdX4ojaCiZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/S4h7LXybYbTGYFsh7ur4sx https://cassyni.com/events/Bb3QbdFpBiBEhdX4ojaCiZ?videoPreview=1 Sheet braided versus deep channelized model for pre-vegetation fluvial system: revelations from the study of the Neoproterozoic Ramgiri Formation of Godavari Valley southern Indianohttps://cassyni.com/events/Bb3QbdFpBiBEhdX4ojaCiZ?videoPreview=12025-02-26T15:51:11+00:002424.92Frontiers in Earth ScienceIn recent years, deposits of deep channelized fluvial systems have been documented from some of the pre-Silurian successions, casting doubts about the overwhelming use of sheet braided models of fluvial sedimentation before the advent of land vegetation. This study explores the facies, architecture and paleocurrent pattern of the fluvial succession of Neoproterozoic Ramgiri Formation(i) to understand the surface processes in a pre-vegetation fluvial system,(ii) to examine the existence of sheet-braided or channelised architecture in this succession, and (iii) to understand possible process control that might have resulted in either a sheet braided or channelised architecture in these deposits. The Ramgiri fluvial succession, well-exposed in the southwestern belt of the Godavari Basin of India, varies in preserved thickness from140-500 m. This study examines a transect of ~50 km strike length of the outcrop belt, and subdivides the succession into nine facies and three facies associations supported by sedimentological logs with a cumulative thickness of ~1 km and several hundreds of paleocurrent data. Facies association 1(FA1) consists of stratified, weakly channelized pebble-coble conglomerate alternating with medium-scale trough cross-stratified sheet-like pebbly sandstone units, and facies association 2 (FA2) consists of comparatively finer, pebbly, coarse-grained, laterally extensive sheet sandstones dominated by small trough cross-strata and capped by thin mudstones. Both the facies associations show an abundance of interlayered several decimetres to meter thick, mass flow or hyperconcentrated flow deposits interlayered with cross-stratified units. The regional paleocurrent patterns of these two associations indicate dominant paleoflow to NE, transverse to the basin axis, and are inferred as proximal (FA1) and distal (FA2) megafan deposits. The coarser gain size, poorly channelised sheet-braided architecture, evidence of rapidly waning flow, and abundant interlayered thin mass flow/hyperconcentrated flow deposits in these two associations reflect the character of pre-vegetation surface processes on the Ramgiri megafans. In contrast, the facies association 3 (FA3) contains up to ~3m deep channel scours and large simple and compound bedforms and downcurrent accreting bars. The overall paleoflow of FA3 is towards SE, parallel to the basin axis, and represents deposition from a lower-gradient, perennial, sandy braided river system. We infer that the flow and their deposits were sheet-like on the megafan because of its comparatively steeper gradient leading to the flow attenuation and rapid widening on a non-cohesive sandy substrate, whereas lower-gradient, perennial axial drainage of FA3, fed by numerous transverse megafan drainages gave rise to deeper, wider channels and large compound bedforms/bars. The geophysical and tectonic evidence from the Godavari half-graben, indicate that the transverse megafans developed on the roll-over anticline of the passive SW margin of the half-graben. In contrast, the adjacent axial depression was characterized by a wider, deeper drainage, resulting in the simultaneous existence of sheet-braided as well as thicker channelled deposits in the Ramgiri Formation. We infer surface slope and discharge regime, controlled by the paleogeomorphology and the paleoclimate were the main control of variable architecture in Ramgiri fluvial deposits.https://cassyni-user-files-prod.s3.amazonaws.com/S4h7LXybYbTGYFsh7ur4sx https://cassyni.com/events/PwH8sLwpZWwpjnTH4f5NVK/seminar/qa https://cassyni.com/slides/outline/PwH8sLwpZWwpjnTH4f5NVK https://cassyni.com/events/PwH8sLwpZWwpjnTH4f5NVK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/MRmneFnWSNM8qbpsvmU9wk https://cassyni.com/events/PwH8sLwpZWwpjnTH4f5NVK?videoPreview=1 SDG 3: Implementation of Evidence-Based Practices for Improving Maternal and Neonatal Healthnohttps://cassyni.com/events/PwH8sLwpZWwpjnTH4f5NVK?videoPreview=12025-03-19T16:00:00+00:003409.64Springer Nature Sustainable Development Goals ProgrammeThis webinar focuses on strategies for implementing evidence-based practices that will make a real difference to improving maternal and neonatal health, which ties in closely with SDG targets 3.1 and 3.2 in particular. We invite you to read related content in the collection on [Implementation of Evidence-Based Practices for Improving Maternal and Neonatal Health](https://www.biomedcentral.com/collections/IEBP), published in [Implementation Science](https://implementationscience.biomedcentral.com/) and [Implementation Science Communications](https://implementationsciencecomms.biomedcentral.com/). The Guest Editors of the collection - Michelle H. Moniz, Rebecca Hamm, and Jennifer Callaghan Koru - are chairing the event, with the Springer Nature SDG3 chair, Fiona Pring, introducing the event.https://cassyni-user-files-prod.s3.amazonaws.com/MRmneFnWSNM8qbpsvmU9wk https://cassyni.com/events/JW9VMpq3jUrkLvD3Tk5aVs/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JTFArTXo8yWEUSDD4sCkSr https://cassyni.com/events/JW9VMpq3jUrkLvD3Tk5aVs?videoPreview=1 The human functioning revolutionnohttps://cassyni.com/events/JW9VMpq3jUrkLvD3Tk5aVs?videoPreview=12023-12-05T15:00:00+00:005332.24Frontiers in ScienceHuman functioning constitutes a rethinking of health that goes beyond disability and disease. It encompasses the activities that people perform in their everyday lives and is the bridge that links health to individual well-being and societal welfare. In this Frontiers Forum Deep Dive session on 5 December 2023, Professors Gerold Stucki, Jerome Bickenbach, Sara Rubinelli, and other renowned researchers, examined the action required to fully realize the opportunities offered by this rethinking of health. The session brought together the authors of the Frontiers in Science lead article ‘The human functioning revolution: implications for health systems and sciences’ in which they present a strategy for implementing human functioning across health systems and policies to effectively link health and well-being. https://cassyni-user-files-prod.s3.amazonaws.com/JTFArTXo8yWEUSDD4sCkSr https://cassyni.com/slides/outline/Jzo6QWUaAwQoLgjw4BNNmB https://cassyni.com/events/Jzo6QWUaAwQoLgjw4BNNmB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RpXA2nLZHfKdpXfPsYvQ7G https://cassyni.com/events/Jzo6QWUaAwQoLgjw4BNNmB?videoPreview=1 The origin and evolution of stomatanohttps://cassyni.com/events/Jzo6QWUaAwQoLgjw4BNNmB?videoPreview=12024-10-21T13:00:00+00:001679.88The New Phytologist FoundationWhen did stomata first evolve? What was their function in the first land plants? Stomata are a fundamental aspect of the land plant body plan, yet understanding their evolution requires a careful appraisal of the fossil record within a robust phylogenetic framework. I will discuss how we have combined phylogenomics, comparative genomics, and palaeontology with analyses of physiology and gene expression to reveal the origins and trajectory of stomatal evolution.https://cassyni-user-files-prod.s3.amazonaws.com/RpXA2nLZHfKdpXfPsYvQ7G https://cassyni.com/slides/outline/RusZ45XvKMAaqVjWRcwJus https://cassyni.com/events/RusZ45XvKMAaqVjWRcwJus/abstract https://cassyni-user-files-prod.s3.amazonaws.com/84LC8DiyVQhZiLdVzR2gkW https://cassyni.com/events/RusZ45XvKMAaqVjWRcwJus?videoPreview=1 Supplier Diversity Issues Impacting Black Entrepreneurs in Floridanohttps://cassyni.com/events/RusZ45XvKMAaqVjWRcwJus?videoPreview=12024-11-20T17:00:00+00:00661.64Center for Black Entrepreneurship, Spelman CollegeNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/84LC8DiyVQhZiLdVzR2gkW https://cassyni.com/events/UP7aHVmYWdw5CSD4yJqwdo/seminar/qa https://cassyni.com/slides/outline/UP7aHVmYWdw5CSD4yJqwdo https://cassyni.com/events/UP7aHVmYWdw5CSD4yJqwdo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CMwtgjp9yddmeKBa97ZJjQ https://cassyni.com/events/UP7aHVmYWdw5CSD4yJqwdo?videoPreview=1 Localisation of flexural waves in thin elastic plates by complex engineered surfaces: from aperiodicity to QNMsnohttps://cassyni.com/events/UP7aHVmYWdw5CSD4yJqwdo?videoPreview=12025-02-11T14:00:00+00:003483.04MetaMATPrecise control of mechanical wave propagation and confinement of energy plays an important role in contemporary applications reliant on the utilisation of wave energy. In this talk, I will review some geometric structures featuring localised eigenstates that might be applicable as wave trapping devices for elastic waves. Aperiodic crystals, due to their properties linked to topological invariants, are good candidates for energy confinement. Additionally, the relevance of bound states in the continuum (BICs) as wave trapping devices will be discussed, given the fact that these modes are naturally isolated from the medium, preventing leakage of energy. Numerical examples will be given using multiple scattering theory applied to flexural waves in a KL plate. Finally, quasinormal mode expansion will be described for this kind of problems, showing the efficiency of this technique when simulating finite clusters in open systems, and providing an insight on QVHE topological interface states.      https://cassyni-user-files-prod.s3.amazonaws.com/CMwtgjp9yddmeKBa97ZJjQ https://cassyni.com/events/7dtCLnbW5Qfp4SknhBvbkH/seminar/qa https://cassyni.com/slides/outline/7dtCLnbW5Qfp4SknhBvbkH https://cassyni.com/events/7dtCLnbW5Qfp4SknhBvbkH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QXJnvF2U61J4j9FFvYV4Z4 https://cassyni.com/events/7dtCLnbW5Qfp4SknhBvbkH?videoPreview=1 Our Approach to Integrity Investigationsnohttps://cassyni.com/events/7dtCLnbW5Qfp4SknhBvbkH?videoPreview=12025-02-20T09:00:00+00:003577.08Topics at the heart of our communityHow can Springer Nature support Editors when concerns are raised about a paper or papers in your journal? Join Tim Kersjes, from the Springer Nature Research Integrity Group, alongside Jo Cox and Alice Henchley from our Legal and Communications teams, to hear more about how Springer Nature conducts investigations and the resources available to our Editors. https://cassyni-user-files-prod.s3.amazonaws.com/QXJnvF2U61J4j9FFvYV4Z4 https://cassyni.com/events/4BLy214q1CoB2kTE3XYeDT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LiG52nRiPAyuG344QZkhMY https://cassyni.com/slides/outline/2CnAwtzcejWWVGyBHwkyfj https://cassyni.com/events/2CnAwtzcejWWVGyBHwkyfj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9RVLctFRBzM2yRYjZhL9Jn https://cassyni.com/events/2CnAwtzcejWWVGyBHwkyfj?videoPreview=1 Design Optimization of Subcavitating Hydrofoils for America's Cup Class Yachtsnohttps://cassyni.com/events/2CnAwtzcejWWVGyBHwkyfj?videoPreview=12024-12-05T15:00:00+00:002297.0JKW Symposium TeamCavitation on foils and appendages is a significant design consideration for sailing yachts like the America’s Cup AC75 monohulls and the SailGP F50 catamarans because they achieve speeds in excess of 50 kts. As speed or lift increases past cavitation onset conditions, the vapor cavities grow and can adversely affect lift and drag. For design optimization, it means we need constraints to control the minimum surface pressures on the foil, which we do using the Kreisselmeier–Steinhauser (KS) aggregation function. This approach works with our viscous fluid solver and gradientbased optimization toolchain. Multipoint optimizations with the cavitation constraint function were used to optimize hydrofoil sections over a range of flap angles, lift coefficients, and speeds starting from baseline ‘seed’ profiles that were considered good subcavitating profiles. Consideration of multiple flow conditions makes resulting profiles more robust against flow separation. We also explore the effect of plain trailing edge (TE) flaps (and flap chord length) as part of the section design where we optimize deflection angles in addition to the profile shape. Independent analyses of the optimized profiles using the XFOIL viscous 2D solver helped verify that the optimizer was not exploiting flaws in the computational models. Our results demonstrate that the multipoint, cavitation-constrained methodology works for gradient-based optimization of subcavitating hydrofoil sections with flaps. When combined with judgment and some expertise for setting objectives and constraints, this methodology can be used to design high-performance hydrofoils.https://cassyni-user-files-prod.s3.amazonaws.com/9RVLctFRBzM2yRYjZhL9Jn https://cassyni.com/events/5fKQGgXHiwP9WyGjwc8wCZ/seminar/qa https://cassyni.com/slides/outline/5fKQGgXHiwP9WyGjwc8wCZ https://cassyni.com/events/5fKQGgXHiwP9WyGjwc8wCZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2cYDuDskKAyDABheXg5Etn https://cassyni.com/events/5fKQGgXHiwP9WyGjwc8wCZ?videoPreview=1 Bio-Inspired Composites: Unlocking the Potential of Hierarchical Natural Fibresnohttps://cassyni.com/events/5fKQGgXHiwP9WyGjwc8wCZ?videoPreview=12025-02-20T15:00:00+00:003604.68Department of AeronauticsNature has long been a source of inspiration for high-performance materials, offering composites with intricate hierarchical architectures that provide exceptional mechanical properties. While natural fibres such as flax, hemp, and bamboo have been used for centuries, their full potential in structural and high-performance applications remains largely untapped. By leveraging bio-inspired design and advanced processing techniques, we can engineer fibres with tailored properties, creating sustainable alternatives to synthetic composites. At the Luxembourg Institute of Science and Technology, my research focuses on developing and enhancing natural fibres for next-generation composites. By studying the complex structures of biological materials, we design hierarchical fibres with optimised mechanical properties, bridging the gap between natural and synthetic reinforcements. Our recent work on bamboo fibre densification has resulted in tensile strengths approaching 2000 MPa, comparable to specific carbon fibre properties, offering a viable alternative for demanding applications. Additionally, we explore bio-inspired surface treatments, such as dopamine-based coatings, to enhance interfacial bonding, as well as self-healing mechanisms to improve durability in harsh environments. Beyond material design, we are also advancing the scalability and processability of natural fibres. Our research includes developing high-quality bamboo fibre tapes and textiles, exploring fibre-welding techniques for continuous reinforcements, and integrating natural fibres into 3D-printed composites. These innovations aim to address key challenges in natural fibre composites, making them more durable, versatile, and industrially viable. This talk will present recent advancements in these areas, highlighting how a combination of bio-inspiration, engineering, and innovative processing can unlock the full potential of natural fibres. By bridging the gap between nature and technology, we aim to develop sustainable, high-performance composites that challenge the dominance of traditional synthetic materials. https://cassyni-user-files-prod.s3.amazonaws.com/2cYDuDskKAyDABheXg5Etn https://cassyni.com/slides/outline/4g2CBKEEr2GzrDSjqdfcPf https://cassyni.com/events/4g2CBKEEr2GzrDSjqdfcPf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7yAaoSi1RGwkfxY8EB3vuL https://cassyni.com/events/4g2CBKEEr2GzrDSjqdfcPf?videoPreview=1 Shock Capturing via Limiting for High-Order Methodsnohttps://cassyni.com/events/4g2CBKEEr2GzrDSjqdfcPf?videoPreview=12024-12-07T17:00:00+00:002319.72JKW Symposium TeamHigh-order methods such as discontinuous Galerkin (DG), spectral, and flux reconstruction (FR) offer excellent accuracy in smooth regions but suffer from spurious oscillations near shocks. Standard monotonicity-preserving limiters suppress these oscillations but often degrade accuracy near smooth extrema to first order. This talk introduces a new limiting technique that expands traditional monotonicity bounds—without enlarging the stencil—to preserve accuracy near smooth extrema while still effectively suppressing oscillations near discontinuities. The limiter is partly motivated by an analysis of the DG solution at a discontinuity, which reveals that the mode of degree k grows at a rate of 2k+1. This modal growth rate arises from formulating the DG method within the FR framework and expressing the derivatives of the Radau polynomials through a recurrence relation. This insight into modal behavior motivates a new strategy: applying the expanded limit not only to the magnitude of the linear mode but also to the sum of all modal magnitudes. Unlike standard methods that rely on smoothness detection—which can fail and compromise continuous data dependence—our approach maintains continuous dependence and can be applied globally. For efficiency, we also introduce criteria to skip limiting in smooth regions where it has no effect. The resulting algorithm is simple to implement and is validated through numerical tests on the advection and Euler equations. https://cassyni-user-files-prod.s3.amazonaws.com/7yAaoSi1RGwkfxY8EB3vuL https://cassyni.com/events/D53TxwEAJogz1YoCuUzfcZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EufqrP6BdQQoVXGQrjhtMk https://cassyni.com/slides/outline/FYHVCMTnW6TUNVGmTAuJLV https://cassyni.com/events/FYHVCMTnW6TUNVGmTAuJLV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/SxFBgz9373VBc3k3bYMo4i https://cassyni.com/events/FYHVCMTnW6TUNVGmTAuJLV?videoPreview=1 17th international Biometals Webinarsnohttps://cassyni.com/events/FYHVCMTnW6TUNVGmTAuJLV?videoPreview=12025-07-01T13:00:00+00:005134.6BioMetalsThe total zinc content of serum or plasma is the most frequently used indicator of zinc status in humans. Important aspects, such as availability and chemical speciation, are neglected by this biomarker. Zinc ions that are tightly bound by proteins, such as serum albumin, might not be immediately available to exert their multiple biological functions on the cellular level, e.g., by regulating immune cell activity and inflammation. To quantify bioavailable zinc, also called the free, i.e. readily available, fraction of zinc, we developed a method based on Zinpyr-1, a low molecular weight fluorescent probe for Zn2+ ions. This technique has been applied to analyze fZn in serum, plasma, and liquor samples from animal models and multiple patient cohorts, investigating possible associations with nutritional preferences (comparing omnivores, flexitarians, vegetarians, and vegans), ageing, the antibody response after vaccination, as well as with disease status in type 2 diabetes, neurological and cardiovascular disease, colorectal cancer, COVID, and spinal cord injury. Herein, fZn did not correlate with total zinc levels in many cohorts, indicating that it is an independent and differentially regulated species. It may be useful as a potential disease marker as well as instrumental for understanding the biological functions of zinc and its mechanistic role in physiology and pathophysiology. Zinc finger proteins (ZFs) are a large class of proteins that use zinc as structural cofactors. ZFs have critically important roles in modulating transcription and translation. ZF proteins contain one or more domains with four conserved cysteine and/or histidine residues that serve as ligands for zinc. Upon zinc binding, ZFs fold and function. The accepted dogma for the role of ZF proteins is that they are structural sites; however, there is emerging evidence for reactivity of ZFs with endogenous signaling molecules including H2S. H2S is a gasotransmitter that plays key roles in biology ranging from neuromodulation to regulation of inflammation. The molecular targets of H2S include heme and non-heme iron proteins, reactive oxygen-, sulfur-, and nitrogen species, and cysteine residues on proteins. The interaction of H2S with protein cysteine residues (P-SH) involves a post-translational modification (PTM) called persulfidation - the addition of sulfur to protein cysteine residues (P-SH  P-SSH). We have discovered that ZF proteins are targets of H2S in cells, using a persulfide specific chemoselective proteomics approach. The mechanism by which ZFs are persulfidated has been evaluated in several ZF proteins, and we have discovered a common mechanism that involves Zn serving as a conduit to bring H2S and O2 together for electron transfer. These results as well as work on how inflammation drives H2S signaling via ZF persulfidation will be presented. https://cassyni-user-files-prod.s3.amazonaws.com/SxFBgz9373VBc3k3bYMo4i https://cassyni.com/events/HWuXViZmfHbxcgFQ6hhgPf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JThLGSsqm95soRoxABpzS https://cassyni.com/slides/outline/88b3cjGoKb5QhcCvgxsjqP https://cassyni.com/events/88b3cjGoKb5QhcCvgxsjqP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/MaGn7UZ8WmeUQZvKHAdYh4 https://cassyni.com/events/88b3cjGoKb5QhcCvgxsjqP?videoPreview=1 Multi-* mathematics and simulations of coupled processes the Arcticnohttps://cassyni.com/events/88b3cjGoKb5QhcCvgxsjqP?videoPreview=12025-09-18T12:00:00+00:002544.04MOX Laboratory - Department of MathematicsWe present our joint work with many collaborators on multi-physics and multiple scales, with focus on processes in the Arctic, a vast and complex environment of great current interest, with physical models sharing some (but not all) features with high alpine environments and other cold regions. Our interest is in robust, accurate and conservative computational schemes for the multi-physics: thermal, flow and mechanical deformation (TpHM) in the snow, ice and soils responding to the forcings from the environment for which the data is sparse. The models account for multiple phases and components and present challenges due to the presence of free boundary e.g. of freezing/thawing/sublimation, strong dependence of constitutive parameters on the micro-physics of TpHM, disparate time scales, and micro- and macro heterogeneity. We show how to build constitutive relationships for Darcy scale models from the first principles at the interface- and pore-scale by a combination of mathematically rigorous theory, practical computational upscaling, and surrogate data science tools. We illustrate with simulations of practical scenarios. This initiative is part of the “Ph.D. Lectures” activity of the project "Departments of Excellence 2023-2027" of the Department of Mathematics of Politecnico di Milano. This activity consists of seminars open to Ph.D. students, followed by meetings with the speaker to discuss and go into detail on the topics presented at the talk.https://cassyni-user-files-prod.s3.amazonaws.com/MaGn7UZ8WmeUQZvKHAdYh4 https://cassyni.com/events/PSGSLUbmtNMEV4ksxoC3ED/seminar/qa https://cassyni.com/slides/outline/PSGSLUbmtNMEV4ksxoC3ED https://cassyni.com/events/PSGSLUbmtNMEV4ksxoC3ED/abstract https://cassyni-user-files-prod.s3.amazonaws.com/C4hfJhzyP8TwArbLMMoUmk https://cassyni.com/events/PSGSLUbmtNMEV4ksxoC3ED?videoPreview=1 Turning Wastewater Treatment Plants into Sentinels of Public Healthnohttps://cassyni.com/events/PSGSLUbmtNMEV4ksxoC3ED?videoPreview=12025-05-13T08:00:00+00:003432.92ElsevierThis presentation explores the transformative potential of Wastewater-Based Epidemiology (WBE) in public health surveillance. Urban wastewater carries diverse information on community health, lifestyle habits, and disease trends. By analyzing sewage, WBE enables early detection of pathogens, including SARS-CoV-2, and tracks their spread among populations. Historical milestones and recent applications have illustrated its effectiveness, particularly during the COVID-19 pandemic. Cyprus's national surveillance programs highlight the real-time utility of WBE in monitoring virus variants and antibiotic resistance determinants, while emerging initiatives including surveillance at airports and localized urban geographical points, showcase the WBE expanding applications. Overall, WBE is poised to be a core component of the global public health infrastructure.https://cassyni-user-files-prod.s3.amazonaws.com/C4hfJhzyP8TwArbLMMoUmk https://cassyni.com/events/8cpJwyC2idjcB8UAx9NJgV/seminar/qa https://cassyni.com/slides/outline/8cpJwyC2idjcB8UAx9NJgV https://cassyni.com/events/8cpJwyC2idjcB8UAx9NJgV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AejkhujB1VX6WTQ7bnu3cz https://cassyni.com/events/8cpJwyC2idjcB8UAx9NJgV?videoPreview=1 Targeted Protein Degradation: New Horizons in Medicinal Chemistry Toolsnohttps://cassyni.com/events/8cpJwyC2idjcB8UAx9NJgV?videoPreview=12025-06-20T09:45:00+00:001602.04Anti-Cancer Agents in Medicinal ChemistryTargeted protein degradation (TPD) has emerged as a transformative strategy in modern medicinal chemistry, expanding the frontiers of drug discovery. By moving beyond traditional occupancy-driven pharmacology, TPD harnesses the cell's intrinsic proteostasis mechanisms—namely the ubiquitin-proteasome system and lysosomal degradation pathways—to selectively eliminate disease-associated proteins. Key innovations include PROTACs, TRAFTACs, dual PROTACs, and PROTABs, each leveraging event-driven mechanisms to catalytically degrade target proteins with enhanced selectivity and reduced dosing requirements. Molecular glue degraders and tag-based degron systems further diversify the TPD toolkit, enabling the modulation of previously “undruggable” targets. Meanwhile, advances like LYTACs and CIDEs open new avenues for degrading extracellular and membrane proteins. These evolving chemical modalities promise superior therapeutic potential, especially in oncology, by overcoming drug resistance and enhancing pharmacological precision. As over 20 TPD-based therapeutics have entered clinical trials, the approach stands as a promising modern medicinal chemistry tool.https://cassyni-user-files-prod.s3.amazonaws.com/AejkhujB1VX6WTQ7bnu3cz https://cassyni.com/slides/outline/D6FFiVA8mS6R6HGPykgER https://cassyni.com/events/D6FFiVA8mS6R6HGPykgER/abstract https://cassyni-user-files-prod.s3.amazonaws.com/ACbdxokScGCZSySmbsmKiE https://cassyni.com/events/D6FFiVA8mS6R6HGPykgER?videoPreview=1 From curiosity to capability: A practical blueprint for safe Gen AI adoptionnohttps://cassyni.com/events/D6FFiVA8mS6R6HGPykgER?videoPreview=12025-03-31T00:00:00+00:004032.32Business SchoolIn late 2023, the true potential of Generative AI was still shrouded in uncertainty, prompting Air New Zealand to launch an open call to leaders: “If you can imagine it, we’ll try it.” In this session, we will walk you through how a small squad in Air New Zealand rapidly evaluated diverse use cases capturing technical requirements, risks, and business value for each idea. The result? A culture that embraces curiosity, mitigates risk, and quickly learns from Gen AI’s evolving capabilities.https://cassyni-user-files-prod.s3.amazonaws.com/ACbdxokScGCZSySmbsmKiE https://cassyni.com/events/J1AQwaztThBvutyGZZ2R9f/seminar/qa https://cassyni.com/slides/outline/J1AQwaztThBvutyGZZ2R9f https://cassyni.com/events/J1AQwaztThBvutyGZZ2R9f/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9N6Qy1bC1ieVJkJeX9h58z https://cassyni.com/events/J1AQwaztThBvutyGZZ2R9f?videoPreview=1 The Rise of AI in the Publishing Landscapenohttps://cassyni.com/events/J1AQwaztThBvutyGZZ2R9f?videoPreview=12025-07-17T08:00:00+00:001660.04Topics at the heart of our communityArtificial Intelligence (AI) has transformed the research publishing landscape. As an editor, you are now faced with AI-related challenges, some of which include image integrity, paper mills, and plagiarism. Join Tamara Welschot, Head of Research Integrity, Prevention, Cristiano Matricardi, Head of Content Innovation, who will discuss how we are harnessing the power of AI to support our editors in meeting the increasing demands for innovation and quality within scholarly publishing. https://cassyni-user-files-prod.s3.amazonaws.com/9N6Qy1bC1ieVJkJeX9h58z https://cassyni.com/events/LUQSB1EWeyxRGqSq7Ew3sb/seminar/qa https://cassyni.com/slides/outline/LUQSB1EWeyxRGqSq7Ew3sb https://cassyni.com/events/LUQSB1EWeyxRGqSq7Ew3sb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9G414DfDQx1NHk8Bu1KVBU https://cassyni.com/events/LUQSB1EWeyxRGqSq7Ew3sb?videoPreview=1 Humanistic Demands and the Role of Chance in Business: A Plea for Mercynohttps://cassyni.com/events/LUQSB1EWeyxRGqSq7Ew3sb?videoPreview=12025-06-25T14:00:00+00:005184.88Logica UniversalisThe paper explores the fundamental difference between humanistic logic and business logic. Despite the common belief humanistic ethics is hierarchically above business ethics - what is represented in the demand for social responsibility of business - they are irreducible games. Departing from the Greek concept of ethos as character, or guiding beliefs of a person, community or system, the idea is to show how each of the spheres operate with their specific rules and principles, emphasizing the contrasting role of chance in each of the games. While humanism tends to minimize the importance of chance, disregarding the impact of randomness throughout an individual’s life, in health and wealth for instance, businesses operate under the assumption that chance is decisive and should be accounted for. While humanism obliterates chance by supposing an initial equality that should be kept at all costs, business ethics departs from an inherent competitiveness and attributes a monetary value for the undertaken risks. The article is based on a Wittgensteinian way of analysis and will examine a scene in Merchant of Venice, where Shylock is asked to show mercy to Antonio. In court, the judge explicitly marks the difference between the two games, one that had been agreed upon between the two parties and a supposedly broader one, and hierarchically superior, that is not demanded by the law, but by the heart, or why not say, by God. The reference to the Shakespearean play shows how the condemnation of usury and the requirement for fairness in a christian/western/humanistic context often contradicts the rules of the game we play when in business mode.https://cassyni-user-files-prod.s3.amazonaws.com/9G414DfDQx1NHk8Bu1KVBU https://cassyni.com/events/Vs7deojtdjSpWMVD54GQXo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/422X62WGFnBfkTK9fiaTGS https://cassyni.com/events/QvdbByGeF9uo7Fms4aZQof/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HPfdEDUJXeDVJ8GnBu2ezS https://cassyni.com/events/2hTQ7DA2VYzLJjxh63swqw/seminar/qa https://cassyni.com/slides/outline/2hTQ7DA2VYzLJjxh63swqw https://cassyni.com/events/2hTQ7DA2VYzLJjxh63swqw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EV3qb8SEjAHpeqWUDYTGbG https://cassyni.com/events/2hTQ7DA2VYzLJjxh63swqw?videoPreview=1 Modeling and estimation of a continuous flexible structure using the Theory of Functional Connectionsnohttps://cassyni.com/events/2hTQ7DA2VYzLJjxh63swqw?videoPreview=12025-04-15T10:00:00+00:003661.04Department of AeronauticsThis talk presents a novel method for modeling and estimating the dynamics of a continuous structure based on a limited number of noisy measurements. The goal is reached using a Kalman filter in synergy with the recently developed mathematical framework known as the Theory of Functional Connections (TFC). The TFC allows to derive a functional expression capable of representing the entire space of the functions that satisfy a given set of linear and, in some cases, nonlinear constraints. The proposed approach exploits the possibilities offered by the TFC to derive an approximated dynamical model for the flexible system using the Lagrangian mechanics. The result is a representation of the structural dynamics using a finite number of states, in contrast to the infinite-dimensional model that would be obtained by application of the traditional continuum mechanics models that are based on sets of partial differential equations.https://cassyni-user-files-prod.s3.amazonaws.com/EV3qb8SEjAHpeqWUDYTGbG https://cassyni.com/slides/outline/3C719toYw1YPJWVagVAk7F https://cassyni.com/events/3C719toYw1YPJWVagVAk7F/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2i59aUpPEb7xJuER6dZdta https://cassyni.com/events/3C719toYw1YPJWVagVAk7F?videoPreview=1 Data-Driven Benchmarking and Assessment in Researchnohttps://cassyni.com/events/3C719toYw1YPJWVagVAk7F?videoPreview=12025-01-15T10:00:00+00:003709.8Academic Publishing in EuropeA dozen years after the San Francisco Declaration on Research Assessment, this panel will critically discuss the evolution of the process. A particular focus will be on quantitative indicators and their application alongside subjective approaches, as well as the continued dominant role of journal publishing in Research Assessment.https://cassyni-user-files-prod.s3.amazonaws.com/2i59aUpPEb7xJuER6dZdta https://cassyni.com/slides/outline/DZih8FPa9dAoq1nihb7dnm https://cassyni.com/events/DZih8FPa9dAoq1nihb7dnm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/N1ZgBFouut2vy2pU2AxBKU https://cassyni.com/events/DZih8FPa9dAoq1nihb7dnm?videoPreview=1 Using tasks as a lever to achieve curriculum aspirationsnohttps://cassyni.com/events/DZih8FPa9dAoq1nihb7dnm?videoPreview=12025-09-26T01:10:00+00:002847.52Linguistics and Applied Language StudiesMy PhD research investigates the implementation of the Global Success Grade 10 English textbook in rural Vietnamese high schools in the Mekong Delta from a task-based language teaching (TBLT) perspective. In this talk I will focus on a case study of one school (‘Valley School’). The study employed a three-phase exploratory design: Phase 1 - textbook analysis; Phase 2 – analysis of textbook implementation, and Phase 3 – a teacher professional learning intervention on TBLT at the Valley School. In reporting on my findings, I will discuss data from each of the three phases of the research, and offer some tentative conclusions as to the feasibility of TBLT in rural contexts as well as insights for improving textbook design and teacher training to enhance English language instruction in Vietnam.https://cassyni-user-files-prod.s3.amazonaws.com/N1ZgBFouut2vy2pU2AxBKU https://cassyni.com/slides/outline/CaRV2t6XGi4fAFxibceJys https://cassyni.com/events/CaRV2t6XGi4fAFxibceJys/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FhTcpXW2zA9Hh5cTV9rtfp https://cassyni.com/events/CaRV2t6XGi4fAFxibceJys?videoPreview=1 Exploring the link between microstructure, order, and toughness in bioinspired compositesnohttps://cassyni.com/events/CaRV2t6XGi4fAFxibceJys?videoPreview=12025-06-06T13:00:00+00:002817.04UK Metamaterials NetworkComposites with intricate microstructures are ubiquitous in the natural world where they fulfil the specific functional demands imposed by the environment. For instance, nacre presents a fracture toughness 40 times higher than its main constituent, a crystalline form of calcium carbonate. This relative increase in toughness value is obtained as a crack propagating within this natural brick-and-mortar structure must interact with multiple reinforcing mechanisms, leading to a millimetre-sized process zone. The boost in performance obtained has pushed scientists for a few decades to use nacre as a blueprint to increase the toughness of synthetic ceramics and composites. Our ability to reproduce accurately the structure of nacre from the nanometre to the millimetre scale has improved with the introduction of Magnetically-Assisted Slip Casting (M.A.S.C.), a technique that combines an aqueous-based slip casting process with magnetically-directed anisotropic particle assembly. Using this technique, we can now fine tune the structural properties of nacre-inspired alumina-based composites to reach strengths up to 670 MPa, KIC up to 7 MPa.m1/2 with subsequent stable crack propagation and this even at temperature up to 1200°C. While these materials already present interesting properties for engineering applications, we fail to see the large process zone that are acting in natural nacre. This led us to work on a new composite system, using this time monodisperse silica rods that can self-assemble into bulk colloidal crystals to finally test the effect of order in the microstructure on the toughness. The presence of this regularity in the microstructure proves crucial in enabling a large process zone. We obtained a 40-fold increase in toughness compared with the polymer use as a matrix in a composite made of 80% in volume of ceramic, all of which is processed at room temperature. From these two studies, we can extract the role of the interface and grain morphology in tough bioinspired composites and what will be the next steps for these materials.https://cassyni-user-files-prod.s3.amazonaws.com/FhTcpXW2zA9Hh5cTV9rtfp https://cassyni.com/events/WMLtz3f82n71yskTLEkyNu/seminar/qa https://cassyni.com/slides/outline/WMLtz3f82n71yskTLEkyNu https://cassyni.com/events/WMLtz3f82n71yskTLEkyNu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7XH9sCji3TQYrEZeDYansY https://cassyni.com/events/WMLtz3f82n71yskTLEkyNu?videoPreview=1 Inclusive Medical Design and Vascular Smooth Muscle Cell Phenotype in Tissue Engineered Blood Vesselsnohttps://cassyni.com/events/WMLtz3f82n71yskTLEkyNu?videoPreview=12025-05-27T04:00:00+00:003781.32The Auckland Bioengineering InstituteThis talk is broken into two sections. In the first section, I will focus on how passive and dynamic changes in the mechanical environment impact the differentiation of vascular smooth muscle cells (vSMCs) into a more contractile phenotype. When developing tissue engineered blood vessels that utilize vSMCs, a persistent challenge we face is that these cells retain phenotypic plasticity and will revert to a synthetic phenotype instead of the “healthy” contractile phenotype. In 2D culture, a number of biochemical and mechanical cues have been shown to promote the switch to a contractile phenotype in SMCs. However, achieving a stable contractile phenotype in 3D tissue has proven difficult. I will discuss methods that have shown promise in cell-derived vascular tissue engineered blood vessels. In the second section, I will address how centering marginalized bodies in healthcare innovation is necessary to create strategies that work for the most vulnerable in our communities. Medical devices are critical tools in modern healthcare, designed to diagnose, treat, and monitor a wide range of medical conditions. However, many of these devices are developed without fully considering the diverse needs, bodies, and experiences of marginalized populations. From blood pressure cuffs that cannot accommodate larger arms to wheelchairs that cannot navigate varied terrain, these design oversights contribute to health disparities, misdiagnosis, and substandard care for women, people of color, people with disabilities, fat individuals, queer people, and other marginalized communities. Drawing from insights developed in the context of a biomedical engineering course focused on equity and inclusion, this presentation will highlight the critical role that engineers and healthcare innovators play in addressing these gaps.https://cassyni-user-files-prod.s3.amazonaws.com/7XH9sCji3TQYrEZeDYansY https://cassyni.com/slides/outline/RQrrXDBseCZzan37Km3yem https://cassyni.com/events/RQrrXDBseCZzan37Km3yem/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JySxxrutzut1HZsLcEAD5p https://cassyni.com/events/RQrrXDBseCZzan37Km3yem?videoPreview=1 Compatible finite elements for numerical weather predictionnohttps://cassyni.com/events/RQrrXDBseCZzan37Km3yem?videoPreview=12025-10-16T12:00:00+00:002896.04MOX Laboratory - Department of MathematicsI will discuss the application of compatible finite element methods to large scale atmosphere and ocean simulation. Compatible finite element methods extend Arakawa's “C-grid” finite difference scheme to the finite element world. They are constructed from a discrete de Rham complex, which is a sequence of finite element spaces which are linked by the operators of differential calculus. The use of discrete de Rham complexes to solve partial differential equations is well established, but in this talk I focus on the specifics of dynamical cores for simulating weather, oceans and climate. The most important consequence of the discrete de Rham complex is the Hodge-Helmholtz decomposition, which has been used to exclude the possibility of several types of spurious oscillations from linear equations of geophysical flow. This means that compatible finite element spaces provide a useful framework for building dynamical cores. In this talk I will introduce the main concepts of compatible finite element spaces, and discuss their wave propagation properties. I will then cover a selection of the following topics (depending on recent advances, and interests of the audience): practical application to numerical weather prediction and ocean models, structure preserving methods, and scalable iterative solver techniques.https://cassyni-user-files-prod.s3.amazonaws.com/JySxxrutzut1HZsLcEAD5p https://cassyni.com/slides/outline/AbQj8hn8UTxNGqkQK7EF73 https://cassyni.com/events/AbQj8hn8UTxNGqkQK7EF73/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GwqQgcvkjB3zwrhMipShoU https://cassyni.com/events/AbQj8hn8UTxNGqkQK7EF73?videoPreview=1 Metascience won't solve the replication crisis: Replications across the pyramid of culture changenohttps://cassyni.com/events/AbQj8hn8UTxNGqkQK7EF73?videoPreview=12025-06-24T13:00:00+00:005301.88In this sequence of presentations, we discuss why replications - despite their high relevance - are rarely conducted and published and provide solutions that are structured around the COS's pyramid of culture change: * Replications are often not possible due to deficiencies in reporting standards and data availability. * There is no consensus on standards of replicability, leaving the door open for successful and failed replications to be dismissed as irrelevant. * There is still a lack of interest in robust research by commercial journals and funders due to an overreliance on bibliometrics in research assessment. * In sum, replication research is not rewarding unless it is based on simple studies (e.g., online surveys), reported in batches of hundreds of findings, and yields far reaching results about the replicability of research from entire fields or journals. Many metascientific studies rely on replication attempts with questionable generalizability. To support researchers in conducting replication research in a sustainable way and to provide a solid basis for meta-science on replicability in the long run, we present multiple projects from the FORRT Replication Hub that solve these problems: * Open educational resources enable future replications. * An interdisciplinary and collaborative guide to replications and reproductions will facilitate the execution of replications. * Replication rankings and journal databases allow researchers to choose journals based on robustness and openness instead of misleading bibliometrics. * A diamond open access journal will reward the publication of replication research and allow for discussions about replication methods spanning multiple disciplines.https://cassyni-user-files-prod.s3.amazonaws.com/GwqQgcvkjB3zwrhMipShoU https://cassyni.com/events/B64LBPReuvWRGcHHuYX3NM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2S4qjwVwzJruDCDAqm23Ae https://cassyni.com/events/MTheGNXZXu4ZwbGqDDQNgV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EiSbJCKDcXq7G2puVcpYb8 https://cassyni.com/slides/outline/hmUR2eZyauvEZGnC5seQd https://cassyni.com/events/hmUR2eZyauvEZGnC5seQd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5U3QBFVi1dQZTKJt7qq48W https://cassyni.com/events/hmUR2eZyauvEZGnC5seQd?videoPreview=1 Nonlinear and Electro-Optic Metal Oxides for Telecoms, Sensing & Quantum Devicesnohttps://cassyni.com/events/hmUR2eZyauvEZGnC5seQd?videoPreview=12023-05-04T12:00:00+00:002639.56UK Metamaterials NetworkThe integration of nonlinear, non-centrosymmetric metal oxides such as barium titanate and lithium niobate into miniaturized photonic devices addresses critical challenges in data transmission, sensing, and quantum technologies. These materials exhibit strong quadratic nonlinearities (χ^(2)) and electro-optic effects across a broad spectral range from near-UV to mid-IR, enabling efficient second harmonic generation, electro-optic modulation, and spontaneous parametric down conversion (SPDC) for photon pair generation. The study explores top-down fabrication of lithium niobate on insulator platforms using ion slicing, electron beam lithography, and inductively coupled plasma etching to produce submicron waveguides and Bragg gratings, achieving modulators operating at 100 Gbps with low bit error rates. Complementary thermo-optic tuning provides stable resonance control without DC drift. Challenges in etching high-aspect-ratio metasurfaces are addressed, demonstrating electro-optic modulation with low applied voltages and modulation enhancements up to 80 times compared to unstructured films. Bottom-up approaches employing nanoparticles, nanowires, and sol-gel derived polycrystalline films offer alternative routes to nonlinear photonic structures, relaxing phase-matching constraints via random quasi-phase matching and enabling SPDC in micron-scale particles and nanowires with measurable photon coincidence counts. Sol-gel nanoimprinting yields smooth, high-refractive-index films and metalenses with high aspect ratios, suitable for integrated nonlinear optics. These advances highlight the potential of metal oxide platforms for compact, efficient electro-optic and quantum photonic devices, with ongoing efforts to optimize fabrication and enhance nonlinear conversion efficiencies at the nanoscale.https://cassyni-user-files-prod.s3.amazonaws.com/5U3QBFVi1dQZTKJt7qq48W https://cassyni.com/slides/outline/E3yaa7pgx2kn8EWbASSNYm https://cassyni.com/events/E3yaa7pgx2kn8EWbASSNYm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QXQAJdWfLYF2XruF3etmG2 https://cassyni.com/events/E3yaa7pgx2kn8EWbASSNYm?videoPreview=1 Government tech stacks: Relevance in the age of AInohttps://cassyni.com/events/E3yaa7pgx2kn8EWbASSNYm?videoPreview=12025-05-21T00:00:00+00:003025.08Business SchoolThe increasing complexity of government services and the emergence of artificial intelligence necessitate robust digital infrastructure. Digital Government, beyond mere process digitization, aims to enhance service effectiveness, transparency, innovation, and trust. A critical enabler is Digital Public Infrastructure (DPI), which establishes shared digital platforms, systems, and tools to overcome siloed departmental operations and multi-tiered government structures. This approach fosters efficient and secure public service delivery across ministries, improving citizen experience and data-driven policymaking. India's implementation of its "India Stack" exemplifies a successful DPI model, built on biometric identity (Aadhaar, identifying 1.5 billion people with 100+ million daily authorizations), open data, and paperless transactions. Key outcomes include the Unified Payments Interface (UPI), processing over 7 billion monthly transactions involving 640 banks, with a cumulative value exceeding $1 trillion at zero cost to consumers. The passport program reduced issuance times from six months to four days, facilitating over 123 million documents. Further, a centralized election database managed 970 million voters, and a universal health exchange enrolled 350+ million beneficiaries across 31,000 hospitals. Such DPI initiatives demonstrably increase efficiency, accountability, and innovation, offering valuable lessons for other nations in developing citizen-centric, open, and data-driven digital ecosystems.https://cassyni-user-files-prod.s3.amazonaws.com/QXQAJdWfLYF2XruF3etmG2 https://cassyni.com/slides/outline/97VY7HMSZTDkj8oF9xjNpd https://cassyni.com/events/97VY7HMSZTDkj8oF9xjNpd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CCjJSAgHWwMvCw3QPL7tfx https://cassyni.com/events/97VY7HMSZTDkj8oF9xjNpd?videoPreview=1 Knowledge Management Adapting to the Digital (R)Evolutionnohttps://cassyni.com/events/97VY7HMSZTDkj8oF9xjNpd?videoPreview=12021-10-26T23:00:00+00:003641.56Business SchoolThis analysis explores how Knowledge Management (KM) adapts to the complexities of the digital age, characterized by the dominance of digital information (now 99.99% of all data) since 2002. The study focuses on three transformative events: the era of Big Data (emerging around 2011), the Fourth Industrial Revolution (prominent since 2016), and the accelerating impact of COVID-19. Big Data is defined by its immense volume (e.g., 1.7 megabytes created per second per human), high velocity, diverse variety (80-90% unstructured), veracity challenges, and the need for value extraction, variation analysis, and visualization. Notably, less than 0.5% of all data is analyzed. The Fourth Industrial Revolution signifies the automation of industrial practices through smart technology, blending digital, virtual, and physical worlds, and is marked by an accelerating rate of technology adoption (e.g., 50 million users gained by Pokemon Go in 19 days compared to airlines over 68 years). KM plays a crucial role in organizing this vast data, making it findable and usable. Furthermore, COVID-19 underscored KM's importance in providing real-time intelligence for sense-making, facilitating the capture of tacit knowledge, and supporting organizational risk mitigation and scenario planning. Organizations are advised to cultivate data discipline through strategic data collection, promote data democracy by decentralizing decision-making, invest in developing the right data-specific skills, and foster a culture of innovative thinking to leverage these shifts effectively.https://cassyni-user-files-prod.s3.amazonaws.com/CCjJSAgHWwMvCw3QPL7tfx https://cassyni.com/slides/outline/JVqe6uAJJWfkjMxnMf9PKs https://cassyni.com/events/JVqe6uAJJWfkjMxnMf9PKs/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Eev8tsPYs57Yr1rEyyrXeW https://cassyni.com/events/JVqe6uAJJWfkjMxnMf9PKs?videoPreview=1 Edge states in the discrete slowly-varying SSH modelnohttps://cassyni.com/events/JVqe6uAJJWfkjMxnMf9PKs?videoPreview=12025-06-16T07:00:00+00:00945.24ETOPIMThe Su-Schrieffer-Heeger (SSH) model has long served as a cornerstone in the study of topological phases of matter, offering profound insights into the emergence of edge states and their robustness against perturbations. The standard SSH model exhibits well-known topological properties: a Dirac point exists in the band structure when the inter-cell and intra-cell hopping coefficients are the same. Building on this foundation, we explore how deforming the SSH model—such as by modifying its hopping coefficients—opens the door to richer and more nuanced phenomena. In this work, we investigate deformations of the SSH model by slowly varying its inter-cell hopping parameters and uncover the precise conditions that give rise to edge states. The existence of these edge states can be quantitatively analyzed using an effective Dirac operator. For each edge state, we derive a leading-order approximation and rigorously establish its convergence rate with respect to a small parameter that characterizes the slowness of the variation in deformation. Our method of deriving the effective Dirac operator is general and can be applied to other discrete models. This is a joint work with Michael I. Weinstein.https://cassyni-user-files-prod.s3.amazonaws.com/Eev8tsPYs57Yr1rEyyrXeW https://cassyni.com/slides/outline/JzVF9aopjyDoj8Vfx6SBbB https://cassyni.com/events/JzVF9aopjyDoj8Vfx6SBbB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/YRytHUkjFY8HmBWQHMq4vr https://cassyni.com/events/JzVF9aopjyDoj8Vfx6SBbB?videoPreview=1 Models for the BRDF of disordered metasurfacesnohttps://cassyni.com/events/JzVF9aopjyDoj8Vfx6SBbB?videoPreview=12025-06-17T05:00:00+00:001598.0ETOPIMWe review our current efforts to model the bidirectional reflectance distribution function (BRDF) of disordered metasurfaces and demonstrate novel visual properties not found in biodiversity with low-index nanostructures. Introduction Disordered metasurfaces, comprising non-periodic arrangements of meta-atoms, present an untapped potential for tailoring light scattering properties [1-2]. These metasurfaces offer many degrees of freedom. Quantitatively predicting the visual appearance of metasurfaces requires advanced knowledge of the nanoscale resonances, mesoscale interferences and macroscale light transport to compute the bidirectional reflectance distribution function (BRDF). We review our current efforts to model the BRDF of disordered metasurfaces, emphasizing metasurfaces with particulate morphologies, where well-identified individual metaatoms are arranged in deterministic or random patterns. The numerical tools Approximate models are required. We have now implemented two generations of models. First generation tool. In [3], we reported the very first simulation tools to study the appearance of disordered metasurfaces. The tool predicts subtle effects not covered by earlier works on structural colors. For instance, it predicts a striking iridescence that appears when a short-range amorphous correlation is introduced in a monolayer of silver nanospheres that look grey without correlation [4], see Fig. 1 and the Supplementary Videos 1 & 2 in [3]. Second generation tool. Recently, we improved the first-generation tool and proposed an interpretive, intuitive and accurate modal-based tool that unveils the main physical mechanisms impacting the color and visual appearance of complex metasurfaces [4]. Third generation tool. In our recent work, we are developing full wave tool based on supercell approaches [4]. https://cassyni-user-files-prod.s3.amazonaws.com/YRytHUkjFY8HmBWQHMq4vr https://cassyni.com/slides/outline/VN6w7wPqxarEFdnoyCP5Gh https://cassyni.com/events/VN6w7wPqxarEFdnoyCP5Gh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VDmTV33pQ4XcDYKx4GFv7G https://cassyni.com/events/VN6w7wPqxarEFdnoyCP5Gh?videoPreview=1 Bowtie grating: wave steering in hyperbolic materialsnohttps://cassyni.com/events/VN6w7wPqxarEFdnoyCP5Gh?videoPreview=12025-06-18T03:00:00+00:001157.0ETOPIMWe present the hyperbolic analog of a bullseye grating that allows simultaneous far-field coupling of all polaritonic states with in-plane hyperbolicity. The grating can reach unity efficiency with high spectral and angular selectivity and exhibits strong field confinement and emission enhancement at its center, leading to a far-field route to polaritonic control in an all-dielectric environment. General topic. Polaritons present new degrees of freedom in tailoring light at the nanoscale through its rich dispersion assortment in natural anisotropic crystals. Of particular interest are the phonon polaritons with in-plane hyperbolicity that show high-quality propagation of deep-subwavelength directional modes on the interface of many low-symmetry Van der Waals materials. Specific aspect. To harness their supremacy over traditional diffraction-limited light, one first needs to simultaneously excite all polaritonic states lying on the hyperbolic dispersion. So far, success with linear gratings has been inherently limited because they can excite only a single state, determined by their pitch and orientation. Here, to couple far-field radiation with the entire hyperbolic branch, which is crucial for many field confinement applications and engineering of local density of states, we present a new class of surface structure that acts as the hyperbolic analog of a bullseye grating. Main results. The proposed grating gets its design blueprint from the two-dimensional inverse Fourier transform of thedispersion hyperbola, and owing to the smooth variation of local pitch and orientation, the grating transfers the correct momenta in all directions, concomitantly. A realistic implementation of the proposed grating, as shown in the Figure below, excites all hyperbolic polariton states on an alpha-phase molybdenum trioxide flake when illuminated with normally incident radiation at the design frequency. The absorption spectrum shows an almost unity coupling efficiency with a very high quality factor. The grating also exhibits strong angular selectivity in absorption and a rich anisotropic structure in its thermal emission pattern. Additionally, the grating focuses incident field at its center which leads to emission enhancement from single molecules. The proposed bowtie grating opens a new route to far-field polaritonic control in an all-dielectric environment with a broad range of potential applications, from integrated photonics to emitter design. https://cassyni-user-files-prod.s3.amazonaws.com/VDmTV33pQ4XcDYKx4GFv7G https://cassyni.com/slides/outline/RuZho9sAtNybDwVFKY17js https://cassyni.com/events/RuZho9sAtNybDwVFKY17js/abstract https://cassyni-user-files-prod.s3.amazonaws.com/89kYCSWokkCoo9X4WrapXY https://cassyni.com/events/RuZho9sAtNybDwVFKY17js?videoPreview=1 Kirchhoff's laws of thermal radiation for complex, nonreciprocal, and time-varying materialsnohttps://cassyni.com/events/RuZho9sAtNybDwVFKY17js?videoPreview=12025-06-19T23:00:00+00:00910.68ETOPIMKirchhoff’s law of thermal radiation states that the angle and frequency resolved absorptivity and emissivity of an object are equal. In recent years, metamaterials have demonstrated large control over the absorptivity and emissivity [1,2], in some cases requiring extensions of Kirchhoff’s law. For example, Kirchhoff’s law has recently been extended to structures where the emitted polarizations are correlated [3]. We verify this extension experimentally by demonstrating a direct measurement of the absorptivity and emissivity of a metasurface emitting circularly polarized light, which confirms that the emissivity is the complex conjugate of the absorptivity. Using a nonreciprocal coupled-mode theory we developed [4], we then discuss an extension of Kirchhoff’s law to nonreciprocal materials, which shows i) equivalence between absorption in an object and emission from its time-reversed counterpart and ii) that passive, nonreciprocal emitters always satisfy the second law of thermodynamics. Finally, we investigate thermal radiation from time-varying materials. We present a Kirchhoff’s law of thermal radiation, which readily enables calculation of the emmision through knowledge of the absorption, which often is much easier to obtain, and demonstrate some systems where the standard Kirchoff's law is violated in unique ways. https://cassyni-user-files-prod.s3.amazonaws.com/89kYCSWokkCoo9X4WrapXY https://cassyni.com/slides/outline/7daM5rvkeSUpStWXb6zQaH https://cassyni.com/events/7daM5rvkeSUpStWXb6zQaH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Wv8QdA1sbTBwg3wcnRKQYn https://cassyni.com/events/7daM5rvkeSUpStWXb6zQaH?videoPreview=1 Partial mycoheterotrophy: a common strategy in arbuscular mycorrhizal plants?nohttps://cassyni.com/events/7daM5rvkeSUpStWXb6zQaH?videoPreview=12025-07-10T12:00:00+00:00908.04NoneThe vast majority of land plants transfer part of the organic carbon they produce by photosynthesis to root-associated arbuscular mycorrhizal (AM) fungi, which help plants to take up nutrients and water from the soil. This carbon can be subsequently taken up by rare non-green ‘mycoheterotrophic’ plants that tap into the same fungal network. Recent findings suggest that carbon uptake from AM fungi might be a common strategy for green plants, which would qualify them as partial mycoheterotrophs or mixotrophs rather than pure autotrophs. Here, I discuss the evolutionary, ecophysiological, morphologic, genetic, and environmental evidence for the existence and prevalence of AM partial mycoheterotrophy. I conclude that there is strong, albeit indirect, evidence for the existence of AM partial mycoheterotrophy, but the taxonomic distribution of this phenomenon remains to be determined. This knowledge gap prevents us from inferring the magnitude of AM partial mycoheterotrophy in our terrestrial ecosystems and severely limits our understanding of its potential role in plant establishment and survival. https://cassyni-user-files-prod.s3.amazonaws.com/Wv8QdA1sbTBwg3wcnRKQYn https://cassyni.com/events/EYeojRz6nrEbwhW6xYZLiy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/MvyBZYpFExkucMvgC1pHL https://cassyni.com/events/B4zfqTqycDJog39HMFybZP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TG9HgaWaB66a1CSvhhGkEA https://cassyni.com/events/B4zfqTqycDJog39HMFybZP?videoPreview=1 How Will AI Impact the Future of Education and Work? Panel Discussion with the AI-ALOE Institutenohttps://cassyni.com/events/B4zfqTqycDJog39HMFybZP?videoPreview=12022-06-15T08:00:00+00:002629.88 School of Public PolicyAbstract not yet added.https://cassyni-user-files-prod.s3.amazonaws.com/TG9HgaWaB66a1CSvhhGkEA https://cassyni.com/slides/outline/96RsmMmmFk298ZfEbgBw1f https://cassyni.com/events/96RsmMmmFk298ZfEbgBw1f/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2mFU1MsyJwfLNqsoxwJe3G https://cassyni.com/events/96RsmMmmFk298ZfEbgBw1f?videoPreview=1 Gut microbiome diversity throughout animal evolutionnohttps://cassyni.com/events/96RsmMmmFk298ZfEbgBw1f?videoPreview=12026-06-02T02:00:00+00:00696.92Microbiome Virtual International Forum"Animal gut microbiomes provide key physiological functions and are critical for host health. They vary dramatically across the animal kingdom, and are shaped by factors including host diet, evolutionary history and environment. However, analyses of gut microbiomes spanning the entire metazoan clade are lacking, limiting our understanding of the fundamental principles governing gut microbiomes. Here we present the Gut Microbiome Tree of Life (GMToL), a curated 16S amplicon dataset of 17,366 samples from 1,553 host species across 26 host classes from 284 studies, enabling analysis of large-scale evolutionary trends. Using ancestral state reconstruction, we provide a critical baseline calculation of major compositional shifts in gut microbiomes throughout animal evolution. We show that the ancestral animal gut was likely dominated by Pseudomonadota. A major shift to Bacteroidota occurred during the evolution of tetrapods, followed by the emergence of Bacillota-dominated guts in mammals and birds. We identify conserved core gut microbes and demonstrate how GMToL can be leveraged to contextualize the evolutionary history of specific microbial taxa. Ultimately, this framework enables the predictive mapping of microbial symbionts across uncharacterized host lineages, and establishes a quantitative baseline for comparative microbiome research at scale."https://cassyni-user-files-prod.s3.amazonaws.com/2mFU1MsyJwfLNqsoxwJe3G https://cassyni.com/slides/outline/G1UiJJKDznqq58rdMjgbHX https://cassyni.com/events/G1UiJJKDznqq58rdMjgbHX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JhasDJyxTYgyyAzhTCuiUn https://cassyni.com/events/G1UiJJKDznqq58rdMjgbHX?videoPreview=1 Green Approaches to Sustaining the U.S. Industrial Basenohttps://cassyni.com/events/G1UiJJKDznqq58rdMjgbHX?videoPreview=12011-06-30T08:00:00+00:001244.6 School of Public PolicyNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/JhasDJyxTYgyyAzhTCuiUn https://cassyni.com/events/PuudGVhPpqZDXxerN8D4jX/seminar/qa https://cassyni.com/slides/outline/PuudGVhPpqZDXxerN8D4jX https://cassyni.com/events/PuudGVhPpqZDXxerN8D4jX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/X1oqJFVzwbDUvadnijk1Bc https://cassyni.com/events/PuudGVhPpqZDXxerN8D4jX?videoPreview=1 Global Change, Pest Invasions, and Migration: Challenges for Rural Communitiesnohttps://cassyni.com/events/PuudGVhPpqZDXxerN8D4jX?videoPreview=12025-10-17T13:00:00+00:005252.84Journal of Pest ScienceThis event covers the increasing impact of pest infestations driven by global environmental changes, with a focus on how these challenges threaten food security, disrupt migration patterns, and weaken economic resilience in rural communities. Key topics include the spread of invasive insect pests, the consequences of pest-induced crop failures, and community-based strategies and policy solutions to strengthen agricultural resilience.https://cassyni-user-files-prod.s3.amazonaws.com/X1oqJFVzwbDUvadnijk1Bc https://cassyni.com/events/JyRaofE9SG2C8rwWMeW51P/seminar/qa https://cassyni.com/slides/outline/JyRaofE9SG2C8rwWMeW51P https://cassyni.com/events/JyRaofE9SG2C8rwWMeW51P/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Y2xLLB9US1q9DpnJR8uDot https://cassyni.com/events/JyRaofE9SG2C8rwWMeW51P?videoPreview=1 REACH: Tips to Effectively Communicate Data through Graphs & Figures. nohttps://cassyni.com/events/JyRaofE9SG2C8rwWMeW51P?videoPreview=12025-12-19T18:00:00+00:003213.04Research Evaluation and Analytics Capacity Hub## This month's Casual Friday Topic: Scientific Illustrators present on tips to effectively create and communicate data through graphs/figures. Creating professional graphs to illustrate your data is important for aiding your audience's understanding. In this session, scientific illustrators Samantha Bosland and Tessa Wells will share design tips for making your graphs and graphics look more polished. They will also lead attendees through some redesign challenges to test their skills. Speaker Bios: Tessa is a science illustrator who capitalizes on the relationship between art and science and strives to assist researchers in communicating their work visually. She completed her bachelor's degrees in wildlife biology and communication arts and design with a concentration in studio arts and a minor in English at Lees-McRae College and went on to receive a graduate certificate in science illustration at California State University, Monterey Bay. She has since completed work for multiple organizations including Sylvan Heights Bird Park and the Monterey Audubon Society, reflecting her particular interest in avifauna. Samantha is a science illustrator with ten years of experience helping researchers develop the best visual communication strategies for their needs. She has worked with clients ranging from the University of Texas at Austin and Northwestern University to National Geographic and the Smithsonian Institution and previously worked at the Dallas Zoo as an exhibit graphic designer and illustrator. In our REACH Casual Friday events we aim to gather virtually with network participants, especially those participating in RAMP. The first 30-minutes will be a focused presenter and topic followed by more causal networking and possible break-out rooms.https://cassyni-user-files-prod.s3.amazonaws.com/Y2xLLB9US1q9DpnJR8uDot https://cassyni.com/slides/outline/MSdyvSwtEBrxM28pevrvsX https://cassyni.com/events/MSdyvSwtEBrxM28pevrvsX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CTxPCjMSom3bdKs1he1g4e https://cassyni.com/events/MSdyvSwtEBrxM28pevrvsX?videoPreview=1 Why is Medical School Four Years? Exploring Accelerated Three-Year MD Programsnohttps://cassyni.com/events/MSdyvSwtEBrxM28pevrvsX?videoPreview=12025-06-25T08:00:00+00:003532.0AAMCThis webinar updates the community on the current state of accelerated three-year medical programs and pathways (A3YP) in the United States. The session will introduce participants to several models of A3YP, including both small programs within traditional four-year schools as well as two models of stand-alone medical school that have embraced a three-year curriculum for their entire student body. Participants will learn about the Consortium of Accelerated Medical Pathways/Programs (CAMPP) as a group that has come together with the expressed purpose of promoting, enhancing, and evaluating the processes and outcomes related to accelerated medical training . Aggregate outcome measures of A3YP will be highlighted. Lastly, the session will describe the use of the AAMC AACOM Curriculum SCOPE Survey as a tool to help understand nationwide trends in medical education. This webinar is part of the Building Better Curriculum Series, hosted by the AAMC. For more information on the complete series, see the [series webpage](https://www.aamc.org/about-us/mission-areas/medical-education/curriculum-resources/establish-your-ci/webinars).  https://cassyni-user-files-prod.s3.amazonaws.com/CTxPCjMSom3bdKs1he1g4e https://cassyni.com/slides/outline/Hz6kbfRD9yzKKKqG1GUyLh https://cassyni.com/events/Hz6kbfRD9yzKKKqG1GUyLh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9y1eongLpr6KgAFURYe6Le https://cassyni.com/events/Hz6kbfRD9yzKKKqG1GUyLh?videoPreview=1 On the Evolution of "Postphenomenology" as a School of Thoughtnohttps://cassyni.com/events/Hz6kbfRD9yzKKKqG1GUyLh?videoPreview=12023-04-05T08:00:00+00:004530.24 School of Public PolicyThis seminar examines the evolution and current trajectories of postphenomenology as a distinctive school of thought within the philosophy of technology. Postphenomenology, originally coined by Don Ihde, is characterized by its pragmatist-oriented, non-foundational approach to understanding human-technology relations, emphasizing technological mediation as a core concept. The analysis foregrounds Ihde’s influential quartet of human-technology relations—embodiment, hermeneutic, alterity, and background relations—and explores subsequent expansions by scholars such as Peter-Paul Verbeek, who introduced notions like cyborg relations and immersion. Central to postphenomenology is the co-constitution of users and their worlds through technology, highlighting a relational ontology where both are mutually transformed. The concept of multi-stability is advanced to capture the multiplicity of technological uses and meanings across contexts, resisting simplistic instrumentalist or determinist accounts. Empirical examples, including scientific imaging debates and the cultural reception of robotic seals in elder care, illustrate these ideas. The seminar also addresses the political dimensions of technology, particularly through the critique of hostile architecture—design features in public spaces that restrict homeless individuals’ use—linking postphenomenological insights with feminist epistemology and critical theory to analyze how technologies sediment perceptual and moral frameworks. The speaker’s interdisciplinary work, spanning cognitive science and public advocacy, demonstrates the practical implications of postphenomenology for ethical reflection, policy discourse, and design practices, while acknowledging ongoing conceptual challenges and the need for nuanced political engagement.https://cassyni-user-files-prod.s3.amazonaws.com/9y1eongLpr6KgAFURYe6Le https://cassyni.com/slides/outline/LTLmq5eqMGkogGJpYxPc4d https://cassyni.com/events/LTLmq5eqMGkogGJpYxPc4d/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WBBtEzcSq4cbXckRRTF1Fc https://cassyni.com/events/LTLmq5eqMGkogGJpYxPc4d?videoPreview=1 Evaluating the Impacts of Federal Research Investmentsnohttps://cassyni.com/events/LTLmq5eqMGkogGJpYxPc4d?videoPreview=12011-09-25T08:00:00+00:00566.68 School of Public PolicyThe cumulative and networked nature of scientific knowledge complicates the assessment of federal research investments, particularly those by the Department of Energy’s Office of Science. This study addresses the challenge by analyzing patent citation data to trace the impact of Office of Science–funded research on emerging technologies. Focusing on patents issued between 1995 and 1999 and their citations in 2001–2002, the analysis identifies a “hotspot” comprising the top 2% of high-impact patents that significantly influence current technological developments. Office of Science–associated patents—defined as those directly funded or citing Office of Science–funded research—are found to be overrepresented in this hotspot, accounting for 5% of such patents, surpassing the 4% representation of Stanford University patents. Co-citation clustering of 16,000 hotspot patents reveals 423 thematic clusters, which are further categorized into seven broad technological areas including biotechnology, advanced materials, and electronics. The Office of Science supports 23 of these clusters, underpinning innovations such as carbon dioxide cleaning, digital security, and microfluidics. A detailed case study highlights the development of a cost-effective short-range radar technology originating from Lawrence Livermore National Laboratory, which led to diverse commercial applications. Overall, the findings demonstrate that Office of Science research contributes disproportionately to high-impact emerging technologies, indicating a substantial return on public investment and providing a robust metric for evaluating federal research impact across the U.S. technological landscape.https://cassyni-user-files-prod.s3.amazonaws.com/WBBtEzcSq4cbXckRRTF1Fc https://cassyni.com/slides/outline/UrN3chekp4AnqbfHcoifHX https://cassyni.com/events/UrN3chekp4AnqbfHcoifHX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/SE9AozjUygKCnAqMvufr7G https://cassyni.com/events/UrN3chekp4AnqbfHcoifHX?videoPreview=1 The Social Impacts of Drug Use and Substance-Use Disordernohttps://cassyni.com/events/UrN3chekp4AnqbfHcoifHX?videoPreview=12021-10-14T08:00:00+00:003559.72 School of Public PolicyThis seminar addresses the multifaceted social impacts of drug use and substance-use disorders through three focused analyses. The first study examines the effects of medication-assisted opioid treatment programs on child well-being in Indiana, leveraging a natural experiment created by a gubernatorial policy shift that lifted a moratorium on such programs. Using county-level comparisons and fixed effects models, findings indicate a 39% reduction in opioid-related emergency department visits and a 22% decrease in out-of-home foster care placements following program implementation, with a suggested 7% decline in physical abuse reports but no significant changes in neglect or sexual abuse rates. The second analysis investigates substance use among low-income households during the COVID-19 pandemic, utilizing panel survey data from the Understanding America Study. Employing two-way fixed effects models, results reveal that job loss alone did not significantly increase substance use; however, receipt of unemployment insurance (UI) benefits among the unemployed was associated with reduced consumption of cannabis, recreational drugs, and alcohol, though not smoking. Contrarily, stimulus checks and TANF benefits correlated with increased substance use, suggesting complex interactions between social safety nets and substance use behaviors. The third presentation explores youth protection amid expanding state marijuana legalization. Drawing on comparative policy analysis and literature from tobacco and alcohol regulation, it highlights increased adolescent marijuana initiation and use in legalized states, emphasizing the need for stringent regulations on product composition, packaging, advertising, retail access, and allocation of tax revenues toward prevention. The analysis underscores gaps in current state policies, particularly regarding flavored products, social media advertising, and youth exposure, advocating for research-based safeguards to mitigate adverse youth outcomes. Collectively, these studies underscore the critical role of targeted policies and social supports in mitigating the social harms of substance use, particularly among vulnerable populations such as children and low-income families, and emphasize the importance of protective measures in the context of drug law liberalization.https://cassyni-user-files-prod.s3.amazonaws.com/SE9AozjUygKCnAqMvufr7G https://cassyni.com/slides/outline/XKc4r7tP1LwHCY8rAVdJ1T https://cassyni.com/events/XKc4r7tP1LwHCY8rAVdJ1T/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Lo1XJUci9eDiJKj865eVbL https://cassyni.com/events/XKc4r7tP1LwHCY8rAVdJ1T?videoPreview=1 Geeks, Robots, and Grand Challenges: Prototyping Collective Identity within an Emerging AV Fieldnohttps://cassyni.com/events/XKc4r7tP1LwHCY8rAVdJ1T?videoPreview=12023-12-18T09:00:00+00:002525.12 School of Public PolicyThis study examines the formation of collective identity within the emerging field of autonomous vehicles (AVs), focusing on the role of the DARPA Grand Challenges as a catalyst for technological and social innovation. The analysis draws on extensive qualitative data, including 157 interviews with participants from 47 of the 52 qualifying teams across the three DARPA races held between 2004 and 2007, as well as archival materials such as DARPA’s internal documentation. The investigation reveals that while major institutions like Stanford and Carnegie Mellon dominated in resources and systems integration, numerous smaller teams—often composed of hobbyists and volunteers with limited prior robotics experience—contributed significant component-level innovations, such as novel sensors and algorithms. These contributions were driven not solely by funding but by cultural entrepreneurship and shared identity formation around the prototype robots and the collective challenge. The interaction between teams and their evolving robotic platforms fostered a co-evolutionary process of identity development, where material artifacts (robots) played a central role in shaping participants’ sense of belonging and purpose within the nascent AV field. The findings highlight the importance of social capital, iterative prototyping, and meaning-making in technological ecosystems, suggesting that innovation policy should consider identity and community dynamics alongside financial resources. This work advances understanding of how grand challenge competitions can serve as social laboratories for field emergence, with implications for designing future innovation initiatives that integrate technological and cultural dimensions.https://cassyni-user-files-prod.s3.amazonaws.com/Lo1XJUci9eDiJKj865eVbL https://cassyni.com/events/RtW3TEHVafmydfw5j651A5/seminar/qa https://cassyni.com/slides/outline/RtW3TEHVafmydfw5j651A5 https://cassyni.com/events/RtW3TEHVafmydfw5j651A5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/N5bdBSSizAjd93XayMe2KY https://cassyni.com/events/RtW3TEHVafmydfw5j651A5?videoPreview=1 A spectacular recovery: Feral cats and fox exclusion dramatically reshapes a small mammal community in an Australian desertnohttps://cassyni.com/events/RtW3TEHVafmydfw5j651A5?videoPreview=12025-11-05T08:00:00+00:003490.88Royal Society PublishingInvasive species can alter small mammal communities. We examined the abundance and demography of 10 Australian desert small mammals inside and outside a fenced reserve after the exclusion of invasive rabbits, cats and foxes. Over 26 years, we found evidence for a species succession response triggered by the removal of endogenous disturbance (predation), similar to exogenous disturbance caused by fire, mining and deglaciation. Smaller rodents responded within 2 years whereas larger rodents became more abundant within the reserve after 5 years, eventually outcompeting the smaller rodents. The dasyurid response was later and more muted. Captures of rodents inside the reserve reached up to 33 times higher than outside after high rainfall years, suggesting that invasive predators have a significant impact and suppress rainfall-induced population booms. Larger rodents expanded their realized niche into non-preferred habitats, and intraspecific competition and species diversity increased. Minimal differences in breeding, body mass or sex ratios between inside and outside the reserve suggested abundance increases were primarily due to release from predation pressure rather than increased resources. Succession was shaped by competition and differences in predator susceptibility influencing reinvasion timing. Results demonstrate that succession dynamics in small mammals can be triggered by the removal of endogenous disturbance as well as changes in vegetation structure.https://cassyni-user-files-prod.s3.amazonaws.com/N5bdBSSizAjd93XayMe2KY https://cassyni.com/slides/outline/Ts4qXLMhw94eAqqHWqFLUd https://cassyni.com/events/Ts4qXLMhw94eAqqHWqFLUd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FV9m9KkZPwVBRzHsbMX5iN https://cassyni.com/events/Ts4qXLMhw94eAqqHWqFLUd?videoPreview=1 AI Applications and Freedom of Expressionnohttps://cassyni.com/events/Ts4qXLMhw94eAqqHWqFLUd?videoPreview=12024-10-18T08:00:00+00:004704.88 School of Public PolicyThis seminar addresses the multifaceted challenges and realities of artificial intelligence (AI) applications in disinformation and freedom of expression, integrating empirical research, legal analysis, and technical evaluation. An empirical study of disinformation during the Zaporizhzhia and Fukushima nuclear emergencies reveals limited evidence of state actors employing generative AI for disinformation creation. Instead, traditional state-owned media remain primary disseminators, leveraging established credibility and socio-cultural contexts that significantly influence public reception and resilience to false narratives. The study highlights AI’s current limitations in contextual understanding and rapid adaptation to evolving geopolitical narratives, underscoring the necessity of continuous human intervention. Complementing this, legal analysis of recent U.S. Supreme Court cases (notably Moody v. NetChoice) explores the constitutional protections afforded to social media platforms’ editorial rights in content moderation via algorithms and AI tools. The Court affirms that algorithmic implementation of human editorial standards generally merits First Amendment protection, though concerns persist regarding autonomous AI decision-making and transparency of “secret algorithms.” Divergent judicial views emphasize the need for granular fact-finding on algorithmic functions before extending constitutional safeguards. From a technical perspective, evaluation of large language models (LLMs) reveals persistent cultural biases and context insensitivity, with models disproportionately associating non-Western names with negative stereotypes and exhibiting uneven performance across cultural contexts. The discussion advocates for improved, safety-focused benchmarks and red-teaming methodologies to address implicit harms and enhance model fairness. Overall, the seminar underscores that while AI poses potential risks in disinformation and content moderation, human judgment, institutional trust, and socio-cultural factors remain paramount, and that governance approaches must balance technological capabilities with transparency, accountability, and pluralistic values.https://cassyni-user-files-prod.s3.amazonaws.com/FV9m9KkZPwVBRzHsbMX5iN https://cassyni.com/slides/outline/6dBrXwY94TFL35r7eH3CKo https://cassyni.com/events/6dBrXwY94TFL35r7eH3CKo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/SnvvmreB2XxoS8NtcavhxJ https://cassyni.com/events/6dBrXwY94TFL35r7eH3CKo?videoPreview=1 Ethics & Values for Reflective Urban Automationnohttps://cassyni.com/events/6dBrXwY94TFL35r7eH3CKo?videoPreview=12019-01-24T09:00:00+00:003742.6 School of Public PolicyThis seminar addresses the ethical and value-based challenges emerging from urban automation, focusing on autonomous vehicles, data-driven urbanism, and inclusive design within smart cities. The discussion foregrounds three scales of ethical concern related to autonomous vehicles: individual vehicle dilemmas (e.g., safety, privacy, pedestrian interaction), interactions among vehicles with varying automation levels, and systemic urban impacts such as infrastructure redesign and social justice implications. The analysis highlights privacy risks inherent in pervasive urban data collection, emphasizing breaches of bodily, territorial, locational, communicational, and transactional privacy, and critiques the assumption of data neutrality by revealing how datafication shapes urban governance and social sorting. The role of public and private sectors in managing data ethics is underscored, with calls for transparency, informed consent, and equitable benefit sharing. Economic and labor implications are examined through the lens of e-commerce-driven automation in metropolitan supply chains, revealing precarious work conditions and the need for ethical frameworks that uphold human rights to just employment amid technological restructuring. The integration of digital and physical environments in intelligent buildings introduces further ethical considerations regarding data ownership, surveillance, and user autonomy. Accessibility and inclusion emerge as critical ethical imperatives, particularly for people with disabilities, stressing universal design principles, equitable participation in technology development, and the necessity of ethical frameworks that address privacy, safety, and usability. The seminar concludes that ethical reflection must continuously inform legal standards and design practices to ensure urban automation advances social justice, inclusivity, and human dignity.https://cassyni-user-files-prod.s3.amazonaws.com/SnvvmreB2XxoS8NtcavhxJ https://cassyni.com/slides/outline/GW9wTcUdqcKetbr99qoZTj https://cassyni.com/events/GW9wTcUdqcKetbr99qoZTj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/MtX1iC4wcSwKtu4unvrub4 https://cassyni.com/events/GW9wTcUdqcKetbr99qoZTj?videoPreview=1 UKAEA’s fusion energy strategynohttps://cassyni.com/events/GW9wTcUdqcKetbr99qoZTj?videoPreview=12023-05-04T06:00:00+00:002639.0Journal of Plasma PhysicsThis talk will begin by explaining the UK government strategy to delivering fusion and setting this in the context of other major fusion programmes internationally. We will explore the new facilities and programmes being pursued at UKAEA, including an overview of the progress made on the prototype powerplant STEP – the Spherical Tokamak for Energy Production. Finally, the talk will explore the relationships between the public and private sector that will be important in the delivery of fusion power.https://cassyni-user-files-prod.s3.amazonaws.com/MtX1iC4wcSwKtu4unvrub4 https://cassyni.com/events/UMk4geX7mxYTzcQeGmydt1/seminar/qa https://cassyni.com/slides/outline/UMk4geX7mxYTzcQeGmydt1 https://cassyni.com/events/UMk4geX7mxYTzcQeGmydt1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WJRbVeeDHnuCxpMftsZLii https://cassyni.com/events/UMk4geX7mxYTzcQeGmydt1?videoPreview=1 Women’s Health Issues Across Arab Societies: Contexts, Challenges, and Opportunities for Changenohttps://cassyni.com/events/UMk4geX7mxYTzcQeGmydt1?videoPreview=12026-01-20T11:00:00+00:003550.56Women's Health“Every challenge to women’s health is also an opportunity for empowerment and transformation.” - Prof. Haleama Al Sabbah, Guest Editor of the Special Collectionhttps://cassyni-user-files-prod.s3.amazonaws.com/WJRbVeeDHnuCxpMftsZLii https://cassyni.com/events/BZftzn1PT2ndVW8o9N6Zjb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2ujiq93JSMStZq2ZKR3qL2 https://cassyni.com/events/VM3Gn1pAesecfNEeNkSxgu/seminar/qa https://cassyni.com/slides/outline/VM3Gn1pAesecfNEeNkSxgu https://cassyni.com/events/VM3Gn1pAesecfNEeNkSxgu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HyjjAsCxjpB37jKgaaV2HC https://cassyni.com/events/VM3Gn1pAesecfNEeNkSxgu?videoPreview=1 Autoencoders latent space interpretability in the light of proper orthogonal decompositionnohttps://cassyni.com/events/VM3Gn1pAesecfNEeNkSxgu?videoPreview=12025-11-17T14:00:00+00:002970.6Computer Physics CommunicationsWe study how Autoencoders (AEs) and Variational Autoencoders (VAEs) learn and represent dynamic velocity fields from periodically forced Navier–Stokes flows. We compare reconstruction accuracy, regularization effects, and training behaviors, linking latent spaces to POD modes and flow symmetries. Despite lower accuracy, VAEs better preserve physical equivariances. A clustering-based analysis further clarifies latent structures, enabling the localization of POD modes within the latent space.https://cassyni-user-files-prod.s3.amazonaws.com/HyjjAsCxjpB37jKgaaV2HC https://cassyni.com/slides/outline/49yTR9pQGXQZpveoLzgLTf https://cassyni.com/events/49yTR9pQGXQZpveoLzgLTf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VGyq2Vdyp1iB5Nne9QE6fQ https://cassyni.com/events/49yTR9pQGXQZpveoLzgLTf?videoPreview=1 LIFD – 5 years of fluids and looking to the futurenohttps://cassyni.com/events/49yTR9pQGXQZpveoLzgLTf?videoPreview=12024-01-25T06:00:00+00:001611.96Leeds Institute for Fluid DynamicsNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/VGyq2Vdyp1iB5Nne9QE6fQ https://cassyni.com/slides/outline/59GfWX7T9SWiVgUoSy9fGZ https://cassyni.com/events/59GfWX7T9SWiVgUoSy9fGZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8FKwzDzhwziCJCp8XCCJpn https://cassyni.com/events/59GfWX7T9SWiVgUoSy9fGZ?videoPreview=1 Monitoring Our Health With Smartwatchesnohttps://cassyni.com/events/59GfWX7T9SWiVgUoSy9fGZ?videoPreview=12021-05-26T06:00:00+00:003533.12Part of the nonprofit Annual Reviews organizationOnce geared toward fitness enthusiasts, Fitbits, Apple Watches and other wearable sensors are gaining a foothold in the medical realm. Whether keeping an eye on the heart, tracking seizures or glucose levels, or surveying for viral infections, the devices hold promise as a way to gather valuable information that could guide health-related decisions. But how much can they tell you? How reliable are they? And how do you bridge the gap between just wearing a sensor and taking action — from going to the ER to making longer-term lifestyle changes? Join us for a discussion with two leading experts on the promise and pitfalls of the technologies that may already be on a wrist near you.https://cassyni-user-files-prod.s3.amazonaws.com/8FKwzDzhwziCJCp8XCCJpn https://cassyni.com/events/7cWgjwM5LjHCrcxMzf4HzV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2CaavhztHSxm3PkGz3NKNE https://cassyni.com/slides/outline/EXb9PWQRV92zMRwwN6dE9B https://cassyni.com/events/EXb9PWQRV92zMRwwN6dE9B/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5B9RPUX5imLXKvBaxx1ksp https://cassyni.com/events/EXb9PWQRV92zMRwwN6dE9B?videoPreview=1 Reconstructions of electron-temperature profiles from EUROfusion Pedestal Database using turbulence models and machine learningnohttps://cassyni.com/events/EXb9PWQRV92zMRwwN6dE9B?videoPreview=12025-10-09T15:00:00+00:002657.8Journal of Plasma PhysicsIn magnetic confinement devices, the H-mode results in improved confinement and is therefore a desirable regime for future tokamaks. We focus on the anomalous heat transport governed by large electron-temperature and density gradients in the H-mode pedestals of JET-ILW. Using the EUROfusion Pedestal Database, we apply machine-learning (ML) methods to identify a hierarchy of the most important experimental parameters for reconstructing the electron-temperature pedestal. The success of our ML reconstructions suggests that the dataset is sufficiently large for statistically meaningful inference, and we recover a potential upper bound on the accuracy achievable with data-driven models. We then employ a physically informed model based on the electron-gradient ratio $\eta_e = L_{n_e} / L_{T_e}$ (a parameter relevant to the slab-ETG instability) and reconstruct pedestals using the experimental observation that $\eta_e \approx 2$ in much of the steep-gradient region. Another tested scaling law, $R/L_{T_e} = A (R/L_{n_e})^\alpha$, reveals a collapse of $A$ and $\alpha$ to a one-parameter family, enabling a compact empirical description of both JET-ILW and JET-C pedestals; the origin of this constraint remains unclear but may be linked to turbulent transport. Finally, we introduce the turbulent electron heat flux as a predictive parameter and test the accuracy of transport models inspired by nonlinear gyrokinetic simulations. Although these models vastly improve our previous analytic-modelling attempts, they underperform relative to ML methods; nevertheless, they offer a qualitative picture of the features required for turbulence models to represent the data and provide a foundation for future model validation against this database.https://cassyni-user-files-prod.s3.amazonaws.com/5B9RPUX5imLXKvBaxx1ksp https://cassyni.com/events/9b76vfwB6ZVxxLEbMcvER3/seminar/qa https://cassyni.com/slides/outline/9b76vfwB6ZVxxLEbMcvER3 https://cassyni.com/events/9b76vfwB6ZVxxLEbMcvER3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TyHwqPXoNfHQXZQpqbjKt https://cassyni.com/events/9b76vfwB6ZVxxLEbMcvER3?videoPreview=1 Acoustic wave diffraction by a quadrant of sound-soft scatterersnohttps://cassyni.com/events/9b76vfwB6ZVxxLEbMcvER3?videoPreview=12025-10-28T14:00:00+00:003379.04MetaMATMotivated by research in metamaterials, we consider the challenging problem of acoustic wave scattering by a doubly periodic quadrant of sound-soft scatterers arranged in a square formation, which we have dubbed the quarter lattice. We consider two approaches using the Wiener-Hopf technique that differ by how the quarter lattice is decomposed. The first approach views the lattice as a set of separate rows/columns and leads to a series of uncoupled and simple Wiener-Hopf problems, The second focuses on the nearest neighbourhood interactions and leads to a Wiener-Hopf equation in two complex variables with three unknown functions for which we can reduce and solve exactly using a new analytic method. After some suitable truncations, the resulting linear system is inverted using elementary matrix arithmetic and the solution can be numerically computed. This solution is also critically compared to a numerical least squares collocation approach and to our previous method where we decomposed the lattice into semi-infinite rows or columns.https://cassyni-user-files-prod.s3.amazonaws.com/TyHwqPXoNfHQXZQpqbjKt https://cassyni.com/events/GzrnjZ9w5njXbPTTc4iQTf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GiKkFjR9b56H4Mcb2gDbq8 https://cassyni.com/slides/outline/QQarRoroff33MReNAEL2uj https://cassyni.com/events/QQarRoroff33MReNAEL2uj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4EUkQcP9MEoSHb2RgZPzKx https://cassyni.com/events/QQarRoroff33MReNAEL2uj?videoPreview=1 Genetic and ecological determinants of bacterial pathogen success during plant infectionnohttps://cassyni.com/events/QQarRoroff33MReNAEL2uj?videoPreview=12025-08-04T14:15:00+00:006386.68NoneCrop pathogens significantly reduce agricultural production. Early interactions between the pathogen and its environment in the host determine whether the pathogen can establish and cause disease. Here, we used functional genomics approaches (RNAseq & RB-TnSeq) to identify *Xanthomonas campestris* genes involved in early colonization of the plant leaf. We found that metabolic capacities, transport, defense evasion, and stress tolerance functions contribute to bacterial growth in the host. Interestingly, we also found that cooperation and cheating for virulence functions occurred among TnSeq mutant strains. This prompted us to investigate how the social behaviors of pathogens could shape infection outcomes. We focused on phenotypic heterogeneity within a clonal pathogen population. We asked how local interactions between individual pathogen cells and their environment affect the co-existence of phenotypically diverse subpopulations. Using computational simulations of plant infection, we identified conditions (spatial arrangement, initial abundances, plant and microbial traits) that restrict pathogen colonization. In particular, we found that bottlenecks in the plant tissue restrict co-existence and limit bacterial spreading. On the other hand, quick restoration of phenotypic heterogeneity after bottlenecks promotes division of labor for immunosuppression and ensures tissue colonization. Altogether, this research helps elucidate the strategies of plant pathogens in their natural ecological context.https://cassyni-user-files-prod.s3.amazonaws.com/4EUkQcP9MEoSHb2RgZPzKx https://cassyni.com/events/XpJv84ZgFXLsr1Aq87BmKj/abstract https://cassyni.com/slides/outline/SPBGcYSuRVFoT8vbXCByLH https://cassyni.com/events/SPBGcYSuRVFoT8vbXCByLH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/URdKg9YjkcGWCSBcaZtwWW https://cassyni.com/events/SPBGcYSuRVFoT8vbXCByLH?videoPreview=1 From Access to Inclusion: Tackling Systemic Barriers in Global Scholarly Publishingnohttps://cassyni.com/events/SPBGcYSuRVFoT8vbXCByLH?videoPreview=12026-01-13T14:30:00+00:004533.0Academic Publishing in EuropeOpen access is removing paywalls for readers, yet inequities in scholarly publishing remain. Editorial bias, language dominance, and the underrepresentation of scholars from the Global South on editorial boards continue to shape which voices and topics are visible in the global record. Financial practices also present barriers: waivers and discounts can be cumbersome, and engagement with Global South consortia in open access agreements is still limited. Improving equity means exploring new approaches — in both editorial and financial practices — that expand participation and strengthen scholarly publishing as a truly global, inclusive system.https://cassyni-user-files-prod.s3.amazonaws.com/URdKg9YjkcGWCSBcaZtwWW https://cassyni.com/slides/outline/SspsfE6RrworSuTV7dUmbb https://cassyni.com/events/SspsfE6RrworSuTV7dUmbb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4ELDaAEdh9SrjHSVRsDkvJ https://cassyni.com/events/SspsfE6RrworSuTV7dUmbb?videoPreview=1 Beyond the Journal Article: Exploring alternative scholarly publication formatsnohttps://cassyni.com/events/SspsfE6RrworSuTV7dUmbb?videoPreview=12026-02-25T12:30:00+00:001761.12Researcher to ReaderThis presentation examines researchers´ perception of scholarly publications beyond traditional journal articles, exploring “novel” types of publication such as data publications, software, and replication studies as well as publication types used for science-to-public communication. Drawing on survey findings from 600+ researchers and broader international trends, we analyse characteristics of scholarly publications and developments in the recognition of emerging publication formats. The presentation provides insights for publishers developing business models, librarians supporting and cataloguing diverse research outputs, as well as funders and policy makers involved in the current debates on advancing research assessment.https://cassyni-user-files-prod.s3.amazonaws.com/4ELDaAEdh9SrjHSVRsDkvJ https://cassyni.com/events/E2c4yGaGDMNAvQiATua4ny/seminar/qa https://cassyni.com/slides/outline/E2c4yGaGDMNAvQiATua4ny https://cassyni.com/events/E2c4yGaGDMNAvQiATua4ny/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5cA1ASXk3dX5JQLHTJkzTp https://cassyni.com/events/E2c4yGaGDMNAvQiATua4ny?videoPreview=1 Unravelling Collagen’s Metastabilitynohttps://cassyni.com/events/E2c4yGaGDMNAvQiATua4ny?videoPreview=12026-02-19T15:00:00+00:004890.88Journal of Biological PhysicsCollagen has been evolutionarily selected as the preferred building block of extracellular structures, where it constitutes approximately 20% of the body’s protein mass. Despite the inherent and surprising thermodynamic instability of individual proteins at body temperature, collagen manages to assemble into higher-order structures that provide mechanical support to tissues and are widely used as scaffolds for tissue engineering. Our studies are aimed at understanding how chemical composition, environment and mechanical force influence the thermal metastability of collagen proteins. In this talk, I will describe how we are using the techniques of atomic force microscopy and centrifuge force microscopy to study collagen’s mechanics and stability, one molecule at a time. Our work is revealing clues as to how stability is encoded within collagen’s sequence, and how collagen’s triple helix balances structural stability with responsiveness to applied force and its chemical and thermal environment.https://cassyni-user-files-prod.s3.amazonaws.com/5cA1ASXk3dX5JQLHTJkzTp https://cassyni.com/events/GVr6CgotQe8fHMBj1bUhWu/seminar/qa https://cassyni.com/slides/outline/GVr6CgotQe8fHMBj1bUhWu https://cassyni.com/events/GVr6CgotQe8fHMBj1bUhWu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BMoQyU2ivodMMnWLNRHCSA https://cassyni.com/events/GVr6CgotQe8fHMBj1bUhWu?videoPreview=1 Large-Deformation Aeroelasticity: Insights from the Pazy Wing Familynohttps://cassyni.com/events/GVr6CgotQe8fHMBj1bUhWu?videoPreview=12026-03-17T14:00:00+00:003535.8AIAA JournalModern high-aspect-ratio wings may operate in regimes where geometric nonlinearities impact their aeroelastic response, even under nominal flight conditions. In such configurations, classical linear models fail to capture key phenomena such as large static deformations, deformation-dependent mode shapes, and variations in flutter mechanism and onset speed. This talk presents a unified view of large-deformation aeroelasticity through a combination of wind-tunnel experiments and nonlinear modeling, centered on the Pazy wing benchmark—a very flexible wing capable of deflecting up to 50% of its span under aerodynamic loading. An experimental campaign produced an openly available dataset of static and dynamic aeroelastic response, including deformation, modal characteristics, flutter, and limit-cycle oscillation behavior. These data reveal deformation-induced changes in structural dynamics, including a reduction of torsional frequencies and the emergence of hump-type flutter that stabilizes again at higher speeds. To interpret and predict these behaviors, a nonlinear aeroelastic framework based on the Modal Rotation Method is employed, enabling large-deformation analysis using linear modal data. Building on the straight-wing benchmark, the talk extends the discussion to swept flexible wings, exploring the combined impact of sweep-induced aerodynamics, bending–torsion coupling, and wing deformation on flutter mechanism and characteristics. The presentation concludes with key physical insights, modeling lessons, and open challenges for predicting flutter, post-flutter, and limit-cycle oscillations in the next generation of very-flexible wings. https://cassyni-user-files-prod.s3.amazonaws.com/BMoQyU2ivodMMnWLNRHCSA https://cassyni.com/slides/outline/D3fxN5yja8JNoiznCx8Mrm https://cassyni.com/events/D3fxN5yja8JNoiznCx8Mrm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5oCj5W7rt5Zry1Wzay31Bk https://cassyni.com/events/D3fxN5yja8JNoiznCx8Mrm?videoPreview=1 AI for Efficiency and Automationnohttps://cassyni.com/events/D3fxN5yja8JNoiznCx8Mrm?videoPreview=12025-08-21T06:00:00+00:003529.96AAMCThis webinar explored how AI can reduce busywork and streamline tasks in education, research, and healthcare operations. Participants learned to automate scheduling, document summarization, and data organization. The session also addressed the effectiveness and ethical implications of AI-driven automation in medical education. Objectives: - Identify AI tools that can streamline tasks in medical education - Automate repetitive processes using AI - Evaluate the effectiveness and ethical implications of AI-driven automation in education This webinar is part of the AI Skill Building for Medical Educators Webinar Series, hosted by the AAMC. For more information, see [the complete series webpage](https://www.aamc.org/learn-network/affinity-groups/group-educational-affairs/webinar-series-ai-skill-building-medical-educators).   CME Information - View the last page of the slide deck for complete instructions on earning CME credit for this recording - CME credit for this learning opportunity is organized by Michigan State University College of Human Medicine Office of Continuing Medical Education - You will be prompted to create an account to obtain credithttps://cassyni-user-files-prod.s3.amazonaws.com/5oCj5W7rt5Zry1Wzay31Bk https://cassyni.com/slides/outline/FWuybWDMmR4sAfULke2zah https://cassyni.com/events/FWuybWDMmR4sAfULke2zah/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5eGohpb9gBGFM2tsVTR5Ae https://cassyni.com/events/FWuybWDMmR4sAfULke2zah?videoPreview=1 JWPE 3-min Pitch 2025: "My Life in Water" - Part 2nohttps://cassyni.com/events/FWuybWDMmR4sAfULke2zah?videoPreview=12025-12-02T13:00:00+00:002123.12ElsevierThe JWPE 3-Minute Pitch - 'My Life in Water' is a global initiative that celebrates the outstanding research conducted by PhD students from any country working in the area of water processing and engineering. It aims at supporting dissemination and outreach training to develop capacity building for JWPE’s outcoming and emerging researchers. The challenge is for PhD students to encapsulate their research in a three-minute presentation, using language understandable to a non-specialist audience.https://cassyni-user-files-prod.s3.amazonaws.com/5eGohpb9gBGFM2tsVTR5Ae https://cassyni.com/events/NS24MhnbKBkNoxAKQeYNN1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VpRv17KUVfkiM6JdaiNJAz https://cassyni.com/events/NvffQPS7keJRoihD15qAdK/seminar/qa https://cassyni.com/events/NvffQPS7keJRoihD15qAdK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JPr4AuFSaUvz53rke5EmN6 https://cassyni.com/slides/outline/HVY1tsKLvcDMQrSyQAqNds https://cassyni.com/events/HVY1tsKLvcDMQrSyQAqNds/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6YB8eXb9YGQ49iDtGNhXHQ https://cassyni.com/events/HVY1tsKLvcDMQrSyQAqNds?videoPreview=1 Personalizing Learning with AInohttps://cassyni.com/events/HVY1tsKLvcDMQrSyQAqNds?videoPreview=12025-11-20T14:00:00+00:003597.84AAMCObjectives: - Develop personalized learning activities using AI tools. - Explore AI applications for virtual simulations and intelligent tutoring. - Assess the effectiveness of AI-driven personalized learning solutions. This webinar is part of the AI Skill Building for Medical Educators Webinar Series, hosted by the AAMC. For more information, see [the complete series webpage](https://www.aamc.org/learn-network/affinity-groups/group-educational-affairs/webinar-series-ai-skill-building-medical-educators).   CME Information - View the last page of the slide deck for complete instructions on earning CME credit for this recording - CME credit for this learning opportunity is organized by Michigan State University College of Human Medicine Office of Continuing Medical Education - You will be prompted to create an account to obtain credithttps://cassyni-user-files-prod.s3.amazonaws.com/6YB8eXb9YGQ49iDtGNhXHQ https://cassyni.com/events/Pubn1a2ePsNDvQQbG3GsZX/seminar/qa https://cassyni.com/slides/outline/Pubn1a2ePsNDvQQbG3GsZX https://cassyni.com/events/Pubn1a2ePsNDvQQbG3GsZX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QiczxqSMMbbuHjAfdqKL3p https://cassyni.com/events/Pubn1a2ePsNDvQQbG3GsZX?videoPreview=1 GPU-accelerated level-set DEM for modeling arbitrarily shaped particles and its MPM couplingnohttps://cassyni.com/events/Pubn1a2ePsNDvQQbG3GsZX?videoPreview=12026-03-24T13:00:00+00:004086.92Granular MatterEfficiently simulating interactions among large-scale discrete particles with irregular shapes remains a significant challenge in computational modeling of granular systems. This webinar introduces a high-performance, GPU-optimized framework for the level-set discrete element method (DEM), designed to handle arbitrarily shaped particles with exceptional efficiency. We will present an enhanced computational approach that includes an extended multilevel linked-cell method, featuring a two-layer Verlet table to manage polydisperse irregular particle systems. To ensure robust contact resolution, the framework implements an energy-conserving contact model. Additionally, a shape template strategy is employed to significantly reduce memory consumption. The session will showcase several numerical examples that demonstrate the accuracy and robustness of the proposed method. Finally, we will explore how this level-set DEM can be coupled with the material point method (MPM) to simulate challenging multiscale problems involving discrete-continuum interactions.https://cassyni-user-files-prod.s3.amazonaws.com/QiczxqSMMbbuHjAfdqKL3p https://cassyni.com/slides/outline/Vqk83xVTu44DJXgnNXQ6n1 https://cassyni.com/events/Vqk83xVTu44DJXgnNXQ6n1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TNgsp67UnyvzBHQ75mzWe2 https://cassyni.com/events/Vqk83xVTu44DJXgnNXQ6n1?videoPreview=1 Next-Generation High Energy Density Materialsnohttps://cassyni.com/events/Vqk83xVTu44DJXgnNXQ6n1?videoPreview=12025-10-15T08:00:00+00:003421.68Thieme India ChemTalksNext-generation high energy density materials (HEDMs) are critical for defense, mining, and pyrotechnic applications, yet existing options often present challenges with toxicity, high sensitivity, environmental impact, or insufficient thermal stability. This work focuses on developing safer, more effective HEDMs through strategic molecular design, emphasizing nitrogen-rich heterocyclic systems and accessible synthetic methodologies. Synthetic strategies include skeletal and peripheral editing of backbones, attaching explosophoric groups via facile, cost-effective routes from commercially available starting materials. Materials are characterized using single-crystal X-ray diffraction, thermal analysis (decomposition temperature, Td), and sensitivity measurements (impact, friction). Key findings demonstrate improved secondary explosives, such as oxadiazole-azo and pyrazole systems, with enhanced density, detonation velocity (VOD), and thermal stability (Td ~200 °C). Bridged triazole systems achieved very high thermal stability (>350 °C), approaching or exceeding TATB, suitable for deep-well drilling applications. In hypergolic materials, functional-group editing produced a highly insensitive (IS ≈ 40 J), thermally stable (Td ≈ 160 °C) compound (VOD 8.5 km/s) via a single-step synthesis, significantly enhancing safety. Co-crystallization, as with TNAE and hydrazinium salt, effectively desensitized energetic components and increased thermal stability (Td by 65 °C) through hydrogen bonding. Environmentally friendlier pyrotechnic formulations were developed, where morphological control (micro to submicron particles) enabled tunable impact sensitivity (e.g., 25 J to 2 J). Furthermore, novel lead-free primary explosives, including fluorine-substituted azides and N-methylated nitro-pyrazoles, were synthesized. These exhibit improved safety, ignition capabilities (demonstrated by laser and lead-block tests), and dual functionality, allowing for stable transport with on-demand conversion to sensitive forms. The research delivers versatile HEDMs addressing current limitations in performance and safety.https://cassyni-user-files-prod.s3.amazonaws.com/TNgsp67UnyvzBHQ75mzWe2 https://cassyni.com/events/YJz9HNj66LphfUALvDJjVw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9Zshuopc5zXaCHkFpkwj6N https://cassyni.com/slides/outline/QuG5b82DWUXBuRySN3h73s https://cassyni.com/events/QuG5b82DWUXBuRySN3h73s/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GLKou6aoP8rKBPdJTX6JmU https://cassyni.com/events/QuG5b82DWUXBuRySN3h73s?videoPreview=1 Mind the Gap Workshop Report: AI in Editing and Publishing Workflows: Gaps, Opportunities, and Next Stepsnohttps://cassyni.com/events/QuG5b82DWUXBuRySN3h73s?videoPreview=12026-01-14T13:30:00+00:001580.4Academic Publishing in EuropeWhat happens when publishers, researchers, editors, funders, and open science advocates discuss AI in the same room? The pre-conference workshop “Mind the Gap: AI in Publishing” brought together diverse perspectives to explore what works, what doesn’t, and what needs further attention. This session presents the workshop’s core findings and the co-created “Gap List” – concrete recommendations for responsible AI use in scholarly editing and peer review.https://cassyni-user-files-prod.s3.amazonaws.com/GLKou6aoP8rKBPdJTX6JmU https://cassyni.com/events/7cCqV1gKum6DF4i6ta86pV/seminar/qa https://cassyni.com/slides/outline/7cCqV1gKum6DF4i6ta86pV https://cassyni.com/events/7cCqV1gKum6DF4i6ta86pV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FeEdckzruDsKRkToNg36aJ https://cassyni.com/events/7cCqV1gKum6DF4i6ta86pV?videoPreview=1 Gödel’s Ontological Proof of the Existence of God and its Consistency Consequencesnohttps://cassyni.com/events/7cCqV1gKum6DF4i6ta86pV?videoPreview=12026-02-25T15:00:00+00:004408.24Logica UniversalisGödel’s ontological proof of God’s existence, finalized in 1970, constitutes one of the most ambitious attempts to formalize metaphysical theology using modern logic. Rooted in a tradition stretching from Anselm through Descartes and Leibniz, Gödel’s argument reformulates the classical ontological proof in higher-order modal logic. Yet its significance extends far beyond theology. When stripped of modalities, Gödel’s axioms define an ultrafilter, thereby connecting metaphysical reasoning with foundational set theory and strong axioms of infinity. This talk reconstructs the historical development of ontological arguments, analyzes Gödel’s formal system, examines the phenomenon of modal collapse, and explores the unexpected implications for mathematical foundations, showing that consistency of arithmetic and ZFC is a consequence of the ontological proof. It is argued that Gödel’s proof should be understood not primarily as a theological demonstration but as a profound structural experiment revealing deep connections between logic, metaphysics, and infinity.https://cassyni-user-files-prod.s3.amazonaws.com/FeEdckzruDsKRkToNg36aJ https://cassyni.com/events/F1vuBGPCVdQ3jeEZrSyqEV/seminar/qa https://cassyni.com/slides/outline/F1vuBGPCVdQ3jeEZrSyqEV https://cassyni.com/events/F1vuBGPCVdQ3jeEZrSyqEV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JWu2HTb1tfpuvHdKBjBxqL https://cassyni.com/events/F1vuBGPCVdQ3jeEZrSyqEV?videoPreview=1 Future Leaders of Biophysics 2026nohttps://cassyni.com/events/F1vuBGPCVdQ3jeEZrSyqEV?videoPreview=12026-03-25T14:00:00+00:004981.36Springer Nature Physics CommunityAn International Union for Pure and Applied Biophysics (IUPAB) On-line Event (2 x 15 min talks) for Biophysics Week, 2026. Organised by Springer/Nature, publisher of Biophysical Reviews. Open to all.https://cassyni-user-files-prod.s3.amazonaws.com/JWu2HTb1tfpuvHdKBjBxqL https://cassyni.com/slides/outline/4eLqKYK4gNhQ2qQ431s7Ts https://cassyni.com/events/4eLqKYK4gNhQ2qQ431s7Ts/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9SHLAv71KouyVBdwddKb4S https://cassyni.com/events/4eLqKYK4gNhQ2qQ431s7Ts?videoPreview=1 Opening Remarksnohttps://cassyni.com/events/4eLqKYK4gNhQ2qQ431s7Ts?videoPreview=12026-05-20T07:00:00+00:00421.0Connecting Science, Publishing, and InnovationThe inaugural Nano Summit marks the significant growth and global influence of nanoscience and nanotechnology over the past two decades, a field that has profoundly impacted physics, chemistry, biology, medicine, materials science, and engineering. This expansion is paralleled by the evolution of academic publishing, exemplified by the journal *Small*, which launched in 2005. *Small* recently celebrated its 20th anniversary, having published over 18,000 research articles and 1,800 reviews across 700 issues, with contributions originating from 96 countries. The *Small* journal family has since expanded its scope with the introduction of *Small Methods*, *Small Structures*, and *Small Science*, which is currently celebrating its 5th anniversary. Further milestones observed include the 10th anniversary of *ChemNanoMat* and the recent integration of *Nanophotonics* into the publishing portfolio, alongside recognition for the long-standing contributions of *Crystal Research and Technology*, founded in 1966. To commemorate these developments, a special collection of papers is planned. The summit program highlights the breadth of nanoscience, incorporating emerging topics such as the application of artificial intelligence. The first plenary lecture is delivered by Harald Fuchs, acknowledging his foundational contributions to the field, instrumental role in establishing research centers like CeNTech, and extensive efforts in fostering academic-industrial and international collaborations.https://cassyni-user-files-prod.s3.amazonaws.com/9SHLAv71KouyVBdwddKb4S https://cassyni.com/slides/outline/NRiD6n7qtDZPCPv4JZcBC1 https://cassyni.com/events/NRiD6n7qtDZPCPv4JZcBC1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/iVM26ZprZzZ89mQSUCdpa https://cassyni.com/events/NRiD6n7qtDZPCPv4JZcBC1?videoPreview=1 Episode 3: Conversation with Jeremy Bornigernohttps://cassyni.com/events/NRiD6n7qtDZPCPv4JZcBC1?videoPreview=12025-08-25T08:00:00+00:002315.16Advanced ScienceIn this podcast Dr. Jeremy Borniger (Cold Spring Harbor Laboratory) joins me to discuss cancer and treatment effects on mind-body rhythms. Join us to explore: • Sleep and circadian rhythm influence on immune function • Chemo brain, fatigue and off-target effects • Synchronizing organ rhythms as adjunct therapy https://cassyni-user-files-prod.s3.amazonaws.com/iVM26ZprZzZ89mQSUCdpa https://cassyni.com/events/YJgJ2T4LfNdi3uv5p8NYKw/seminar/qa https://cassyni.com/slides/outline/YJgJ2T4LfNdi3uv5p8NYKw https://cassyni.com/events/YJgJ2T4LfNdi3uv5p8NYKw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BXdBE6gLd68P55dykYuQsY https://cassyni.com/events/YJgJ2T4LfNdi3uv5p8NYKw?videoPreview=1 From systemic barriers to health system solutions: helping families meet their infant feeding intentionsnohttps://cassyni.com/events/YJgJ2T4LfNdi3uv5p8NYKw?videoPreview=12026-07-23T20:00:00+00:003631.08Family MedicineLearning Objectives - Understand how individual factors, social drivers, and systemic issues impact breastfeeding outcomes, particularly for vulnerable and systemically oppressed individuals including Black families and families affected by substance use disorder. - Be aware of how institutionalized and personally mediated racism can impact breastfeeding support - Name at least 3 clinic or unit-level changes that can drive more equitable and high-quality breastfeeding support - Be familiar with the Academy of Breastfeeding Medicine’s clinical guideline on breastfeeding for people with substance use disorder. https://cassyni-user-files-prod.s3.amazonaws.com/BXdBE6gLd68P55dykYuQsY https://cassyni.com/events/3f6sTS3ncBScJu2Fdp6Yaq/seminar/qa https://cassyni.com/slides/outline/3f6sTS3ncBScJu2Fdp6Yaq https://cassyni.com/events/3f6sTS3ncBScJu2Fdp6Yaq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KWJfXSTNZmBAA41XsS1Dot https://cassyni.com/events/3f6sTS3ncBScJu2Fdp6Yaq?videoPreview=1 Thieme Chemistry Best Paper Awardsnohttps://cassyni.com/events/3f6sTS3ncBScJu2Fdp6Yaq?videoPreview=12026-06-24T12:00:00+00:006405.92Thieme GroupJoin us for the Thieme Cheminar “Thieme Chemistry Best Paper Awards” Wednesday, 24 June 2026, 14:00 (CEST) This special online event, brought to you by the journals SYNTHESIS, SYNLETT, and SCNOW, highlights the winners of the 2025 Best Paper Award in each journal. The Thieme Chemistry Best Paper Awards honor the authors of outstanding original research articles selected by the editorial boards for their scientific excellence and impact in synthetic chemistry and related fields. The program will feature award-winning research from leading international scientists: 🔹 Prof. Samer Gnaim (Weizmann Institute of Science, Israel) 🔹 Prof. Go Hira (Kyushu University, Japan) 🔹 Dr. David Palomas (University College London, UK) The session will be chaired by Prof. Tanja Gulder, Associate Editor of SYNLETT Journal. Do not miss this unique opportunity to explore cutting-edge advances across synthetic, sustainable, and interdisciplinary chemistry, and to hear directly from the scientists behind these award-winning discoveries. https://cassyni-user-files-prod.s3.amazonaws.com/KWJfXSTNZmBAA41XsS1Dot https://cassyni.com/slides/outline/BZN3jrLe24bdtFUP17mhnm https://cassyni.com/events/BZN3jrLe24bdtFUP17mhnm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Bu724DL98AHNCjUK9dBWWi https://cassyni.com/events/BZN3jrLe24bdtFUP17mhnm?videoPreview=1 Session 6A: Hydrogen from Bioresources and Wastenohttps://cassyni.com/events/BZN3jrLe24bdtFUP17mhnm?videoPreview=12025-10-22T23:30:00+00:006647.72Centre for Energy TechnologyThis seminar session presented a comprehensive overview of hydrogen production technologies from bioresources and waste, emphasizing biological and thermochemical conversion pathways. The first presentation detailed a novel biocatalyst technology developed by HydGene Renewables, which employs synthetic biology to convert diverse waste biomass-derived crude sugars into carbon-negative, fuel-cell-grade hydrogen on-site via a stable, immobilized microbial catalyst operating at low temperature and pressure without light dependency. This modular system demonstrates scalability and integration potential for industrial decarbonization, notably in ammonia fertilizer production, with hydrogen yields approaching 20–30 kg per ton of biomass and concomitant biogenic CO2 capture. The second presentation focused on biomass gasification and chemical looping hydrogen generation demonstrated in China, achieving 57% energy efficiency and producing high-purity hydrogen and CO2 streams. Innovations in step-wise tar removal combining microwave-assisted cracking and photothermal reforming were introduced to enhance syngas quality and reduce secondary pollution, though scale-up challenges remain. The third presentation assessed Australian biomass and waste resource availability, categorizing feedstocks from agricultural residues to urban waste, highlighting logistical and compositional challenges such as low bulk density and high alkali content that affect thermochemical processing. CSIRO’s research infrastructure supports biomass gasification and syngas utilization for low-carbon fuels. Panel discussions underscored the complementary roles of biological and thermochemical routes, the critical importance of feedstock characterization and supply chain logistics, and the need for integrated, site-specific solutions to advance hydrogen production from bioresources. The session concluded that while biomass availability is substantial but variable, technological innovation and collaborative efforts are essential to realize economically viable, scalable, and sustainable hydrogen production pathways beyond electrolysis.https://cassyni-user-files-prod.s3.amazonaws.com/Bu724DL98AHNCjUK9dBWWi https://cassyni.com/slides/outline/JUU8W3usZqH9XYAMf8H5a5 https://cassyni.com/events/JUU8W3usZqH9XYAMf8H5a5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LVuVGnkQy78PnPWV2cCwgi https://cassyni.com/events/JUU8W3usZqH9XYAMf8H5a5?videoPreview=1 JARS as a Teaching Tool: Helping Students Think and Write Like Scholarsnohttps://cassyni.com/events/JUU8W3usZqH9XYAMf8H5a5?videoPreview=12026-03-26T17:00:00+00:003392.4NoneThe APA Style Journal Article Reporting Standards (JARS) are a useful resource for anyone working with research. Traditionally meant as a guide for manuscript authors and editors, the standards have also proven valuable for instructors and students. Our presenters, Drs. LoriAnn Stretch and Jayna Bonfini, will share **practical strategies for integrating APA Style JARS into assignments, instruction, and feedback**. Join us to learn how JARS can help students: \* clarify the reasoning behind their research \* communicate their work effectively and responsibly \* prepare for research labs and graduate work \* understand the importance of transparency and inclusive reporting **Audience questions and comments are strongly recommended!** Check out our previous webinar to learn about the benefits of using APA Style JARS: [Reporting your research: How to use APA Style Journal Article Reporting Standards](https://cassyni.com/events/Eu6yHeexDbNk5RrT7iZLQD). Image credit: [Kenny Eliason (Unsplash)](https://unsplash.com/photos/a-group-of-people-in-a-room-with-a-projector-screen-1-aA2Fadydc).https://cassyni-user-files-prod.s3.amazonaws.com/LVuVGnkQy78PnPWV2cCwgi https://cassyni.com/events/RtCCCJck9haz27gpd18oz5/seminar/qa https://cassyni.com/slides/outline/RtCCCJck9haz27gpd18oz5 https://cassyni.com/events/RtCCCJck9haz27gpd18oz5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KXhrBVz7sbTYaPAMPMD7G2 https://cassyni.com/events/RtCCCJck9haz27gpd18oz5?videoPreview=1 Crosstalks Episode 2nohttps://cassyni.com/events/RtCCCJck9haz27gpd18oz5?videoPreview=12026-03-12T09:30:00+00:005944.28Advanced Chemical Engineering SeminarsChemical Engineering, Catalysis, and AI — Synergies Shaping the Futurehttps://cassyni-user-files-prod.s3.amazonaws.com/KXhrBVz7sbTYaPAMPMD7G2 https://cassyni.com/events/UMSDRirNLzMUP4APAh3Si1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NUZhJYMT6RqKQn9AezBdTk https://cassyni.com/events/UMSDRirNLzMUP4APAh3Si1?videoPreview=1 American Perspectives on Energy Efficiencynohttps://cassyni.com/events/UMSDRirNLzMUP4APAh3Si1?videoPreview=12019-04-30T06:00:00+00:004434.4 School of Public PolicyOurEnergyPolicy.org and The University of Texas at Austin hosted a conversation about energy efficiency in the National Press Club Ballroom on April 30th. This panel of thought-leaders included Marilyn Brown (Moderator), Judi Greenwald, Lisa Wood and Michael Webber. The panel provided insight into energy efficiency policy issues as they explored the results of two recent surveys that reveal Americans' and energy professionals' perspectives on energy efficiency.https://cassyni-user-files-prod.s3.amazonaws.com/NUZhJYMT6RqKQn9AezBdTk https://cassyni.com/events/F251kQxdWS2gULJRF8HNcm/seminar/qa https://cassyni.com/slides/outline/F251kQxdWS2gULJRF8HNcm https://cassyni.com/events/F251kQxdWS2gULJRF8HNcm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/G6UnM99EPmCKazdXA7ac1C https://cassyni.com/events/F251kQxdWS2gULJRF8HNcm?videoPreview=1 How to get published with the Nature Portfolionohttps://cassyni.com/events/F251kQxdWS2gULJRF8HNcm?videoPreview=12026-08-19T09:00:00+00:003584.04Research Seminars by Springer NatureWe are pleased to invite early career researchers (ECRs) to a webinar exploring the key aspects of scientific publishing, with a particular focus on the standards and best practices of Nature Portfolio journals. The speakers are experienced editors of Nature-branded research and reviews journals. The webinar will provide an overview of the Nature Portfolio journal publishing landscape and will cover editorial process, content types, and peer review. We will also share practical guidance for preparing and submitting scientific manuscripts. The presentation will be followed by a live Q&A session, offering attendees the opportunity to have their questions answered by Nature Portfolio editors. This event is jointly organised by editors from the Nature Portfolio ECR Working Group and the Springer Nature Reviewer Engagement team.https://cassyni-user-files-prod.s3.amazonaws.com/G6UnM99EPmCKazdXA7ac1C https://cassyni.com/slides/outline/KTw5HCJEruwf5TkcSLzPPs https://cassyni.com/events/KTw5HCJEruwf5TkcSLzPPs/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GAxPXuRcu4vKJL6gyvgJMC https://cassyni.com/events/C4D1awbNH3dsG6zNPa2PG9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RJZQxxtTqj9UQY99PLQzEa https://cassyni.com/slides/outline/3B1ihLhzDwR3ZA5Kso5XSV https://cassyni.com/events/3B1ihLhzDwR3ZA5Kso5XSV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XTEgk7K7CeqcJkk2n2cPr6 https://cassyni.com/events/3B1ihLhzDwR3ZA5Kso5XSV?videoPreview=1 Unraveling interactions between extreme-scale wind power systems and stratified, turbulent environmental flowsnohttps://cassyni.com/events/3B1ihLhzDwR3ZA5Kso5XSV?videoPreview=12026-09-24T18:00:00+00:003976.44AI Institute in Dynamic SystemsTo meet net-zero carbon emissions targets by mid-century, up to a -fold increase in wind power capacity is required. To expand energy production, wind turbines are rapidly increasing in size, wind farms are proliferating to new locations and are increasing in size and siting density, and novel wind farm design and control methods are increasingly deployed. But current engineering models driving wind power design and control rely on idealized theory that neglects key aspects of rotor operation within the turbulent, stratified, and sheared atmospheric boundary layer, which are increasingly important for larger turbines and farms. We revisit the first-principles of mass, momentum, and energy conservation to develop a Unified Momentum theory for rotors across operating regimes, accounting for arbitrary misalignments between rotor and inflow and thrust coefficients. The model is validated against large eddy simulations and unique high Reynolds number experiments performed in a pressurized wind tunnel. The Unified Momentum Model generalizes and replaces both classical momentum theory and the Betz limit for rotors operating in uniform and unconfined conditions, and we further generalize the model to account for confinement which is ubiquitous in lab wind tunnel tests or hydrokinetic turbine operation. Moreover, wind turbines always operate in complex atmospheric boundary layer conditions which violate the uniform assumptions in existing rotor aerodynamics theories. We reveal that wind speed and direction shear trigger rotor efficiency losses that can exceed 20%, are not captured in existing engineering models, and increase as wind turbines grow in size. Going from the scale of a turbine to a farm, wake losses can reduce farm energy by 30%, a significant loss that negatively impacts economics and is increasing given wind power expansion. Using large eddy simulations of wind turbines operating in a range of atmospheric conditions, we systematically uncover the significant roles of Coriolis effects and atmospheric stability on wake recovery, trajectory, and morphology. We develop a new fast-running TANDEM (Turbulence ANd DEficit Momentum) wind farm model which accounts for the coupled rotor operational and atmospheric effects on wakes and yields lower error than existing wake models. We perform collective flow control based on the wind farm model, applied in both simulations and utility-scale field experiments. Full-scale field experiments demonstrate that collective flow control increases the energy generation of wind farms through software modifications, without additional turbines or hardware. https://cassyni-user-files-prod.s3.amazonaws.com/XTEgk7K7CeqcJkk2n2cPr6 https://cassyni.com/events/DYdQfhJ1SZ3U5fNTtu2R81/seminar/qa https://cassyni.com/slides/outline/DYdQfhJ1SZ3U5fNTtu2R81 https://cassyni.com/events/DYdQfhJ1SZ3U5fNTtu2R81/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WR16HKCCPNyQPVCD2yUXM8 https://cassyni.com/events/DYdQfhJ1SZ3U5fNTtu2R81?videoPreview=1 Wiley Plant Science Forumnohttps://cassyni.com/events/DYdQfhJ1SZ3U5fNTtu2R81?videoPreview=12026-09-21T07:00:00+00:008033.04Advanced SciencePlant science research stands at a critical juncture, bridging foundational biological mechanisms with agricultural sustainability and global climate resilience. Global publication output in plant biology has expanded substantially, driven largely by open-access growth. Key research frontiers now encompass molecular dynamics such as epigenetics, chromatin regulation, and CRISPR-based genome editing, alongside systems-level integration, multi-omics, plant-microbiome interactions, climate-resilient crop engineering, precision agriculture, and plant-based biomanufacturing. Addressing these frontiers requires resolving major translational bottlenecks, including accelerating the pace of crop innovation to match climate shifts, connecting local studies to global frameworks, and building public trust in advanced agricultural technologies. Publishing strategies and editorial workflows across major plant science and society journals emphasize the importance of conceptual novelty, experimental rigor, and broad community interest. Rigorous evaluation processes typically mandate stable transgenic lines for functional studies alongside comprehensive genetic, molecular, biochemical, and cellular evidence. Journal portfolios, supported by extensive international editorial boards and society memberships, offer author-friendly services such as manuscript transfer pathways, professional copy-editing, and multi-channel global promotion. Furthermore, the integration of artificial intelligence (AI) in research and publishing requires strict adherence to responsible use policies. AI tools are widely accepted for language polishing, translation, and formatting, provided their use is transparently disclosed in methodology sections, whereas human accountability, editorial confidentiality, and the prohibition of AI-generated peer reviews remain strictly enforced to preserve research integrity and scientific quality.https://cassyni-user-files-prod.s3.amazonaws.com/WR16HKCCPNyQPVCD2yUXM8 https://cassyni.com/slides/outline/49fcAE9eqZDaDNQYEuk9Hf https://cassyni.com/events/49fcAE9eqZDaDNQYEuk9Hf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7QJwUiyKJpNBQDj7ExsiTQ https://cassyni.com/events/49fcAE9eqZDaDNQYEuk9Hf?videoPreview=1 Continuous Professional Development in AI: Building a Lifelong Learning Plannohttps://cassyni.com/events/49fcAE9eqZDaDNQYEuk9Hf?videoPreview=12026-02-19T14:00:00+00:003523.24AAMCAI in medical education is evolving—are you keeping up? Assess your own AI knowledge, explore curated resources for continued growth, and create a personalized plan for lifelong learning. Reflect on how you’ve used AI so far and identify new areas to experiment and expand your practice. Stay curious, stay current, and lead the way in responsible AI integration. Objectives: - Assess personal AI knowledge gaps and develop a learning plan. - Explore and share AI-related resources for ongoing professional growth. - Reflect on AI use in medical education and identify areas for further experimentation. This webinar is part of the AI Skill Building for Medical Educators Webinar Series, hosted by the AAMC. For more information, see [the complete series webpage](https://www.aamc.org/learn-network/affinity-groups/group-educational-affairs/webinar-series-ai-skill-building-medical-educators).   CME Information - View the last page of the slide deck for complete instructions on earning CME credit for this recording - CME credit for this learning opportunity is organized by Michigan State University College of Human Medicine Office of Continuing Medical Education - You will be prompted to create an account to obtain credithttps://cassyni-user-files-prod.s3.amazonaws.com/7QJwUiyKJpNBQDj7ExsiTQ https://cassyni.com/slides/outline/Mw2ywTxS3Q5ZNvvYWTVD1o https://cassyni.com/events/Mw2ywTxS3Q5ZNvvYWTVD1o/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7C8yWNa87ozDeLArVQeN6J https://cassyni.com/events/Mw2ywTxS3Q5ZNvvYWTVD1o?videoPreview=1 Simplifying the Submission Process for Authorsnohttps://cassyni.com/events/Mw2ywTxS3Q5ZNvvYWTVD1o?videoPreview=12026-02-25T11:00:00+00:00402.36Researcher to ReaderThe process of publishing scholarly articles can be frustrating for authors, as well as for publishers and reviewers. I propose changes to the process that can ensure fast and accurate publication. The changes include automated data extraction and collaborative authoring, resulting in full transparency and traceability.https://cassyni-user-files-prod.s3.amazonaws.com/7C8yWNa87ozDeLArVQeN6J https://cassyni.com/slides/outline/QQH1AtC4Egr3jsQ749Pqjj https://cassyni.com/events/QQH1AtC4Egr3jsQ749Pqjj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RCGNZDSJ2pBnYDs5RftrZc https://cassyni.com/events/QQH1AtC4Egr3jsQ749Pqjj?videoPreview=1 A2 – Benchmarking Research Performance: Analytics for Strategic Insight and Planningnohttps://cassyni.com/events/QQH1AtC4Egr3jsQ749Pqjj?videoPreview=12026-04-20T09:15:00+00:002709.68Research Analytics SummitEffective research strategy depends on the ability to benchmark performance, understand institutional position, and make informed decisions over time. This session explores how analytics and research performance indicators can be used for institutional benchmarking and strategic analysis across the research enterprise, with Carnegie classifications serving as one illustrative application. Attendees will learn how to interpret research performance methodologies, identify high – impact variables, and monitor trends across research expenditures, doctoral completions, faculty activity, and sponsored funding trajectories. The session demonstrates how dashboards, forecasting models, and early – signal indicators can help leaders assess relative performance, anticipate gaps, and guide strategic investments. Through real – world examples, participants will see how data – informed planning strengthens research intensity, supports sustained performance improvement, and enhances long – term institutional positioning. The approaches presented are broadly applicable to organizations seeking to improve research analytics, benchmarking practices, and strategic decision – making.https://cassyni-user-files-prod.s3.amazonaws.com/RCGNZDSJ2pBnYDs5RftrZc https://cassyni.com/slides/outline/GzYwUdVBepYXyqDCVynDHf https://cassyni.com/events/GzYwUdVBepYXyqDCVynDHf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/U2J35jFD8ehz5QNvEZJ7FL https://cassyni.com/events/GzYwUdVBepYXyqDCVynDHf?videoPreview=1 D5 – From Data to Decisions: Building Responsible Policy Impact Metrics via Policy Citation Datanohttps://cassyni.com/events/GzYwUdVBepYXyqDCVynDHf?videoPreview=12026-04-20T13:30:00+00:002343.24Research Analytics SummitSocietal impact matters – but documenting and measuring policy 'impact' can be confusing. This 45 – minute session using Overton takes participants from foundational concepts to practical implementation, exploring what policy impact data is, why it matters, and how to build measurement systems that drive strategies for institutional improvement. We'll examine different forms of influence within policy documents – from federal agency reports and congressional documents to state guidelines and think tank publications – and discuss meaningful KPIs that align with institutional goals while ensuring data quality and reliability throughout the impact lifecycle. The session emphasizes responsible metrics development: avoiding common pitfalls, maintaining rigorous standards, and creating indicators that enable informed decision – making. Finally, we'll explore semi – automated implementation to ease data collection. Up – to – date policy citations are a strategic and accessible asset, enabling live monitoring of policy engagement patterns. Real – world examples illustrate how institutions use these insights to identify capacity – building opportunities, emerging policy traction, and how to demonstrate tangible improvement over time to stakeholders and funders. Whether you're beginning your policy impact measurement journey or refining existing approaches, this session provides the conceptual framework, quality standards, and practical tools to build metrics that matter.https://cassyni-user-files-prod.s3.amazonaws.com/U2J35jFD8ehz5QNvEZJ7FL https://cassyni.com/slides/outline/KTnxi3ior7K2Lmgm3fgr1b https://cassyni.com/events/KTnxi3ior7K2Lmgm3fgr1b/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BqnFwQDJSMKxNvM61HFzKQ https://cassyni.com/events/KTnxi3ior7K2Lmgm3fgr1b?videoPreview=1 F2 – Who Works on Energy? Can Prompt Engineering Turn General Questions into Actionable Research Intelligence?nohttps://cassyni.com/events/KTnxi3ior7K2Lmgm3fgr1b?videoPreview=12026-04-21T09:15:00+00:002813.12Research Analytics SummitResearch offices increasingly face demands for rapid, comprehensive responses to inquiries about institutional research portfolio, from legislators seeking expertise on policy – relevant topics to campus leaders identifying strategic research strengths. Traditional approaches rely on manual database searches, keyword queries, and time – intensive human analysis. This short presentation describes the design and implementation of an AI – powered research intelligence tool that can assist in communicating institutional research activity. Working with thousands of publication records drawn from our institutional RIMS containing bibliographic metadata, abstracts, and institutional affiliations, we developed a search and synthesis tool using a structure prompt framework within a large language model chatbot. The purpose of the tool is primarily to identify topically and semantically relevant research based on an initial query or queries, generate narrative syntheses aligned with institutional strategic priorities, and produces citation – ready briefs suitable for external stakeholders. This presentation will share lessons learned in prompt engineering for research analytics, discuss the balance between automation and human oversight, and demonstrate practical outputs. Attendees will gain insights into leveraging generative AI for research intelligence while maintaining methodological rigor and ethical evaluation practices.https://cassyni-user-files-prod.s3.amazonaws.com/BqnFwQDJSMKxNvM61HFzKQ https://cassyni.com/events/Xp14s8tvpZ9tESva22Fa9j/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Hc1pvquMBGKbJPj7cT8ZmG https://cassyni.com/slides/outline/2B6p685SV5vuftvVVKxUjw https://cassyni.com/events/2B6p685SV5vuftvVVKxUjw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Fn9nf2LS54Z9mJoNzDPq8z https://cassyni.com/events/2B6p685SV5vuftvVVKxUjw?videoPreview=1 ATEP: A phase space transport model for burning plasmas nohttps://cassyni.com/events/2B6p685SV5vuftvVVKxUjw?videoPreview=12026-03-26T15:00:00+00:003017.72Journal of Plasma PhysicsIn addition to increasingly realistic non-linear global simulations, a hierarchy of theory-based reduced models is needed to complement the predictions concerning the performance of future burning plasmas. Large parameter scans, sensitivity studies and multi-scale physics connecting energetic particle transport with neoclassical transport time scales require tools that go beyond what is presently feasible with first-principles numerical codes. In the view of this challenge we report in his presentation on the implementation and verification of a phase-space resolved energetic particle (EP) transport model. It is based on the Phase Space Zonal Structure transport theory, which extends the conventional transport equations into phase space and consistently evolves a nonlinear equilibrium referred to as the zonal state. Its focus is primarily directed toward understanding the meso-scopic character of EPs and its consequences. Compared to the conventional description of thermal radial transport via a one-dimensional radial diffusion equation, the newly developed model is three dimensional using canonical constants-of-motion variables. The model does not assume diffusive processes to be dominant a priori, instead the EP fluxes can be self-consistently calculated and directly evolved in CoM space. A Fokker-Planck collision operator with orbit-averaged numerical coefficients evaluated on the same CoM coordinate grid allows us to treat EP sources and wave-induced transport consistently on background transport and EP slowing-down time scales. The code named ATEP-3D is fully embedded in ITER IMAS framework and closely connected to the EP-Stability workflow. The workflow contains a hierarchy of analytical, local and global models that as been automated and tested for an extended set of different Alfvénic instabilities in various Tokamak geometries. As a first application, the phase space fluxes are determined either in the limit of constant mode amplitudes, or an energy-conserving quasi-linear model. Comparisons to the global non-linear particle in cell code ORB5 are discussed. First steps of including non-linearly evolving beat-driven zonal fields using an analytical model for radial mode structure and saturation are reported. Various application cases for ASDEX Upgrade, JET, ITER and DEMO are discussed. https://cassyni-user-files-prod.s3.amazonaws.com/Fn9nf2LS54Z9mJoNzDPq8z https://cassyni.com/slides/outline/VqSGo2piU5sDgySXGSTuc1 https://cassyni.com/events/VqSGo2piU5sDgySXGSTuc1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/qekHGUhxw8aYQ6BZrVmTU https://cassyni.com/events/VqSGo2piU5sDgySXGSTuc1?videoPreview=1 Episode 6: A Conversation with Shane Liddelownohttps://cassyni.com/events/VqSGo2piU5sDgySXGSTuc1?videoPreview=12025-11-24T09:00:00+00:002000.04Advanced ScienceAstrocytes, critical non-neuronal cells in the central nervous system, are essential for maintaining normal neuronal function by providing nutrients and clearing metabolic waste. In response to acute infections, trauma, neurodegenerative diseases, and cancer, these cells undergo "reactivity," changing their functions to either support or exacerbate pathological conditions. The study explores the complex heterogeneity and plasticity of astrocytes, noting regional and developmental differences, as well as distinct reactive substates that emerge in specific pathological microenvironments, such as within and surrounding tumors. Functional changes in reactive astrocytes can be both beneficial, as observed in tumor inhibition following methotrexate treatment, and detrimental. While external cues are recognized as primary drivers of astrocyte reactivity, mechanisms governing their deactivation remain less understood. Astrocytes act as key mediators, influencing interactions among neurons, microglia, immune cells, and tumor cells. Advanced tools, including transcriptomic profiling from *in vivo* models and patient samples, are coupled with *in vitro* recapitulation to dissect the functional diversity of these reactive states. Understanding this spatiotemporal and context-dependent astrocyte heterogeneity is crucial for developing highly targeted therapeutic strategies that can selectively modulate astrocyte responses to improve cognitive resilience and brain health in disease contexts like cancer.https://cassyni-user-files-prod.s3.amazonaws.com/qekHGUhxw8aYQ6BZrVmTU https://cassyni.com/slides/outline/QtxELCMU5WLCHsjBFxkuss https://cassyni.com/events/QtxELCMU5WLCHsjBFxkuss/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6tRt6SAZLDbLwKuocFpNvJ https://cassyni.com/events/QtxELCMU5WLCHsjBFxkuss?videoPreview=1 Kidney Talks - Hypertension and Kidneysnohttps://cassyni.com/events/QtxELCMU5WLCHsjBFxkuss?videoPreview=12026-05-21T12:00:00+00:001922.68Education for Primary Care Health Care ProfessionalsHypertension is a significant comorbidity in chronic kidney disease (CKD), with 85% of CKD patients experiencing elevated blood pressure, contributing to high rates of cardiovascular mortality and end-stage kidney disease (ESKD). The pathophysiology of hypertension in CKD involves mechanisms such as salt and water retention, enhanced sympathetic activity, hyperparathyroidism leading to vascular calcification (Monckeberg's arteriosclerosis), and endothelial dysfunction. Diagnosis of hypertension relies on ambulatory (ABPM) or home blood pressure monitoring (HBPM), with targets set below 140/90 mmHg for CKD patients with an albumin-to-creatinine ratio (ACR) less than 70 mg/mmol, and below 130/80 mmHg for those with ACR 70 mg/mmol or greater, or with diabetes. Therapeutic strategies prioritize lifestyle modifications alongside pharmacological intervention. Renin-angiotensin-aldosterone system (RAAS) inhibitors remain a cornerstone, demonstrating efficacy in blood pressure reduction, proteinuria decrease, and preservation of kidney function. Emerging therapies, including SGLT2 inhibitors and finerenone, offer additional prognostic benefits for cardiovascular and renal outcomes, with SGLT2 inhibitors now licensed for CKD independent of diabetes in patients with eGFR less than 45 ml/min/1.73m². Optimising these prognostic agents before deploying other antihypertensives is crucial for comprehensive management, along with routine urine ACR screening for all hypertensive patients to guide risk stratification and treatment.https://cassyni-user-files-prod.s3.amazonaws.com/6tRt6SAZLDbLwKuocFpNvJ https://cassyni.com/slides/outline/TNCFZcb6Go6gepCjoefYbo https://cassyni.com/events/TNCFZcb6Go6gepCjoefYbo/abstract https://cassyni.com/events/TNCFZcb6Go6gepCjoefYbo?videoPreview=1 Online Collaborative Translation in China and Beyond: Community, Practice and Identitynohttps://cassyni.com/events/TNCFZcb6Go6gepCjoefYbo?videoPreview=12023-10-17T08:00:00+00:005622.72Hong Kong Baptist UniversityThis study critically examines online collaborative translation (OCT) practices, particularly within Chinese internet communities, challenging the traditional perception of translation as a solitary undertaking. Employing digital ethnography, with a focus on communities like Yeeyan, the research develops an extended theoretical framework based on Communities of Practice (CoP) theory. This framework integrates concepts of mutual recognition, social narrative theory, situated learning, and knowledge management to comprehensively analyse community, practice, and identity in OCT. Key findings reveal a distinction between machine-centred and human-centred collaborative translation, with OCT primarily characterised by multiple translators producing the same material through a unique cyclical collaborative process. This hybrid linear-cyclical model contrasts with traditional "waterfall" approaches by enabling parallel, continuous revision and dynamic human-to-human interaction. Analysis of diverse cases, including the citizen journalism project Cenci and medical translation initiatives, demonstrates that volunteer translators, often labelled "non-professional," contribute significant expertise, prompting a re-evaluation of professionalism based on knowledge exchange and the pursuit of high-quality translated products. The research underscores the inherently collaborative nature of translation, advocating for OCT's role in expanding translation studies and highlighting its ongoing evolution towards human-machine collaboration, alongside emerging ethical considerations regarding free labour and platformization. https://cassyni.com/slides/outline/2fn3FSErKuQjVMv1HS5Sv9 https://cassyni.com/events/2fn3FSErKuQjVMv1HS5Sv9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/62V9X7xQJroCwSDxwCoVrv https://cassyni.com/events/2fn3FSErKuQjVMv1HS5Sv9?videoPreview=1 Entrepreneurship Through Acquisition - Minority Searcher Preferences & Perceptionsnohttps://cassyni.com/events/2fn3FSErKuQjVMv1HS5Sv9?videoPreview=12025-11-19T20:00:00+00:00998.84Center for Black Entrepreneurship, Spelman CollegeThe increasing racial and gender wealth gap, exacerbated by high failure rates in traditional entrepreneurship (over 50% generally, 60% by year five, and significantly higher for African Americans), necessitates alternative wealth creation strategies. Entrepreneurship Through Acquisition (ETA)—the purchase of existing businesses—mitigates common startup risks related to market validation, customer acquisition, location, and capital access by leveraging established operations. This approach is particularly critical given demographic shifts, including the rising number of women-led households (a majority within ten years, disproportionately impacting Black women) and the US trajectory towards a majority-minority population. This study presents findings from the largest known domestic sample of minority searchers (N=114) engaged in ETA, contrasting with existing research primarily focused on white male searchers. Utilizing open-ended questions, the research investigates their demographic profiles, motivations, preferences, opportunities, and challenges. The sample comprises highly educated professionals in their thirties and forties, with significant prior experience in consulting (21.1%), technology (19.3%), and financial services (11.4%), demonstrating strong transferable skills. Motivations for ETA among this group are often mission-centered, focusing on legacy, community uplift through fair wages, and overcoming professional fatigue, differing from those typically reported in broader ETA research. While acquisition for scaling existing businesses is also pursued, a preference for lower-margin service industries is observed. Significant challenges include racial bias during the acquisition process, especially when acquiring businesses with long-term white ownership and employees, which can introduce "key employee risk" and hinder access to funding. The findings highlight ETA's potential for wealth creation but also underscore the need for targeted education on profitable business types and interventions to address racial barriers in acquisition and financing.https://cassyni-user-files-prod.s3.amazonaws.com/62V9X7xQJroCwSDxwCoVrv https://cassyni.com/slides/outline/A5W6wgwiumiZywSUFJwBL9 https://cassyni.com/events/A5W6wgwiumiZywSUFJwBL9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JMGYRMtxGDrtYb8xQgjh2e https://cassyni.com/events/A5W6wgwiumiZywSUFJwBL9?videoPreview=1 A parallel-kinetic-perpendicular moment model for magnetised plasmasnohttps://cassyni.com/events/A5W6wgwiumiZywSUFJwBL9?videoPreview=12026-05-07T15:00:00+00:002803.6Journal of Plasma PhysicsMany plasma systems, from pulsar magnetospheres to magnetic confinement devices, are highly magnetised. Simultaneously these myriad of plasma environments are often sufficiently tenuous and hot to be best described by kinetic theory and the full six dimensional Boltzmann-Maxwell system of equations, thus making these systems computationally demanding to model. To facilitate new kinetic models of magnetised plasmas, I will discuss a recent innovation which separates the parallel and perpendicular dynamics starting from the kinetic equation while staying agnostic to the inclusion of effects important to consider in diverse environments, such as strong flows in certain fusion reactors, relativistic energies in astrophysical plasmas, or complex boundary conditions and geometry in lab plasma modeling. The key component of the derivation lies in a spectral expansion of only the perpendicular degrees of freedom, analogous to spectral methods which have grown in popularity in recent years for gyrokinetics, while retaining the complete dynamics parallel to the magnetic field. We thus leverage our intuition that a magnetised plasma’s motion is different parallel and perpendicular to the magnetic field, allowing for the treatment of complex phase space dynamics parallel to the magnetic field but at reduced computational cost. The utility of this approach will be demonstrated with a classical benchmark: magnetic reconnection, but in regimes beyond what typical reduced models can capture and culminating in the application of the model to flux rope merging experiments at the Large Plasma Device at UCLA. We will conclude with a look ahead to an additional use-case of this model in the machine learning era: a flexible-fidelity, cost-optimized kinetic model for pre-training and fine-tuning of plasma foundation models that can potentially further accelerate kinetic simulations in this large diversity of magnetised plasma systems. https://cassyni-user-files-prod.s3.amazonaws.com/JMGYRMtxGDrtYb8xQgjh2e https://cassyni.com/slides/outline/Lwo25Mh9yCpmezYk7Fie8m https://cassyni.com/events/Lwo25Mh9yCpmezYk7Fie8m/abstract https://cassyni-user-files-prod.s3.amazonaws.com/YRDQxutABVYy8vQUsFEJHt https://cassyni.com/events/Lwo25Mh9yCpmezYk7Fie8m?videoPreview=1 Causality-Inspired Machine Learning: A Path to more Robust AI Systemsnohttps://cassyni.com/events/Lwo25Mh9yCpmezYk7Fie8m?videoPreview=12026-05-07T12:30:00+00:003126.04MOX Laboratory - Department of MathematicsThe pursuit of reliable and robust machine learning has become a central focus, with statistics and data science playing pivotal roles in its advancement. We explore connections between distributional robustness and causality, providing methodological insights to enhance the reliability of AI systems. We examine the broader implications of these concepts through a case study in digital health and conclude by emphasizing the importance of rigorous real-world validation of machine learning and AI algorithms.https://cassyni-user-files-prod.s3.amazonaws.com/YRDQxutABVYy8vQUsFEJHt https://cassyni.com/events/KxVoyzQ76HiczEik1HFKKs/seminar/qa https://cassyni.com/slides/outline/KxVoyzQ76HiczEik1HFKKs https://cassyni.com/events/KxVoyzQ76HiczEik1HFKKs/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QFVAutuzAzxt9nLY1eE4tE https://cassyni.com/events/KxVoyzQ76HiczEik1HFKKs?videoPreview=1 Through-thickness electrical conductivity of carbon fibre-reinforced polymer composites: successes and failuresnohttps://cassyni.com/events/KxVoyzQ76HiczEik1HFKKs?videoPreview=12026-06-04T13:00:00+00:003740.12Department of AeronauticsCarbon fibre-reinforced polymer (CFRP) composites are widely utilised in primary aircraft structures due to their exceptional strength-to-weight ratios, but modern aviation increasingly demands multifunctionality, such as integrated structural health monitoring. Exterior aero-structures, particularly wings and fuselages, require enhanced through-thickness electrical conductivity to safely dissipate lightning strikes, manage electromagnetic interference (EMI), and prevent resistive heating near fuel zones. This talk reviews and quantitatively evaluates various methodologies to enhance the z-axis conductivity of CFRP, including the integration of conductive nanofillers, polymer nanofibers, and interleaved veils. While certain approaches yield up to a 50-fold increase in electrical conductivity, they often introduce severe manufacturing challenges or degrade interlaminar mechanical properties. Finally, this presentation will discuss strategies to overcome these trade-offs, highlighting future material design pathways and manufacturing scalability required to bridge the gap between lab-scale successes and industrial aerospace implementation.https://cassyni-user-files-prod.s3.amazonaws.com/QFVAutuzAzxt9nLY1eE4tE https://cassyni.com/events/AaBL7178kbCPoi1q1FfUjX/seminar/qa https://cassyni.com/slides/outline/AaBL7178kbCPoi1q1FfUjX https://cassyni.com/events/AaBL7178kbCPoi1q1FfUjX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AXiF9bAaJLfDdpWeyCby9p https://cassyni.com/events/AaBL7178kbCPoi1q1FfUjX?videoPreview=1 Markerless Tracking of the Breastnohttps://cassyni.com/events/AaBL7178kbCPoi1q1FfUjX?videoPreview=12026-06-23T04:00:00+00:003544.28The Auckland Bioengineering InstituteWhen treating breast cancer, the large soft tissue deformations of the breast can complicate accurate localisation of tumours. This effects initial screening, surgery, and follow up care for patients with breast cancer. While soft tissue mechanics can predict internal deformation, lack of information about the shape and position of the patient and their breast can limit their application. While information about the location of the tumour is relevant at many stages of the treatment of breast cancer, it is particularly relevant in breast conserving surgery. Replacing mastectomy, breast conserving surgery aims to remove just the tumour. A successful breast conserving surgery removes a tumour with a small (approx 2~mm) margin, but uncertainty in tumour shape and position can lead to the need for re-excision or mastectomy. This thesis addresses these challenges by developing a model-based approach for precise tracking of breast surface deformation from stereo imaging. This will allow for validating the predictions of physics-based models in positions that account for the changing position of the arm and shoulder. Ultimately, these measurements and models will allow us to convey information for interventions: where a tumour is; how its shape has changed; and how it is embedded within the soft tissue landscape of the breast. This information will help clinicians ensure they accurately find the boundaries of tumours, reducing re-operation rates for breast conserving surgery. The thesis describes three methodological contributions that provide the foundations that will enable up to date markerless tracking of soft tissues and applies these techniques to analyse breast deformation. Firstly, a novel calibration technique for high-precision camera systems suitable for imaging the surface of the breast is described. The proposed methodology works even when the measurements made by the camera system are more precise than the fabrication methods of the calibration targets. Secondly, to increase the robustness of the breast surface tracking, it describes how sparse features observed in multiple cameras are incorporated within a parameterised mesh surface. This allows for the creation of parameterised time-varying meshes that represent a deforming surface. Finally, a mesh-based refinement scheme is introduced for taking sparse features and densely tracking the surface of the breast. A time varying mesh serves as an estimates of motion, which is then refined to densely track the breast surface. Validation was performed by comparing the proposed markerless approach with a marker based approach. The breast surface was imaged with a multi-camera system designed to track the surface of the breast. During arm movements that caused up to 35 mm displacement of the breast skin surface, the approach recovered breast surface displacements to within 0.5 mm of the marker-based approach. Together, these contributions provide the foundation for the creation of stereo camera systems capable of tracking the deformation of the breast, with the goal of supporting clinicians as they improve outcomes for patients with breast cancer. https://cassyni-user-files-prod.s3.amazonaws.com/AXiF9bAaJLfDdpWeyCby9p https://cassyni.com/events/MSUFEfrZp2JbUTYFuMqcJy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8XKuyLPiJgCPGenVJ16xzJ https://cassyni.com/events/MSUFEfrZp2JbUTYFuMqcJy?videoPreview=1 How to Perform a Peer Reviewnohttps://cassyni.com/events/MSUFEfrZp2JbUTYFuMqcJy?videoPreview=12026-06-10T08:00:00+00:001130.4MultiPsych JournalLearn how to perform a peer review in this video by MultiPsych Editorial Board Member Dr Khutaija Noor, Global Ambassador for the Foundation of Clinical Research at Harvard University. https://cassyni-user-files-prod.s3.amazonaws.com/8XKuyLPiJgCPGenVJ16xzJ https://cassyni.com/slides/outline/UrCJvvZSPtcRy34isEhLiy https://cassyni.com/events/UrCJvvZSPtcRy34isEhLiy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7mo9GEhxdunFexhSd7m7N6 https://cassyni.com/events/UrCJvvZSPtcRy34isEhLiy?videoPreview=1 Bringing Data Culture into the Futurenohttps://cassyni.com/events/UrCJvvZSPtcRy34isEhLiy?videoPreview=12026-06-12T13:00:00+00:003760.16AAMCSpeakers explore the core domains of data culture and examine the questions, struggles, and compromises that new technologies inevitably introduce into how organizations use and govern data. They highlight where strong data culture can help teams be proactive rather than reactive and map out the critical conversations institutions need to have now—and again in six months and one year—to stay ahead of rapid shifts in analytics, AI, and digital transformation. This webinar is part of the Artificial Intelligence in Academic Medicine Webinar Series, hosted by the AAMC. It explores critical concepts, the current landscape, and practical strategies drawn from various perspectives and institutions to support you in navigating the evolving world of AI in academic medicine. For more information, see [the complete series webpage](https://www.aamc.org/about-us/mission-areas/medical-education/artificial-intelligence-ai-academic-medicine-webinar-series). https://cassyni-user-files-prod.s3.amazonaws.com/7mo9GEhxdunFexhSd7m7N6 https://cassyni.com/slides/outline/XKSLALo4bBNvKyYHQvbySu https://cassyni.com/events/XKSLALo4bBNvKyYHQvbySu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3rhzjLjd3MqTRuGRzKrDmG https://cassyni.com/events/XKSLALo4bBNvKyYHQvbySu?videoPreview=1 Exploring and mitigating the effects of extreme heat on blueberry pollination and pollinatorsnohttps://cassyni.com/events/XKSLALo4bBNvKyYHQvbySu?videoPreview=12026-06-04T07:40:00+00:00648.8Spring weather in the Great Lakes region of the United States has included short periods of very high temperatures in recent years. Some of these extreme heat events occurred during flowering of blueberry (Vaccinium corymbosum), followed by poor yields in the regions' blueberry farms. We investigated the response of blueberry flowers to field-relevant periods of high heat, and the subsequent effects on blue orchard bees (Osmia lignaria) provided pollen from heat stressed plants. Blueberry pollen germination and tube growth were inhibited by conditions exceeding 32ºC, and a brief exposure of 4 hours caused irreversible damage to the pollen. Varying the timing of heat stress relative to flower development revealed that bud swell was a particularly sensitive period of development. A no-choice cage study showed that mason bees (Osmia lignaria) foraging on plants previously exposed to brief extreme heat had lower fecundity, disrupted development, and lower survival to adulthood when larvae consumed pollen from these plants compared to those without extreme heat exposure. The implications of these results for managing crops through extreme heat conditions will be discussed, along with our current research to develop mitigation strategies to protect crop yields through increasingly variable weather conditions.https://cassyni-user-files-prod.s3.amazonaws.com/3rhzjLjd3MqTRuGRzKrDmG https://cassyni.com/slides/outline/6d27rASpeHgyAXFYti1smF https://cassyni.com/events/6d27rASpeHgyAXFYti1smF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4MdqHeFp9u9d9LER8MkuVY https://cassyni.com/events/6d27rASpeHgyAXFYti1smF?videoPreview=1 Probing plasma equillibration processes with (new) astrophysical shocksnohttps://cassyni.com/events/6d27rASpeHgyAXFYti1smF?videoPreview=12026-07-16T15:00:00+00:002871.68Journal of Plasma PhysicsCollisionless shocks are common in astrophysical environments ranging from vicinities of compact stellar objects to outskirts of massive nodes in the cosmic large scale structure (groups and clusters of galaxies). Dramatic improvement in the observational capabilities of X-ray observatories over the last decade allowed us to study such shocks in very low density environments, where action of plasma equillibration processes takes long enough time that regions affected by non-equillibrium conditions can be directly resolved. I'll discuss a few very recent examples of this kind associated with unusual remnants of supernova explosions, galaxy-scale outflows and merger shocks in galaxy clusters. https://cassyni-user-files-prod.s3.amazonaws.com/4MdqHeFp9u9d9LER8MkuVY https://cassyni.com/events/Gzh43n4cfdBAiXH3tf5kfw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9SxXcwJSqRygdd4m3UcGRk https://cassyni.com/events/FWkEuj83MFWWHoHw3EQLny/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5GCkkhyr9aFA5VvhEePv8v https://cassyni.com/events/NvwtYgaynFZhGC5NtvcFiM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9DeC9qo2HV1rC9DdsWJSBY https://cassyni.com/events/LxP6UaWmRnH2iibL9LpbAd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8ozzzbLWRHoCjhdymkLDyQ https://cassyni.com/events/YLMetDyWq2DJsHxmckB3Fj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CpwYrdGrLAB2HkL7eBozS2 https://cassyni.com/events/4eUwtgtVhBL2mXTuRhAer9/seminar/qa https://cassyni.com/slides/outline/4eUwtgtVhBL2mXTuRhAer9 https://cassyni.com/events/4eUwtgtVhBL2mXTuRhAer9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WEvzSaBPCkxcnBR96BTcJA https://cassyni.com/events/4eUwtgtVhBL2mXTuRhAer9?videoPreview=1 Protein folding in the cell: The power of basic research to provide fundamental insights into human diseasenohttps://cassyni.com/events/4eUwtgtVhBL2mXTuRhAer9?videoPreview=12026-08-12T08:30:00+00:004185.12Advanced ScienceProf. F.-Ulrich Hartl is a distinguished German biochemist renowned for his groundbreaking discovery of chaperone-mediated protein folding. His work revolutionized cell biology by overturning the long-held assumption that proteins fold spontaneously into their active shapes.His foundational breakthrough occurred in the late 1980s alongside collaborator Arthur Horwich. Together, they identified molecular chaperones as mandatory biological machines that assist newly synthesized proteins. Hartl detailed how chaperones like GroEL/GroES act as physical protective cages, encapsulating individual protein molecules to prevent toxic aggregation.In recent years, Prof. Hartl's research focuses heavily on the direct link between chaperone dysfunction, cellular aging, and neurodegenerative disorders. His laboratory at the Max Planck Institute studies how manipulating these protein-folding networks could halt toxic plaque accumulation in diseases like Alzheimer's, Parkinson's, and Huntington's.A highly cited scientist, Prof. Hartl has received numerous prestigious awards for his medical contributions. He was previously honored with the Albert Lasker Award, the Shaw Prize, and the Breakthrough Prize in Life Sciences. His recent accolades include the 2022 HFSP Nakasone Award, the 2023 Schleiden Medal, and the 2024 BBVA Foundation Frontiers of Knowledge Award.Today, Prof. Hartl continues to actively guide therapeutic research aimed at harnessing chaperone mechanisms to combat age-related neurodegeneration. This is a public lecture originally presented at the 32nd Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB) Conference on August 12, 2026. The lecture was live-streamed by Wiley Advanced and subsequently authorized by Prof. Ulrich Hartl for replay on Wiley’s affiliated platforms.https://cassyni-user-files-prod.s3.amazonaws.com/WEvzSaBPCkxcnBR96BTcJA https://cassyni.com/events/4B37m5Q5aEcBRCCxwScT3T/seminar/qa https://cassyni.com/slides/outline/4B37m5Q5aEcBRCCxwScT3T https://cassyni.com/events/4B37m5Q5aEcBRCCxwScT3T/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Tjz1i3Pv2Mfq56a59CxF4r https://cassyni.com/events/4B37m5Q5aEcBRCCxwScT3T?videoPreview=1 In Centre Haemodialysis: Problem-based learning 1130-1300nohttps://cassyni.com/events/4B37m5Q5aEcBRCCxwScT3T?videoPreview=12025-09-18T10:30:00+00:006555.76Imperial College Renal and Transplant Centre1130 Optimising people for Transplantation from Dialysis 1215 People with Mental Illness treated with Dialysis Image credit: [Frankie Cordoba (Unsplash)](https://unsplash.com/photos/a-neon-sign-that-says-it-always-seems-impossible-until-its-done-8W5Uw571B_c).https://cassyni-user-files-prod.s3.amazonaws.com/Tjz1i3Pv2Mfq56a59CxF4r https://cassyni.com/events/KU6oxyPZH5W1xKw29kd3Bb/seminar/qa https://cassyni.com/slides/outline/KU6oxyPZH5W1xKw29kd3Bb https://cassyni.com/events/KU6oxyPZH5W1xKw29kd3Bb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BevaScCB7iyRBgRC9AhwoC https://cassyni.com/events/KU6oxyPZH5W1xKw29kd3Bb?videoPreview=1 AI-driven small molecules drug discoverynohttps://cassyni.com/events/KU6oxyPZH5W1xKw29kd3Bb?videoPreview=12026-02-19T11:00:00+00:004426.64The Pharmacological Research family of journalsArtificial intelligence (AI) helps solve problems in various fields, including drug discovery, through its capability to process and analyze large amounts of data in a short period of time. AI-aided drug screening is less time-consuming and less expensive compared to experimental trial-and-error-based screening. Using an AI-based framework that learns the relationship between the structures of small molecules and their biological properties offers new perspectives on molecular design. This presentation introduces the use of multiple machine learning models to predict biological activities based on molecular representations, such as molecular fingerprints and line notations of molecular structures. This method is highly effective for molecular design across many targets. The accuracy of the models was assessed using error metrics and R-squared values relative to experimental IC50 values. The models were then applied to virtual screening to identify top candidates, and their binding affinities to viral protein targets were validated using molecular modeling techniques.https://cassyni-user-files-prod.s3.amazonaws.com/BevaScCB7iyRBgRC9AhwoC https://cassyni.com/events/2C3yyXbaBMRcgrrjsBMVFb/seminar/qa https://cassyni.com/slides/outline/2C3yyXbaBMRcgrrjsBMVFb https://cassyni.com/events/2C3yyXbaBMRcgrrjsBMVFb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9bTe5HmMBqhQ8hMYta17mY https://cassyni.com/events/2C3yyXbaBMRcgrrjsBMVFb?videoPreview=1 Paving the way to wastewater purification via constructed wetlandnohttps://cassyni.com/events/2C3yyXbaBMRcgrrjsBMVFb?videoPreview=12024-01-30T11:00:00+00:004702.08ElsevierConstructed wetlands (CWs) are a most important nature-based technology for wide range of wastewater treatment and have been employed worldwide for decades. The treatment efficiency of CWs depends on their configuration and is a function of various parameters including wastewater type, substrate, and operation conditions etc. Optimizing configuration, developing novel operational strategy, and wiser use of treatment process coupled with other system in CW for a better treatment efficiency are always the research topic in R&D of CWs. This talk summarizes the series studies with the most recent update of CW development. It is expected that the talk can provide useful information and roadmap of CWs R&D and thus help overseeing CWs technology and promoting CW’s further development and application. https://cassyni-user-files-prod.s3.amazonaws.com/9bTe5HmMBqhQ8hMYta17mY https://cassyni.com/slides/outline/Us9UpL5a6A78yhR8HFV21T https://cassyni.com/events/Us9UpL5a6A78yhR8HFV21T/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JzdQJpzJzQ6aYQsokAiEwx https://cassyni.com/events/Us9UpL5a6A78yhR8HFV21T?videoPreview=1 Understanding complex materials using advanced electron microscopynohttps://cassyni.com/events/Us9UpL5a6A78yhR8HFV21T?videoPreview=12024-02-13T12:00:00+00:004475.4Department of AeronauticsElectron microscopy has seen tremendous developments over the last couple years providing unprecedented possibilities in materials characterization at the nanometer and atomic scale. With the high spatial resolution and high beam currents available in aberration corrected (S)TEM, highly sensitive detectors for imaging and spectroscopy and fast readout speeds, new microscopy methods have been established, which enable advanced insights into materials, their 2D/3D structure and chemistry as well as some of their functional properties. With this presentation, I want to provide an overview of the techniques and illustrate the information that can be obtained by transmission electron microscopy. Examples will include atomic resolution imaging and spectroscopy and different 4D-STEM approaches to understand structure and properties (electric, magnetic or mechanical) of oxide-based quantum materials, advanced aluminium alloys and metallic glasses.https://cassyni-user-files-prod.s3.amazonaws.com/JzdQJpzJzQ6aYQsokAiEwx https://cassyni.com/slides/outline/G1cpsStf1bUTopvUkQz8fo https://cassyni.com/events/G1cpsStf1bUTopvUkQz8fo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2iB3qyr8kwiV1xTBWjNwGS https://cassyni.com/events/G1cpsStf1bUTopvUkQz8fo?videoPreview=1 Preparing the Future: Ethics of Peace and Warnohttps://cassyni.com/events/G1cpsStf1bUTopvUkQz8fo?videoPreview=12023-10-25T12:00:00+00:004426.28Hong Kong Baptist UniversityHow are ethical traditions of peace and war changing, moving beyond limitations on war, toward building environmentally and socially sustainable peace?https://cassyni-user-files-prod.s3.amazonaws.com/2iB3qyr8kwiV1xTBWjNwGS https://cassyni.com/slides/outline/B58nQcRQd1wSQjD8jwH8wf https://cassyni.com/events/B58nQcRQd1wSQjD8jwH8wf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6xEb7M8JhBZ9iQyyGYW93t https://cassyni.com/events/B58nQcRQd1wSQjD8jwH8wf?videoPreview=1 Yoonie Han performs Saint-Saëns Piano Concerto No. 2 with Brunensis Virtuosi Orchestranohttps://cassyni.com/events/B58nQcRQd1wSQjD8jwH8wf?videoPreview=12021-11-28T12:00:00+00:00775.0Hong Kong Baptist UniversityKorean-American award winning & Billboard chart top player, pianist Yoonie Han plays Saint-Saens second piano concerto I. Andante Sostenuto in Italy.https://cassyni-user-files-prod.s3.amazonaws.com/6xEb7M8JhBZ9iQyyGYW93t https://cassyni.com/events/TrkzGQgxWAseZbAsNavUXo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/U8WZNLnxGZA7X1Qp3pc3Bk https://cassyni.com/events/TrkzGQgxWAseZbAsNavUXo?videoPreview=1 Does the Christian View of Hell Make Any Sense?nohttps://cassyni.com/events/TrkzGQgxWAseZbAsNavUXo?videoPreview=12023-01-25T12:00:00+00:005916.92Hong Kong Baptist UniversityIn this episode, I'm joined by Fr. James Rooney to discuss whether or not the traditional view of Hell held by most Christians (aka "Eternal Conscious Torment") is an intellectually viable position to hold.https://cassyni-user-files-prod.s3.amazonaws.com/U8WZNLnxGZA7X1Qp3pc3Bk https://cassyni.com/slides/outline/CAhUwUuqrs7ZDD7ENWmoj https://cassyni.com/events/CAhUwUuqrs7ZDD7ENWmoj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Brw6e2f3cNbq3zZy5yKAoY https://cassyni.com/events/CAhUwUuqrs7ZDD7ENWmoj?videoPreview=1 Visitor experience and the translation of identity: The case of visitors to museums of the Chinese diasporanohttps://cassyni.com/events/CAhUwUuqrs7ZDD7ENWmoj?videoPreview=12022-05-10T12:00:00+00:005174.72Hong Kong Baptist UniversityIn the expanding literature on museum translation, the visitor experience remains an under-researched area. While an increasing body of work by Translation Studies scholars has explored such issues as multimodal interactions in the exhibition space, curatorial perspectives on translation quality, or the effect of shifts in the target text, there has to date been relatively little empirical evidence of the role of translation in the visitor experience – whether translation is understood in the sense of interlingual transfer or of broader cultural representation. Equally, in the Museum Studies context, while much has been done to explore the visitor experience, such work frequently comes from monolingual or monocultural perspectives. Museums of diaspora form a particularly interesting focus for such enquiry since they raise a number of questions relating to the translation of identity in the exhibition space, and how visitors both from different linguacultural backgrounds and from different sectors of the home culture variously respond to the experiences of the diaspora in question. The present study focuses on museums of the Chinese diaspora in the US. Employing a mixed methods approach that includes detailed visit diaries and follow-up interviews, as well as online reviews, the study examines how the collective lived experience of the diaspora as “translated” in the museum exhibition is in turn translated in terms of the visitor’s personal experience through a series of intertexts that are “cognitively-realized” (Neather 2012). The study further considers how interlingual translation plays a part in shaping these visitor interactions.https://cassyni-user-files-prod.s3.amazonaws.com/Brw6e2f3cNbq3zZy5yKAoY https://cassyni.com/slides/outline/3fQiiMiY39dbv9gfn4RQXf https://cassyni.com/events/3fQiiMiY39dbv9gfn4RQXf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/76EypDpBYbn4BeYdiWfPxr https://cassyni.com/events/3fQiiMiY39dbv9gfn4RQXf?videoPreview=1 Christian Perspective on Ethicsnohttps://cassyni.com/events/3fQiiMiY39dbv9gfn4RQXf?videoPreview=12021-08-26T12:00:00+00:00466.24Hong Kong Baptist UniversityDoes ethics make sense? Isn't it all subjective? How do we learn about ethics?https://cassyni-user-files-prod.s3.amazonaws.com/76EypDpBYbn4BeYdiWfPxr https://cassyni.com/slides/outline/AaVBMvmtBZPPQxgF9VzLgM https://cassyni.com/events/AaVBMvmtBZPPQxgF9VzLgM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7hCzgNbbMNPJDtve2rGvsG https://cassyni.com/events/AaVBMvmtBZPPQxgF9VzLgM?videoPreview=1 Improvise! 2021 Symposium Closing Concertnohttps://cassyni.com/events/AaVBMvmtBZPPQxgF9VzLgM?videoPreview=12021-03-29T12:00:00+00:00632.04Hong Kong Baptist UniversityThe closing concert of the Improvise! 2021 Symposium presented an experimental performance integrating violin, electronics, and electrified acoustics to explore the boundaries of live musical improvisation. The event emphasized real-time interaction between traditional string instrumentation and electronic sound modification, highlighting the dynamic interplay between acoustic and digital sound sources. The performance incorporated elements of life modification through electronic processing, creating a hybrid sonic environment that challenged conventional notions of musical structure and direction. The improvisational approach foregrounded spontaneous creation and responsiveness, with the musicians navigating uncertain sonic trajectories and engaging in exploratory sound gestures. This synthesis of acoustic and electronic media demonstrated the potential for expanded expressive capabilities in contemporary improvisational practice. The concert underscored the significance of technology as both a tool and collaborator in live performance, suggesting future directions for research and artistic development in electroacoustic improvisation and hybrid musical forms.https://cassyni-user-files-prod.s3.amazonaws.com/7hCzgNbbMNPJDtve2rGvsG https://cassyni.com/slides/outline/MSL8fXH8oDfxjmUQWgY4vh https://cassyni.com/events/MSL8fXH8oDfxjmUQWgY4vh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6xG3fauHJDbCh2zoeYPBjt https://cassyni.com/events/MSL8fXH8oDfxjmUQWgY4vh?videoPreview=1 Spatial History & Virtual Mapping of the Battle of Hong Kong 1941nohttps://cassyni.com/events/MSL8fXH8oDfxjmUQWgY4vh?videoPreview=12023-01-17T12:00:00+00:003536.76Hong Kong Baptist UniversityThis event showcases two very exciting and complementary uses of virtual mapping in telling the story of the Battle of Hong Kong.https://cassyni-user-files-prod.s3.amazonaws.com/6xG3fauHJDbCh2zoeYPBjt https://cassyni.com/slides/outline/HynuLjkTj1oKi5Aqs2A7Ps https://cassyni.com/events/HynuLjkTj1oKi5Aqs2A7Ps/abstract https://cassyni-user-files-prod.s3.amazonaws.com/bizqr4ydP6p1DmaBiaeF8 https://cassyni.com/events/HynuLjkTj1oKi5Aqs2A7Ps?videoPreview=1 Introduction - Ep.01nohttps://cassyni.com/events/HynuLjkTj1oKi5Aqs2A7Ps?videoPreview=12021-04-27T12:00:00+00:00197.52Hong Kong Baptist UniversityThe HKBU Phonology Laboratory, established in 2012, supports both teaching and research in experimental linguistics by providing specialized equipment, software, and workspace. The laboratory facilitates studies in speech production, speech perception, and language processing through a range of tools including sound mixers, portable recorders, head-worn microphones, and remote-controlled devices for natural speech recording. Non-invasive technologies such as ultrasound and electromagnetic articulography (EMA) enable detailed analysis of articulatory gestures and movements. For language processing research, the lab employs an EyeLink Portable DUO eye-tracking system to monitor eye movements during reading, listening, and cognitive tasks, with portability allowing field studies. Experiment programming and data analysis are supported by software such as Paradigm and E-Prime, widely used by students and researchers. Additionally, the lab has developed a free mobile application designed to assist learners in phonetics, focusing on the International Phonetic Alphabet and articulatory features of consonants and vowels. This comprehensive infrastructure aims to provide foundational resources and practical guidance for beginners in experimental linguistics, enhancing both educational and research capabilities within the field.https://cassyni-user-files-prod.s3.amazonaws.com/bizqr4ydP6p1DmaBiaeF8 https://cassyni.com/slides/outline/LT2va9z5vJZp51eQQi4k7o https://cassyni.com/events/LT2va9z5vJZp51eQQi4k7o/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WcogxbuHZJzNuXiocRGXHG https://cassyni.com/events/LT2va9z5vJZp51eQQi4k7o?videoPreview=1 Prof. Kwai-cheung Lo's opening speechnohttps://cassyni.com/events/LT2va9z5vJZp51eQQi4k7o?videoPreview=12022-09-08T12:00:00+00:00417.0Hong Kong Baptist UniversityThis symposium addresses the concept of ecological civilization, a universal concern, with particular attention to China's unique constitutional commitment to this objective. The discussion focuses on China-related environmental issues, building on prior work exploring China-related spaces for the Anthropocene cultural imaginary. The analysis centres on elemental phenomena—cloud, heat, sea, and wind—understood as both fundamental components of the world and as dynamic, fluid bodies characterized by flows, turbulence, contingency, and deviation. These elements are conceptualized not merely as static entities, but as media that transmit meanings and enable action, reflecting humanity's intimate relationship with the environment and the damages inflicted upon it. This approach posits that these unstable elemental modes can offer new insights into existence within systems no longer in constant equilibrium. The symposium critically engages with China's ecological civilization campaigns, which endeavor to impose an imaginary of balance and harmony between economic growth and ecological protection. By examining cloud, heat, sea, and wind, the symposium seeks to uncover alternative imaginations and amplify diverse perspectives on global ecological conditions, providing a counterpoint to established narratives.https://cassyni-user-files-prod.s3.amazonaws.com/WcogxbuHZJzNuXiocRGXHG https://cassyni.com/slides/outline/Ur4CMmz1P5yoELzsUZPoLh https://cassyni.com/events/Ur4CMmz1P5yoELzsUZPoLh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FRRMPFU66PgQDFTyhWKj5p https://cassyni.com/events/Ur4CMmz1P5yoELzsUZPoLh?videoPreview=1 Redefining Art Presentation in the Digital Eranohttps://cassyni.com/events/Ur4CMmz1P5yoELzsUZPoLh?videoPreview=12021-09-09T12:00:00+00:009295.64Hong Kong Baptist UniversityThis seminar explored how digital advancements are redefining art presentation, focusing on the concept of "Art in the Cloud" as a new paradigm for creative expression and audience engagement, particularly accelerated by global shifts towards virtual connection. Multiple artistic approaches were presented, spanning hybrid online-to-offline models and critical examinations of digital platforms. One approach involved leveraging emerging technologies, such as NFT certification for digital sculptures created using 3D point cloud GANs, while critically assessing the environmental impact of proof-of-work blockchains and the market's potential for democratization. Other artists explored immersive experiences through VR and AR applications, drawing inspiration from natural systems like the rhizosphere to model interconnected, non-hierarchical networks for art, science, and society. The interplay between physical and digital was also examined through digital craft, presenting kinetic sculptures that translate ephemeral digital processes into tangible material forms. Several artists investigated the implications of digital interfaces for identity and presence. Works explored the construction of synthetic digital identities using face recognition algorithms and social media data, or critiqued the erosion of physical presence through telematic performances that highlight the limitations and "failures" inherent in online streaming. Interactive installations were developed to enable remote physical walkthroughs of miniature galleries via robotic cameras, inviting contemplation on the ontology of digital images, audience attention, and cultural identity. Collectively, these presentations emphasize art's role in questioning the boundaries between the real and virtual, fostering new forms of collaboration and communication, and critically engaging with technology as both a tool for innovation and a subject for profound societal reflection.https://cassyni-user-files-prod.s3.amazonaws.com/FRRMPFU66PgQDFTyhWKj5p https://cassyni.com/slides/outline/XKJDbCDdaNkHbHUS2FJS4d https://cassyni.com/events/XKJDbCDdaNkHbHUS2FJS4d/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QanYLkBix3JVbfx1JP2BM8 https://cassyni.com/events/XKJDbCDdaNkHbHUS2FJS4d?videoPreview=1 A Book of Treesnohttps://cassyni.com/events/XKJDbCDdaNkHbHUS2FJS4d?videoPreview=12021-09-17T12:00:00+00:002692.72Hong Kong Baptist UniversityThis abstract explores the intersection of landscape theory, computer games, and artistic practice, examining how technological shifts mediate our relationship with the physical environment. A novel machine learning system was developed to generate three-dimensional tree forms. This system was trained on a dataset created from 70 hand-generated 3D tree models, inspired by art-historical paintings and the Lindenmayer system, which were then randomized and expanded to approximately 26,000 models before being processed into voxel space. The machine learning approach, designed to learn shapes rather than explicit tree attributes, encountered significant challenges in generating cohesive organic forms. Unlike simpler objects, the system struggled with trees, often producing disconnected "floating objects" due to its lack of inherent knowledge about branch connectivity. The artistic process involved creating ink paintings that were subsequently paired with the machine-generated outputs, aiming to achieve a "modern representation of a tree" through this hybrid method of painting and computational averaging. The project also incorporates a virtual reality film featuring poems that narrate the historical and personal stories of trees in Hong Kong, from pre-colonial feng shui practices to British reforestation efforts using imported species, and contemporary administrative forestry. This multidisciplinary study investigates how emerging technologies reshape visual perception and artistic expression, while critically reflecting on human interpretations of nature and the socio-historical transformation of landscapes.https://cassyni-user-files-prod.s3.amazonaws.com/QanYLkBix3JVbfx1JP2BM8 https://cassyni.com/slides/outline/6ct1H1sPdV4LRqBhW2iLNy https://cassyni.com/events/6ct1H1sPdV4LRqBhW2iLNy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/K62YAQ7XrBuHQWn7PKfJsQ https://cassyni.com/events/6ct1H1sPdV4LRqBhW2iLNy?videoPreview=1 67: James Shea, author of Last Day of My Facenohttps://cassyni.com/events/6ct1H1sPdV4LRqBhW2iLNy?videoPreview=12025-08-28T12:00:00+00:003935.48Hong Kong Baptist UniversityThis month on the Deerfield Public Library Podcast, we are very excited to share our conversation with poet, writer, and translator James Shea, whose extraordinary new collection of poems, Last Day of My Face (University of Iowa Press, 2025), was recently published as a winner of the prestigious Iowa Poetry Prize. James Shea’s work delights in word play and unexpected images with a voice set at and considering the edges of meaning. As you’ll hear in our conversation, Shea draws from the traditions of haiku and The New York School, giving us humorous and elegiac meditations on our shared predicament as minds trying to make sense of emergency. Or, as Shea puts it at the start of the long poem, “Failed Self-Portrait,” which ends his new collection—and our conversation—“I’ve made a sort of makeshift / sense of ourselves…” What makes this conversation especially meaningful is that our recording was also a reunion; my colleague, Adult Services Librarian Stevie Noguchi, and I each had James Shea as a poetry professor when he taught in Chicago over a decade ago. Stevie joins me as co-host for this special episode. You’ll also hear Shea’s reflections on the art of translation, poetic lineage, and readings from the treasure trove of recent publications Shea has put out, as translator and editor, including: Applause for a Cloud (Black Ocean, 2025), Shea’s translations of haiku by Japanese poet Sayumi Kamakura, The Routledge Global Haiku Reader (Routledge, 2023), an introduction to current issues within haiku studies, which Shea co-edited with Grant Caldwell, and, Moving a Stone: Selected Poems of Yam Gong (Zephyr Press, 2022), co-translated with novelist Dorothy Tse and introducing Hong Kong poet Yam Gong to English-language readershttps://cassyni-user-files-prod.s3.amazonaws.com/K62YAQ7XrBuHQWn7PKfJsQ https://cassyni.com/slides/outline/77XcKhWv4wcPRbib6U18eH https://cassyni.com/events/77XcKhWv4wcPRbib6U18eH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5zjXymQac7XqBLrQhZsyxz https://cassyni.com/events/77XcKhWv4wcPRbib6U18eH?videoPreview=1 Music as Life Companion for Well-Being Throughout the Lifespannohttps://cassyni.com/events/77XcKhWv4wcPRbib6U18eH?videoPreview=12022-11-21T12:00:00+00:002643.24Hong Kong Baptist UniversityResearch into music psychology has highlighted the marked effects that listening to music has on sense of well-being, quality of life and emotions. This lesson offers an overview of the importance of listening to music and its role in health and well-being throughout life. A wide range of evidence suggests that singing lullabies during pregnancy can strengthen the bond between mother and child. In adolescents, music can help build personal and social identity, promoting self-control, self-expression and participation in the community. Adults often listen to music in everyday life to regulate emotions and psycho-physiological functions. In difficult situations, like the Covid-19 pandemic, many people found music a resource for coping with and managing isolation. Music also continues to offer valuable support for better health in old age.https://cassyni-user-files-prod.s3.amazonaws.com/5zjXymQac7XqBLrQhZsyxz https://cassyni.com/slides/outline/gPxpBQ9EuXK2jUMVZ1Leq https://cassyni.com/events/gPxpBQ9EuXK2jUMVZ1Leq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TcJ5Z5ZzdREX6yVfaEx3pi https://cassyni.com/events/gPxpBQ9EuXK2jUMVZ1Leq?videoPreview=1 Interview with Adam Wong on ‘The Way We Talk’nohttps://cassyni.com/events/gPxpBQ9EuXK2jUMVZ1Leq?videoPreview=12025-08-02T12:00:00+00:001601.56Hong Kong Baptist UniversityThe Way We Talk is the latest film from acclaimed director Adam Wong 黃修平 (The Way We Dance and She Remembers, He Forgets), known for his genre-defying storytelling. With a sensitive and objective lens, Wong leads audiences into the world of the Deaf community, offering a narrative that is both inclusive and deeply human. Blending powerful performances with an emotionally layered script, The Way We Talk follows the intersecting journeys of three young people navigating life between the worlds of sound and silence. At its heart, the film explores Deaf culture, identity, and the many forms of communication that connect and sometimes divide us.https://cassyni-user-files-prod.s3.amazonaws.com/TcJ5Z5ZzdREX6yVfaEx3pi https://cassyni.com/slides/outline/5A5ipn49puNnmemMUJdoAm https://cassyni.com/events/5A5ipn49puNnmemMUJdoAm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UnLgpNcAYAMKTiWJDSn61L https://cassyni.com/events/5A5ipn49puNnmemMUJdoAm?videoPreview=1 Development and Validation of Overset Methods in PyFRnohttps://cassyni.com/events/5A5ipn49puNnmemMUJdoAm?videoPreview=12021-07-29T14:00:00+00:002062.28PyFROverset methods enable us to effectively simulate problems with moving geometries, such as turbines and flapping wings. With rapid advances in high performance architectures, such as graphics processing units (GPU), a new type of parallel direct cut method was recently developed by Crabill et al., which foresees the applications of flux reconstruction methods with the overset capability to implicit large eddy simulation (ILES) of turbines, rotorcrafts, etc., which operate at moderate Reynolds number. We will talk about the integration of the parallel direct cut method into PyFR, especially for the GPU backend, coupled with the arbitrary Lagrangian-Eulerian method for moving objects. Both inviscid and viscous benchmark cases will be used to validate the developed methods.https://cassyni-user-files-prod.s3.amazonaws.com/UnLgpNcAYAMKTiWJDSn61L https://cassyni.com/slides/outline/SPzKvoPc6x7sj7D9YXg7EV https://cassyni.com/events/SPzKvoPc6x7sj7D9YXg7EV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3bGsTWcQ9p7xmaMnvDPPzE https://cassyni.com/events/KUusHELFxYN6EJDaB67B5o/seminar/qa https://cassyni.com/slides/outline/KUusHELFxYN6EJDaB67B5o https://cassyni.com/events/KUusHELFxYN6EJDaB67B5o/abstract https://cassyni-user-files-prod.s3.amazonaws.com/J2Q4KiLg6N4FxJoktEV2tW https://cassyni.com/events/KUusHELFxYN6EJDaB67B5o?videoPreview=1 Questaal: A package of electronic structure methods based on the linear muffin-tin orbital techniquenohttps://cassyni.com/events/KUusHELFxYN6EJDaB67B5o?videoPreview=12021-07-27T15:00:00+00:002780.08Computer Physics CommunicationsQuestaal is a set of codes developed for calculating the electronic structure of materials from first principles. Developed by Mark van Schilfgaarde and his collaborators, Questaal descends from the work of Ole K. Andersen and his group in Stuttgart during the 80's on the linear muffin-tin orbital (LMTO) method. This is an atom-centred basis set that is by construction particularly efficient for solving the band structure problem. As Questaal has evolved, a variety of codes and techniques aimed at addressing both different material problems and implementing different levels of theory have been developed. These include methods based on the atomic sphere approximation, where a simplified description of the crystal potential can be exploited to facilitate calculations that are scarcely possible otherwise: recent calculations of the supercurrent in Josephson junction devices formulated in terms of non-equilibrium Green's functions calculated ab initio (using density functional theory) demonstrate that this method continues to be extremely useful. At the other end of the spectrum, highly accurate calculations for more basic material studies can be conducted using Questaal's implementation of quasiparticle self-consistent GW (QSGW). QSGW is a way to achieve a measure of self-consistency in Hedin's perturbative GW method, thereby solving problems associated with the starting point dependence of GW and increasing its reliability significantly. QSGW provides a fully ab initio description of a broad range of materials that is generally much better than density functional theory or its common extensions (eg LDA+U). Questaal also includes the ability to extend QSGW to problems with stronger correlation by adding ladder diagrams (via the Bethe-Salpeter equation), or by coupling QSGW with DMFT, these representing the current state-of-the-art. This talk will describe the background, capabilities, some methodological aspects, and future directions of the Questaal project.https://cassyni-user-files-prod.s3.amazonaws.com/J2Q4KiLg6N4FxJoktEV2tW https://cassyni.com/slides/outline/LUHwiVAy3YFWhEF4voncaH https://cassyni.com/events/LUHwiVAy3YFWhEF4voncaH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JVebL9RvrXFbCxDgzAR4Lv https://cassyni.com/events/LUHwiVAy3YFWhEF4voncaH?videoPreview=1 Parity-Time (PT) symmetry in chiral electromagnetic metamaterialsnohttps://cassyni.com/events/LUHwiVAy3YFWhEF4voncaH?videoPreview=12021-04-27T14:00:00+00:003544.2MetaMATCombining chirality and Parity-Time-symmetry in a single metamaterial structure one can achieve a variety of novel propagation and scattering characteristics. These characteristics include mixed PT-related phases, multiple exceptional points, asymmetric reflection, asymmetric optical activity, and others. In the talk, besides discussing the possibility and conditions for the simultaneous coexistence of PT-symmetry and chirality, I will discuss all the above characteristics along with the potential to control them and exploit in a variety of applications related with electromagnetic wave polarization control.https://cassyni-user-files-prod.s3.amazonaws.com/JVebL9RvrXFbCxDgzAR4Lv https://cassyni.com/slides/outline/UsKDW7AtWKfVrZbXzf7foB https://cassyni.com/events/UsKDW7AtWKfVrZbXzf7foB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CwGgDZrci3Fdgii9azbQsG https://cassyni.com/events/UsKDW7AtWKfVrZbXzf7foB?videoPreview=1 Reflectionless Modes: an alternative spectrum for wave scatteringnohttps://cassyni.com/events/UsKDW7AtWKfVrZbXzf7foB?videoPreview=12020-11-24T14:00:00+00:005622.52MetaMATTo characterize scattering resonances, a useful tool is the complex resonance spectrum corresponding to eigenmodes (QNM) able to leak energy. However, for reflection/transmission problems (e.g. waveguides, gratings or screens), the complex resonance spectrum does not directly quantify transmission efficiency, and the question of good or perfect transmission is of tremendous importance in many topics of intense study in wave physics: extraordinary optical transmission, topological states immune to backscattering, perfect transmission resonances, transmission eigenchannels through disordered media, reflectionless metamaterials or metasurfaces. We present here an alternative spectrum allowing one to identify situations where perfect transmissions occur [1]. The operator yielding the spectrum of reflectionless modes is non-selfadjoint, and it is PT-symmetric for systems with spatial mirror symmetry. Eigenmodes (reflectionless modes) and eigenvalues (reflectionless complex frequencies) will be presented in various scattering situation, from the simplest 1D setup to several 2D waveguide geometries.https://cassyni-user-files-prod.s3.amazonaws.com/CwGgDZrci3Fdgii9azbQsG https://cassyni.com/slides/outline/69ToG2truuGDEanrE2KEfF https://cassyni.com/events/69ToG2truuGDEanrE2KEfF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6Pxe8UxyGrgXNw9xF4gQ3g https://cassyni.com/events/69ToG2truuGDEanrE2KEfF?videoPreview=1 Nonlocal minimal surfaces are generically stickynohttps://cassyni.com/events/69ToG2truuGDEanrE2KEfF?videoPreview=12021-09-23T13:00:00+00:002852.48Partial Differential Equations and ApplicationsSurfaces which minimize a nonlocal perimeter functional exhibit quite different behaviors than the ones minimizing the classical perimeter. Among these peculiar features, an interesting property, which is also in contrast with the pattern produced by the solutions of linear equations, is given by the capacity, and the strong tendency, of adhering at the boundary. We will discuss this phenomenon and present some recent results. https://cassyni-user-files-prod.s3.amazonaws.com/6Pxe8UxyGrgXNw9xF4gQ3g https://cassyni.com/slides/outline/XLZEjXQWhcRzDW56YM2JX7 https://cassyni.com/events/XLZEjXQWhcRzDW56YM2JX7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QfkeQh1zLkAp7JQbMPBe9k https://cassyni.com/events/XLZEjXQWhcRzDW56YM2JX7?videoPreview=1 Valley-Hall topological acousticsnohttps://cassyni.com/events/XLZEjXQWhcRzDW56YM2JX7?videoPreview=12021-10-12T14:00:00+00:003409.92MetaMATThe discrete valley degree of freedom, i.e., quantum states of energy extrema in momentum space, is attracting growing attention because of its potential as a new type of information carrier like spins in spintronics. Transferring the valley concept to classical wave systems through valley-like frequency dispersions, has been made possible using engineered artificial lattices such as photonic and sonic crystals. In this webinar, we will start with a brief introduction on valley-projected topological acoustics and then discuss our recent works in this topic, which include the experimental realizations of the topological acoustic delay line[1], the directional acoustic antenna[2] and the valley-projected edge states based on the subwavelength soda cans[3]. Lastly, in this context, we also consider non-Hermiticity combining sonic crystals with gain[4]. Here, we take advantage of electro-thermoacoustic coupling from biased carbon nanotube films used as lattice coatings. We construct a topological whispering gallery made out of such coated lattice and show how the mode chirality can be broken and a topological “saser”, the analogous topological “laser” in acoustics, can be realized.https://cassyni-user-files-prod.s3.amazonaws.com/QfkeQh1zLkAp7JQbMPBe9k https://cassyni.com/slides/outline/3gDn2cfEicVgCRZ4mEWsf3 https://cassyni.com/events/3gDn2cfEicVgCRZ4mEWsf3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5eZ11W8zUR3jKgzg6ZezLe https://cassyni.com/events/3gDn2cfEicVgCRZ4mEWsf3?videoPreview=1 Grammar rules OK?nohttps://cassyni.com/events/3gDn2cfEicVgCRZ4mEWsf3?videoPreview=12020-05-15T16:00:00+00:003866.44Linguistics and Applied Language StudiesThis is not a research seminar; it is more a series of reflections on the (recent) history of linguistic thought and the problems of deciding what a grammar is, how a rule works, and whether we have alternative ways of interpreting grammatical information that may be of more practical use.https://cassyni-user-files-prod.s3.amazonaws.com/5eZ11W8zUR3jKgzg6ZezLe https://cassyni.com/slides/outline/Pvro9uDXX73vYd1Fn8zk21 https://cassyni.com/events/Pvro9uDXX73vYd1Fn8zk21/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6DQumn9TinT64pKNAcXxKG https://cassyni.com/events/Pvro9uDXX73vYd1Fn8zk21?videoPreview=1 Revisiting topological materials: crystal optics and the Chern numbernohttps://cassyni.com/events/Pvro9uDXX73vYd1Fn8zk21?videoPreview=12022-03-01T14:00:00+00:003907.64MetaMATIt is now well established that the number and direction of interface waves trapped between different materials can be calculated using topology. Typically we use the wave-vector k as coordinates on a closed surface (a torus for example), and then compute the first Chern number from the waveform at each value of k. If this number differs between two materials, it indicates the presence of trapped states at their interface. Useful and fascinating as this is, there is also a great deal of mystery here: what exactly is the Chern number recording? and could we have found these modes in a simpler way? This talk attempts to answer these questions. I will begin by briefly reviewing the mathematics underlying these topological calculations, showing that the Chern number is recording special points in the dispersion relation where an effective refractive index vanishes. Examining these points of vanishing index using good old fashioned crystal optics, we find that the refractive index is zero in a complex direction. The complexity of the direction indicates a direction of allowed circulation (analogous to circular polarization), as required for a one-way interface state. Using examples from near field optics, elasticity, and coupled resonator theory, it is then shown that this zero index condition provides a shortcut to the results from equivalent topological calculations.https://cassyni-user-files-prod.s3.amazonaws.com/6DQumn9TinT64pKNAcXxKG https://cassyni.com/slides/outline/7dTrdLsD2zmusHJmQfqyGy https://cassyni.com/events/7dTrdLsD2zmusHJmQfqyGy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7NPa9dAmFV4B5iia2sQagE https://cassyni.com/events/7dTrdLsD2zmusHJmQfqyGy?videoPreview=1 Spatial and Temporal Wave Variability at the Basque Coast: From wave energy at regional scales to runup of individual wavesnohttps://cassyni.com/events/7dTrdLsD2zmusHJmQfqyGy?videoPreview=12022-04-12T10:40:00+00:002443.04Water WavesThe Basque Coast, located in the southeastern corner of the Bay of Biscay, is subject to a highly variable wave regime - both spatially and temporally. Accurate computations of the nearshore wave processes are often necessary to improve coastal risk management and to assess the local potential for wave energy exploitation. Here, we pay attention to the variability of the local wave regime computed from offshore to nearshore and up to the beach level. The third generation spectral wave model SWAN builds a 44-year wave hindcast over the South Aquitaine coastal area and consequently describes the spatio-temporal variability of the wave climate. Especially near steep bathymetric features, such as the Capbreton submarine canyon, pronounced longshore gradients become evident. Regarding the temporal variability, some seasonal variability is observed but no significant long-term trend of an inter-annual variability can be identified. Wave breaking can induce critical loads on offshore structures. This work also focuses on wave-load estimations based on bulk parameters from a simplified wave breaking probability to characterize the survivability of wave energy converts. This facilitates operational planning and identification of potential sites for the installation of devices. The use of phase-resolving models is becoming increasingly popular when focusing on small spatial scales and complex environments such as embayed beaches, where features such as rocky islands or engineered shorelines influence the wave regime. Here, the BOSZ model is utilized to compute wave-by-wave transformations and swash zone processes in the complex environment of Grande Plage of Biarritz. Comparisons with field data show that the model is able to reproduce the overall cross-shore wave transformations as well as swash processes with low errors under a wide range of conditions (tide levels and wave conditions). Both the temporal and spatial variability of the swash are well captured by the model. Spectral analyses highlight that the significant swash height computed for high frequencies (f ≥ 0.05 Hz) contains the highest variability and also shows strong sensitivity to the wave conditions. Based on numerical data, it appears that the nearshore morphology plays a key role in the distribution of wave energy at a local scale and strongly influences the alongshore distribution of the runuphttps://cassyni-user-files-prod.s3.amazonaws.com/7NPa9dAmFV4B5iia2sQagE https://cassyni.com/slides/outline/AbJEgBias2FThEYe8g5ooj https://cassyni.com/events/AbJEgBias2FThEYe8g5ooj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7YJ1M92789xvcJ6f4mA1xa https://cassyni.com/events/AbJEgBias2FThEYe8g5ooj?videoPreview=1 Nonlinear Schrödinger systems with large interaction forces between different componentsnohttps://cassyni.com/events/AbJEgBias2FThEYe8g5ooj?videoPreview=12020-11-09T15:00:00+00:003441.32Partial Differential Equations and ApplicationsThere have been many studies on the asymptotic behavior of low energy solutions for a single elliptic equation as an involved parameter approaches to a threshold. In this case, the asymptotic behavior depends on a balance between the differential operator and nonlinearity, and their interaction with a geometry of a underlying domain. On the other hand, even though the elliptic systems coming from nonlinear Schrödinger systems have a simple looking interaction terms, even the construction of nontrivial low energy solutions is not easy in general since the Morse indices of the nontrivial solutions could be high depending types of interaction terms. When the interaction forces between different components are very large, we believe that a relatively simpler structure we can see.Nevertheless, a wide variety of their asymptotic behavior we could imagine as various kinds of combination for the interaction between components might produce various effects on the asymptotic behavior.The general study for elliptic systems with large interaction forces is quite challenging. In this talk, I would like to introduce my recent studies with collaborators on three components systems as basic steps to get general understanding for elliptic systems with large interaction forces.https://cassyni-user-files-prod.s3.amazonaws.com/7YJ1M92789xvcJ6f4mA1xa https://cassyni.com/slides/outline/heyxWb2N9D1ex521ejD7K https://cassyni.com/events/heyxWb2N9D1ex521ejD7K/abstract https://cassyni-user-files-prod.s3.amazonaws.com/MkGZxjT4M2WidgaqTQJA7g https://cassyni.com/events/heyxWb2N9D1ex521ejD7K?videoPreview=1 Towards scalable Photonic Neural Networks with (3+1)D integrated opticsnohttps://cassyni.com/events/heyxWb2N9D1ex521ejD7K?videoPreview=12021-11-02T14:00:00+00:004726.96MetaMATIntegrated photonic architectures have the potential to revolutionize neural network computing. However, conventional 2D lithography strongly limits the size of integrated photonic neural networks due to fundamental scaling laws. We want to overcome this problem by integrating neural networks using 3D printed photonic waveguides. For that we demonstrate complex 3D multimode waveguide networks based on polymer waveguides surrounded by air. Furthermore, we recently developed a (3+1)D direct laser writing technique where we dynamically and locally control the writing power in order to realize single mode step or graded index waveguides.https://cassyni-user-files-prod.s3.amazonaws.com/MkGZxjT4M2WidgaqTQJA7g https://cassyni.com/slides/outline/Tt21QjsqdQZMBomXtgeLzH https://cassyni.com/events/Tt21QjsqdQZMBomXtgeLzH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AkaKsmGpghzcm9jii8VGHt https://cassyni.com/events/Tt21QjsqdQZMBomXtgeLzH?videoPreview=1 Transition and equilibria in stratified shear flownohttps://cassyni.com/events/Tt21QjsqdQZMBomXtgeLzH?videoPreview=12020-10-14T14:00:00+00:002813.64Department of AeronauticsStratified shear flows control the degree of mixing of salt and heat occurring in the world’s oceans. An understanding of the nonlinear flow structures which lead to, and mediate turbulent mixing in these flows is therefore vital in order to accurately model their effect on the Earth’s energy balance. This talk will outline a constrained variational procedure which identifies nonlinear flow structures which are most likely to cause turbulence in stratified shear flows. We find that the inclusion of even small buoyancy effects in the flow significantly affects the sequence of events which trigger a turbulent mixing event. An important structure which mediates this transition sequence are edge states – exact, steady-state, unstable equilibria of the Navier-Stokes equations. We will examine these structures in closer detail, and investigate their dynamics over a large range of flow parameters, focussing in particular on the effect of the Prandtl number.https://cassyni-user-files-prod.s3.amazonaws.com/AkaKsmGpghzcm9jii8VGHt https://cassyni.com/events/QRY2KDNwMvXkN5zmaF7iCD/seminar/qa https://cassyni.com/events/QRY2KDNwMvXkN5zmaF7iCD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6UTsoCV3pzq18WmVbuuz5L https://cassyni.com/events/MTb9orU1vTMfMz552nFwPB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/G4Ya87UiQNwfjmfBBfBveS https://cassyni.com/slides/outline/H1oxcxg4n4EEc3os25W5k9 https://cassyni.com/events/H1oxcxg4n4EEc3os25W5k9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9yoR8Cayhbp2752EeFxq3L https://cassyni.com/events/H1oxcxg4n4EEc3os25W5k9?videoPreview=1 Burning Man's Mathematical Underbellynohttps://cassyni.com/events/H1oxcxg4n4EEc3os25W5k9?videoPreview=12021-02-27T15:30:00+00:001236.08Mathematical IntelligencerNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/9yoR8Cayhbp2752EeFxq3L https://cassyni.com/slides/outline/JzNkh4kH8XWu9XHumfHkHs https://cassyni.com/events/JzNkh4kH8XWu9XHumfHkHs/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7d9RCEj6EFG81eB88iP6Wz https://cassyni.com/events/JzNkh4kH8XWu9XHumfHkHs?videoPreview=1 Communicating health knowledges across clinic and community: The case of sex characteristics in plurilingual Hong Kongnohttps://cassyni.com/events/JzNkh4kH8XWu9XHumfHkHs?videoPreview=12022-04-08T04:00:00+00:003386.44Linguistics and Applied Language StudiesThe human body displays an array of variations of sex characteristics, ranging from expected, normalized variations (i.e. endosex) to minority ones that do not meet medical and/or social norms of binary male and female (i.e. intersex). Naming and classification systems have material consequences for general access to health care but also mental wellbeing. To date, the small amount of language-focused scholarship on sex characteristics and variation has been epistemologically oriented to the metropole. That is, theories developed in ‘global centres’ have been applied to data in ‘peripheral locales’ rather than being reframed or broadened by the ideas there encountered. This study uses metapragmatic discourse analysis (i.e. analysis of talk about language) to mitigate cultural appropriation and commodification, treating interviewees as collaborators who analyze language in a process of joint discovery with the researcher. The data is drawn from interviews with two Hong Kong Chinese health professionals, one an intersex-bodied Chinese Medicine specialist and the other an endosex-bodied Endocrinology specialist. Discourse analysis of the audio-recorded interviews, following the principles of interactional sociolinguistics, serves to reveal affordances and constraints of the globally circulating yet locally interpreted terminology that is available in English, Cantonese and Mandarin. They both relate the painstaking and cautious process of trying to appropriate or coin terms to refer to ‘intersex’ and 'disorders of sex development' in Cantonese spoken discourse (the latter in the medical domain and the former in other domains). In so doing, the interviewees position English and Mandarin terms, circulating into and around multilingual Hong Kong, as requiring a great deal of pondering. Stances are taken on the need for localized terms that are not socially stigmatizing regardless of domain. Another stance taken is that a term’s written and spoken forms must take equal precedence, and the distinct features of Cantonese homophones, tonalities and semantic prosodies must be considered. Terms circulating in from the English-speaking ‘world’ and from mainland China must be scrutinized by Cantonese-speaking insiders so as to anticipate and avoid social pitfalls. Links are drawn to findings in other geopolitical regions, not to create a tally of ‘cases’ that prompt further universalizing discourses, but in hope of contributing to a co-mediation of knowledges. It is a focus that more respectfully brings Asian and multilingual perspectives into the conversation.https://cassyni-user-files-prod.s3.amazonaws.com/7d9RCEj6EFG81eB88iP6Wz https://cassyni.com/slides/outline/97P3emHtx1Wr9XbUyXawXK https://cassyni.com/events/97P3emHtx1Wr9XbUyXawXK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6GN1KMhQ2Eju69Nneb2NoQ https://cassyni.com/events/97P3emHtx1Wr9XbUyXawXK?videoPreview=1 Transliterating in Time and Spacenohttps://cassyni.com/events/97P3emHtx1Wr9XbUyXawXK?videoPreview=12022-05-06T04:00:00+00:003663.44Linguistics and Applied Language StudiesTrans-languaging emerges in multilingual educational settings when students communicate across their native and codified languages effortlessly. The pandemic has revealed how that although the mother tongue can complement the codified language context in a classroom, indigenous minority languages remain marginalised in the online world. Trans-languaging is now rendered into text online and speech automatically via deep learning. Google translate allows users to quickly translate an unlimited number of characters into another language if those languages have a large online database. However, not all languages enjoy this status.‘Transliterating’ captures the practices that emerge in digital space as solutions for reading and writing in multilingual and multi-script societies. Transliterating has no limit apart from digital resources (data). Indeed, these practices are codified in formal teaching of literacy in Japanese classrooms and observed in educational contexts in India. In Africa, transliterating is a less formal but effective grassroots approach to teaching literacy in multilingual settings without access to any digital resources. The result is transliterating nurtures local language expertise by valorizing local practices and local knowledge. It therefore maximizes bilingual ability. For instance, a teacher can develop a lesson plan using an alphabet and translate the text instantly into another language used as the medium of instruction and delivered in any geographic location in the world. This allows students to use each their native language for assessment and thus adds fairness to the online learning environment. Transliterating also enables students excluded by non-native language-literacy such as adopted and fostered children, in-married women, refugees, and economic migrants and also generates cultural and linguistic ‘meta-linguistic awareness’ based on innovative teaching.https://cassyni-user-files-prod.s3.amazonaws.com/6GN1KMhQ2Eju69Nneb2NoQ https://cassyni.com/slides/outline/RuTDLdodGwGgeLHV96rgSZ https://cassyni.com/events/RuTDLdodGwGgeLHV96rgSZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5resVLveHB8qN4PP3tYbca https://cassyni.com/events/RuTDLdodGwGgeLHV96rgSZ?videoPreview=1 Mapping the structural connectome in the living human brain, where are we?nohttps://cassyni.com/events/RuTDLdodGwGgeLHV96rgSZ?videoPreview=12022-04-26T04:00:00+00:004147.64The Auckland Bioengineering InstituteDiffusion MRI Tractography is today the only imaging technique able to map the structural connectivity of the human brain in vivo non-invasively. Thanks to these unique capabilities, tractography has become one of the pillars of modern neuroimaging and it is now adopted in several neuroscience and clinical research applications worldwide. In this lecture, Dr. Dell'Acqua will review how tractography has evolved from early DTI-based methods to the more advanced tractography techniques to study healthy and pathological white matter and its complex connectivity. The talk will present what are the opportunities offered by the new methods but also the existing challenges that still need to be taken into consideration when using tractography. The last part of the talk will cover some recent methods developed by Dr. Dell'Acqua's group and how they can be applied to improve the analysis of large scale tractography datasets. Dr Dell'Acqua is a senior lecturer at Institue of Psychiatry, Psychology and Neuroscience, King's College London and the current chair of the Diffusion Study Group at the International Society for Magnetic Resonance in Medicine (ISMRM). His work focuses on the development and application of new advanced Diffusion Magnetic Resonance Imaging and Tractography methods in both clinical settings and research.https://cassyni-user-files-prod.s3.amazonaws.com/5resVLveHB8qN4PP3tYbca https://cassyni.com/events/5ADqPvdaqi1RWLqCrywLZ3/seminar/qa https://cassyni.com/events/5ADqPvdaqi1RWLqCrywLZ3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AH7xs3ErHwdCVB7uw2qK8r https://cassyni.com/slides/outline/4AvdJZLXxnuGqb1Cm1U1k9 https://cassyni.com/events/4AvdJZLXxnuGqb1Cm1U1k9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9yQmCcacXHoQxDsLYKjW8e https://cassyni.com/events/4AvdJZLXxnuGqb1Cm1U1k9?videoPreview=1 Paraconsistent Orbits of Logicsnohttps://cassyni.com/events/4AvdJZLXxnuGqb1Cm1U1k9?videoPreview=12022-02-16T11:40:00+00:004633.04Logica UniversalisSome strategies to turn any logic into a paraconsistent system are examined. In the environment of universal logic, we show how to paraconsistentize logics at the abstract level using a transformation in the class of all abstract logics called paraconsistentization by consistent sets . Moreover, by means of the notions of paradeduction and paraconsequence we go on applying the process of changing a logic converting it into a paraconsistent system. We also examine how this transformation can be performed using multideductive abstract logics. To conclude, the conceptual notion paraconsistent orbit of a logic is proposed.https://cassyni-user-files-prod.s3.amazonaws.com/9yQmCcacXHoQxDsLYKjW8e https://cassyni.com/slides/outline/F3BvKba5cs5kMrqENYhhgy https://cassyni.com/events/F3BvKba5cs5kMrqENYhhgy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JckqWaQJCoUkokS28RGtRC https://cassyni.com/events/F3BvKba5cs5kMrqENYhhgy?videoPreview=1 From Necessary Truths to Feelingsnohttps://cassyni.com/events/F3BvKba5cs5kMrqENYhhgy?videoPreview=12021-07-14T10:40:00+00:005471.88Logica UniversalisI take into account Schopenhauer’s study of Leibniz’s work, as it emerges not only from his explicit critique in his dissertation On the Fourfold Root of the Principle of Sufficient Reason (1813) and in The World as Will and Idea (3rd edition 1859), but also from his annotations of Leibniz’s writings. Schopenhauer owned many books of Leibniz in his private library and they are full of intriguing annotations. Many of these annotations concern the discussion on logic and mathematical truths and so they are particularly relevant for the study of Schopenhauer’s philosophy of mathematics. After a comparison between Leibniz and Schopenhauer’s definition of necessary and innate truths, I put alongside what the two authors stated about system and fundamental axioms. Two questions arise from Leibniz’s interpretation of Euclid’s axioms: the role of ‘images’ in knowledge and the notion of ‘confused’ knowledge. These two questions are worth of attention, as they allow to focus on Schopenhauer’s theory of ‘feeling’ mathematical knowledge, as I show in the last section of this paper. To Schopenhauer, knowledge works with intuitive representations, intuition, perception, and, for this reason, feeling is the basis of all conceptions. Schopenhauer’s provided a new point of view regarding feeling and intuitive knowledge that involves a special meaning for his philosophy of mathematics.https://cassyni-user-files-prod.s3.amazonaws.com/JckqWaQJCoUkokS28RGtRC https://cassyni.com/slides/outline/B5wqisN7JUoWh15Xj7Nc53 https://cassyni.com/events/B5wqisN7JUoWh15Xj7Nc53/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QadjL6Kps68cq3StXPDe6A https://cassyni.com/events/B5wqisN7JUoWh15Xj7Nc53?videoPreview=1 Rare earth nitrides - Ferromagnetic semiconductors, and what else??nohttps://cassyni.com/events/B5wqisN7JUoWh15Xj7Nc53?videoPreview=12022-09-08T00:15:00+00:003956.52The MacDiarmid Institute for Advanced Materials and NanotechnologyMost of the 14 rare-earth nitrides are intrinsic ferromagnetic semiconductors. Their magnetism in the 4f shell has a strong spin-orbit interaction, a contrast to the quenched orbital magnetic moments in transition-metals. The contribution of both spin and orbital moments delivers vastly contrasting magnetic properties across the series; coercive fields and magnetisations span orders of magnitude. Alloy compositional tuning allows variation of the magnetic properties i.e. S, L, J, M, which can in principle be independently selected. All promise enhanced efficacy in devices, and doping control of conduction further broadens their technical potential. Along with a brief description of the thin-film growth at the core of our programme, I will describe highlights from our 15 years exploring these materials [1]: their huge range of magnetic states [2,3], their coupled electronic-magnetic responses [4,5], progress in devices and a surprising incidence of heavy-fermion superconductivity [6,7]. These studies are supported by DFT computations, a variety of laboratory-based measurements and synchrotron X-ray spectroscopies.https://cassyni-user-files-prod.s3.amazonaws.com/QadjL6Kps68cq3StXPDe6A https://cassyni.com/slides/outline/KV3yrNugyLzixzHRZmQiU5 https://cassyni.com/events/KV3yrNugyLzixzHRZmQiU5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6ingKYJp3j73y1R3rgWFM8 https://cassyni.com/events/KV3yrNugyLzixzHRZmQiU5?videoPreview=1 Augmenting Human Memory through Cognition-Aware AI-based Technologiesnohttps://cassyni.com/events/KV3yrNugyLzixzHRZmQiU5?videoPreview=12022-07-26T04:00:00+00:003048.04The Auckland Bioengineering InstituteMemory is a cognitive ability used in our everyday lives. However, our memory capabilities eventually decline and the adaptive nature of these capabilities results in memory troubles. With the growth of the ageing population, new requirements and opportunities arise. In this talk, I introduce how we can augment memory in complex everyday situations through systems that are aware of our cognitive contexts and interfaces that integrate with our perceptions and behaviours. These systems sense cognitive contexts, such as cognitive load and visual recognition processes, using physiological signals (biosignals) and provide support by enhancing our memory through memory training and assisting with memory tasks. I will also describe our work to encourage user receptivity to these interventions, for example, using familiar AI-generated voices for reminders. This talk offers new perspectives and design insights on supporting our cognitive abilities and experiences.https://cassyni-user-files-prod.s3.amazonaws.com/6ingKYJp3j73y1R3rgWFM8 https://cassyni.com/slides/outline/SQ8SVwy37kkWToGzwCyecm https://cassyni.com/events/SQ8SVwy37kkWToGzwCyecm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/D1n5zubLrgAmvPYNE6hCA https://cassyni.com/events/SQ8SVwy37kkWToGzwCyecm?videoPreview=1 Unification in Pretabular Extensions of S4nohttps://cassyni.com/events/SQ8SVwy37kkWToGzwCyecm?videoPreview=12022-07-06T13:00:00+00:003020.76Logica UniversalisL.L. Maksimova and L. Esakia, V. Meskhi showed that the modal logic S4 has exactly 5 pretabular extensions PM1–PM5. In this paper, we study the problem of unification for all given logics. We showed that PM2 and PM3 have finitary, and PM1, PM4, PM5 have unitary types of unification. Complete sets of unifiers in logics are described.https://cassyni-user-files-prod.s3.amazonaws.com/D1n5zubLrgAmvPYNE6hCA https://cassyni.com/slides/outline/Stn3YdcZZDJZTZotXeGSt5 https://cassyni.com/events/Stn3YdcZZDJZTZotXeGSt5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6y7Uqt8aGTP48HJPCMCnLe https://cassyni.com/events/Stn3YdcZZDJZTZotXeGSt5?videoPreview=1 Can a Statistical Lung and Torso Shape Model Improve Respiratory Monitoring via Electrical Impedance Tomography?nohttps://cassyni.com/events/Stn3YdcZZDJZTZotXeGSt5?videoPreview=12022-08-16T04:00:00+00:002791.08The Auckland Bioengineering InstituteLung electrical impedance tomography (EIT) is a medical imaging technique to provide continuous, bedside monitoring of lung function during mechanical ventilation. The potential impact of EIT is particularly evident in the wake of the COVID-19 pandemic. To estimate conductivity changes in the chest associated with breathing, EIT typically requires assumptions about the underlying chest and/or lung shape of the patient. Prior knowledge of patient-specific lung shape and chest shape (e.g. from MRI or CT) has been shown to improve EIT accuracy. However, detailed shape information is often not available due to limited time or resources. Accordingly, our research evaluates whether statistical shape models can provide sufficient estimates of lung and torso shape to enhance EIT accuracy.https://cassyni-user-files-prod.s3.amazonaws.com/6y7Uqt8aGTP48HJPCMCnLe https://cassyni.com/events/DQ6We9uZjd62LwgYE5YBF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9djpM3qEQXjoDvo8F4tKeE https://cassyni.com/events/J1UGCWfdtfNvXTDXfdxcKf/seminar/qa https://cassyni.com/slides/outline/J1UGCWfdtfNvXTDXfdxcKf https://cassyni.com/events/J1UGCWfdtfNvXTDXfdxcKf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JkqvzwtvTybAYh2X1oxr6a https://cassyni.com/events/J1UGCWfdtfNvXTDXfdxcKf?videoPreview=1 Cell-specific cargo delivery using synthetic bacterial sporesnohttps://cassyni.com/events/J1UGCWfdtfNvXTDXfdxcKf?videoPreview=12024-11-11T13:00:00+00:00651.76National Institutes of HealthDelivery of cancer therapeutics to non-specific sites decreases treatment efficacy while increasing toxicity. In ovarian cancer, overexpression of the cell surface marker HER2, which several therapeutics target, relates to poor prognosis. We recently reported the assembly of biocompatible bacterial spore-like particles, termed ‘‘SSHELs.’’ Here, we modify SSHELs with an affibody directed against HER2 and load them with the chemo- therapeutic agent doxorubicin. Drug-loaded SSHELs reduce tumor growth and increase survival with lower toxicity in a mouse tumor xenograft model compared with free drug and with liposomal doxorubicin by preferentially accumulating in the tumor mass. Target cells actively internalize and then traffic bound SSHELs to acidic compartments, whereupon the cargo is released to the cytosol in a pH-dependent manner. We propose that SSHELs represent a versatile strategy for targeted drug delivery, especially in cancer settings.https://cassyni-user-files-prod.s3.amazonaws.com/JkqvzwtvTybAYh2X1oxr6a https://cassyni.com/slides/outline/GXXT4Tj4aHiG6jEQpDHCSh https://cassyni.com/events/GXXT4Tj4aHiG6jEQpDHCSh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Q86ih8xAjXxinwrQBsR9vW https://cassyni.com/events/GXXT4Tj4aHiG6jEQpDHCSh?videoPreview=1 A CADASIL NOTCH3 mutation leads to clonal hematopoiesis and expansion of Dnmt3a-R878H hematopoietic clonesnohttps://cassyni.com/events/GXXT4Tj4aHiG6jEQpDHCSh?videoPreview=12024-11-25T12:00:00+00:001256.04LeukemiaClonal hematopoiesis (CH) is nearly universal in the elderly. The molecular and cellular mechanisms driving CH and the clinical consequences of carrying clonally derived mutant mature blood cells are poorly understood. We recently identified a C223Y mutation in the extracellular domain (ECD) of NOTCH3 as a putative CH driver in mice. Provocatively, germline NOTCH3 ECD mutations perturbing cysteine numbers cause Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL), a type of vascular dementia, suggesting an unexpected link between CADASIL and CH. Here, we formally demonstrated that mouse hematopoietic stem and progenitor cells (HSPCs) expressing CADASIL-related NOTCH3C455R exhibit a proliferative advantage resulting in robust cellular expansion in vivo and in vitro. Co-expression of NOTCH3C455R and Dnmt3aR878H, homologous to a frequent human CH mutation, increased the fitness of NOTCH3C455R HSPCs, demonstrating their functional cooperation. Surprisingly, the presence of NOTCH3C455R hematopoietic cells supported the expansion of Dnmt3aR878H HSPCs in a non-cell autonomous fashion in vivo, strongly suggesting that CADASIL patients and asymptomatic carriers can be highly predisposed to DNMT3AR882H-driven CH. Considering that CADASIL-related NOTCH3 mutations are more frequent in the general population than anticipated (~1 carrier in 400 people), the effect of these NOTCH3 mutations on CH development should be considered.https://cassyni-user-files-prod.s3.amazonaws.com/Q86ih8xAjXxinwrQBsR9vW https://cassyni.com/slides/outline/MU1VXJCJxsFZZ9X6KJLZrV https://cassyni.com/events/MU1VXJCJxsFZZ9X6KJLZrV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3jmiqdXL1nWegxyjMxkN7g https://cassyni.com/events/MU1VXJCJxsFZZ9X6KJLZrV?videoPreview=1 Giant extrachromosomal element "Inocle" potentially expands the adaptive capacity of the human oral microbiomenohttps://cassyni.com/events/MU1VXJCJxsFZZ9X6KJLZrV?videoPreview=12024-12-04T02:00:00+00:00718.0Microbiome Virtual International ForumSurvival strategy of bacteria is expanded by extrachromosomal elements (ECEs). However, their genetic diversity and functional roles for adaptability are largely unknown. Here, we discovered a novel family of intracellular ECEs using 56 saliva samples by developing an efficient microbial DNA extraction method coupled with long-read metagenomics assembly. Even though this ECE family was not hitherto unidentified, our global prevalence analysis using 476 salivary metagenomic datasets elucidated that these ECEs reside in 74% of the population. These ECEs, which we named, “Inocles”, are giant plasmid-like circular genomic elements of 395 kb in length, having Streptococcus as a host bacterium. Inocles encode a series of genes that contribute to intracellular stress tolerance, such as oxidative stress and DNA damage, and cell wall biosynthesis and modification involved in the interactions with oral epithelial cells. Moreover, Inocles exhibited significant positive correlations with immune cells and proteins responding to microbial infection in peripheral blood. Intriguingly, we examined and found their marked reductions among 68 patients of head and neck cancers and colorectal cancers, suggesting its potential usage for a novel biomarker of gastrointestinal cancers. Our results suggest that Inocles potentially boost the adaptive capacity of host bacteria against various stressors in the oral environment.https://cassyni-user-files-prod.s3.amazonaws.com/3jmiqdXL1nWegxyjMxkN7g https://cassyni.com/slides/outline/TPscRPWGSSgHUCFRcGU3Xb https://cassyni.com/events/TPscRPWGSSgHUCFRcGU3Xb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/D87d4vGT5g6PVxfbaLSEaS https://cassyni.com/events/TPscRPWGSSgHUCFRcGU3Xb?videoPreview=1 Microbes in Spacenohttps://cassyni.com/events/TPscRPWGSSgHUCFRcGU3Xb?videoPreview=12025-03-18T10:00:00+00:001166.04Microbiome Virtual International ForumElucidating microbial behavior in space and its potential impact on future space exploration missions are critical. Microorganisms isolated from oligotrophic environments, such as the International Space Station (ISS), analogous habitat on Earth (Inflated Lunar/Mars Analog Habitat), and mission critical NASA assembly facilities, present unique adaptations to survive in nutrient-poor and high-stress conditions. These modifications offer important new perspectives on the evolution of microbial resistance in challenging environments. These include defense mechanisms against environmental stressors including radiation and microgravity, as well as systems for DNA repair and biofilm formation. One of the primary findings of the study is the identification of genes and proteins, such as oxidoreductases and mechanosensitive channels, which indicate convergent evolutionary strategies among diverse bacteria. Under these circumstances, with limited resources and confined space, some molecular traits allow bacteria to thrive. These adaptations are critical to our understanding of microbial survival and have far-reaching consequences for human health, biosecurity, and space habitat management. The tendency of these microorganisms to create biofilms and their ability to produce biomolecules with therapeutic applications (such as antioxidants and antibiotics) could affect the deterioration of spacecraft material and jeopardize structural integrity. This creates a twofold problem: long-term missions to Mars or beyond require careful management of the pathogenic potential of some microbes in order to protect astronaut health, even though some microbial products may be used for advantageous purposes (such as biomanufacturing or waste recycling in life support systems). By extending the knowledge gained in space microbiology research to other oligotrophic ecosystems on Earth, such polar deserts or marine systems, we can learn more about how life endures in hostile environments. The molecular insights gained from this study could also lead to new biotechnological applications, such the development of intelligent materials for space habitats or new antibacterial drugs to treat diseases. The study concludes by highlighting the role that bacteria play in establishing sustainable space exploration as well as the importance of microbial surveillance in enclosed settings.https://cassyni-user-files-prod.s3.amazonaws.com/D87d4vGT5g6PVxfbaLSEaS https://cassyni.com/slides/outline/KVUKZpdz1ktdA9jSrHVLwP https://cassyni.com/events/KVUKZpdz1ktdA9jSrHVLwP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JuaP9KbtNWscGDb7UZwci https://cassyni.com/events/KVUKZpdz1ktdA9jSrHVLwP?videoPreview=1 microbetag: simplifying microbial network interpretation through annotation, enrichment tests and metabolic complementarity analysisnohttps://cassyni.com/events/KVUKZpdz1ktdA9jSrHVLwP?videoPreview=12025-01-21T15:00:00+00:00464.16Microbiome Virtual International ForumMicrobial co-occurrence network inference is often hindered by low accuracy and tool dependency. Building on the reverse-ecology paradigm, we applied data integration and metabolic modeling methods to address these challenges. We introduce microbetag (https://hariszaf.github.io/microbetag/), a comprehensive software ecosystem designed to enhance network annotation. Nodes (taxa) are enriched with phenotypic traits, based on genome and literature knowledge, while edges represent two types of metabolic complementarities, highlighting potential cross-feeding relationships. Pathway complementarities are inferred from genome annotations, based on a donor species' ability to complete a missing step in a beneficiary's KEGG module. Seed complementarities, on the other hand, are derived from the metabolites a species requires exogenously, as determined by its metabolic model, and the donor's ability to produce these metabolites. microbetag’s online version relies on microbetagDB, a database of 34,608 high-quality genomes with detailed annotations. It effectively identified known metabolic interactions on previously published data. A preprocessing module allows the analysis of large data sets, while a stand-alone version allows users to apply microbetag to custom reference genomes/bins/MAGs. Ultimately, MGG, a CytoscapeApp we developed, offers a streamlined, user-friendly interface for retrieving and visualizing microbetag-annotated networks. Combined with network clustering and enrichment analysis, microbetag serves as a robust hypothesis-generating tool.https://cassyni-user-files-prod.s3.amazonaws.com/JuaP9KbtNWscGDb7UZwci https://cassyni.com/slides/outline/F3cG33JNfGyeZ2HFf4nLAH https://cassyni.com/events/F3cG33JNfGyeZ2HFf4nLAH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/57xqtMuX9yU7ifEsbHNebp https://cassyni.com/events/F3cG33JNfGyeZ2HFf4nLAH?videoPreview=1 Future Of Peer Reviewnohttps://cassyni.com/events/F3cG33JNfGyeZ2HFf4nLAH?videoPreview=12023-05-18T03:00:00+00:006171.24UKRNPeer review remains the primary means by which we ensure the quality of research grants and outputs. However, no system is perfect. Peer review could be improved, and there are different schools of thought on how this could be achieved. This event – hosted jointly by UKRN and the Research on Research Institute (RoRI) – will include a series of talks that outline approaches that, in part, reflect these different schools of thought. A panel discussion will enable participants and speakers to explore the commonalities, differences and implications of these approaches.https://cassyni-user-files-prod.s3.amazonaws.com/57xqtMuX9yU7ifEsbHNebp https://cassyni.com/slides/outline/9cUcXXBbqEtaAA3249nYAq https://cassyni.com/events/9cUcXXBbqEtaAA3249nYAq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LgMkjGGfaXyWvShmXHth6e https://cassyni.com/events/9cUcXXBbqEtaAA3249nYAq?videoPreview=1 The Role Of Metrology In Improving Reproducibilitynohttps://cassyni.com/events/9cUcXXBbqEtaAA3249nYAq?videoPreview=12021-10-06T03:00:00+00:006633.68UKRNProf. Richard Brown explains how metrology, the science of measurement, assures confidence in billions of physical measurements are made and used every day to support industry, trade, innovation and health – in fact just about all of human life – and how the system of measurements we rely on for physical measurements recently underwent fundamental change. Prof. Ian Gilmore focuses on the role of metrology in research and development. Louise Wright gives a short overview of how digital approaches can help to improve reproducibility.https://cassyni-user-files-prod.s3.amazonaws.com/LgMkjGGfaXyWvShmXHth6e https://cassyni.com/slides/outline/MxiLoEscD3fACJyEK5Hhwb https://cassyni.com/events/MxiLoEscD3fACJyEK5Hhwb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VHFvT1exGfZYnz2K5fSBo4 https://cassyni.com/events/MxiLoEscD3fACJyEK5Hhwb?videoPreview=1 Wild fish use visual cues to recognise individual diversnohttps://cassyni.com/events/MxiLoEscD3fACJyEK5Hhwb?videoPreview=12025-01-31T11:00:00+00:001496.88Royal Society PublishingMany animal species have been shown to discriminate between individual humans in captive settings and may use a variety of cues to do so. Empirical evidence remains scarce for animals in the wild however, particularly in aquatic contexts. For the first time, we investigated discrimination of individual humans by fish in the wild. We first trained two species of fish, saddled sea bream *Oblada melanura* and black sea bream *Spondyliosoma cantharus*, to follow a human diver to obtain a food reward. We then investigated whether they could discriminate between two human divers and follow the correct one in an operant conditioning paradigm. We show that both species were able to quickly learn to discriminate between the two divers when they wore different diving gear. However, they showed no preference when both divers wore identical gear, suggesting that discrimination is based predominantly on visual cues from the dive gear. We discuss the implications of these results for ethical considerations and research practices.https://cassyni-user-files-prod.s3.amazonaws.com/VHFvT1exGfZYnz2K5fSBo4 https://cassyni.com/slides/outline/SuCPG5LrbdCTejFupAM5MP https://cassyni.com/events/SuCPG5LrbdCTejFupAM5MP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9Na9jTeZNEJ1AH5bJqZBh8 https://cassyni.com/events/SuCPG5LrbdCTejFupAM5MP?videoPreview=1 How individuals seeking help for substance use disorder adjusted to virtual 12-step meetings during the COVID-19 pandemicnohttps://cassyni.com/events/SuCPG5LrbdCTejFupAM5MP?videoPreview=12025-02-12T16:00:00+00:00591.68Sage Publishing**INTRODUCTION**: Technology-based online support services are emerging as a resource for people recovering from substance abuse. This study presents findings on how individuals seeking help for a substance use disorder through 12-step fellowship meetings (Alcoholics Anonymous, Narcotics Anonymous) adjusted to virtual rather than in-person meetings during the COVID-19 pandemic. **METHOD**: Fifty individuals (50) were interviewed, recruited primarily from 12-step meetings in three locations in a rural New England state in the United States. Subjects were asked about whether they had attended virtual meetings during the pandemic, how online meetings compare to in-person meetings, and if they encountered any obstacles when attending virtual meetings (e.g., Internet connectivity). **RESULTS**: More individuals preferred in-person meetings for a variety of reasons, although many participants were willing to give virtual meetings a try. Some participants continued to attend virtual meetings, even after in-person meetings returned. Positives of virtual recovery meetings included convenience and the fact that they could be accessed from anywhere. Internet connectivity and technical difficulties presented a challenge for some. Some individuals were unable to focus in virtual meetings and got easily distracted. **CONCLUSION**: Digital recovery support services should continue to be offered as some recovering individuals find them helpful. Virtual meetings are a resource, particularly for those individuals living in rural areas without many in-person resources readily available, or access to adequate transportation. Treatment providers working in rural states may consider advocating to policymakers for quality Internet services (e.g., high-speed broadband access), to sufficiently meet residents’ treatment and other healthcare needs. https://cassyni-user-files-prod.s3.amazonaws.com/9Na9jTeZNEJ1AH5bJqZBh8 https://cassyni.com/slides/outline/ghp574tfsiJdz8mdoLCbf https://cassyni.com/events/ghp574tfsiJdz8mdoLCbf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BSpAM1RMkCFEYSu9TQvcfY https://cassyni.com/events/ghp574tfsiJdz8mdoLCbf?videoPreview=1 MHIT36: A Phase-Field Code for GPU Simulations of Multiphase Homogeneous Isotropic Turbulencenohttps://cassyni.com/events/ghp574tfsiJdz8mdoLCbf?videoPreview=12025-09-24T09:00:00+00:001348.36Computer Physics CommunicationsWe present MHIT36, a GPU-tailored solver for interface-resolved simulations of multiphase turbulence. The framework couples direct numerical simulation (DNS) of the Navier–Stokes equations, which describe the flow field, with a phase-field method to capture interfacial phenomena. Simulations are performed in a cubic domain with periodic boundary conditions applied in all three spatial directions. The governing equations are discretized using a second-order finite difference scheme. The Navier–Stokes equations are integrated with an explicit fractional-step method, and the resulting pressure Poisson equation is solved using a fast Fourier transform (FFT)-based approach. The accurate conservative diffuse interface (ACDI) formulation is used to describe the transport of the phase-field variable. From a computational standpoint, MHIT36 employs a two-dimensional domain decomposition to distribute the workload across MPI tasks. The cuDecomp library is used to perform pencil transpositions and halo exchanges, while the cuFFT library and OpenACC directives are leveraged to offload the remaining computational kernels to the GPU. This parallelization strategy enables MHIT36 to achieve an excellent scaling efficiency on 1024 GPUs, while maintaining a structure that is easy to extend and modify. MHIT36 is released open source under the MIT license.https://cassyni-user-files-prod.s3.amazonaws.com/BSpAM1RMkCFEYSu9TQvcfY https://cassyni.com/slides/outline/E2uvECF1eKZAXfNac9tvjo https://cassyni.com/events/E2uvECF1eKZAXfNac9tvjo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Jp3oVuYYqUbuKr225icW2A https://cassyni.com/events/E2uvECF1eKZAXfNac9tvjo?videoPreview=1 Quantum Phases Beyond Classical Shadows: A New Framework for Gravitational Wave Effectsnohttps://cassyni.com/events/E2uvECF1eKZAXfNac9tvjo?videoPreview=12025-09-19T11:00:00+00:002181.76Cassyni SeminarsIn this talk, I show how low-frequency gravitational waves can leave purely quantum fingerprints in mesoscopic optomechanical systems. Unlike classical or Berry phases, these are genuinely quantum, with no classical analogue. The waves couple to a tiny mechanical mirror, generating unique phase shifts in its quantum state. I propose a Ramsey-type interferometer where the mirror becomes entangled with photon number states, enabling a direct readout of the gravitational-wave–induced quantum phase. This opens a new quantum route to probe low-frequency gravitational waves, beyond conventional strain-based detection. https://cassyni-user-files-prod.s3.amazonaws.com/Jp3oVuYYqUbuKr225icW2A https://cassyni.com/events/MwLqCPdBUNGYzVAocYRQBo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HGibb6VJcetdTh5ssSnB9G https://cassyni.com/events/2BQfM3kBv47uHTAkbQtfuw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/H9vemWMna14Bkwq3TQMg94 https://cassyni.com/events/58xpFbShiUKit8EYLtDU6Z/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Kvseo42VvMJ28vMf5buX66 https://cassyni.com/events/5de3Quc7ZHoYhbE48zLSGm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Fttt3N83NPH79M3q4PufJE https://cassyni.com/slides/outline/FWc8LaYcLSssZ7E5eZ6oQh https://cassyni.com/events/FWc8LaYcLSssZ7E5eZ6oQh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Ejkhr3Ea37U6m3FypUe1yQ https://cassyni.com/events/FWc8LaYcLSssZ7E5eZ6oQh?videoPreview=1 Wide-ranging, year-round breaching behaviour of basking sharks revealed by long-term biologging nohttps://cassyni.com/events/FWc8LaYcLSssZ7E5eZ6oQh?videoPreview=12026-04-20T11:29:15+00:001772.44Royal Society PublishingMarine megafauna, including various species of cetaceans and fishes, exhibit energetically costly breaching behaviour during which individuals rapidly propel themselves out of the water. The function of breaching remains enigmatic, largely due to short duration observations of limited spatial extent. Here, we used animal-borne biologgers to record breaching events of plankton-feeding basking sharks (Cetorhinus maximus) over full annual cycles at high temporal resolution (5 s) across broad spatial scales (35° latitude). Recording 577 breaches across four individuals over 366 days (mean 144 yr⁻¹ shark⁻¹), breaching appears to be a routine behaviour in both sexes, peaking in autumn, but occurring across all seasons and habitats, including deep oceanic areas. Notably, we identified thermal constraints on breaching rates in colder water, with a critical minimum observed at 5°C. Beyond demonstrating that breaching is more common than previously recognised, our study suggests it serves several functions, some potentially independent of spatial and temporal contexts (e.g., seasonal courtship), such as ectoparasite removal. The ubiquity of breaching across space and time highlights the need for comprehensive ‘behaviour maps’ for ocean giants to elucidate the physiological constraints, ecological significance, and management implications of breaching in a changing ocean.https://cassyni-user-files-prod.s3.amazonaws.com/Ejkhr3Ea37U6m3FypUe1yQ https://cassyni.com/slides/outline/9682WS71pmq9XJzpTRs54q https://cassyni.com/events/9682WS71pmq9XJzpTRs54q/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UjZU3g1EsJXWtTEnL7oPiE https://cassyni.com/events/9682WS71pmq9XJzpTRs54q?videoPreview=1 Dissecting social contingency in vocal development using a robotic tutornohttps://cassyni.com/events/9682WS71pmq9XJzpTRs54q?videoPreview=12026-03-14T23:00:00+00:00457.96Royal Society PublishingIn humans and other animals, social robots can serve as effective tutors for learning new skills. Young oscines learn their song by imitating conspecific adults. In a previous study, we demonstrated that a robotic bird can be as effective as a live tutor in training a young zebra finch (Taeniopygia guttata) to imitate a song model. Here we take this further by investigating the role of behavioural contingency in developmental song learning and in shaping the birds’ engagement with the robot. Two group of young male finches were exposed to a robotic tutor under contingent (CON) or non-contingent (NCON) conditions. In the CON-group, the robot produced a call in response to a call emitted by the bird. When the bird perched nearby, the robot oriented toward it and broadcast a song. While song imitation was slightly better in the CON-group, the difference was not statistically significant. However, birds in the CON group spent more time near the robot and interacted with it more frequently compared to NCON-birds. These findings highlight the importance of behavioural contingency in social robotics and offer novel insights into the use of robotic agents in studies with non-human animals.https://cassyni-user-files-prod.s3.amazonaws.com/UjZU3g1EsJXWtTEnL7oPiE https://cassyni.com/slides/outline/VLjRX69RDuTd3ozPGfWmWu https://cassyni.com/events/VLjRX69RDuTd3ozPGfWmWu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/22Ua4VKByfDSHnTDRkMsDG https://cassyni.com/events/VLjRX69RDuTd3ozPGfWmWu?videoPreview=1 Bridging Electrochemical Models and Real-Time Battery Controlnohttps://cassyni.com/events/VLjRX69RDuTd3ozPGfWmWu?videoPreview=12026-03-05T19:00:00+00:00906.2Computer Physics CommunicationsWith the shift to low-carbon energy and advances in storage technologies, high-fidelity electrochemical models of lithium-ion batteries are increasingly needed. This paper presents an open-source implementation of the Control-oriented Parameter-Grouped Single Particle Model with Thermal effects (CPG-SPMT), which achieves a balance between model fidelity and computational efficiency. The model employs a parabolic approximation to discretize solid-phase diffusion using two states per electrode and applies parameter grouping to reduce the number of independent parameters without compromising physical interpretability. A thermal sub-model with Arrhenius-type temperature dependence is integrated to account for heat generation and dissipation effects. The model is expressed in explicit state-space form, supporting applications in observer design and predictive control. Comprehensive validation is conducted using A123 18,650 lithium iron phosphate cell data across eight ambient temperatures (-10 ∘C to 50 ∘C) and three driving profiles (DST, US06, FUDS), yielding 24 operating conditions. The model achieves an average root mean square error (RMSE) of 0.033 V, mean absolute error (MAE) of 0.022 V, demonstrating high prediction accuracy. The full codebase, validation scripts, and dataset are publicly released to facilitate further research in battery modeling, parameter identification, and real-time BMS control implementation.https://cassyni-user-files-prod.s3.amazonaws.com/22Ua4VKByfDSHnTDRkMsDG https://cassyni.com/events/Ky5tPDDiYsAt3xmL3NMGMj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/22HJmvX3rFAhdFpzEQauNN https://cassyni.com/events/5dn9z4BYa6SBSHHuXfdyf3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VfvJsadqkHMyLCtU2xncBQ https://cassyni.com/slides/outline/D3N77AJz9A7PCAkX6sCAgm https://cassyni.com/events/D3N77AJz9A7PCAkX6sCAgm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PXKVB2Bmx9iey9gHJ82ZiW https://cassyni.com/events/D3N77AJz9A7PCAkX6sCAgm?videoPreview=1 Meta-Radiology • Imaging Exploration Lecture Series • Brain-Computer Interface Technologynohttps://cassyni.com/events/D3N77AJz9A7PCAkX6sCAgm?videoPreview=12026-03-24T01:00:00+00:003380.56None♾️ Date: Mar. 24, 2026 ♾️ Speaker: Yong Lu, Prof. Shanghai Jiao Tong University School of Medicine ♾️ Major Research: Innovative Magnetic Resonance Technologies and Clinical Applications of Brain-Computer Interfaceshttps://cassyni-user-files-prod.s3.amazonaws.com/PXKVB2Bmx9iey9gHJ82ZiW https://cassyni.com/events/3AReJ7tNmMxnV8StssNFBT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JwHshxfA8E9eZMVVvd7tva https://cassyni.com/slides/outline/Wpm712dekMu6WWYmcpV1Gh https://cassyni.com/events/Wpm712dekMu6WWYmcpV1Gh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/ErQYToWTiSAcwVGodu96XY https://cassyni.com/events/Wpm712dekMu6WWYmcpV1Gh?videoPreview=1 The Heisenberg-Weyl-parity group as solvable group and a unified Wigner-Weyl functionnohttps://cassyni.com/events/Wpm712dekMu6WWYmcpV1Gh?videoPreview=12026-05-29T09:00:00+00:001754.64Annals of PhysicsThe Heisenberg-Weyl group $HW(d)$ related to a $d$-dimensional Hilbert space $H(d)$, is enlarged into the Heisenberg-Weyl-parity group $HWP(d)$ that incorporates parity transformations. It consists of $2d^3$ elements, of which $d^3$ elements belong to the $HW(d)$ subgroup, and extra $d^3$ elements which are related through a Fourier transform with the former ones. It is shown that $HWP(d)$ is a generalised version of the dihedral group. The properties of operators that combine displacements and parity, are discussed. $HWP(d)$ is shown to be a solvable group, and commutators of its elements perform displacement and parity transformations of quantum states, along loops in the discrete phase space. $2d^2$ coherent states related to the $HWP(d)$ group are introduced, which consist of $d^2$ coherent states related to the $HW(d)$ subgroup, and extra $d^2$ coherent states which are related through a Fourier transform with the former ones. In noisy cases, expansion of an arbitrary state in terms of the $2d^2$ coherent states with Bargmann coefficients, is advantageous in comparison to expansion in terms of the $d^2$ coherent states related to $HW(d)$. One of the consequences of the $HWP(d)$ group, is a natural unification of the Wigner and Weyl functions. The properties of the unified Wigner-Weyl function are discussed.https://cassyni-user-files-prod.s3.amazonaws.com/ErQYToWTiSAcwVGodu96XY https://cassyni.com/slides/outline/68LtgrHQoUD9M4G36btub3 https://cassyni.com/events/68LtgrHQoUD9M4G36btub3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/URZoe1XPAW6Wafu1ThUsWE https://cassyni.com/events/68LtgrHQoUD9M4G36btub3?videoPreview=1 The tensionless lives of null stringsnohttps://cassyni.com/events/68LtgrHQoUD9M4G36btub3?videoPreview=12026-05-22T09:00:00+00:002151.12Physics ReportsI will review the construction of the tensionless limit of string theory, focusing on the work in the last decade. This limit is the diametrically opposite limit of the much more well studied point particle limit, where the length of the fundamental string, instead of shrinking to zero, becomes infinite. The limit is a gateway to the ultra-high energy, ultra-"stringy" sector of string theory. I will discuss the intrinsic formulation of classical tensionless strings based on work by Isberg et al and then how one can understand this in terms of a Carrollian limit on the worldsheet which transforms the residual symmetries from two copies of the Virasoro algebra to the 2d Conformal Carroll algebra indicating that the worldsheet has become a null surface. The classical and quantum aspects of the null tensionless string would be discussed in detail. While the classical strings can be arrived at from both the intrinsic and limiting perspectives, the quantum null strings hold a variety of surprises. https://cassyni-user-files-prod.s3.amazonaws.com/URZoe1XPAW6Wafu1ThUsWE https://cassyni.com/events/BrrE1pAQtg7wxYh68Buru/abstract https://cassyni-user-files-prod.s3.amazonaws.com/R5MCzzMk5CdQkxVKBjVVJN https://cassyni.com/events/LTB39JZWw7CSohiFoPNHW5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/K4TGy8a3EbHfybpH41R2ZU https://cassyni.com/events/77fitr6M5kF2AHnSV9Jg2Z/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EGRNAwohXcT9wCyQ9KV6tW https://cassyni.com/events/QQR7k2mVFVUgUZTxSphP81/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Lzx7ZnCx4NSwd1MTJqdWpe https://cassyni.com/events/F2EkSC3wvbb3MCUpxXv2QV/seminar/qa https://cassyni.com/slides/outline/F2EkSC3wvbb3MCUpxXv2QV https://cassyni.com/events/F2EkSC3wvbb3MCUpxXv2QV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Fuw5TjCwRawuoDGEMc83DQ https://cassyni.com/events/F2EkSC3wvbb3MCUpxXv2QV?videoPreview=1 Celebrating Professor George Barany's Half Century in Sciencenohttps://cassyni.com/events/F2EkSC3wvbb3MCUpxXv2QV?videoPreview=12025-10-28T16:00:00+00:006276.36International Journal of Peptide Research and TherapeuticsThis seminar commemorates Professor George Barany’s five decades of contributions to peptide chemistry and related biomedical sciences, highlighting his pioneering work in orthogonal solid-phase peptide synthesis and its impact on protein folding, peptide therapeutics, and diabetes research. The presentations emphasize the integration of peptide synthesis with biophysical and biochemical analyses to elucidate protein folding pathways, exemplified by studies on bovine pancreatic trypsin inhibitor (BPTI). Barany’s synthetic strategies enabled the creation of site-specific analogs that revealed the folding core and partially folded intermediates, providing foundational insights into intrinsically disordered proteins (IDPs) and their functional ensembles. Advances in chemical synthesis facilitated the production of complex peptides and insulin analogs, overcoming challenges in folding efficiency and enabling industrial-scale manufacture of therapeutic proteins such as insulin and its derivatives. The seminar also addresses the application of native chemical ligation to generate clinical proinsulin variants, illuminating the molecular basis of toxic misfolding in monogenic diabetes syndromes and correlating folding efficiency with disease onset. Further, the development of novel peptide ligands targeting G-protein-coupled receptors (GPCRs) in neuroscience exemplifies the ongoing expansion of peptide-based drug discovery. Barany’s introduction of orthogonality in protecting group chemistry revolutionized peptide synthesis, allowing selective manipulations essential for complex molecule assembly. The collective work underscores the enduring significance of rigorous synthetic methodology combined with biophysical characterization in advancing peptide science, therapeutic innovation, and understanding of protein folding diseases, while also reflecting on mentorship, interdisciplinary collaboration, and the evolving landscape of macromolecular medicines.https://cassyni-user-files-prod.s3.amazonaws.com/Fuw5TjCwRawuoDGEMc83DQ https://cassyni.com/slides/outline/NTFTPQTb34WMH5ttiW78jX https://cassyni.com/events/NTFTPQTb34WMH5ttiW78jX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3pr4fBayAyFc9CXELgbXRQ https://cassyni.com/events/NTFTPQTb34WMH5ttiW78jX?videoPreview=1 Longitudinal analysis of the gut microbiome in adolescent patients with anorexia nervosa: microbiome-related factors associated with clinical outcomenohttps://cassyni.com/events/NTFTPQTb34WMH5ttiW78jX?videoPreview=12024-09-17T14:00:00+00:00596.0Microbiome Virtual International ForumThere is mounting evidence regarding the role of gut microbiota in anorexia nervosa (AN). Previous studies have reported that patients with AN show dysbiosis compared to healthy controls (HCs), however, the underlying mechanisms are unclear, and data on influencing factors and longitudinal course of microbiome changes are scarce. Here, we present longitudinal data of 57 adolescent inpatients diagnosed with AN at up to nine time points (including a 1-year follow-up examination) and compare these to up to six time points in 34 HCs. 16S rRNA gene sequencing was used to investigate the microbiome composition of fecal samples, and data on food intake, weight change, hormonal recovery (leptin levels), and clinical outcomes were recorded. Differences in microbiome composition compared to HCs were greatest during acute starvation and in the low-weight group, while diminishing with weight gain and especially weight recovery at the 1-year follow-up. Illness duration and prior weight loss were strongly associated with microbiome composition at hospital admission, whereas microbial changes during treatment were associated with kilocalories consumed, weight gain, and hormonal recovery. The microbiome at admission was prognostic for hospital readmission, and a higher abundance of Sutterella was associated with a higher body weight at the 1-year follow-up. Identifying these clinically important factors further underlines the potential relevance of gut microbial changes and may help elucidate the underlying pathophysiology of gut-brain interactions in AN. The characterization of prognostically relevant taxa could be useful to stratify patients at admission and to potentially identify candidate taxa for future supplementation studies aimed at improving AN treatment.https://cassyni-user-files-prod.s3.amazonaws.com/3pr4fBayAyFc9CXELgbXRQ