https://cassyni.com/events/Np9amhNcuaU7nt4R9TzrL5/seminar/qa https://cassyni.com/slides/outline/Np9amhNcuaU7nt4R9TzrL5 https://cassyni.com/events/Np9amhNcuaU7nt4R9TzrL5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6myecfcEfuiNq1HKd4Ddsk https://cassyni.com/events/Np9amhNcuaU7nt4R9TzrL5?videoPreview=1 Applications of Conditional Spectral Analysis to Fluid Dynamicsnohttps://cassyni.com/events/Np9amhNcuaU7nt4R9TzrL5?videoPreview=12023-11-07T15:00:00+00:002888.64Experiments in FluidsThis presentation describes applications of conditional spectral analysis to fluid dynamics. In the first part, we describe a general noise-removal technique via a multiple-input, multiple-output (MIMO) framework capable of removing an arbitrary number of possibly coherent contaminating noise measurements, regardless of their order, from multiple sensor measurements. An application example to unsteady surface pressure measurements in an air wind tunnel is provided to demonstrate the technique. In the second part, we present spectral analysis modal methods (SAMMs) to perform POD in the frequency domain using non-time-resolved particle image velocity (PIV) data combined with unsteady surface pressure measurements. Here, time-resolved unsteady surface pressure measurements are synchronized with non-time-resolved planar PIV measurements acquired at 15 Hz in a Mach 0.6 cavity flow. Leveraging the spectral linear stochastic estimation (LSE) method of Tinney et al. (Exp Fluids 41:763–775, 2006), we first estimate the cross-correlations between the velocity field and the unsteady pressure sensors via sequential time shifts, followed by a Fast Fourier transform to obtain the pressure–velocity cross spectral density matrix. This leads to a linear multiple-input/multiple-output (MIMO) model that determines the optimal transfer functions between the input cavity wall pressure and the output velocity field.https://cassyni-user-files-prod.s3.amazonaws.com/6myecfcEfuiNq1HKd4Ddsk https://cassyni.com/events/71TVX5hbfebhkhp4mmoDg9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Pvs65avwxDdaNQpvqzibhG https://cassyni.com/events/DvPqbWBWoFirWpjnkY4cSZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FiPVi5z6siVcrkr2qW914a https://cassyni.com/events/JNFu8HX89jdq7xBywkmdDf/seminar/qa https://cassyni.com/slides/outline/JNFu8HX89jdq7xBywkmdDf https://cassyni.com/events/JNFu8HX89jdq7xBywkmdDf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/74uY4bXwSU29XmqgP88L54 https://cassyni.com/events/JNFu8HX89jdq7xBywkmdDf?videoPreview=1 Open Data & Springer Nature’s New Research Data Policynohttps://cassyni.com/events/JNFu8HX89jdq7xBywkmdDf?videoPreview=12023-05-17T15:00:00+00:002023.56Topics at the heart of our communityResearch Data are a key component of our open science strategy. We want the data underlying our publications to be as open as possible to the research community. In order to build our data handling and services, we must ensure our policies are clearly understood, actionable and in line with community expectations. Springer Nature’s new research data policy strives to embed transparency while improving support for authors and editors.https://cassyni-user-files-prod.s3.amazonaws.com/74uY4bXwSU29XmqgP88L54 https://cassyni.com/events/VEXC9KkfoopJeE21ZJ1KAV/seminar/qa https://cassyni.com/slides/outline/VEXC9KkfoopJeE21ZJ1KAV https://cassyni.com/events/VEXC9KkfoopJeE21ZJ1KAV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6Atr1ptUtR6fMY4u6nGTF4 https://cassyni.com/events/VEXC9KkfoopJeE21ZJ1KAV?videoPreview=1 Boolean functions and their use in symmetric cryptographynohttps://cassyni.com/events/VEXC9KkfoopJeE21ZJ1KAV?videoPreview=12023-06-07T15:00:00+00:003605.08The Journal of Algebraic CombinatoricsBoolean functions play a central role in the security of stream and block ciphers (in symmetric cryptography). They are functions mapping binary vectors of some length to either bits (in which case we have Boolean functions strictly speaking) or to binary vectors (of the same length or of another length, we are then speaking of vectorial Boolean functions). In the first case, they play roles in stream ciphers and in the second case, they are mainly used as substitution boxes in block ciphers. Being in each case the only nonlinear components of the ciphers, they are essential to their security. They are also the main components of the ciphers whose choice induces the speed. A tradeoff must then be found between the security and the speed of the cipher. The AES winner (used nowadays as a NIST standard for civil encryption, in particular between all banks) has been chosen because it allowed the best tradeoff. We shall describe what are the main results on them and what are the main open problems they pose currently. https://cassyni-user-files-prod.s3.amazonaws.com/6Atr1ptUtR6fMY4u6nGTF4 https://cassyni.com/slides/outline/XhnqVNWBQTWZqAY3GVMT2V https://cassyni.com/events/XhnqVNWBQTWZqAY3GVMT2V/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HdsrWqs4jmLnxSTdikSFie https://cassyni.com/events/XhnqVNWBQTWZqAY3GVMT2V?videoPreview=1 Design Across Layers: Achieving More by Joining Hardware, Software, and Cryptographynohttps://cassyni.com/events/XhnqVNWBQTWZqAY3GVMT2V?videoPreview=12023-09-11T11:00:00+00:001935.68HiPEDS CentreModern computer systems are built out of many different layers: protocols, software, and hardware all work together to make a larger system. Developers use each layer to build the next layer above it. Security engineers can incorporate defences at different layers. Each layer has its own limitations: cryptography can’t be trusted if the software implementing it is vulnerable, and hardware can’t change to adapt to new situations. By combining primitives from different layers, we can produce security mechanisms that are more than the sum of their parts. In this talk, we will show how cryptographic techniques, embedded into software, can protect against memory corruption attacks, and demonstrate how this can protect the return address stack and user data structures even in a vulnerable program. https://cassyni-user-files-prod.s3.amazonaws.com/HdsrWqs4jmLnxSTdikSFie https://cassyni.com/slides/outline/HsafxyMiJvA1JVCU9eef3T https://cassyni.com/events/HsafxyMiJvA1JVCU9eef3T/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JSbfvwVtnQKLApwzKY6GB8 https://cassyni.com/events/HsafxyMiJvA1JVCU9eef3T?videoPreview=1 Turbulence is Everywhere! Examples of Turbulence and Canonical Flowsnohttps://cassyni.com/events/HsafxyMiJvA1JVCU9eef3T?videoPreview=12021-03-26T12:00:00+00:001475.72Brunton LabTurbulence is one of the most interesting and ubiquitous phenomena in fluid dynamics. In this video, we explore several examples of canonical and real world turbulent fluids, with engineering applications.https://cassyni-user-files-prod.s3.amazonaws.com/JSbfvwVtnQKLApwzKY6GB8 https://cassyni.com/events/4Y8bwmvKGH45dZ1XHUxzLd/seminar/qa https://cassyni.com/slides/outline/4Y8bwmvKGH45dZ1XHUxzLd https://cassyni.com/events/4Y8bwmvKGH45dZ1XHUxzLd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/66MJAJHrWEyyKEJiXAX7EN https://cassyni.com/events/4Y8bwmvKGH45dZ1XHUxzLd?videoPreview=1 Temporal Image Forensics: What do we actually learn in data driven approaches ?nohttps://cassyni.com/events/4Y8bwmvKGH45dZ1XHUxzLd?videoPreview=12023-10-05T10:30:00+00:002975.84Journal on Image and Video ProcessingThe assessment of the age of a given digital image, assuming that the EXIF data is not trustworthy, has been traditionally done by analyzing sensor defects which occur and accumulate over time. In recent work, deep-learning based technology has been increasingly used for the age assessment task, which raises the question, which image features are actually used by such techniques. Moreover, (public) datasets used in corresponding experimentation might be prone to content bias, such that instead of age groups, actually content groups are created. We will report on recent results on this topic also showing the importance of XAI techniques in this field.https://cassyni-user-files-prod.s3.amazonaws.com/66MJAJHrWEyyKEJiXAX7EN https://cassyni.com/slides/outline/XD5zDRptAH6yBhW4JsnyiD https://cassyni.com/events/XD5zDRptAH6yBhW4JsnyiD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/F3H3kZE92gyXzPBSPKXfx2 https://cassyni.com/events/XD5zDRptAH6yBhW4JsnyiD?videoPreview=1 The “dark sight” and “bright side” of innovation: A study of paradoxes and tensions in creativity and innovationnohttps://cassyni.com/events/XD5zDRptAH6yBhW4JsnyiD?videoPreview=12023-02-09T00:30:00+00:003571.48Faculty of Business and EconomicsAlthough innovative teams are typically assumed to be successful teams, little is known about the process of innovation in teams that face stressful, demanding and/or unexpected conditions while carrying out their everyday operations. Although innovation may be required to cope with such conditions and the vast literature on organizational innovation certainly suggests that the more teams and individuals innovate the better, at the same time it might provoke further disruption and stress, leading to negative rather than beneficial outcomes for teams and individuals. In fact, innovation has been associated with increased uncertainty and complexity all of which may further increase the feelings of stress and ultimately lead to poorer rather than improved performance. These arguments are consistent with the literature on vicious circles in organizations which may emerge when actors fail to fully understand the complexity of the situation within which they are operating. Thus, interventions are made whose consequences are not understood, creating even more problems that demand attention. This talk will be based on a five-year program of research that has focused on studying small teams engaged in an intense simulation exercise that involves precision and time-critical tasks in an unpredictable environment. We explored to what extent the experience of stressors triggers teams to innovate and, in turn, what effects team innovation has on team performance and individual team member well-being. We put forward competing hypotheses suggesting both, beneficial and detrimental effects of stress-driven innovation as attempts to innovate in the face of unexpected events and emerging problems may help teams overcome these; however, it may also trigger the “vicious circle” effect, leading to poorer team performance and additional stress for team members. Our simulation-based research design with randomly allocated teams operating under the same environmental conditions can help us rule out alternative explanations for our results, such as the effects of past experience with the task, familiarity between team members and other contextual conditions on the relationship between innovation and team performance and individual team member well-being, respectively. We contribute to the literature on paradoxes and tensions in creativity and innovation by showing how stress-driven innovation is a paradoxical phenomenon that might be both beneficial and dysfunctional.https://cassyni-user-files-prod.s3.amazonaws.com/F3H3kZE92gyXzPBSPKXfx2 https://cassyni.com/slides/outline/TkYkteJD65ELA1CVfDR2BP https://cassyni.com/events/TkYkteJD65ELA1CVfDR2BP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5db4GigjxK4hdAcWo9s2Cn https://cassyni.com/events/TkYkteJD65ELA1CVfDR2BP?videoPreview=1 Pricing and funding with case mix modelsnohttps://cassyni.com/events/TkYkteJD65ELA1CVfDR2BP?videoPreview=12023-03-19T22:00:00+00:004833.96Faculty of Business and EconomicsThe aim of this workshop is to describe and explore current case mix costing systems in NZ and their use in funding. The workshop is designed to range from specifics (a cost system), through the process of compiling national case weights and their role in activity based funding, to a general perspective on these were used inside a District Health Board. The first speaker will describe the essential features of the Waitemata District cost system and how it relates to the National Common Costing Standards. The second speaker will explain the national system for calculating case weights and pricing them together with the determination of some specific price adjusters (e.g. the tertiary adjuster). Our third speaker will discuss what is activity based funding and how case mix fits into this together with some of the advantages of case mix in funding and decision making. Our fourth speaker will provide a historical perspective of how case mix was used in internal funding allocations and evaluation in a tertiary DHB. All four panellists have extensive experience in the New Zealand health sector and a detailed knowledge of case mix and funding at national and District levels. With the end of the population based funding model and the new health body, Te Whatu Ora, this workshop provides an essential foundation for considering different funding models for the New Zealand health sector. Consequently, it should be of interest to managers and clinicians in the healthcare sector, and especially for financial teams, business analysts and those providing consulting services to the sector. The discussion will be moderated by Prof Paul Rouse. Discussion topics: 1. Costing systems In TWO Districts - Description of Waitemata costing system and NZ common costing system 2. Compilation of case weights in NZ and base Price - The national system for calculating case weights, the price book and setting the base price 3. DRGs, case weights and funding - Activity based funding and the use of case weights for this 4. Use of DRGs and case weights in internal funding allocations and evaluation - Internal Hospital funding allocations and evaluation using DRGs and case weights (Historical Perspective of a DHB’s experience, 2007-2012). https://cassyni-user-files-prod.s3.amazonaws.com/5db4GigjxK4hdAcWo9s2Cn https://cassyni.com/events/PJpow1Y2kPwwcM3vwa7pWH/seminar/qa https://cassyni.com/slides/outline/PJpow1Y2kPwwcM3vwa7pWH https://cassyni.com/events/PJpow1Y2kPwwcM3vwa7pWH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/35Uid3g8G96oRFzVgQ5DEE https://cassyni.com/events/PJpow1Y2kPwwcM3vwa7pWH?videoPreview=1 Selectivity control in anodic gas evolving reactions on Ru based oxidesnohttps://cassyni.com/events/PJpow1Y2kPwwcM3vwa7pWH?videoPreview=12023-12-13T14:00:00+00:004015.12Electrochimica ActaEffective control of anodic gas evolving processes like, e.g. oxygen evolution and chlorine evolution is important from both fundamental as well as of applied point of view. The oxygen evolution process is of crucial importance in steering the water electrolysis needed for renewable energy storage. The chlorine evolution then is at core of chlor–alkali and chlorate applications. Both electrode processes take part at similar potentials and also are catalyzed by the same type of materials. It is generally known that kinetic hindrances of four electron oxygen evolution are not only limiting possible deployment of water electrolyzers in replacement of fossil fuels, but also are responsible for kinetic preference of chlorine evolution as prevailing anodic reaction in chloride containing solutions. An effective control of the catalyst selectivity in these competing reactions can be seen as the key enabler of the use of brackish or even sea water electrolytic hydrogen production. This workshop will discuss the selectivity tendencies of Ru based oxides in parallel chlorine and oxygen evolution reactions. on identification of key catalyst parameters needed to steer selectively gas evolving reaction on Ru oxides substituted with Mn and Ti prepared by the spray freeze freeze drying approach and their behavior in parallel oxygen and chlorine evolution reactions. The selectivity of these single phase materials with rutile structure based on RRDE and DEMS measurements will be rationalized in terms of chemical composition, local structure and prevailing mechanism of the oxygen evolving process. It will be shown that the overall electrocatalytic activity of Ru oxides increases with increasing content of the substituting transition metal. The increasing presence of Ti and Mn has, however an opposite effect on the selectivity. While the presence of Ti in substituted materials supports the selectivity towards CER the presence of Mn leads to an increase the selectivity towards oxygen evolution in acidic chloride containing solutions. The analysis of reaction orders for both competing reactions with respect to chloride concentration indicates that the overall selectivity is in fact controlled by the oxygen evolution process regardless of the chemical composition. The high selectivity towards oxygen evolution reaction coincides with low tendency of prepared phases to evolve oxygen via lattice oxygen activation (LOER). The experimental behaviour is further discussed from the theoretical point of view by DFT analysis of the reactivity of the Ru-Me-O surfaces where Me stands for Ti, Mn and Ni respectively. https://cassyni-user-files-prod.s3.amazonaws.com/35Uid3g8G96oRFzVgQ5DEE https://cassyni.com/events/WDuGaabNtohj7A3WK1gkey/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AdQDomMfripbRMMcxa7KTL https://cassyni.com/events/WiYsdGEuLGFn6vaPuSyYvH/seminar/qa https://cassyni.com/slides/outline/WiYsdGEuLGFn6vaPuSyYvH https://cassyni.com/events/WiYsdGEuLGFn6vaPuSyYvH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/T8D1CrsqzsA32uTHXYJHPC https://cassyni.com/events/WiYsdGEuLGFn6vaPuSyYvH?videoPreview=1 Additive Manufacturing in the Smart Factory: Challenges and Opportunities for Producibility, Enhanced Performance, and Sustainability in Aerospacenohttps://cassyni.com/events/WiYsdGEuLGFn6vaPuSyYvH?videoPreview=12024-03-26T17:00:00+00:003759.56AIAA JournalAdditive Manufacturing is an emerging technology that has the potential to significantly disrupt the Aerospace industry by creating innovative design solutions to difficult engineering problems. Benefits that drive Additive Manufacturing implementation include: increased vehicle performance due to novel part designs achievable only with additive manufacturing; reduced cost and schedule; and enhanced producibility and sustainability trades. A key prerequisite to onboarding additive manufacturing onto flight vehicles is demonstration of repeatable and reliable performance. This talk will discuss research aimed at achieving repeatable and reliable material characteristics and dimensional stability. Further, because Additive Manufacturing is a digital process, the end-to-end value stream can be readily integrated into the digital thread, where extracted data from each process in the value stream is archived in a cloud-based repository that is easily accessible for the creation of data driven models and machine learning algorithms that provide continuous improvement feedback, enhanced insight into the process, and drive scale and quality.https://cassyni-user-files-prod.s3.amazonaws.com/T8D1CrsqzsA32uTHXYJHPC https://cassyni.com/events/71KNww8Aeqy521kDP6VgHs/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RGv4eWTEVMjm9pvLLq6pcn https://cassyni.com/slides/outline/BT9pN5wtbxxKUfW1HkGFSM https://cassyni.com/events/BT9pN5wtbxxKUfW1HkGFSM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EU8CJWcvk9HVTf6x4VTtiz https://cassyni.com/events/BT9pN5wtbxxKUfW1HkGFSM?videoPreview=1 Building the cell from unreliable parts: the case of stochastic organelle biogenesisnohttps://cassyni.com/events/BT9pN5wtbxxKUfW1HkGFSM?videoPreview=12022-05-26T09:00:00+00:004181.8Journal of Biological PhysicsPerhaps the defining feature of the eukaryotic cell is its organization into membrane-bound compartments known as organelles. While the processes underlying the biogenesis of individual organelles are often well-known, the precision with which individual cells exert quantitative control over individual organelle properties, such as number and size, and coordinate these properties at systems-scale across the cell’s many different types of organelles remain frontier problems in cell biology and biophysics. Using a combination of theory and quantitative experiment, I will describe our recent efforts to show that cells exhibit substantial limits to the precision with which they can control organelle numbers and sizes, but despite this appear to collectively organize organelle biogenesis into specific “modes” when faced with the need to respond to environmental and genetic perturbations.https://cassyni-user-files-prod.s3.amazonaws.com/EU8CJWcvk9HVTf6x4VTtiz https://cassyni.com/slides/outline/PoPYdodtymiuWpSDYfmRD7 https://cassyni.com/events/PoPYdodtymiuWpSDYfmRD7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KhDTAPeaUgUVzoEzBTEj1G https://cassyni.com/events/PoPYdodtymiuWpSDYfmRD7?videoPreview=1 Real-world impact of bioengineeringnohttps://cassyni.com/events/PoPYdodtymiuWpSDYfmRD7?videoPreview=12022-11-30T14:00:00+00:005415.24Nature Reviews BioengineeringJoin the Chief Editor of Nature Reviews Bioengineering, Christine Horejs, and two esteemed panelists in the field of bioengineering, Robert Langer and Annie Moisan, as they discuss the real-world impact of bioengineering and the role this new journal will play in supporting scientists at all career stages with their research.https://cassyni-user-files-prod.s3.amazonaws.com/KhDTAPeaUgUVzoEzBTEj1G https://cassyni.com/events/TkgsTnse6srxthGM3tiZZf/seminar/qa https://cassyni.com/slides/outline/TkgsTnse6srxthGM3tiZZf https://cassyni.com/events/TkgsTnse6srxthGM3tiZZf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Au6RgUBBq54LaASrJ5oh1p https://cassyni.com/events/TkgsTnse6srxthGM3tiZZf?videoPreview=1 Hydrodynamics and shape reconstruction of single rising air bubbles in water using high-speed tomographic particle tracking velocimetry and 3D geometric reconstruction, Lensless Particle Image Velocimetrynohttps://cassyni.com/events/TkgsTnse6srxthGM3tiZZf?videoPreview=12024-05-07T14:00:00+00:003337.72Experiments in FluidsTime-resolved tomographic particle tracking velocimetry (TR-3D-PTV), also called 4D-PTV, is used here to obtain the instantaneous 3D liquid flow field information in the wake of a single rising bubble in water. Simultaneously the bubble shape, size and velocity are determined by tomographic reconstruction of the 3D bubble shape. Both, tracer particles for PTV and bubbles are imaged in a shadow mode with background illumination. The Lagrangian method used in this paper, especially combined with the shake the box algorithm (STB), has big advantages compared to particle image velocimetry (PIV), in situations, where only low particle per pixel (ppp) values can be obtained. In this research, single air bubbles of different sizes, with diameters of around 2.4 mm, 4.0 mm, 6.0 mm and 9.6 mm, were injected into stagnant de-ionized water. Their shape was reconstructed in 3D and an equivalent bubble diameter was determined from this reconstruction. Compared to conventionally used 2D shadow imaging, this diameter is about 13% smaller. The 3D bubble trajectory can be analysed and decomposed into a sinusoidal function curve lateral projection and an ellipsoidal shape vertical projection. As the bubble diameter increases, the radius of the spiral trajectory is decreasing, as well as the amplitude of vertical sinusoidal oscillation. The wake structure in the liquid behind the bubbles is also changing with bubble size: from simple vortex pairs for smaller bubbles, to an intertwined structure of several twisted vortices for the bigger ones. The application of lensless imaging to particle image velocimetry (PIV) is demonstrated. Lensless PIV eliminates the need for imaging lenses to measure flow fields near a surface. Only the camera sensor, a thin mask, and computations are required to image particles in a flow field and to compute the velocity field. The small form factor could enable embedded sensors for near-wall measurements. Flow field measurements are obtained simultaneously for a lensless system and lens-based 2D PIV system, and several different reconstruction techniques are demonstrated. The reconstructed particle images and computed velocity fields compare well for both a uniform and shear flow. The potential for stereo and 3D volumetric PIV with a single camera sensor is demonstrated through different image reconstruction approaches.https://cassyni-user-files-prod.s3.amazonaws.com/Au6RgUBBq54LaASrJ5oh1p https://cassyni.com/slides/outline/JruWAyAebCBt7iisYC4RUy https://cassyni.com/events/JruWAyAebCBt7iisYC4RUy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KMsDvyK8JqXbfJ9pRCCGni https://cassyni.com/events/JruWAyAebCBt7iisYC4RUy?videoPreview=1 Spectrally-Dispersed Kernel Phase Interferometry with SCExAO/CHARIS: Proof of Concept and Calibration Strategiesnohttps://cassyni.com/events/JruWAyAebCBt7iisYC4RUy?videoPreview=12023-05-31T09:00:00+00:001714.44Cassyni SeminarsDiscovering new actively-accreting protoplanets is crucial to answering open questions about planet formation. However, identifying such planets on true Solar System scales is technically challenging. The large distances to star-forming regions require moderate contrast at high angular resolutions which is difficult to achieve even with today's largest telescopes and extreme adaptive optics (AO) systems. Novel approaches are needed to process AO-corrected data to reach these planets. Kernel phase interferometry (KPI) is a data processing technique that allows for the detection of asymmetries arising from companions or disks in high-Strehl AO-corrected images, close to or beyond the classical diffraction limit of the telescope. KPI allows us to access a region of parameter space interior to current direct imaging studies using coronagraphy, where planet formation is thought to be more efficient. Here I will present results from a program which validates the use of KPI with the SCExAO/CHARIS instrument on the Subaru telescope. As well as demonstrating KPI and characterising SCExAO/CHARIS for future observations with the technique, I will also present a search for signs of Br-gamma accretion around multiple young stars with candidate protoplanets.https://cassyni-user-files-prod.s3.amazonaws.com/KMsDvyK8JqXbfJ9pRCCGni https://cassyni.com/slides/outline/52kasq3xJNgQUYGAdWi1k9 https://cassyni.com/events/52kasq3xJNgQUYGAdWi1k9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/81k139FS3RaVq4vghxQLWS https://cassyni.com/events/52kasq3xJNgQUYGAdWi1k9?videoPreview=1 Co-optimising Frequency-Containment Services from Zero-Carbon Sources in Electricity Grids Dominated by Renewable Energy Sourcesnohttps://cassyni.com/events/52kasq3xJNgQUYGAdWi1k9?videoPreview=12023-07-31T13:00:00+00:00568.52Imperial College London Early Career Researcher InstitutePower systems dominated by Renewable Energy Sources (RES) are characterised by reduced levels of inertia, which in turn threat the security of the electricity grid, and significantly increase the requirement for ancillary services such as inertia and Frequency Response (FR). Since inertia and FR are typically provided by part-loaded thermal generators, system security and carbon emissions are still highly coupled. Therefore, it becomes critical to investigate alternative ways to guarantee grid stability without resorting to polluting assets, as emissions targets would be unattainable otherwise. In this context, the present paper introduces a frequency-secured Stochastic Unit Commitment (SUC) model, which simultaneously co-optimises clean services such as inertia from Synchronous Condensers (SCs) and FR from part-loaded RES. A methodology is proposed to capture the dynamics for inertia from SCs and FR from RES in the form of linear constraints. The ancillary services dynamics are then mapped into the optimisation through frequency-security constraints obtained by solving the swing equation, eventually formulated as a Mixed-Integer Second-Order Cone Program (MISOCP). The proposed constraints enforce that sufficient ancillary services are scheduled to keep system stability, while taking advantage of the economic savings and emissions reduction from zero-carbon sources. Finally, to provide a rigorous quantification of the benefits of co-optimising the provision of zero-carbon ancillary services, a 2030 Great Britain (GB) power system scenario is used, demonstrating that ancillary services cost can be reduced from 45% to 4.2% of total system operating cost, and the emissions due to stability actions can be reduced from 57% to 2.6% of total system emissions.https://cassyni-user-files-prod.s3.amazonaws.com/81k139FS3RaVq4vghxQLWS https://cassyni.com/events/6WotUQ45EC3ekwHBBLWRQq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HsnKh4gLZZDk9YVzUXHmqG https://cassyni.com/slides/outline/MppkZhZgdJSEyeY1kvb5tZ https://cassyni.com/events/MppkZhZgdJSEyeY1kvb5tZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LA4FP3UwaTssRJkSgysBSW https://cassyni.com/events/MppkZhZgdJSEyeY1kvb5tZ?videoPreview=1 The Energy Spreading PONS Transform and its Applicationsnohttps://cassyni.com/events/MppkZhZgdJSEyeY1kvb5tZ?videoPreview=12023-07-13T18:00:00+00:002906.48Journal of Mathematical SciencesPONS, the Prometheus Orthonormal Set, is a suite of digital signal processing and data transmission algorithms whose genesis is found in a generalization of the Shapiro Polynomials. We begin with an overview of the mathematical and energy spreading features of PONS and then discuss a "Global Uncertainty Principle", which was the initial motivation for the PONS construction. Then we describe the elementary yet elegant construction by Harold Shapiro of his polynomials, and show the straightforward generalization of this construction which yields the PONS sequences and polynomials. After briefly comparing PONS with the Walsh Functions we outline possible mathematical interpretations of Energy Spreading. We conclude with a live demonstration showing the extreme robustness of PONS-transformed digital signals to noise and loss in a transmission channel.https://cassyni-user-files-prod.s3.amazonaws.com/LA4FP3UwaTssRJkSgysBSW https://cassyni.com/events/QJ4mo7oJpbCjLb1aJcVicV/seminar/qa https://cassyni.com/slides/outline/QJ4mo7oJpbCjLb1aJcVicV https://cassyni.com/events/QJ4mo7oJpbCjLb1aJcVicV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/uU37skSmWi3zA2Uyb6PFt https://cassyni.com/events/QJ4mo7oJpbCjLb1aJcVicV?videoPreview=1 In vivo lung morphometry with hyperpolarised xenon-129 lung MRInohttps://cassyni.com/events/QJ4mo7oJpbCjLb1aJcVicV?videoPreview=12023-08-15T04:00:00+00:002751.92The Auckland Bioengineering InstituteThe use of hyperpolarised noble gases, such as xenon-129 ($^{129}$Xe), as inhaled MRI contrast agents can provide novel information about the function and microstructure of the lungs. Hyperpolarised $^{129}$Xe lung MRI has great potential as a non-ionising radiation clinical tool for early detection and understanding lung disease pathophysiology. I recently returned to the Auckland Bioengineering Institute after 8 years at the University of Sheffield where I developed new techniques for measuring lung microstructure or morphometry *in vivo* with $^{129}$Xe diffusion-weighted MRI. $^{129}$Xe lung morphometry is now being used in a diagnostic clinical setting for patients with a range of pulmonary diseases. In this talk I will cover some basics of hyperpolarised $^{129}$Xe lung MRI, the acquisition and analysis techniques used for $^{129}$Xe lung morphometry, highlight some novel clinical studies using this technique, and discuss the potential opportunities for lung MRI in New Zealand. https://cassyni-user-files-prod.s3.amazonaws.com/uU37skSmWi3zA2Uyb6PFt https://cassyni.com/slides/outline/KMajLHL4S1fhwVJEJ8nitM https://cassyni.com/events/KMajLHL4S1fhwVJEJ8nitM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DNHJZnuuZDuUu2k2EBpR7C https://cassyni.com/events/KMajLHL4S1fhwVJEJ8nitM?videoPreview=1 Impact response of granular materials: From the origin of the universe to catastrophic asteroid strikesnohttps://cassyni.com/events/KMajLHL4S1fhwVJEJ8nitM?videoPreview=12023-03-22T12:00:00+00:004290.28Granular MatterGranular materials are large conglomerations of discrete macroscopic particles. Examples include seeds, sand, coals, powder of pharmacy, etc. Though simple, they show unique properties different from other familiar forms of matter. The unusual behaviors of granular materials are clearly illustrated in various impact processes, where the impact-induced fast deformation of granular materials leads to emergent flow patterns revealing distinctive granular physics. Here, we explored the impact response of granular materials in two specific experiments: First, we investigated impact cratering in granular media induced by the strike of liquid drops—a ubiquitous phenomenon relevant to many important environmental, agricultural and industrial processes. Surprisingly, we found that granular impact cratering by liquid drops follows the same energy scaling and reproduces the same crater morphology as that of asteroid impact craters. Inspired by this similarity, we develop a simple model that quantitatively describes various features of liquid-drop imprints in granular media. Our study sheds light on the mechanisms governing raindrop impacts on granular surfaces and reveals an interesting analogy between familiar phenomena of raining and catastrophic asteroid strikes. Second, we performed the granular analog to “water bell” experiments. When a wide jet of granular material impacts on a fixed cylindrical target, it deforms into a sharply-defined sheet or cone with a shape mimicking a liquid of zero surface tension. The jets' particulate nature appears when the number of particles in the beam cross-section is decreased: the emerging structures broaden, gradually disintegrating into diffuse sprays. The experiment reveals a universal fluid structure arising from the collision of discrete particles, which has a counterpart in the behavior of quark-gluon plasmas created by colliding heavy ions at the Relativistic Heavy Ion Colliders.https://cassyni-user-files-prod.s3.amazonaws.com/DNHJZnuuZDuUu2k2EBpR7C https://cassyni.com/slides/outline/5XRp39DN9CAEJJqXPTSK9X https://cassyni.com/events/5XRp39DN9CAEJJqXPTSK9X/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AHrw47HpEdhAwPQxB3hR74 https://cassyni.com/events/5XRp39DN9CAEJJqXPTSK9X?videoPreview=1 Hyper-Realistic and Immersive Imaging for Enhanced Quality of Experiencenohttps://cassyni.com/events/5XRp39DN9CAEJJqXPTSK9X?videoPreview=12022-04-07T12:30:00+00:002683.04Journal on Image and Video ProcessingProducing truly realistic and immersive digital imaging is widely seen as the ultimate goal towards further improving Quality of Experience (QoE) for end users of multimedia services. The human visual system is able to perceive a wide range of colors, luminous intensities, and depth, as present in a real scene. However, current traditional imaging technologies cannot capture nor reproduce such a rich visual information. Recent research innovations have made it possible to address these bottlenecks in multimedia systems. As a result, new multimedia signal processing areas have emerged such as ultra-high definition, high frame rate, high dynamic range imaging, light fields, and point cloud. These technologies have the potential to bring a leap forward for upcoming multimedia systems. However, the effective deployment of hyper-realistic video technologies entails many technical and scientific challenges. In this talk, I will discuss recent research activities covering several aspects of hyper-realistic imaging, including point cloud compression, light field compression, and semantic-aware tone mapping for high dynamic range imaging.https://cassyni-user-files-prod.s3.amazonaws.com/AHrw47HpEdhAwPQxB3hR74 https://cassyni.com/events/24taiMgh4zHbGcXxjo4Mch/abstract https://cassyni-user-files-prod.s3.amazonaws.com/66ovDwVg9KNJKPHuiEhtyL https://cassyni.com/events/Cw9sjPvEj4U4ntMzMLJ3ZX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JRsS1zLR9EGPCvQRoJqviJ https://cassyni.com/events/8z3uhpHhRUpTrR6J8jfA6h/seminar/qa https://cassyni.com/slides/outline/8z3uhpHhRUpTrR6J8jfA6h https://cassyni.com/events/8z3uhpHhRUpTrR6J8jfA6h/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Aadg1H9zg7Z1KCEJSpb2kW https://cassyni.com/events/8z3uhpHhRUpTrR6J8jfA6h?videoPreview=1 From “My Child” to “Our Children” – Fostering Positive Family Advocacy as a Path to Educational Equitynohttps://cassyni.com/events/8z3uhpHhRUpTrR6J8jfA6h?videoPreview=12024-04-25T16:00:00+00:003139.12Lived Places PublishingA conversation between **Liz Dempsey Lee**, author of *Parents as Advocates: Supporting K-12 Students and their Families Across Identities* and **Janise Hurtig**, Lived Places Publishing Collection Editor. Family advocacy – the practice of families advocating for their school-aged children – is constantly evolving; indeed, family advocacy in schools is a reflection of this moment in time and of the various dynamics at work in society. In some ways, the dynamics of family advocacy have led to better education and stronger family-school relationships; in other ways, they have become louder and more contentious. More generally, family advocacy continues to be uneven across social identities, with some families being heard frequently and clearly, while others are not heard at all. At times, families and educators alike approach family advocacy with trepidation. However, family advocacy does not have to be a scary prospect. Both parents and educators can walk into advocacy with a set of tools and strategies to navigate the moment, to pull forward the voices of families less heard and to harness the function of K12 education as a town forum. In this conversation, we will discuss how recognizing and addressing family advocacy is critical to creating educational equity. We’ll also explore how conflict is a normal and expected byproduct of the family-school relationship and how demystifying and educating families around effective advocacy can build relationships and move educational communities from a focus on “my child” to a focus on “our children.” https://cassyni-user-files-prod.s3.amazonaws.com/Aadg1H9zg7Z1KCEJSpb2kW https://cassyni.com/slides/outline/Bwrfe2dBr9Mv88XzFMpikd https://cassyni.com/events/Bwrfe2dBr9Mv88XzFMpikd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RqUY3qeEJaBKCg8fPqe4Cn https://cassyni.com/events/Bwrfe2dBr9Mv88XzFMpikd?videoPreview=1 Understanding local plant extinctions before it is too late: bridging evolutionary genomics with global ecologynohttps://cassyni.com/events/Bwrfe2dBr9Mv88XzFMpikd?videoPreview=12023-10-23T16:30:00+00:002032.08New PhytologistUnderstanding evolutionary genomic and population processes within a species range is key to anticipating the extinction of plant species before it is too late. However, most models of biodiversity risk under global change do not account for the genetic variation and local adaptation of different populations. Population diversity is critical to understanding extinction because different populations may be more or less susceptible to global change and, if lost, would reduce the total diversity within a species. Two new modeling frameworks advance our understanding of extinction from a population and evolutionary angle: Rapid climate change-driven disruptions in population adaptation are predicted from associations between genomes and local climates. Furthermore, losses of population diversity from global land-use transformations are estimated by scaling relationships of species' genomic diversity with habitat area. Overall, these global eco-evolutionary methods advance the predictability – and possibly the preventability – of the ongoing extinction of plant species.https://cassyni-user-files-prod.s3.amazonaws.com/RqUY3qeEJaBKCg8fPqe4Cn https://cassyni.com/slides/outline/HP1wGBFr5YP3Q1pBYZ14Ld https://cassyni.com/events/HP1wGBFr5YP3Q1pBYZ14Ld/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DdnGdDpVz45Zfic6KLWu82 https://cassyni.com/events/HP1wGBFr5YP3Q1pBYZ14Ld?videoPreview=1 Introducing Transformative Plant Biotechnology: Using microalgae to produce high value compoundsnohttps://cassyni.com/events/HP1wGBFr5YP3Q1pBYZ14Ld?videoPreview=12023-09-20T15:30:00+00:002143.0The New Phytologist FoundationThere is enormous potential to use microalgae as feedstocks for everything from biofuels to recombinant proteins and high value chemicals, but to implement this technology in a sustainable and economic manner, it will be necessary to optimize many parameters. We have taken a synthetic biology approach to develop two microalgal strains as production platforms for plant diterpenoids. We have established ways to regulate transgene expression, which will be essential for sophisticated metabolic engineering. To demonstrate the potential for commercial exploitation of these platforms we have grown the engineered strains outdoors under natural conditions in the Algal Innovation Centre in Cambridge, which has allowed us to identify bottlenecks and challenges that will need to be overcome to make such systems economically and sustainably viable. **Co-Authors**: Payam Mehrshahi, Katrin Geisler, Nhan-An Tranhttps://cassyni-user-files-prod.s3.amazonaws.com/DdnGdDpVz45Zfic6KLWu82 https://cassyni.com/slides/outline/VjE3RGRy3zDuHh3zWuZnUm https://cassyni.com/events/VjE3RGRy3zDuHh3zWuZnUm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FrhVLJEMxca3sPCKXMizrS https://cassyni.com/events/VjE3RGRy3zDuHh3zWuZnUm?videoPreview=1 Introducing Transformative Plant Biotechnology: Multi-Knock – a multi-targeted transportome-scale amiRNA and CRISPR toolbox to overcome functional redundancy in plantsnohttps://cassyni.com/events/VjE3RGRy3zDuHh3zWuZnUm?videoPreview=12023-09-22T11:15:00+00:001016.56The New Phytologist FoundationPlant genomes are characterized by large and complex gene families that often result in similar and partially overlapping functions. This genetic redundancy severely hampers current efforts to uncover novel phenotypes, delaying basic genetic research and breeding programs. To address the problem of masked phenotypic variation due to functional redundancy, we developed and validated Multi-Knock, a novel genetic approach in plants that combines forward-genetics with dynamically targeted genome-scale CRISPR/Cas9 tools. A total of 59,129 multi-targeted sgRNAs, divided into 10 functional sub-libraries targeting 16,152 genes in Arabidopsis, were designed, synthesized, and cloned into a genome-editing intronized Cas9 vector. From this collection, 5,635 sgRNAs targeting 1,123 of the 1,327 transporters (TRP) in Arabidopsis were cloned into four different Cas9 vectors generating independent CRISPR libraries, wherein each sgRNA was designed to target closely related homologues within sub-clades in transporter families. A proof of concept forward-genetic screen using over 3,500 CRISPR lines targeting the plant transportome recovered multiple known phenotypes in Arabidopsis, demonstrating the validity of the approach. Moreover, our screen allowed us to uncover novel transporters whose function has been hidden due to genetic redundancy. Furthermore, we have established another unique targeted transportome-scale, forward-genetic approach to overcome functional redundancy in Arabidopsis. We generated a new tissue-specific amiRNA toolbox, containing libraries designed to target multiple transporter genes, driven under cell type-specific promoters. With the ability to overcome functional redundancy in a transportome-scale, cell type-specific manner, this toolbox will allow the plant research community to study previously hidden genetic factors required for long- and short-distance translocation of signaling molecules.https://cassyni-user-files-prod.s3.amazonaws.com/FrhVLJEMxca3sPCKXMizrS https://cassyni.com/slides/outline/TFz2BrCLrhTNFXpD47mRUZ https://cassyni.com/events/TFz2BrCLrhTNFXpD47mRUZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NwhypimioAATJbwFcXFrrr https://cassyni.com/events/TFz2BrCLrhTNFXpD47mRUZ?videoPreview=1 Dawn of 'life-like' molecular roboticsnohttps://cassyni.com/events/TFz2BrCLrhTNFXpD47mRUZ?videoPreview=12021-05-12T12:00:00+00:002257.28Discover Applied SciencesAdvancements in nanotechnology, bioengineering, and chemistry enabled methods and tools to create robots from the molecular scale. Molecular robotics is a new interdisciplinary field focusing on the development of robots based on the synthesis and self-assembly of molecules. Especially, molecular robots using DNA have been rapidly advanced during the past ten years, leading to a “Cambrian explosion” of various types of biomolecular robots. This seminar overviews the field by illustrating some latest examples, including our mesoscale DNA-based machines powered by artificial metabolism. Metabolism is one of the most significant characteristics of life. By mimicking this mechanism, our system achieved a dynamic generation and regeneration of mesoscale DNA materials. Two types of machines, locomotion and racing, were programmed by using this system. Applications of the system and a potential route towards the realisation of further life-like characteristics will also be discussed.https://cassyni-user-files-prod.s3.amazonaws.com/NwhypimioAATJbwFcXFrrr https://cassyni.com/events/9yHsZvYyVg5Faf3wVn34Cu/seminar/qa https://cassyni.com/slides/outline/9yHsZvYyVg5Faf3wVn34Cu https://cassyni.com/events/9yHsZvYyVg5Faf3wVn34Cu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/ADGeP9KkjfPZu9jfSbNWEJ https://cassyni.com/events/9yHsZvYyVg5Faf3wVn34Cu?videoPreview=1 Vision 2050: Reaction Engineering Roadmapnohttps://cassyni.com/events/9yHsZvYyVg5Faf3wVn34Cu?videoPreview=12023-12-04T13:00:00+00:003594.24ElsevierA dozen chemical reaction engineers from academia and industry recently published a sequel to the “Vision 2020: Reaction Engineering Roadmap,” published in 2001. In this webinar, that team of authors will provide a summary of our recently issued perspective paper, “Vision 2050: Reaction Engineering Roadmap,” available from ACS Engineering Au. This webinar will follow the format of our recent paper, with brief summaries of our perspectives regarding the field of reaction engineering in the context of four industry sectors (basic chemicals, specialty chemicals, pharmaceuticals, and polymers) and five technology areas (reactor system selection, design and scale-up, chemical mechanism development and property estimation, catalysis, nonstandard reactor types, and electrochemical systems). This seminar will feature multiple speakers, a subset of the team of the corresponding paper's authors. The entire coauthor team is as follows: Praveen Bollini (U. of Houston), Moiz Diwan (Abbvie), Pankaj Gautam (SABIC), Ryan Hartman (New York U.), Dan Hickman (Dow), Marty Johnson (Eli Lilly), Moto Kawase (Kyoto U.), Matt Neurock (U. of Minnesota), Gregory Patience (Polytechnique Montréal), Alan Stottlemyer (Dow), Dion Vlachos (U. of Delaware), and Ben Wilhite (Texas A&M).https://cassyni-user-files-prod.s3.amazonaws.com/ADGeP9KkjfPZu9jfSbNWEJ https://cassyni.com/slides/outline/CSXtoLnbgxqjwbXW3Twgvq https://cassyni.com/events/CSXtoLnbgxqjwbXW3Twgvq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JPEyggYm319AATnr4qVy8i https://cassyni.com/events/CSXtoLnbgxqjwbXW3Twgvq?videoPreview=1 Wetting and swelling of soft fibresnohttps://cassyni.com/events/CSXtoLnbgxqjwbXW3Twgvq?videoPreview=12022-05-11T14:00:00+00:003128.24Leeds Institute for Fluid DynamicsTextiles are commonly used to absorb liquid or filtrate droplets from an aerosol stream. The liquid distribution on the fibres plays a key role in many phenomena associated with liquid/textiles interactions, which I will illustrate with several model experiments, in particular to answer the seemingly simple question: how fast does a drop get absorbed by a textile? We will look at the absorption dynamics of isolated drops on a single swelling fibre as well as in between two flexible fibres, as a minimal model of yarns, and highlight the role played by the tension within the fibres. In particular, I will show that fluid is spontaneously released out of the fibre during the absorption, due to a combination of the global compression induced by swelling with the local saturation of liquid at the drop position. This local expulsion of fluid creates a new droplet at the surface of the fibre, which then interacts with the drops initially present, inducing motions or even coalesce!https://cassyni-user-files-prod.s3.amazonaws.com/JPEyggYm319AATnr4qVy8i https://cassyni.com/slides/outline/LqanhbJQZ7BTFQaNPtDBnM https://cassyni.com/events/LqanhbJQZ7BTFQaNPtDBnM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RWaAQ1JHbSd8Mf4y1vmL2A https://cassyni.com/events/LqanhbJQZ7BTFQaNPtDBnM?videoPreview=1 Fingering Convection in MHD: problems with parasites, and speculative solutionsnohttps://cassyni.com/events/LqanhbJQZ7BTFQaNPtDBnM?videoPreview=12021-11-25T12:00:00+00:002749.08Leeds Institute for Fluid DynamicsObservations of a variety of stars across the HR diagram point towards mixing (e.g. of metals, heat, or angular momentum) in radiation zones beyond what can be accounted for by molecular diffusion alone, or so-called "missing mixing problems". This motivates studies of instabilities and turbulence that can exist in these stratified plasmas and possibly provide the missing mixing. Here I describe simulations of thermohaline mixing, also known as fingering convection, a potential candidate for solving multiple missing mixing problems. Recent simulations showed fingering convection yields significant levels of mixing when magnetic fields are included, possibly solving some mixing problems in RGB stars, and found these trends with magnetic field could be explained by a simple "parasitic saturation" model. I will present simulations in more realistic parameter regimes that question the validity of these models, which break down in these regimes despite working remarkably well in previous MHD and hydrodynamic studies. This may have implications for other systems where parasitic saturation models are used, such as the MRI in accretion disks.https://cassyni-user-files-prod.s3.amazonaws.com/RWaAQ1JHbSd8Mf4y1vmL2A https://cassyni.com/events/KrHacE1MgC5JaekNHujryT/seminar/qa https://cassyni.com/slides/outline/KrHacE1MgC5JaekNHujryT https://cassyni.com/events/KrHacE1MgC5JaekNHujryT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VDjzvoGqo2VZEu1RZrc7Av https://cassyni.com/events/RHRE7k88WEAhi4LAJXykvq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AeD9QFAUyEGmwVSvL6TazJ https://cassyni.com/slides/outline/628fK5tfPNZpwUHfPEPTEd https://cassyni.com/events/628fK5tfPNZpwUHfPEPTEd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7GYVZwxmtLv7XqXV2Vww6N https://cassyni.com/events/628fK5tfPNZpwUHfPEPTEd?videoPreview=1 Immune cell gene expression signatures in diffuse glioma are associated with IDH mutation status, patient outcome and malignant cell state, and highlight the importance of specific cell subsets in glioma biologynohttps://cassyni.com/events/628fK5tfPNZpwUHfPEPTEd?videoPreview=12023-09-21T14:00:00+00:002910.92Center for Cancer TrainingThis presentation will discuss the biological and clinical significance of the immune cell environment related to IDH mutation status, patient prognosis and the mesenchymal state in diffuse gliomas. The tumor micro-environment (TME) plays critical role in various cancers, including gliomas. We estimated immune cell type-specific gene expression profiles in glioma datasets and found estimated proportions and gene expression profiles that varied according to IDH mutation status. Cluster-of-cluster analyses of immune cell gene expression identified groups with distinct survival outcomes in IDH-WT and IDH-MUT tumors. We verified these findings by applying a signature matrix derived from single-cell RNA Seq data. To link immune cell signatures with outcomes in checkpoint therapy, we found a significant association of monocytic gene expression clusters with patient survival and with mesenchymal scores. Integrating immune cell-based gene expressions with previously described malignant cell states in glioma demonstrated that macrophage M0 abundance significantly correlated with mesenchymal state in IDH-WT gliomas. Overall, these results highlight biological and clinical significance of immune cell environment related to IDH mutation status, patient prognosis and the mesenchymal state in diffuse gliomas.https://cassyni-user-files-prod.s3.amazonaws.com/7GYVZwxmtLv7XqXV2Vww6N https://cassyni.com/slides/outline/3Yte5ff3C5oHuK3svSb6ER https://cassyni.com/events/3Yte5ff3C5oHuK3svSb6ER/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AjXYdhswBtiC5QneQZh5HG https://cassyni.com/events/3Yte5ff3C5oHuK3svSb6ER?videoPreview=1 MultiHypExp: A Mathematica package for expanding multivariate hypergeometric functions in terms of multiple polylogarithmsnohttps://cassyni.com/events/3Yte5ff3C5oHuK3svSb6ER?videoPreview=12024-03-11T12:30:00+00:001770.48Computer Physics CommunicationsWe present the Mathematica package MultiHypExp that allows for the expansion of multivariate hypergeometric functions (MHFs), especially those likely to appear as solutions of multi-loop, multi-scale Feynman integrals, in the dimensional regularization parameter. The series expansion of MHFs can be carried out around integer values of parameters to express the series coefficients in terms of multiple polylogarithms. The package uses a modified version of the algorithm prescribed in [1]. In the present work, we relate a given MHF to a Taylor series expandable MHF by a differential operator. The Taylor expansion of the latter MHF is found by first finding the associated partial differential equations (PDEs) from its series representation. We then bring the PDEs to the Pfaffian system and further to the canonical form, and solve them order by order in the expansion parameter using appropriate boundary conditions. The Taylor expansion so obtained and the differential operators are used to find the series expansion of the given MHF. We provide examples to demonstrate the algorithm and to describe the usage of the package, which can be found [here](https://github.com/souvik5151/MultiHypExp)https://cassyni-user-files-prod.s3.amazonaws.com/AjXYdhswBtiC5QneQZh5HG https://cassyni.com/events/VF7GYYaHGPGZiFeSZDibRX/seminar/qa https://cassyni.com/slides/outline/VF7GYYaHGPGZiFeSZDibRX https://cassyni.com/events/VF7GYYaHGPGZiFeSZDibRX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/R3fH4AaBktRhnYBCc5vWQn https://cassyni.com/events/VF7GYYaHGPGZiFeSZDibRX?videoPreview=1 Why the hexagon of opposition is really a triangle: logical structures as geometric shapesnohttps://cassyni.com/events/VF7GYYaHGPGZiFeSZDibRX?videoPreview=12024-04-24T14:00:00+00:003974.04Logica UniversalisThis paper suggests a new approach (with old roots) to the study of the connection between logic and geometry. Traditionally, most logic diagrams associate only vertices of shapes with propositions. The new approach, which can be dubbed ’full logical geometry’, aims to associate every element of a shape (edges, faces, etc.) with a proposition. The roots of this approach can be found in the works of Carroll, Jacoby, and more recently, Dubois and Prade. However, its potential has not been duly appreciated, probably because of the complexity of the diagrams in these works. The following study demonstrates how the Hexagon of Opposition can be represented as a triangle and Classical Logic as a tetrahedron (rather than a rhombic dodecahedron). It then applies the approach to modal logic, extending the tetrahedron for the logic KT into a dipyramid and a cube for KD, and finally an octahedron for K. Some possible directions for further research are also indicated.https://cassyni-user-files-prod.s3.amazonaws.com/R3fH4AaBktRhnYBCc5vWQn https://cassyni.com/events/Fu6kEkqAAXe9nzHgto9pNZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/ATbSuV9WxPfcjePDhMxmW6 https://cassyni.com/events/53LfH3sZkx8fYZtbdSRJ1B/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4aesrDXG8bZ4Rqu7k6kmY2 https://cassyni.com/events/7WagWU7BxEu9uWNAB8Kvj7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FWGtaobA7xtjUp9di7Qpnz https://cassyni.com/slides/outline/HsinY7w9Kine3BGKYKxCRj https://cassyni.com/events/HsinY7w9Kine3BGKYKxCRj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Vd9ZJmNRtWE82kzFjAoJhk https://cassyni.com/events/HsinY7w9Kine3BGKYKxCRj?videoPreview=1 Base-Metal Catalysisnohttps://cassyni.com/events/HsinY7w9Kine3BGKYKxCRj?videoPreview=12023-09-22T16:00:00+00:009024.0Thieme GroupCatalysis with earth-abundant metals, often referred to as base metals, is having a transformative impact on synthetic chemistry. The research in this area is driven not only by the common interest in the sustainability of chemical synthesis but also by the vast opportunity to discover and develop novel reaction chemistry that is not attainable with rare and precious metal catalysts.https://cassyni-user-files-prod.s3.amazonaws.com/Vd9ZJmNRtWE82kzFjAoJhk https://cassyni.com/events/Ujz5ZAAgyny7ZT6M9sBtNZ/seminar/qa https://cassyni.com/slides/outline/Ujz5ZAAgyny7ZT6M9sBtNZ https://cassyni.com/events/Ujz5ZAAgyny7ZT6M9sBtNZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/P35kGaDE6Yshfjh3mSDKjc https://cassyni.com/events/Ujz5ZAAgyny7ZT6M9sBtNZ?videoPreview=1 Disentangling contributions to past and future trends in US surface soil moisturenohttps://cassyni.com/events/Ujz5ZAAgyny7ZT6M9sBtNZ?videoPreview=12024-03-11T15:00:00+00:002013.68Nature WaterIn this presentation, I will outline a simple, idealized model of the land surface that was used in a recent paper to understand observed decadal soil moisture trends from satellites and ground probe observations. The different processes contributing to long-term trends will be discussed, as will the implications of the results for understanding how long-term climate change will influence the land surface.https://cassyni-user-files-prod.s3.amazonaws.com/P35kGaDE6Yshfjh3mSDKjc https://cassyni.com/slides/outline/XDE6naQKB5jbvPZuhZ6X6V https://cassyni.com/events/XDE6naQKB5jbvPZuhZ6X6V/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Kx6BeSiFGyWs1z4PoTJZC https://cassyni.com/events/XDE6naQKB5jbvPZuhZ6X6V?videoPreview=1 Clinical assessment of wellbeing and medication adherence after kidney transplantationnohttps://cassyni.com/events/XDE6naQKB5jbvPZuhZ6X6V?videoPreview=12024-02-08T15:00:00+00:002560.04Imperial College Renal and Transplant CentreNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/Kx6BeSiFGyWs1z4PoTJZC https://cassyni.com/slides/outline/aKr1ZapqcWdMqZqAroRgh https://cassyni.com/events/aKr1ZapqcWdMqZqAroRgh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WmubMedgNsBpVXLR6BNC3Q https://cassyni.com/events/aKr1ZapqcWdMqZqAroRgh?videoPreview=1 Augmenting reality with The World Avatar - automating data centric engineeringnohttps://cassyni.com/events/aKr1ZapqcWdMqZqAroRgh?videoPreview=12023-10-11T15:00:00+00:003318.92Data-Centric Engineering JournalThe advent of digitalization brings forth new opportunities for data-centric engineering, leading to increased efficiency in the realms of science, engineering, and society. However, the implications of digitalization for environmental and social sustainability remain uncertain. We suggest that knowledge graph technology plays a pivotal role in addressing this challenge. In this presentation, I will introduce "The World Avatar," a dynamic knowledge graph (dKG) designed to construct a comprehensive digital replica of the world at large. I will elucidate the core concepts and principles underpinning this initiative, showcasing how it can facilitate seamless integration among various data formats and software systems, ultimately enabling automated data-centric engineering. Additionally, I will present a variety of use cases that demonstrate how The World Avatar can support cross-domain applications spanning diverse scales, from the molecular level to the global stage. These applications aim to enhance efficiency, reduce costs, diminish carbon emissions, and bolster resilience.https://cassyni-user-files-prod.s3.amazonaws.com/WmubMedgNsBpVXLR6BNC3Q https://cassyni.com/events/443TBgaWt32Wsp4bXTwyCH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QZEW6mkT2wNw8TUCvNBbGr https://cassyni.com/slides/outline/DvXxAekwp4MVFWoe9DN9pq https://cassyni.com/events/DvXxAekwp4MVFWoe9DN9pq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GbcY4FhQBYd83LwtNCsGPg https://cassyni.com/slides/outline/GPmyQ4za1M7ycTHCguGnYm https://cassyni.com/events/GPmyQ4za1M7ycTHCguGnYm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QyHk4cnGDjgfqv7r77V19G https://cassyni.com/events/GPmyQ4za1M7ycTHCguGnYm?videoPreview=1 Approximating functions, functionals, and operators using deep neural networks for diverse applicationsnohttps://cassyni.com/events/GPmyQ4za1M7ycTHCguGnYm?videoPreview=12021-04-07T10:00:00+00:004291.72Data-Centric Engineering JournalWe will present a new approach to develop a data-driven, learning-based framework for predicting outcomes of physical systems and for discovering hidden physics from noisy data. We will introduce a deep learning approach based on neural networks (NNs) and generative adversarial networks (GANs). Unlike other approaches that rely on big data, here we “learn” from small data by exploiting the information provided by the physical conservation laws, which are used to obtain informative priors or regularize the neural networks. We will demonstrate the power of PINNs for several inverse problems, and we will demonstrate how we can use multi-fidelity modeling in monitoring ocean acidification levels in the Massachusetts Bay. We will also introduce new NNs that learn functionals and nonlinear operators from functions and corresponding responses for system identification. The universal approximation theorem of operators is suggestive of the potential of NNs in learning from scattered data any continuous operator or complex system. We first generalize the theorem to deep neural networks, and subsequently we apply it to design a new composite NN with small generalization error, the deep operator network (DeepONet), consisting of a NN for encoding the discrete input function space (branch net) and another NN for encoding the domain of the output functions (trunk net). We demonstrate that DeepONet can learn various explicit operators, e.g., integrals, Laplace transforms and fractional Laplacians, as well as implicit operators that represent deterministic and stochastic differential equations. More generally, DeepOnet can learn multiscale operators spanning across many scales and trained by diverse sources of data simultaneously. https://cassyni-user-files-prod.s3.amazonaws.com/QyHk4cnGDjgfqv7r77V19G https://cassyni.com/slides/outline/Rna3Dm3cCBPvgZLsuZLdth https://cassyni.com/events/Rna3Dm3cCBPvgZLsuZLdth/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6K7KoE53rspgJWU2zTFbWN https://cassyni.com/events/Rna3Dm3cCBPvgZLsuZLdth?videoPreview=1 Automated optimisation of the solubility of a hyper-stable α-amylasenohttps://cassyni.com/events/Rna3Dm3cCBPvgZLsuZLdth?videoPreview=12024-06-03T10:00:00+00:00981.8Royal Society PublishingMost successes of computational protein engineering to date have focused on enhancing one biophysical trait, while multi-trait optimisation remains a challenge. Different biophysical properties are often conflicting, as mutations that improve one tend to worsen the others. In this study, we explored the potential of an automated computational design strategy, called CamSol Combination, to optimise solubility and stability of enzymes without affecting their activity. Specifically, we focus on B. licheniformis α-amylase (BLA), a hyper-stable enzyme that finds diverse application in industry and biotechnology. We validate the computational predictions by producing 10 BLA variants, including the WT and 3 designed models harbouring between 6 and 8 mutations each. Our results show that all 3 models have substantially improved relative solubility over the WT, unaffected catalytic rate, and retained hyper-stability, supporting the algorithm's capacity to optimise enzymes. High stability and solubility embody enzymes with superior resilience to chemical and physical stresses, enhance manufacturability, and allow for high concentration formulations characterised by extended shelf-lives. This ability to readily optimise solubility and stability of enzymes will enable the rapid and reliable generation of highly robust and versatile reagents, poised to contribute to advancements in diverse scientific and industrial domains. https://cassyni-user-files-prod.s3.amazonaws.com/6K7KoE53rspgJWU2zTFbWN https://cassyni.com/events/GtvnW5v3hJMUeGsFnXz3CH/seminar/qa https://cassyni.com/slides/outline/GtvnW5v3hJMUeGsFnXz3CH https://cassyni.com/events/GtvnW5v3hJMUeGsFnXz3CH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DpAETXwftbGre4jSHAKWqC https://cassyni.com/events/GtvnW5v3hJMUeGsFnXz3CH?videoPreview=1 Unraveling Tissue Mechanics: Investigating Structure, Fluid Dynamics, and Rheological Behaviornohttps://cassyni.com/events/GtvnW5v3hJMUeGsFnXz3CH?videoPreview=12024-06-27T14:00:00+00:005158.32Journal of Biological PhysicsFrom the beginnings of life as a single cell to the intricate assembly of a fully developed organism, embryonic tissues undergo significant transformations to develop vital organs, while adult organisms continuously adapt to mechanical forces at cellular and tissue levels, crucial for sustaining essential life functions. This presentation delves into the intricate relationship between cellular resistance to mechanical forces and their coordinated movements, fundamental to both embryonic growth and adult health. I will explore three key aspects: Using computational models based on soft matter physics, we analyze shear-induced rigidity and the mechanisms driving fluidity in epithelial tissues; we examine the complex interactions between external mechanical stresses and internal cellular dynamics, uncovering a range of rheological behaviors like shear thickening—essential for understanding responses under diverse conditions; and we investigate the effects of cellular processes such as division and apoptosis on tissue states, focusing on the emergence of hexatic phases—an intermediate state displaying properties of both solids and liquids.https://cassyni-user-files-prod.s3.amazonaws.com/DpAETXwftbGre4jSHAKWqC https://cassyni.com/slides/outline/ERf9A3AY6eewQKMjYZtrso https://cassyni.com/events/ERf9A3AY6eewQKMjYZtrso/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UySjjtbWaVhPxzduxNGHwU https://cassyni.com/events/ERf9A3AY6eewQKMjYZtrso?videoPreview=1 Physics-Informed Dynamic Mode Decomposition (PI-DMD)nohttps://cassyni.com/events/ERf9A3AY6eewQKMjYZtrso?videoPreview=12022-08-26T14:00:00+00:001421.52Brunton LabIn this work, we demonstrate how physical principles -- such as symmetries, invariances, and conservation laws -- can be integrated into the dynamic mode decomposition (DMD). DMD is a widely-used data analysis technique that extracts low-rank modal structures and dynamics from high-dimensional measurements. However, DMD frequently produces models that are sensitive to noise, fail to generalize outside the training data, and violate basic physical laws. Our physics-informed DMD (piDMD) optimization, which may be formulated as a Procrustes problem, restricts the family of admissible models to a matrix manifold that respects the physical structure of the system. We focus on five fundamental physical principles -- conservation, self-adjointness, localization, causality, and shift-invariance -- and derive several closed-form solutions and efficient algorithms for the corresponding piDMD optimizations. With fewer degrees of freedom, piDMD models are less prone to overfitting, require less training data, and are often less computationally expensive to build than standard DMD models. We demonstrate piDMD on a range of challenging problems in the physical sciences, including energy-preserving fluid flow, travelling-wave systems, the Schrödinger equation, solute advection-diffusion, a system with causal dynamics, and three-dimensional transitional channel flow. In each case, piDMD significantly outperforms standard DMD in metrics such as spectral identification, state prediction, and estimation of optimal forcings and responses.https://cassyni-user-files-prod.s3.amazonaws.com/UySjjtbWaVhPxzduxNGHwU https://cassyni.com/slides/outline/EvJkCip4Y7CzQ5td91Bf97 https://cassyni.com/events/EvJkCip4Y7CzQ5td91Bf97/abstract https://cassyni-user-files-prod.s3.amazonaws.com/R6vRFg8oX1Gy4LHFogZZBk https://cassyni.com/events/EvJkCip4Y7CzQ5td91Bf97?videoPreview=1 Double Dipping: Problems and solutions, with applications to single-cell RNA-sequencing datanohttps://cassyni.com/events/EvJkCip4Y7CzQ5td91Bf97?videoPreview=12022-12-02T14:00:00+00:003396.24AI Institute in Dynamic SystemsIn contemporary applications, it is common to collect very large data sets with the vaguely-defined goal of hypothesis generation. Once a dataset is used to generate a hypothesis, we might wish to test that hypothesis on the same set of data. However, this type of 'double dipping' violates a cardinal rule of statistical hypothesis testing: namely, that we must decide what hypothesis to test before looking at the data. When this rule is violated, then standard statistical hypothesis tests (such as t-tests and z-tests) fail to control the selective Type 1 error --- that is, the probability of rejecting the null hypothesis, provided that the null hypothesis holds, and given that we decided to test this null hypothesis. While double dipping is pervasive throughout many application areas, in this talk I'll focus on the analysis of single-cell RNA-sequencing data. I'll introduce count splitting, an approach to overcome issues associated with double dipping in the context of latent variable estimation for count-valued data.https://cassyni-user-files-prod.s3.amazonaws.com/R6vRFg8oX1Gy4LHFogZZBk https://cassyni.com/slides/outline/9VB6hChHi57v1DePY6Bs9f https://cassyni.com/events/9VB6hChHi57v1DePY6Bs9f/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TpVF1SCBw2KYvzAbXExBTk https://cassyni.com/events/9VB6hChHi57v1DePY6Bs9f?videoPreview=1 Learning to control population of neuronsnohttps://cassyni.com/events/9VB6hChHi57v1DePY6Bs9f?videoPreview=12020-10-30T14:00:00+00:004318.04AI Institute in Dynamic SystemsSome brain disorders are hypothesized to have a dynamical origin; in particular, it has been hypothesized that some symptoms of Parkinson's disease are due to pathologically synchronized neural activity in the basal ganglia region of the brain. This talk will start by describing several theoretical/computational approaches for desynchronizing the activity of a group of neurons, including maximizing the Lyapunov exponent associated with their phase dynamics, optimal phase resetting, controlling the phase density, and the use of a supervised learning algorithm. However, while such approaches are effective in silico, they would be challenging to apply to real patients. This inspired us to consider both patient-collected and simulated local field potential readings from the basal ganglia to generate a model-free predictive algorithm with the goal of modulating beta band rhythms and predicting future brain activity in the basal ganglia subject to Parkinson’s disease. We construct artificial neural networks to first demonstrate the capacity to make meaningful predictions of bursting events in patient Parkinsonian data, then use the same framework to generate an adaptive control strategy applied to computational modeling. Our model shows meaningful success in predicting the future brain state in Parkinsonian patients compared to alternative approaches. With this baseline established, we demonstrate that the network can quickly learn precise control and maintain high fidelity to the control objective in a simulated environment, even if the underlying model's parameters vary.https://cassyni-user-files-prod.s3.amazonaws.com/TpVF1SCBw2KYvzAbXExBTk https://cassyni.com/slides/outline/MqQpxvPJ5stW3Nabo1h2vR https://cassyni.com/events/MqQpxvPJ5stW3Nabo1h2vR/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8pP13w733mjs46Evv1oF3c https://cassyni.com/events/MqQpxvPJ5stW3Nabo1h2vR?videoPreview=1 Recurrent hybridization mediated range expansion and climate change resilience in two keystone species of boreal forestsnohttps://cassyni.com/events/MqQpxvPJ5stW3Nabo1h2vR?videoPreview=12024-06-07T13:45:00+00:001042.12New Phytologist Foundation The ongoing global climate change poses a significant threat to biodiversity across various levels, potentially resulting in substantial biodiversity loss. Numerous studies have demonstrated the impact of specific genetic loci on allele distribution within a species' range, correlating with local environmental factors and reflecting instances of local adaptation. However, leveraging this data alone to predict species' adaptation to climate change remains a complex challenge. In this study, we utilized exome capture sequences alongside environmental niche reconstruction to evaluate diverse methodologies for gauging local adaptation and climate resilience in two widely distributed conifers: Norway spruce and Siberian spruce. These species, crucial to the boreal forest ecosystem, share an expansive hybrid zone. Our findings highlight the detectability of local adaptation in conifers through variations in allele frequencies, population-level ecological preferences, and historical niche shifts. Furthermore, through the integration of genetic and ecological data, we unveiled the pivotal role of hybridization in broadening the niche range of these conifers. This process may potentially enhance their ability to adapt to future climate changes. This combined genetic and ecological analysis also pinpointed genetically isolated populations at risk due to ongoing climate changes, emphasizing the urgent need for conservation efforts.https://cassyni-user-files-prod.s3.amazonaws.com/8pP13w733mjs46Evv1oF3c https://cassyni.com/events/XiNutbKns2xpttadJaTQ4M/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QQeLeAqZjhW6P9nRQNa4uL https://cassyni.com/events/Cwjx8cjrBdvKrcQaPRPzbP/seminar/qa https://cassyni.com/slides/outline/Cwjx8cjrBdvKrcQaPRPzbP https://cassyni.com/events/Cwjx8cjrBdvKrcQaPRPzbP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6nKLVCJDUMgpu6QPFG3YnJ https://cassyni.com/events/Cwjx8cjrBdvKrcQaPRPzbP?videoPreview=1 Of networks and regularization: new developments in Lagrangian Particle Trackingnohttps://cassyni.com/events/Cwjx8cjrBdvKrcQaPRPzbP?videoPreview=12025-02-11T15:00:00+00:003594.72Experiments in FluidsThis talk will introduce several recent developments in the the field of 3D particle tracking and related post-processing methods. The aspects that will be touched are: (i) Machine-learning based dectection of particle images and the implications for 3D position reconstruction. (ii) First experiences with high-performance-computing evaluations using the Shake-The-Box algorithm. (iii) Comparisons of several classes of flowfield-reconstruction approaches (Binning, Data Assimilation, Physics-Informed Neural Networks). https://cassyni-user-files-prod.s3.amazonaws.com/6nKLVCJDUMgpu6QPFG3YnJ https://cassyni.com/slides/outline/SHFGP5D22zskW2LPhfTc4u https://cassyni.com/events/SHFGP5D22zskW2LPhfTc4u/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Jyt17ovf7UK9XiCLiFxY9U https://cassyni.com/events/SHFGP5D22zskW2LPhfTc4u?videoPreview=1 Radiation Reveal: Moving from research engagement to involvementnohttps://cassyni.com/events/SHFGP5D22zskW2LPhfTc4u?videoPreview=12024-12-11T12:00:00+00:00653.36Research Seminars by Springer NatureHere, we report on the process of a highly impactful and successful creative, collaborative, and multi-partner public engagement project, Radiation Reveal. It brought together ten young adults aged 17–25-year-olds with experience of radiotherapy with researchers at Cancer Research UK RadNet City of London across three 2-hour online workshops. Our aims were to 1) initiate discussions between young adults and radiation researchers, and 2) identify what people wish they had known about radiotherapy before or during treatment. These aims were surpassed; other benefits included peer support, participants’ continued involvement in subsequent engagement projects, lasting friendships, creation of support groups for others, and creation and national dissemination of top ten tips for medical professionals and social media resources. A key learning was that this project required a dedicated and (com)passionate person with connections to national cancer charities. When designing the project, constant feedback is also needed from charities and young adults with and without radiotherapy experience. Finally, visually capturing discussions and keeping the door open beyond workshops further enhanced impact. Here, we hope to inform and inspire people to help project the patient voice in all we do.https://cassyni-user-files-prod.s3.amazonaws.com/Jyt17ovf7UK9XiCLiFxY9U https://cassyni.com/slides/outline/NL648EYhvhNKrqa7b7p16d https://cassyni.com/events/NL648EYhvhNKrqa7b7p16d/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AMPwSWvTCLYZtQaQGS49pr https://cassyni.com/events/NL648EYhvhNKrqa7b7p16d?videoPreview=1 Nitrogen plasma treated cotton fabrics coated with SiO2 followed by RGO deposition for water purification processnohttps://cassyni.com/events/NL648EYhvhNKrqa7b7p16d?videoPreview=12024-08-21T12:00:00+00:002183.24Chemical Physics ImpactExperimental investigations have been carried out to modify the surface properties of Cotton fabrics using low temperature DC glow discharge nitrogen plasma. Plasma treatment is an eco-friendly, dry and clean process over wet chemical methods and does not suffer from any environmental and health concerns [1]. The important plasma parameters such as power and working pressure are kept constant with various treatment times (5, 15, 30, and 60 mins). The plasma-treated cotton fabrics are optimized by XRD, FTIR, and SEM. A comparative study has been done for the untreated and different treated fibers. Pure SiO2 is coated on untreated and nitrogen plasma treated cotton fabrics by sputtering method. The samples are coated for different sputtering times (10 and 30 min). Finally, Reduced Graphene Oxide (RGO) is coated on plasma treated SiO2 deposited fabrics. RGO is prepared by modified hummers methods [2]. Our results provide a way to develop a filter for water purification.https://cassyni-user-files-prod.s3.amazonaws.com/AMPwSWvTCLYZtQaQGS49pr https://cassyni.com/events/NpjfAvCEN9vNrc71BZ6oMw/seminar/qa https://cassyni.com/slides/outline/NpjfAvCEN9vNrc71BZ6oMw https://cassyni.com/events/NpjfAvCEN9vNrc71BZ6oMw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6iAJU9rG44g6QTvcA5zmQr https://cassyni.com/events/NpjfAvCEN9vNrc71BZ6oMw?videoPreview=1 On generating image and video hallucinationsnohttps://cassyni.com/events/NpjfAvCEN9vNrc71BZ6oMw?videoPreview=12024-12-06T13:00:00+00:003518.04Journal on Image and Video Processing“Hallucination” is a term used in the AI community to describe the plausible falsehoods produced by deep generative neural networks. It is often considered a negative, especially in relation with large language models or medical image reconstruction. Yet, in many computational photography applications, we rely on such hallucinations to create pleasing images. It often does not matter if all (or any) information was present in the real world if the produced falsehoods are visually plausible. Starting from that premise, I will present our recent work on hallucinations in image reconstruction, image style creation, and texture synthesis, using different generative models such as GANs, diffusion networks, and neural cellular automata. With a nod to the dangers some of these hallucinations might pose, I will also briefly discuss our work on deep fake detection.https://cassyni-user-files-prod.s3.amazonaws.com/6iAJU9rG44g6QTvcA5zmQr https://cassyni.com/events/Vjp7pVFaWZgAMR6aYzfjWd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UGgF2Q7rJxEQVGSSCj5Pp2 https://cassyni.com/events/QoL5MenL7z98xKPEYWxjnV/seminar/qa https://cassyni.com/slides/outline/QoL5MenL7z98xKPEYWxjnV https://cassyni.com/events/QoL5MenL7z98xKPEYWxjnV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BwkaMgXjesgGKCDXLj98sG https://cassyni.com/events/QoL5MenL7z98xKPEYWxjnV?videoPreview=1 Smurfing the Square of Oppositionnohttps://cassyni.com/events/QoL5MenL7z98xKPEYWxjnV?videoPreview=12024-08-21T14:00:00+00:005850.04Logica UniversalisThis session is about the Special Issue of Logica Universalis (vol 18, nos 1-2, 2024) dedicated to the 7th World Congress on the Square of Opposition Leuven 2022. We discuss the history of the revival of the theory of opposition, with its emerging paradigms of research, and the related events that are organized in this perspective, including the latest one in Leuven in 2022. https://cassyni-user-files-prod.s3.amazonaws.com/BwkaMgXjesgGKCDXLj98sG https://cassyni.com/slides/outline/81HXnQnVCRJkYfpJAuH4pD https://cassyni.com/events/81HXnQnVCRJkYfpJAuH4pD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KyY2XACqoDeYDKzqmes3FC https://cassyni.com/events/81HXnQnVCRJkYfpJAuH4pD?videoPreview=1 Short- and long-read metagenomics of South African gut microbiomes reveal a transitional composition and novel taxanohttps://cassyni.com/events/81HXnQnVCRJkYfpJAuH4pD?videoPreview=12021-12-08T10:00:00+00:00724.04Microbiome Virtual International Forum While human gut microbiome research has largely focused on western populations, with a small minority of studies investigating nonwestern agriculturalist and hunter-gatherer societies, most of the world‚Äôs population resides between these two lifestyle extremes. We present the first study evaluating gut microbiome composition of two transitioning South African populations using short- and long-read sequencing. We analyzed shotgun sequencing samples from adult females living in rural Bushbuckridge (n=117) or urban Soweto (n=51) and find that these microbiomes are intermediate between those of western populations and previously studied agriculturalist and hunter-gatherer African populations. We found that widely used reference collections are incomplete for nonwestern microbiomes, resulting in a larger portion of unclassified sequencing in transitional and nonwestern populations and within-cohort beta diversity patterns that are reversed compared to reference-agnostic sequence comparison patterns. To improve reference databases, we performed de novo metagenomic assembly of long-read sequencing data to generate complete genomes of undescribed taxa, including Treponema and Lentisphaerae species. Collectively, our results suggest that South Africa‚Äôs transitional lifestyle and epidemiological conditions are reflected in gut microbiota compositions, and that these populations contain microbial diversity that remains to be described. This work underscores the critical need to broaden the scope of human gut microbiome research and include understudied, nonwestern populations to improve the relevance and accuracy of microbiome discoveries to broader populations.https://cassyni-user-files-prod.s3.amazonaws.com/KyY2XACqoDeYDKzqmes3FC https://cassyni.com/slides/outline/9yswy9NaxFXWeP6XXs91Em https://cassyni.com/events/9yswy9NaxFXWeP6XXs91Em/abstract https://cassyni-user-files-prod.s3.amazonaws.com/MLRvrZJ5cfsfj3AdMtariS https://cassyni.com/events/9yswy9NaxFXWeP6XXs91Em?videoPreview=1 A novel taurine-respiring murine gut bacterium contributes to colonization resistance against enteropathogensnohttps://cassyni.com/events/9yswy9NaxFXWeP6XXs91Em?videoPreview=12022-11-08T10:00:00+00:0064.12Microbiome Virtual International Forum Taurine-respiring gut bacteria produce H2S with ambivalent impact on host health. We report the isolation and genomic-ecophysiological characterization of the first taurine-respiring mouse gut bacterium. Taurinivorans muris represents a new widespread species with protective capacity against pathogens and differs from the human gut sulfidogen Bilophila wadsworthia in its sulfur metabolism and host distribution. Despite alternative physiologies, taurine respiration was the main in vivo lifestyle of T. muris independent of mouse diet and genotype. In gnotobiotic mice, T. muris selectively enhanced the activity of a sulfur metabolism gene-encoding prophage and provided slightly increased colonization resistance against Salmonella Typhimurium, which showed reduced expression of galactonate catabolism genes. We identified T. muris as the dominant sulfidogen of a mouse microbiota that conferred H2S-mediated protection against Klebsiella pneumoniae in a previous study. Together, we revealed the realized physiological niche of a key murine gut sulfidogen and its impact on pathogen and phage gene expression. Link to OA paper: https://www.biorxiv.org/content/10.1101/2022.10.05.510937v1https://cassyni-user-files-prod.s3.amazonaws.com/MLRvrZJ5cfsfj3AdMtariS https://cassyni.com/slides/outline/2a9tGtfiNPDg9oa4ZzHGpm https://cassyni.com/events/2a9tGtfiNPDg9oa4ZzHGpm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/W36rRrKs2dTkhZxBWZVtgW https://cassyni.com/events/2a9tGtfiNPDg9oa4ZzHGpm?videoPreview=1 Air quality on trains – aerodynamic interactions of exhaust and HVAC systemsnohttps://cassyni.com/events/2a9tGtfiNPDg9oa4ZzHGpm?videoPreview=12022-11-16T14:00:00+00:003395.04Department of Aeronautics and AstronauticsAir quality is known to have significant health impacts from both short- and long-term exposure. As a significant contributor, the transport sector is working to reduce its adverse impact; however, the impact of rail transport on air quality at local levels, particularly within enclosed spaces (e.g. stations and onboard trains), is still not fully understood. With ~30% of rail traction diesel-powered, previously studies have shown that in certain conditions pollution concentrations exceed prescribed EU limits in enclosed stations. Although these studies offer insight into issues at particular strategic locations, there have been none which address issues and identify mitigation measures to risks associated with poor air quality for both passengers and train crews onboard trains for typical journeys. This seminar will present work conducted as part of the Rail Safety and Standards Board (RSSB) Clean Air Research programme on project “T1234 Air Quality on Trains - HVAC and Exhaust Interactions Study”, which focused on providing better understanding of rail’s direct contribution to air pollution onboard trains. The project aimed to determine how exhaust emissions and heating, ventilation, and air conditioning (HVAC) systems interact and impact levels of air pollution onboard passenger trains, establishing factors that can be changed to improve air quality. The programme covered a wide range of techniques, from computational studies through to model- and full- experimental validation. Findings indicated that the design configuration of train roofs were particularly important when considering the interaction of exhaust gases with HVAC systems and that simple alterations in design and shape of the roof and exhaust pipe, as well as the HVAC placement and operation could lead to large improvements in onboard air quality Image credit: [K B (Unsplash)](https://unsplash.com/photos/black-steam-train-emitting-smoke-on-concrete-railway-during-daytime-W-j2QUiRnhk).https://cassyni-user-files-prod.s3.amazonaws.com/W36rRrKs2dTkhZxBWZVtgW https://cassyni.com/slides/outline/34oVKaKEoqmj9a6xARa565 https://cassyni.com/events/34oVKaKEoqmj9a6xARa565/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BhpGZrhETc1rg675nFGhH8 https://cassyni.com/events/34oVKaKEoqmj9a6xARa565?videoPreview=1 A systematic review of gut microbiota composition in observational studies of major depressive disorder, bipolar disorder and schizophrenianohttps://cassyni.com/events/34oVKaKEoqmj9a6xARa565?videoPreview=12022-04-12T14:00:00+00:0073.0Microbiome Virtual International Forum The emerging understanding of gut microbiota as ‘metabolic machinery’ influencing many aspects of physiology has gained substantial attention in the field of psychiatry. This is largely due to the many overlapping pathophysiological mechanisms associated with both the potential functionality of the gut microbiota and the biological mechanisms thought to be underpinning mental disorders. In this systematic review, we synthesised the current literature investigating differences in gut microbiota composition in people with the major psychiatric disorders, major depressive disorder (MDD), bipolar disorder (BD) and schizophrenia (SZ), compared to ‘healthy’ controls. We also explored gut microbiota composition across disorders in an attempt to elucidate potential commonalities in the microbial signatures associated with these mental disorders. Following the PRISMA guidelines, databases were searched from inception through to December 2021. We identified 44 studies (including a total of 2510 psychiatric cases and 2407 controls) that met inclusion criteria, of which 24 investigated gut microbiota composition in MDD, seven investigated gut microbiota composition in BD, and 15 investigated gut microbiota composition in SZ. Our syntheses provide no strong evidence for a difference in the number or distribution (α-diversity) of bacteria in those with a mental disorder compared to controls. However, studies were relatively consistent in reporting differences in overall community composition (β-diversity) in people with and without mental disorders. Our syntheses also identified specific bacterial taxa commonly associated with mental disorders, including lower levels of bacterial genera that produce short-chain fatty acids (e.g. butyrate), higher levels of lactic acid- producing bacteria, and higher levels of bacteria associated with glutamate and GABA metabolism. We also observed substantial heterogeneity across studies with regards to methodologies and reporting. Further prospective and experimental research using new tools and robust guidelines hold promise for improving our understanding of the role of the gut microbiota in mental and brain health and the development of interventions based on modification of gut microbiota. Link to OA paper: https://www.nature.com/articles/s41380-022-01456-3https://cassyni-user-files-prod.s3.amazonaws.com/BhpGZrhETc1rg675nFGhH8 https://cassyni.com/slides/outline/LrAs6p821gdiK8cxRyK8pD https://cassyni.com/events/LrAs6p821gdiK8cxRyK8pD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/J1RCH8NotXBW2nPZBUBc1t https://cassyni.com/events/LrAs6p821gdiK8cxRyK8pD?videoPreview=1 Cas9-Assisted Biological Containment of a Genetically Engineered Human Commensal Bacterium and Genetic Elementsnohttps://cassyni.com/events/LrAs6p821gdiK8cxRyK8pD?videoPreview=12024-04-17T11:00:00+00:0063.56Microbiome Virtual International Forum Sophisticated gene circuits built by synthetic biology can enable bacteria to sense their environment and respond predictably. Engineered biosensing bacteria outfitted with such circuits can potentially probe the human gut microbiome to prevent, diagnose, or treat disease. To provide robust biocontainment for engineered bacteria, we devised a Cas9-assisted auxotrophic biocontainment system combining thymidine auxotrophy, an Engineered Riboregulator (ER) for controlled gene expression, and a CRISPR Device (CD). The CD prevents the engineered bacteria from acquiring thyA via horizontal gene transfer, which would disrupt the biocontainment system, and inhibits the spread of genetic elements by killing bacteria harboring the gene cassette. This system tunably controlled gene expression in the human gut commensal bacterium Bacteroides thetaiotaomicron, prevented escape from thymidine auxotrophy, and blocked transgene dissemination. These capabilities were validated in vitro and in vivo. This biocontainment system exemplifies a powerful strategy for bringing genetically engineered microorganisms safely into biomedicine. Link to OA paper: https://www.nature.com/articles/s41467-024-45893-whttps://cassyni-user-files-prod.s3.amazonaws.com/J1RCH8NotXBW2nPZBUBc1t https://cassyni.com/slides/outline/CT7yCZcD9YJ11Ka65Z3dxh https://cassyni.com/events/CT7yCZcD9YJ11Ka65Z3dxh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5mLne2FQNDVFnckmxWYfD8 https://cassyni.com/events/CT7yCZcD9YJ11Ka65Z3dxh?videoPreview=1 Viroid-like colonists of human microbiomesnohttps://cassyni.com/events/CT7yCZcD9YJ11Ka65Z3dxh?videoPreview=12024-02-27T14:00:00+00:00672.96Microbiome Virtual International Forum Here, we describe the “Obelisks,” a previously unrecognised class of viroid-like elements that we first identified in human gut metatranscriptomic data. “Obelisks” share several properties: (i) apparently circular RNA about 1kb genome assemblies, (ii) predicted rod-like secondary structures encompassing the entire genome, and (iii) open reading frames coding for a novel protein superfamily, which we call the “Oblins”. We find that Obelisks form their own distinct phylogenetic group with no detectable sequence or structural similarity to known biological agents. Further, Obelisks are prevalent in tested human microbiome metatranscriptomes with representatives detected in about 7% of analysed stool metatranscriptomes (29/440) and in about 50% of analysed oral metatranscriptomes (17/32). Obelisk compositions appear to differ between the anatomic sites and are capable of persisting in individuals, with continued presence over 300 days observed in one case. Large scale searches identified 29,959 Obelisks (clustered at 90% nucleotide identity), with examples from all seven continents and in diverse ecological niches. From this search, a subset of Obelisks are identified to code for Obelisk-specific variants of the hammerhead type-III self-cleaving ribozyme. Lastly, we identified one case of a bacterial species (Streptococcus sanguinis) in which a subset of defined laboratory strains harboured a specific Obelisk RNA population. As such, Obelisks comprise a class of diverse RNAs that have colonised, and gone unnoticed in, human, and global microbiomes. https://cassyni-user-files-prod.s3.amazonaws.com/5mLne2FQNDVFnckmxWYfD8 https://cassyni.com/slides/outline/PKQtLEMeCyQCg56WyfDmY9 https://cassyni.com/events/PKQtLEMeCyQCg56WyfDmY9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Fmq2pwbgFJTwhbgQfbvk1k https://cassyni.com/events/PKQtLEMeCyQCg56WyfDmY9?videoPreview=1 Comparative Genomic and Metagenomic Investigations of the Corynebacterium tuberculostearicum Species Complex Reveals Potential Mechanisms Underlying Associations To Skin Health and Diseasenohttps://cassyni.com/events/PKQtLEMeCyQCg56WyfDmY9?videoPreview=12023-09-19T12:00:00+00:0057.16Microbiome Virtual International Forum Corynebacterium are a diverse genus and dominant member of the human skin microbiome. Recently, we reported that the most prevalent Corynebacterium species found on skin, including Corynebacterium tuberculostearicum and Corynebacterium kefirresidentii, comprise a narrow species complex despite the diversity of the genus. Here, we apply high-resolution phylogenomics and comparative genomics to describe the structure of the C. tuberculostearicum species complex and highlight genetic traits which are enriched or depleted in it relative to other Corynebacterium. Through metagenomic investigations, we also find that individual species within the complex can associate with specific body sites. Finally, we discover that one species from the complex, C. kefirresidentii, increases in relative abundance during atopic dermatitis flares, and show that most genomes of this species encode a colocalized set of putative virulence genes. Link to OA paper: https://journals.asm.org/doi/10.1128/spectrum.03578-22https://cassyni-user-files-prod.s3.amazonaws.com/Fmq2pwbgFJTwhbgQfbvk1k https://cassyni.com/slides/outline/Krsf1Spy8mXZeNnxKzqp1K https://cassyni.com/events/Krsf1Spy8mXZeNnxKzqp1K/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AiBb6wDYkMnzEhAjMwi5DG https://cassyni.com/events/Krsf1Spy8mXZeNnxKzqp1K?videoPreview=1 Microbiome in big pharma: Approach and applications in clinical trialsnohttps://cassyni.com/events/Krsf1Spy8mXZeNnxKzqp1K?videoPreview=12023-11-14T15:00:00+00:00724.0Microbiome Virtual International Forum No abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/AiBb6wDYkMnzEhAjMwi5DG https://cassyni.com/slides/outline/WEVLyoQzMP9zAt66M6nhgq https://cassyni.com/events/WEVLyoQzMP9zAt66M6nhgq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Jk2WMy9aK1yCd58WbvGpdt https://cassyni.com/events/WEVLyoQzMP9zAt66M6nhgq?videoPreview=1 Human milk oligosaccharides, antimicrobial drugs, and the gut microbiota of term neonates: observations from the KOALA birth cohort studynohttps://cassyni.com/events/WEVLyoQzMP9zAt66M6nhgq?videoPreview=12023-03-14T12:30:00+00:00680.04Microbiome Virtual International Forum The infant gut microbiota affects childhood health. This pioneer microbiota may be vulnerable to antibiotic exposures, but could be supported by prebiotic oligosaccharides found in breast milk and some infant formulas. We sought to characterize the effects of several exposures on the neonatal gut microbiota, including human milk oligosaccharides (HMOs), galacto-oligosaccharides (GOS), and infant/maternal antimicrobial exposures. We profiled the stool microbiota of 1023 one-month-old infants from the KOALA Birth Cohort using 16S rRNA gene amplicon sequencing. We quantified 15 HMOs in breast milk from the mothers of 220 infants, using high-performance liquid chromatography-mass spectrometry. Both breastfeeding and antibiotic exposure decreased gut microbial diversity, but each was associated with contrasting shifts in microbiota composition. Other factors associated with microbiota composition included C-section, homebirth, siblings, and exposure to animals. Neither infant exposure to oral antifungals nor maternal exposure to antibiotics during pregnancy were associated with infant microbiota composition. Four distinct groups of breast milk HMO compositions were evident, corresponding to maternal Secretor status and Lewis group combinations defined by the presence/absence of certain fucosylated HMOs. However, we found the strongest evidence for microbiota associations between two non-fucosylated HMOs: 6’-sialyllactose (6’-SL) and lacto-N-hexaose (LNH), which were associated with lower and higher relative abundances of Bifidobacterium, respectively. Among 111 exclusively formula-fed infants, the GOS-supplemented formula was associated with a lower relative abundance of Clostridium perfringens. In conclusion, the gut microbiota is sensitive to some prebiotic and antibiotic exposures during early infancy and understanding their effects could inform future strategies for safeguarding a health-promoting infant gut microbiota. Link to OA paper: https://doi.org/10.1080/19490976.2022.2164152https://cassyni-user-files-prod.s3.amazonaws.com/Jk2WMy9aK1yCd58WbvGpdt https://cassyni.com/slides/outline/Wj8x2V4Wnqi3AecywY5Vx9 https://cassyni.com/events/Wj8x2V4Wnqi3AecywY5Vx9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Wn5Fzso9gpHrXq8dMmNxDc https://cassyni.com/events/Wj8x2V4Wnqi3AecywY5Vx9?videoPreview=1 High Reynolds number turbulent drag reduction by spanwise wall forcingnohttps://cassyni.com/events/Wj8x2V4Wnqi3AecywY5Vx9?videoPreview=12023-11-15T11:00:00+00:003339.04Department of Aeronautics and AstronauticsTurbulent friction drag is an inevitable source of power consumption for aircrafts, trains, pipelines, and many other industrial applications. Significant efforts are ongoing to design and study drag-reducing mechanisms, e.g. riblets, superhydrophobic surfaces and blowing/suction. In this seminar, I focus on an active controlling mechanism based on spanwise surface oscillation, leading to the generation of a streamwise travelling wave. The mechanism has been extensively studied via direct numerical simulation (DNS); it has shown the potential to reduce drag by 40%. Owing to the expensive computational cost of DNS, the prediction models for drag reduction are derived based on datasets with friction Reynolds numbers less than 2000. Motivated by Intellectual Ventures, a team of researchers have built their experimental and large-eddy simulation capabilities to study the travelling wave actuation at friction Reynolds numbers beyond 10000. Thus, providing the opportunity to study the efficacy of this mechanism at a flow regime closer to that of ground and air vehicles. As a member of this team, I present our findings. My presentation evolves around two major themes: 1) Do the high Reynolds number data agree with the past prediction models? If not, what emerging flow physics are related to the disagreement? 2) Stokes layer is an important mechanism in this problem. How does this mechanism interact with the near-wall turbulence? and how this interaction manifests in the drag reduction?https://cassyni-user-files-prod.s3.amazonaws.com/Wn5Fzso9gpHrXq8dMmNxDc https://cassyni.com/slides/outline/RJ1JWxwjxocxmnNkLd5hxh https://cassyni.com/events/RJ1JWxwjxocxmnNkLd5hxh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EdKjtpq6bckUtfwPsgH8Xg https://cassyni.com/events/RJ1JWxwjxocxmnNkLd5hxh?videoPreview=1 Recent Advancements in Charged Particle Technology for Practical Applications from Drag Reduction to Disinfectionnohttps://cassyni.com/events/RJ1JWxwjxocxmnNkLd5hxh?videoPreview=12024-10-25T12:00:00+00:003660.96Department of AeronauticsWeakly or partially ionized air plasma remains an area of strong research interest due to its broad practical relevance. Besides local flow modification for lift, drag, surface heat flux, turbulence, and noise control, these charged particles have shown excellent efficacy for biological decontamination for space and medical applications. At the heart of this charged particle technology is a set of electrodes separated by sufficient potential difference across a suitable dielectric medium to produce reactive species including short-lived metastables and charged particles. A range of electrical and geometric parameters determines the effective coupling of these charged particles with the neighboring working gas and/or surfaces. We will discuss key findings, advancements, and challenges for select practical applications of this charged particle technology. Realizable performance issues of the electrodes under adverse ambient conditions will also be discussed.https://cassyni-user-files-prod.s3.amazonaws.com/EdKjtpq6bckUtfwPsgH8Xg https://cassyni.com/slides/outline/62ijiJiGqx261CLFRKVQGV https://cassyni.com/events/62ijiJiGqx261CLFRKVQGV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BHMLkpAxnDtVKMNBGTpEii https://cassyni.com/events/62ijiJiGqx261CLFRKVQGV?videoPreview=1 A scoping review of qualitative studies on sexual and reproductive health and rights in Uganda: Exploring factors at multiple levelsnohttps://cassyni.com/events/62ijiJiGqx261CLFRKVQGV?videoPreview=12024-09-23T12:00:00+00:00633.24Women's Health**Background:** Uganda is burdened by high unintended and teen pregnancies, high sexually transmitted infections, and harm caused by unsafe abortion. **Objectives:** Explore factors influencing sexual and reproductive health and rights (SRHR) in Uganda by synthesizing evidence from qualitative studies using a scoping review. **Eligibility criteria:** Original qualitative peer-reviewed research studies published between 2002 and 2023 in any language exploring factors influencing SRHR in Uganda. **Sources of evidence:** Eight databases searched using qualitative/mixed methods search filters and no language limits. **Charting methods:** Information extracted included author, article title, publication year, study aims, participant description, data collection type, sample size, main findings, factors at the individual, interpersonal, community, and policy levels, implications for SRHR in Uganda, and study limitations. Quality of the selected articles was assessed using the Critical Appraisal Skills Programme tool. **Results:** One hundred and seventy-three studies met inclusion criteria. At the individual level, knowledge and attitudes towards SRHR, risky sexual behavior, and access to maternal SRHR services were identified as critical factors influencing health outcomes. Interpersonal factors included communication with sexual partners and relationships with family, school, and community members. Healthcare organization factors included adolescent access to education, SRHR services, and HIV prevention. Cultural and social factors included gendered norms and male involvement in SRHR. Policy-level factors included the importance of aligning policy and practice. **Conclusions:** Multiple factors at individual, interpersonal, community, healthcare, cultural and policy levels were found to influence SRHR in Uganda. The findings suggest that interventions targeting multiple levels of the socio-ecological system may be necessary to improve SRHR outcomes. This review highlights the need for a holistic approach that considers the broader socio-ecological context. Reducing identified gaps in the literature, particularly between policy and practice related to SRHR, is urgently needed in Uganda. We hope this review will inform the development of policies and interventions to improve SRHR outcomes. **Keywords:** Reproductive health; sexual and reproductive health and rights (SRHR); qualitative research; scoping review; Ugandahttps://cassyni-user-files-prod.s3.amazonaws.com/BHMLkpAxnDtVKMNBGTpEii https://cassyni.com/slides/outline/XDWKvsZBCgzsNrx5bPscBX https://cassyni.com/events/XDWKvsZBCgzsNrx5bPscBX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DEBvuDhtsBymwmAMm6tDMY https://cassyni.com/events/XDWKvsZBCgzsNrx5bPscBX?videoPreview=1 Comparative Analysis of Energy Harvesting from Hybrid Bistable Symmetric Laminates Using Piezoelectric Patchesnohttps://cassyni.com/events/XDWKvsZBCgzsNrx5bPscBX?videoPreview=12025-06-24T10:00:00+00:00796.04NODYSThis study experimentally examines the energy harvesting potential of a hybrid bistable symmetric laminate (HBSL) with a cantilever boundary condition. Two MFC-d31 patches i.e., (i) Small patch (28×7×0.3) mm3 and (ii) Big patch (85×7×0.3) mm3 are attached with two fabricated HBSL in unimorph configuration, and their harvested power densities (Power per unit volume of MFC patch) are compared. Frequency sweeps are performed for both the laminates at various excitation amplitudes, and the softening effect is observed from the harvested power density response curve. The results indicate that the larger patch experiences more strain change during vibration, leading to higher harvested energy per unit piezoelectric patch volume.https://cassyni-user-files-prod.s3.amazonaws.com/DEBvuDhtsBymwmAMm6tDMY https://cassyni.com/slides/outline/Tky6c62W8V8EMAeWwjVeeh https://cassyni.com/events/Tky6c62W8V8EMAeWwjVeeh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/92gJ1Qhw8oGwjN9uS2qjj4 https://cassyni.com/events/Tky6c62W8V8EMAeWwjVeeh?videoPreview=1 Stabilization of Time Delayed Stochastic Jump Discontinuous Systems Driven by Poisson Noisenohttps://cassyni.com/events/Tky6c62W8V8EMAeWwjVeeh?videoPreview=12025-07-08T15:00:00+00:00724.12NODYSIn this paper, stabilizing control function is designed for nonlinear strict-feedback stochastic systems influenced by time delay and random jump discontinuous process in the form of Poisson noise. The backstepping method is employed to design the control which globally asymptotically stabilizes the system at the origin in probability. A numerical example is illustrated to prove the proposed theoretical results.https://cassyni-user-files-prod.s3.amazonaws.com/92gJ1Qhw8oGwjN9uS2qjj4 https://cassyni.com/slides/outline/6X67chCwFoJvDQfM5BHWVs https://cassyni.com/events/6X67chCwFoJvDQfM5BHWVs/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Bd5iVzrSSTBTWYxF773W5t https://cassyni.com/events/6X67chCwFoJvDQfM5BHWVs?videoPreview=1 Towards early bowel cancer detection: A data driven dynamic method of lesions characterisation using a robotic capsulenohttps://cassyni.com/events/6X67chCwFoJvDQfM5BHWVs?videoPreview=12025-06-24T11:00:00+00:00767.36NODYSThis study aims to improve early bowel cancer detection by introducing a non-visual approach to lesion characterisation, with a focus on precision and reliability. The study makes use of the sensitive dynamics of a robotic capsule self-propelling in the bowel to biomechanically characterise encountered lesions. The method incorporates a two-phase machine learning involving supervised regression as first phase and unsupervised clustering as final phase. The initial phase employs multi-layer perceptron (MLP), support vector regression, and Gaussian process regression to predict the stiffness of lesions, expressed as Young’s modulus (E) from capsule displacement signals. The final phase involving Gaussian mixture model (GMM) clustering achieved over 89 % accuracy for both simulation and experiment. The GMM demonstrated improved precision and reliability when incorporating predictions from more accurate regression models, such as MLP, though it struggled with high and closely related E-values.https://cassyni-user-files-prod.s3.amazonaws.com/Bd5iVzrSSTBTWYxF773W5t https://cassyni.com/slides/outline/JNgEqjFRC9XjK7e1EGrFgy https://cassyni.com/events/JNgEqjFRC9XjK7e1EGrFgy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/55VTdwXjd8qnwhhE2vFh8A https://cassyni.com/events/JNgEqjFRC9XjK7e1EGrFgy?videoPreview=1 Instability of a High-Speed Moving Mass Suspended Magnetically from a Periodically Supported Beamnohttps://cassyni.com/events/JNgEqjFRC9XjK7e1EGrFgy?videoPreview=12025-07-09T16:00:00+00:001211.6NODYSThe current study addresses the stability of a moving mass suspended magnetically from a periodically supported beam. The stability of the free vibration about the periodic steady state has been studied. Findings employing periodic solutions to determine the stability boundary show that the shape of the stable domain resembles, or not, that predicted by the model that includes a beam with distributed constant support stiffness, depending on the magnitude of the bending stiffness relative to the stiffness of the discrete supports; the size of the elliptical parametric-resonance zones that indent the stable domain also vary with this stiffness ratio.https://cassyni-user-files-prod.s3.amazonaws.com/55VTdwXjd8qnwhhE2vFh8A https://cassyni.com/slides/outline/Ev91Wwik7wedXDiDRbZ1MP https://cassyni.com/events/Ev91Wwik7wedXDiDRbZ1MP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RYrb1MUY1d13CngKdmBKwC https://cassyni.com/events/Ev91Wwik7wedXDiDRbZ1MP?videoPreview=1 Turbulence-Modified Safety Factor Profile in Tokamaks with Low Magnetic Shearnohttps://cassyni.com/events/Ev91Wwik7wedXDiDRbZ1MP?videoPreview=12025-03-13T15:00:00+00:001574.88Journal of Plasma PhysicsIn this work, we investigate the impact of electromagnetic effects on plasma turbulence self-organization at low magnetic shear using nonlinear gyrokinetics simulations. Previous electrostatic studies showed that turbulent eddies can extend along magnetic field lines for hundreds of poloidal turns when the magnetic shear $\hat{s}$ is low or zero. Under these conditions, parallel self-interaction induces strong corrugations in plasma profiles at multiple low-order rational surfaces, including the formation of stationary current layers. When magnetic shear is low and electromagnetic effects are considered, these turbulence-generated currents locally flatten the safety factor profile to form staircase structures. This feedback mechanism between turbulence and the imposed safety factor profile results in a significant reduction of turbulent transport. To further explore this interaction, we employed a novel extension of the flux tube model, allowing simulations of non-uniform magnetic shear profiles, including $q$ profiles with reversed magnetic shear relevant to Internal Transport Barrier (ITB) formation. Our findings indicate that turbulence-generated current layers “pull” the safety factor profile toward rational values, thereby broadening the safety factor profile minimum and enhancing the turbulent stabilization. We believe these results are key in ITB formation, can inform long-standing experimental observations, and are important for the design of low magnetic shear fusion devices.https://cassyni-user-files-prod.s3.amazonaws.com/RYrb1MUY1d13CngKdmBKwC https://cassyni.com/slides/outline/9V1N1RbyHuZZ8MTypgZDMw https://cassyni.com/events/9V1N1RbyHuZZ8MTypgZDMw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UGRQm7XvRe3d5SZfMKZxDC https://cassyni.com/events/9V1N1RbyHuZZ8MTypgZDMw?videoPreview=1 First Laboratory Observations of Residual Energy Generation in Strong Alfvén Wave Interactionsnohttps://cassyni.com/events/9V1N1RbyHuZZ8MTypgZDMw?videoPreview=12024-09-19T15:00:00+00:002404.92Journal of Plasma PhysicsIn the MHD inertial range (scales larger than ion-kinetic scales) turbulent fluctuations in the solar wind are often Alfvénic in character, meaning that their magnetic and flow velocity fluctuations are proportional to each other and predominantly perpendicular to the background magnetic field. However, observations of the solar wind have shown that there is a significant difference in the energy in velocity fluctuations and normalized magnetic fluctuations. This difference, called the residual energy, should be zero for linear Alfvén waves, but is consistently observed to be negative in the solar wind, with magnetic fluctuations dominating. This work investigates the energy partition in strong three-wave interactions through an experimental campaign on the LArge Plasma Device (LAPD) in an MHD-like regime. Primary (driven) modes are launched from antennas, and secondary modes generated by the strong three-wave interaction are observed. The primary modes are shown to have no residual energy, while the secondary modes have significant residual energy - negative in the “sum” mode and positive in the “difference” mode. These results constitute the first laboratory demonstration that residual energy can indeed be generated by nonlinear mode coupling.https://cassyni-user-files-prod.s3.amazonaws.com/UGRQm7XvRe3d5SZfMKZxDC https://cassyni.com/events/MqF6H9HyfiL9AWQC5c4P8h/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WXKYJieudY166ucumgUFXt https://cassyni.com/slides/outline/QJV7WZXbs16dXSskdHy1rd https://cassyni.com/events/QJV7WZXbs16dXSskdHy1rd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BG4bcgwKv3LxMiSg296FxA https://cassyni.com/events/QJV7WZXbs16dXSskdHy1rd?videoPreview=1 Evolution of current end vorticity sheets in collisionless plasma turbulencenohttps://cassyni.com/events/QJV7WZXbs16dXSskdHy1rd?videoPreview=12022-11-03T15:00:00+00:002680.64Journal of Plasma PhysicsThe evolution of current and vorticity sheets in collisionless plasmas, where magnetic reconnection within turbulence may take place driven by the electron inertia, is studied. We start from a linear analysis of magnetic vs. fluid instability, that might affect these layers, to understand the complex situation that generates in a turbulent plasma. Here, due to the presence of strong velocity shears, the typical plasmoids formation, observed to influence the energy cascade in the resistive magnetohydrodynamic context, has to coexist with the Kelvin-Helmholtz instability. We find that the current density layers may undergo the plasmoid or the Kelvin-Helmholtz instability depending on the local values of the magnetic and velocity fields. The competition among these instabilities affects not only the evolution of the current sheets, that may generate plasmoid chains or Kelvin-Helmholtz-driven vortices, but also the energy cascade, that is different for the magnetic and kinetic spectra.https://cassyni-user-files-prod.s3.amazonaws.com/BG4bcgwKv3LxMiSg296FxA https://cassyni.com/slides/outline/Gtm3pJpjH8o7mQgr58MPQZ https://cassyni.com/events/Gtm3pJpjH8o7mQgr58MPQZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HtoinkwuD2RCYwGXLDd4Xg https://cassyni.com/events/Gtm3pJpjH8o7mQgr58MPQZ?videoPreview=1 Prospects for real-time, first-principles transport simulations and stellarator optimization including turbulencenohttps://cassyni.com/events/Gtm3pJpjH8o7mQgr58MPQZ?videoPreview=12022-06-09T15:00:00+00:003281.88Journal of Plasma PhysicsThe open-source Trinity code solves for the time-dependent radial profiles of density, temperature, etc, using turbulent fluxes obtained from any radially local gyrokinetic turbulence code, neoclassical fluxes obtained from any drift kinetic solver, external sources, and edge boundary conditions supplied by the user. While originally developed for tokamak applications, the multiscale approach of Trinity is easily generalized for stellarator applications, as long as the equilibrium is assumed to consist of nested flux surfaces without islands. We present results using the original Trinity code together as well as a new Python version that will enable broader, easier uptake by the community. In 2018, we embedded Trinity into an optimization framework and demonstrated the ability to optimize tokamak shaping to maximize fusion power using first-principles estimates for turbulence-induced fluxes. Here, we will present our approach to embedding these gyrokinetic tools into the SIMSOPT framework. GX is an open-source, radially-local, GPU-native, gyrokinetic turbulence code that uses pseudo-spectral methods and native CUDA libraries to calculate turbulence-induced fluxes and critical gradients. At high resolution, GX is simply yet another GK code, but it can be run successfully at low resolution, in lieu of uncontrolled approximations and reduced models. With these tools, we demonstrate the ability to solve for the time-dependent evolution of core fusion reactor profiles in approximately real time, without resorting to reduced models. We also demonstrate the ability to find a shape, size, etc, that maximizes fusion performance by minimizing turbulence-induced losses “inside the optimization loop” for families of tokamak and stellarator reactor concepts, using equilibrium information calculated by VMEC and/or a near-axis expansion approximation, and we present machine-learned, sub-grid techniques that could further accelerate these calculations. I will show linear and nonlinear benchmarks against standard codes from the community, for both tokamak and stellarator configurations. Finally, we introduce the concept of specific computational intensity and use it to demonstrate how one can decide when to retire a given reduced model and rely instead on a higher-fidelity approach. There are many, many reduced models available for modeling fusion plasmas and without some kind of easy-to-use, objective method to distinguish the appropriateness of one approach from another, modelers and designers are often left to work out how to proceed more or less randomly. This leads to severe combinatoric complexity in design and interpretation efforts, which we hope to help bring under control.https://cassyni-user-files-prod.s3.amazonaws.com/HtoinkwuD2RCYwGXLDd4Xg https://cassyni.com/events/KN153j4MURZc8MAQcpG28V/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LN3k2BBXQKBgusk5suXhFc https://cassyni.com/events/XiDBCpEUSsQU22QDbApkGd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/F3meWuJtFg3y3i9CXHa7YS https://cassyni.com/slides/outline/SH5XhJ7hcqKPdA9yzFpxHB https://cassyni.com/events/SH5XhJ7hcqKPdA9yzFpxHB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TePf9AXBZUHe76WBBYtz2z https://cassyni.com/events/SH5XhJ7hcqKPdA9yzFpxHB?videoPreview=1 Fast and furious: reconnection and turbulence in magnetically-dominated astrophysical plasmasnohttps://cassyni.com/events/SH5XhJ7hcqKPdA9yzFpxHB?videoPreview=12022-02-17T16:00:00+00:002984.28Journal of Plasma PhysicsIn the most powerful astrophysical sources, reconnection and turbulence operate in the “relativistic” regime, where the magnetic field energy exceeds even the rest mass energy of the plasma. Here, reconnection and turbulence can lead to fast dissipation rates and efficient particle acceleration, thus being prime candidates for powering the observed fast and bright flares of high-energy non-thermal emission. With fully-kinetic particle-in-cell (PIC) simulations and analytical theory, we investigate the physics of relativistic reconnection and turbulence, and demonstrate that they can be the “engines” behind: (1) high-energy flares in blazar jets; and (2) the hard-state spectra of black hole X-ray binaries and Active Galactic Nuclei.https://cassyni-user-files-prod.s3.amazonaws.com/TePf9AXBZUHe76WBBYtz2z https://cassyni.com/events/Smj8jymE4HsScvgsah7kYV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2FiRF4XD5y9Vm1VAeLjR1Y https://cassyni.com/events/5Xr9kawfBc48VAhhi8ucPf/abstract https://cassyni.com/slides/outline/BwDM1Ymoar4CiiqzybMuQy https://cassyni.com/events/BwDM1Ymoar4CiiqzybMuQy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4TFdJnk7HQ5YjgwXqf7Aj8 https://cassyni.com/events/BwDM1Ymoar4CiiqzybMuQy?videoPreview=1 Angioplasty for Renal Artery Stenosis in Childrennohttps://cassyni.com/events/BwDM1Ymoar4CiiqzybMuQy?videoPreview=12025-10-14T09:48:32+00:00672.68Society for Pediatric Interventional Radiology## Introduction Renal artery stenosis (RAS) is a rare but important cause of hypertension in children patients. Percutaneous renal angioplasty (PTRA) offers a minimally invasive therapeutic option, but data on its efficacy in children remain limited, particularly if associated with mid-aortic stenosis. ## Materials and Methods This retrospective study included children with hypertension secondary to RAS who underwent PTRA at a tertiary care pediatric hospital. Data on patient characteristics, procedural details, and outcomes were collected. Clinical success was defined as improved blood pressure control or reduction in antihypertensive use. Technical success was categorized as complete (<25% residual stenosis) or partial (25–69% residual stenosis) resolution. Descriptive and subgroup analyses were performed. ## Results Fifteen patients (mean age 10.1 ± 4.2 years, 8 males) underwent 20 angioplasties. Five patients (33.3%) had mid-aortic syndrome (MAS). Most stenoses were right-sided (40%), with 26.7% bilateral. Hypertension was incidentally diagnosed in 73.3% of cases. Non-cutting balloons were used in 95% of procedures, and minor complications occurred in two cases (hematoma, intimal dissection). Clinical success was achieved in all procedures (100%), while technical success was complete in 60% and partial in 40%. Subgroup analysis showed no significant difference in outcomes between MAS-associated and isolated RAS. ## Discussion Percutaneous renal angioplasty is a safe and effective treatment for RAS in children, with high clinical success and acceptable technical outcomes.https://cassyni-user-files-prod.s3.amazonaws.com/4TFdJnk7HQ5YjgwXqf7Aj8 https://cassyni.com/slides/outline/auvQnQSJBxtRsCGAnWhwj https://cassyni.com/events/auvQnQSJBxtRsCGAnWhwj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/YG258vjj1BxCE1nBoUpG8e https://cassyni.com/events/auvQnQSJBxtRsCGAnWhwj?videoPreview=1 From bluff-body flows to performance enhancement of tidal turbinesnohttps://cassyni.com/events/auvQnQSJBxtRsCGAnWhwj?videoPreview=12024-10-02T13:00:00+00:003065.08Department of Aeronautics and AstronauticsThe first part of the talk will focus on my doctoral research, which aims to understand the mechanism of unsteady flow and thrust generation in the flow field of an oscillating cylinder filament system through detailed flow visualization and particle image velocimetry measurements. Fluid structure interaction is ubiquitous in nature. For example, fish swim and birds fly by making use of an intricately coupled interaction between their body and the surrounding flow field. In addition, the flexibility in their wings and tails aid in enhancing thrust and maximizing propulsive efficiency. Some marine animals like tadpoles have a circular head that resembles a bluff body. In addition, they have a flexible tail. They propel themselves forward by oscillating both their head and tail. In this work we approximately model the motion of a ‘tethered tadpole’ by studying the flow past a rotationally oscillating cylinder with an attached flexible filament. The streamwise force and power are estimated through control volume analysis using an improved expression which considers the streamwise and transverse velocity fluctuations in the wake. These terms become important in a flow field where asymmetric wakes are observed. An attached filament significantly modifies the flow past an oscillating cylinder-filament system from a Bénard Kármán vortex street to a reverse Bénard Kármán vortex street, albeit over a certain range of Strouhal number ~ 0.25 - 0.5, encountered in nature, in flapping flight and in the flow past pitching airfoils. The transition from a Kármán vortex street to a reverse Kármán vortex street precedes the drag-to-thrust transition. Most of the momentum and energy addition in the flow field happens near the filament tip, which indicates that filament oscillation is responsible for thrust generation. Maximum thrust is generated at the time instants when vortices are shed in the wake from the filament tip. The second part of the talk will focus on my postdoctoral research at The University of Edinburgh. The aim of the project is to investigate the effectiveness of passively pitching blades on tidal turbine performance. Tidal energy is a reliable and sustainable source of renewable energy that can contribute towards energy security. Tidal turbine blades experience large unsteady load fluctuations due to flow unsteadiness, turbulence, yaw and shear of the oncoming flow, which may lead to structural fatigue. In order to operate over a wide range of conditions, many turbines adopt an active collective pitch control system, where the blades pitch simultaneously, to ensure that the turbine can self-start when the flow velocity is slow, cap the maximum power to protect the generator when the flow velocity is high, and stop the turbine in case of emergency. However, active pitch control systems require complex pitch mechanisms and gear boxes which can increase the need for frequent maintenance, operational costs and potential for failure. Here, we present a passive pitch system, where a torque is applied at the blade root, by means of a mechanical spring such that the blade pitch varies in response to the hydrodynamic moment. In this talk, we demonstrate through experiments that for any flow velocity, there is a combination of spring stiffness and preload that allow a passive pitch blade to generate the same mean power and thrust than a fixed pitch blade. When the turbine is operated at higher tip speed ratios (λ) than the design condition, the power remains about constant while the thrust and the thrust fluctuations decrease significantly (up to 40% for a 20% increase in λ). If λ is further increased, the power decreases at higher rate than a fixed pitch turbine. Therefore, the angular velocity of a passive pitch blade can be increased to cap the maximum power when the flow velocity is higher than rated conditions. These results demonstrate that passive pitch can potentially replace active pitch without compromising performance and potentially increasing reliability.https://cassyni-user-files-prod.s3.amazonaws.com/YG258vjj1BxCE1nBoUpG8e https://cassyni.com/slides/outline/Rni9nud3Cz2ZRFQjJEeBGy https://cassyni.com/events/Rni9nud3Cz2ZRFQjJEeBGy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7wAns3p6P3ZYJ6Jis2jZ7c https://cassyni.com/events/Rni9nud3Cz2ZRFQjJEeBGy?videoPreview=1 Evidence-based Recommendations For ESOs to Foster Meaningful Black Business Growthnohttps://cassyni.com/events/Rni9nud3Cz2ZRFQjJEeBGy?videoPreview=12024-11-20T18:00:00+00:00812.32Center for Black Entrepreneurship, Spelman College# Introduction Entrepreneurship has long been recognized as a pathway to wealth creation, particularly for marginalized communities seeking economic empowerment. For Black households, business ownership is seen as a means to overcome systemic barriers and constraints. Yet, despite the potential for wealth creation, the racial wealth gap remains persistent. Black-owned businesses contribute significantly to the economy, but their share of revenues in high-growth industries remains disproportionately small. Structural inequities, such as limited access to capital and systemic discrimination, hinder their ability to scale and thrive. The urgency of this issue has drawn attention to the role of entrepreneurial support organizations (ESOs) in mitigating these barriers. Investments in Black entrepreneurship have increased in recent years, but entrepreneurship education, often heralded as a key driver of business success, remains under-researched and unproven (Koropogui et al., 2024; Bauman & Lucy, 2021). Moreover, clear frameworks for entrepreneurial success are scarce (Aldrich & Yang, 2012). This study seeks to address these gaps by exploring effective mechanisms for supporting Black entrepreneurs and evaluating the role of ESOs in fostering equitable economic opportunities. # Methods The study adopted a two-part approach to examine the challenges Black entrepreneurs face and the mechanisms that could address them. ## 1. Secondary Data Analysis Data from the Black Wealth Data Center, Federal Reserve, and Brookings Institution were analyzed to identify systemic barriers to wealth creation for Black entrepreneurs. This analysis provided foundational insights into disparities in industry representation, access to capital, and other structural constraints. Key findings revealed that Black-owned businesses account for only 0.1% of revenues in the top three revenue-generating industries (utilities, wholesale trade, and manufacturing), highlighting significant underrepresentation in high-growth sectors. ## 2. Quasi-Experimental Study A survey of 617 Black entrepreneurs conducted at an ESO in a southeastern US city provided quantitative and qualitative data on entrepreneurial outcomes. Participants were divided into a treatment group (227 entrepreneurs engaged in programming at the ESO) and a control group (390 entrepreneurs who had not engaged with that ESO). This design allowed for a comparative analysis of the impact of a particular ESO framework on business success. # Results The study yielded critical insights into the challenges and opportunities for wealth creation among Black entrepreneurs: ## 1. Systemic Challenges to Wealth Creation • Black entrepreneurs face significant barriers to wealth creation, including limited representation in high-revenue industries and inequitable access to capital. • Wealth-building through business equity is disproportionately inaccessible to Black entrepreneurs compared to other racial and ethnic groups. ## 2. Diverse Entrepreneurial Motivations • The survey revealed that Black entrepreneurs pursue business ownership for diverse reasons, often prioritizing community change (39%) and personal well-being (30%) over direct wealth creation. These motivations underscore the need for ESOs to align their programming with the varied goals of Black entrepreneurs. # 3. Impact of Support Systems • A business readiness diagnostic provided a nuanced understanding of entrepreneurial strengths and weaknesses. Black entrepreneurs excelled in storytelling and vision-setting but faced challenges in scaling, customer acquisition, and risk management. • Entrepreneurs participating in programming at the ESO significantly outperformed their peers in several key areas: o Revenue Generation: Doubling the revenue of the control group. o Job Creation: Supporting 2.7 times more full-time jobs than their peers. o Personal Earnings: Achieving 2.2 times higher personal earnings from their businesses. # Discussion The findings emphasize the critical role of ESOs in addressing systemic barriers and fostering economic success for Black entrepreneurs. While the systemic challenges to wealth creation are deeply rooted, targeted interventions and community-based support can significantly enhance entrepreneurial outcomes. ## 1. Addressing Structural Barriers The underrepresentation of Black entrepreneurs in high-revenue industries highlights the importance of guiding business owners toward sectors with greater wealth-creation potential. ESOs must also address the persistent capital access gap by advocating for equitable funding mechanisms and providing resources to reduce startup costs. ## 2. Aligning Programming with Entrepreneurial Goals The diversity of entrepreneurial motivations observed in this study underscores the need for tailored support systems. ESOs can enhance their impact by offering programming tracks that align with specific goals, such as community-driven initiatives, personal well-being, or wealth- oriented entrepreneurship. ## 3. Leveraging Diagnostic Tools for Targeted Support The business readiness diagnostic proved instrumental in identifying growth barriers, such as scalability and customer acquisition, and tailoring interventions to address these challenges. ESOs should adopt and refine such tools to provide hyper-targeted support for entrepreneurs. ## 4. Building Community-Based Ecosystems The success of the ESO programming demonstrates the transformative potential of community- driven support systems. By fostering connections to mentors, partners, and customers, ESOs can create ecosystems that amplify economic activity and entrepreneurial success. The relational capital developed through these networks is particularly critical for Black entrepreneurs, who often face systemic exclusion from traditional business networks.https://cassyni-user-files-prod.s3.amazonaws.com/7wAns3p6P3ZYJ6Jis2jZ7c https://cassyni.com/events/JrGBYVKGKttAiccjEGCwNV/seminar/qa https://cassyni.com/slides/outline/JrGBYVKGKttAiccjEGCwNV https://cassyni.com/events/JrGBYVKGKttAiccjEGCwNV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LYrQteqdpm2mnYUoE3hsTt https://cassyni.com/events/JrGBYVKGKttAiccjEGCwNV?videoPreview=1 REACH Casual Friday: Self-Leadership Frameworknohttps://cassyni.com/events/JrGBYVKGKttAiccjEGCwNV?videoPreview=12026-01-23T18:00:00+00:002097.04Research Evaluation and Analytics Capacity Hub## This month's Casual Friday Topic: Self-Leadership - Turning Expertise into Trust In research analytics, influence grows not just from technical insight but from how you show up in the room. This session presents a trust-based leadership model—listen, understand, persuade—that helps participants translate expertise into credibility and build mutual trust with colleagues and leadership.https://cassyni-user-files-prod.s3.amazonaws.com/LYrQteqdpm2mnYUoE3hsTt https://cassyni.com/slides/outline/KMtabCzoryrhYjxeSP7aqB https://cassyni.com/events/KMtabCzoryrhYjxeSP7aqB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EuRtKdyEuWeT7KH1N6hn86 https://cassyni.com/events/KMtabCzoryrhYjxeSP7aqB?videoPreview=1 Rational design of ZIF based hierarchical structures for environment remediation and antibacterial application.nohttps://cassyni.com/events/KMtabCzoryrhYjxeSP7aqB?videoPreview=12022-10-04T13:00:00+00:003766.8ElsevierZeolite Imidazolate Frameworks (ZIF) can be used in a wide range of applications, such as water treatment, molecular sieving, gas adsorption, drug delivery, and catalysis. However, their fabrications in primarily aqueous environments have succumbed to large chemical consumption and have been challenging in sustainable manufacturing. Water-organic cosolvent system enables ZIF fabrications at low ligand-to-metal ratios and the resulting ZIF materials with interesting nanostructures and surface properties. Based on the syntheses involving various cosolvents including alcohols, ketones, and amides, we systematically studied their impacts on ZIF (ZIF-L/ZIF-8 as examples) crystallization, phase transformation, morphological evolution, surface wettability, separation, and antibacterial performance. Formation mechanisms were proposed for many cosolvent systems in terms of solvent properties, metal site interactions, and deprotonation capabilities, providing new insights into the solvent's roles in ZIF nucleation and crystal growth. Additionally, we explored a number of in-situ fabrications of ZIF-L and/or ZIF-8 on various substrates including organic (nylon membrane, 3D printed mesh, melamine sponge, and mask filter layer) and inorganic (stainless steel and ceramics) materials, and evaluated their performance on wastewater treatment (e.g., oil/water separation, oil adsorption), small molecules distinguishing (e.g., dye removal) and antibacterial activities. This series of our recent studies could provide useful information for researchers working on MOF design, crystal structure control, and composite materials synthesis.https://cassyni-user-files-prod.s3.amazonaws.com/EuRtKdyEuWeT7KH1N6hn86 https://cassyni.com/slides/outline/4YSTChb4hFF5EofwRjHrHT https://cassyni.com/events/4YSTChb4hFF5EofwRjHrHT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5s6px6T25UThnoBQnothB4 https://cassyni.com/events/4YSTChb4hFF5EofwRjHrHT?videoPreview=1 Infection transmission in the built environment - the interface of biology, fluid dynamics, design and human behaviournohttps://cassyni.com/events/4YSTChb4hFF5EofwRjHrHT?videoPreview=12021-02-12T16:00:00+00:003659.24UK Fluids NetworkCOVID-19 has presented us with the most difficult healthcare and societal challenge we have faced in living memory. To understand the mechanisms of transmission we have had to rapidly collect new evidence on the SARS-CoV-2 virus ranging from laboratory data on survival and fluid dynamics studies on droplet dispersion through to epidemiological evidence from outbreaks, contract tracing and cohort studies. Over this time we have become acutely aware of the role that the environment plays in transmission, and how our interactions in indoor spaces determine the risk of infection. But this is not the first disease to be associated with the built environment. Many other respiratory diseases have a clear association with indoor spaces including tuberculosis and influenza. Pathogens such as pseudomonas, legionella are associated with water systems, and even hospital acquired infections such as MRSA have been linked to dispersion within the environment. This presentation sets out what we know about transmission of pathogens in the built environment particular focus on the complex interactions between engineering systems, fluid dynamics, microbiology and the behaviour of people that determine the dispersion, transport and survival of pathogens. Engineering and modelling approaches that can be used to understand mechanisms for transmission and implement mitigation strategies are discussed. The talk discusses how research findings may be used to support practice, and where there gaps in knowledge in both understanding of fundamental processes and the real performance of engineering solutions.https://cassyni-user-files-prod.s3.amazonaws.com/5s6px6T25UThnoBQnothB4 https://cassyni.com/events/CwTizKazA2f4Q92QVacuWM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/o9NEB4aumKt5bg2YH4J8E https://cassyni.com/events/FQhkDjpcMKRYm5Vy3GXYEH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WHjv76feg99z5xZLrb4SKG https://cassyni.com/slides/outline/NKMs9s9fTKHS4RTgAMQWgV https://cassyni.com/events/NKMs9s9fTKHS4RTgAMQWgV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3cUcuHtHtRyBTm4mr1MBcA https://cassyni.com/events/NKMs9s9fTKHS4RTgAMQWgV?videoPreview=1 Internal flow in evaporating water drops: dominance of Marangoni flownohttps://cassyni.com/events/NKMs9s9fTKHS4RTgAMQWgV?videoPreview=12022-06-21T15:00:00+00:00936.52Experiments in FluidsThe internal flow field in evaporating sessile water drops is experimentally investigated in the present work. The interdependency in the prevailing thermal field and the internal flow field is analyzed by simultaneous utilization of infrared thermography and particle image velocimetry. Experiments are conducted on a hydrophobic substrate while varying the substrate temperature between 25 and 60 ∘C, resulting in a significant variation in the strength of internal convection. For the case of a non-heated substrate, a monotonic variation in temperature along the liquid–vapor interface results in an axisymmetric flow field inside the drop. For heated substrates, the presence of a cold spot at the liquid–vapor interface due to the dominance of the Marangoni flow results in a non-axisymmetric flow field. In such a situation, two counter-rotating vortices inside the drop are visualized. Here, the velocities inside the drop are ∼ O(mm/s), where velocities of ∼ O(μm/s) are previously reported for buoyancy-dominated flows. Qualitative features in the internal flow field, such as the duration of the presence of the non-axisymmetric flow and the shift in the center of vortices, highlight more vigorous Marangoni convection in drops evaporating on substrates maintained at a higher temperature. Quantitative analysis of the flow field is presented in terms of the spatiotemporal evolution of velocity and vorticity inside the drop, which are further correlated to the evolution of the thermal field by analyzing the interfacial temperature difference. Further, by observing the deposition pattern of tracer particles formed after the evaporation of drops, the effect of variations in the internal flow field on deposition patterns is deduced.https://cassyni-user-files-prod.s3.amazonaws.com/3cUcuHtHtRyBTm4mr1MBcA https://cassyni.com/slides/outline/HNsph2gR4jkQfKkL9shWxM https://cassyni.com/events/HNsph2gR4jkQfKkL9shWxM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AA4smMCzhkJthq61qJ2irA https://cassyni.com/events/HNsph2gR4jkQfKkL9shWxM?videoPreview=1 A Scalable Adaptive-Matrix SpMV for Heterogeneous Architecturesnohttps://cassyni.com/events/HNsph2gR4jkQfKkL9shWxM?videoPreview=12022-09-14T14:30:00+00:001946.52NEKTAR++No abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/AA4smMCzhkJthq61qJ2irA https://cassyni.com/slides/outline/Vj5vr7rY3BbGYzz98EGF6V https://cassyni.com/events/Vj5vr7rY3BbGYzz98EGF6V/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TMZ3CTYohrzgKDU1N2nJiz https://cassyni.com/events/Vj5vr7rY3BbGYzz98EGF6V?videoPreview=1 Taking stock: Cellular agriculture in sustainable food systemsnohttps://cassyni.com/events/Vj5vr7rY3BbGYzz98EGF6V?videoPreview=12022-10-25T15:30:00+00:003543.0Springer Nature Sustainable Development Goals ProgrammeThere are many viewpoints on how cellular agriculture technologies can benefit or hinder sustainable food system transformations. Moderated by Annisa Chand, Senior Editor Nature Food, our panel of distinguished experts from our new focus issue consider cellular agriculture from perspectives of sustainable food systems. The webinar will consider issues of environmental sustainability, food justice, corporate power, potential for greenwashing, virtue ethics, scaling for impact, and will examine the tensions and opportunities for the field in contemporary food systems dialogue. Nature Food publishes commentary and research on food production, processing, distribution and consumption that relates to food security and sustainable food systems. Launched in January 2020, it is a transformative journal from the Nature Research Portfolio. To learn more about Nature Food, please visit the journal at [nature.com/natfood](https://www.nature.com/natfood). https://cassyni-user-files-prod.s3.amazonaws.com/TMZ3CTYohrzgKDU1N2nJiz https://cassyni.com/slides/outline/2ZRhJXGfu18nMPTd9DsnQd https://cassyni.com/events/2ZRhJXGfu18nMPTd9DsnQd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TeArXAacRrm1vQWbkVuzkW https://cassyni.com/events/2ZRhJXGfu18nMPTd9DsnQd?videoPreview=1 Topological Origin of Certain Fluid and Plasma Wavesnohttps://cassyni.com/events/2ZRhJXGfu18nMPTd9DsnQd?videoPreview=12021-10-01T15:00:00+00:003625.4Journal of Fluid MechanicsSymmetries and topology play central roles in our understanding of physical systems. Topology, for instance, explains the precise quantization of the Hall effect and the protection of surface states in topological insulators against scattering from disorder or bumps. However discrete symmetries and topology have so far played little role in thinking about the fluid dynamics of oceans and atmospheres. In this talk I show that, as a consequence of the rotation of the Earth that breaks time reversal symmetry, equatorially trapped Kelvin and Yanai waves emerge as topologically protected edge modes. The non-trivial structure of the bulk Poincaré waves encoded through the first Chern number of value 2 guarantees the existence of these waves. Thus the oceans and atmosphere of Earth naturally share basic physics with topological insulators. As equatorially trapped Kelvin waves in the Pacific ocean are an important component of El Niño Southern Oscillation and other climate oscillations, these new results demonstrate that topology plays a surprising role in Earth’s climate system. We also predict that waves of topological origin will arise in magnetized plasmas. A planned experiment at UCLA’s Basic Plasma Science Facility to look for the waves is described.https://cassyni-user-files-prod.s3.amazonaws.com/TeArXAacRrm1vQWbkVuzkW https://cassyni.com/slides/outline/345JMCvCLTgqM9zWjfAafw https://cassyni.com/events/345JMCvCLTgqM9zWjfAafw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/ND3D1eTqbpfcnzvojsg6o8 https://cassyni.com/events/345JMCvCLTgqM9zWjfAafw?videoPreview=1 Harnessing viscous streaming in complex active systems: mini-bots in fluids.nohttps://cassyni.com/events/345JMCvCLTgqM9zWjfAafw?videoPreview=12021-02-26T16:00:00+00:003474.96Journal of Fluid MechanicsViscous streaming is a phenomenon where an oscillating body generates stable, predictable and robust fluid flows that can be used to manipulate the body’s local surroundings. Viscous streaming has been well explored and characterized theoretically, experimentally and computationally for simple shapes such as cylinders and spheres, and leveraged in microfluidics for transport, mixing, particle separation and assembly. However, little is known beyond simple geometries, in particular when multiple curvatures are involved. Here we explore the effects of body geometric variations on topological flow responses, and connect them with potential uses in micro-robotics.https://cassyni-user-files-prod.s3.amazonaws.com/ND3D1eTqbpfcnzvojsg6o8 https://cassyni.com/slides/outline/DRgzKZWDZ5KFsfHekm7UMT https://cassyni.com/events/DRgzKZWDZ5KFsfHekm7UMT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XrGmDCk7eXHcVaT3ovozpv https://cassyni.com/events/DRgzKZWDZ5KFsfHekm7UMT?videoPreview=1 Topological photonics in disordered atomic latticesnohttps://cassyni.com/events/DRgzKZWDZ5KFsfHekm7UMT?videoPreview=12022-07-04T15:50:00+00:001157.08ETOPIMA honeycomb lattice of atoms coupled by light exhibits topological bandgaps and protected edge modes when subjected to an external magnetic field, even when atomic positions are partially randomized. Moreover, disorder in atomic positions can be at the origin of topological properties. Finally, topological nature of a bandgap influences on the localization length of spatially localized modes that arise inside the bandgap due to disorder.https://cassyni-user-files-prod.s3.amazonaws.com/XrGmDCk7eXHcVaT3ovozpv https://cassyni.com/slides/outline/9y9kzmyYUsScqxz676jWpd https://cassyni.com/events/9y9kzmyYUsScqxz676jWpd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7Mh2PrT27tPH7P4KxSbNia https://cassyni.com/slides/outline/CSPnECDAgAD7CuTeene9YZ https://cassyni.com/events/CSPnECDAgAD7CuTeene9YZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2uGWaUogiBxBe6DvjdSbPt https://cassyni.com/slides/outline/PJghMrxbjbKJsez5YtpH81 https://cassyni.com/events/PJghMrxbjbKJsez5YtpH81/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PZpctXVXoqBqiVj9E12pWi https://cassyni.com/events/PJghMrxbjbKJsez5YtpH81?videoPreview=1 Steering microscopic particles in viscous flows via shape and deformabilitynohttps://cassyni.com/events/PJghMrxbjbKJsez5YtpH81?videoPreview=12020-10-23T15:00:00+00:003814.04Journal of Fluid MechanicsUnderstanding and controlling the transport of microscopic particles in viscous flows stems from the fundamental question of fluid-structure interactions but has also important implications for separation processes or bacterial contamination. Using recent microfabrication techniques, we produce a variety of microscopic particles and control precisely their shape and material properties. Investigating the transport dynamics of these particles in representative microfluidic flows we demonstrate how shape, mechanical properties or even activity govern particle trajectories. Combining our experimental findings with numerical and theoretical modeling performed by our collaborators we elucidate in detail the role of particle symmetry, chirality or deformability.https://cassyni-user-files-prod.s3.amazonaws.com/PZpctXVXoqBqiVj9E12pWi https://cassyni.com/slides/outline/Kr9U35RvfPSfqxgWuESKbB https://cassyni.com/events/Kr9U35RvfPSfqxgWuESKbB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/V3sEnVhpVWUazPrqQ1L8u4 https://cassyni.com/events/Kr9U35RvfPSfqxgWuESKbB?videoPreview=1 Dilation Theory, a one-century-old storynohttps://cassyni.com/events/Kr9U35RvfPSfqxgWuESKbB?videoPreview=12022-05-05T16:10:00+00:003184.04Acta Scientiarum MathematicarumThis is a friendly recount of dilation theory in the complex plane. Starting with the pioneering result of F. Riesz (1923) in the Hardy space $H^p$, we provide a wide range of theorems which are uniformly spread over a century to tackle the problems in different function spaces such as the Bergman space, super-harmonically weighted Dirichlet spaces, the Bloch space, model spaces, de Branges-Rovnyak spaces, etc. We finish with some recent results and open questions, emerged in the last decade, to highlight the need for novel tools in dealing with such problems.https://cassyni-user-files-prod.s3.amazonaws.com/V3sEnVhpVWUazPrqQ1L8u4 https://cassyni.com/slides/outline/WiQm47fUKTd9NEWYWmg1Y1 https://cassyni.com/events/WiQm47fUKTd9NEWYWmg1Y1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Uqas8pcY6DqZGgh8rrRuPc https://cassyni.com/events/WiQm47fUKTd9NEWYWmg1Y1?videoPreview=1 Swimming clubs instead of committees as a road to well-being: A critical provocation to HE futuresnohttps://cassyni.com/events/WiQm47fUKTd9NEWYWmg1Y1?videoPreview=12022-12-13T22:00:00+00:003345.52School of ManagementIn the context of the increased frustration and anxiety around managerialism of universities, this talk explores how a group of 52 academics, from six different universities, diverse disciplines and levels are responding collectively outside of their work. Moreover, it tracks the enactment of five ‘Slow Swimming Clubs’ across Europe, set up by the author. The clubs represent a particular form of leisure crafting, called slow swimming. Using an auto-ethnographic approach, the impact of these Slow Swimming Clubs are explored over a 13 year period. The presentation reflects on the initial impact of this practice, around an individualised compensatory respite from the academics’ feelings of frustration and insecurity. This respite was framed in terms of temporal and aesthetic task crafting. The presentation then reflects on how the external, counter-performative nature of leisure crafting has opened up time and space for job crafting, back in their universities. The differentiating feature of this research is around the role of academic agency in moving beyond respite towards structural contestation and more systemic change. It also highlights the importance of the relationship between leisure and work within this crafting process. Through placing the aesthetic and temporal dimensions in the foreground, the article offers a significant conceptual contribution to crafting typology. It also extends slow scholarship, by advocating an embodied, sensual and experiential response to the fast pedagogies of managerialism. Most crucially here, the talk will explore the contribution of the Slow Swimming Club form of leisure crafting to HE and management futures, around well-being, space and time. https://cassyni-user-files-prod.s3.amazonaws.com/Uqas8pcY6DqZGgh8rrRuPc https://cassyni.com/slides/outline/RHH7YbYhVRY4yNGJurgDYZ https://cassyni.com/events/RHH7YbYhVRY4yNGJurgDYZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7DtEpyUiHUyyPWjyC399Av https://cassyni.com/events/RHH7YbYhVRY4yNGJurgDYZ?videoPreview=1 Finding the halo: a separated vortex ring underlies the flight of the dandelionnohttps://cassyni.com/events/RHH7YbYhVRY4yNGJurgDYZ?videoPreview=12019-11-01T13:00:00+00:003110.48UK Fluids NetworkIn this talk I will provide a brief overview of the research on applied fluid dynamics and vortex-dominated flow in my research group, and I will present in-depth our recent findings on the flight of the dandelion fruit (https://doi.org/10.1038/s41586-018-0604-2). The dandelion uses a bundle of bristles, known as the pappus, to enhance the drag and to slow down its descent. This passive flight mechanism allows the dandelion to be carried by the wind for even hundreds of miles. The underlying fluid dynamics of this drag-enhancing mechanism was, however, unknown. We found that when the dandelion falls, the air flows through the pappus and forms a bubble of recirculating flow. This bubble, which we named the separated vortex ring (SVR), sits stably a few millimetres above the dandelion, like a halo. In this talk I will describe how we discovered this extraordinary new type of vortex, and what we have learnt of it. The discovery of the SVR suggests the existence in nature of a new type of locomotion. We envisage that this discovery might contribute to explain the function of many hairy structures in the plant and animal kingdoms. We also envisage that it may contribute to the design of micro aerial vehicles that will be passively carried by the wind. The research on the dandelion fruit is a collaboration with the research groups of Dr Naomi Nakayama (School of Biological Sciences) and Dr Enrico Mastropaolo (School of Engineering) at the University of Edinburgh.https://cassyni-user-files-prod.s3.amazonaws.com/7DtEpyUiHUyyPWjyC399Av https://cassyni.com/slides/outline/61zYjwKENZwCCnDozZ5urM https://cassyni.com/events/61zYjwKENZwCCnDozZ5urM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UBUqfH8HPfASEiC9KJsTFk https://cassyni.com/events/61zYjwKENZwCCnDozZ5urM?videoPreview=1 High-dimensional, multiscale online changepoint detectionnohttps://cassyni.com/events/61zYjwKENZwCCnDozZ5urM?videoPreview=12021-05-13T16:00:00+00:002261.6DataSıgWe introduce a new method for high-dimensional, online changepoint detection in settings where a p-variate Gaussian data stream may undergo a change in mean. The procedure works by performing likelihood ratio tests against simple alternatives of different scales in each coordinate, and then aggregating test statistics across scales and coordinates. The algorithm is online in the sense that both its storage requirements and worst-case computational complexity per new observation are independent of the number of previous observations. We prove that the patience, or average run length under the null, of our procedure is at least at the desired nominal level, and provide guarantees on its response delay under the alternative that depend on the sparsity of the vector of mean change. Simulations confirm the practical effectiveness of our proposal, which is implemented in the R package 'ocd', and we also demonstrate its utility on a seismology data set.https://cassyni-user-files-prod.s3.amazonaws.com/UBUqfH8HPfASEiC9KJsTFk https://cassyni.com/slides/outline/15WWH6qyyzQAogWTz5Nv8D https://cassyni.com/events/15WWH6qyyzQAogWTz5Nv8D/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5p6HQvoaJ8TDxHvbNqeSKY https://cassyni.com/events/15WWH6qyyzQAogWTz5Nv8D?videoPreview=1 A signal processing perspective of acoustically-excited jet shear layersnohttps://cassyni.com/events/15WWH6qyyzQAogWTz5Nv8D?videoPreview=12023-02-01T16:00:00+00:001980.84Department of AeronauticsAn alternative perspective of the behaviour of jet shear layers in response to acoustic excitation is developed using concepts in signal processing. A central idea is that the vortices that roll-up in the shear layer are similar to the discrete samples of a digital control system. This analogy has the interesting corollary that the Nyquist-Shannon sampling theorem should apply. It has also been understood since the 1990s that shear layers act as demodulators when subjected to amplitude-modulated perturbations – some distance downstream of the source of excitation, only perturbations at the modulating frequency persist (at baseband). It is possible to explain this behaviour through the lens of signal processing by describing the relationship between the shear layer vorticity signal and the excitation waveform as a rectifier, along with the sampling action already described. The rectifier + sampler model offers insights into shear layer behaviour that are not perceptible using the tools of fluid mechanics alone. The model is verified through a series of experiments on both free and attached jets. The implications of the analogy are explored, one of which is the advent of an excitation technique where the amplitude modulation signal driving the acoustic source is overmodulated. This overmodulation technique has application in flow control, and results in a doubling of the response frequency and hence the input bandwidth. This talk is based on two recently published journal papers. https://cassyni-user-files-prod.s3.amazonaws.com/5p6HQvoaJ8TDxHvbNqeSKY https://cassyni.com/slides/outline/3YkXWX5cBHAfAcz2XmHYr9 https://cassyni.com/events/3YkXWX5cBHAfAcz2XmHYr9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FDjtfQLaSFwXBmYvKxxUWz https://cassyni.com/events/3YkXWX5cBHAfAcz2XmHYr9?videoPreview=1 Putting Accounting and Finance on the Same Platformnohttps://cassyni.com/events/3YkXWX5cBHAfAcz2XmHYr9?videoPreview=12023-03-15T01:00:00+00:004498.76SACLA two-factor model explains returns for a variety of test portfolios, including those based of CAPM beta and factor portfolios in extant pricing models. The two-factor model involves the market factor and a factor based on firms’ accounting fundamentals that has the feature of providing a hedge in down markets and a reverse-hedge in up markets. For a wide range of test portfolios, returns are described by sensitivity to the market factor with a beta of one and exposure to the hedging factor, and with zero alpha. Thus the paper provides a two-factor representation of the intertemporal asset pricing model (ICAPM) that serves the needs of the intertemporal investor. Paper: click [here](https://web.tresorit.com/l/QB9Ua#zgaAVuYthTVP7uWNCduhWw)https://cassyni-user-files-prod.s3.amazonaws.com/FDjtfQLaSFwXBmYvKxxUWz https://cassyni.com/events/ATpzA68xKgvSfRybuCrUzq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6vYtmU1WHQhVPjbpSQCMKt https://cassyni.com/events/8Vxkwiwu3EnaN8ooy1Q2zR/seminar/qa https://cassyni.com/slides/outline/8Vxkwiwu3EnaN8ooy1Q2zR https://cassyni.com/events/8Vxkwiwu3EnaN8ooy1Q2zR/abstract https://cassyni-user-files-prod.s3.amazonaws.com/ARQMUb8duuG8M6FmGMveGW https://cassyni.com/events/8Vxkwiwu3EnaN8ooy1Q2zR?videoPreview=1 Architected and biobased metamaterials: integration of shape adaptation, structural functionality and sustainabilitynohttps://cassyni.com/events/8Vxkwiwu3EnaN8ooy1Q2zR?videoPreview=12024-11-26T14:00:00+00:004066.04MetaMATIn the last 30 years, mechanical metamaterials have emerged for energy absorption, vibroacoustics, and shape morphing, utilizing unique deformation mechanisms like negative Poisson's ratio and stiffness. While traditional designs often use lattice structures, innovative topologies, including Kirigami and multiscale composites, are being explored. Sustainability is now a key focus, addressing challenges in disassembly and recyclability of complex multi-material configurations. This presentation will cover efforts to integrate sustainable materials from natural plants and synthetic biology into mechanical metamaterials. We will discuss how Kirigami and fractal patterns enable large-scale recycling and unique deformation behaviours, as well as the use of natural fibres like flax and hemp in multifunctional composites for shape memory and soft robotics, and materials that actuate with water and hydrocarbons. Additionally, we will highlight advancements in auxetic foams to enhance energy absorption capabilities. https://cassyni-user-files-prod.s3.amazonaws.com/ARQMUb8duuG8M6FmGMveGW https://cassyni.com/events/AUZB8TXzo51LTr63KyFyQy/seminar/qa https://cassyni.com/slides/outline/AUZB8TXzo51LTr63KyFyQy https://cassyni.com/events/AUZB8TXzo51LTr63KyFyQy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LgSeB7yjj3Ey3BAsf6cLG6 https://cassyni.com/events/AUZB8TXzo51LTr63KyFyQy?videoPreview=1 Celebrating Editorial Impact (2024)nohttps://cassyni.com/events/AUZB8TXzo51LTr63KyFyQy?videoPreview=12024-12-11T15:00:00+00:003621.64Topics at the heart of our communityWith this special end-of-year event, we showcase a wide range of achievements by Springer Nature Editors who have gone above and beyond over the past year, and had a meaningful impact on both their journals and the wider editorial community. This year we are introducing new categories for recognizing editorial excellence: Content Innovation, Research Integrity, Journal Development, Publishing for Progress, and Career Insightshttps://cassyni-user-files-prod.s3.amazonaws.com/LgSeB7yjj3Ey3BAsf6cLG6 https://cassyni.com/events/LMYtAkzNyb1PU9NK5wa7Qh/seminar/qa https://cassyni.com/slides/outline/LMYtAkzNyb1PU9NK5wa7Qh https://cassyni.com/events/LMYtAkzNyb1PU9NK5wa7Qh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/MBSz7uxkDe5617BKfzstfx https://cassyni.com/events/LMYtAkzNyb1PU9NK5wa7Qh?videoPreview=1 Nature Water Talks: Towards net zero in the wastewater sectornohttps://cassyni.com/events/LMYtAkzNyb1PU9NK5wa7Qh?videoPreview=12024-11-06T15:00:00+00:003520.84Springer Nature Sustainable Development Goals ProgrammeWastewater treatment is responsible for large amount of greenhouse gases emissions, especially methane and nitrous oxide. Accounting for all those emissions is complex because emissions originate from several parts of the process, but it is the first, essential step towards a more sustainable wastewater industry. In this webinar we’ll talk to Maria Salvetti (Florence School of regulation) and Zhiyong Jason Ren (Princeton University) about the route to achieve energy neutrality and eventually zero GHGs emissions in the wastewater sector. https://cassyni-user-files-prod.s3.amazonaws.com/MBSz7uxkDe5617BKfzstfx https://cassyni.com/events/723ZvJXD8E3xpjSVmhWVwB/seminar/qa https://cassyni.com/slides/outline/723ZvJXD8E3xpjSVmhWVwB https://cassyni.com/events/723ZvJXD8E3xpjSVmhWVwB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/M4Hark3s7Gw4arrYYcam34 https://cassyni.com/events/723ZvJXD8E3xpjSVmhWVwB?videoPreview=1 Gender Equality in Times of War: Addressing Violence, Justice, and Displacementnohttps://cassyni.com/events/723ZvJXD8E3xpjSVmhWVwB?videoPreview=12024-11-25T15:00:00+00:003680.04Springer Nature Sustainable Development Goals ProgrammeDespite global efforts, true gender equality remains an unachieved goal. According to the United Nations, Sustainable Development Goal 5, “Achieve gender equality and empower all women and girls,” is not going to be met by 2030, and war only intensifies these disparities. In this webinar, three experts will discuss the specific ways women are affected by conflict and global policies that can be used to support them and enable their agency as they struggle with issues such as gender-based violence, access to justice, and forced displacement. Their presentations will provide a nuanced view of the often-overlooked effects of war on women, with attention to both immediate and long-term impacts. The session will also include time for audience questions, allowing for engagement with these timely and pressing issues. This webinar is an opportunity to deepen understanding of the challenges facing gender equality in conflict contexts, offering insights into why these issues demand serious consideration in today’s global landscape.https://cassyni-user-files-prod.s3.amazonaws.com/M4Hark3s7Gw4arrYYcam34 https://cassyni.com/slides/outline/BTt1LTLw5M3DHPCHgMH55f https://cassyni.com/events/BTt1LTLw5M3DHPCHgMH55f/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LyLhk6KpR4ko5KMGH8sj8a https://cassyni.com/events/BTt1LTLw5M3DHPCHgMH55f?videoPreview=1 Landfill Methane Emission: A Case Study using Inversion Methods, Satellites and Cavity Ring Down Spectroscopynohttps://cassyni.com/events/BTt1LTLw5M3DHPCHgMH55f?videoPreview=12025-03-21T12:00:00+00:001901.32Frontiers in Earth ScienceLandfill Methane Emission: A Case Study using Inversion Methods, Satellites and Cavity Ring Down Spectroscopy This study uses in situ measurements, satellite data, and modeling techniques toinvestigate methane (CH4) emissions from the Caieiras landfill in Sao Paulo, Brazil. Methane is the second most significant greenhouse gas due to its high heatingpotential. Previous studies have shown that landfills can be considered the super-emitters of methane. Quantifying its emissions is essential to comprehending the emissions patterns of this emitter, promoting an improvement in data from inventories. Multiple platforms were used to obtain the data and better characterize the landfill.Satellite data from TROPOMI and EMIT were analyzed during the present study to characterize emission feathers. The results showed consistent emissions over four years, as shown by the inversions obtained using TROPOMI data. EMIT could identify one plume originating in the landfill dispersed over the city’s populated area. The in situ data were acquired near the Caieiras landfill using a greenhouse gas analyzer with integrated off-axis cavity output spectroscopy (OA-ICOS), a high-precision method to measure gases in the atmosphere. Three campaigns were conducted in 2023 on February 14, July 6, and November 22. The results obtained in all three campaigns showed median concentration values above 2 ppm, reaching values close to 35 ppm. These data were integrated into the AERMOD dispersion model, combined with meteorological data, and estimated methane emission rates, revealing variability of concentrations, where emission rates were 12,974.4 kg/h, 11,284.92 kg/h and 23,472mkg/h, respectively, for three days of sampling. The integrated approach in this study promotes valuable insights into landfill emissions and emphasizes targeted strategies for mitigating greenhouse gases. Results support the elaboration of policies to enhance waste management and reduce the climate impact produced by waste. Keywords: Methane, Landfills, Greenhouse Gas Analyzer, Inverse Modelling,https://cassyni-user-files-prod.s3.amazonaws.com/LyLhk6KpR4ko5KMGH8sj8a https://cassyni.com/slides/outline/Dw82ZsaZGdokKYS5995S5s https://cassyni.com/events/Dw82ZsaZGdokKYS5995S5s/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QrJ1Sg2rRKegTybHFKCdga https://cassyni.com/events/Dw82ZsaZGdokKYS5995S5s?videoPreview=1 Optimal Structural Metamaterials for Launch Vibration Controlnohttps://cassyni.com/events/Dw82ZsaZGdokKYS5995S5s?videoPreview=12024-11-27T14:00:00+00:003170.44Department of Aeronautics and AstronauticsBy controlling and optimally grading properties at the microscale, structural metamaterials can exhibit exciting and unexpected emergent behaviour with applications across numerous fields of engineering. Using the numerical framework and optimization methodologies developed within our group, which will be elaborated in the talk, we have synthesized optimal metamaterials for compliance, morphing, thermo-structural response and many other fields. In this talk we will specifically consider the application of metamaterials to vibration control and mitigation for spacecraft structures during launch. By demonstrating the complete design process from optimization to reconstruction to experimental validation it will be shown that the process is effective and offers a new approach for the design of spacecraft components.https://cassyni-user-files-prod.s3.amazonaws.com/QrJ1Sg2rRKegTybHFKCdga https://cassyni.com/events/Jsdh9LZh4aGmvSR9vo5F8H/seminar/qa https://cassyni.com/slides/outline/Jsdh9LZh4aGmvSR9vo5F8H https://cassyni.com/events/Jsdh9LZh4aGmvSR9vo5F8H/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PBDwu6svx1vv6cZnZhF6ut https://cassyni.com/events/Jsdh9LZh4aGmvSR9vo5F8H?videoPreview=1 Carbon fiber based structural battery compositesnohttps://cassyni.com/events/Jsdh9LZh4aGmvSR9vo5F8H?videoPreview=12025-01-30T15:00:00+00:003537.0Department of AeronauticsStructural battery composites are made from carbon fibre reinforced polymer composite electrodes. The negative electrode consists of carbon fibres in a ultra-thin spread tow. The positive electrode consists of lithium iron phosphate (LFP) coated onto carbon fibres in a spread tow [1,2]. An electrically insulating, ionically conductive, separator is sandwiched between the electrodes. The stacked layers are impregnated by a bi-phasic structural electrolyte providing mechanical load transfer between fibres and plies as well as Li-ion migration between the electrodes. This presentation will give an overview of recent progress in carbon fibre based structural battery composites. In particular, the coupled electro-chemo-mechanical processes and their effect on the composite material and its constituents will be discussed. During electrochemical cycling, the elastic properties of the electrode materials, i.e., carbon fiber and lithium iron phosphate, swells/shrinks and undergoes changes in elastic moduli [3]. These changes to the composite’s constituents give rise to high internal stresses that may cause damage to the structural battery electrolyte or the fibres and thereby affect the multifunctional performance of the structural battery composite [4]. The presentation will also discuss research needs for improved multifunctional performance of structural battery composites. References [1] Chaudhary R., et al. Structural Positive Electrodes Engineered for Multifunctionality. Advanced Science, 2024, 24014012. [2] Chaudhary R., et al. Unveiling the Multifunctional Carbon Fibre Structural Battery, Advanced Materials, 2024, 2409725. [2] Duan S., et al. Effect of lithiation on the elastic moduli of carbon fibres, Carbon. 185: 234-241, 2021. [3] Larsson C., et al. Effects of lithium insertion induced swelling of a structural battery negative electrode. Compos. Sci. Technol. 244: 110299, 2023. https://cassyni-user-files-prod.s3.amazonaws.com/PBDwu6svx1vv6cZnZhF6ut https://cassyni.com/slides/outline/JNz66evAd7iivftGLMnSry https://cassyni.com/events/JNz66evAd7iivftGLMnSry/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GQjgv54Hyh3LsCt9tntuKL https://cassyni.com/events/JNz66evAd7iivftGLMnSry?videoPreview=1 What's next after net zero?nohttps://cassyni.com/events/JNz66evAd7iivftGLMnSry?videoPreview=12024-01-18T15:00:00+00:005339.84Frontiers in ScienceIn this Frontiers Forum Deep Dive session on 18 January 2024, Sofia Palazzo Corner, Prof Martin Siegert and Prof Joeri Rogelj discussed the amount of temperature change we can expect after CO₂ emissions from human activities reach net zero, and how this can be built into climate models. They were joined for a panel and question and answer session by Ben Sanderson, Charlie Koven and Tessa Khan. The session brought together the authors of the Frontiers in Science lead article ‘The Zero Emissions Commitment (ZEC) and climate stabilization’ in which they present the first comprehensive analysis of Earth processes controlling global temperatures and our knowledge gaps for each – plus a pioneering framework for building climate models that are better equipped to predict ZEC.https://cassyni-user-files-prod.s3.amazonaws.com/GQjgv54Hyh3LsCt9tntuKL https://cassyni.com/events/UFxB2KrfQGo3nBtHqvYozu/seminar/qa https://cassyni.com/slides/outline/UFxB2KrfQGo3nBtHqvYozu https://cassyni.com/events/UFxB2KrfQGo3nBtHqvYozu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6odDoRGcdsUaGtRR4UYGvS https://cassyni.com/events/7Wio5cgcy3XneCS1ZodU7P/seminar/qa https://cassyni.com/slides/outline/7Wio5cgcy3XneCS1ZodU7P https://cassyni.com/events/7Wio5cgcy3XneCS1ZodU7P/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QWDWTgvuNwAj1zJsbgJznJ https://cassyni.com/events/7Wio5cgcy3XneCS1ZodU7P?videoPreview=1 Our Approach to Integrity Investigationsnohttps://cassyni.com/events/7Wio5cgcy3XneCS1ZodU7P?videoPreview=12025-02-20T15:00:00+00:003705.04Topics at the heart of our communityHow can Springer Nature support Editors when concerns are raised about a paper or papers in your journal? Join Tim Kersjes, from the Springer Nature Research Integrity Group, alongside Jo Cox and Alice Henchley from our Legal and Communications teams, to hear more about how Springer Nature conducts investigations and the resources available to our Editors.https://cassyni-user-files-prod.s3.amazonaws.com/QWDWTgvuNwAj1zJsbgJznJ https://cassyni.com/events/44BZkq9wtqf9cW8Sv9FWaZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Lb6fmcWqGoqsqnjHHBTZie https://cassyni.com/slides/outline/EvSrmsPVYuqd8mxUXgVCXP https://cassyni.com/events/EvSrmsPVYuqd8mxUXgVCXP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LeTXCwV5B4Qy8Pjz2Rfdhp https://cassyni.com/events/EvSrmsPVYuqd8mxUXgVCXP?videoPreview=1 Mode Sensitivity for Fluid Flows via Lagrangian Coherent Structuresnohttps://cassyni.com/events/EvSrmsPVYuqd8mxUXgVCXP?videoPreview=12024-10-29T14:00:00+00:00977.4Brunton LabThis research abstract describes how to use mode sensitivity to extract interpretable patterns from data-driven modal decomposition techniques.https://cassyni-user-files-prod.s3.amazonaws.com/LeTXCwV5B4Qy8Pjz2Rfdhp https://cassyni.com/events/Sn2yzuRyVG4SEUw8gn3wiV/seminar/qa https://cassyni.com/slides/outline/Sn2yzuRyVG4SEUw8gn3wiV https://cassyni.com/events/Sn2yzuRyVG4SEUw8gn3wiV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XShzfFNxmE9T7SEK4JJdkz https://cassyni.com/events/Sn2yzuRyVG4SEUw8gn3wiV?videoPreview=1 Inferential Machine Learning: Towards Human-collaborative Foundation Modelsnohttps://cassyni.com/events/Sn2yzuRyVG4SEUw8gn3wiV?videoPreview=12025-03-13T14:00:00+00:003485.04Research Seminars by Springer NatureNeural network driven applications like ChatGPT suffer from hallucinations where they confidently provide inaccurate information. A funda- mental reason for this inaccuracy is the feed-forward nature of inductive decisions taken by neural networks. Such decisions are a result of training schemes that do not allow networks to deviate from and creatively abduce reasons at inference. With the advent of foundation models that are adapted across applications and data, humans can directly intervene and prompt vision-language foundation models. However, without understanding the operational limits of the underlying networks, human interventions often lead to unfair, inaccurate, hallucinated and unintelligible outputs. These outputs undermine the trust in foundation models, thereby causing roadblocks to their adoption in everyday lives. In this talk, we review systematic ways to analyze and understand human interventions in neural network functionality at inference. Specifically, we show that a human-AI collaborative environment via inferential machine learning techniques is a promising endeavor. We coined the term inferential machine learning in 2022 to reflect the opportunities and challenges in this space. https://cassyni-user-files-prod.s3.amazonaws.com/XShzfFNxmE9T7SEK4JJdkz https://cassyni.com/events/Cwt4hmKHCSYxbJURn6hXyf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FHA3dtppxVpskGEkEtbHGS https://cassyni.com/events/FR85wBYuPjKSxEwzKncAhb/seminar/qa https://cassyni.com/slides/outline/FR85wBYuPjKSxEwzKncAhb https://cassyni.com/events/FR85wBYuPjKSxEwzKncAhb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5S2WGhBrYukg1SC2en5j7C https://cassyni.com/events/FR85wBYuPjKSxEwzKncAhb?videoPreview=1 Socioeconomic benefits of the Brazilian INSS AtestMed programmenohttps://cassyni.com/events/FR85wBYuPjKSxEwzKncAhb?videoPreview=12025-03-14T12:00:00+00:003070.2Risk Sciences#### Practice Insights: Renata Gomes Alcoforado ***[Risk Sciences](https://www.keaipublishing.com/en/journals/risk-sciences/)*** aims to foster diverse, multidisciplinary insights in risk sciences, bridging theory and practice through a series of academic activities. This talk is part of the "Practice Insights" track of this series, highlights key lessons from real-world experiences, offering valuable perspectives to researchers and practitioners alike. This study analyses forecast modelling with time series for INSS expenses related to the AtestMed programme within the Brazilian Welfare and Pension System. The AtestMed programme, a recent socioeconomic initiative by the Brazilian government, aims to manage benefit compensations due to temporary disability more efficiently. It is designed to improve and shorten delays in the processing and payment of compensations, leading to significant savings by reducing disability periods. The dataset used includes monthly monetary data from January 2021 to September 2024, adjusted for inflation according to the National Consumer Price Index (INPC). We examine the behaviour of INSS costs with and without the AtestMed programme, noting that it was implemented in July 2023. The methodology employs six different time series models (Simple, Holt and Holt-Winters Exponential Smoothing, ARMA, ARIMA and SARIMA) for analysing cost trends. By comparing the outcomes for total costs with and without AtestMed, this approach provides a deeper understanding of chronological as well as seasonal trends in INSS spending, anticipates variations, and optimises socioeconomic management. The forecasts generated from this study aim to enhance strategic decision-making within the scope of social security.https://cassyni-user-files-prod.s3.amazonaws.com/5S2WGhBrYukg1SC2en5j7C https://cassyni.com/events/Npsmk4mfNxZ1bJAraEQLkD/seminar/qa https://cassyni.com/slides/outline/Npsmk4mfNxZ1bJAraEQLkD https://cassyni.com/events/Npsmk4mfNxZ1bJAraEQLkD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/48EPWPpAqrZrPyxSbHP72W https://cassyni.com/events/Npsmk4mfNxZ1bJAraEQLkD?videoPreview=1 Critical Assessment of Quadratic Closures for Prediction of Corner Flow Separationnohttps://cassyni.com/events/Npsmk4mfNxZ1bJAraEQLkD?videoPreview=12025-11-18T16:00:00+00:003404.12AIAA JournalThe work proposed in this paper aims at improving the physical understanding and modelling of junction flows by conducting an analysis of several QCRs (Quadratic Constitutive Relations) applied to corner vortices. RANS computations are performed on two academic configurations for verification purposes and on a technical application of wing-body juncture featuring corner flows to achieve a better comprehension of the QCR variants ability to reproduce turbulent stress combinations relevant to secondary flows generation. This addresses the more theoretical interest of analysing the onset of corner separation (angle of attack 11 degree) and the role of corner flow vortices. Linear eddy viscosity model and the Extended QCR failed in detecting these vortical structures, the latter encountered numerical stability difficulties. On the other hand, QCR2000, QCR2020, QCR2024 showed a behaviour consistent with a simulation using Reynolds Stress Model, experiments and literature results. This better prediction was found to be related to the ability of these models to accurately detect the stress-induced vortex that delays and reduces the size of the corner separation. Notably, the more recent QCR2024 and QCR2020 have enhanced the estimation of the normal stress combination compared to the more widespread QCR2000, demonstrating their validity as alternative models.https://cassyni-user-files-prod.s3.amazonaws.com/48EPWPpAqrZrPyxSbHP72W https://cassyni.com/slides/outline/25cmgj5jYNNV52eQAZTr2q https://cassyni.com/events/25cmgj5jYNNV52eQAZTr2q/abstract https://cassyni-user-files-prod.s3.amazonaws.com/364xafEeX3SjeP8w18Tkh4 https://cassyni.com/events/25cmgj5jYNNV52eQAZTr2q?videoPreview=1 Numerical methods for computational evolving manifolds in industrial applicationsnohttps://cassyni.com/events/25cmgj5jYNNV52eQAZTr2q?videoPreview=12024-12-05T16:00:00+00:001715.48JKW Symposium TeamIn this talk, a cell-centered finite volume method is used to solve the G-equation on polyhedral meshes in three-dimensional space, that is, a general type of the level-set equation including advective, normal, and mean curvature flow motions. Numerical experiments quantitatively show that the size of time step proportional to an average size of computational cells is enough to obtain the second-order convergence in space and time for smooth solutions of the general level set equation. A qualitative comparison is presented for a nontrivial example to compare numerical results obtained with hexahedral and polyhedral meshes. Furthermore, we propose to use a nonlinear boundary condition when advective or normal flow equations in the level-set formulation are numerically solved on polyhedral meshes. Since a common choice of the initial condition in the level set method is a signed distance function, the eikonal equation on the boundary is compatibly correct at the starting point. Enforcing the eikonal equation on the boundary along time can effectively eliminate an inflow boundary condition which is typically necessary in the transport equation. For the chosen examples, the numerical results confirm that the eikonal boundary condition provides comparable accuracy and robustness in the evolution of the surface using the exact Dirichlet boundary condition. This project No. 2140/01/01 has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No. 945478.https://cassyni-user-files-prod.s3.amazonaws.com/364xafEeX3SjeP8w18Tkh4 https://cassyni.com/slides/outline/4Yrnv9KMjf8yRy7xiFNUkm https://cassyni.com/events/4Yrnv9KMjf8yRy7xiFNUkm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XDa1uZbfwuL8tqbjwT2wJe https://cassyni.com/events/4Yrnv9KMjf8yRy7xiFNUkm?videoPreview=1 A method to construct schemes that satisfy additional PDE constraints from any given good scheme: Application to entropy conservative schemes, kinetic energy preserving schemes and morenohttps://cassyni.com/events/4Yrnv9KMjf8yRy7xiFNUkm?videoPreview=12024-12-07T17:00:00+00:001903.24JKW Symposium TeamFor the general class of residual distribution (RD) schemes, including many finite element (such as continuous/discontinuous Galerkin) and flux reconstruction methods, an approach to construct entropy conservative/ dissipative semidiscretizations by adding suitable correction terms has been proposed by Abgrall (J.~Comp.~Phys. 372: pp. 640--666, 2018). This method can be seen as a alternative of SBP-SAT algorithms in that one does not try to achieve point-wise summation by part, but to do this at the level of elements. The advantage is that the algebra is much simpler, and the approach agnostic to the underlying PDE, as well as the structure of the mesh. This is done by introducing corrections that are compatible with local conservation and the algebraic constraints to fullfill. This is done by solving explicit local and small optimisation problems. This adapt to finite element type methods, including the discontinuous Galerkin ones, and many other. In this talk, I sketch how to realize this and provide some examples. A complete description can be found in https://arxiv.org/abs/1908.04556, and Abgrall, Oeffner Ranocha, J. Comput. Phys. 453, Article ID 110955, 24 p. (2022)., and Abgrall, Busto, Dumbser, Appl. Math. Comput. 440, Article ID 127629, 40 p. (2023). Image credit: [Ben Wicks (Unsplash)](https://unsplash.com/photos/a-cup-of-coffee-next-to-a-calculator-Uh6-JgCwbfM).https://cassyni-user-files-prod.s3.amazonaws.com/XDa1uZbfwuL8tqbjwT2wJe https://cassyni.com/events/BxarcQ2EKXSovYeRg8EDAm/seminar/qa https://cassyni.com/slides/outline/BxarcQ2EKXSovYeRg8EDAm https://cassyni.com/events/BxarcQ2EKXSovYeRg8EDAm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3fs4FK3bKCVTYnJgSkuQWa https://cassyni.com/events/BxarcQ2EKXSovYeRg8EDAm?videoPreview=1 Report from the field: Fieldwork in East Santo (Nkep)nohttps://cassyni.com/events/BxarcQ2EKXSovYeRg8EDAm?videoPreview=12025-05-02T01:10:00+00:003136.68Linguistics and Applied Language StudiesI'll give a short – and hopefully, dialogic – report on recently completed fieldwork in East Santo, Vanuatu. Expect a bit of linguistics, a bit of education stuff and some comments on kinship and returning photos of people's ancestors to the community 100 years later.https://cassyni-user-files-prod.s3.amazonaws.com/3fs4FK3bKCVTYnJgSkuQWa https://cassyni.com/slides/outline/NLEAhP88wVzxbXdxyo7YUu https://cassyni.com/events/NLEAhP88wVzxbXdxyo7YUu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5ZBuXs6jfGthRgWonANrk6 https://cassyni.com/events/NLEAhP88wVzxbXdxyo7YUu?videoPreview=1 Overview of Climate Risk Modeling in Insurancenohttps://cassyni.com/events/NLEAhP88wVzxbXdxyo7YUu?videoPreview=12025-01-16T03:00:00+00:001779.32Risk Sciences#### Research Insights: Kwangmin Jung ***[Risk Sciences](https://www.keaipublishing.com/en/journals/risk-sciences/)*** aims to foster diverse, multidisciplinary insights in risk sciences, bridging theory and practice through a series of academic activities. This talk is part of the "Research Insights" track of this series, presenting cutting-edge findings and methodologies, offering valuable perspectives to researchers and practitioners alike. Kwangmin Jung, Ph.D, is an Associate professor at the Department of Industrial and Management Engineering, Pohang University of Science and Technology (POSTECH) in South Korea. He received his doctoral degree in Finance (with a focus on risk management and insurance) at the University of St. Gallen, Switzerland. His research explores the intersection of actuarial science, risk management and insurance, particularly studying data science and information technology in insurance, emerging risk analysis (e.g., cyber risk, climate change risk) and extreme risk modeling.  This speech record is from Kwangmin's keynote speech for the [Risk Sciences Colloquium – International Seminar on Climate Risks](https://www.keaipublishing.com/en/journals/risk-sciences/event/risk-sciences-colloquium-international-seminar-on-climate-risks/), to be held on January 16, 2025, in Seoul, South Korea.https://cassyni-user-files-prod.s3.amazonaws.com/5ZBuXs6jfGthRgWonANrk6 https://cassyni.com/events/HPk8EYetYvTwCRvcyKQYkm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CL4zNCPTFiC93WtxRcUeHc https://cassyni.com/events/VjxEPdq1XNJo67ARwfyGtu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4PWisYEuasbk1CHV3sTrB8 https://cassyni.com/events/TGiDADbPL5YG3wveUtAuth/seminar/qa https://cassyni.com/slides/outline/TGiDADbPL5YG3wveUtAuth https://cassyni.com/events/TGiDADbPL5YG3wveUtAuth/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7rn2vCux9Q8Qg8NMKeRwdG https://cassyni.com/events/TGiDADbPL5YG3wveUtAuth?videoPreview=1 Computation of material property fields in multi-material systemsnohttps://cassyni.com/events/TGiDADbPL5YG3wveUtAuth?videoPreview=12025-05-13T13:00:00+00:003022.04MetaMATThis talk introduces a mathematical framework for determining material constants and stress components from strain measurements under given loading conditions. The problem is formulated using an energy functional approach, incorporating a Lagrange multiplier to ensure consistency between measured and computational strains. By enforcing the stationary point condition, the optimisation leads naturally to Euler–Lagrange equations. The presentation will discuss discretisation techniques for these equations and outline numerical solution strategies. To illustrate the effectiveness and practical relevance of the proposed approach, numerical examples and experimental benchmarks will be presented. The talk concludes with insights into ongoing research and a roadmap highlighting future developments and potential applications.https://cassyni-user-files-prod.s3.amazonaws.com/7rn2vCux9Q8Qg8NMKeRwdG https://cassyni.com/events/YDCFd44dif5HT3dzVMsucq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WZskKmXir8wJ3K2DNBDbHQ https://cassyni.com/events/KrZokXADhoLa388YBkWx4V/seminar/qa https://cassyni.com/slides/outline/KrZokXADhoLa388YBkWx4V https://cassyni.com/events/KrZokXADhoLa388YBkWx4V/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7pcuph4C3LvGVU5PPSmDre https://cassyni.com/events/KrZokXADhoLa388YBkWx4V?videoPreview=1 Revealing and Leveraging the Visual Information in Diffusion Modelsnohttps://cassyni.com/events/KrZokXADhoLa388YBkWx4V?videoPreview=12025-06-04T13:00:00+00:003771.04Journal on Image and Video ProcessingGenerating high-quality photo-realistic and creative visual content using diffusion models is a thriving area of research. In this talk, I will focus not on the generation process, but on understanding and leveraging the rich visual semantic information represented within diffusion models. Specifically, I will present our work that uses mechanistic interpretability tools such as k-sparse autoencoders (k-SAE) to probe various layers and denoising timesteps of different diffusion architectures. Next, I will present how to uncover monosemantic interpretable concepts pertaining to safety and photographic styles and steer the generation process thereby offering more controllability to users. https://cassyni-user-files-prod.s3.amazonaws.com/7pcuph4C3LvGVU5PPSmDre https://cassyni.com/events/WEBViskEvQxzZdRgCrTqk1/seminar/qa https://cassyni.com/slides/outline/WEBViskEvQxzZdRgCrTqk1 https://cassyni.com/events/WEBViskEvQxzZdRgCrTqk1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XrVTaiS1o5PNZzDkzLNGjg https://cassyni.com/events/WEBViskEvQxzZdRgCrTqk1?videoPreview=1 It’s time to assign nonforested, nonagricultural lands a global designationnohttps://cassyni.com/events/WEBViskEvQxzZdRgCrTqk1?videoPreview=12025-05-22T14:00:00+00:002042.0Cambridge PrismsEarth’s land cover consists of forests, agricultural land, urban settlements, and a large, heterogeneous category that includes deserts, grasslands, savannas, shrublands and tundra. This heterogeneous category has eluded a collective designation comparable to that of forests, which has contributed to its omission from multilateral programs and critical global initiatives. Potential designations for this land category—drylands, grasslands, grassy biomes, open ecosystems and rangelands—were evaluated for their relative advantages and disadvantages. Grassy biome is recommended as the most appropriate designation because it conveys a meaning that is distinct from forests, emphasizes that grasses often coexist with other plant growth forms. We respectfully urge multilateral organizations and partner nations to adopt ‘grassy biomes’ as a formal designation for this land category. The grassy biome designation would provide a more ecologically accurate distinction from forests than the one which is currently utilized.https://cassyni-user-files-prod.s3.amazonaws.com/XrVTaiS1o5PNZzDkzLNGjg https://cassyni.com/slides/outline/34wbtitfpeQMtGAoZ6scUM https://cassyni.com/events/34wbtitfpeQMtGAoZ6scUM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VUsaDsc7ctKdCzwVZGTY2A https://cassyni.com/events/34wbtitfpeQMtGAoZ6scUM?videoPreview=1 Research Funding and Impact: Are We Measuring What Matters?nohttps://cassyni.com/events/34wbtitfpeQMtGAoZ6scUM?videoPreview=12025-01-15T11:00:00+00:002787.44Academic Publishing in EuropeNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/VUsaDsc7ctKdCzwVZGTY2A https://cassyni.com/events/62QtTP3XQyq6PwfqH5AYKf/seminar/qa https://cassyni.com/slides/outline/62QtTP3XQyq6PwfqH5AYKf https://cassyni.com/events/62QtTP3XQyq6PwfqH5AYKf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WmCjb4bXb3DqowuecGymRp https://cassyni.com/events/62QtTP3XQyq6PwfqH5AYKf?videoPreview=1 Australia’s First Peoples: hunters of extinct megafauna or Australia’s first fossil collectorsnohttps://cassyni.com/events/62QtTP3XQyq6PwfqH5AYKf?videoPreview=12026-03-18T09:00:00+00:003304.36Royal Society PublishingClaims have been made about the presumed role of Australia’s First Peoples in the extinction of some of Australia’s megafauna. However, evidence used to suggest butchering may instead demonstrate fossil collection by Australia’s First Peoples. Using micro-computed tomography scanning and microscopic wear analysis, we analysed a cut sthenurine tibia from Mammoth Cave, Western Australia, previously interpreted as evidence of butchering. Our analyses suggest the cut occurred long after death and probably after fossilization. We investigated the possibility of long-distance transportation of a premolar of Zygomaturus trilobus gifted by First Peoples in the Kimberley region of Western Australia. This species is otherwise unknown from northern Australia but common in southern Australia. Using X-ray fluorescence, we tested the potential provenance of the premolar and found that it was elementally indistinguishable from Mammoth Cave premolars. These results suggest that First Peoples may have collected fossils in southern Australia before carrying them to the Kimberley region. A review of other recent claims of killing and/or butchering of extinct megafaunal species suggests they too may have been collected as fossils. We argue that fossils were valued, being collected and transported long distances by the First Peoples in Australia in all probability thousands of years before Europeans arrived on this continenthttps://cassyni-user-files-prod.s3.amazonaws.com/WmCjb4bXb3DqowuecGymRp https://cassyni.com/events/8VeugoH9cGbakt9Ppm5B3b/seminar/qa https://cassyni.com/slides/outline/8VeugoH9cGbakt9Ppm5B3b https://cassyni.com/events/8VeugoH9cGbakt9Ppm5B3b/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Ej2k7HnUpoET1Vu4kRTqjk https://cassyni.com/events/8VeugoH9cGbakt9Ppm5B3b?videoPreview=1 Targeting Cancer Stem Cells via ALDH1A Inhibition: Development of a New Class of Inhibitorsnohttps://cassyni.com/events/8VeugoH9cGbakt9Ppm5B3b?videoPreview=12025-06-20T10:15:00+00:002007.04Anti-Cancer Agents in Medicinal ChemistryThe Aldehyde Dehydrogenase 1A (ALDH1A) family has emerged as a compelling therapeutic target, particularly in oncology, due to its involvement in tumor progression, therapy resistance, and cancer stem cell (CSC) maintenance. Among these isoenzymes, ALDH1A1 has been identified as a CSC biomarker across multiple tumor types. Despite its potential, the clinical translation of ALDH1A1 inhibitors has been limited by poor isoform selectivity and off-target effects. In this work, we report the development of a novel class of selective ALDH1A1 inhibitors based on a dihydrobenzo[4,5]imidazo[2,1-c][1,2,4]triazine-3,4-dione (BITD) scaffold, identified through a core-repositioning strategy and rational design inspired by Isatin-based compounds. A focused library of derivatives was synthesized via a microwave-assisted protocol, and enzymatic profiling revealed promising selectivity for ALDH1A1 over other ALDH1A isoforms. In particular, compound 5 demonstrated potent inhibition of ALDH1A1 (86% inhibition when tested at 35 uM), with no measurable activity against ALDH1A2 or ALDH1A3. In silico modeling supported the experimental findings by revealing key molecular interactions underlying the observed selectivity. Collectively, these results provide a foundation for the development of isoform-selective ALDH1A1 inhibitors as innovative tools for targeting CSC populations in solid tumors. https://cassyni-user-files-prod.s3.amazonaws.com/Ej2k7HnUpoET1Vu4kRTqjk https://cassyni.com/events/AxtvvDWmoZNPrMxWnADujT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2JuSUmb4swisnwtPiNiuXk https://cassyni.com/events/Ht11gR61ML3uVeeVSAjHWm/seminar/qa https://cassyni.com/slides/outline/Ht11gR61ML3uVeeVSAjHWm https://cassyni.com/events/Ht11gR61ML3uVeeVSAjHWm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CUTicX3Uyjdp4gAttBA2wQ https://cassyni.com/events/Ht11gR61ML3uVeeVSAjHWm?videoPreview=1 The Rise of AI in the Publishing Landscapenohttps://cassyni.com/events/Ht11gR61ML3uVeeVSAjHWm?videoPreview=12025-07-17T14:00:00+00:001692.04Topics at the heart of our communityArtificial Intelligence (AI) has transformed the research publishing landscape. As an editor, you are now faced with AI-related challenges, some of which include image integrity, paper mills, and plagiarism. Join Tamara Welschot, Head of Research Integrity, Prevention, Cristiano Matricardi, Head of Content Innovation, who will discuss how we are harnessing the power of AI to support our editors in meeting the increasing demands for innovation and quality within scholarly publishing. https://cassyni-user-files-prod.s3.amazonaws.com/CUTicX3Uyjdp4gAttBA2wQ https://cassyni.com/events/PootMFNC2BcohytEqBr3gR/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4mhheSeFJdXxK6tpiZkRjc https://cassyni.com/slides/outline/DSZHs5Uh3G2nQmTwaCpW9s https://cassyni.com/events/DSZHs5Uh3G2nQmTwaCpW9s/abstract https://cassyni-user-files-prod.s3.amazonaws.com/j8pqeSKGihBkiBHmgT36v https://cassyni.com/events/DSZHs5Uh3G2nQmTwaCpW9s?videoPreview=1 How do Chinese-English Learners Process Metaphorical Actionsnohttps://cassyni.com/events/DSZHs5Uh3G2nQmTwaCpW9s?videoPreview=12025-10-03T00:10:00+00:002620.04Linguistics and Applied Language StudiesBodily action plays a crucial role in human interaction with the world and provides a foundation for comprehending abstract concepts. This study examined how Chinese-English speakers process familiar and less familiar metaphorical actions. Using a sentence-priming paradigm, participants read action-related sentences (literal, familiar metaphorical, and less familiar metaphorical), each immediately followed by a target word associated with either the verb’s literal or figurative meaning. Participants performed a lexical decision task by pressing response keys. Results showed that familiar metaphorical action sentences facilitated recognition of target words related to figurative meanings compared to control words, whereas less familiar metaphorical action sentences facilitated recognition of target words related to literal meanings. These findings suggest that Chinese-English speakers process familiar and less familiar metaphorical actions differently and provide support for the Graded Salience Hypothesis of figurative language processing.https://cassyni-user-files-prod.s3.amazonaws.com/j8pqeSKGihBkiBHmgT36v https://cassyni.com/slides/outline/CTG5miBeALvdk1dwUEMBLy https://cassyni.com/events/CTG5miBeALvdk1dwUEMBLy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5QpnfXWz3fPEmhNBStSNzA https://cassyni.com/events/CTG5miBeALvdk1dwUEMBLy?videoPreview=1 Microstructure Engineering Techniques for Additive (META)nohttps://cassyni.com/events/CTG5miBeALvdk1dwUEMBLy?videoPreview=12025-06-20T13:00:00+00:002660.64UK Metamaterials NetworkFusion-based additive manufacturing techniques such as laser powder bed fusion (LPBF), offer a powerful platform for tailoring the microstructure of metallic components in a site-specific manner through localised control of the processing parameters. This capability enables the production of parts that integrate distinct, often incompatible, functionalities within a single build—overcoming the limitations of conventional monolithic materials. As such, this paradigm is particularly well suited for the design and manufacturing of metamaterials, whose properties are both geometry- and microstructure-dependent. In this talk, I will showcase different examples of microstructure control using LPBF. I will discuss the underpinning metallurgical mechanisms and provide practical examples using different steel alloys. Finally, I will discuss the broader implications of this approach for advanced component design in critical engineering sectors.https://cassyni-user-files-prod.s3.amazonaws.com/5QpnfXWz3fPEmhNBStSNzA https://cassyni.com/events/43siVuVCTsU9zwtBp4KKQZ/seminar/qa https://cassyni.com/slides/outline/43siVuVCTsU9zwtBp4KKQZ https://cassyni.com/events/43siVuVCTsU9zwtBp4KKQZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PAzB2ifJxsYWWyjHC4zp1C https://cassyni.com/events/43siVuVCTsU9zwtBp4KKQZ?videoPreview=1 Social and Environmental Determinants of Health in Dialysis 1400-1530nohttps://cassyni.com/events/43siVuVCTsU9zwtBp4KKQZ?videoPreview=12025-09-18T13:00:00+00:005994.28Imperial College Renal and Transplant Centre1400 Social Prescription - empowering everyone involved in care, Michelle Delon Renal Social Worker, ICHNT 1445 Environment Factors and the influence on the health of people on dialysis, Peter Kotanko, Emeritus Research Director at the Renal Research Institute, New York Image credit: [Wilmer Martinez (Unsplash)](https://unsplash.com/photos/three-woman-standing-in-convenience-storefront-aPEVwpqhQgU).https://cassyni-user-files-prod.s3.amazonaws.com/PAzB2ifJxsYWWyjHC4zp1C https://cassyni.com/events/3Y7Ct3EDuyrwmDJ3FzpjWV/seminar/qa https://cassyni.com/slides/outline/3Y7Ct3EDuyrwmDJ3FzpjWV https://cassyni.com/events/3Y7Ct3EDuyrwmDJ3FzpjWV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Aa6LRVhpLLHfDXYUggqZGi https://cassyni.com/events/3Y7Ct3EDuyrwmDJ3FzpjWV?videoPreview=1 Collective behavior and function in motile cell assembliesnohttps://cassyni.com/events/3Y7Ct3EDuyrwmDJ3FzpjWV?videoPreview=12025-08-21T14:00:00+00:005209.36Journal of Biological PhysicsInteractions between migrating cells can lead to emergent, collective structures and dynamical phases that are critical for function and mediate many physiological processes such as embryonic development, wound healing, and cancer metastasis. In this talk, I shall first describe our work on modeling such phenomena in cancer cell clusters, highlighting how frustration can arise at the group level because of heterogeneity in behavior and cohesion among individual cells in the cluster. I shall show how this frustration can be resolved leading to new collective phases of motion as well as instabilities that are experimentally observed in malignant lymphocyte clusters and functionally important – enabling robust chemotaxis and “load sharing” among cells. I will also briefly discuss work showing how long-range substrate-mediated mechanical interactions between cells can lead to the formation of branched network structures. I shall discuss our prediction that cell network formation is substrate stiffness-dependent, being optimal at intermediate stiffness, which we confirmed with experiments. Our work suggests that long-range interactions can lead to more robust and efficient realization of space-spanning networks than with cell-cell contact interactions alone. Finally I will discuss some open questions and potential future directions in these areas.https://cassyni-user-files-prod.s3.amazonaws.com/Aa6LRVhpLLHfDXYUggqZGi https://cassyni.com/events/PnkE1KnWiURC7iL5Ejuw6d/seminar/qa https://cassyni.com/slides/outline/PnkE1KnWiURC7iL5Ejuw6d https://cassyni.com/events/PnkE1KnWiURC7iL5Ejuw6d/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CZMGMPeVpb22qqtSrtz1KL https://cassyni.com/events/PnkE1KnWiURC7iL5Ejuw6d?videoPreview=1 JWPE Publication Workshop 2025 (online)nohttps://cassyni.com/events/PnkE1KnWiURC7iL5Ejuw6d?videoPreview=12025-10-07T11:00:00+00:006772.08ElsevierJoin us for an exclusive JWPE Online Publication Workshop designed to help you navigate the publishing process with confidence. Hosted by the Journal of Water Process Engineering, this 90 minute interactive event will provide essential insights into academic publishing from leading editors and researchers. The workshop opens with an introduction to JWPE by Drs Luaine Bandounas and Ludovic Dumée, covering the journal’s scope, mission, and editorial process. You’ll gain a clear understanding of submission trends, quality standards, and the most common reasons for rejection, as well as how plagiarism is monitored and how to appropriately resubmit after rejection. Importantly, we’ll also discuss the growing role of AI in scientific publishing—highlighting smart, ethical ways to integrate it into your writing. Next, Professor Dumée will share practical tips for crafting a high-quality paper, including how to write a compelling cover letter, structure your manuscript for clarity, and design impactful figures, tables, and graphical abstracts. The session continues with a live panel discussion featuring senior editors Prof. Alicia An, Prof. Laura Bulgariu and Dr Mohammad Mahdi (Mehdi) A. Shirazi, who will share their perspectives on what truly makes a paper stand out. The workshop concludes with an open Q&A, giving you the chance to engage directly with editors and get tailored advice. This workshop is open to students, early-career researchers, and established academics alike. Register now to sharpen your publishing skills and increase your chances of success in JWPE.https://cassyni-user-files-prod.s3.amazonaws.com/CZMGMPeVpb22qqtSrtz1KL https://cassyni.com/events/JMcaVofjtSL7ir5qdpv97B/seminar/qa https://cassyni.com/slides/outline/JMcaVofjtSL7ir5qdpv97B https://cassyni.com/events/JMcaVofjtSL7ir5qdpv97B/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9QJuGvB1CW8TibQ4f8XJEi https://cassyni.com/events/JMcaVofjtSL7ir5qdpv97B?videoPreview=1 Why Diversity, Equity and Inclusion are of utmost importance for the field of Community Genetics/Public Health Genomicsnohttps://cassyni.com/events/JMcaVofjtSL7ir5qdpv97B?videoPreview=12025-11-17T15:00:00+00:005211.6Research Seminars by Springer NatureWhen applying medical genetics to human communities, it is important to consider diversity in terms of biological differences and differences in health care systems, equity in terms of accommodating the different needs of different people and inclusion, implying that no one is left behind. Recent discussions in the USA have questioned diversity, equity, and inclusion (DEI) and several government programs and grants have been terminated. For SpringerNature and its Journal of Community Genetics, as well as for Karger’s journal Public Health Genomics, DEI concepts are at the heart of its mission. The journals contribute to the Sustainable Development Goals (SDGs) Goal 3 - Good Health and Wellbeing, Goal 4 - Quality Education, and Goal 10 - Reduced Inequalities - respectively. A recent example is the JoCG Special Issue on Community Genetics in Brazil, describing how the field has developed over the last decades, paying attention to the needs of Brazil’s inhabitants. Image credit: [digitale.de (Unsplash)](https://unsplash.com/photos/a-close-up-of-a-single-strand-of-food-uD98M9OhNmc).https://cassyni-user-files-prod.s3.amazonaws.com/9QJuGvB1CW8TibQ4f8XJEi https://cassyni.com/slides/outline/PK735Jgtn1DD4pS6qQtubK https://cassyni.com/events/PK735Jgtn1DD4pS6qQtubK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4w6hvKzVKDR931HQDg5Gn2 https://cassyni.com/events/PK735Jgtn1DD4pS6qQtubK?videoPreview=1 Acceptor Caged Phosphine Ligands: Exploration of Novel Catalytic Reactivity and Mechanismnohttps://cassyni.com/events/PK735Jgtn1DD4pS6qQtubK?videoPreview=12024-08-07T13:00:00+00:003089.24Thieme India ChemTalksPhosphines as activating ligands have, in combination with transition metals, played an important role in the development of sustainable catalytic solutions for academia as well as industrial applications. Caged phosphines are a class of phosphines possessing three-dimensional scaffolds and capable of providing unique control over steric and electronic properties. The versatility of the caged phosphine ligands has been demonstrated elegantly by the groups of Verkade, Gonzalvi as well as Stradiotto [1]. Our contribution to this area comes in the form of the 1,3,5-triaza-7-phosphaadamantane-based caged ligands, especially PTABS (KapdiPhos) that has proved to be a revelation in promoting heteroarene functionalization in a highly efficient way. The talk will therefore be centered around the journey from the development of the ligand to the varied applications including scale-up possibilities, eventually culminating into its commercialization [2]. New catalytic reactivity and its mechanism has been explored along the way and will also be discussed.https://cassyni-user-files-prod.s3.amazonaws.com/4w6hvKzVKDR931HQDg5Gn2 https://cassyni.com/events/UEafRUcEfbQSaN5s9PgWF7/seminar/qa https://cassyni.com/slides/outline/UEafRUcEfbQSaN5s9PgWF7 https://cassyni.com/events/UEafRUcEfbQSaN5s9PgWF7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/14cjeSyHTpqFAdMDMwucr https://cassyni.com/events/UEafRUcEfbQSaN5s9PgWF7?videoPreview=1 Spacetime on the Move: Gravitational Waves as Travelling-Wave Modulationsnohttps://cassyni.com/events/UEafRUcEfbQSaN5s9PgWF7?videoPreview=12025-11-04T14:00:00+00:003582.56MetaMATGravitational waves leave subtle yet measurable imprints when interacting with light in relative motion. In this talk, I will present a fully covariant coupled-wave framework that treats gravitational waves as luminal moving gratings which dynamically modulate the local refractive index of spacetime. This modulation gives rise to sidebands in the spectrum of forward-propagating electromagnetic radiation in a plasma, an intrinsically directional effect that conserves both energy and momentum while imposing no coherence requirements on the interacting fields. I will show how this mechanism not only preserves the directional signature of gravitational waves but also offers pathways for exploiting incoherent radiation sources such as the cosmic microwave background. Beyond astrophysical contexts, I will discuss how synthetic travelling-wave modulations engineered in meta-optical systems can emulate these spacetime-induced interactions. In particular, I will outline an all-optical analogue platform for mimicking Brillouin-like forward scattering of light by spacetime distortions, thereby enabling laboratory exploration of gravitational-wave–photon coupling and its technological implications.https://cassyni-user-files-prod.s3.amazonaws.com/14cjeSyHTpqFAdMDMwucr https://cassyni.com/slides/outline/AUFKsXsFN6pLrbRdBiw7U9 https://cassyni.com/events/AUFKsXsFN6pLrbRdBiw7U9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Pcb4orALerXKXCBNbaPp9t https://cassyni.com/events/AUFKsXsFN6pLrbRdBiw7U9?videoPreview=1 The Good Metascience Project: Goal setting and emerging technologies to make science funders more impactfulnohttps://cassyni.com/events/AUFKsXsFN6pLrbRdBiw7U9?videoPreview=12025-06-24T16:00:00+00:005195.0This 90 minute panel and audience discussion presents highlights from the Good Science Project R&D Reform recommendations. After a brief introduction by Stuart Buck about this policy effort, Neil Thakur will outline the concept of setting agency wide funding goals aligned with the impact portion of the a funder’s mission (e.g. “improve health, extend life, and reduce illness and disability” for NIH, “Advance the national health, prosperity and welfare [and] secure the national defense” for NSF) and discuss how they can lead to investment changes within specific portfolios, across multiple areas of science, and across multiple time scales. Leslie McIntosh will describe the broad array of new portfolio selection, management, and evaluation tools that could be enabled by applying AI techniques to an integrated database of all federal research projects. She will outline the benefits of this data integration, and how the enabled analytic capacity could drive benefits including accelerated discovery and collaboration, increased efficiency and accountability, and reduced waste. Michael Stebbins and Neil Thakur will present a more specific use of AI tools by applying them to federal grant applications. They will describe how these data can predict the future of scientific and technological breakthroughs, enhance peer review, and encourage better research investments by both the public and the private sector. All presentations will be completed within 45 minutes, followed by audience discussion lead by Stuart Buck.https://cassyni-user-files-prod.s3.amazonaws.com/Pcb4orALerXKXCBNbaPp9t https://cassyni.com/events/EQRk8LVYNmtxwBdAEiL6WH/seminar/qa https://cassyni.com/slides/outline/EQRk8LVYNmtxwBdAEiL6WH https://cassyni.com/events/EQRk8LVYNmtxwBdAEiL6WH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2cVy2KHSJQTotgjv15yLy4 https://cassyni.com/events/EQRk8LVYNmtxwBdAEiL6WH?videoPreview=1 Universal power-law distribution functions in an electromagnetic kinetic plasma: implications for the inverted temperature profile in the solar coronanohttps://cassyni.com/events/EQRk8LVYNmtxwBdAEiL6WH?videoPreview=12025-10-16T15:00:00+00:003397.2Journal of Plasma PhysicsThere is ample evidence for non-thermal power-law distribution functions in space and astrophysical plasmas in the collisionless/kinetic regime, with a preference for the v^-5 velocity (v) distribution and E^-2 energy (E) distribution in the solar wind. We have developed a self-consistent quasilinear theory for particle acceleration in weakly collisional plasmas, based on the perturbed Vlasov-Maxwell equations, that yields a transport equation for the combined relaxation of the electron and ion distribution functions. The theory predicts that a weakly collisional plasma tends to relax to a v^-5 distribution function (E^-2 energy distribution) for both species, if it is subject to white noise-like electromagnetic turbulence on super-Debye scales, independent of the detailed power spectrum. Stronger Debye shielding of slower particles reduces their effective charge and suppresses their acceleration relative to the unshielded faster particles in a near-universal manner, leading to this power-law tail. The presence of such a power-law distribution function in the weakly collisional solar corona can potentially solve the coronal heating problem. Large-scale electromagnetic turbulence can trigger the ~v^-5 suprathermal tail at the coronal base. This allows gravity to let the suprathermal particles escape (velocity filtration), inverting the temperature profile and heating the plasma to a million degrees K in the corona.https://cassyni-user-files-prod.s3.amazonaws.com/2cVy2KHSJQTotgjv15yLy4 https://cassyni.com/events/MLYF1CcgRXvYXLx45q7F3b/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EbHC32QLWAh5qnW8NEXQxE https://cassyni.com/events/9TwhfW2HzCMwY5upEEd6n9/seminar/qa https://cassyni.com/slides/outline/9TwhfW2HzCMwY5upEEd6n9 https://cassyni.com/events/9TwhfW2HzCMwY5upEEd6n9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CgWfcZZNvxA4G6DDzHH8xE https://cassyni.com/events/9TwhfW2HzCMwY5upEEd6n9?videoPreview=1 Aqueous phase reforming of wastewater streams: a multi-scale perspective towards renewable hydrogennohttps://cassyni.com/events/9TwhfW2HzCMwY5upEEd6n9?videoPreview=12025-10-29T10:00:00+00:003394.96ElsevierValorizing wastewater is a central challenge for chemical engineering and a lever for the UN Sustainable Development Goals. This webinar focuses on how aqueous phase reforming (APR) can transform carbon-laden water streams into hydrogen through a multi-scale lens, from molecules to reactors to systems. At the molecular scale, we will show how density functional theory illuminates competitive adsorption and non-linear lateral interactions that arise in realistic, multicomponent mixtures, providing mechanistic explanations for trends often masked in mono-component studies. From there, we transition to reaction engineering and implementation. We compare batch and continuous configurations and discuss rigorous product characterization as a prerequisite for closing mass and carbon balances. Sector-specific case studies (bioethanol side streams, food industry effluents, and hydrothermal wastewater fractions) illustrate how feed composition shapes opportunities and constraints. Particular attention is given to catalyst deactivation and to mitigation strategies. Finally, since credible decision-making requires system-level evidence, we frame APR with early-stage techno-economic and environmental assessments. While provisional at low TRL, TEA/LCA guide optimization, uncertainty/sensitivity priorities, and scale-up choices, while point out synergies between APR, hydrothermal liquefaction, and sustainable aviation fuel pathways.https://cassyni-user-files-prod.s3.amazonaws.com/CgWfcZZNvxA4G6DDzHH8xE https://cassyni.com/slides/outline/QHRTAdwvZHu1wBKb2r2uGq https://cassyni.com/events/QHRTAdwvZHu1wBKb2r2uGq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/E8xMzSLSBmTeenu9vi8hYr https://cassyni.com/events/QHRTAdwvZHu1wBKb2r2uGq?videoPreview=1 Drought-induced photosynthetic decline and increased heat dissipation complicate SIF-based analysis of ecosystem responses to climatenohttps://cassyni.com/events/QHRTAdwvZHu1wBKb2r2uGq?videoPreview=12025-08-05T08:30:00+00:00849.24NoneAmazonian forests have faced extreme droughts in recent decades often linked to El Niño events, leading to increased tree mortality, reduced carbon sequestration, and sharp rises in global atmospheric CO₂ levels. The extent to which photosynthetic drought sensitivity varies across the vertical canopy profile in Amazonian forests remains poorly quantified, despite its potential importance for these forest-wide responses. Here, we show that photosynthetic capacity and photoprotective responses vary significantly across canopy strata during drought events. Using vertical canopy sampling of chlorophyll fluorescence in mature leaves, we analyzed seasonal and drought-induced changes during the 2023-2024 El Niño Southern Oscillation (ENSO) drought. Reductions in photosynthetic electron flow occurred in mid (20–40 m) and upper (>40 m) canopy layers, alongside changes in photochemical efficiency (ΦPSII), non-photochemical quenching (ΦNPQ), and steady-state leaf fluorescence (ΦNO). The ΦNPQ/ΦNO ratio increased across all strata under drought stress, indicating enhanced photoprotection. However, photosynthesis relative to fluorescence declined, indicating a shifting SIF-GPP relationship during extreme drought that must be accounted for when using SIF remote sensing to assess canopy responses to climate extremes.https://cassyni-user-files-prod.s3.amazonaws.com/E8xMzSLSBmTeenu9vi8hYr https://cassyni.com/events/KLwQhoUgAiMzY5cF2NKuYh/seminar/qa https://cassyni.com/slides/outline/KLwQhoUgAiMzY5cF2NKuYh https://cassyni.com/events/KLwQhoUgAiMzY5cF2NKuYh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/C2QnE7vpSpPY7e9kSRV4zA https://cassyni.com/events/KLwQhoUgAiMzY5cF2NKuYh?videoPreview=1 Cannabinoid Pharmacology and Neuroinflammationnohttps://cassyni.com/events/KLwQhoUgAiMzY5cF2NKuYh?videoPreview=12026-07-02T11:00:00+00:005579.8The Pharmacological Research family of journalsThe endocannabinoid system (ECS) has emerged as a key regulator of brain function, especially in the context of stress, neuroinflammation, and emotional behavior. In this seminar I will explore the interface between cannabinoid pharmacology and neuroimmunology. The presentation will begin with an introduction to the ECS, highlighting its distinctive features as an “atypical neurotransmitter” system, its expression in both neurons and glial cells, and its role in modulating stress responses and fear conditioning. I will then present experimental evidence showing that stress exposure in rodents induces a neuroinflammatory profile in stress-related brain regions that can be modulated by cannabinoids. Further mechanistic insight comes from studies using genetically modified mice that exhibit PTSD-like phenotypes, and pharmacological strategies promoting FAAH inhibition or TRPV1 antagonism. Last, but not least, I will present evidence on the possible involvement of ECS in the anti-stress effect induced by inhibition of immune system molecules. Despite challenges in translating animal models to humans, our data and results from many other groups consistently support the view that cannabinoids modulate stress responses at least partly through immune-mediated mechanisms. By the end of the seminar, I expect to have provided a comprehensive update on how ECS-targeted strategies may open new avenues for treating stress-related neuropsychiatric disorders such as PTSD, and on the potential role of immune mechanisms in these effects.https://cassyni-user-files-prod.s3.amazonaws.com/C2QnE7vpSpPY7e9kSRV4zA https://cassyni.com/slides/outline/ac59rjgsDmtpJx14haWmj https://cassyni.com/events/ac59rjgsDmtpJx14haWmj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6nDvAE3b42movT3FXAnxmL https://cassyni.com/slides/outline/DvpBJwuoqfckhzBp349Eus https://cassyni.com/events/DvpBJwuoqfckhzBp349Eus/abstract https://cassyni-user-files-prod.s3.amazonaws.com/W5hD5KYKGwUVkja36mKX8a https://cassyni.com/events/DvpBJwuoqfckhzBp349Eus?videoPreview=1 Same Tech, Different Outcomes: Igniting Your GenAI with the PPPP Blueprintnohttps://cassyni.com/events/DvpBJwuoqfckhzBp349Eus?videoPreview=12025-04-29T23:00:00+00:003484.6Business SchoolWhy does the same powerful technology lead to game-changing success in one organisation but costly setbacks in another? It is rarely about the AI tool itself. Recent examples reveal that even when Generative AI performs impressively on paper, outcomes can vary dramatically depending on how well the technology complements or conflicts with an organisation’s strategy, culture, operations, and offerings. Join us as we explore what separates strategic wins from misaligned deployments, and why context is everything. Drawing from Air New Zealand’s journey with business intelligence and AI, we introduce the PPPP framework (People, Process, Place, and Product) as a blueprint to guide GenAI adoption and accelerate value. Through this session, we show how alignment across these four dimensions can help unlock value faster and ensure that advanced technologies become truly transformative tools, rather than costly distractions.https://cassyni-user-files-prod.s3.amazonaws.com/W5hD5KYKGwUVkja36mKX8a https://cassyni.com/slides/outline/GQ4CYN9S2xPF4vfNak3sdo https://cassyni.com/events/GQ4CYN9S2xPF4vfNak3sdo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Pp7aRwaG1cBitWosuV6UB8 https://cassyni.com/events/GQ4CYN9S2xPF4vfNak3sdo?videoPreview=1 DNS and High Reynolds Number Experiments Lead to New Insights for Overlap Region and Near-Wall Layer of Wall-Bounded Turbulencenohttps://cassyni.com/events/GQ4CYN9S2xPF4vfNak3sdo?videoPreview=12025-07-16T13:00:00+00:003033.24Department of Aeronautics and AstronauticsThe modeling, prediction and control of turbulent flows through ducts and over surfaces require accurate information on the overlap region between the near wall turbulence and the outer parts of the flow. After nearly a century of utilizing "classical" relations to represent the overlap region in mean flow and in turbulence, new developments could bring a fresh "movement" in a field impacting many applications including energy saving, efficient transportation and future of environment. With a fresh look at matched asymptotic approximations, together with employing the best available DNS data in channel and pipe flows, as well as experimental data in boundary layer and pipe flows, we develop new directions in our understanding of overlap regions. For the mean velocity profiles, a logarithmic plus linear overlap is found to be superior to the classical pure logarithmic one, and confirms the non-universality of the overlap parameters, including the Kármán coefficient, which are found to depend on flow geometry and pressure gradient. The self-similarity of the logarithmic plus linear overlap is demonstrated using several data sets, including those from the Superpipe, and to improve on the pure logarithmic overlap, because of the wider overlap region for the same Reynolds numbers. For the streamwise normal stress, the defect power trend, based on bounded dissipation is compared to the commonly used inverse logarithmic representation, developed by the wall-scaled eddy model. The evaluation of the two models is carried out using indicator functions for DNS results, in channel and pipe flows, and a new approach is found more suitable for experimental data. The method, which is simple and robust, is used to evaluate each model over a wide range of Reynolds number by applying it to two of the prominent experimental data sets in zero-pressure-gradient boundary layers (ZPG) and pipe flows. Ranges of validity for each of the two models are established both in the overlap region and in the near wall layer of the flows, revealing new understanding of dominant scales and viscous effects.https://cassyni-user-files-prod.s3.amazonaws.com/Pp7aRwaG1cBitWosuV6UB8 https://cassyni.com/slides/outline/8zL8r7SZT65jJtUU2aSFBj https://cassyni.com/events/8zL8r7SZT65jJtUU2aSFBj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CpYJk2Eh4m43JAfJ2FbYrS https://cassyni.com/events/8zL8r7SZT65jJtUU2aSFBj?videoPreview=1 Hitting the Sweet Spot with Digital Transformationnohttps://cassyni.com/events/8zL8r7SZT65jJtUU2aSFBj?videoPreview=12021-09-27T23:00:00+00:003571.04Business SchoolDigital transformation is essential for organisations to remain relevant, build trust, and address critical challenges posed by technology-fueled globalisation. A study outlines a comprehensive approach to digital transformation, highlighting the need to shift from viewing learning as an expense to an investment and to proactively upskill the workforce to mitigate risks such as job displacement and rising inequality. Analysis of internal processes revealed a 40% increase in data volumes, 60% reliance on manual spreadsheets, 60% of time spent on data preparation, 80% unstructured data, and 88% of data unanalysed due to skill gaps. The approach integrates a business-led strategy, aligned with strategic pillars, and a citizen-led initiative focused on broad workforce upskilling. The business-led component involves the integration of external solutions, automation tools (e.g., UI Robots), knowledge management (chatbots), and digital product development. The citizen-led aspect encompasses the "Reimagine Digital" program, featuring a Digital Accelerator program for early adopters (40+ trained in design thinking, data analytics, and agile skills), Digital Academies for broad data visualisation and manipulation training (600+ participants), and a Digital Fitness app for continuous learning (adopted by 150+ companies and ~600 employees). A scaled agile framework structures project delivery, ensuring alignment from portfolio-level strategy to individual KPIs through two-week sprints and quarterly planning. Key successes include significant efficiency gains, with 3300 hours saved by Digital labs and 21,000 hours saved through automation, alongside the deployment of over 300,000 automation processes. The Digital Accelerator program has been instrumental in internal process disruption, such as in transfer pricing, and in delivering value-added client services, exemplified by automated financial performance analysis using Alteryx and Power BI. This transformation fosters continuous learning, encourages a growth mindset, and establishes Centres of Excellence, promoting mastery in fields like AI and data science. The findings underscore the importance of cultural change, foundational technological infrastructure, and strategic upskilling to drive successful digital transformation.https://cassyni-user-files-prod.s3.amazonaws.com/CpYJk2Eh4m43JAfJ2FbYrS https://cassyni.com/events/NoWG9DXEeHAQPUNRshY2zR/seminar/qa https://cassyni.com/slides/outline/NoWG9DXEeHAQPUNRshY2zR https://cassyni.com/events/NoWG9DXEeHAQPUNRshY2zR/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JysZ1tkZEp7RFm7dWDmRC2 https://cassyni.com/events/NoWG9DXEeHAQPUNRshY2zR?videoPreview=1 Exciting times: high-fidelity modeling of living tissues nohttps://cassyni.com/events/NoWG9DXEeHAQPUNRshY2zR?videoPreview=12026-01-15T13:00:00+00:003175.04MOX Laboratory - Department of MathematicsOver the last three decades, advances in bioimaging have revolutionized our ability to study the structure and function of living systems. At the nano- to microscale, the new capabilities of cellular microscopy have resulted in the generation and wide availability of large-scale high-resolution imaging data, as strikingly exemplified by increasingly complex dense reconstructions of cortical tissue. In parallel, research in scientific computing and computational mathematics have led to the development of highly accurate, efficient and scalable numerical algorithms and their realization in open scientific software. In this talk, I will show how we, in the last few years, have developed high-fidelity computational models of cellular and subcellular physiology, incorporating detailed geometric structure, biophysical dynamics and advanced cell imaging data. I will highlight key numerical challenges - some that we have tackled and some open problems - and point at future directions.https://cassyni-user-files-prod.s3.amazonaws.com/JysZ1tkZEp7RFm7dWDmRC2 https://cassyni.com/slides/outline/JsKqtQtwdc5nJtAtpi93xH https://cassyni.com/events/JsKqtQtwdc5nJtAtpi93xH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Qu6RL48yZJgkatzibovJqt https://cassyni.com/events/JsKqtQtwdc5nJtAtpi93xH?videoPreview=1 Toying with acoustic underflow: Nonreciprocal sound propagation in fluid flownohttps://cassyni.com/events/JsKqtQtwdc5nJtAtpi93xH?videoPreview=12025-06-17T05:00:00+00:001944.0ETOPIMAcoustic wave propagation in the presence of fluid flow is a well-known phenomenon that leads to nonreciprocal sound transmission, breaking time-reversal symmetry. This effect has been widely studied in classical acoustics and hydrodynamics, with foundational discussions available in texts such as Fundamentals of Acoustics by Kinsler et al. and Acoustics: An Introduction to Its Physical Principles and Applications by Pierce. In this presentation, I will discuss three distinct research directions explored by my group that leverage fluid flow to control and manipulate acoustic waves. To minimize turbulence, our experimental and theoretical setups consist of a quiescent fluid confined within a duct, which is sandwiched between two uniform half-spaces supporting parallel background flow. This configuration allows for a controlled study of nonreciprocal wave dynamics while maintaining analytical and experimental tractability. As a first case study [1], I will present a theoretical investigation of an intriguing form of acoustic nonreciprocity that arises when the background flow is transverse to the direction of wave propagation. Unlike conventional convective nonreciprocity, which results from the Doppler effect in co- and counter-propagating waves, this scenario demonstrates a unique flow-induced asymmetric mode conversion mechanism. The results provide insight into how shear flows and transverse velocity gradients influence sound wave transmission, potentially offering new avenues for acoustic wave control in aerospace and underwater applications. As a second example, I will discuss experimental results demonstrating acoustic isolation in a duct embedded within a randomly structured medium. By introducing disordered acoustic scatterers inside the duct, we enhance wave dispersion and reflection asymmetries, leading to highly directional energy transport. This approach exploits a combination of flow-induced biasing and multiple scattering effects, drawing connections to the broader fields of wave localization and nonreciprocal metamaterials. Finally, I will discuss a theoretical framework for achieving sectorial one-way wave propagation in a two-dimensional system. This phenomenon occurs when the fluid flow in the upper and lower half-spaces is directed in different directions, inducing spatially varying nonreciprocity. We demonstrate that under appropriate conditions, acoustic waves can be confined and guided along specific angular sectors, effectively creating a tunable one-way sound corridor. https://cassyni-user-files-prod.s3.amazonaws.com/Qu6RL48yZJgkatzibovJqt https://cassyni.com/slides/outline/VEwXrmUxrDiCqPU2qp5wdo https://cassyni.com/events/VEwXrmUxrDiCqPU2qp5wdo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VqaTntcDwtDmyzi4cHdJa2 https://cassyni.com/events/VEwXrmUxrDiCqPU2qp5wdo?videoPreview=1 Wave basis of Ohm’s law: observation and impact of transmission and velocity zerosnohttps://cassyni.com/events/VEwXrmUxrDiCqPU2qp5wdo?videoPreview=12025-06-18T03:00:00+00:002113.0ETOPIMThe quantum conductance and its classical wave analogue, the transmittance, are given by the sum of the eigenvalues of the transmission matrix. Here, we measure spectra of microwave transmission matrices of random waveguides and find the spectra of all transmission eigenvalues, even at dips in the lowest transmission eigenchannel that are ten orders of magnitude below the noise in the transmission matrix. Transmission vanishes both at topological transmission zeros, at which the energy density at the sample output vanishes, and at crossovers to new channels, where the longitudinal velocity vanishes. The longitudinal velocities of diƯerent transmission eigenchannels are distinct and independent of length for samples longer than the mean free path. The statistics of the eigenchannel velocities on the incident and output surfaces of the sample are identical. Zeros of transmission pull down all the transmission eigenvalues and thereby produce dips in the transmittance. These dips and the ability to probe the characteristics of even the lowest transmission eigenchannel are due to correlation among the eigenvalues. The precise tracking of dips in the conductance by peaks in the density of states points to a further correlation between zeros and poles of the transmission matrix. The conductance approaches Ohm’s law as the sample width increases in accord with the correspondence principle. https://cassyni-user-files-prod.s3.amazonaws.com/VqaTntcDwtDmyzi4cHdJa2 https://cassyni.com/slides/outline/RnQJXyxHn1qZohAUC9hz6y https://cassyni.com/events/RnQJXyxHn1qZohAUC9hz6y/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DR281AM2MQpUhvtMm4T4gW https://cassyni.com/events/RnQJXyxHn1qZohAUC9hz6y?videoPreview=1 Source-driven homogenization theory for electro-momentum coupled scatterersnohttps://cassyni.com/events/RnQJXyxHn1qZohAUC9hz6y?videoPreview=12025-06-19T23:00:00+00:001865.16ETOPIMWillis materials are metamaterials whose subwavelength asymmetry couples the macroscopic pressure-strain and momentum-velocity relations1. Recently, the design space of these metamaterials has been expanded to consider additional field coupling such as poroelasticity 2 and piezoelectricity. Of interest in this work is the case of subwavelength asymmetric piezoelectric scatterers in a background material which has been shown to couple the electric field-electric displacement relation to the constitutive equations in the Willis form 3,4. The existence of this so-called electro-momentum coupling was first predicted using dynamic homogenization of heterogeneous piezoelectric media1-3 but it can also be understood through a generalized polarizability tensor 𝛂 that calculates the electro-acoustic field scattered from a single asymmetric piezoelectric inhomogeneity as a function of local fields. We present a multiple-scattering dynamic homogenization method that extends the work of Sieck et al.5 using the generalized polarizability tensor6,7. The model considers the microscale scattered pressure, velocity, and electric fields in a one-dimensional periodic lattice of identical scatterers to find analytical expressions for the effective macroscale fields. The macroscale fields are then used to find the effective electro-momentum coupling constants in terms of the polarizability of the individual scatterers and the concentration of scatterers in a background medium. The resulting expressions for the effective properties obey constraints imposed by reciprocity and passivity and demonstrate an emergent magneto-momentum coupling even in absence of piezomagnetic coupling or electromagnetic bianisotropy at the microscale.https://cassyni-user-files-prod.s3.amazonaws.com/DR281AM2MQpUhvtMm4T4gW https://cassyni.com/slides/outline/53AvbGnFLnaJfhiBv2neDT https://cassyni.com/events/53AvbGnFLnaJfhiBv2neDT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EF8mrZsNAoonKidMQWyGCN https://cassyni.com/events/53AvbGnFLnaJfhiBv2neDT?videoPreview=1 Trees struggling to reproduce as climate shiftsnohttps://cassyni.com/events/53AvbGnFLnaJfhiBv2neDT?videoPreview=12025-07-09T12:00:00+00:001757.04NoneTraditionally, forest ecology has focused primarily on tree growth and mortality, while seed production—crucial to population demography—remains poorly understood, particularly in the context of climate change. Understanding how climate change affects tree reproduction is complicated by the phenomenon of mast seeding—periods of high seed production synchronized across individuals and populations. I will present research on the impact of climate warming on mast seeding in European beech (_Fagus sylvatica_). Climate warming disrupts beech mast cycles by reducing both interannual variability and synchrony. As a result, the mast seeding strategy becomes less effective. In populations monitored for over 40 years in England, average seed predation by insects has risen from about 1% to 40%, while pollination success has dropped from around 50% to 33%. The largest individuals are most affected, likely due to their susceptibility to self-pollination, which can only be prevented by synchronous flowering within the population. Additionally, increased frequency of seed production leads to chronic resource depletion, resulting in a 28% decline in tree growth. Studies across the species’ range show that this “mast seeding breakdown” is widespread and strongly linked to rising temperatures, especially in summer. This suggests that the reproductive potential of beech as a foundation forest species may be threatened across its entire distribution. https://cassyni-user-files-prod.s3.amazonaws.com/EF8mrZsNAoonKidMQWyGCN https://cassyni.com/slides/outline/7WQwph1sY5Lo2eBkTihGwP https://cassyni.com/events/7WQwph1sY5Lo2eBkTihGwP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XHccQfkWvYc1vnuxAaCoTU https://cassyni.com/events/7WQwph1sY5Lo2eBkTihGwP?videoPreview=1 Understanding global diversity of arbuscular mycorrhizal fungi leads the way to ecologically literate soil management guidelinesnohttps://cassyni.com/events/7WQwph1sY5Lo2eBkTihGwP?videoPreview=12025-07-10T12:00:00+00:001831.04NoneQuest into biodiversity and community patterns of arbuscular mycorrhizal (AM) fungi first flourished in 1980s and -90s, using the approaches available at that time – identifying spores from soil. With the advent of DNA-based methods in 1990s it became apparent that sporulating AM fungi do not represent fully what these fungi are doing in plant roots and soil. My first contribution to understanding AM fungal diversity in 2003 (in _New Phytologist_) recognised host preference and dealt a lot with developing methods. In the following decades lab and bioinformatical methods and databases developed, data accumulated from many plant species, biomes, regions and patterns emerged. Major shift in understanding AM fungal diversity patterns occurred with next generation sequencing technologies coming to market which changed accuracy of capturing (AM) fungal diversity. In 2010 MaarjAM database of AM fungal sequences was published in _New Phytologist_, 2015 first global study of AM fungi in natural biomes was published resulting from 7 years of fieldwork and a lot of 454 sequencing. To generate the same amount of data now would be much faster. These and following studies demonstrated biome-wise differences in AM fungal diversity and community composition (grasslands vs forests), latitudinal diversity gradient, climatic and edaphic effects, recognised large proportion of “hidden” diversity (not known morphologically), anthropogenic effects, role of tropical grasslands in developing AM fungal species pools. Accumulated DNA-based data of AM fungal occurrences have enabled computing niche properties of AM fungi. My own work with AM fungal diversity has moved from natural systems to agricultural and anthropogenic ones. We can now see the regional scale spatial variation, we are able to generate spatially dense datasets and relate them with agricultural management, crop types, soil types etc. Work on soil biodiversity has also moved from being an environmental activity to something of societal relevance. Therefore we are working together with farmers to develop deeper understanding of soil biodiversity in the society, including farmers, various land managers, policy makers and general public. The basic research approaches and accumulated understanding on AM fungal diversity now allows us to develop applications such as biodiversity-considerate soil management guidelines for farmers, and contribute to fungal, environmental, ecological literacy in the society. https://cassyni-user-files-prod.s3.amazonaws.com/XHccQfkWvYc1vnuxAaCoTU https://cassyni.com/events/JqxLHZeWtvhB74NU8BGkCV/seminar/qa https://cassyni.com/slides/outline/JqxLHZeWtvhB74NU8BGkCV https://cassyni.com/events/JqxLHZeWtvhB74NU8BGkCV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/W7w4Rd63NeZApHVgya6Ka6 https://cassyni.com/events/JqxLHZeWtvhB74NU8BGkCV?videoPreview=1 26th international Biometals Webinarsnohttps://cassyni.com/events/JqxLHZeWtvhB74NU8BGkCV?videoPreview=12026-05-05T13:00:00+00:005720.12BioMetalsThe seminar explored diverse mechanisms underlying bacterial oxidative stress responses and metalloprotein evolution. One study identified PexR as a novel metal-dependent sensor regulating hydrogen peroxide stress in *Myxococcus xanthus*, a soil bacterium lacking canonical PerR or OxyR homologs. PexR, a bacterial enhancer-binding protein, contains an N-terminal GAF-type domain that binds either zinc or iron. In the presence of peroxide, metal release from PexR induces a conformational change, transitioning the protein from an inhibitory state to an active form. This activation drives the σ54-dependent expression of key peroxide-detoxifying enzymes, including alkyl hydroperoxide reductase (AhpC) and catalase (KatB). This regulatory mechanism is conserved across various myxobacteria and beyond, suggesting an ancestral role in peroxide defense. A second study investigated the evolution of metal cofactor preference in the SodFM family of superoxide dismutases (SODs), which utilize either iron or manganese for catalysis. Focusing on the *Staphylococcus aureus* SodA/SodM pair, which share 75% sequence identity, it was demonstrated that the cambialistic SodM emerged through gene duplication and neofunctionalisation from the manganese-dependent SodA. Analysis of 60 SodFMs across the tree of life revealed frequent shifts in metal preference, with specific second-sphere residues identified as crucial for this adaptability. These changes are directly linked to alterations in the enzyme’s reduction potential and resting oxidation state, supporting the redox tuning hypothesis. Furthermore, the neofunctionalised SodM exhibited enhanced structural stability compared to its ancestral counterpart. These findings highlight the dynamic evolutionary landscape of metalloproteins and the complex regulatory strategies governing metal-dependent stress responses.https://cassyni-user-files-prod.s3.amazonaws.com/W7w4Rd63NeZApHVgya6Ka6 https://cassyni.com/events/UEGpAYwVEdDSxoqc3JkK57/seminar/qa https://cassyni.com/slides/outline/UEGpAYwVEdDSxoqc3JkK57 https://cassyni.com/events/UEGpAYwVEdDSxoqc3JkK57/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UJfZ2GEeF9w78jg17EaF2v https://cassyni.com/events/UEGpAYwVEdDSxoqc3JkK57?videoPreview=1 Assessing Monotone Dependence - with Applications to Weather Predictionnohttps://cassyni.com/events/UEGpAYwVEdDSxoqc3JkK57?videoPreview=12026-03-05T13:00:00+00:003186.04MOX Laboratory - Department of Mathematics The assessment of monotone dependence between random variables $X$ and $Y$ is a classical problem in statistics and a gamut of application domains. Consequently, researchers have sought measures of association that are invariant under strictly increasing transformations of the margins, with the extant literature being splintered. Rank correlation coefficients, such as Spearman's rho and Kendall's tau, have been studied at great length in the statistical literature, mostly under the assumption that $X$ and $Y$ are continuous. In the case of a dichotomous outcome $Y$, receiver operating characteristic (ROC) analysis and the asymmetric area under the ROC curve (AUC) measure are used to assess monotone dependence of $Y$ on a predictor $X$. In this talk I demonstrate that the two thus far disconnected strands of literature can be unified and bridged, by developing common population level theory, common estimators, and common tests that apply to all types of linearly ordered outcomes. In a case study, we assess recent progress in artificial intelligence based weather prediction (AIWP) versus traditional numerical weather prediction (NWP). The talk is based on joint work with Eva-Maria Walz and Andreas Eberl. This initiative is part of the “Ph.D. Lectures” activity of the project "Departments of Excellence 2023-2027" of the Department of Mathematics of Politecnico di Milano. This activity consists of seminars open to Ph.D. students, followed by meetings with the speaker to discuss and go into detail on the topics presented during the talk.https://cassyni-user-files-prod.s3.amazonaws.com/UJfZ2GEeF9w78jg17EaF2v https://cassyni.com/slides/outline/KLdZSsovjkAzvXMyvHPiNh https://cassyni.com/events/KLdZSsovjkAzvXMyvHPiNh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/SZGkyosGpEdA6twjW6qYpn https://cassyni.com/events/KLdZSsovjkAzvXMyvHPiNh?videoPreview=1 F3 – Research through the Lens of the SRECNPnohttps://cassyni.com/events/KLdZSsovjkAzvXMyvHPiNh?videoPreview=12026-04-21T09:15:00+00:002671.6Research Analytics SummitResearch through the lens of the SRECNP. The Statement of Revenues, Expenses and Change in Net Position or SRECNP can offer research analytics professionals one way of broadly analyzing an institution of higher education’s research portfolio. The presentation will utilize publicly available financial statement data from Arizona State University (ASU) to see what we can learn about the institution’s research portfolio and management strategy. A basic understanding of the SRECNP will be provided, including how the Government Accounting Standards Board (GASB) recent rules changes offers an opportunity for us to compare and evaluate similar public high research activity institutions. The presentation is designed for those new to research analytics roles as well as professionals with many years of experience. We spend many hours tracking and reporting on research metrics such as award counts and dollars, proposal submissions, funding rates and investigator profiles. Using the tool of Tableau and a novice’s approach to creating a data model, this presentation will look through a different window of publicly available financial statement components to shine a light on research activities within the context of the overall institutional enterprise over time. You will come away with a general understanding of an institution’s financials and how to broaden your own scope of awareness about higher ed R&D. SRECNP pronounced shrek – nep, we’ll have a little fun but it’s not Shrek and donkey.https://cassyni-user-files-prod.s3.amazonaws.com/SZGkyosGpEdA6twjW6qYpn https://cassyni.com/slides/outline/FtKK38QLtRhoetXrEMPTed https://cassyni.com/events/FtKK38QLtRhoetXrEMPTed/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JTG4gyACEpQw8gM9CSKTCz https://cassyni.com/events/FtKK38QLtRhoetXrEMPTed?videoPreview=1 Combined Heat and Power for Enhancing Energy Efficiency and Economic Developmentnohttps://cassyni.com/events/FtKK38QLtRhoetXrEMPTed?videoPreview=12013-12-12T09:00:00+00:002176.04 School of Public PolicyCombined heat and power (CHP) presents a significant opportunity for enhancing energy efficiency and economic development, particularly in the industrially intensive Southeastern United States. Despite its cost-effectiveness, CHP adoption remains limited, largely due to policy and utility revenue structures that disincentivize investment when utilities do not own the generating assets. A case study of a pulp paper plant in Columbus, Mississippi, illustrates successful CHP implementation where excess power generated from waste biomass is sold back to the Tennessee Valley Authority (TVA), demonstrating practical pathways for CHP integration. Economic analysis using an input-output approach reveals that CHP investment and operation generate substantial employment benefits, with construction and installation creating approximately 14 jobs per million dollars spent and operation and maintenance yielding nearly 20 jobs per million dollars. These figures surpass job creation associated with increased expenditures on natural gas, electricity, or fossil fuels. Beyond direct employment, CHP’s primary economic advantage lies in its capacity to reduce electricity prices through demand reduction-induced price effects, thereby lowering costs across residential, commercial, and industrial sectors. This price reduction stimulates broader economic activity and job creation by increasing disposable income and consumption. The analysis underscores CHP’s dual role as a driver of both energy efficiency and economic growth, highlighting the need for policy reforms to align utility incentives with CHP deployment and maximize its systemic benefits.https://cassyni-user-files-prod.s3.amazonaws.com/JTG4gyACEpQw8gM9CSKTCz https://cassyni.com/slides/outline/4XBS4NQBa1ZNcb5GudZypy https://cassyni.com/events/4XBS4NQBa1ZNcb5GudZypy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WfprtiuMJb5jJ6CV6U7wtz https://cassyni.com/events/4XBS4NQBa1ZNcb5GudZypy?videoPreview=1 Molecules at Work: On-surface Chemistry for high performance Functional Systems and Cooperative Molecular Machinesnohttps://cassyni.com/events/4XBS4NQBa1ZNcb5GudZypy?videoPreview=12026-05-20T07:10:00+00:002719.32Connecting Science, Publishing, and InnovationOn-surface precision chemistry performed with low-temperature STM and AFM under ultra-high vacuum conditions allows to develop unique chemical reaction schemes such as orthogonal- and surface catalyzed reactions with are not achievable with conventional liquid- or gas phase reactions. Beyond a number of useful on-surface reactions including polymer formation we found a fascinating new and powerful route of on-surface chemistry which allows us to set up a novel strategy for the generation of intelligent functional systems. To this end, we introduced a molecular swarm like system performing a coordinated surface restructuring based on N‐heterocyclic carbenes (NHC). Depending on the type of their N-ligands, NHCs the are essentially immobilized vertically by a single surface atom, forming, for example, unidirectional rotators, or are able to fully pull a single atom out of the surface and then travel on this newly formed ad-atom in the so-called ‘ballbot’- motion type across the surface, eventually forming densely packed islands. The molecular ballbots form spontaneously on the surface after vacuum deposition. We discovered that on an Au(1x2) reconstructed surface ballbot-NHCs can autonomously re-organize the surface atom by atom in a ‘swarm-like’ manor. These results open new perspectives on nano-mechanical mechanisms.https://cassyni-user-files-prod.s3.amazonaws.com/WfprtiuMJb5jJ6CV6U7wtz https://cassyni.com/slides/outline/AwqGaHw6VrAnFnpWDsgTvV https://cassyni.com/events/AwqGaHw6VrAnFnpWDsgTvV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PRgNgjnCS3fL3nhJ3M3Xne https://cassyni.com/events/AwqGaHw6VrAnFnpWDsgTvV?videoPreview=1 An Analysis of Unit-Price Procurement & Cooperative Purchasingnohttps://cassyni.com/events/AwqGaHw6VrAnFnpWDsgTvV?videoPreview=12023-05-31T08:00:00+00:002853.76 School of Public PolicyNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/PRgNgjnCS3fL3nhJ3M3Xne https://cassyni.com/slides/outline/MKUafH317pivvmp3XYZoEd https://cassyni.com/events/MKUafH317pivvmp3XYZoEd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CqSazF668rTft4qM5nu4yL https://cassyni.com/events/MKUafH317pivvmp3XYZoEd?videoPreview=1 Bridging the Gap: Integrating Basic Science and Clinical Decision-Making in Medical Educationnohttps://cassyni.com/events/MKUafH317pivvmp3XYZoEd?videoPreview=12025-04-23T08:00:00+00:003555.48AAMCThis webinar explores the challenge of integrating basic science and clinical medicine to enhance cognitive integration in medical learners. The session will present lessons learned from the development of the Aquifer Sciences Initiative, a national effort that unites basic scientists and clinicians to create a clinically relevant basic science curriculum. Participants will gain insights into how conceptual frameworks and structured, integrated learning objectives can bridge the gap between foundational sciences and clinical reasoning. The session will also highlight tools and strategies for faculty to support students in justifying clinical decisions through a strong basic science foundation. Learning Objectives: Describe the challenges of cognitive integration in medical education and the necessity of aligning basic science with clinical decision-making. Explain the development and implementation of the Aquifer Sciences Initiative as a framework for integrating basic science concepts into clinical education. Apply strategies for fostering cognitive integration in curriculum design to improve student engagement and clinical reasoning. This webinar is part of the Building Better Curriculum Series, hosted by the AAMC. For more information on the complete series, see the [series webpage](https://www.aamc.org/about-us/mission-areas/medical-education/curriculum-resources/establish-your-ci/webinars).  https://cassyni-user-files-prod.s3.amazonaws.com/CqSazF668rTft4qM5nu4yL https://cassyni.com/slides/outline/HrwMLVWL3crHu5WUstBqho https://cassyni.com/events/HrwMLVWL3crHu5WUstBqho/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GTq7u6QouYKGrtQZcCxNqc https://cassyni.com/events/HrwMLVWL3crHu5WUstBqho?videoPreview=1 Dispersion and cluster waves in periodic medianohttps://cassyni.com/events/HrwMLVWL3crHu5WUstBqho?videoPreview=12025-06-16T23:00:00+00:001231.6ETOPIMWe study the propagation of time-harmonic waves governed by the Helmholtz equation in an infinite medium containing a periodic array of small inclusions of arbitrary shape with Dirichlet or transmission conditions at their interfaces. The inclusion size a is much smaller than the array period, and the wavelength is fixed. We show that the character of wave propagation depends on whether the Bloch vector k is simple or its multiplicity is greater than one. In both cases, the perturbation to the solution is proportional to the size of the inclusion. However, the character of the solution and its dispersion are completely different.https://cassyni-user-files-prod.s3.amazonaws.com/GTq7u6QouYKGrtQZcCxNqc https://cassyni.com/slides/outline/Qmnq52Say9CAsdQQ8aTnEy https://cassyni.com/events/Qmnq52Say9CAsdQQ8aTnEy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6e75a6Lo7VKJ6qGFMVE7eW https://cassyni.com/events/Qmnq52Say9CAsdQQ8aTnEy?videoPreview=1 Kidney Talks - CKD how early is too early?nohttps://cassyni.com/events/Qmnq52Say9CAsdQQ8aTnEy?videoPreview=12026-06-10T12:00:00+00:001640.36Education for Primary Care Health Care ProfessionalsEarly CKD Why does it matter? How to approach screening and diagnosis? What can we do to reduce progression at this early stage?https://cassyni-user-files-prod.s3.amazonaws.com/6e75a6Lo7VKJ6qGFMVE7eW https://cassyni.com/slides/outline/LLBNZujxEucnG1z3Ra6URj https://cassyni.com/events/LLBNZujxEucnG1z3Ra6URj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/U5aBjZQhd9Pa3sh2qg6pei https://cassyni.com/events/LLBNZujxEucnG1z3Ra6URj?videoPreview=1 Promising Approaches in Higher Educationnohttps://cassyni.com/events/LLBNZujxEucnG1z3Ra6URj?videoPreview=12022-01-06T09:00:00+00:001198.88 School of Public PolicyThis seminar addresses the critical issue of underrepresentation of minority groups, particularly Black women, in STEM fields and higher education leadership. Drawing on data from the National Science Foundation and other sources, the analysis highlights persistent disparities in representation and degree attainment across Science, Technology, Engineering, and Mathematics disciplines. The discussion emphasizes that broadening participation is not merely a problem but a strategic imperative to advance scientific research, innovation, and educational outcomes. Key barriers to diversity are identified as psychological, social, and economic, necessitating evidence-based interventions to promote recruitment, persistence, and career advancement in STEM. Leadership development emerges as a pivotal factor, with a focus on inclusive leadership principles such as passion, knowledge, courage, advocacy, collaboration, transparency, and ethical decision-making. The speaker’s personal trajectory from economist to academic leader illustrates the importance of mentorship, sponsorship, and intentional leadership cultivation. Institutional initiatives at Georgia Tech, including executive leadership programs and inclusive leadership academies, exemplify efforts to foster leadership skills among faculty, staff, and students. The integration of diversity, equity, and inclusion (DEI) principles is underscored as essential for robust innovation and institutional success. The seminar concludes by advocating for bold leadership actions and scalable strategies to sustain diversity, equity, and inclusion, thereby enabling meaningful progress toward equitable representation and excellence in higher education and STEM fields.https://cassyni-user-files-prod.s3.amazonaws.com/U5aBjZQhd9Pa3sh2qg6pei https://cassyni.com/events/UjCeMXjshh2mRMLWVRRXed/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VAYsSbxK1zVK6gMLiUswAW https://cassyni.com/events/UjCeMXjshh2mRMLWVRRXed?videoPreview=1 Law and Data Driven Innovationnohttps://cassyni.com/events/UjCeMXjshh2mRMLWVRRXed?videoPreview=12019-11-16T09:00:00+00:002961.8 School of Public PolicyAbstract not yet added.https://cassyni-user-files-prod.s3.amazonaws.com/VAYsSbxK1zVK6gMLiUswAW https://cassyni.com/slides/outline/6W2TGmdFx67JcqXLWtk4gu https://cassyni.com/events/6W2TGmdFx67JcqXLWtk4gu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XGJgtWTHtBqjCsrZt1uAyk https://cassyni.com/events/6W2TGmdFx67JcqXLWtk4gu?videoPreview=1 In Conversation with Susan Cozzensnohttps://cassyni.com/events/6W2TGmdFx67JcqXLWtk4gu?videoPreview=12022-12-19T09:00:00+00:003687.24 School of Public PolicyThis seminar explores the intricate relationship between science, technology, and innovation (STI) policies and social inequality, drawing on extensive empirical and conceptual work. The discussion traces the evolution of research on innovation systems from a focus on university-industry relations and public research institutions in the early 1990s to a broader global perspective addressing inequality and inclusion. Key insights emerge from longitudinal studies and collaborative projects involving diverse international graduate students, which highlight the importance of tailoring innovation policies to local capabilities and addressing different segments of the income distribution—particularly the middle and lower ends—to foster more equitable economic development. The analysis distinguishes between vertical inequalities (rich-poor divides) and horizontal inequalities (disparities among culturally defined groups), emphasizing the need for nuanced policy approaches. The seminar critically examines the conceptual ambiguity surrounding terms like “social innovation” and “inclusive innovation,” advocating for clearer analytical frameworks to better understand and operationalize these concepts in STI policy. Case studies from global South contexts underscore the limitations of top-down diffusion models and the significance of bottom-up, problem-solving innovation processes rooted in local knowledge and informal sectors. While acknowledging the complexity and uncertainty posed by contemporary global challenges—including pandemics, energy crises, and climate change—the discussion maintains cautious optimism about the potential of STI policies to reduce inequalities through inclusive, context-sensitive strategies that empower marginalized populations and promote sustainable development.https://cassyni-user-files-prod.s3.amazonaws.com/XGJgtWTHtBqjCsrZt1uAyk https://cassyni.com/events/RGU4ELbzoxfzhPyktXC5eM/seminar/qa https://cassyni.com/slides/outline/RGU4ELbzoxfzhPyktXC5eM https://cassyni.com/events/RGU4ELbzoxfzhPyktXC5eM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/SXCKZperBWpFUVYC4JMVV8 https://cassyni.com/events/RGU4ELbzoxfzhPyktXC5eM?videoPreview=1 Reflections on Rangelands and Pastoralists in the Arabian Peninsulanohttps://cassyni.com/events/RGU4ELbzoxfzhPyktXC5eM?videoPreview=12026-05-27T07:00:00+00:001727.64Cambridge PrismsA discussion between Dr David Eldridge, co-Editor-in-Chief of Cambridge Prisms: Drylands and Dr Jonathan Davies, Agricultural Economics & Ecology Consultant. The questions discussed will include: The general view among practitioners and rangeland managers is that the Arabian Peninsula is extremely degraded, largely due to overgrazing by camels and goats. Is this view consistent with your understanding of these rangelands? Are there cost effective options to rehabilitate some of these degraded rangeland? Clearly, there are also likely to be co-benefits of rehabilitating degraded rangelands. Could you talk a little bit about these? There is considerable discussion among different rangeland agencies and NGOs about reinstating traditional pastoral systems such as al hima to restore rangelands and traditional lifestyles, but a lot has changed since these systems flourished. Do you think that there are elements of al hima that we could adopt in our current rangeland management practices? Perhaps tell us a little about al hima for those who aren’t familiar with these systems. How important is governance for establishing successful rangeland management practices in the Arabian Peninsula?https://cassyni-user-files-prod.s3.amazonaws.com/SXCKZperBWpFUVYC4JMVV8 https://cassyni.com/events/ZYQowA1ZWaHDjozWR34xm/seminar/qa https://cassyni.com/slides/outline/ZYQowA1ZWaHDjozWR34xm https://cassyni.com/events/ZYQowA1ZWaHDjozWR34xm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/82puSL6jz3xS4rsa1f3Wxe https://cassyni.com/events/ZYQowA1ZWaHDjozWR34xm?videoPreview=1 The Hero’s Journey: How epithelia contain viral spread via cell autonomous and collective mechanismsnohttps://cassyni.com/events/ZYQowA1ZWaHDjozWR34xm?videoPreview=12025-11-10T15:00:00+00:004362.88Night Science InstituteScience is done by people, not robots. As such, what we choose to study, and how we go about studying it is determined by our very human quirks and characteristics. Whether we like it or not, our emotions probably play the biggest role in motivating action. Wonder, curiosity, and awe inspire energy, playfulness, and focus; whereas frustration can drive us to quit or play it safe. In this talk, I'll introduce the idea that a scientific journey can be metaphorically viewed as the mythological Hero's Quest. To do so, I'll share several vignettes from our lab, focusing on how epithelial tissues restrict the spread of viruses using both cell autonomous and collective mechanisms. From each of these stories, one can appreciate that science cannot be done without trials and tribulations, emotional turmoil, creative frustration, and creative triumph. By conceptualizing scientific projects as myths, we gain perspective and tap into generational wisdom that emboldens us to take risks and be creative in investigating the natural world. https://cassyni-user-files-prod.s3.amazonaws.com/82puSL6jz3xS4rsa1f3Wxe https://cassyni.com/slides/outline/DukWy2L8XxR97R3oUmbo6u https://cassyni.com/events/DukWy2L8XxR97R3oUmbo6u/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Xvmo7bCTXVZsj6sizWuX3c https://cassyni.com/events/DukWy2L8XxR97R3oUmbo6u?videoPreview=1 Neoclassical transport in strong gradient regions in tokamaksnohttps://cassyni.com/events/DukWy2L8XxR97R3oUmbo6u?videoPreview=12024-04-04T06:00:00+00:002968.8Journal of Plasma PhysicsTheoretical descriptions of neoclassical transport in tokamaks are usually restricted to the core where the profiles of density, temperature, and radial electric field are relatively flat, compared to those in transport barriers. For example, in the pedestal, density and temperature can fall off on very short length scales and as a result a deep well forms in the profile of the radial electric field. In transport barriers, the gradient scale lengths can be of the order of the ion poloidal gyro radius. If standard, ”weak gradient”, neoclassical theory is applied to understand the properties of transport barriers, important strong gradient modifications to transport and other neoclassical quantities such as the bootstrap current are missed. Using a large aspect ratio and low collisionality expansion, we can capture gradient length scales as small as the ion poloidal gyro radius and calculate these strong gradient effects. One such effect is the poloidal variation in the electric potential, which contributes to trapping and causes transport modifications. We present a model describing the neoclassical transport of particles, momentum and energy for ions and electrons including strong gradients in the banana regime. We study the changes in the transport and the bootstrap current for some example pedestal profiles. The modifications show nonlinear dependence on the gradient strength and can enhance or decrease transport in comparison to the weak gradient neoclassical predictions.https://cassyni-user-files-prod.s3.amazonaws.com/Xvmo7bCTXVZsj6sizWuX3c https://cassyni.com/slides/outline/GNzYCSZkjFBdUMXN2TWRpq https://cassyni.com/events/GNzYCSZkjFBdUMXN2TWRpq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/81PudxRytdscmHcm2CqQEa https://cassyni.com/events/GNzYCSZkjFBdUMXN2TWRpq?videoPreview=1 The role of large-scale plasma turbulence in influencing particle transport and energization in astrophysical contextsnohttps://cassyni.com/events/GNzYCSZkjFBdUMXN2TWRpq?videoPreview=12023-10-05T06:00:00+00:002973.68Journal of Plasma PhysicsPopulations of energetic particles, ranging from solar energetic particles to incredibly high-energy cosmic rays, are ubiquitous in space and astrophysical plasmas. Several intertwined phenomena, including shocks, magnetic reconnection, and turbulence, are responsible for the efficient acceleration of particles and for determining their transport properties for efficient particle energization. Plasma turbulence produces patchy coherent structures, such as reconnecting current sheets, plasmoids, and vortices across a vast range of spatial scales. Under some circumstances, these structures can entrap particles, thus providing fast energization through, for example, drift acceleration. In this talk, I will review some of these mechanisms and outline recent numerical efforts aimed at investigating how the large-scale complexity of the turbulent magnetic field influences particle transport and how large-scale coherent structures impact particle energization. I will also comment on the applicability of these results in space and astrophysical contexts.https://cassyni-user-files-prod.s3.amazonaws.com/81PudxRytdscmHcm2CqQEa https://cassyni.com/slides/outline/BSWVjc6WLfec5Fp21yoS6h https://cassyni.com/events/BSWVjc6WLfec5Fp21yoS6h/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2naKZy8RKzJs9ahnC2khh8 https://cassyni.com/events/BSWVjc6WLfec5Fp21yoS6h?videoPreview=1 Biophysics in Africa: Latest cryo-EM results from South Africanohttps://cassyni.com/events/BSWVjc6WLfec5Fp21yoS6h?videoPreview=12023-11-29T06:00:00+00:004330.8Springer Nature Physics CommunityThe Electron Microscope Unit (EMU) at the University of Cape Town was established over sixty years ago as a regional imaging core facility serving the needs of the biological and materials science communities. Researchers in the EMU, with help from international scientists, have established the first single-particle cryo-EM resource in Africa. We support projects ranging from synthetic biology and biotechnology, to the metabolism of disease-causing organisms, vaccine-design, and structural characterisation of important human drug targets. We enable our users to competitively access international imaging facilities to collect high-resolution images by providing the necessary preliminary data and science cases. We have performed several high-resolution data collections every year since 2018 and have several years’ experience of generating samples, operating these microscopes and analysing the resulting datasets. In this talk, I will show some of the results of these efforts.https://cassyni-user-files-prod.s3.amazonaws.com/2naKZy8RKzJs9ahnC2khh8 https://cassyni.com/slides/outline/RmLeC4NcUJdxDRcJbhmsXB https://cassyni.com/events/RmLeC4NcUJdxDRcJbhmsXB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5Xm8ETwKXyfcRYvnodogYn https://cassyni.com/events/RmLeC4NcUJdxDRcJbhmsXB?videoPreview=1 The Mature Mind: Aging Resilientlynohttps://cassyni.com/events/RmLeC4NcUJdxDRcJbhmsXB?videoPreview=12023-05-17T08:00:00+00:003486.4Part of the nonprofit Annual Reviews organizationEveryone has a different idea of what it means to age well. Some people place the highest value on independent living, while others want to stay as close as possible to family and friends. One thing we all share is a desire to maintain our mental health and sharpness, but it can be difficult to know which actions — exercise, brain games, diet — to pursue with confidence as we get older. What is clear is that attitudes toward aging matter, and the earlier we start thinking seriously about how we want to navigate our own aging process and taking steps to achieve our goals, the better. On Wednesday, May 17, join AARP’s Vijeth Iyengar and bioethicist Tia Powell to discuss how different areas of the brain and mental abilities change over time, the role of neuroplasticity and learning in healthy aging, and what we all need to know about neurodegenerative conditions like Alzheimer’s disease, including caring for people with dementia. This is a conversation for anyone keen to push back against ageism and take care of their brains for the long haul. This event is the third in a series of events and articles exploring the brain across the lifespan. “Inside the brain: A lifetime of change,” is supported by a grant from the [Dana Foundation](https://dana.org/).https://cassyni-user-files-prod.s3.amazonaws.com/5Xm8ETwKXyfcRYvnodogYn https://cassyni.com/events/8URWf6c9tPqcHkQpWuWQg5/seminar/qa https://cassyni.com/slides/outline/8URWf6c9tPqcHkQpWuWQg5 https://cassyni.com/events/8URWf6c9tPqcHkQpWuWQg5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6ErLa6pukSFMyHoYwz571Q https://cassyni.com/events/8URWf6c9tPqcHkQpWuWQg5?videoPreview=1 On the Conceptual Limits of Standard Deontic Logicnohttps://cassyni.com/events/8URWf6c9tPqcHkQpWuWQg5?videoPreview=12026-05-27T14:00:00+00:005053.04Logica UniversalisDeontic logic aims to formulate moral concepts consisting of obligation, permission, and prohibition. Although the standard system of deontic logic (SDL) has long provided a fundamental framework for this kind of formalization, its application to non-ideal normative contexts continues to provide challenges. This paper provides a conceptual examination of SDL by analyzing its fundamental principles, semantic assumptions, and well-known paradoxes. The analysis emphasizes how moral conflicts and contrary-to-duty imperatives reveal structural tensions within conventional deontic frameworks, with a focus on classic paradoxes like the Chisholm and Ross paradoxes. The paper seeks to explain these challenges and demonstrate how they represent deeper conceptual constraints in modeling normative reasoning using idealized modal logics, rather than suggesting a new logical system. The main contribution of the paper is therefore clarificatory: it situates the limits of SDL in the context of larger philosophical discussions on moral conflict and normative consistency. https://cassyni-user-files-prod.s3.amazonaws.com/6ErLa6pukSFMyHoYwz571Q https://cassyni.com/events/14hSxquHJXY6XiDuxjtnE1/seminar/qa https://cassyni.com/slides/outline/14hSxquHJXY6XiDuxjtnE1 https://cassyni.com/events/14hSxquHJXY6XiDuxjtnE1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8ENfV1W6dCHsHPESXKcgmL https://cassyni.com/events/14hSxquHJXY6XiDuxjtnE1?videoPreview=1 Publishing at Nature Portfolio — An editorial view from Scientific Reports nohttps://cassyni.com/events/14hSxquHJXY6XiDuxjtnE1?videoPreview=12026-07-10T07:00:00+00:002496.04本次报告我们将从编辑的角度解读出版流程，提供稿件准备指导，并分享有效应对同行评审的策略。报告语言为普通话。 This interactive workshop provides scientists and researchers with an insider's perspective on academic publishing at *Scientific Reports*, Nature Portfolio. Drawing on extensive experience as a full-time scientific editor, the presentation will walk participants through the editorial lifecycle, from submission to decision, highlighting common pitfalls and strategies for success. Special attention will be given to structuring competitive research papers, responding effectively to reviewer feedback, and navigating ethical considerations such as authorship and data integrity. Designed for researchers at all career stages, this session aims to build confidence and competence in navigating the publishing landscape. Image credit: [Will Porada (Unsplash)](https://unsplash.com/photos/black-pen-on-notebook-y-6fm55D0nU).https://cassyni-user-files-prod.s3.amazonaws.com/8ENfV1W6dCHsHPESXKcgmL https://cassyni.com/events/MKJqyVwghfAa4DDUmyYUg5/seminar/qa https://cassyni.com/slides/outline/MKJqyVwghfAa4DDUmyYUg5 https://cassyni.com/events/MKJqyVwghfAa4DDUmyYUg5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/jF6oBzWv3YN3TSHdgAZdY https://cassyni.com/events/MKJqyVwghfAa4DDUmyYUg5?videoPreview=1 A Global One Health Dialogue on Headachesnohttps://cassyni.com/events/MKJqyVwghfAa4DDUmyYUg5?videoPreview=12026-09-10T13:00:00+00:003250.28The Journal of Headache and PainThis virtual webinar convenes two of the most influential leaders in headache medicine—the President of the European Headache Federation and the President of the International Headache Society—to explore how the global community can strengthen recognition, prioritisation, and management of migraine and other headache disorders. The discussion will address how professional societies are shaping strategic and operational frameworks to elevate migraine as a critical public health issue, including approaches to improving awareness, diagnosis, and care delivery across diverse healthcare systems. Speakers will offer insights into how coordinated models of care, policy engagement, and professional education can drive more consistent recognition of the burden associated with headache disorders worldwide. In addition, the session will examine the broader societal and global health implications of improving migraine care, including its potential contribution to advancing international development priorities. The conversation will highlight how strengthening advocacy, expanding access to care, and addressing unmet patient needs may translate into measurable progress in population health, productivity, and equity by the end of the decade. By combining expert perspectives with forward-looking strategies, this webinar will provide attendees with a deeper understanding of the role that leadership, collaboration, and innovation play in transforming headache care and positioning it within the wider global health agenda.https://cassyni-user-files-prod.s3.amazonaws.com/jF6oBzWv3YN3TSHdgAZdY https://cassyni.com/slides/outline/527GFMCa35Nh5SA2KarXdf https://cassyni.com/events/527GFMCa35Nh5SA2KarXdf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8cp9mjjMH68GYwnTuM5hjU https://cassyni.com/events/527GFMCa35Nh5SA2KarXdf?videoPreview=1 Keys to Successful Agingnohttps://cassyni.com/events/527GFMCa35Nh5SA2KarXdf?videoPreview=12021-05-06T06:00:00+00:003700.12Part of the nonprofit Annual Reviews organizationThe event will take the form of three one-to-one conversations covering practical aspects of successful aging; a framework that explains how we adapt to aging and the conditions under which we don’t; and an exploration of new treatments that hold the promise of reversing age-related cognitive impairments. The unique circumstances of the Covid-19 pandemic will form a backdrop to the discussion.https://cassyni-user-files-prod.s3.amazonaws.com/8cp9mjjMH68GYwnTuM5hjU https://cassyni.com/slides/outline/7VMHUmSCEN9BSNdasGmAMb https://cassyni.com/events/7VMHUmSCEN9BSNdasGmAMb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/MXDnfihFLSFtXQnuniruVY https://cassyni.com/events/7VMHUmSCEN9BSNdasGmAMb?videoPreview=1 Data-driven Machine Learning Models to Solve Complex Combustion Problemsnohttps://cassyni.com/events/7VMHUmSCEN9BSNdasGmAMb?videoPreview=12025-10-30T19:00:00+00:003482.44AI Institute in Dynamic SystemsThe Combustion Research Facility at Sandia National Laboratories is an internationally recognized leader in applied combustion research with unique expertise, laboratory, and computational facilities enabling development of the fundamental understanding needed to optimize new combustion technologies and adapt them to alternative fuels. In this seminar, recent activities performed at Sandia in collaboration with University of Washington and Universidade de Vigo and focused on using data-driven machine learning models to solve complex combustion-related problems will be discussed. Examples include prediction of fuel properties and optimization of fuel composition for aviation applications and according to user-defined merit functions. More specifically, the Fuel Optimizer, a modeling approach for evaluation, screening and design of synthetic aviation turbine fuels (SATFs) will be presented. The development of this tool was motivated by the interest of aviation industry in diversifying its fuel supply by increasing the use of SATF. Existing test methods for screening SATF are costly, time-consuming and require large amounts of fuel and, whereas simpler test and models exist, they lack predictive capability for fuel effects on engine performance. This is partly due to the complexity of almost intractable fuel-engine interactions for which machine learning models are suitable. Moreover, experimental databases collected through several decades of combustion research at Sandia and that are available for model training will be introduced for an open discussion about how these data can be combined with machine learning approaches to advance science beyond the current state of the art. https://cassyni-user-files-prod.s3.amazonaws.com/MXDnfihFLSFtXQnuniruVY https://cassyni.com/slides/outline/42p49yuXAAGYQgL2DcPCpm https://cassyni.com/events/42p49yuXAAGYQgL2DcPCpm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Ehpt3hY7TeTcGuFh1cg1wU https://cassyni.com/events/42p49yuXAAGYQgL2DcPCpm?videoPreview=1 Fluid-driven approaches for precision surface patterningnohttps://cassyni.com/events/42p49yuXAAGYQgL2DcPCpm?videoPreview=12024-01-26T06:00:00+00:00987.2Leeds Institute for Fluid DynamicsMicro/nano-patterned surfaces have found increasing applications in various emerging technologies thanks to their supreme functionalities related to wetting, self-cleaning, adhesion, acoustics and interactions with biological entities. Developing practical techniques to fabricate larger areas of such surfaces in a well-controlled and cost-effective manner, however, remains challenging. After a brief introduction to biomimetic engineering, this presentation will showcase examples of how natural inspirations can guide us to achieve functional design and sustainable manufacturing of scalable structured surfaces. I will discuss spontaneous yet predictable interfacial architectures generated through fluid-based methods that exploit thermodynamic phase change processes, namely condensation and crystallisation. Finally, I will demonstrate examples of the interfacial functionalities emerging from such surface structures.https://cassyni-user-files-prod.s3.amazonaws.com/Ehpt3hY7TeTcGuFh1cg1wU https://cassyni.com/slides/outline/Eu5MB294pET1vxA3q9ctmb https://cassyni.com/events/Eu5MB294pET1vxA3q9ctmb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Kt6UxwC1RHSGh9tbPgjHWE https://cassyni.com/events/Eu5MB294pET1vxA3q9ctmb?videoPreview=1 Publishing Your Paper: Insights for International Authorsnohttps://cassyni.com/events/Eu5MB294pET1vxA3q9ctmb?videoPreview=12025-06-10T08:00:00+00:003332.52NoneA panel discussion on best practices and tools for international authors planning to submit their manuscript to a scholarly journal. Sue Harris, PhD, managing editor of APA's flagship journal American Psychologist, shares author resources and moderates a panel discussion on best practices and tools for international authors planning to submit their manuscript to a scholarly journal, with a focus on APA-published journals. The goal is to not only share resources but also listen and learn about authors’ priorities and potential barriers to publishing. Image credit: [Kimberly Farmer (Unsplash)](https://unsplash.com/photos/shallow-focus-photography-of-books-lUaaKCUANVI).https://cassyni-user-files-prod.s3.amazonaws.com/Kt6UxwC1RHSGh9tbPgjHWE https://cassyni.com/slides/outline/SG1sMNY2K87n2tbpPotqhP https://cassyni.com/events/SG1sMNY2K87n2tbpPotqhP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FiWobF2PqKA9QwFBuVivJi https://cassyni.com/events/SG1sMNY2K87n2tbpPotqhP?videoPreview=1 Beyond Open Access: Building Justice in Scholarly Communicationnohttps://cassyni.com/events/SG1sMNY2K87n2tbpPotqhP?videoPreview=12026-01-13T15:45:00+00:001747.64Academic Publishing in EuropeIs Open Access sufficient? If we aspire to keep advancing scholarly communication, what should that future look like, who should shape it, and what will success look like? We must acknowledge the considerable work that brought scholarly communication to its current state, where Open Access appears to thrive – or not – depending one’s vista. The generations who championed Open Access never imagined it as an endpoint, or as having reached its maximum potential. Instead, it challenges us to imagine better, reach further, and push boundaries. Removing paywalls alone has not guaranteed equity. Questions of who controls scholarly infrastructure, linguistic diversity, cost distribution and how power flows throughout the system remain unresolved. True progress therefore requires us to address these structural factors directly. For this, justice must be the essential foundation of our ambition.https://cassyni-user-files-prod.s3.amazonaws.com/FiWobF2PqKA9QwFBuVivJi https://cassyni.com/slides/outline/SkfUQ4BYkafq2f8hzFBdxh https://cassyni.com/events/SkfUQ4BYkafq2f8hzFBdxh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/eTdFXsy3M975PdpLiMV74 https://cassyni.com/events/SkfUQ4BYkafq2f8hzFBdxh?videoPreview=1 Facing AI Futures Together: Using Scenarios to Rethink Libraries, Publishers, and the Scholarly Recordnohttps://cassyni.com/events/SkfUQ4BYkafq2f8hzFBdxh?videoPreview=12026-02-24T14:00:00+00:001781.12Researcher to ReaderArtificial intelligence (AI) is reshaping scholarly communication in unpredictable ways. Scenarios developed by the Association of Research Libraries and the Coalition for Networked Information highlight futures where discovery moves entirely to AI platforms, peer review is automated, or technology giants bypass traditional infrastructures. This session introduces those scenarios as a framework for understanding disruption across the research–to–reader lifecycle. It invites publishers, libraries, and researchers to consider how we might collaborate in preparing for multiple possible futures, protecting the scholarly record, and ensuring continued trust and value in an AI-driven world.https://cassyni-user-files-prod.s3.amazonaws.com/eTdFXsy3M975PdpLiMV74 https://cassyni.com/events/5WnVQfMystrWtu9Y7gyVos/seminar/qa https://cassyni.com/slides/outline/5WnVQfMystrWtu9Y7gyVos https://cassyni.com/events/5WnVQfMystrWtu9Y7gyVos/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CfmUZCHGNfjbfBWyyjzWea https://cassyni.com/events/5WnVQfMystrWtu9Y7gyVos?videoPreview=1 New Applications of Cardiac Computed Tomographynohttps://cassyni.com/events/5WnVQfMystrWtu9Y7gyVos?videoPreview=12025-12-02T03:00:00+00:004053.4The Auckland Bioengineering InstituteThe recent improvement of Cardiac Computed Tomography technology has yielded 3D images with 1mm^3 voxels collected within 150ms. This remarkable improvement in spatial and temporal resolution has enabled new clinical applications. In this seminar we will review developments of 4D CT (3D space and 1D time) for measuring LV function and dyssynchrony, LAA blood transport, and early detection of coronary calcium.https://cassyni-user-files-prod.s3.amazonaws.com/CfmUZCHGNfjbfBWyyjzWea https://cassyni.com/slides/outline/24FG5sqJogyssCqyU2bYH3 https://cassyni.com/events/24FG5sqJogyssCqyU2bYH3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KLng7rprYkv3L9Bsy6jRpz https://cassyni.com/events/24FG5sqJogyssCqyU2bYH3?videoPreview=1 AI – risk or opportunity? Preparing for the unexpectednohttps://cassyni.com/events/24FG5sqJogyssCqyU2bYH3?videoPreview=12025-11-04T20:00:00+00:003308.76Business SchoolAs artificial intelligence continues to evolve rapidly, New Zealand organisations must gain a clear understanding of both the risks and opportunities it presents. AI is increasingly recognised as an emerging threat with the potential to disrupt business operations, compromise data integrity, and challenge existing regulatory frameworks. To navigate this complex landscape, organisations need practical strategies to prepare for unexpected AI-related risks and build resilience across their operations. This includes implementing robust governance frameworks that promote responsible and accountable AI usage, ensuring ethical standards are upheld while maintaining transparency. Tools and techniques for scenario planning and incident response are essential to mitigate potential AI disruptions and safeguard continuity. At the same time, organisations must strike a careful balance between embracing innovation and managing risk, enabling long-term success in an AI-driven world without compromising security or trust. We will cover pragmatic approaches to monitor and track risk of AI operating in a dynamic commercial environment.https://cassyni-user-files-prod.s3.amazonaws.com/KLng7rprYkv3L9Bsy6jRpz https://cassyni.com/slides/outline/CvWZ6v4rTmAMPUg15ZqEDs https://cassyni.com/events/CvWZ6v4rTmAMPUg15ZqEDs/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6Agvs1rWDAyytyFYtDp8Ni https://cassyni.com/events/CvWZ6v4rTmAMPUg15ZqEDs?videoPreview=1 Implementing Clinical Competency Committees: Learning from the GME and UME experiencesnohttps://cassyni.com/events/CvWZ6v4rTmAMPUg15ZqEDs?videoPreview=12025-08-27T06:00:00+00:003645.44AAMCCompetency-based medical education (CBME) is an outcomes-based approach to training and assessing learners across the continuum of medical education. Core to this approach is a method for determining whether learners have met the threshold for advancement at specific stages of their training. Clinical competency committees (CCCs) are required for determining competency in ACGME-accredited graduate medical education (GME) programs in the U.S. However, there is no clear blueprint for implementing a CCC model in undergraduate medical education (UME). Interest in such a model is expanding following the recent publication of the AAMC’s Foundational Competencies and sentiment from the Undergraduate Medical Education to Graduation Medical Education Review Committee (UGRC). In this webinar, participants will learn about GME implementation of CCCs and link this with the experience of early adopters in UME. Presenters will share original research capturing several institutions’ implementation processes to incorporate the CCC model in medical schools. Lessons learned from the CCC experience across the continuum will be highlighted. This webinar is part of the Building Better Curriculum Series, hosted by the AAMC. For more information on the complete series, see the [series webpage](https://www.aamc.org/about-us/mission-areas/medical-education/curriculum-resources/establish-your-ci/webinars).  https://cassyni-user-files-prod.s3.amazonaws.com/6Agvs1rWDAyytyFYtDp8Ni https://cassyni.com/slides/outline/LL1dt8edpk4RPTPUg159sB https://cassyni.com/events/LL1dt8edpk4RPTPUg159sB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FEqwyLNFyAZBd4fpzaBZEn https://cassyni.com/events/LL1dt8edpk4RPTPUg159sB?videoPreview=1 Humanising Digital Technology: Not Mutually Exclusivenohttps://cassyni.com/events/LL1dt8edpk4RPTPUg159sB?videoPreview=12021-11-19T06:00:00+00:00930.04Business SchoolDigital Transformation is the adoption of digital technologies to transform services and businesses. This session brings about 2 excellent examples of digital transformation in New Zealand. https://cassyni-user-files-prod.s3.amazonaws.com/FEqwyLNFyAZBd4fpzaBZEn https://cassyni.com/slides/outline/ViainnaangvBtHN1F96y97 https://cassyni.com/events/ViainnaangvBtHN1F96y97/abstract https://cassyni-user-files-prod.s3.amazonaws.com/V5H79R5RaYJhhdnetSiSoQ https://cassyni.com/events/ViainnaangvBtHN1F96y97?videoPreview=1 Harnessing Enzymatic Power for Bioenergy and Therapeuticsnohttps://cassyni.com/events/ViainnaangvBtHN1F96y97?videoPreview=12025-12-12T09:00:00+00:003224.64Thieme India ChemTalksEnzymatic strategies for bioenergy and therapeutics are explored through two distinct research avenues. First, the integral membrane non-heme diiron enzyme UndB, responsible for hydrocarbon biosynthesis in *Pseudomonas* bacteria, was investigated. Characterization identified iron as the metal cofactor and elucidated a proposed mechanism involving β-hydrogen elimination as a rate-limiting step. Initial catalytic activity was limited by hydrogen peroxide production from uncoupled electron transfer. This limitation was overcome through co-expression with catalase, which increased total turnover numbers (TTN) from approximately 12 to 270, and further enhanced by a glucose dehydrogenase (GDH) system that extended enzyme activity to approximately 6 hours and improved TTN to 3400. Enzyme engineering also yielded variants with improved specificity for long-chain fatty acids, achieving approximately 3000 TTN for palmitic acid. A whole-cell biocatalyst developed using an UndB-catalase fusion construct achieved approximately 95% efficiency for 1-alkene production from lauric acid and approximately 70% for styrene, demonstrating superior performance compared to alternative enzymes. Second, the therapeutic potential of enzymes was investigated in combating biofilm-associated microbial infections. Polysaccharide-degrading enzymes, GH-B2 and CRhAB, were identified through bovine rumen metagenomics. GH-B2 demonstrated significant efficacy in dispersing *Klebsiella pneumoniae* biofilms at 5 µM within 2 hours, preventing biofilm formation, potentiating antibiotic efficacy *in vitro*, and accelerating wound healing *in vivo*. Similarly, CRhAB prevented *Acinetobacter baumannii* biofilm formation, and its immobilization onto medical gauze, combined with antibiotics, significantly reduced pathogen colonization and accelerated wound healing *in vivo*. Collectively, these findings highlight the significant potential of enzymatic approaches for sustainable bioenergy production and for developing novel anti-biofilm therapies against multidrug-resistant pathogens.https://cassyni-user-files-prod.s3.amazonaws.com/V5H79R5RaYJhhdnetSiSoQ https://cassyni.com/slides/outline/YBpk2CpCyyggFDqZnq1bs3 https://cassyni.com/events/YBpk2CpCyyggFDqZnq1bs3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DnxF3VHDbxat5hBPBFqM42 https://cassyni.com/events/YBpk2CpCyyggFDqZnq1bs3?videoPreview=1 Towards Predictive Gyrokinetic Simulations of Edge and SOL Turbulence in Reactor-Relevant Conditionsnohttps://cassyni.com/events/YBpk2CpCyyggFDqZnq1bs3?videoPreview=12026-01-22T16:00:00+00:002524.72Journal of Plasma PhysicsPredicting turbulent transport across the edge and scrape-off layer (SOL) is critical for the development of magnetic confinement fusion devices, including tokamaks and stellarators. However, first-principles full-f gyrokinetic (GK) simulations remain challenging due to complex magnetic geometries and their prohibitive computational cost. The high-performance full-f GK code GENE-X was specifically designed to overcome these challenges. Recently, a major computational acceleration was achieved through the implementation of a velocity-space spectral method, reducing the computational footprint by more than an order of magnitude. This breakthrough enables advanced first-principles studies of larger devices and high-confinement regimes, such as H-mode. Leveraging this new capability, we first present spectral simulations of L-mode plasmas in TCV. The new approach is validated through a detailed comparison with previously benchmarked grid-based simulations, showing excellent agreement in outboard midplane profiles, turbulence characteristics, and power balance. In this case, a computational speedup of nearly 50× is achieved. We then simulate the pre-L–H transition phase in AUG, focusing on a hydrogen discharge. As the L–H transition is approached, a region of strongly sheared radial electric field (Er) develops near the separatrix. Force-balance analysis reveals that the Er well is dominated by turbulence-driven poloidal flows. The turbulence is characterized by structures propagating in the electron diamagnetic direction, associated with electron drift waves and trapped-electron-mode turbulence. Notably, the predicted ion heat flux across the edge—a key quantity for L–H transition predictions—shows good quantitative agreement with experimental measurements. The role of turbulence-driven poloidal flows in shaping the Er well and their implications for H-mode access are further illustrated through comparisons of favorable and unfavorable configurations in AUG and TCV, validated against experiments. Overall, these results demonstrate that the spectral approach implemented in GENE-X provides a powerful and reliable first-principles predictive tool for turbulent transport studies in reactor-relevant scenarios, including ITER.https://cassyni-user-files-prod.s3.amazonaws.com/DnxF3VHDbxat5hBPBFqM42 https://cassyni.com/slides/outline/Qn6gKx7LQ7PAVBefEfPyQy https://cassyni.com/events/Qn6gKx7LQ7PAVBefEfPyQy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Ghp1gcKSiEGPS8bdqfyhgA https://cassyni.com/events/Qn6gKx7LQ7PAVBefEfPyQy?videoPreview=1 Science Publishing in Crisis: Challenges and Solutionsnohttps://cassyni.com/events/Qn6gKx7LQ7PAVBefEfPyQy?videoPreview=12026-01-14T14:30:00+00:005515.32Academic Publishing in EuropeScience relies on integrity and trustworthiness. But if disinformation and fake infiltrates the permanent scientific record of books and journals with the support of AI that even accelerates the fake, we have a fundamental problem in our “intellectual infrastructure”. It damages the scientific, medical and economic progress of our knowledge-based societies. Several factors drive the publishing crisis: on the one hand – the pull-factor – a reputation economy where scientists under career pressure in a “publish-or perish” culture too often behave unethically using shortcuts to reach their goals (promotion, salary raises, reputation) by purchasing AI-generated fake publications with plagiarism, fake data, text and images. This demand is satisfied by different “push-factors”: ‘paper mills’ offering fake-publications for sale, by predatory journals and conferences, fake reviews, and even some publishers that do not stop this fraud effectively. The results are manifold: a rising number of low-quality and several hundred thousand fake publications per year, editor and reviewer fatigue, misguided or irreproducible experiments, disinformation and escalating publishing costs that devour funding from taxpayers intended for research. Because it is high time to reform current publishing models to stop this unhealthy development, this session will present the consensus recommendations of an expert meeting held at the Royal Swedish Academy of Sciences in Stockholm in June 2025 and published in Royal Society Open Science (sciii-it.org/stockholm-declaration). A global plan was outlined with 34 action items within four topics: (i) Academia should resume control of publishing using non-profit publishing models (e.g. diamond open-access); (ii) Adjust incentive systems in academia to merit quality, not quantity, where the gaming of publication numbers and citation metrics distorts the perception of academic excellence; (iii) Implement mechanisms to prevent and detect fake publications and fraud which are independent of publishers; (iv) Draft and implement legislations, regulations and policies to increase publishing quality and integrity. This session brings together perspectives from academia and the publishing industry in a constructive dialogue on practical solutions. Dan Larhammar and Bernhard Sabel present the Stockholm Declaration’s recommendations. Steven Inchcoombe responds from a research publishing leadership perspective, outlining concrete industry initiatives against predatory publishers, paper mills, and enhanced quality control measures. All three speakers will have shared practical implementation proposals in advance to enable focused discussion. Format: Three 15-minute presentations followed by 45 minutes of moderated discussion on collaborative approaches to restore integrity in scholarly publishing.https://cassyni-user-files-prod.s3.amazonaws.com/Ghp1gcKSiEGPS8bdqfyhgA https://cassyni.com/events/ZNg8A4h9M1vMBDRkr1kQD/seminar/qa https://cassyni.com/slides/outline/ZNg8A4h9M1vMBDRkr1kQD https://cassyni.com/events/ZNg8A4h9M1vMBDRkr1kQD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DGAy6Cq721MwGZEJCFYYz2 https://cassyni.com/events/ZNg8A4h9M1vMBDRkr1kQD?videoPreview=1 Towards a Global Monitoring Framework of Soil and Rangeland Health: Building on 20 years of the LDSFnohttps://cassyni.com/events/ZNg8A4h9M1vMBDRkr1kQD?videoPreview=12026-09-07T15:00:00+00:002035.0Cambridge PrismsRangelands are among the most extensive land use systems globally, supporting the livelihoods of billions of people, sustaining pastoral economies, conserving biodiversity, and providing critical ecosystem services. Despite their importance, they remain among the least consistently monitored ecosystems. This lack of standardized, high quality data constrains the ability to assess degradation, evaluate restoration efforts, and report progress toward national and global targets. We conducted a review of existing rangeland monitoring frameworks, standards, and remote sensing platforms to understand the methodologies used and indicators measured. Results highlight significant fragmentation and inconsistency in current approaches, underscoring the urgent need for standardized monitoring systems that can capture the complexity and variability of rangeland ecosystems. The Land Degradation Surveillance Framework (LDSF) was developed in response to the need for systematic assessments of soil health, land degradation, and vegetation diversity within and across landscapes, including in rangelands. In this paper, we present the LDSF as a well-established, scalable approach for monitoring soil and land health, underpinning a globally harmonized rangeland monitoring system. Over the last two decades, the LDSF has been implemented in over 40 countries in the tropics and subtropics and has become an important database of georeferenced indicators of ecosystem health. In this paper we: (i) Report findings from a systematic review of existing rangeland monitoring frameworks, standards, and remote-sensing platforms; (ii) Synthesize the LDSF’s geospatially stratified, hierarchical sampling design and core indicator framework; and (iii) Demonstrate how LDSF field data and Earth Observation are combined to generate spatially explicit, statistically robust maps of soil and land health, including in African rangelands.https://cassyni-user-files-prod.s3.amazonaws.com/DGAy6Cq721MwGZEJCFYYz2 https://cassyni.com/events/8y6jpQmZjDKkqkjtiisUpD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LCRdUoJ7FMyZEB6yvUCAQW https://cassyni.com/events/Virww5jSpJBTLkkB8yt4E9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/M7KykAA9Z3iWh9kVxgxxm4 https://cassyni.com/events/PJTiSpqWWhuVfQk7ZeS6Ff/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CPhdaYn4brpHGd8Kni2sfc https://cassyni.com/events/GNggwWu1JGzds6rwtDBZt1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/G1yZ3kLxV6Ybj72zn5afcJ https://cassyni.com/slides/outline/JMJjEszzTU987HqaXjywwB https://cassyni.com/events/JMJjEszzTU987HqaXjywwB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NWWzm5zJDMN8Yc9Miu7grz https://cassyni.com/events/JMJjEszzTU987HqaXjywwB?videoPreview=1 The Bitter Lesson for the Bitter Lesson: The Role of Human Engineers in the Age of AInohttps://cassyni.com/events/JMJjEszzTU987HqaXjywwB?videoPreview=12026-02-12T19:30:00+00:004375.28AI Institute in Dynamic SystemsWith the ever increasing role of AI it is pertinent to ask the question: what will be the role of engineers and domain experts? In this talk we outline two approaches that incorporate the expertise of engineers into the latest techniques of AI and machine learning. First we showcase scientific machine learning, in particular universal differential equations, where machine learning architectures are mixed with traditional simulation techniques in order to discover higher order physical corrections and generate hypotheses for previously unknown governing laws. Then we dive into growing techniques for agentic AI in modeling and simulation, highlighting the recent empirical results around the tools and techniques which lead to improved accuracy of code generation in the context of nonlinear controls synthesis and analysis. Building on these results, we showcase the new Dyad platform for agentic AI which combines a new statically-analyzable acausal equation-based DAE modeling system with built-in scientific machine learning capabilities and demonstrate the real-world applications this is seeing in industrial applications from aerospace and automotive all the way to chemical process modeling. This talk will span the details from low level mathematical theorems to high level software demonstrations in applications, highlighting the elements of the new stack which have successfully translated into practice but also the areas which need further academic work to complete the transition.https://cassyni-user-files-prod.s3.amazonaws.com/NWWzm5zJDMN8Yc9Miu7grz https://cassyni.com/slides/outline/7V3SDqmSoPxBppPKmBpyBb https://cassyni.com/events/7V3SDqmSoPxBppPKmBpyBb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LNk61cqXrjzNN9BhuDup3p https://cassyni.com/events/7V3SDqmSoPxBppPKmBpyBb?videoPreview=1 How to review a journal article: An APA Journals webinar for Indonesian scholarsnohttps://cassyni.com/events/7V3SDqmSoPxBppPKmBpyBb?videoPreview=12026-03-06T03:00:00+00:003326.48None Image credit: [Glenn Carstens-Peters (Unsplash)](https://unsplash.com/photos/person-using-macbook-pro-npxXWgQ33ZQ).https://cassyni-user-files-prod.s3.amazonaws.com/LNk61cqXrjzNN9BhuDup3p https://cassyni.com/events/42WCu4EmjC5Yo85m7XT1em/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JprSvBdyX8EndctgUNaeDU https://cassyni.com/events/EtmVv6UKPGG2KPunj4ghbb/seminar/qa https://cassyni.com/slides/outline/EtmVv6UKPGG2KPunj4ghbb https://cassyni.com/events/EtmVv6UKPGG2KPunj4ghbb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TT2RjcJg6kVAB4bc7yZe7G https://cassyni.com/events/EtmVv6UKPGG2KPunj4ghbb?videoPreview=1 Characterising stormwater pollution from urban surfacesnohttps://cassyni.com/events/EtmVv6UKPGG2KPunj4ghbb?videoPreview=12026-03-06T01:15:00+00:002964.6Institute for Applied EcologyUrban stormwater is a key pathway for pollution entering aquatic environments, yet its composition and sources remain poorly resolved at fine scales. My PhD defines and investigates the characteristic pollutant signature in runoff from different pervious and impervious urban surfaces. By analysing runoff from different urban surface types, this research improves understanding of how surface type influences stormwater pollution. The results of this project will help inform more targeted and effective stormwater management strategies by highlighting key surfaces and processes, ultimately helping to reduce urban stormwater pollution and mitigate the ecological impacts of urban runoff on recelving waters.https://cassyni-user-files-prod.s3.amazonaws.com/TT2RjcJg6kVAB4bc7yZe7G https://cassyni.com/slides/outline/MosagJ3Yw2wXxgbmP5C5Nu https://cassyni.com/events/MosagJ3Yw2wXxgbmP5C5Nu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HwEsGEtnfX2Ph36mUxEYia https://cassyni.com/events/MosagJ3Yw2wXxgbmP5C5Nu?videoPreview=1 Making Scholarly Infrastructure AI-Ready (Lightning Talk)nohttps://cassyni.com/events/MosagJ3Yw2wXxgbmP5C5Nu?videoPreview=12026-02-25T09:00:00+00:00363.28Researcher to ReaderAI is reshaping scholarly communication, yet fragmentation is increasing complexity and cost. KnowledgeWorks Global Ltd. (KGL) explores how integrated, human-in-the-loop AI workflows—spanning research integrity, accessibility, and next-generation hosting platforms—can prepare trusted scholarly content for AI-driven discovery, licensing, and sustainable future revenue models.https://cassyni-user-files-prod.s3.amazonaws.com/HwEsGEtnfX2Ph36mUxEYia https://cassyni.com/slides/outline/QH7buiHB8Ki2Kd5Kvm6i6q https://cassyni.com/events/QH7buiHB8Ki2Kd5Kvm6i6q/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Do5hP4u1RTep8ieF8skTWn https://cassyni.com/events/QH7buiHB8Ki2Kd5Kvm6i6q?videoPreview=1 A3 – NSF HERD – Introduction to the Available Dataset and Possible Use Casesnohttps://cassyni.com/events/QH7buiHB8Ki2Kd5Kvm6i6q?videoPreview=12026-04-20T09:15:00+00:002494.48Research Analytics SummitThe NSF HERD survey is the only standardized publicly available dataset to assess research enterprise size and characteristics in the US. Due every January, the data are typically released in November – December later that year. This presentation will go over the NCSES data tool and discuss trends, analyses, and use cases your institution may be interested in with the available data. Learn about administrative basics like the history of the survey, what it collects, how to access data, what data are available, and in what formats. Explore use cases such as benchmarking, institutional strategy and goal – setting, and meaningful metrics that can be gleaned from the dataset. If you have suggested topics for us to discuss, please email hansa.magee@missouri.edu prior to April. This talk is meant for colleagues with little to no understanding and experience of the HERD survey and its outputs.https://cassyni-user-files-prod.s3.amazonaws.com/Do5hP4u1RTep8ieF8skTWn https://cassyni.com/slides/outline/GsPYDTaJYTQWZatRNbV5em https://cassyni.com/events/GsPYDTaJYTQWZatRNbV5em/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BT15QpaGLY2MC2VTia8xRk https://cassyni.com/events/GsPYDTaJYTQWZatRNbV5em?videoPreview=1 D1 – SCALE: A Data – Driven Framework for Building AI Readiness in Research Administrationnohttps://cassyni.com/events/GsPYDTaJYTQWZatRNbV5em?videoPreview=12026-04-20T13:30:00+00:002177.08Research Analytics SummitResearch offices increasingly recognize the need to strengthen their analytics capabilities and leverage AI – based tools to reduce administrative burden for faculty and staff; provide consistent, accurate and real – time guidance; and address the issue of scattered institutional knowledge. Without a clear roadmap connecting data, workflows, policies, and people, AI – implementation projects become difficult to evaluate, pilot or scale. This session introduces SCALE, a data – informed, human – centered framework designed to help research offices build the analytical and operational foundations required for responsible AI adoption. Unlike model – focused guidance, SCALE emphasizes the work with data and facilitates decision – making crucial for successful implementation. Participants will learn how to Scan landscape and process needs/gaps; Collect & Curate high – value data and scattered knowledge assets; Align & Architect solutions that integrate policies, workflows, and institutional priorities; Launch & Learn through iterative pilots and user engagement; and Evaluate & Expand using measurable indicators of value, adoption, and organizational impact. Using GrantsMate, an intelligent AI partner in research success, as an example, the session shows how SCALE structures institutional data, so AI and analytics can be applied consistently and responsibly, regardless of technology used. Attendees will learn how to advance research intelligence ecosystem, adopt AI, and make scalable decisions.https://cassyni-user-files-prod.s3.amazonaws.com/BT15QpaGLY2MC2VTia8xRk https://cassyni.com/slides/outline/Xgqfbxz3iC1rpCbntdxSWq https://cassyni.com/events/Xgqfbxz3iC1rpCbntdxSWq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TvFY2RDyVF8GdB8rY99bup https://cassyni.com/events/Xgqfbxz3iC1rpCbntdxSWq?videoPreview=1 I3 – from Manual Downloading to Automated Data Collection with APIs: A Practical Framework for Analystsnohttps://cassyni.com/events/Xgqfbxz3iC1rpCbntdxSWq?videoPreview=12026-04-21T13:30:00+00:002469.92Research Analytics SummitAs institutions increasingly rely on timely and accurate data, manual data collection methods can slow reporting and are inefficient and prone to human error. This session presents a practical, analyst – friendly framework for using APIs to automate data collection from both internal institutional platforms and public data sources. The session introduces API – based data pipelines and walks through the core steps of building an API workflow, including setup, reading vendor documentation, authentication, pagination, and integrating API data with internal tables. It also covers sustainable practices such as logging, data validation, documentation, and working effectively with IT partners. Two case studies—using Watermark course evaluation data and a public data source—show how the same API – based approach can be used to collect and integrate both internal and external datasets. By the end of the session, participants will be able to build automated API workflows, apply basic practices to support reliable and repeatable processes, and understand how automation can improve efficiency, data quality, and scalability, especially for small or understaffed analytics teams. Prerequisites: Basic Python knowledge; no advanced software or data engineering background required. Audience: Analysts, institutional research and research analytics teams, institutional leaders, and small teams without dedicated engineering support. Datasets Used: Watermark course evaluation data and public datasets such as IPEDS.https://cassyni-user-files-prod.s3.amazonaws.com/TvFY2RDyVF8GdB8rY99bup https://cassyni.com/slides/outline/SFi26SsGt9vnRLMZHixeXP https://cassyni.com/events/SFi26SsGt9vnRLMZHixeXP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3x6pwRGEtPqqWuDiNTZJAr https://cassyni.com/events/SFi26SsGt9vnRLMZHixeXP?videoPreview=1 Meta-Radiology • Imaging Exploration Lecture Series • Acoustic Bioeffects & Therapynohttps://cassyni.com/events/SFi26SsGt9vnRLMZHixeXP?videoPreview=12026-03-10T01:00:00+00:002838.72NoneTo provide a forum for the dissemination of new research findings in the field of radiology, the journal [Meta-Radiology(Metrad)](https://www.keaipublishing.com/en/journals/meta-radiology/) has Launched “Image Exploration Lecture Series” since 2024. The series regularly invites leading experts and active researchers to share their cutting-edge work. ♾️ Date: Mar. 10, 2026 ♾️ Speaker: Lili Niu ,Researcher Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences ♾️ Major Research: Ultrasound Brain-Computer Interface.Development of non-invasive neuromodulation technologies and systems based on ultrasound radiation force.Leveraging the non-invasive advantages of ultrasound to develop novel ultrasound neuromodulation systems and expand the clinical applications of medical ultrasound technology. https://cassyni-user-files-prod.s3.amazonaws.com/3x6pwRGEtPqqWuDiNTZJAr https://cassyni.com/slides/outline/23wQpxAZNintFebiMwfM73 https://cassyni.com/events/23wQpxAZNintFebiMwfM73/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Axq9TMn4nrACTgB32DshL2 https://cassyni.com/events/23wQpxAZNintFebiMwfM73?videoPreview=1 Energy flux decomposition in magnetohydrodynamic turbulencenohttps://cassyni.com/events/23wQpxAZNintFebiMwfM73?videoPreview=12026-04-02T15:00:00+00:002560.32Journal of Plasma PhysicsIn hydrodynamic (HD) turbulence, an exact decomposition of the energy flux across scales has been derived that identifies the contributions associated with vortex stretching and strain self-amplification to the energy flux across scales. Here, we extend this methodology to homogeneous magnetohydrodynamic (MHD) turbulence with both vanishing and strong mean magnetic field. Applied to data from direct numerical simulations, this decomposition allows for an identification of physical processes and for the quantification of their respective contributions to the energy cascade, as well as a quantitative assessment of their multi-scale nature through a further decomposition into single- and multi-scale terms. We find that vortex stretching is strongly depleted in MHD compared with HD, and the kinetic energy is transferred from large to small scales almost exclusively by the generation of regions of small-scale intense strain induced by the Lorentz force. In regions of large strain, current sheets are stretched by large-scale straining motion into regions of magnetic shear. This magnetic shear in turn drives extensional flows at smaller scales. Magnetic energy is transferred from large to small scales predominantly by the aforementioned current-sheet thinning in regions of high strain. This mechanism remains dominant in the strongly anisotropic regime. As a consequence of these results, we present a subgrid-scale turbulence model based on the dominant physical mechanisms that performs better compared to purely dissipative models. https://cassyni-user-files-prod.s3.amazonaws.com/Axq9TMn4nrACTgB32DshL2 https://cassyni.com/slides/outline/FPSj5QdjE5jr8ruJXAofmo https://cassyni.com/events/FPSj5QdjE5jr8ruJXAofmo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EwqhbLZEgT8j6b6qSB3XBL https://cassyni.com/events/FPSj5QdjE5jr8ruJXAofmo?videoPreview=1 Nonlinear MEMS Gas Sensors: Bridging Simulation and Experimental Validationnohttps://cassyni.com/events/FPSj5QdjE5jr8ruJXAofmo?videoPreview=12026-06-24T15:00:00+00:003253.2UK Microsystems NetworkMEMS gas sensors play a critical role in environmental monitoring, industrial safety, and healthcare due to their small size, low power consumption, and high sensitivity. This webinar presents a pathway from simulation to experimental validation of nonlinear MEMS resonant gas sensors. The design and numerical simulation of resonant structures are discussed, with an initial focus on single-bridge resonators to establish fundamental sensing principles. The discussion then extends to antisymmetric coupled resonators, showing how sensitivity can be significantly enhanced by exploiting nonlinear dynamic behaviour. Two sensing paradigms are examined, linear and nonlinear operation, highlighting their respective advantages and limitations. Particular emphasis is placed on operating near critical nonlinear phenomena, including buckling bifurcation and internal resonance, to amplify sensor response. Experimental results validate the proposed approaches and demonstrate the potential of nonlinear MEMS resonators for advanced gas sensing applications.https://cassyni-user-files-prod.s3.amazonaws.com/EwqhbLZEgT8j6b6qSB3XBL https://cassyni.com/slides/outline/2YcdzGKyDYGi57bEA3nKHF https://cassyni.com/events/2YcdzGKyDYGi57bEA3nKHF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7txYXQcqkGvH5D2DkW4Ezz https://cassyni.com/events/2YcdzGKyDYGi57bEA3nKHF?videoPreview=1 Building Your Scholarship Toolkit: Strategies for Getting Started in Research and Scholarshipnohttps://cassyni.com/events/2YcdzGKyDYGi57bEA3nKHF?videoPreview=12026-05-27T18:00:00+00:003708.76AAMCThis webinar is for anyone across academic medicine who is interested in contributing to research and scholarship—especially those who don’t typically identify as a “researcher” or “scholar” or who haven’t always had clear pathways or support to share their work. Staff and faculty are invited to hear from speakers from student affairs, educational affairs, and educational technology, who will share examples from their own careers and offer practical strategies for developing scholarly work and sharing it through presentations and publications. We hope you will come away from this webinar with a renewed perspective on the value of the work you do, plus concrete next steps you can apply to your own scholarly goals. This webinar is part of the Scholarly Publishing Webinar Series, hosted by Academic Medicine and MedEdPORTAL. For more information on the complete series, see [aamc.org/publishingwebinar](https://www.aamc.org/about-us/mission-areas/medical-education/scholarly-publishing-webinar-series).https://cassyni-user-files-prod.s3.amazonaws.com/7txYXQcqkGvH5D2DkW4Ezz https://cassyni.com/slides/outline/33GF2wyVezpm4t87kV57YZ https://cassyni.com/events/33GF2wyVezpm4t87kV57YZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NddBdcURkN8V8CAYX8Yi7x https://cassyni.com/events/33GF2wyVezpm4t87kV57YZ?videoPreview=1 Non-reciprocal Robotic Metamaterialsnohttps://cassyni.com/events/33GF2wyVezpm4t87kV57YZ?videoPreview=12026-07-01T14:00:00+00:002125.8UK Metamaterials NetworkRobotics promises to improve our lives by automating repetitive, delicate and dangerous tasks. Traditional robots have made huge strides towards these goals, but struggle with unpredictable environments and are ill-suited to miniaturization. By contrast, brainless organisms like starfish can squeeze through gaps and locomote over complex terrain by exploiting feedback between their soft bodies and the environment. In this talk I will argue that robotic metamaterials–architected lattices woven from many sensors and actuators–are a promising platform to capture such embodied intelligence. I will show that these machine materials can autonomously crawl, dig and walk without central control by collectively breaking reciprocal symmetries in their mechanical response. These materials may form the basis for smarter robot bodies that are robust, conformal and scalable. https://cassyni-user-files-prod.s3.amazonaws.com/NddBdcURkN8V8CAYX8Yi7x https://cassyni.com/slides/outline/9xLhgX2qoQaYZh7h7ve3hF https://cassyni.com/events/9xLhgX2qoQaYZh7h7ve3hF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/49TgevxJE9PiasMJcKDuF4 https://cassyni.com/events/9xLhgX2qoQaYZh7h7ve3hF?videoPreview=1 Validating benign termination as a reactor-relevant RE mitigation technique on the JET and DIII-D tokamaksnohttps://cassyni.com/events/9xLhgX2qoQaYZh7h7ve3hF?videoPreview=12026-05-14T15:00:00+00:002352.52Journal of Plasma PhysicsRunaway electrons (REs) produced during plasma disruptions remain a major unresolved risk for future high-current tokamaks, since their uncontrolled loss can severely damage plasma-facing components. A promising mitigation strategy is the benign termination scenario, where an global MHD event deconfines an already formed RE beam, spreading losses over a broad wall area and avoiding intense localized heat loads. This work presents a comprehensive cross-machine study of benign termination in the DIII-D and JET tokamaks, resolving discrepancies between medium-sized and larger devices and providing the first experimentally consistent theoretical framework for extrapolating benign termination physics to reactor-scale plasmas. In particular, previous JET experiments at high pre-disruptive plasma currents ($>2.5$ MA) posed challenges to achieve benign termination under reactor-relevant conditions. The analysis shows that these differences can be understood through a unified physics picture governed primarily by the internal inductance $l_i$, which characterizes the peaking of the RE current profile. The study identifies $l_i$ as the key parameter controlling both the character of the terminating MHD event and the edge safety factor at which termination occurs. Failed terminations in JET are linked to strongly peaked RE current profiles, which compress the beam to low edge safety factors and high RE densities, suppressing recombination. Magnetic analysis further shows that termination success correlates with the amplitude of the MHD perturbation rather than the instability growth rate, challenging previous ideal-MHD interpretations and emphasizing the importance of background resistivity. Linear CASTOR3D MHD modeling reproduces the observed stability boundaries: benign terminations in DIII-D are driven mainly by internal kink and coupled tearing modes, while JET is dominated by external kink modes. Kinetic modeling including neutrals shows that neutral injection, together with recombination, increases bulk resistivity. Nonlinear JOREK simulations demonstrate that this preferentially amplifies edge tearing modes, producing a more stochastic edge magnetic field during RE deconfinement and increasing the RE wetted area. The results identify resistivity, rather than free electron density, as the key parameter governing access to benign termination. Overall, this work provides the first broadly applicable and experimentally consistent description of the MHD mechanisms underlying the benign termination scenario, critical for extrapolation to next-step fusion devices.https://cassyni-user-files-prod.s3.amazonaws.com/49TgevxJE9PiasMJcKDuF4 https://cassyni.com/events/61BVRgNXh757vowFyDbmx9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/14X9CrW1T19D9zt4AbPJHk https://cassyni.com/events/AT1vqqCFeE4NPTh3ssNM6d/seminar/qa https://cassyni.com/slides/outline/AT1vqqCFeE4NPTh3ssNM6d https://cassyni.com/events/AT1vqqCFeE4NPTh3ssNM6d/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CdU22EcveDYLWC8hyu9SK8 https://cassyni.com/events/AT1vqqCFeE4NPTh3ssNM6d?videoPreview=1 Understanding and improving hygro-thermal durability of bio-based composites for structural applicationsnohttps://cassyni.com/events/AT1vqqCFeE4NPTh3ssNM6d?videoPreview=12026-06-17T10:15:00+00:001623.2NoneGlobal warming necessitates the development of bio-based materials, with natural fibre composites offering a carbon-negative solution for large-volume applications such as civil engineering structures. However, their hygro-thermal durability, particularly moisture sensitivity, remains a challenge. This research investigated the moisture aging, fatigue, and creep behaviour of natural fibre composites, alongside strategies to enhance their long-term performance. Experimental studies involved cyclic moisture loading, immersion testing, and outdoor exposure, often combined with mechanical fatigue and creep tests conducted in controlled climate chambers. Results indicate that composite stiffness decreases with increasing humidity, with the extent of reduction (e.g., up to 40% in poorly bonded systems) highly dependent on the matrix and fibre-matrix adhesion. Fatigue behaviour of natural fibre composites was comparable to glass fibre systems, with stiffness tending to stabilize or even increase over fatigue cycles, a distinct characteristic. Creep studies revealed that the secondary creep rate is predictive of failure time, and time-temperature superposition enabled lifetime predictions, with estimates reaching 142 years under specific conditions. Good fibre-matrix adhesion consistently limited creep, with plasma treatments demonstrating reduced creep strain. Durability improvement strategies explored include using lignin-rich fibres like bamboo to reduce water uptake, applying enzymatic treatments to lower water absorption and diffusion, and utilising pre-swollen fibres during manufacturing to mitigate initial swelling-induced damage and improve mechanical property retention during cyclic moisture exposure. While immersion testing typically showed property degradation, cyclic moisture tests sometimes revealed an initial property decrease followed by an improvement, termed "hornification." Overall, enhancing fibre-matrix adhesion and employing pre-swollen fibres show significant promise for improving durability. Future work will investigate barrier coatings to further prevent component leaching and improve long-term performance.https://cassyni-user-files-prod.s3.amazonaws.com/CdU22EcveDYLWC8hyu9SK8 https://cassyni.com/slides/outline/Uj2ufkeZHXUQYnjwjrQD65 https://cassyni.com/events/Uj2ufkeZHXUQYnjwjrQD65/abstract https://cassyni-user-files-prod.s3.amazonaws.com/J1uw8aKFKwAahHHnzKNk6i https://cassyni.com/events/Uj2ufkeZHXUQYnjwjrQD65?videoPreview=1 AEHS Forum Series 22nd •Exercise, Neuroprotection and Mental Healthnohttps://cassyni.com/events/Uj2ufkeZHXUQYnjwjrQD65?videoPreview=12026-06-18T01:00:00+00:003783.36NoneTo further boost academic exchanges and build a more dynamic and diversified academic communication platform, [Advanced Exercise and Health Science(AEHS)](https://www.keaipublishing.com/en/journals/advanced-exercise-and-health-science/) has decided to regularly launch the AEHS Online Forum starting from January 2024. AEHS welcomes experts and scholars to share the latest research findings and exchange academic insights on this platform.https://cassyni-user-files-prod.s3.amazonaws.com/J1uw8aKFKwAahHHnzKNk6i https://cassyni.com/slides/outline/6VriazXwXvYwkGvmmKik8M https://cassyni.com/events/6VriazXwXvYwkGvmmKik8M/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PexiiUy678wYehU4uFRRSv https://cassyni.com/events/6VriazXwXvYwkGvmmKik8M?videoPreview=1 Current sheet formation and steady-state reconnection under radiative coolingnohttps://cassyni.com/events/6VriazXwXvYwkGvmmKik8M?videoPreview=12026-09-10T15:00:00+00:002643.72Journal of Plasma Physics**This paper was selected as one of JPP's Featured Articles by a combined vote of our Editorial Board and Advisory Board. Please see [here](https://www.cambridge.org/core/journals/journal-of-plasma-physics/featured-articles) for more information.** Magnetic reconnection underpins some of the most significant energy transfer and conversion processes in magnetised plasmas; it plays a role in driving flaring events in astrophysical objects such as gamma ray bursts and AGN jets, mediates the interaction between black hole accretion disks and their coronae, and significantly contributes to the dynamics of many extreme environments such as pulsar wind nebulae and pulser magnetospheres. In most of these environments, radiative cooling also plays a central role in shaping the plasma dynamics, yet relatively little is known about the interaction between radiation and reconnection processes. The presented work aims to lay out the groundwork for a more complete theoretical understanding of reconnection in a regime dominated by optically thin radiative cooling by revisiting and extending the simple MHD model of current sheet formation through X-point collapse (Syrovastkii JETP 1971), by including a radiative cooling term in the equation of state. The results show that whilst radiative-cooling accelerates the collapse of the X-point along the direction of the inflows, strong cooling can arrest the current sheet elongation in the outflow direction and even result in its reversal and collapse along the outflow direction as well. Furthermore, in modifying the steady-state model developed by Uzdensky and McKinney (PoP 2011), it is found that when radiative cooling dominates over compressional heating, the current sheet length falls below the global system scale, accompanied by a reconnection rate that exceeds the classical Sweet–Parker prediction. https://cassyni-user-files-prod.s3.amazonaws.com/PexiiUy678wYehU4uFRRSv https://cassyni.com/events/GNpoWfUSK5dGbnvoGtV7GH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/L5GEDdPE8zqXovnCo5u2mc https://cassyni.com/events/9Tmxyivya2oafDjQWpzSzR/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4G1a4cS1DKXhbwfi9z1G46 https://cassyni.com/slides/outline/YC6yAVy51awwhhDjgfngx5 https://cassyni.com/events/YC6yAVy51awwhhDjgfngx5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Sg1ngvSqepPVrPvxTHLBfc https://cassyni.com/events/YC6yAVy51awwhhDjgfngx5?videoPreview=1 Promoting Parsimonious Priors for Planning, Projections, and Physicsnohttps://cassyni.com/events/YC6yAVy51awwhhDjgfngx5?videoPreview=12026-09-01T10:00:00+00:003319.28Department of AeronauticsModern machine learning relies on enormous datasets and computational resources to train complex black-box models. Science and engineering rarely have this luxury: high-quality samples are slow and expensive to obtain, and models must be interpretable and trustworthy. Dynamical systems, though, carry substantial underlying structure, and promoting that structure serves as an alternative to collecting more data. In this talk, I will discuss different approaches for searching for this structure, such as promoting sparsity for equation discovery and control (Zolman et al., 2025) and promoting symmetry to improve generalization and find intrinsic coordinates (Otto et al., 2025). In particular, I present recent work that searches for sensitivity structure in dynamical systems to construct useful low-dimensional representations (Zolman et al., 2026). Most dimensionality reduction methods, such as PCA/POD, are based on reconstruction losses that favor large energetic structures, but in the process they discard dynamically relevant structures that nonlinear instabilities amplify into rare and extreme events. By using gradient information from quantities of interest, I show how we can use the dominant sensitive subspace to identify mechanisms driving extreme events, build early-warning systems, and even develop intuitive controllers to completely prevent them.https://cassyni-user-files-prod.s3.amazonaws.com/Sg1ngvSqepPVrPvxTHLBfc https://cassyni.com/slides/outline/8VEZyMYrZrhgZihNYEzYaH https://cassyni.com/events/8VEZyMYrZrhgZihNYEzYaH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Vv5trcUEXijiMwDWw2HZt2 https://cassyni.com/events/8VEZyMYrZrhgZihNYEzYaH?videoPreview=1 Homogenization theory and neural field modelsnohttps://cassyni.com/events/8VEZyMYrZrhgZihNYEzYaH?videoPreview=12023-03-28T13:00:00+00:003825.12MetaMATIn the last decades great advances have been made in mapping neural circuitry of the brain. This has been facilitated by novel experimental techniques for studies both at the single-cell and systems levels. It still remains, though, to combine all the pieces in the puzzle to a coherent picture of brain function. While single nerve cells (neurons) are fairly well understood, the signal - processing properties of the nerve-cell networks in cortex are still obscure. The growth of experimental data has led to a revival of so - called rate equation models for cell networks in nervous tissue (neural networks). In these models, the probability for firing action potentials, the key information carriers in the brain, is the main dynamical variable. These models assume the form of coupled integral and integro - differential equations, and they describe non-linearand nonlocal interactions between the population of excitatory and inhibitory neurons. In the present talk I will discuss the properties of the continuum limit of a 2 population nonlocal Hopfield type of neuronal network model, with spatial periodic microstructure incorporated in the connectivity strength. The modelling framework is derived by means of a homogenization procedure, where the spatial nonlocalities are dealt with by means of Visintins theorem for 2-scale convergence of convolution integrals. I will discuss existence and stability of stationary localized solutions (bumps) and pattern formation though Turing type of instabilities within the framework of this model. https://cassyni-user-files-prod.s3.amazonaws.com/Vv5trcUEXijiMwDWw2HZt2 https://cassyni.com/events/8xxdFGC8iQh874g3L3ZwRw/seminar/qa https://cassyni.com/slides/outline/8xxdFGC8iQh874g3L3ZwRw https://cassyni.com/events/8xxdFGC8iQh874g3L3ZwRw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/V7c5BCHB5pW4vKXQwAEBPc https://cassyni.com/events/8xxdFGC8iQh874g3L3ZwRw?videoPreview=1 Biocompatible Materials Tribologynohttps://cassyni.com/events/8xxdFGC8iQh874g3L3ZwRw?videoPreview=12026-04-15T15:00:00+00:001648.044D Health Tech Network+ Silicone breast implants, particularly those with high-roughness macrotextured surfaces, are linked to complications ranging from localized tissue damage to Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL). To elucidate the mechanisms behind these adverse outcomes, recent studies utilized custom in vitro biomimetic models to evaluate the biotribology of both implant-tissue and implant-implant (shell-shell) sliding interactions. Findings reveal that surface texture, rather than elastic modulus, primarily dictates frictional shear stress and wear debris generation. During implant-tissue sliding, highly textured implants induced severe frictional shear stresses exceeding 100 Pa, leading to significant collagen degradation and epithelial cell rupture. Furthermore, cyclic shell-shell sliding of macrotextured implants generated substantially higher friction and yielded over ten times more silicone wear debris compared to smooth counterparts. When introduced to macrophages, this tribologically generated debris provoked widespread phagocytosis and a dose-dependent increase in pro-inflammatory cytokine secretion. Ultimately, these integrated findings establish a mechanistic link between macrotextured implants, non-physiological frictional forces, and chronic, macrophage-mediated inflammation, underscoring the critical need for smoother, lower-friction implant designs to mitigate post-implantation complications.https://cassyni-user-files-prod.s3.amazonaws.com/V7c5BCHB5pW4vKXQwAEBPc https://cassyni.com/slides/outline/AyCnB9BXEXZPTccvvQYmgH https://cassyni.com/events/AyCnB9BXEXZPTccvvQYmgH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4w8xoEaoKyvYJWF8kGBAhk https://cassyni.com/events/AyCnB9BXEXZPTccvvQYmgH?videoPreview=1 The Microbe's Master Plan to Control Sperm and Shape Generationsnohttps://cassyni.com/events/AyCnB9BXEXZPTccvvQYmgH?videoPreview=12024-11-12T14:00:00+00:001865.16Microbiome Virtual International ForumHalf of all animal species harbor bacteria and phages in the reproductive tissues, yet the extent to which these microbes influence host biology is often overlooked relative to the microbiomes of guts and roots, for instance. In this talk, I will illuminate (i) the most widespread bacterial symbiosis in the animal kingdom (Wolbachia reproductive symbionts and their phage WO) and (ii) the central dogma underpinnings by which they determine the fate of Drosophila sperm biology to create a symbiosis that is fundamental to host evolution and vector control. https://cassyni-user-files-prod.s3.amazonaws.com/4w8xoEaoKyvYJWF8kGBAhk https://cassyni.com/events/EtucVF3kQ4tf45ye7jzEys/seminar/qa https://cassyni.com/slides/outline/EtucVF3kQ4tf45ye7jzEys https://cassyni.com/events/EtucVF3kQ4tf45ye7jzEys/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Gb8PPpnkqDkRFyvdfem8Yn https://cassyni.com/events/EtucVF3kQ4tf45ye7jzEys?videoPreview=1 How to get published with the Nature Portfolionohttps://cassyni.com/events/EtucVF3kQ4tf45ye7jzEys?videoPreview=12026-08-26T14:00:00+00:003610.72Research Seminars by Springer NatureWe are pleased to invite early career researchers (ECRs) to a webinar exploring the key aspects of scientific publishing, with a particular focus on the standards and best practices of Nature Portfolio journals. The speakers are experienced editors of Nature-branded research and reviews journals. The webinar will provide an overview of the Nature Portfolio journal publishing landscape and will cover the editorial process, different content types, and peer review. We will also share practical guidance for preparing and submitting scientific manuscripts. The presentation will be followed by a live Q&A session, offering attendees the opportunity to have their questions answered by Nature Portfolio editors. This event is jointly organised by editors from the Nature Portfolio ECR Working Group and the Springer Nature Reviewer Engagement team.https://cassyni-user-files-prod.s3.amazonaws.com/Gb8PPpnkqDkRFyvdfem8Yn https://cassyni.com/events/43TNnTkuRTaFonSAXYEgwF/seminar/qa https://cassyni.com/slides/outline/43TNnTkuRTaFonSAXYEgwF https://cassyni.com/events/43TNnTkuRTaFonSAXYEgwF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AfFJFMCkW7UHPxCxUJu5HY https://cassyni.com/events/43TNnTkuRTaFonSAXYEgwF?videoPreview=1 Session 4: Control Systemsnohttps://cassyni.com/events/43TNnTkuRTaFonSAXYEgwF?videoPreview=12023-10-05T14:30:00+00:005458.72Brahmal Vasudevan Institute for Sustainable Aviation at Imperial College London**Chair: Eli Livne (University of Washington)**https://cassyni-user-files-prod.s3.amazonaws.com/AfFJFMCkW7UHPxCxUJu5HY https://cassyni.com/slides/outline/15ecrFRQzo2oYNaKNkgTWV https://cassyni.com/events/15ecrFRQzo2oYNaKNkgTWV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9wTL2HosqQri6tc19EofWv https://cassyni.com/events/15ecrFRQzo2oYNaKNkgTWV?videoPreview=1 3rd international Biometals webinarsnohttps://cassyni.com/events/15ecrFRQzo2oYNaKNkgTWV?videoPreview=12024-03-12T14:00:00+00:005289.08BioMetalsWelcome to the 3rd international webinars series. For those who don't already know, these webinars have been set up by the international Biometals society and the journal Biometals with the help of Cassyni platform. * The aim is to promote research in the field of metal interactions in biology and to encourage the interdisciplinary exchange of information at international level. Today we welcome two speakers: * Wolfgang Maret will be talking about zinc homeostasis, zinc containing zinc signaling and zinc in relation with human diseases. Zinc is a metallic element whose role has been underestimated for far too long...so affine and yet so discreet! So affine if we consider the irwing Williams series, but quite silent metal ions in term of spectroscopy (except using Xray absorption). X-ray structures reveal zinc in so many proteins, and mass spectrometry reveals it in so many biological environment. * The 2nd speaker, Isabelle Schalk was invited to pay tribute to Pierre Cornelis, who left us too early last december. Pierre was president of the international biometals society and associate editor due Biometals. We will miss him. As Pierre, Isabelle work focus on iron homeostasis in Pseudomonas.Iron is essential but may be scarce in some medium conditions such as infected host or environment. So, microorganisms develop tricks to be sure to get their required micromolar internal concentration. Isabelle will show some Pseudomonas tricks that involve iron uptake in complex with several siderophores In 1869, Jules Raulin, a student of Louis Pasteur working in Lyon (France), reported that zinc is essential for the mold Aspergillus niger. It took another 100 years until the late Ananda Prasad and his colleagues showed that zinc is an essential micronutrient for humans. In the last 80 years, roles of zinc as catalytic metal ion in an increasing number of enzymes and as a structural metal ion in proteins such as zinc fingers involved in protein-DNA, protein-RNA, and protein-protein interactions were revealed, culminating in bioinformatics investigations that estimated that at least 3000 human proteins are zinc proteins. In the last decades, additional modes of action emerged, namely that Zn2+ ions have a regulatory role akin to and complementary to Ca2+ ions in intracellular signalling and are secreted from vesicular stores as extracellular autocrine, paracrine, and possibly endocrine messengers. These signalling functions include additional targets that further increase the number of zinc-dependent proteins. The control of all these zinc-dependent processes requires a complex system of regulation. Minimally, it involves 24 zinc transporter proteins that increase or decrease cytosolic zinc concentrations, a dozen metallothioneins as dynamic metal buffers to modulate the availability of zinc at remarkably low concentrations, transcription factors serving as metal sensors, and a recently discovered metallochaperone for zinc. After focusing on the coordination dynamics of zinc in the chemical and biochemical mechanisms employed in this complex zinc homeostatic system and the important relationship between zinc metabolism and redox metabolism, I will briefly introduce our present work on some aspects of zinc in human disease (diabetes and inflammatory conditions of the skin, gut, and connective tissue). Pseudomonas aeruginosa, a ubiquitous bacterium found in diverse natural and man-made environments, serves as a pathogen for plants, animals, and humans. Like most living organisms, iron is indispensable for its growth. The bacterium has developed intricate systems, relying on the use of siderophores, to access iron and maintain homeostasis, crucial for survival in dynamic host environments. P. aeruginosa can produce two siderophores and utilize various siderophores from other bacteria. These iron uptake pathways predominantly rely on TonB-dependent transporters (TBDTs) for iron uptake across the outer membrane. Through proteomic and qRT-PCR analyses, we explored how P. aeruginosa modulates its iron import pathways in response to environmental cues. Additionally, fluorescent reporters fused with TBDT promoter regions enabled us to monitor TBDT expression under different growth conditions. Mathematical modeling revealed distinct transcription and expression profiles for various TBDTs. Our findings offer precise insights into how P. aeruginosa adjusts the expression of its iron-uptake pathways, demonstrating phenotypic plasticity mechanisms in response to varying iron levels and competition pressures.https://cassyni-user-files-prod.s3.amazonaws.com/9wTL2HosqQri6tc19EofWv https://cassyni.com/events/Poyd32TWSMBAar4eYbUhU9/seminar/qa https://cassyni.com/slides/outline/Poyd32TWSMBAar4eYbUhU9 https://cassyni.com/events/Poyd32TWSMBAar4eYbUhU9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/W3xgQAF24FzXPZFJWU1hkr https://cassyni.com/events/Poyd32TWSMBAar4eYbUhU9?videoPreview=1 Sexual and Reproductive Health Across Africa: Challenges and Opportunitiesnohttps://cassyni.com/events/Poyd32TWSMBAar4eYbUhU9?videoPreview=12024-07-18T13:00:00+00:003121.88Women's HealthSexual and reproductive health is critical for those of all genders at every stage of life. Across Africa, poor sexual and reproductive health compromises the wellbeing, economic status, and independence of families and individuals. Many challenges exist to attaining optimal sexual and reproductive health, ranging from those related to the need for more and better-trained healthcare providers, barriers to family planning, pregnancy complications, and access to comprehensive abortion care. Opportunities to improve sexual and reproductive health include enhancing the quality and delivery of patient services, promoting community access, evaluating evidence-based health policies, as well as reducing overall poor health outcomes and mortality. For this Special Collection, we are seeking high-quality original research and review articles that address three main topic areas of family planning and contraceptive services, comprehensive abortion care, and sexual and reproductive health and rights.https://cassyni-user-files-prod.s3.amazonaws.com/W3xgQAF24FzXPZFJWU1hkr https://cassyni.com/slides/outline/AwyP9SWXWeoQzUtMcYz1Jm https://cassyni.com/events/AwyP9SWXWeoQzUtMcYz1Jm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8Brbj4F7npwSa6yyTVMBh8 https://cassyni.com/events/AwyP9SWXWeoQzUtMcYz1Jm?videoPreview=1 Yoonie Han plays Saint-Saëns/Godowsky "The Swan"nohttps://cassyni.com/events/AwyP9SWXWeoQzUtMcYz1Jm?videoPreview=12020-11-15T12:00:00+00:00171.72Hong Kong Baptist UniversityYoonie Han's new album "Hollywood Romance" (2020) on Universal Music includes classical piano pieces from Hollywood's Golden Age Films. From Saint-Saëns’ Carnival of the Animals, Le Cygne (The Swan) reflects a pure and elegant swan swimming gracefully over a calm lake. ‘Quartet’ (2012) is a story about reconciliation and love through ups and downs while retired musicians preparing for a concert at a nursing home.https://cassyni-user-files-prod.s3.amazonaws.com/8Brbj4F7npwSa6yyTVMBh8 https://cassyni.com/slides/outline/MKAjQMNFgrXwKX9dPJEwHo https://cassyni.com/events/MKAjQMNFgrXwKX9dPJEwHo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JwXFR1U7QWJNx8gghKse22 https://cassyni.com/events/MKAjQMNFgrXwKX9dPJEwHo?videoPreview=1 Episode 3: George Lam's "The Emigrants" with New Morse Codenohttps://cassyni.com/events/MKAjQMNFgrXwKX9dPJEwHo?videoPreview=12020-08-24T12:00:00+00:004462.04Hong Kong Baptist UniversityOn the third episode of our Home Brew series, 5BMF celebrates the album release of “The Emigrants,” a new work by George Lam, performed by the fantastic cello and percussion duo New Morse Code. Composed for cello, percussion, and spoken voice, "The Emigrants" honors and celebrates the stories of seven musicians who set out from their homelands to settle in the NYC borough of Queens. In our Home Brew chat, we learn about the process of bringing this unique project to fruition directly from the composer and creators, including one of the oral history contributors: drummer, percussionist, composer, author, and educator Rafael Leal.https://cassyni-user-files-prod.s3.amazonaws.com/JwXFR1U7QWJNx8gghKse22 https://cassyni.com/events/6zND4Xc2xaUN1MPoy5i11P/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7T5ryFhScPtR664PCEq87Q https://cassyni.com/events/6zND4Xc2xaUN1MPoy5i11P?videoPreview=1 The Secret Link Between Global Media and World Politicsnohttps://cassyni.com/events/6zND4Xc2xaUN1MPoy5i11P?videoPreview=12024-09-12T12:00:00+00:004138.88Hong Kong Baptist UniversityThis is a talk by Professor Daya Thussu, Professor of International Communication Hong Kong Baptist University, on the rapidly evolving dynamics between global communication and geopolitics. He has recently published a book with the same title. The event was moderated by Mr. Gautam Chikermane, Vice President, Observer Research Foundation.https://cassyni-user-files-prod.s3.amazonaws.com/7T5ryFhScPtR664PCEq87Q https://cassyni.com/slides/outline/151JDma2jVj68xtL6zDeAq https://cassyni.com/events/151JDma2jVj68xtL6zDeAq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3tH9g82Sfu2CkWwefT4oEW https://cassyni.com/events/151JDma2jVj68xtL6zDeAq?videoPreview=1 Translating for Museums, Galleries and Heritage Sitesnohttps://cassyni.com/events/151JDma2jVj68xtL6zDeAq?videoPreview=12024-06-26T12:00:00+00:004071.28Hong Kong Baptist UniversityThe field of museum, gallery, and heritage site translation is gaining increasing recognition within both museum studies and translation studies, yet there remains a significant gap in research-informed practical training. This book, "Translating for Museums, Galleries, and Heritage Sites," addresses this need by providing a comprehensive, practice-oriented resource. It systematically examines "translations in the museum," encompassing interlingual, intersemiotic, and intralingual translation of interpretive and informational texts. The work is structured around a "museum text system" or "ecology of texts," analysing various textual layers, from fixed exhibition labels and wall panels to optional materials like leaflets and audio guides, and texts beyond the museum, such as catalogues and webpages. The book employs a non-language-specific approach, featuring authentic multilingual examples and pedagogical activities, including writing, translation, editing, and role-play exercises, to encourage reflection on contextual, linguistic, and intersemiotic challenges. Discussions among panellists reinforced the book's timely contribution. The "Translating Scotland's Heritage" network revealed a need for greater awareness of translation technologies like CAT tools, highlighted professional concerns about translation quality, and demonstrated the value of collaborative development, such as a translation brief template. Other perspectives underscored the imperative to maintain focus on interlingual translation within broader discussions of museums as cultural representations and the critical need for specialized training for museum translators. The book is anticipated to serve as a vital guide for practitioners and a catalyst for further research and training initiatives, bridging the divide between theoretical insights and practical application in museum translation.https://cassyni-user-files-prod.s3.amazonaws.com/3tH9g82Sfu2CkWwefT4oEW https://cassyni.com/slides/outline/3YFKTBoevnVaVuMteg8Gtm https://cassyni.com/events/3YFKTBoevnVaVuMteg8Gtm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5MDZ4q8v8kq6PgBhvbSnYW https://cassyni.com/events/3YFKTBoevnVaVuMteg8Gtm?videoPreview=1 Live Talk: Answering Covid-19 Questions to Help You Keep Calmnohttps://cassyni.com/events/3YFKTBoevnVaVuMteg8Gtm?videoPreview=12020-09-01T12:00:00+00:004548.44Hong Kong Baptist UniversityQUESTIONS: 1. Did God create malevolent viruses? 2. Should we consider COVID-19 as God's judgment of international sin in the world? 3. What does the Bible say about suffering from natural causes? 4. Are Christians immune to the virus, provided they have "strong faith"? 5. What does God expect of Christians in the midst of such a crisis as the present one? 6. Should Christians regard laws forbidding public worship at churches (though not shutting down supermarkets) as a problem of "obeying God or man"? How do Catholics and Protestants respond to this? 7. In a preface to a book, Pope Francis wrote: "“The presence of the Risen Lord in His Word and through the celebration of the Eucharist will give us the strength we need to resolve the difficulties and challenges that we will face after the coronavirus crisis.” Yes, but if Christ is risen, why do Christians need to go through suffering? Is Christian hope only about the hereafter or the coming world? How do we experience Christ's resurrection power in this life? 8. N.T. Wright has written a book "God and the Pandemic: A Christian Reflection on the Coronavirus and its Aftermath". He explains that when natural disaster hit the early church, they didn't ask theological questions but focused on collecting and sending help to the ones in need. How would you comment on that? 9. There are many ways in which Churches have gone online (Zoom, Google Meet, Livecast, FB streaming, etc). How do explain its theological significance in light of the New Testament? 10. How can a pastor fulfill his pastoring ministry during a lockdown situation?https://cassyni-user-files-prod.s3.amazonaws.com/5MDZ4q8v8kq6PgBhvbSnYW https://cassyni.com/slides/outline/FtTRcGymuELSPabhd2h12u https://cassyni.com/events/FtTRcGymuELSPabhd2h12u/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DEUJsGA4QB9CoqxX4oV4AA https://cassyni.com/events/FtTRcGymuELSPabhd2h12u?videoPreview=1 Developing Your Data Scraper: Data Harvest from Social Media Platformsnohttps://cassyni.com/events/FtTRcGymuELSPabhd2h12u?videoPreview=12023-06-21T12:00:00+00:006485.12Hong Kong Baptist UniversityThe seminar addresses the critical role of data harvesting from social media platforms in computational social science, emphasizing the growing importance of social media as a rich data source alongside traditional methods like surveys and experiments. It delineates two primary data collection approaches: Application Programming Interfaces (APIs) and web scraping. While APIs provide structured access to social media data, their availability and accessibility vary significantly across platforms, often restricted by authorization, rate limits, or prohibitive costs, as exemplified by Sina Weibo and Douyin. Consequently, web scraping emerges as a necessary alternative for platforms lacking open APIs, despite legal and ethical challenges such as terms of service violations, intellectual property concerns, privacy issues, and server overload risks. The seminar presents practical methodologies for developing custom data scrapers, including constructing large-scale user pools through follower network expansion and keyword-based filtering to build comprehensive datasets. Technical foundations are covered in detail, including HTTP protocols, HTML structure, XPath query language, and Python programming with libraries like requests and lxml for automated data extraction. Demonstrations include scraping posts from Weibo, retrieving restaurant data from OpenRice, and collecting Twitter data via APIs, with guidance on handling cookies, user agents, and data storage formats. The discussion highlights the importance of ethical considerations and technical adaptability in social media data collection, offering a framework for researchers to efficiently gather and manage large-scale social media datasets for quantitative analysis and network studies.https://cassyni-user-files-prod.s3.amazonaws.com/DEUJsGA4QB9CoqxX4oV4AA https://cassyni.com/slides/outline/ATKn6ks15CFMziMU27hD3T https://cassyni.com/events/ATKn6ks15CFMziMU27hD3T/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JC8W8YGXhuaNwznZ9v17E6 https://cassyni.com/events/ATKn6ks15CFMziMU27hD3T?videoPreview=1 Raven’s Hollow Composer: Robert Ellis-Geigernohttps://cassyni.com/events/ATKn6ks15CFMziMU27hD3T?videoPreview=12022-10-04T12:00:00+00:001619.44Hong Kong Baptist UniversityWest Point cadet Edgar Allan Poe and four other cadets on a training exercise in upstate New York are drawn by a gruesome discovery into a forgotten community. Listen to Robert talk about composing this film here!https://cassyni-user-files-prod.s3.amazonaws.com/JC8W8YGXhuaNwznZ9v17E6 https://cassyni.com/slides/outline/HrdW5ZqacefJHpr4jdryky https://cassyni.com/events/HrdW5ZqacefJHpr4jdryky/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FJk8zSngDCPcxwu5fj6N3G https://cassyni.com/events/HrdW5ZqacefJHpr4jdryky?videoPreview=1 Measure Intensity Using Praat - Ep.06nohttps://cassyni.com/events/HrdW5ZqacefJHpr4jdryky?videoPreview=12021-06-09T12:00:00+00:00170.92Hong Kong Baptist UniversityIntensity, a crucial acoustic property in speech analysis, is defined as the energy transmitted by a sound wave per second over one square meter and is generally correlated with perceived loudness. The Praat software provides a straightforward methodology for measuring the intensity of speech sounds. The process involves selecting a specific segment of an audio waveform, such as an entire word or a phonological unit like a vowel. To obtain an intensity measurement, the "Show intensity" option must be activated within Praat's Intensity menu, which generates a visual intensity curve. Subsequently, selecting "Get Intensity" yields a numerical value in decibels (dB) for the chosen segment. A common procedural error, omitting to activate "Show intensity," is addressed; Praat provides an error message instructing the user to enable this display option, thereby guiding them to successfully acquire the intensity measurement. This approach facilitates precise quantification of speech sound intensity for phonological and acoustic research.https://cassyni-user-files-prod.s3.amazonaws.com/FJk8zSngDCPcxwu5fj6N3G https://cassyni.com/slides/outline/LKsXJz5CowRnemKdHKmcUu https://cassyni.com/events/LKsXJz5CowRnemKdHKmcUu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8ZGFBVkWa4sR3zoyzXUHjc https://cassyni.com/events/LKsXJz5CowRnemKdHKmcUu?videoPreview=1 Natural Theology: A Reassessmentnohttps://cassyni.com/events/LKsXJz5CowRnemKdHKmcUu?videoPreview=12025-10-07T12:00:00+00:003465.76Hong Kong Baptist UniversityThis reassessment of natural theology argues for a traditional understanding, affirming what can be rationally believed about God without using religious doctrines as premises. It addresses the common misconception that David Hume and Immanuel Kant successfully rebutted arguments for God's existence, demonstrating their continued defence in contemporary academic philosophy. The study develops a rigorous, deductively valid formulation of the Cosmological Argument, complemented by considerations of teleological and moral arguments. A key component involves defending the causal principle, "whatever begins to exist has a cause," through a *modus tollens* argument grounded in immediate experience rather than inductive generalization. This approach establishes the necessity of a beginningless, changeless First Cause with libertarian freedom, identifiable as a personal agent distinct from an impersonal material universe. Integrating teleological considerations, this First Cause is further characterized as a highly intelligent and powerful creator God. The analysis addresses long-standing objections, including the "who made God?" question and the "God-of-the-gaps" fallacy, asserting that these conclusions are robust, logically sound, and cannot be overturned by future scientific discoveries.https://cassyni-user-files-prod.s3.amazonaws.com/8ZGFBVkWa4sR3zoyzXUHjc https://cassyni.com/slides/outline/Uito6c58Giqmp6g6MB6fho https://cassyni.com/events/Uito6c58Giqmp6g6MB6fho/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TUwKVW3uhXcQerXMGAWzcv https://cassyni.com/events/Uito6c58Giqmp6g6MB6fho?videoPreview=1 Recital-Palestra: Composer–Performer Collaborationnohttps://cassyni.com/events/Uito6c58Giqmp6g6MB6fho?videoPreview=12021-10-05T12:00:00+00:002109.44Hong Kong Baptist UniversityThis presentation examines the collaborative process between composer Camilo Mendez and soprano Dory Haley through three vocal works drawn from distinct compositional cycles: *Plegaria Muda*, *Archipelago Sierpinski* (specifically *Uslar/Gorong*), and *Bursztyn* (notably *Minimaquina IIIb*). The collaboration foregrounds an iterative, exploratory approach involving extensive sessions to develop extended vocal techniques, modular structures, and innovative instrumental modifications. *Plegaria Muda*—inspired by Colombian artist Doris Salcedo’s installation and Chilean writer Roberto Bolaño’s text—features a flexible five-section form allowing variable performance order, reflecting the installation’s mutable spatial configurations. This piece marked Mendez’s initial engagement with the voice as an instrument, prompting a compositional and performative expansion of Haley’s vocal palette through rapid shifts among extended techniques. *Uslar/Gorong*, composed for Haley and pianist Manuel Laufer, employs modular structures inspired by the fractal Sierpinski triangle and integrates performer actions inside the piano, necessitating novel notation systems and coordination adjustments due to handedness differences. The work explores a unified sound world where voice and piano sounds interweave, with the piano as the sonic center. The *Bursztyn* cycle, paying homage to sculptor Feliza Bursztyn, features altered instruments and a prepared megaphone through which Haley sings, transforming the vocal timbre and extending the concept of “impossible objects.” These collaborations demonstrate a symbiotic relationship that reshapes compositional practice and performer identity, highlighting the potential for composer–performer partnerships to expand technical and expressive boundaries in contemporary vocal music.https://cassyni-user-files-prod.s3.amazonaws.com/TUwKVW3uhXcQerXMGAWzcv https://cassyni.com/slides/outline/XC8pL2JkU1cGB39ets1JRj https://cassyni.com/events/XC8pL2JkU1cGB39ets1JRj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PP75oVerjNwiiUBBk84ZHx https://cassyni.com/events/XC8pL2JkU1cGB39ets1JRj?videoPreview=1 50 Years of Art Basel: the 2010snohttps://cassyni.com/events/XC8pL2JkU1cGB39ets1JRj?videoPreview=12020-12-17T12:00:00+00:003679.52Hong Kong Baptist UniversityThe final talk in our five-part series of Conversations marking 50 years of Art Basel explored how the Asia Pacific art scene – diverse in its cultures and histories – has risen to international prominence over recent decades. Central to the discussion was the launch of Art Basel Hong Kong in 2013, and its impact on the arts in the city and across the region.https://cassyni-user-files-prod.s3.amazonaws.com/PP75oVerjNwiiUBBk84ZHx https://cassyni.com/slides/outline/Tjbb1En5Pojd9Lr6FCdLtu https://cassyni.com/events/Tjbb1En5Pojd9Lr6FCdLtu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/S3vtiswCKWiDZd84HjXgxW https://cassyni.com/events/Tjbb1En5Pojd9Lr6FCdLtu?videoPreview=1 A Thomistic Critique of Panentheismnohttps://cassyni.com/events/Tjbb1En5Pojd9Lr6FCdLtu?videoPreview=12023-12-05T12:00:00+00:004156.76Hong Kong Baptist UniversityFr. James Dominic Rooney returns to Philosophy for the People to discuss his recent critique of panentheism.https://cassyni-user-files-prod.s3.amazonaws.com/S3vtiswCKWiDZd84HjXgxW https://cassyni.com/slides/outline/6Vic1qxWX7vK1arvNeRCk5 https://cassyni.com/events/6Vic1qxWX7vK1arvNeRCk5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FCCSF8DHxmdakSwXREvdE6 https://cassyni.com/events/6Vic1qxWX7vK1arvNeRCk5?videoPreview=1 Prairie Lights Readingnohttps://cassyni.com/events/6Vic1qxWX7vK1arvNeRCk5?videoPreview=12022-06-24T12:00:00+00:003470.6Hong Kong Baptist UniversityThis abstract summarizes a seminar featuring poetry readings by Arda Collins from her collection *Star Lake*, and by James Shea and Dorothy Tse presenting their co-translation, *Moving a Stone, Selected Poems of Yam Gong*. The seminar primarily focused on the distinctive poetry of Yam Gong, a self-taught Hong Kong poet (b. 1949), whose selected works span over four decades. His unique poetic approach incorporates Cantonese, including local slang, and integrates diverse linguistic influences such as biblical texts, classical Chinese, and English song lyrics. The selection of Yam Gong's poems explored a spectrum of human experience. "Daily Life" delves into childhood illness and the Cantonese folk ritual *hamgang* for soul retrieval. "And so you look at festival lights along the street" examines urban alienation, transient joy, and societal perceptions of happiness, contrasting public festivity with personal introspection. Philosophical inquiries into existence, separation, and the interplay of the finite and infinite appear in "Impromptu." "Salt of the Salterfish Shell" offers a poignant portrayal of Hong Kong's working-class life, highlighting dashed hopes and the struggle for recognition. Further explorations in "Deep river" address themes of life, death, silence, and the human voice, while "Meditation" draws on a French opera to discuss love, peace, and the search for meaning. The reading concluded with "Performance art for May," which considers artistic transformation, the enduring nature of art, and the complexities of understanding and forgetfulness. Yam Gong's poetry thus offers a rich commentary on Hong Kong culture, personal introspection, and universal human conditions through its unique linguistic and thematic tapestry.https://cassyni-user-files-prod.s3.amazonaws.com/FCCSF8DHxmdakSwXREvdE6 https://cassyni.com/slides/outline/ZEZZ1VG8YPHcV9aNAiD1w https://cassyni.com/events/ZEZZ1VG8YPHcV9aNAiD1w/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TV8gHuf7X46VgjAtSrevBp https://cassyni.com/events/ZEZZ1VG8YPHcV9aNAiD1w?videoPreview=1 Chinese SF in the Anthropocenenohttps://cassyni.com/events/ZEZZ1VG8YPHcV9aNAiD1w?videoPreview=12022-04-30T12:00:00+00:001385.8Hong Kong Baptist UniversityThis paper discusses the work of three Chinese science fiction writers from the perspective of a deepening ecological crisis that urges us to understand the close connections between society and ecology, to rethink anthropogenic practices, and to imagine an alternative future. Special attention will be paid to whether and how this ecological crisis is understood as multifaceted along the lines of social interaction, political economy, capitalist mechanisms and the interstate system. In Liu Cixin’s (劉慈欣) trilogy Remembrance of the Earth’s Past (地球往事三部曲), also known as the Three-Body series (三體系列) (2008–2011), one of the origins of the never-ending inter-galactic wars can be traced back to a Chinese scientist who, sharing the environmental concerns raised in Rachel Carson’s 1962 book Silent Spring, decides to seek help from an extraterrestrial civilisation out of despair at the ecological and human depravation witnessed during the Cultural Revolution. But the universe turns out to be a ‘dark forest’ where preventive warfare rages, reminiscent of a Hobbesian conception of international relations that pits great powers against each other in their quest for lebensraum and natural resources. In Hao Jingfang’s (郝景芳) 2014 novelette Folding Beijing (北京摺叠), the city folds itself into three different spaces at regular intervals to provide (unequal) access to sun, air and other resources for the ruling elite, the professionals, and the workers who are predominantly engaged in the waste processing industry. As the working-class protagonist trespasses the tightly policed boundaries between the different spaces, we get a glimpse of the changing cityscape as a nexus between ecology and capital, between government and international politics. In Chen Qiufan’s (陳楸帆, also known as Stanley Chan) 2013 novel The Waste Tide (荒潮), the female protagonist is a young migrant worker toiling in one of the many e-waste processing plants in Silicon Island, a fictional version of the world’s largest e-waste dumping ground at Guiyu in the province of Guangdong. A neurological virus transmitted through e-waste turns her into a cyborg that leads a rebellion against the exploitative plant owners. Juxtaposing these works of Chinese SF against the Chinese government’s conception of ecological civilisation, this paper aims to explore forms of agency that address the multifaceted nature of our ecological crisis.https://cassyni-user-files-prod.s3.amazonaws.com/TV8gHuf7X46VgjAtSrevBp https://cassyni.com/events/43d7UErDqd8cgecaEwsLiy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AJVJuVkNEJ88VvuPseCu3L https://cassyni.com/slides/outline/KrTKJ16g6MdfTWvn1KNWmB https://cassyni.com/events/KrTKJ16g6MdfTWvn1KNWmB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/MRL1UYSejLuTNA1gL55fDG https://cassyni.com/events/KrTKJ16g6MdfTWvn1KNWmB?videoPreview=1 12 Labours Seminar Series (Technology Platform 2): Clinical Workflowsnohttps://cassyni.com/events/KrTKJ16g6MdfTWvn1KNWmB?videoPreview=12021-11-30T23:00:00+00:003017.04Auckland Bioengineering InstituteThis seminar will present Technology Platform 2 of the 12 labours project: A Physiome modelling platform for precision medicine. We will describe our efforts to integrate existing workflow and FAIR data management systems to enable researchers to create personalised and automated clinical workflows using the computational physiology models they are developing. Our research into technologies to facilitate clinical translation of these workflows will also be described, including the acceleration of simulations and efforts towards accounting for modelling approximations and uncertainty quantification. We will also describe plans for deploying infrastructure to run these workflows as part of pilot studies within clinical environments.https://cassyni-user-files-prod.s3.amazonaws.com/MRL1UYSejLuTNA1gL55fDG https://cassyni.com/slides/outline/aVahLg9Fn4zEhkEtGS5UR https://cassyni.com/events/aVahLg9Fn4zEhkEtGS5UR/abstract https://cassyni-user-files-prod.s3.amazonaws.com/17s9kFcHRCmesTGCSmoAsx https://cassyni.com/events/aVahLg9Fn4zEhkEtGS5UR?videoPreview=1 Bringing metamaterials to creative industries and hospitalsnohttps://cassyni.com/events/aVahLg9Fn4zEhkEtGS5UR?videoPreview=12021-11-09T14:00:00+00:003968.08MetaMATAccording to different recent market research reports, acoustic metamaterials are quickly going up the TRL scale, moving to applications. In this talk, I will therefore present two examples of applications: one relative to sound delivery and one to noise management, both for audible frequencies in air. First, I will describe how combinations of metasurfaces can be used to achieve sound delivery with wavelength precision at variable distances, for creative applications. I will touch on the possibility of applying the thin-lens equation and on the verification of COMSOL simulations using human volunteers. Secondly, I will discuss how my team came to design meta-material based movable panels to COVID wards. I will touch on the criticality of noise in hospitals, on the specific combination of unit cells that we used and on the challenges to test the performance of our panels using standard techniques, both in the laboratory and in-situ. https://cassyni-user-files-prod.s3.amazonaws.com/17s9kFcHRCmesTGCSmoAsx https://cassyni.com/slides/outline/43mE3PRerRmFRLgRddAt7F https://cassyni.com/events/43mE3PRerRmFRLgRddAt7F/abstract https://cassyni-user-files-prod.s3.amazonaws.com/ALtxz8KFrPDVCxqfvUcu3L https://cassyni.com/events/43mE3PRerRmFRLgRddAt7F?videoPreview=1 The 2nd World Logic Prizes Contestnohttps://cassyni.com/events/43mE3PRerRmFRLgRddAt7F?videoPreview=12022-03-09T11:40:00+00:003297.72Logica UniversalisI discuss the origin and development of logic prizes around theworld. In a first section I describe how I started this project by creatingthe Newton da Costa Logic Prize in Brazil in 2014. In a second section Iexplain how this idea was extended into the world through the manifestoA Logic Prize in Every Country! and how was organized the Logic PrizesContest at the 6th UNILOG (World Congress and School on UniversalLogic) in Vichy in June 2018 with the participation of 9 logic prizes win-ners from 9 countries. In a third section I discuss how this project willdevelop in the future with the creation of more logic prizes, an Ency-clopædia of Logic, the book series Logic PhDs, as well as the creation of aWorld Logic Day, January 14, day of birth of Alfred Tarski and of deathof Kurt G¨odel.https://cassyni-user-files-prod.s3.amazonaws.com/ALtxz8KFrPDVCxqfvUcu3L https://cassyni.com/slides/outline/KMkU24RNrBE4p3to3hp3Su https://cassyni.com/events/KMkU24RNrBE4p3to3hp3Su/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JGirr4ASK6LJnoTK915JAJ https://cassyni.com/events/KMkU24RNrBE4p3to3hp3Su?videoPreview=1 Hdecay: Precise Higgs-boson Decay Ratesnohttps://cassyni.com/events/KMkU24RNrBE4p3to3hp3Su?videoPreview=12021-08-24T15:00:00+00:002956.96Computer Physics CommunicationsThe program HDECAY determines the partial decay widths and branching ratios of the Higgs bosons within the Standard Model with three and four generations of fermions, including the case when the Higgs couplings are rescaled, a general two--Higgs doublet model where the Higgs sector is extended and incorporates five physical states and its most studied incarnation, the minimal supersymmetric Standard Model (MSSM). The program addresses all decay channels including the dominant higher-order effects such as radiative corrections and multi-body channels. Since the first launch of the program, more than twenty years ago, important aspects and new ingredients have been incorporated. In this update of the program description, some of the developments are summarized while others are discussed in some detail.https://cassyni-user-files-prod.s3.amazonaws.com/JGirr4ASK6LJnoTK915JAJ https://cassyni.com/slides/outline/SGpvfdUizayrJrtNR9Nybb https://cassyni.com/events/SGpvfdUizayrJrtNR9Nybb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LW9LvNLVMQxdwzNFxeesAN https://cassyni.com/events/SGpvfdUizayrJrtNR9Nybb?videoPreview=1 Synthesis and Reactivity of a Ytterbium(II) Hydridenohttps://cassyni.com/events/SGpvfdUizayrJrtNR9Nybb?videoPreview=12021-08-05T00:15:00+00:002948.96The MacDiarmid Institute for Advanced Materials and NanotechnologyWe have recently reported that a ytterbium(II) hydride reacts with ethene and propene to provide the respective ytterbium(II) n-alkyls, both of which alkylate benzene at room temperature. Density functional theory (DFT) calculations indicate that this latter process operates through the nucleophilic (SN2) displacement of hydride, while the resultant regeneration of ytterbium(II) hydride facilitates further reaction with ethene or propene and enables the direct catalytic (anti-Markovnikov) hydroarylation of both alkenes with a benzene C-H bond. This seminar will cover this reactivity and the extension of our studies to the reduction of polyaromatic hydrocarbons.https://cassyni-user-files-prod.s3.amazonaws.com/LW9LvNLVMQxdwzNFxeesAN https://cassyni.com/slides/outline/LM8YTKG5wB7VGyvHoRVUwP https://cassyni.com/events/LM8YTKG5wB7VGyvHoRVUwP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JNVC4yX3kA7Znhturn7vi2 https://cassyni.com/events/LM8YTKG5wB7VGyvHoRVUwP?videoPreview=1 Space-time metamaterials: dragging and amplifying lightnohttps://cassyni.com/events/LM8YTKG5wB7VGyvHoRVUwP?videoPreview=12021-04-20T14:00:00+00:004777.56MetaMATIn this talk I will consider space-time metamaterials of travelling-wave type [1] and present a theory of homogenisation of these modulated media [2]. This framework provides analytical expressions for the effective permittivity, permeability and magnetoelectric coupling of these media in the long wavelength limit. From the derived parameters we will see how it is possible to achieve nonreciprocal effects away from the asymmetric band gaps, and even down to the quasistatic limit if both the permittivity and permeability are modulated. This way, the synthetic motion present in these systems allows a new and tunable form of Fresnel drag effect of light in moving media [3]. The theory unveils a regime where the modulation speed approaches that of waves in the background medium where homogenisation breaks down and a new mechanism for gain emerges [4], enabling a form of nonreciprocal broadband amplification that could be realised in graphene [5]. On the other hand, temporal only modulations enable novel ways to excite surface waves from the far field [6].https://cassyni-user-files-prod.s3.amazonaws.com/JNVC4yX3kA7Znhturn7vi2 https://cassyni.com/slides/outline/Uk9pEwG1PxXUSKGksGpYAH https://cassyni.com/events/Uk9pEwG1PxXUSKGksGpYAH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LbQQn3vuiic1K9iv9hSJAA https://cassyni.com/events/Uk9pEwG1PxXUSKGksGpYAH?videoPreview=1 Wave Interaction with Subwavelength Resonatorsnohttps://cassyni.com/events/Uk9pEwG1PxXUSKGksGpYAH?videoPreview=12020-11-17T14:00:00+00:005266.16MetaMATIn this lecture, the speaker reviews recent results on subwavelength resonances. His main focus is on developing a mathematical and computational framework for their analysis. By characterizing and exploiting subwavelength resonances in a variety of situations, he proposes a mathematical explanation for super-focusing of waves, double-negative metamaterials, Dirac singularities in honeycomb subwavelength structures, and topologically protected defect modes at the subwavelength scale. He also describes a new resonance approach for modelling the cochlea which predicts the existence of a travelling wave in the acoustic pressure in the cochlea fluid and offers a basis for the tonotopic map.https://cassyni-user-files-prod.s3.amazonaws.com/LbQQn3vuiic1K9iv9hSJAA https://cassyni.com/slides/outline/XDPqUMVdbFHxoFkKQxjAtD https://cassyni.com/events/XDPqUMVdbFHxoFkKQxjAtD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QYbF9X77EP2nh45pDztWWr https://cassyni.com/events/XDPqUMVdbFHxoFkKQxjAtD?videoPreview=1 Odd robotic matternohttps://cassyni.com/events/XDPqUMVdbFHxoFkKQxjAtD?videoPreview=12021-10-05T14:00:00+00:004390.68MetaMATControlling how waves propagate, attenuate and amplify in simple, scalable geometric structures is a daunting challenge for science and technology. In this talk, I will discuss how odd media—media in which energy conservation and chiral symmetries are simultaneously broken—can be used to steer mechanical waves in unprecedented ways. Combining experiments on mechanical lattices of distributed robots with wave physics and continuum mechanics, I will discuss the emergence of unidirectionally amplified waves, of topological waves and of one-way solitons in odd media. I will further show how these odd waves can be used to induce locomotion and unusual responses to impacts and hence pave the way towards a novel generation of materials with animate properties.https://cassyni-user-files-prod.s3.amazonaws.com/QYbF9X77EP2nh45pDztWWr https://cassyni.com/slides/outline/RHaxoXDSvPj4avWa1wcQiZ https://cassyni.com/events/RHaxoXDSvPj4avWa1wcQiZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BwpTMDdw517PjGNMq5kGJr https://cassyni.com/events/RHaxoXDSvPj4avWa1wcQiZ?videoPreview=1 The fish, it’s gone! The koi, I mean. Dislocations, movements, and afterthoughts: how are they expressed in Afrikaans? How do they differ from Dutch?nohttps://cassyni.com/events/RHaxoXDSvPj4avWa1wcQiZ?videoPreview=12021-10-01T03:00:00+00:002202.64Linguistics and Applied Language StudiesIn this presentation, the left and right peripheries of Afrikaans, a West Germanic language indigenous to South Africa, will be examined. The focus of the presentation will be on the various types of constructions associated with the respective peripheries, as well as their underlying information structure and their specific roles in discourse. Afrikaans is a relatively young language, having developed from 17th century Dutch after Dutch settlers formed a colony and trading station at Cape Town in 1652 (Van Huyssteen et al., 2015; van Rensburg, 2019). Therefore, comparisons will be drawn to similar constructions in Dutch to demonstrate how the language has changed over the years yet continues to utilise equivalent constructions despite no longer having access to all the morphological processes of Dutch. Building on the basic assumptions of the Minimalist Programme, this paper draws heavily from Rizzi’s cartographic approach to the left periphery (1997). The Afrikaans-Dutch discussion will be built on de Vries’s series of work on Dutch’s A-bar syntax as well as recent studies on the information structure of the left and right peripheries of Germanic languages (de Vries, 2007, 2009; Kalbertodt et al, 2015; Ott & de Vries, 2016). https://cassyni-user-files-prod.s3.amazonaws.com/BwpTMDdw517PjGNMq5kGJr https://cassyni.com/slides/outline/3Z4NmSkMcFMenBEHdrDk29 https://cassyni.com/events/3Z4NmSkMcFMenBEHdrDk29/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5XPbkLE7N3uhuSftyBMrhk https://cassyni.com/events/3Z4NmSkMcFMenBEHdrDk29?videoPreview=1 What matters in vocabulary learning?nohttps://cassyni.com/events/3Z4NmSkMcFMenBEHdrDk29?videoPreview=12020-05-01T16:00:00+00:005998.96Linguistics and Applied Language StudiesThe two basic conditions needed for effective vocabulary learning are repetition and quality of processing. Repetition is so important that it needs to be planned into a language course in a principled way. This talk will describe various ways to do this. Around one-third of the course time should be spent coming back to previously met material and language items. Quality of processing refers to the conditions involved in each meeting with a word. These conditions include noticing, spacing, retrieval, varied meetings and varied use, elaboration and deliberate attention. This talk shows how these conditions can be part of typical teaching and learning activities, and how teachers can make sure they occur.https://cassyni-user-files-prod.s3.amazonaws.com/5XPbkLE7N3uhuSftyBMrhk https://cassyni.com/slides/outline/AU8qR1ohkf7SGzDs1HngAq https://cassyni.com/events/AU8qR1ohkf7SGzDs1HngAq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7unD8ekkTFNzs34zSv3QsG https://cassyni.com/events/AU8qR1ohkf7SGzDs1HngAq?videoPreview=1 The Inviscid Primitive Equations and the Effect of Rotationnohttps://cassyni.com/events/AU8qR1ohkf7SGzDs1HngAq?videoPreview=12020-11-16T15:00:00+00:003227.12Partial Differential Equations and ApplicationsLarge scale dynamics of the oceans and the atmosphere is governed by the primitive equations (PEs). It is well-known that the three-dimensional viscous primitive equations are globally well-posed in Sobolev spaces. In this talk, I will discuss the ill-posedness in Sobolev spaces, the local well-posedness in the space of analytic functions, and the finite-time blowup of solutions to the three-dimensional inviscid PEs with rotation (Coriolis force). Eventually, I will also show, in the case of "well-prepared" analytic initial data, the regularizing effect of the Coriolis force by providing a lower bound for the life-span of the solutions which grows toward infinity with the rotation rate. The latter is achieved by a delicate analysis of a simple limit resonant system whose solution approximate the corresponding solution of the 3D inviscid PEs with the same initial data.https://cassyni-user-files-prod.s3.amazonaws.com/7unD8ekkTFNzs34zSv3QsG https://cassyni.com/events/HstXDu2TjtLzv3SjFjarDT/seminar/qa https://cassyni.com/slides/outline/HstXDu2TjtLzv3SjFjarDT https://cassyni.com/events/HstXDu2TjtLzv3SjFjarDT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DKvy8J2SVYcfBNpmAY17Mp https://cassyni.com/events/HstXDu2TjtLzv3SjFjarDT?videoPreview=1 micrOMEGAS - a code for calculating dark matter propertiesnohttps://cassyni.com/events/HstXDu2TjtLzv3SjFjarDT?videoPreview=12022-01-11T16:00:00+00:003518.0Computer Physics CommunicationsmicrOMEGAs is a code for the calculation of Dark Matter Properties in generic models of New Physics. In particular it allows to compute the relic density of dark matter, the rates for direct and indirect detection of dark matter as well as the prediction for dark matter production at colliders. In this talk I will first present the evidence for dark matter and describe the motivation for having a code that automatically computes the signatures and constraints on a new weakly interacting dark matter particle. After describing the general structure of the code. I will discuss issues related to the computation of the dark matter relic density, a well measured observable, as well as the computation of the rate for dark matter scattering on nucleus relevant for direct detection. A few extensions of the basic features of the code will be mentioned. https://cassyni-user-files-prod.s3.amazonaws.com/DKvy8J2SVYcfBNpmAY17Mp https://cassyni.com/slides/outline/PohPtjJeQjuu8NgUekhcP7 https://cassyni.com/events/PohPtjJeQjuu8NgUekhcP7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/C7MjkeJWtiWtMsJH7MjiHk https://cassyni.com/events/PohPtjJeQjuu8NgUekhcP7?videoPreview=1 Learning Preferences for Interactive Autonomynohttps://cassyni.com/events/PohPtjJeQjuu8NgUekhcP7?videoPreview=12022-03-10T16:15:00+00:003246.48Department of AeronauticsIn human-robot interaction or more generally multi-agent systems, we often have decentralized agents that need to perform a task together. In such settings, it is crucial to have the ability to anticipate the actions of other agents. Without this ability, the agents are often doomed to perform very poorly. Humans are usually good at this, and it is mostly because we can have good estimates of what other agents are trying to do. We want to give such an ability to robots through reward learning and partner modeling. In this talk, I am going to talk about active learning approaches to this problem and how we can leverage preference data to learn objectives. I am going to show how preferences can help reward learning in the settings where demonstration data may fail, and how partner-modeling enables decentralized agents to cooperate efficiently.https://cassyni-user-files-prod.s3.amazonaws.com/C7MjkeJWtiWtMsJH7MjiHk https://cassyni.com/slides/outline/8zDePbP1qeNpjHGhr9HotR https://cassyni.com/events/8zDePbP1qeNpjHGhr9HotR/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6drD6sS3ML9yLtM82jumi6 https://cassyni.com/events/8zDePbP1qeNpjHGhr9HotR?videoPreview=1 Influence of speaker sex and f0 on creaky voice identification by Australian English-speaking femalesnohttps://cassyni.com/events/8zDePbP1qeNpjHGhr9HotR?videoPreview=12022-05-13T04:00:00+00:003038.24Linguistics and Applied Language StudiesCreaky voice is a nonmodal voice quality that is generally considered to be perceptually rough and low in pitch. In both linguistic research and media articles, creaky voice has been linked to the speech of females. Our past work raised questions about how creaky voice is perceived in different voices, particularly whether greater pitch differences between a speaker’s modal and creaky voices facilitates creak identification or whether listeners are biased to perceive creak in certain voices due to social expectations. While previous work has investigated the role that speaker sex and pitch play in creak identification, results have been inconclusive (Davidson, 2019). In this study, we use highly controlled stimuli to examine whether and in what way f0 and/or speaker sex are salient cues to creak identification. A perception study of 130 Australian English-speaking female listeners found that f0 and speaker sex both play a significant role for these listeners in identifying creaky voice.https://cassyni-user-files-prod.s3.amazonaws.com/6drD6sS3ML9yLtM82jumi6 https://cassyni.com/slides/outline/RnHp5TtkAa8fE5xi1iZYof https://cassyni.com/events/RnHp5TtkAa8fE5xi1iZYof/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5jVUEB1mAozowp4bvWFTyg https://cassyni.com/events/RnHp5TtkAa8fE5xi1iZYof?videoPreview=1 Biofilms and Surgical Infections - Strategies for Treatmentnohttps://cassyni.com/events/RnHp5TtkAa8fE5xi1iZYof?videoPreview=12022-09-13T04:00:00+00:003822.08The Auckland Bioengineering InstituteMost bacteria (~98%) in nature are found in biofilms. Biofilms confer protection and a medium for exchange of nutrients, and information to individual bacteria. This enables the bacteria to collectively survive harsh environments. It is therefore not surprising that biofilms are found in nearly all chronic infections. The additional protection enables biofilms to resist antibiotic treatments and achieving antibiotic concentrations capable of biofilm eradication in-vivo can be difficult or impossible. This talk will focus on surgical infections, sources of infection, treatment strategies and in-vitro, in-vivo and in-silico models used to investigate the efficacy of the antibiotics and treatment strategies. Specific focus will be on Lactoferrin- a naturally occurring glycoprotein with immune function, and its impact on the efficacy of the antibiotic treatment against biofilms.https://cassyni-user-files-prod.s3.amazonaws.com/5jVUEB1mAozowp4bvWFTyg https://cassyni.com/slides/outline/UFXqJt8NMru9b2SGZQUBXb https://cassyni.com/events/UFXqJt8NMru9b2SGZQUBXb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/F5EiAVwpydmUvY7cEGFnFY https://cassyni.com/events/UFXqJt8NMru9b2SGZQUBXb?videoPreview=1 Statistical mechanics of systems with negative temperaturenohttps://cassyni.com/events/UFXqJt8NMru9b2SGZQUBXb?videoPreview=12022-06-20T12:00:00+00:004100.16Physics ReportsAre negative absolute temperatures relevant physics and specifically Statistical Physics? We provide evidence that we can certainly answer positively to this vexata quaestio. The great majority of models investigated by statistical mechanics over almost one century and a half exhibit positive absolute temperature, because their entropy is a nondecreasing function of energy. Since more than half a century ago it has been realized that this may not be the case for some physical systems as incompressible fluids, nuclear magnetic chains, lasers, cold atoms and optical waveguides. We discuss these examples and their peculiar thermodynamic properties, which have been associated to the presence of thermodynamic regimes, characterized by negative absolute temperatures. The ambiguity regarding the definition of entropy has recurrently raised a harsh debate about the possibility of considering negative temperature states as genuine thermodynamic equilibrium ones. We show that negative absolute temperatures are consistent with equilibrium as well as with non-equilibrium thermodynamics. https://cassyni-user-files-prod.s3.amazonaws.com/F5EiAVwpydmUvY7cEGFnFY https://cassyni.com/events/534S8kihjLsQ66WRjbeCv9/seminar/qa https://cassyni.com/events/534S8kihjLsQ66WRjbeCv9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AXSmPP4cWfuFKfmUBoRaQe https://cassyni.com/slides/outline/7WJTNAxKvddtT2yzHHYqe5 https://cassyni.com/events/7WJTNAxKvddtT2yzHHYqe5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7FEAtTFt97v9fUPnuV7T3L https://cassyni.com/events/7WJTNAxKvddtT2yzHHYqe5?videoPreview=1 Vorticity dynamics in breaking wavesnohttps://cassyni.com/events/7WJTNAxKvddtT2yzHHYqe5?videoPreview=12022-04-12T10:40:00+00:001662.36Water WavesNumerical investigation of the breaking of a 3D steep periodic wave is conducted with a primary focus on the vorticity dynamics and energy dissipation mechanisms. Simulations are performed at the same Weber number and different Reynolds numbers. The analysis covers the bubble size distribution, its evolution in time, and viscous dissipation. Particular attention is paid to the analysis of the "vortex sheets", i.e. zones of locally nearly two-dimensional shearing motion, and their role on the development of vortex tubes. Whereas the total energy fraction dissipated by the breaking is about independent of the Reynolds number, the vorticity dynamics, the dissipation mechanisms, and the interaction between bubbles and vortex structures are shown to be remarkably different.https://cassyni-user-files-prod.s3.amazonaws.com/7FEAtTFt97v9fUPnuV7T3L https://cassyni.com/slides/outline/Ev2X4RfCWVwiwcWTFAQa45 https://cassyni.com/events/Ev2X4RfCWVwiwcWTFAQa45/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9MjsTubdzGjsvXx37wKVMx https://cassyni.com/events/Ev2X4RfCWVwiwcWTFAQa45?videoPreview=1 A Venn Diagram System for Universe Without Boundarynohttps://cassyni.com/events/Ev2X4RfCWVwiwcWTFAQa45?videoPreview=12021-07-21T10:40:00+00:005394.28Logica UniversalisA new diagram system Vennio1 where properties are fundamental and an object exists only w.r.t a property is presented. This work modifies both in syntax and semantics the system Vennio proposed by Choudhury and Chakraborty to picturise and address issues connected with open universe. Semantics for the current system is given. Soundness and completeness w.r.t the semantics are established.https://cassyni-user-files-prod.s3.amazonaws.com/9MjsTubdzGjsvXx37wKVMx https://cassyni.com/slides/outline/GteZMnmBfh6DBoV5thCx7F https://cassyni.com/events/GteZMnmBfh6DBoV5thCx7F/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9Eq1ZB7h3QypvNKLxrJJwg https://cassyni.com/events/GteZMnmBfh6DBoV5thCx7F?videoPreview=1 Marjorie, the Met, and Managing the Intelligencernohttps://cassyni.com/events/GteZMnmBfh6DBoV5thCx7F?videoPreview=12021-02-27T16:00:00+00:001080.04Mathematical IntelligencerNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/9Eq1ZB7h3QypvNKLxrJJwg https://cassyni.com/slides/outline/SGy3En4A1PcV3YxDopgWys https://cassyni.com/events/SGy3En4A1PcV3YxDopgWys/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XTj3AsHVE9aXcBowtDbnJ2 https://cassyni.com/events/SGy3En4A1PcV3YxDopgWys?videoPreview=1 Axiomatization of Some Basic and Modal Boolean Connexive Logicsnohttps://cassyni.com/events/SGy3En4A1PcV3YxDopgWys?videoPreview=12022-07-14T13:00:00+00:004272.16Logica UniversalisBoolean connexive logic is an extension of Boolean logic that is closed under Modus Ponens and contains Aristotle's and Boethius' theses. According to these theses (i) a sentence cannot imply its negation and the negation of a sentence cannot imply the sentence; and (ii) if the antecedent implies the consequent, then the antecedent cannot imply the negation of the consequent and if the antecedent implies the negation of the consequent, then the antecedent cannot imply the consequent. Such a logic was first introduced by Jarmużek and Malinowski, by means of so-called relating semantics and tableau systems. Subsequently its modal extension was determined by means of the combination of possible-worlds semantics and relating semantics. In the following article we present axiomatic systems of some basic and modal Boolean connexive logics. Proofs of completeness will be carried out using canonical models defined with respect to maximal consistent sets.https://cassyni-user-files-prod.s3.amazonaws.com/XTj3AsHVE9aXcBowtDbnJ2 https://cassyni.com/slides/outline/SmceHThgSrAY3KV7QFyKFB https://cassyni.com/events/SmceHThgSrAY3KV7QFyKFB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FXEtdVXeTLLaCYtu12BSJa https://cassyni.com/events/SmceHThgSrAY3KV7QFyKFB?videoPreview=1 CO2 capture and utilisation and the integration, Conversion of CO2 into chemicals and fuelsnohttps://cassyni.com/events/SmceHThgSrAY3KV7QFyKFB?videoPreview=12022-09-20T09:00:00+00:004426.84ElsevierCO2 capture and utilization (CCU) is a sustainable process that can partially close the carbon cycle. It is attractive to store the excess and uncertain supply of energy from renewable sources to stable chemical energy. Increasing studies have been carried out on integrated CO2 capture and utilization (ICCU) to reduce the cost of the overall process by eliminating transportation and storage of the CO2. ICCU could achieve in-situ CO2 adsorption, separation and conversion using dual-function catalysts (DFMs), consisting of CO2 adsorbents and catalysts. ICCU avoid temperature swing sorbent regeneration, which is considered an energy-intensive process. Integrating CO2 capture and utilization via reverse water-gas shift reaction (ICCU-RWGS) is particularly attractive due to the important industrial value of syngas. Furthermore, the in-situ CO2 utilization can outperform conventional RWGS in relation to CO2 conversion and CO selectivity. Herein, we achieved very promising ICCU-RWGS performance by CaO-alone and functionalizing CaO using active transition metals (e.g. Ni and Fe). Excellent CO2 adsorption and extremely efficient CO2 conversion can be achieved with simple materials, outperforming traditional separated CO2 capture and catalytic conversion processes. Currently, the conversion of captured CO2 into value-added chemicals or fuels is considered a key strategy to mitigate the yet increasing anthropogenic CO2 emissions, in particular when combined with H2 obtained using renewable energy. Depending on the catalyst and the reaction conditions used, thermocatalytic CO2 hydrogenation can give CO, methanol, dimethyl ether (DME), methane, or heavier hydrocarbons. MXene materials, that is, a family of two-dimensional (2D) carbides, nitrides and carbonitrides with the general formula of Mn +1XnTx (where M is an early transition metal, n = 1, 2, 3, X is C and/or N and T are surface –O–, –OH and/or –F groups), are currently emerging in thermocatalytic applications as catalysts or supports with reactive metal–support interactions. Enabled by the scalable synthesis of MXenes, we report a gram-scale synthesis of a phase-pure multilayered hexagonal 2D-Mo2C material with only Mo-terminated basal planes. 2D-Mo2C is by a factor of six per mass of catalyst more active for CO formation than the reference β-Mo2C catalyst and shows no deactivation on stream for more than 100 h. We also report that silica-supported, dispersed, reducible nanosheets of a delaminated molybdenum MXene, Mo2CTx, can be used to engineer a Cu/Mo2CTx interface that shows an at least six times increased intrinsic formation rate of methanol by the direct hydrogenation of CO2 compared to Cu/SiO2.https://cassyni-user-files-prod.s3.amazonaws.com/FXEtdVXeTLLaCYtu12BSJa https://cassyni.com/slides/outline/WDmA1S1wt156NTyevLPDGh https://cassyni.com/events/WDmA1S1wt156NTyevLPDGh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KrunBQqpHtPv3mS2Lkk4rJ https://cassyni.com/events/WDmA1S1wt156NTyevLPDGh?videoPreview=1 Rare-earth Nitrides: from film growth in molecular nitrogen to ammonia catalysis.nohttps://cassyni.com/events/WDmA1S1wt156NTyevLPDGh?videoPreview=12022-12-14T18:00:00+00:003723.68School of Chemical and Physical SciencesWhen the rare earth mononitrides (RENs) first burst onto the scientific scene in the middle of last century, there were feverish dreams that their strong magnetic moment would afford a wide range of applications. For decades research was frustrated by poor stoichiometry and the ready reaction of the materials in ambient conditions, and only recently have these impediments finally been overcome by advances in thin film fabrication with ultra-high vacuum based growth technology. Currently, the field of research into the RENs is growing rapidly, motivated by spintronic structures and devices to advance and support quantum and superconducting computing. The technology depends critically on the formation of REN thin films, for which the optimum growth is to form the nitrides within an atmosphere of pure molecular nitrogen. The process is surprisingly efficient, and such catalytic activity of a clean RE surface opened much more widely important implications. Recently, we have demonstrated that the novel and easy breaking of molecular nitrogen gas under mild conditions on a clean lanthanide surface can be used to ammonia (NH3) at ambient temperature and low pressure, opening the door to a promising new class of catalyst that is not bound by the scaling relations of industrial transition metal-based catalysts. https://cassyni-user-files-prod.s3.amazonaws.com/KrunBQqpHtPv3mS2Lkk4rJ https://cassyni.com/slides/outline/9Ub2HysgFVfewC1xYAUatd https://cassyni.com/events/9Ub2HysgFVfewC1xYAUatd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4jF4n7KN1jQvjupvpprizz https://cassyni.com/events/9Ub2HysgFVfewC1xYAUatd?videoPreview=1 Research Writing - Part 2nohttps://cassyni.com/events/9Ub2HysgFVfewC1xYAUatd?videoPreview=12023-09-19T18:30:00+00:003172.44SCIWRITERThis seminar will explain how authors can improve their academic writing using Writefull and Writefull's AI-backed language models. Writefull's automated proofreading and tailored writing widgets will be highlighted, demonstrating how Writefull and AI can help throughout the whole writing process. Writefull offers AI-based language feedback and big data insights to help authors and copy editors improve their texts. Brought to you by a team of researchers in linguistics and AI, Writefull uses the latest techniques to enhance technical and scientific writing. Writefull's feedback is tailored to academic writing, as our language models have been trained on millions of published academic articles. The rise of generative AI has made it easier than ever to write a paper. This will lead to ever increasing volumes of publication and heighten the threat of paper mills, which submit plausible sounding but false or useless manuscripts for publication, eroding our ability to trust what we find in the literature. While AI will be a part of the solution to this problem, we also believe that video will play an increasingly important role. I recently spoke about how the future of scholarly publishing is video [1]. In this talk I will outline how giving a seminar about your research allows you to stand out from the masses of written manuscripts and add nuance and detail to the story of your research. Overleaf is an online, collaborative LaTeX editor used to create scientific documents. Overleaf's real-time collaborative features have revolutionized the way researchers and professionals work on LaTeX documents, enabling seamless collaboration across geographical boundaries. Features such as real-time tracked changes, integrations with Zotero, Mendeley, and GitHub further enhance the productivity gained by using Overleaf. AI-based editing tools such as Writefull can also be used with Overleaf via a browser extension.https://cassyni-user-files-prod.s3.amazonaws.com/4jF4n7KN1jQvjupvpprizz https://cassyni.com/slides/outline/HtJrwLkknJEu7CtkYFfUgm https://cassyni.com/events/HtJrwLkknJEu7CtkYFfUgm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3ihuJdvYZDv7r6uUQHA6sG https://cassyni.com/events/HtJrwLkknJEu7CtkYFfUgm?videoPreview=1 Unravelling a diversity of cellular structures and aggregation dynamics during the early development of Myxococcus xanthusnohttps://cassyni.com/events/HtJrwLkknJEu7CtkYFfUgm?videoPreview=12024-11-10T12:00:00+00:00946.48Royal Society PublishingAggregation underlies collective dynamics of a diversity of organisms, enabling the formation of complex structures and emergent behaviours in interaction with the environment. Cellular aggregation constitutes one of the routes to collective motility and multicellular development. Myxococcus xanthus, a social bacterium, is a valuable model for studying the aggregative way to multicellularity, a major transition in the evolutionary history of life. While the collective developmental behaviour of M. xanthus has been largely studied in high cellular densities, there is a lack of understanding at low density conditions that can be ecologically relevant. In this work, we study the early stages of emergent collective behaviour of M. xanthus under nutrient-poor and low density conditions, uncovering the formation of diverse cellular structures with different shapes and sizes, ranging from individual cells to networks comprising thousands of cells. We study their motility patterns and their prevalence along development, and discuss their cross-scale role on the population’s exploratory dynamics. This work contributes to understanding key, yet largely understudied, aspects in the early stages of multicellular development in myxobacteria, shedding light on the dynamics underlying aggregative processes in this and other taxa and study systems.https://cassyni-user-files-prod.s3.amazonaws.com/3ihuJdvYZDv7r6uUQHA6sG https://cassyni.com/events/Uka9xNzJSNRNdUin9nuAdb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XQmiPfnbfdSUTc9127xhQr https://cassyni.com/slides/outline/KNJvJej6uPkbjuQfiuCDJV https://cassyni.com/events/KNJvJej6uPkbjuQfiuCDJV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/E3jTVpXG97tLBnUvGu6Ckn https://cassyni.com/events/KNJvJej6uPkbjuQfiuCDJV?videoPreview=1 Off-target effects of nervous system drugs on the human gut microbiomenohttps://cassyni.com/events/KNJvJej6uPkbjuQfiuCDJV?videoPreview=12025-01-21T15:00:00+00:00929.16Microbiome Virtual International ForumMany human-targeted drugs alter the gut microbiome, leading to implications for host health. However, the mechanisms underlying these effects are not well known. Here we combined quantitative microbiome profiling, long-read metagenomics, stable isotope probing and single-cell chemical imaging to investigate the impact of two widely prescribed drugs on the gut microbiome. Physiologically relevant concentrations of entacapone, a treatment for Parkinson’s disease, or loxapine succinate, used to treat schizophrenia, were incubated ex vivo with human faecal samples. Both drugs significantly impact microbial activity, more so than microbial abundance. Mechanistically, entacapone can complex and deplete available iron resulting in gut microbiome composition and function changes. Microbial growth can be rescued by replenishing levels of microbiota-accessible iron. Further, entacapone-induced iron starvation selected for iron-scavenging gut microbiome members encoding antimicrobial resistance and virulence genes. These findings reveal the impact of two under-investigated drugs on whole microbiomes and identify metal sequestration as a mechanism of drug-induced microbiome disturbance.https://cassyni-user-files-prod.s3.amazonaws.com/E3jTVpXG97tLBnUvGu6Ckn https://cassyni.com/slides/outline/9VKDGMGiiskYjuiEvmVQXw https://cassyni.com/events/9VKDGMGiiskYjuiEvmVQXw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LZCMU6MnUAqVWCNzPubZTk https://cassyni.com/events/9VKDGMGiiskYjuiEvmVQXw?videoPreview=1 Open Scholarship Beyond The Labnohttps://cassyni.com/events/9VKDGMGiiskYjuiEvmVQXw?videoPreview=12021-09-22T03:00:00+00:006887.24UKRNMike Kelly will start the session by introducing some key themes, in part inspired by his research into archaeology’s multidisciplinary approaches to interpreting historical cultures and its strategies for dealing with uncertainty. These include the potential of using digital tools for documenting process and making researcher assumptions explicit; and how interactive publishing models might foster inclusivity and transparency in research. Dr Melodee Beals will discuss the history of reproducibility in the humanities and how we might build upon these rich traditions in an age of computer-aided open research. In this part of the workshop, we explore publishing Open Research by designing a research project that makes the most of open access article types, but reflects the realities of how scholars in the arts & humanities conduct and share their research. The Open Research movement proposes that scholars should strive for openness throughout the research cycle by encouraging and acknowledging collaborative working, sharing methodologies and research tools, enabling others to access and re-use their data, and, especially, by publishing their findings with open access. Scientists have developed a number of methods for sharing the different stages of their research, and publishers are now enabling them to publish a wide range of their research outputs, from methodologies, to software tools, to data notes and case studies. But are these article types relevant in the arts & humanities? Does the way we conduct and publish our research allow for openness on the same basis? In this session Dr Harris-Birtill gives an introductory overview of open access publishing and the multi-award-winning scholarly publisher the Open Library of Humanities (OLH), covering the different types of open access currently available, the benefits and challenges facing open access today, and how OLH’s business model works, discussing what has been achieved to date.https://cassyni-user-files-prod.s3.amazonaws.com/LZCMU6MnUAqVWCNzPubZTk https://cassyni.com/events/5YA11WcQcaF86iwxpDqoZf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CWv79GG159RKswBTQMUjV8 https://cassyni.com/events/5YA11WcQcaF86iwxpDqoZf?videoPreview=1 Sexual Health Knows No Borders—So Why Are Migrant Women Left Behind?nohttps://cassyni.com/events/5YA11WcQcaF86iwxpDqoZf?videoPreview=12025-02-16T01:00:00+00:00100.04Women's HealthSexual health is a critical yet often neglected aspect of migrant and refugee women’s well-being. Existing healthcare systems prioritize survival over dignity, failing to address issues like sexual dysfunction, pleasure, and autonomy. This editorial highlights the need for structural changes, including culturally sensitive healthcare, inclusive education, and policies that affirm sexual health as a human right for all women, regardless of migration statushttps://cassyni-user-files-prod.s3.amazonaws.com/CWv79GG159RKswBTQMUjV8 https://cassyni.com/slides/outline/QoUBvoMm8nmmh1T5wCGHAm https://cassyni.com/events/QoUBvoMm8nmmh1T5wCGHAm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/ERuHMykEGbapJAtUhqVrhC https://cassyni.com/events/QoUBvoMm8nmmh1T5wCGHAm?videoPreview=1 The Impact of Digital Strategies to Boost Cervical Screening Uptake in Primary Carenohttps://cassyni.com/events/QoUBvoMm8nmmh1T5wCGHAm?videoPreview=12025-04-14T11:00:00+00:00522.04Sage PublishingIntroduction Cervical cancer is largely preventable through regular screening, yet uptake in the UK remains below national targets, particularly among harder-to-reach groups. Despite national efforts, barriers such as fear, embarrassment, and low health literacy persist, hindering participation. This retrospective review assesses the impact of providing information and education about cervical screening (CS) to hard-to-reach populations, aiming to increase CS uptake in line with the national target of 80% coverage. Methods Using a multidisciplinary team approach, women who had previously missed screenings were identified through electronic records. Remote interventions, including educational videos delivered via email and SMS, as well as an online booking system, were implemented to provide accessible information and flexible appointment options. These interventions aimed to address common barriers and encourage informed participation. Results Over a three-month period, screening rates increased significantly across both target age groups. Uptake among women aged 25–49 rose from 77% to 80.5%, while rates among women aged 50–64 improved from 81% to 97%. Conclusion This review highlights the potential effectiveness of remote communication tools in increasing cervical screening participation, particularly among populations historically less likely to engage. Integrating digital resources into routine practice also has the potential to reduce administrative burdens, enhance patient education, and increase the accessibility of screening. By addressing key barriers and offering flexible booking options, primary care clinics can enhance screening uptake, support earlier cervical cancer detection, and ultimately improve patient outcomes.https://cassyni-user-files-prod.s3.amazonaws.com/ERuHMykEGbapJAtUhqVrhC https://cassyni.com/slides/outline/Lqs1qtTGaiSihsxYHizGsP https://cassyni.com/events/Lqs1qtTGaiSihsxYHizGsP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FEPN7dVGCw9Py3pjD5idQr https://cassyni.com/events/Lqs1qtTGaiSihsxYHizGsP?videoPreview=1 Improving Clinical Pharmacist Performance in Oncology Care Through Education on Pharmaceutical Care Plans Documentation: A Pre-Post Interventional Studynohttps://cassyni.com/events/Lqs1qtTGaiSihsxYHizGsP?videoPreview=12025-04-26T14:00:00+00:00573.16Sage PublishingIntroduction Clinical pharmacists are vital in oncology care involved in optimizing pharmaceutical care plans(PCPs). Their involvement in medication management, and accurate documentation assists for care of patients with cancer. **Objective** This study aims to evaluates the impact of a targeted educational intervention for clinical pharmacists on both the quantity and quality of PCP documentation, providing insights into optimizing pharmaceutical care within an oncology setting. **Methods** A descriptive pre-post study was done at Shaukat Khanum Memorial Cancer Hospital & Research Centre, Lahore. Data on admitted patients' PCPs from November 2023 to March 2024 was collected from the Hospital Information System. PCP documentation was evaluated following the educational intervention on clinical pharmacy staff where the improvement in the documentation among specialties section was analyzed using a one-tailed t-test. **Results** The study assessed a total of 120 patients during the pre-intervention phase and 382 patients post-intervention. In the pre-intervention phase, the mean ± SD age of patients was 36.1 ± 20.1 years, with males constituting 57.5% and females 42.5%. Post-intervention, the mean ± SD age slightly increased to 37.3 ± 20.7 years, with a similar gender distribution of 58.9% males and 41.1% females. The intervention significantly increased the number of PCPs from 130 in the pre-intervention phase to 516 in the post-intervention phase particularly in Adult Oncology (p-value = 0.0115) and Palliative Care (p-value =0.0095). The ratio of PCPs to patient admissions improved markedly from 1:13 to 1:50, indicating a substantial enhancement in the documentation and management of PCPs. **Conclusion** The study demonstrates that structured educational interventions significantly enhance the documentation of PCPs by clinical pharmacists. By integrating targeted training with continuous reinforcement strategies, healthcare institutions can optimize pharmaceutical care processes, improve interdisciplinary collaboration, and ultimately enhance patient safety in oncology settings. https://cassyni-user-files-prod.s3.amazonaws.com/FEPN7dVGCw9Py3pjD5idQr https://cassyni.com/slides/outline/RHhTG3GzXqRyAXiLCNkr1s https://cassyni.com/events/RHhTG3GzXqRyAXiLCNkr1s/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HD2G3Ztpb8DJhtxc9Ez422 https://cassyni.com/events/RHhTG3GzXqRyAXiLCNkr1s?videoPreview=1 Predisposition to hematopoietic malignancies by deleterious germline CHEK2 variantsnohttps://cassyni.com/events/RHhTG3GzXqRyAXiLCNkr1s?videoPreview=12025-05-28T16:00:00+00:00976.28LeukemiaThe role of germline CHEK2 variants in hematopoietic malignancies (HMs) is poorly understood. We examined pathogenic/likely pathogenic (P/LP) CHEK2 variants in patients with hereditary HMs (HHMs), a solid tumor risk cohort, public datasets, and a knock-in mouse model. In the HHM cohort, 57 probands had germline P/LP CHEK2 variants, mostly p.I157T (53%, 30/57). Among CHEK2 p.I157T carriers, 43% (19/44) had myeloid malignancies, 32% (14/44) had lymphoid malignancies, and 2% (1/44) had both. Among those with other germline P/LP CHEK2 alleles, 36% (13/36) had myeloid malignancies, 28% (10/36) had lymphoid malignancies, and 6% (2/36) had both. CHEK2 p.I157T was enriched in HM patients (OR 6.44, 95%CI 3.68-10.73, P<0.001). In a solid tumor risk cohort, 36% (15/42) of CHEK2 p.I157T patients had a HM family history. A genome wide association study showed enrichment of CHEK2 loss-of-function variants with myeloid leukemia (P=5.78e-7). In public acute myeloid leukemia (AML) datasets, 1% (16/1348) of patients had P/LP CHEK2 variants. In a public myelodysplastic neoplasms (MDS) dataset, 2% (5/214) had P/LP CHEK2 variants. Chek2 p.I161T mice, homologous to human p.I157T, had worse survival as heterozygotes (P=0.037) or homozygotes (P=0.005), with fewer Lin-CD34+ and Lin-cKit+ cells. Our data suggests P/LP CHEK2 variants are a HHM risk allele.https://cassyni-user-files-prod.s3.amazonaws.com/HD2G3Ztpb8DJhtxc9Ez422 https://cassyni.com/events/FuNyP3z2C8uRFTfrndvuTb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KJd8PigD9wVCSJ2Eru445t https://cassyni.com/events/Xh9Wrteo9ACrRkr3zitdgq/seminar/qa https://cassyni.com/slides/outline/Xh9Wrteo9ACrRkr3zitdgq https://cassyni.com/events/Xh9Wrteo9ACrRkr3zitdgq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CSg4KugtasE1Sobq3qVhsC https://cassyni.com/events/Xh9Wrteo9ACrRkr3zitdgq?videoPreview=1 Physics-based super-resolved simulation of 3D elastic wave propagation adopting scalable Diffusion Transformer nohttps://cassyni.com/events/Xh9Wrteo9ACrRkr3zitdgq?videoPreview=12025-11-19T15:00:00+00:001965.96Computer Physics CommunicationsIn this study, we develop a Diffusion Transformer (referred as to DiT1D) for synthesizing realistic earthquake time histories. The DiT1D generates realistic broadband accelerograms (0-30 Hz resolution), constrained at low frequency by 3-dimensional (3D) elastodynamics numerical simulations, ensuring the fulfillment of the minimum observable physics. The DiT1D architecture, successfully adopted in super-resolution image generation, is trained on recorded single-station 3-components (3C) accelerograms. Thanks to Multi-Head Cross-Attention (MHCA) layers, we guide the DiT1D inference by enforcing the low-frequency part of the accelerogram spectrum into it. The DiT1D learns the low-to-high frequency map from the recorded accelerograms, duly normalized, and successfully transfer it to synthetic time histories. The latter are low-frequency by nature, because of the lack of knowledge on the underground structure of the Earth, demanded to fully calibrate the numerical model. We developed a CNN-LSTM lightweight network in conjunction with the DiT1D, so to predict the peak amplitude of the broadband signal from its low-pass-filtered counterpart, and rescale the normalized accelerograms rendered by the DiT1D. Despite the DiT1D being agnostic to any earthquake event peculiarities (magnitude, site conditions, etc.), it showcases remarkable zero-shot prediction realism when applied to the output of validated earthquake simulations. The generated time histories are viable input accelerograms for earthquake-resistant structural design and the pre-trained DiT1D holds a huge potential to integrate full-scale fault-to-structure digital twins of earthquake-prone regions. The pretrained DiT1D is available at https://github.com/HugoGabrielidis16/Seismic_DiT1D.https://cassyni-user-files-prod.s3.amazonaws.com/CSg4KugtasE1Sobq3qVhsC https://cassyni.com/events/PnSNkQ7mHWECWA5p8eyjvd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UjKAJBF4cLVYSuYEtuL84W https://cassyni.com/events/YBWtmH9TZ1VgdfbJgk5Qh3/seminar/qa https://cassyni.com/slides/outline/YBWtmH9TZ1VgdfbJgk5Qh3 https://cassyni.com/events/YBWtmH9TZ1VgdfbJgk5Qh3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CfLnFgBw9i5KYEsfVfUKC2 https://cassyni.com/events/YBWtmH9TZ1VgdfbJgk5Qh3?videoPreview=1 SDG14: El Biotop: A New Horizon in Artificial Reefs and Marine Restoration strategies in the Mediterranean Seanohttps://cassyni.com/events/YBWtmH9TZ1VgdfbJgk5Qh3?videoPreview=12026-06-30T15:00:00+00:004468.16Springer Nature Sustainable Development Goals ProgrammeWith the aim of establishing a strategic point for ecological restoration in the Mediterranean, El Biotop was created, now recognized as the world’s largest artificial calcareous reef. This project represents a new form of blue infrastructure, carrying significant potential in the global efforts for marine conservation, restoration, and resilience. The Biotop reef stands as an unprecedented HCAR model. Its distinctive structure, formed from 37,000 tones of calcium carbonate rocks (CaCO3) extracted from nearby Miocene-era marine fossil deposits stands as an innovative model on strategic planning for coastal management. Functionally and structurally, it sets itself apart from previous Ars models. Over the course of one-year, extensive monitoring has analyzed the colonization processes, species attraction and productivity, and its potential as a Marine Reserve and usage as a critical habitat for commercial and vulnerable species. Remarkably, in just one year, over 250 species have been recorded on the reef, including 11 threatened species, 9 protected species, 55 commercially relevant species, and over 50 bioindicators. Among the most notable achievements is the natural growth of gorgonian corals within just 15 months, highlighting the potential for passive restoration strategies to play a larger role in future conservation efforts. This project has spurred numerous collaborative research lines with universities and research centers, focusing on topics such as active restoration and gorgonian demography, ocean sensing, fishery monitoring, and species recovery potential. Natural Art Reef (NAR) is a non-profit association whose aims include the construction and implementation of organic and ecological artificial reef structures for the promotion of tourism, research, conservation and dissemination activities. The association offers environmental, cultural and maritime action solutions in which it develops studies, monitoring and scientific evaluations, as well as dissemination and social awareness projects. NAR has extensive experience in the Mediterranean being a pioneer in the implementation of calcium carbonate structures and in the construction of El Biotop, the first large rocky reef in the world.https://cassyni-user-files-prod.s3.amazonaws.com/CfLnFgBw9i5KYEsfVfUKC2 https://cassyni.com/slides/outline/6zg4KTGnPYfMcc4E7L2rxD https://cassyni.com/events/6zg4KTGnPYfMcc4E7L2rxD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QZ15T9B4asG9cCYKMoENw8 https://cassyni.com/events/6zg4KTGnPYfMcc4E7L2rxD?videoPreview=1 Adverse Health Consequences of Poor Air Quality in Nepal: a wake-up callnohttps://cassyni.com/events/6zg4KTGnPYfMcc4E7L2rxD?videoPreview=12025-08-28T11:05:14+00:00437.32Sage PublishingAuthors: Nabin Pathak, Shreya Dhungana, Prashant Bidari, Sunil Shrestha, Meghnath Dhimal Abstract: Literature shows that poor air quality index (AQI) is associated with several adverse health impacts, such as asthma, chronic obstructive pulmonary disease, diabetes mellitus, tuberculosis, cancer, pneumonia, cataracts, heart diseases and mental health disorders. Nepal, one of the lower middle-income countries, has become vulnerable to adverse health impacts due to poor AQI over time. The capital city of Nepal, Kathmandu, is frequently placed under one of the most polluted city by IQAir. As such, this statement marks a caution for policy makers and public to be aware of the future effects of prolonged exposure to air pollution and highlights its causative factors. To solve this burgeoning issue because of the significant rise in urbanization and population growth, mitigation strategies such as creating awareness, reducing veichular emission, reducing forest fires, creating and identifying vulnerability maps risk zones for forest fires, switching to electronic vehicles and personal intervention such as staying indoors and reducing physical outdoor activity, wearing face masks must be focused and given priority. Although our study is limited in its methodology and findings, it helps establish a policy base to underscore a need for longitudinal cohort studies to generate further evidence pertaining to air quality levels and health impacts in the Nepalese population. https://cassyni-user-files-prod.s3.amazonaws.com/QZ15T9B4asG9cCYKMoENw8 https://cassyni.com/events/AwfXtWqn5gcRPEDwUJf9Mw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UuKQcg2txj4ECtLkWXdMJN https://cassyni.com/slides/outline/FPkaLLJUf3vqkR9ZdFjrwo https://cassyni.com/events/FPkaLLJUf3vqkR9ZdFjrwo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RmjPeKkU42rkbyXoVhZPv6 https://cassyni.com/events/FPkaLLJUf3vqkR9ZdFjrwo?videoPreview=1 Quantum complexity in gravity, quantum field theory, and quantum information sciencenohttps://cassyni.com/events/FPkaLLJUf3vqkR9ZdFjrwo?videoPreview=12026-01-07T10:25:40+00:004326.96Physics ReportsQuantum complexity quantifies the difficulty of preparing a state or implementing a unitary transformation with limited resources. Applications range from quantum computation to condensed matter physics and quantum gravity. We seek to bridge the approaches of these fields, which define and study complexity using different frameworks and tools. We describe several definitions of complexity, along with their key properties. In quantum information theory, we focus on complexity growth in random quantum circuits. In quantum many-body systems and quantum field theory (QFT), we discuss a geometric definition of complexity in terms of geodesics on the unitary group. In dynamical systems, we explore a definition of complexity in terms of state or operator spreading, as well as concepts from tensor-networks. We also outline applications to simple quantum systems, quantum many-body models, and QFTs including conformal field theories (CFTs). Finally, we explain the proposed relationship between complexity and gravitational observables within the holographic anti-de Sitter (AdS)/CFT correspondence.https://cassyni-user-files-prod.s3.amazonaws.com/RmjPeKkU42rkbyXoVhZPv6 https://cassyni.com/events/NJrf6XsiCpcMPhqYHGFEj7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/647wVAxroWaKmVWSM1w9Se https://cassyni.com/events/7zLMu1GMW9p3Y1TtktVPXj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8Jw7B3j87DKFyw6ZhpAmRg https://cassyni.com/slides/outline/DuSfi6fP6zE9WAPPLXGwA5 https://cassyni.com/events/DuSfi6fP6zE9WAPPLXGwA5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/T3ApP3seWrzNb8qC7ExQeS https://cassyni.com/events/DuSfi6fP6zE9WAPPLXGwA5?videoPreview=1 Principal Component Analysis and K-Means Clustering of Fuel-Air Mixing in Gas Turbine Combustorsnohttps://cassyni.com/events/DuSfi6fP6zE9WAPPLXGwA5?videoPreview=12026-02-14T17:00:00+00:002129.56Data-Centric Engineering JournalAs a direct consequence of liquid kerosene injection, aeroengine combustors may be categorized as non-premixed combustion systems, characterized by a swirl-stabilized and highly complex flow field. In addition to the flow of air through the fuel injector, there are a large number of other features through which oxidizer can enter the heat release region. These can have an impact on local fuel-air mixing, inducing strong spatial and temporal variations in stoichiometry, thereby affecting emissions and combustion system performance. This paper discusses a novel statistical methodology, based on Principal Component Analysis (PCA) and K-means clustering, that aims to improve understanding of fuel-air mixing in realistic aeroengine combustors. The method is applied in a postprocessing step to data sampled from a Large Eddy Simulation (LES), where every chamber inflow has been tagged with a unique passive scalar, which allows it to be traced across space and time. PCA is used to construct a low-dimensional, visually interpretable representation of a spatially localized fuel-air mixing process, while K-means clustering is employed to produce an unsupervised discretization of the flow field into regions of similar fuel-air mixing characteristics. The proposed methodology is computationally inexpensive, and the easily interpretable outputs can help the combustion engineer make better informed decisions about combustor design.https://cassyni-user-files-prod.s3.amazonaws.com/T3ApP3seWrzNb8qC7ExQeS https://cassyni.com/slides/outline/TF2rJSgDARxfEZsxgGNQxu https://cassyni.com/events/TF2rJSgDARxfEZsxgGNQxu/abstract https://cassyni.com/events/TF2rJSgDARxfEZsxgGNQxu?videoPreview=1 Genetic assimilation and accommodation shape adaptation to heat stress in a splash pool copepodnohttps://cassyni.com/events/TF2rJSgDARxfEZsxgGNQxu?videoPreview=12026-05-02T17:00:00+00:001863.56Royal Society PublishingUnderstanding organismal responses to dynamic environments is becoming increasingly important in our rapidly changing world. Beyond genetic adaptation, plastic responses to the environment can alter phenotypes and fitness, ultimately driving evolution. However, the interaction between plasticity and adaptation during environmental change is complex and hard to measure in natural systems. Here, we used two populations of Tigriopus californicus copepods, a thermally tolerant southern population and a thermally sensitive northern population, to conduct a fully factorial, split-brood experiment where we exposed animals as larvae and adults to either a sublethal heat stress or control (no heat treatment) before measuring phenotypic plasticity of heat tolerance and gene expression plasticity patterns. We found that increased thermal tolerance across populations came at the expense of physiological plasticity and evolved through both higher baseline expression as well as increased gene expression plasticity of heat stress related genes. Importantly, we found evidence for plasticity-led evolution in this system, with the same set of genes contributing to long-term evolutionary changes across populations and to short-term physiological adjustments within populations providing insight into how these populations will adapt and respond to future environmental change. https://cassyni.com/events/KqLQipVDyvabZzPxstxBgy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3KbZRKRHHJnsZMyX6U3M6E https://cassyni.com/slides/outline/3XwUCG8uVpJatehUWRoQww https://cassyni.com/events/3XwUCG8uVpJatehUWRoQww/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5ga8X17bqg3ck6MFTRPiUE https://cassyni.com/events/3XwUCG8uVpJatehUWRoQww?videoPreview=1 Carrollian Geometry: The Language of Null Hypersurfacesnohttps://cassyni.com/events/3XwUCG8uVpJatehUWRoQww?videoPreview=12026-06-26T22:00:00+00:003075.04Physics ReportsCarrollian physics is emerging as a powerful geometric framework for the physics of lightlike surfaces — the places where radiation, horizons, and long-range interactions naturally reside. I will give an introduction to the basic concepts of Carrollian geometry and show how they capture the intrinsic structure of null hypersurfaces. Starting from an ambient spacetime, I will explain how Carrollian data are induced on a null manifold and how the standard geometric and dynamical equations of general relativity, from Gauss–Codazzi relations to Einstein’s equations, reorganize themselves in this language. The result is a new lens on null geometry, connecting spacetime dynamics to the universal physics of radiation.https://cassyni-user-files-prod.s3.amazonaws.com/5ga8X17bqg3ck6MFTRPiUE https://cassyni.com/events/6zWKdgBTyP6zk3TfMm1YPf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/MY7j4WdDWvtez51pJSSSdU https://cassyni.com/events/Mp1hFScywqaAhNfcmkVcmB/seminar/qa https://cassyni.com/events/Mp1hFScywqaAhNfcmkVcmB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/YXCyonC2gQaJxqXqLXboEe https://cassyni.com/events/CSAoKA65TGoHzfDgfYFxgD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VWTitL4CgrMBSrHZhPmoT4 https://cassyni.com/events/KqvV83JqSW2rdiSYuz48iq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Ufca3jpQjqyx16sLz6gcT8