https://cassyni.com/slides/outline/Abdi3juDhMNBSfKcbejnA1 https://cassyni.com/events/Abdi3juDhMNBSfKcbejnA1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/SDP2cDLjWHXEVmxUsF7UC6 https://cassyni.com/events/Abdi3juDhMNBSfKcbejnA1?videoPreview=1 Physics Informed Learning for Multiscale Dynamical Systemsnohttps://cassyni.com/events/Abdi3juDhMNBSfKcbejnA1?videoPreview=12021-05-14T14:00:00+00:004096.64AI Institute in Dynamic SystemsMost attempts at the interface of physical modeling and machine learning (ML) employ computationally-generated data in order to drive the various statistical discovery objectives. This enables a direct transfer and application of ML tools and techniques, but removes valuable structure, symmetries and invariances that were present in the model. In order to rediscover this structure, if at all possible, ML tools would need copious amounts of data. Even when big data is available, it is important to ensure that predictions produced by ML models trained on this data satisfy these constraints. Purely data-based, modern ML tools as those based on deep neural networks (DNN) provide rich representations for learning complex nonlinear functions, but lack robustness and fail when higher-level abstractions implied by the physical structure are needed to make predictions. We will discuss some aspects in the development of generative multiscale deep learning approaches incorporating known physical constraints as prior knowledge. Examples will be provided in the development of DNN surrogate models for multiscale stochastic PDEs, multi-fidelity DNN algorithms for fluid flows, integrating pre-trained VAE models with high-dimensional Bayesian multiscale inversion tasks, Koopman embedding in transformer models for prediction of dynamical systems, and deep generative modeling of molecular dynamics.https://cassyni-user-files-prod.s3.amazonaws.com/SDP2cDLjWHXEVmxUsF7UC6 https://cassyni.com/events/NwE7gyjqorpxmPi9TJsKqw/seminar/qa https://cassyni.com/slides/outline/NwE7gyjqorpxmPi9TJsKqw https://cassyni.com/events/NwE7gyjqorpxmPi9TJsKqw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6pajYFiBDjk9NVxM3TRo5Y https://cassyni.com/events/NwE7gyjqorpxmPi9TJsKqw?videoPreview=1 Attracting High Quality Submission through Collectionsnohttps://cassyni.com/events/NwE7gyjqorpxmPi9TJsKqw?videoPreview=12023-04-25T15:30:00+00:002595.52Topics at the heart of our communityThe impact of a collection can be higher than other papers in a journal. In this session, we’ll explore how collections can be leveraged towards greater impact for their journals more broadly, including attracting high quality submissions and increasing their journal’s visibility in the community.https://cassyni-user-files-prod.s3.amazonaws.com/6pajYFiBDjk9NVxM3TRo5Y https://cassyni.com/slides/outline/QupXsiKwZh3is6zNpGjGGV https://cassyni.com/events/QupXsiKwZh3is6zNpGjGGV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Y4XVGxSJ4Z1tVybHX5REJr https://cassyni.com/events/QupXsiKwZh3is6zNpGjGGV?videoPreview=1 The mechanisms of surface charge formation on polymers - Toward Triboelectric Generatorsnohttps://cassyni.com/events/QupXsiKwZh3is6zNpGjGGV?videoPreview=12023-01-10T13:00:00+00:003049.92Department of AeronauticsThe triboelectrification (TE) of polymers has gained a vast attention in field of mechanical energy harvesting and related application for powering microdevices and portable electronics. Numerous concepts of triboelectric generator (TG) devices have been demonstrated which exploits TE for harvesting mechanical energy. There are various sources of mechanical energy which can be harvested by TG including biomechanical movement, water drops, ambient noise, wind, and water waves. The performance of TG devices is governed by magnitude of surface charge, thus it is highly important to understand the mechanism of TE to develop materials which are tending to gain strong surface charge.https://cassyni-user-files-prod.s3.amazonaws.com/Y4XVGxSJ4Z1tVybHX5REJr https://cassyni.com/events/87mzJUL6e8DLTTRSSf3bJD/seminar/qa https://cassyni.com/slides/outline/87mzJUL6e8DLTTRSSf3bJD https://cassyni.com/events/87mzJUL6e8DLTTRSSf3bJD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EetvJu18p3vFjagUn6Vs7k https://cassyni.com/events/87mzJUL6e8DLTTRSSf3bJD?videoPreview=1 Scaling Laws for the Energy Transfer in Space Plasma Turbulencenohttps://cassyni.com/events/87mzJUL6e8DLTTRSSf3bJD?videoPreview=12023-04-18T14:00:00+00:004679.68Physics ReportsOne characteristic trait of space plasmas is the multi-scale dynamics resulting from non-linear transfers and conversions of various forms of energy. Routinely evidenced in a range from the large-scale solar structures down to the characteristic scales of ions and electrons, turbulence is a major cross-scale energy transfer mechanism in space plasmas. At intermediate scales, the fate of the energy in the outer space is mainly determined by the interplay of turbulent motions and propagating waves. More mechanisms are advocated to account for the transfer and conversion of energy, including magnetic reconnection, emission of radiation and particle energization, all contributing to make the dynamical state of solar and heliospheric plasmas difficult to predict. The characterization of the energy transfer in space plasmas benefited from numerous robotic missions. However, together with breakthrough technologies, novel theoretical developments and methodologies for the analysis of data played a crucial role in advancing our understanding of how energy is transferred across the scales in the space. In recent decades, several scaling laws were obtained providing effective ways to model the energy flux in turbulent plasmas. Under certain assumptions, these relations enabled to utilize reduced knowledge (in terms of degrees of freedom) of the fields from spacecraft observations to obtain direct estimates of the energy transfer rates (and not only) in the interplanetary space, also in the proximity of the Sun and planets. Starting from the first third-order exact law for the magnetohydrodynamics by Politano and Pouquet (1998), we present a detailed review of the main scaling laws for the energy transfer in plasma turbulence and their application, presenting theoretical, numerical and observational milestones of what has become one of the main approaches for the characterization of turbulent dynamics and energetics in space plasmas. Copyright permission for the seminar banner granted by [ESA/ATG medialab](https://www.esa.int/ESA_Multimedia/Images/2020/06/Solar_Orbiter_reaches_first_perihelion). https://cassyni-user-files-prod.s3.amazonaws.com/EetvJu18p3vFjagUn6Vs7k https://cassyni.com/events/Cj9mXndu5PeWtE3gbYw2M/seminar/qa https://cassyni.com/slides/outline/Cj9mXndu5PeWtE3gbYw2M https://cassyni.com/events/Cj9mXndu5PeWtE3gbYw2M/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9DySHn2hrkHKsxPDWR7irr https://cassyni.com/events/Cj9mXndu5PeWtE3gbYw2M?videoPreview=1 Remediation of Pollutants using Ultrasound Induced Cavitation: “Nanostars in a Jar”nohttps://cassyni.com/events/Cj9mXndu5PeWtE3gbYw2M?videoPreview=12023-12-21T10:00:00+00:003965.08ElsevierWastewater treatment is becoming a worldwide concern due to new and tighter environmental regulations, and the increasing need for fresh water for the exponentially growing population. Major contributing factors are the increase in the presence of emerging contaminants (EC) such as pharmaceuticals, pesticides, microplastics and industrial chemicals, and the ineffective removal of these ECs by existing wastewater treatment processes. Alternative methods such as ultrasound is been investigated as an advanced oxidation process to enhance degradation of ECs. Irradiation of ultrasound in solution can generate acoustic cavitation that leads to the creation of reactive free radicals and conditions to facilitate applications such as degradation of pollutants, synthesis of polymers as well as nanomaterials such as metal colloids, metal nano-composites and hollow shelled micro/nano-spheres. These ultrasonic effects stem from the creation of cavitation bubbles as the sound waves propagate through a liquid medium. Liken to “a star in a jar”, these cavitation bubbles can emit light (sonoluminescence) and undergo violent collapses to generate extreme temperatures (> 5000 k), pressures (> 1000 atm) and jet velocities (up to 120 m/s has been reported). It is these remarkable conditions which create the unusual physical and chemical effects that we observe. However, to capitalise on these effects, one needs to understand the mechanisms behind the physical and chemical conditions created, and the importance of solution and sonication conditions used. This presentation will provide fundamental background on the mechanism behind ultrasound enhanced degradation, importance of solution and sonication conditions, and some case studies on the application of ultrasound in degradation of emerging pollutants such as pharmaceuticals.https://cassyni-user-files-prod.s3.amazonaws.com/9DySHn2hrkHKsxPDWR7irr https://cassyni.com/slides/outline/LU3LgpXzRHuyNvyTMhLdth https://cassyni.com/events/LU3LgpXzRHuyNvyTMhLdth/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EUjuvL7qYW9kLURFHkNL7Y https://cassyni.com/events/LU3LgpXzRHuyNvyTMhLdth?videoPreview=1 Compute Over Data - Bringing Your Science to Where the Data Livesnohttps://cassyni.com/events/LU3LgpXzRHuyNvyTMhLdth?videoPreview=12022-12-12T17:00:00+00:003412.6DeSci FoundationAs sources of information grow ever larger and more distributed, scientists will have to move to the new world of executing complex jobs where the data lives. In this talk, we will be covering what this will look like in the future, and options for how to take advantage of, rather than being overwhelmed, by this opportunity.https://cassyni-user-files-prod.s3.amazonaws.com/EUjuvL7qYW9kLURFHkNL7Y https://cassyni.com/slides/outline/XLJdhrmY5N6SuCoUyEaKqX https://cassyni.com/events/XLJdhrmY5N6SuCoUyEaKqX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/C4gsMMuScsVLmeXiiebMUr https://cassyni.com/events/GWrWKMMnudUpbGWmxakbHo/seminar/qa https://cassyni.com/slides/outline/GWrWKMMnudUpbGWmxakbHo https://cassyni.com/events/GWrWKMMnudUpbGWmxakbHo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DbfzEJs3LNzShcuVuqvU1C https://cassyni.com/events/GWrWKMMnudUpbGWmxakbHo?videoPreview=1 The future of peer review - Royal Society Publishingnohttps://cassyni.com/events/GWrWKMMnudUpbGWmxakbHo?videoPreview=12023-09-25T14:00:00+00:003552.28Royal Society PublishingIn this webinar, two members of the Proceedings B editorial board (Preprint/Senior Editor Maurine Neiman and Associate Editor Stephanie Meirmans) will be joined by a published author in the journal (Kathleen Grogan) to explore trends in peer review and how they see peer review evolving with time. Together with Andrew Dunn (Senior Publishing Editor for Royal Society Open Science), who will chair the discussion, this webinar will examine issues such as transparency in peer review, the key influences driving change, and how matters such as equity, diversity and inclusivity can be most effectively addressed to ensure a better future for peer review.https://cassyni-user-files-prod.s3.amazonaws.com/DbfzEJs3LNzShcuVuqvU1C https://cassyni.com/events/UNJWyEpqqB4zxHRaj11o6d/seminar/qa https://cassyni.com/slides/outline/UNJWyEpqqB4zxHRaj11o6d https://cassyni.com/events/UNJWyEpqqB4zxHRaj11o6d/abstract https://cassyni-user-files-prod.s3.amazonaws.com/pXZuCsg57kyN2xZ9eVucr https://cassyni.com/events/UNJWyEpqqB4zxHRaj11o6d?videoPreview=1 LALS staff seminar 2023nohttps://cassyni.com/events/UNJWyEpqqB4zxHRaj11o6d?videoPreview=12023-03-31T03:10:00+00:002817.84Linguistics and Applied Language StudiesFollowing in the very competent footsteps of the recent LALS PhD student seminar, this Friday’s seminar features LALS staff. Each staff member has two minutes and two slides to efficiently and expertly explain their current research project. Come along and hear about the breadth and depth of linguistics research in the School! Physical location MYLT 220https://cassyni-user-files-prod.s3.amazonaws.com/pXZuCsg57kyN2xZ9eVucr https://cassyni.com/events/7dDFbgEEQkSNYz39qZPzbP/seminar/qa https://cassyni.com/slides/outline/7dDFbgEEQkSNYz39qZPzbP https://cassyni.com/events/7dDFbgEEQkSNYz39qZPzbP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/33NyUZz2XmA1CnGhFYrN4e https://cassyni.com/events/7dDFbgEEQkSNYz39qZPzbP?videoPreview=1 Air cavity deformation by single jointed diver model entry bodies, An experimental apparatus for generating homogeneous isotropic turbulencenohttps://cassyni.com/events/7dDFbgEEQkSNYz39qZPzbP?videoPreview=12024-01-09T15:00:00+00:003264.44Experiments in FluidsCompetitive divers are able to attain much higher scores when they perform a splash-less entry. To achieve this goal, they use the “rip” entry maneuver where they roll their body forward immediately after impact. This dynamic shape change after impact separates them from previously studied entry bodies. An experimental study of a geometrically simplified hinged diver model is presented. The results for five different hinged models are reported. Geometric and hinge stiffness changes are used to identify the most important aspects of the maneuver. The trajectory of these models after impact and the estimated size of the entrained air cavity are reported. The models that deform the fastest also have the largest final estimated air cavity. A non-dimensional time based on the time to complete deformation is found to collapse the estimated size of the air cavity for all models that deform before the trailing air cavity collapses. Fixed models are introduced to compare the hinged models to non-deforming entry bodies. The hinged models are found to have between $42\%$ and $154\%$ larger estimated air cavities during the final measurement than their fixed counterpart. At the moment of deep seal, two distinct air cavities are formed: one that connects to the atmosphere above the pool that has smooth walls and a lower cavity largely composed of small bubbles. This composition is analogous to observations of competitive divers. Entry bodies that deform are found to significantly change the shape and formation of the air cavity. An experimental apparatus using synthetic jets to generate zero mean flow homogeneous isotropic turbulence (HIT) in the center of a cubic water tank is presented. Pumps drive jets at the corners and midpoints of the tank edges, producing center- facing flow to generate turbulence. The array of synthetic jets is controlled by a random forcing algorithm (Variano et al. in Exp Fluids 37:613–615, 2004) to optimize generation of turbulence while minimizing mean and secondary flows. We explore different combinations of mean percentage of jets on, 𝛷on, mean on-time, Ton, and pump outlet velocity, VP, to determine their respective roles in turbulence generation. Particle image velocimetry (PIV) and acoustic Doppler velocimetry (ADV) are used to measure the velocity in the central isotropic region of the tank to determine turbulence statistics including mean velocities, mean flow strength, turbulent kinetic energy, spectra, integral scales, dissipation rates, Kolmogorov scales, Taylor microscales, and the Taylor-scale Reynolds number. We identified a range of input parameters to vary energy and length scales of the flow while maintaining homogeneity and isotropy in the central core of the facility. Magnitudes of the Taylor- scale Reynolds number ranged from 68 to 176 in the apparatus. Negligible mean recirculations were found, with mean flow strength values ranging from 1.26 to 2.99%, while ratios of root mean square turbulent velocities remained between 0.93 and 0.98, indicating a high degree of isotropy.https://cassyni-user-files-prod.s3.amazonaws.com/33NyUZz2XmA1CnGhFYrN4e https://cassyni.com/slides/outline/4Ag2GthZLYZjXHjbBu234Z https://cassyni.com/events/4Ag2GthZLYZjXHjbBu234Z/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BewEgB9pK2Y7sQbLcWJzLv https://cassyni.com/events/4Ag2GthZLYZjXHjbBu234Z?videoPreview=1 On Micropolar Elastic Foundations and Architected Interfacesnohttps://cassyni.com/events/4Ag2GthZLYZjXHjbBu234Z?videoPreview=12023-11-21T14:00:00+00:003453.0MetaMATWe will tackle the task of modelling heterogeneous and architected materials, necessitating advanced homogenisation techniques. In simplifying this challenge, we leverage micropolar elasticity. Simultaneously, elastic foundation theory is widely applied in fracture mechanics and delamination analysis of composite materials. The objective is to seamlessly integrate these frameworks, refining elastic foundation theory to accommodate materials exhibiting micropolar behaviour. Our elastic foundation theory for micropolar materials employs a stress potentials formulation, leading to closed-form solutions for stress and couple stress reactions, including the associated restoring stiffness. Additionally, we delve into the mechanical properties of conceptual structural adhesive joints, where the adhesive function is assumed by an architected interface. Diverging from isotropic interfaces, architected interfaces exert control over properties through tailored microstructures. To augment existing theoretical frameworks, we introduce our elastic foundation theory, encompassing emerging micromechanical effects. Illustrating how characteristic lengths govern the Mode I fracture behaviour of architected interfaces, we assert control over the fracture process zone size. Our findings, validated through numerical simulations, underscore the effectiveness of the proposed method.https://cassyni-user-files-prod.s3.amazonaws.com/BewEgB9pK2Y7sQbLcWJzLv https://cassyni.com/slides/outline/QRHRHYjxjgCD3njA18fjWd https://cassyni.com/events/QRHRHYjxjgCD3njA18fjWd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LMqPsR8rnqMYrQyJ6zE5K4 https://cassyni.com/events/QRHRHYjxjgCD3njA18fjWd?videoPreview=1 Convective boundary mixing and wave generation in the cores of massive starsnohttps://cassyni.com/events/QRHRHYjxjgCD3njA18fjWd?videoPreview=12022-11-10T12:00:00+00:003153.12Leeds Institute for Fluid DynamicsNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/LMqPsR8rnqMYrQyJ6zE5K4 https://cassyni.com/events/KUoNpiGiM6fBeh1ozexjnV/seminar/qa https://cassyni.com/slides/outline/KUoNpiGiM6fBeh1ozexjnV https://cassyni.com/events/KUoNpiGiM6fBeh1ozexjnV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/L5xv4VxfV2R5PTicBVwfaW https://cassyni.com/events/KUoNpiGiM6fBeh1ozexjnV?videoPreview=1 From molecular mechanisms to ecosystems, and backnohttps://cassyni.com/events/KUoNpiGiM6fBeh1ozexjnV?videoPreview=12023-12-14T15:00:00+00:003991.52Journal of Biological PhysicsAround eighty years of quantitative biology, combined with physical principles, now allow us to probe the details of living systems across many layers of organization. Molecular mechanisms, which regulate cellular expression levels, provide a rich field to study how cells respond to environmental stress and regulate their growth in changing environments. The dynamics of cellular populations outline the principles by which these mechanisms are selected and maintained. More complex ecological structures anchor multi-species interactions that can reshape the evolutionary landscape to include stable coexistence. However, each isolated layer carries its own set of rules; their application oftentimes leads to contradictory phenomena. In this talk I will discuss some of my recent and ongoing research that ties together the physics of living systems across different layers of complexity. https://cassyni-user-files-prod.s3.amazonaws.com/L5xv4VxfV2R5PTicBVwfaW https://cassyni.com/slides/outline/Xq1UyoSqKYW3YNFcy1XTvd https://cassyni.com/events/Xq1UyoSqKYW3YNFcy1XTvd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HeKgd8yMcakXZPMDkR6x4E https://cassyni.com/events/Xq1UyoSqKYW3YNFcy1XTvd?videoPreview=1 The Aerodynamics of Cricket Ball Swingnohttps://cassyni.com/events/Xq1UyoSqKYW3YNFcy1XTvd?videoPreview=12023-05-19T12:00:00+00:003327.16UK Fluids NetworkSwing bowling in the sport of cricket allows fast bowlers to curve the ball through the air at speeds up to 100 miles per hour. Cricket ball swing is viewed as a fickle, mysterious phenomenon by players, pundits and fans, with numerous theories and anecdotes which attempt to explain the optimal technique and conditions for swing. Our study was funded by the England and Wales Cricket Board (ECB) to investigate the aerodynamic origins of the skill, and identify the key factors which affect how much a ball will swing. The project used wind tunnel experiments at the Whittle Laboratory to measure the forces on real cricket balls, and infrared imaging technology to visualise boundary layer properties. This talk gives an overview of cricket ball swing physics and presents a statistical model for new ball swing that can be used to predict outcomes in professional cricket.https://cassyni-user-files-prod.s3.amazonaws.com/HeKgd8yMcakXZPMDkR6x4E https://cassyni.com/events/SPsqUHL4VWQy9W1PN6XfwB/seminar/qa https://cassyni.com/slides/outline/SPsqUHL4VWQy9W1PN6XfwB https://cassyni.com/events/SPsqUHL4VWQy9W1PN6XfwB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KZYcEwnzDHKPzVze9jycCN https://cassyni.com/events/SPsqUHL4VWQy9W1PN6XfwB?videoPreview=1 Evaluation of Care Cascade Outcomes for Patients with Gestational Diabetes Mellitus in a Specialist Supported Primary Care Model at a Community Health Center in Rhode Islandnohttps://cassyni.com/events/SPsqUHL4VWQy9W1PN6XfwB?videoPreview=12024-06-27T20:00:00+00:003499.12Family MedicineLearning Objectives: 1. Describe the burden of gestational diabetes mellitus (GDM) in an underserved setting in Rhode Island  2. Apply a care cascade framework to management of GDM in a specialist supported model of care  3. Use the care cascade framework to identify areas for improvement in management of GDM in an underserved setting in Rhode Island. https://cassyni-user-files-prod.s3.amazonaws.com/KZYcEwnzDHKPzVze9jycCN https://cassyni.com/slides/outline/C55K8TZqmEMPqLFZwszjem https://cassyni.com/events/C55K8TZqmEMPqLFZwszjem/abstract https://cassyni-user-files-prod.s3.amazonaws.com/xaFKbktAfy4ZDc2YyFGjp https://cassyni.com/events/C55K8TZqmEMPqLFZwszjem?videoPreview=1 Barriers and facilitators of Hispanic/Latino parents caregiving for a childhood cancer survivor: a qualitative studynohttps://cassyni.com/events/C55K8TZqmEMPqLFZwszjem?videoPreview=12024-12-19T19:00:00+00:003115.24Center for Cancer TrainingWe extend previous research on Hispanic/Latino caregiver experiences by exploring in-depth the perceived barriers and facilitators of parents in a safety-net clinic who are the primary caregivers throughout their child’s cancer journey. While there have been studies published on Hispanic/Latino caregivers of older adults, there has been little published on identifying the barriers and facilitators of caregiving experiences of parents. Given the intersecting complexities of this safety-net children’s clinic in Los Angeles, which serves primarily Hispanic, recently immigrated, Spanish-speaking, and Medicaid population, it is important to assess whether this vulnerable population has unique barriers and facilitators from previously published literature. Semi-structured phone interviews were conducted among 15 Hispanic/Latino parents caring for their child who was diagnosed with cancer. All interviews were conducted in English or Spanish based on the participant’s language preference. The interviews were recorded using a digital audio device and transcribed by a bilingual professional transcription service. To conserve the meaning of the interviews, they were transcribed and analyzed in the language in which they were conducted. Two bilingual coders independently reviewed transcripts coded them following reflexive thematic analysis and using elements of grounded theory methodology on Dedoose. This study revealed that multilevel factors impact Hispanic/Latino parents’ cancer care management. At the individual level, the magnitude of the caregiving responsibility acted as a barrier, while parents' self-described “relationship with God” acted as a facilitator. Interpersonal relationships, including familial flexibility and fluid roles in relation to caregiving and a positive relationship with the medical care team, were facilitators for caregivers. However, others' perceptions or misconceptions of their child’s illness were a barrier to caregiving. At the organizational and policy level, external financial resources and assistance navigating the application process were beneficial for parents. While issues related to financial hardship and uncertain immigration and citizenship status resulted in caregiver distress and challenges navigating the healthcare system. These findings can guide recommendations to address caregiver burden for this at-risk population at various levels, including suggestions for the healthcare system and policy level.https://cassyni-user-files-prod.s3.amazonaws.com/xaFKbktAfy4ZDc2YyFGjp https://cassyni.com/slides/outline/NSaWeJ6KNQGumdBFrsaXad https://cassyni.com/events/NSaWeJ6KNQGumdBFrsaXad/abstract https://cassyni-user-files-prod.s3.amazonaws.com/98RLEV2Um9upxypJqTxdjL https://cassyni.com/events/NSaWeJ6KNQGumdBFrsaXad?videoPreview=1 Parallel time integration using Batched BLAS routinesnohttps://cassyni.com/events/NSaWeJ6KNQGumdBFrsaXad?videoPreview=12023-06-20T15:00:00+00:003380.96Computer Physics CommunicationsQuantum technologies have emerged as promising avenues for advancing various fields. The development of these technologies requires precise quantum control. To achieve this, the development of novel control schemes necessitates interactive supercomputing, fast optimization techniques, and advanced test and measurement equipment. In this talk, we delve into the realm of quantum control, with a focus on manipulating quantum systems using Hamiltonians composed of drift and control terms over many time steps. This can be efficiently achieved in highly parallel on GPUs. The performance boost is particularly prominent for small to medium-sized quantum systems, which represent the majority of systems currently under experimental investigation. Our scheme, called PARAlellized Matrix Exponentiation for Numerical Time evolution (PARAMENT), leverages exponential integrators and relies solely on BatchedBLAS functions. This enables easy adaptation of PARAMENT to various applications.https://cassyni-user-files-prod.s3.amazonaws.com/98RLEV2Um9upxypJqTxdjL https://cassyni.com/slides/outline/HW6UBTd4ypjtNXTurPsXrV https://cassyni.com/events/HW6UBTd4ypjtNXTurPsXrV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RCdyTDo9xRtmkb6Txt1dzN https://cassyni.com/events/HW6UBTd4ypjtNXTurPsXrV?videoPreview=1 Sparse Nonlinear Dynamics Models with SINDy, Part 5: The Optimization Algorithmsnohttps://cassyni.com/events/HW6UBTd4ypjtNXTurPsXrV?videoPreview=12021-10-22T12:00:00+00:001107.36Brunton LabThis video discusses the various machine learning optimization schemes that may be used for the Sparse Identification of Nonlinear Dynamics (SINDy) algorithm. We discuss the LASSO sparse regression, sequential thresholded least squares (STLS), and the sparse relaxed regularized regression (SR3) algorithms. We also discuss how to enforce partially known physics, such as energy conservation in incompressible fluid flows, by constraining the sparse least squares regression. SLB acknowledges support from the National Science Foundation AI Institute in Dynamic Systems (grant number 2112085).https://cassyni-user-files-prod.s3.amazonaws.com/RCdyTDo9xRtmkb6Txt1dzN https://cassyni.com/events/VrJaLYoBxGakGChipkSFzd/seminar/qa https://cassyni.com/slides/outline/VrJaLYoBxGakGChipkSFzd https://cassyni.com/events/VrJaLYoBxGakGChipkSFzd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KEHUb2x9WazvBV6Lcng2GE https://cassyni.com/events/VrJaLYoBxGakGChipkSFzd?videoPreview=1 Consumer Retaliation as Political Activismnohttps://cassyni.com/events/VrJaLYoBxGakGChipkSFzd?videoPreview=12023-04-05T01:30:00+00:002576.2Department of MarketingAs firms increasingly take stances on divisive political issues, it is essential to understand how consumers’ political ideology influences reactions to such firms. This research examines the effect of U.S. consumers’ political ideology on their likelihood of punishing politically activist firms. We find that liberals are more likely than conservatives to punish politically opposing (vs. supporting) firms by spreading negative word of mouth, posting negative online reviews, complaining against them, and boycotting, because liberals believe these actions will have a stronger societal impact. We also test the mediating roles of moral enhancement motives and belief strength. These findings advance existing research on corporate political activism, political ideology, and consumer retaliation.https://cassyni-user-files-prod.s3.amazonaws.com/KEHUb2x9WazvBV6Lcng2GE https://cassyni.com/events/2geLnxDKp68G4bBCqk3oJm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8T4Hyw59aq3PpTwwe4e6Fg https://cassyni.com/events/2geLnxDKp68G4bBCqk3oJm?videoPreview=1 Characterisation of microstructural alterations in the brain after mild Traumatic Brain Injury with diffusion MRInohttps://cassyni.com/events/2geLnxDKp68G4bBCqk3oJm?videoPreview=12023-03-14T03:00:00+00:002611.56The Auckland Bioengineering InstituteTraumatic Brain Injury (TBI) results from sudden external physical trauma that causes damage to the brain, ranging from mild to severe forms of injury. Mild TBI or concussion presents difficulties in diagnosis due to subtle symptoms and subjective assessments. Advanced MRI techniques, particularly diffusion MRI, have emerged as promising tools for assessing patients with concussion in a quantitative manner. Thus, the present PhD project aims to characterize the microstructural changes in the brain following concussion using diffusion MRI in animal and human subjects. The results indicate that diffusion MRI is a promising technique for identifying microstructural damage due to head impacts. However, further longitudinal studies are needed to comprehend the mechanism of brain injury and its diagnosis and recovery process.https://cassyni-user-files-prod.s3.amazonaws.com/8T4Hyw59aq3PpTwwe4e6Fg https://cassyni.com/slides/outline/PRuLrHuFegJnarhfFQzJ29 https://cassyni.com/events/PRuLrHuFegJnarhfFQzJ29/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QsGbgP18qnCu4q3oetXMdg https://cassyni.com/events/PRuLrHuFegJnarhfFQzJ29?videoPreview=1 Integrated Finite Element Neural Network (I-FENN) for non-local continuum damage mechanicsnohttps://cassyni.com/events/PRuLrHuFegJnarhfFQzJ29?videoPreview=12023-05-31T11:00:00+00:001863.96Cassyni SeminarsIn this talk I will present I-FENN, a novel Integrated Finite Element Neural Network framework. The objective of I-FENN is to accelerate the numerical solution of non-linear, multi-physics, computational mechanics problems. The central idea is to deploy physics-informed machine learning algorithms directly in the finite element stiffness function, to approximate state variables of interest at a glance while ensuring the convergence of nonlinear solvers such as Newton Raphson. In this work, I-FENN is implemented in the continuum damage analysis of quasi-brittle materials. A new non-local gradient damage framework which operates at the cost of a local damage approach is established. At the offline stage, the pre-trained network receives as input the deformation state of each material point and learns to predict the corresponding nonlocal strain, as well as its derivative with respect to the local strain. Then, in the online stage, the network is integrated in the element stiffness definition and its outputs are used to construct the element Jacobian and residual vector. The latter process is carried out within the nonlinear solver until convergence is achieved. Therefore, the proposed method tackles the vital drawbacks of both the local and non-local gradient method, respectively being the mesh-dependence and the additional computational cost. A series of numerical examples showcases the feasibility, computational efficiency, generalization capability and robustness of I-FENN.https://cassyni-user-files-prod.s3.amazonaws.com/QsGbgP18qnCu4q3oetXMdg https://cassyni.com/events/KyN7XWNaaUS9ZAQ6bkcLVK/seminar/qa https://cassyni.com/slides/outline/KyN7XWNaaUS9ZAQ6bkcLVK https://cassyni.com/events/KyN7XWNaaUS9ZAQ6bkcLVK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9kbT8VSpV68feUrvQANeZt https://cassyni.com/events/KyN7XWNaaUS9ZAQ6bkcLVK?videoPreview=1 Sensing Physical Signals with Cytoskeletal Dynamicsnohttps://cassyni.com/events/KyN7XWNaaUS9ZAQ6bkcLVK?videoPreview=12023-05-18T14:00:00+00:003412.96Journal of Biological PhysicsThe dynamic assembly and disassembly of the cytoskeleton can create waves and oscillations that are critical to cell migration and other important cell behaviors. Chemical signals have been found to trigger and steer these waves, facilitating the guidance e.g. of immune cells to their target. Here we consider the role of these cytoskeletal dynamics in sensing the physical microenvironment. We demonstrate that cytoskeletal waves are directly involved in sensing both the microscopic texture of the surrounding, and local DC electric fields. In turn, these cytoskeletal dynamics drive signaling pathways, reversing the typical hierarchy where signals drive biomechanics.https://cassyni-user-files-prod.s3.amazonaws.com/9kbT8VSpV68feUrvQANeZt https://cassyni.com/events/WqdQYYc8EYcd5SE8DHr2S9/seminar/qa https://cassyni.com/events/WqdQYYc8EYcd5SE8DHr2S9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/13LEHgNGzxjt4Rm35u2Toc https://cassyni.com/events/WqdQYYc8EYcd5SE8DHr2S9?videoPreview=1 Enhancing Diver Capabilities with Dielectric Elastomer Sensorsnohttps://cassyni.com/events/WqdQYYc8EYcd5SE8DHr2S9?videoPreview=12023-05-30T04:00:00+00:003802.48The Auckland Bioengineering InstituteScuba diving allows for captivating exploration of the underwater realm, but it carries inherent risks such as decompression sickness, barotrauma, nitrogen narcosis and drowning. To ensure safety, divers must undergo thorough training, maintain their equipment properly, and practice the dive buddy protocol. This protocol is a set of guidelines and practices where scuba divers maintain constant communication through hand gestures, for monitoring each other's well-being, so as to provide immediate assistance in case of emergencies. However, underwater communication requires a clear line of sight, which is not always possible because of low visibility or lack of buddy attention. This can lead to buddy separation and increased risk. We can now communicate diver to diver in murky water through sensor-based motion capture of the hand. We have implemented dielectric elastomer sensors and an inertial measurement unit onto a dive glove for gesture capture. Our on-board electronics interprets gestures as discrete commands that can be relayed acoustically to a buddy or assistive robot and without requiring a line of sight. Furthermore, we are developing a smart wetsuit with integrated sensors for monitoring diver kinematics and physiology. We will be able to warn a buddy or the boat when problems arise. Our preliminary results suggest that we can also improve diver swimming technique for more efficient underwater locomotion. We are leading the way to better and safer diving through wearable technology! https://cassyni-user-files-prod.s3.amazonaws.com/13LEHgNGzxjt4Rm35u2Toc https://cassyni.com/slides/outline/3fyAzx2G6NA8sphcEHTZkH https://cassyni.com/events/3fyAzx2G6NA8sphcEHTZkH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/W3SaWKLfhvQk7n7bc78hve https://cassyni.com/events/3fyAzx2G6NA8sphcEHTZkH?videoPreview=1 Session 3: Lay Summary Toolkit (for Regulators, Funders, Journal Editors and Ethics Committee Members)nohttps://cassyni.com/events/3fyAzx2G6NA8sphcEHTZkH?videoPreview=12023-07-13T14:30:00+00:00763.6Institute for Cancer ResearchNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/W3SaWKLfhvQk7n7bc78hve https://cassyni.com/slides/outline/G2BHA3CP4ozzmVwRCe2HtR https://cassyni.com/events/G2BHA3CP4ozzmVwRCe2HtR/abstract https://cassyni-user-files-prod.s3.amazonaws.com/K4ofeVGHkfJ7vpFvYHqAdL https://cassyni.com/events/G2BHA3CP4ozzmVwRCe2HtR?videoPreview=1 Session 7nohttps://cassyni.com/events/G2BHA3CP4ozzmVwRCe2HtR?videoPreview=12023-07-04T03:45:00+00:004848.0New Phytologist Foundation Arabidopsis wild strain Bur-0 exhibits a temperature-sensitive phenotype known as irregularly impaired leaves (iil), which is caused by the expansion of GAA/TTC intronic trinucleotide repeat at the IIL1 locus. This results in transcriptional downregulation and similar to the intronic repeat expansion seen in the human genetic disorder Friedreich ataxia. By conducting a genetic suppressor screening, we identified FUG1, an uncharacterized SUMO protease that plays a key role in suppressing IIL1 expression and cause epigenetic silencing. Using Bio-chemical assays we discovered that FUG1 protease physically interacts with histone reader AL3, which in turn interacts with the PRC1 complex component LHP1 to cause a chromatin state switch from the active chromatin into inactive chromatin and promote gene silencing at the IIL1 locus. Our findings reveal novel genes and mechanisms of epigenetic silencing caused by expanded repeats which has implications not only for plants but also for human genetic disorders. Phytophthora capsici causes blight disease on over 50 crop species including tomato and pepper with annually multi-billion-dollar losses in crop production. P. capsici secret hundreds of effectors into a host cell to manipulate host immunity for successful colonization. However, even with the numerous studies on the roles of RXLR effectors, the molecular mechanisms of effector-induced necrotic host cell death remain elusive. Here, we report a novel P. capsici effector, Pc12, that causes cell death in the Solanaceae family without induction of defense-related gene expression and association with downstream signaling components of effector-triggered immunity. Pc12 enhances the colonization of P. capsici upon transient expression in Nicotiana benthamiana. Moreover, its homologs from other Phytophthora spp. having structural similarity with Pc12, especially in the C-termini, also induce cell death in N. benthamiana. Proteomics and microscopy assay reveal that Pc12 targets small GTPase Rab protein and perturbs vesicle trafficking between ER and Golgi apparatus, suggesting that the expression of Pc12 results in cell death under severe ER stress. Together, our results imply a new effector family functions in their pathogen growth via ER-mediated cell death. Plant roots interact in soil with pathogenic and beneficial bacteria. Structural (cutin, suberin, callose, lignin) and chemical (camalexin, glucosinolates, coumarins) defense components act as gatekeepers of microbial colonization. They have been thoroughly characterized by restricting pathogens colonization, however, their role in the assembly of a beneficial root microbiome or in the selection of commensals in the rhizosphere remains underexplored. Here, we studied the microbiome composition in 16 soil-grown Arabidopsis mutants affected in structural or chemical defense components and in different compartments (soil-rhizosphere-root) using 16S rRNA sequencing. Compared to wild type (WT) plants, cutin, suberin or the export of aliphatic glucosinolates mutants displayed significantly altered microbiomes in all compartments, while mutants for indolic glucosinolates or coumarin biosynthesis showed differences only in the rhizosphere. In general structural defenses played a higher role in the endosphere microbiome assembly while chemical defenses a higher role in the rhizosphere, showing that plant mechanisms of microbial selection are compartment specific. When looking at specific bacterial taxa changed in the root compartment compared to WT, most bacteria belonged to the Oxalobacteraceae, while other bacterial families had more mutant-specific patterns and will be targeted in future analyses. Ultimately, we envision to unravel novel plant mechanisms of microbiome recruitment. According to the Janzen-Connell hypothesis, conspecific negative density dependence (CNDD) maintains the exuberant plant diversity observed in tropical rainforests. Virola nobilis (syn. Virola surinamensis), a tree species native to Central America is a model species to study CNDD: Seedling mortality is high under conspecific V. nobilis trees, but toucans and monkeys disperse some seeds far from their mother tree, where survival is higher. Although it is generally accepted that natural enemies are responsible for CNDD in V. nobilis, it is unknown which microbes are driving it. Therefore, in this study we have characterized fungal pathogens infecting V. nobilis seedlings in Barro Colorado Island, in the Republic of Panama. We sowed seeds under conspecific trees and isolated fungi from symptomatic seedlings. Using infection assays in shade-houses we confirmed pathogenicity for several species of fungi in the Nectriaceae family. Isolates of Calonectria were among the most frequently isolated fungi and caused high mortality on V. nobilis seedlings. Additionally, we have characterized the fungal community using ITS metabarcoding from soil near V. nobilis trees and show that abundance of putative pathogens varies significantly between trees. In all, our results demonstrate the effect of several soil fungal species in seedling mortality and consequently the demographic dynamics of V. nobilis. Moreover, these results enable future studies to understand how plant-microbe interactions shape diversity in tropical forests.https://cassyni-user-files-prod.s3.amazonaws.com/K4ofeVGHkfJ7vpFvYHqAdL https://cassyni.com/events/Ab3deX5cEmuvNdhBbj2Vty/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4AcBsTCRA3PUywsZV418zA https://cassyni.com/slides/outline/B5hEhCj8gETyNQE5CAKJAH https://cassyni.com/events/B5hEhCj8gETyNQE5CAKJAH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8SWnUSAFoFPchajb23uS8e https://cassyni.com/events/B5hEhCj8gETyNQE5CAKJAH?videoPreview=1 Chaos in two cases of the full three-body problemnohttps://cassyni.com/events/B5hEhCj8gETyNQE5CAKJAH?videoPreview=12022-09-08T11:55:00+00:002055.36Celestial Mechanics and Dynamical AstronomyIn this talk we present two numerical studies of the three-body problem in the planar case. The first one concerns the motion of two bodies having equal mass (binary asteroids) and perturbed by a third one which is much heavier (a planet) and far away. The second one deals with 3 bodies with comparable masses focusing in the region of the unperturbed separatrix, which is complicated by a collision singularity; in both cases we define the model through a 4 degrees of freedom (dof) system, which turns out to be SO(2) invariant, then, introducing suitable coordinates in a rotating frame, we reduce this symmetry to get a 3 dof Hamiltonian. After a simply averaging, we reduce again the degrees of freedom to 2 and discuss in detail a 3-dimensional phase space through the use of first return mappings. We study the hyperbolic structure of the system and we show the existence of chaos, via the machinery of symbolic dynamics developed by Gidea, Zgliczynski. The work is joint with Jerome Daquin and Gabriella Pinzari.https://cassyni-user-files-prod.s3.amazonaws.com/8SWnUSAFoFPchajb23uS8e https://cassyni.com/slides/outline/Us4cUSXut5KxYGKvRYfh7b https://cassyni.com/events/Us4cUSXut5KxYGKvRYfh7b/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LinkkKe4B8BJZgvSKHDWHC https://cassyni.com/events/Us4cUSXut5KxYGKvRYfh7b?videoPreview=1 X-ray tomography study of granular materialsnohttps://cassyni.com/events/Us4cUSXut5KxYGKvRYfh7b?videoPreview=12021-04-13T12:00:00+00:004538.4Granular MatterTo develop a reasonable constitutive theory for dense granular materials, it is crucial to establish the connections between the microscopic and the macroscopic. This will first require the establishment of a statistical framework for these by nature out-of-equilibrium systems. Equally important is the identification of relevant microscopic processes which can be thermodynamically averaged to yield macroscopic responses. In this webinar, I will first try to test the validity of Edwards ensemble which is the only statistical mechanical framework conjectured to understand granular materials. Currently there exists no experimental validation of Edwards volume ensemble in three dimensions and the role played by friction has not been carefully investigated. We show one of our recent experimental work on this topic using X-ray tomography to investigate tapping-generated 3D granular packings. We validate Edwards volume ensemble as well as establish a granular version of thermodynamic zeroth law. We clarify the influence of friction on granular statistical mechanics as modifying the density of states. Upon the proof of the usefulness of the Edwards volume ensemble, we will then talk about one of its application on dense granular flows. Here we show in order to understand macroscopic response of granular materials upon shear, it is critical to consider structural evolutions on both particle and contact levels, thus differentiate them from ordinary disordered materials where only the particle level structures are important. By using defect concept similar to crystalline materials, we can then account for both volume fraction and shear force change during the whole shear cycle. We find that there exist two microscopic processes which tend to create and annihilate these defective structures and it is reasonable to conjecture that critical state corresponds the state when two processes reach balance.https://cassyni-user-files-prod.s3.amazonaws.com/LinkkKe4B8BJZgvSKHDWHC https://cassyni.com/events/TsmQP5Es1ADosWVvKaCNJh/seminar/qa https://cassyni.com/slides/outline/TsmQP5Es1ADosWVvKaCNJh https://cassyni.com/events/TsmQP5Es1ADosWVvKaCNJh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/S1tUDXvX9YZxLXdE2EmLiS https://cassyni.com/events/TsmQP5Es1ADosWVvKaCNJh?videoPreview=1 Modelling the Aviation Energy Transitionnohttps://cassyni.com/events/TsmQP5Es1ADosWVvKaCNJh?videoPreview=12023-11-29T16:00:00+00:003659.36Brahmal Vasudevan Institute for Sustainable AviationIn 2019, global aviation generated approximately 1 billion tonnes of CO2, which is almost three times the amount released by the entire UK economy. Warming from contrails is of similar magnitude, and thus greatly increases this sector’s climate impact. Reducing the aviation climate impact is particularly challenging due to the sector’s high growth rate and long-lived assets, as well as the importance of non-CO2 climate impacts and the absence of commercially available, scalable zero-carbon or carbon-neutral technology. Consequently, careful consideration of all mitigation options is required, that is, reducing air transportation energy intensity, developing and scaling up synthetic fuels, and managing aviation demand. Building upon the integrated assessment models developed at UCL’s Air Transportation Systems Laboratory, this seminar will explore the opportunities and challenges for greatly reducing the aviation sector’s climate impact.https://cassyni-user-files-prod.s3.amazonaws.com/S1tUDXvX9YZxLXdE2EmLiS https://cassyni.com/slides/outline/6dtRPgRJ8UQVjkWkT1zE9s https://cassyni.com/events/6dtRPgRJ8UQVjkWkT1zE9s/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DFkZLDAxsP1iJ6RQKAtr6J https://cassyni.com/events/6dtRPgRJ8UQVjkWkT1zE9s?videoPreview=1 The Super Neuron Model - A new generation of ANN-based Machine Learning and Applicationsnohttps://cassyni.com/events/6dtRPgRJ8UQVjkWkT1zE9s?videoPreview=12023-02-09T12:30:00+00:003626.36Journal on Image and Video ProcessingOperational Neural Networks (ONNs) are new generation network models targeting to address two major drawbacks of conventional Convolutional Neural Networks (CNNs): the homogenous network configuration and the “linear” neuron model that can only perform linear transformations over previous layer outputs. ONNs can perform any linear or non-linear transformation with a proper combination of “nodal” and “pool” operators. This is a great leap towards expanding the neuron’s learning capacity in CNNs, which thus far required the use of a single nodal operator for all synaptic connections for each neuron. This restriction has recently been lifted by introducing a superior neuron called the “generative neuron” where each nodal operator can be customized during the training in order to maximize learning. As a result, the network is able to self-organize the nodal operators of its neurons’ connections. Self-Organized ONNs (Self-ONNs) equipped with superior generative neurons can achieve diversity even with a compact configuration. We shall explore several signal processing applications of neural network models equipped with the superior neuron.https://cassyni-user-files-prod.s3.amazonaws.com/DFkZLDAxsP1iJ6RQKAtr6J https://cassyni.com/slides/outline/78Y2SN4pZvxYjX3e3TH2RB https://cassyni.com/events/78Y2SN4pZvxYjX3e3TH2RB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4ytgom5vWxjhsndVTbyCE2 https://cassyni.com/events/78Y2SN4pZvxYjX3e3TH2RB?videoPreview=1 Image storage on synthetic DNAnohttps://cassyni.com/events/78Y2SN4pZvxYjX3e3TH2RB?videoPreview=12021-03-04T12:30:00+00:003909.52Journal on Image and Video ProcessingNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/4ytgom5vWxjhsndVTbyCE2 https://cassyni.com/events/hQNvqx3jtsULeoQSYHERj/seminar/qa https://cassyni.com/slides/outline/hQNvqx3jtsULeoQSYHERj https://cassyni.com/events/hQNvqx3jtsULeoQSYHERj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JLS3HWctGfxH5JSehKt1Hg https://cassyni.com/events/hQNvqx3jtsULeoQSYHERj?videoPreview=1 Electrohydrodynamic interactions of dropletsnohttps://cassyni.com/events/hQNvqx3jtsULeoQSYHERj?videoPreview=12023-10-26T14:00:00+00:003163.84Journal of Engineering MathematicsThe interaction of fluids and electric fields is at the heart of natural phenomena such as disintegration of raindrops in thunderstorms and many applications such as ink-jet printing, microfluidics, crude oil demulsification, and electrosprays. Many of these processes involve droplets and there has been a long-standing interest in understanding drop electrohydrodynamics. While an isolated drop in applied electric fields has been extensively studied, the behavior of many drops is largely unexplored. Even the pair-wise drop interactions have received scant attention and existing models are limited to axisymmetric and two-dimensional geometries. In three dimensions, the electrohydrodynamic interactions can be quite complex and non-trivial. For example, in an applied uniform electric field, instead of chaining along the field direction, drops can initially attract in the direction of the field and move towards each other, but then separate in the transverse direction [1]. Using a combination of numerical simulations based on a boundary integral formulation and an analytical theory assuming small drop deformations, we study the dynamics of a drop pair in an applied uniform electric field at arbitrary orientation of their line-of-centers relative to the applied field direction. For identical drops covered with insoluble surfactant [2], we find that the surfactant weakens the electrohydrodynamic flow and thus dielectrophoretic interactions play more prominent role in the dynamics of surfactant-covered drops compared to clean drops. If drop conductivity is the same as the suspending fluid, a nondiffusing surfactant can arrest the drops' relative motion thereby effectively preventing coalescence. Drop dissimilarity can also have profound effect on the pair dynamics: we find that in some cases droplets can form a stable pair (tandem) that “swims” either parallel or perpendicular to the applied field direction [3]. If time permits, I will discuss particle-particle and particle-wall interactions driven by electrohydrodynamic flows due to the Onsager effect.https://cassyni-user-files-prod.s3.amazonaws.com/JLS3HWctGfxH5JSehKt1Hg https://cassyni.com/events/978Sd6evKmBJqEKsQR8xqj/seminar/qa https://cassyni.com/slides/outline/978Sd6evKmBJqEKsQR8xqj https://cassyni.com/events/978Sd6evKmBJqEKsQR8xqj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NCQDsGp5aee1dodrmWf9zN https://cassyni.com/events/978Sd6evKmBJqEKsQR8xqj?videoPreview=1 Complementary Proof Nets for Classical Logicnohttps://cassyni.com/events/978Sd6evKmBJqEKsQR8xqj?videoPreview=12023-10-04T14:00:00+00:003760.52Logica UniversalisA complementary system for a given logic is a proof system whose theorems are exactly the formulas that are not valid according to the logic in question. This article is a contribution to the complementary proof theory of classical propositional logic. In particular, we present a complementary proof-net system, CPN, that is sound and complete with respect to the set of all classically invalid (one-side) sequents. We also show that cut elimination in CPN enjoys strong normalization along with strong confluence (and, hence, uniqueness of normal forms).https://cassyni-user-files-prod.s3.amazonaws.com/NCQDsGp5aee1dodrmWf9zN https://cassyni.com/events/BaNTrWtYX3woCAoRx73bZf/seminar/qa https://cassyni.com/slides/outline/BaNTrWtYX3woCAoRx73bZf https://cassyni.com/events/BaNTrWtYX3woCAoRx73bZf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7YMu5KZuqEPZokTVADnHE6 https://cassyni.com/events/BaNTrWtYX3woCAoRx73bZf?videoPreview=1 Data-driven system analysis: Polynomial optimization meets Koopmannohttps://cassyni.com/events/BaNTrWtYX3woCAoRx73bZf?videoPreview=12023-10-19T15:00:00+00:003622.76Department of AeronauticsQuestions about stability, long-time behaviour, and the effect of uncertainty are at the heart of nonlinear system analysis. Many of these questions can be answered using "auxiliary functions", which generalize the Lyapunov functions encountered in stability analysis. Moreover, auxiliary functions can be constructed using polynomial optimization if a system is governed by known polynomial equations. But what if the governing equations are not polynomial or, worse, are not known? In this talk, I will show that auxiliary functions can be "discovered" directly from data if one combines polynomial optimization with (extended) dynamic mode decomposition. This enables one to perform data-driven system analysis without having to first identify a model for the system dynamics. The key to this is a previously unrecognized connection between auxiliary functions and the Koopman operator, which can be approximated from data with rigorous convergence guarantees. After explaining this connection, I will present examples illustrating how the method allows one to perform stability analysis, bound long-time average behaviour, and extract unstable periodic orbits for low-dimensional chaotic attractors. All results in this talk were obtained in collaboration with Jason Bramburger (Concordia University).https://cassyni-user-files-prod.s3.amazonaws.com/7YMu5KZuqEPZokTVADnHE6 https://cassyni.com/events/JVUYciTn4pdJqTVQc7YyLy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7A5Yv2gNrwWPehXQfiDM9G https://cassyni.com/slides/outline/UNSdYPQGqyhdgyVS7gKLUu https://cassyni.com/events/UNSdYPQGqyhdgyVS7gKLUu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EXWSFXSJ9DSJsscU12BtjG https://cassyni.com/events/UNSdYPQGqyhdgyVS7gKLUu?videoPreview=1 Devising surrogate models for parametric flow problems: from microfluidics to viscous turbulent flowsnohttps://cassyni.com/events/UNSdYPQGqyhdgyVS7gKLUu?videoPreview=12021-07-21T12:00:00+00:003032.76Discover Applied SciencesParametric studies in computational fluid dynamics require testing of a large number of admissible configurations. In this webinar, high-fidelity surrogate models based on the high-order hybridisable discontinuous Galerkin method and non-intrusive reduced order models based on the finite volume solver OpenFOAM will be presented, with applications spanning from geometrically parametrised problems in microfluidics to parametric flow control problems in viscous laminar and turbulent incompressible flows.https://cassyni-user-files-prod.s3.amazonaws.com/EXWSFXSJ9DSJsscU12BtjG https://cassyni.com/slides/outline/9bofnQpLAaf8ehKPCXFw1w https://cassyni.com/events/9bofnQpLAaf8ehKPCXFw1w/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XHuJPXX67m4XTeePqFzG4E https://cassyni.com/events/9bofnQpLAaf8ehKPCXFw1w?videoPreview=1 Innovative concept of vortex generator-equipped multi-drain heat recovery systems–Numerical study and energetic analysisnohttps://cassyni.com/events/9bofnQpLAaf8ehKPCXFw1w?videoPreview=12024-01-26T11:00:00+00:00703.08International Journal of ThermofluidsIn light of the environmental concerns associated with the misuse of fossil fuels and the increasing consumption of energy, heat recovery systems have become an essential option for conserving energy. In this study, an innovative design that couples a highly efficient vortex generator-based heat exchanger with a new multi-drain water application for 48 accommodations is suggested. A numerical study is done by varying the flow rate and investigating the effect on the heat transfer, overall heat transfer, and thermal enhancement factor. Besides, the economic and environmental impacts of the system are studied to investigate its sustainability. Four types of input energy are studied: coal, diesel, gas, and electricity. Results show that the design provides a temperature increase of 3.5 to 7.5 °C of cold water, consequently, the daily environmental savings are up to 0.87 € (for gas), 1.74 € (for diesel), 4.63 € (for coal), 17.63 € (for electricity US) and 2.26 € (for electricity FR). Besides, the daily economical savings are up to 7.54 $, 8.63 $, 4.63 $, and 15.07 $ respectively with a payback period of around 0.61, 1.2, 1.42, and 2.89 years for gas, diesel, coal, and electricity respectively.https://cassyni-user-files-prod.s3.amazonaws.com/XHuJPXX67m4XTeePqFzG4E https://cassyni.com/slides/outline/Mx3Q48WLYPRigrFbTSm6nh https://cassyni.com/events/Mx3Q48WLYPRigrFbTSm6nh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/K13yzY7AapqEaUeWnf5u2v https://cassyni.com/events/Mx3Q48WLYPRigrFbTSm6nh?videoPreview=1 Internal shear layers in a stratified and rotating fluidnohttps://cassyni.com/events/Mx3Q48WLYPRigrFbTSm6nh?videoPreview=12020-11-05T12:00:00+00:003999.44Leeds Institute for Fluid DynamicsIn a stratified and rotating fluid, internal shear layers are systematically generated when an object oscillates at a frequency between the buoyancy frequency and the vorticity of the fluid. In this talk, I first show that these viscous layers have a generic self-similar structure in the limit of large Reynolds numbers. Then, I consider the reflection of these layers on a boundary. I show that a strong meanflow correction is generated close to the reflection point. I provide its asymptotic structure in the limit of large Reynolds numbers according to the boundary inclination. I finally discuss applications of the results in the context of oceanography (tide) and planetary interiors (libration)https://cassyni-user-files-prod.s3.amazonaws.com/K13yzY7AapqEaUeWnf5u2v https://cassyni.com/slides/outline/5eeTXaA24H9i1WZ75ycL3f https://cassyni.com/events/5eeTXaA24H9i1WZ75ycL3f/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UpFxddbeuPDyQsVXSBtG4W https://cassyni.com/events/5eeTXaA24H9i1WZ75ycL3f?videoPreview=1 Relative equilibria and periodic orbits in a Circular Planar (2+2)-Body Problem, Equilibria in an accelerated three-body problemnohttps://cassyni.com/events/5eeTXaA24H9i1WZ75ycL3f?videoPreview=12024-02-23T14:00:00+00:003565.2Celestial Mechanics and Dynamical AstronomyAuthors: Lennard F. Bakker, Nicholas J. Freeman We present a planar four-body model, the Circular Planar (2+2)-Body Problem, for the motion of two asteroids (having small but positive masses) moving under the gravitational attraction of each other and under the gravitational attraction of two primaries (with masses much larger than the two smaller mass bodies) moving in uniform circular motion about their center of mass. The general three-body problem is investigated with the addition of an external force applied to one of the masses. It is firstly demonstrated that the centre-of-mass of the three-body system accelerates. Then, it is demonstrated that only a single, unstable, collinear equilibrium solution exits in the accelerating frame. While unstable, it is also demonstrated that this single equilibrium configuration is in principle controllable using additional control accelerations distributed between the masses. Potential applications of such an accelerated collinear equilibrium configuration are discussed for the active manoeuvring of chains of small asteroids for space resource utilisation.https://cassyni-user-files-prod.s3.amazonaws.com/UpFxddbeuPDyQsVXSBtG4W https://cassyni.com/slides/outline/D4NXDprte9TYW65a3rU4Tf https://cassyni.com/events/D4NXDprte9TYW65a3rU4Tf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NeSofbZhw27ugCL94i47LJ https://cassyni.com/events/D4NXDprte9TYW65a3rU4Tf?videoPreview=1 Superposition operators on spaces of analytic functionsnohttps://cassyni.com/events/D4NXDprte9TYW65a3rU4Tf?videoPreview=12023-05-04T15:00:00+00:003317.16Journal of Mathematical SciencesIf 𝜑 is an entire function then the superposition operator 𝑆𝜑 is defined by 𝑆𝜑(𝑓)(𝑧) = 𝜑(𝑓(𝑧)), 𝑓 ∈ Hol(𝔻), 𝑧 ∈ 𝔻. If 𝑋 and 𝑌 are two subspaces of Hol(𝔻), the question is: For which entire functions 𝜑 does the operator 𝑆𝜑 map 𝑋 into 𝑌?, and when is continuous and/or bounded? This question has been solved for a good number of pairs (𝑋, 𝑌) of spaces of analytic functions in the disc by distint authors including Cámera, Giménez, Buckley, Fernández, Bonet, Vukotic and others. After presenting some of these results, I will turn to deal with a number of contributions to the topic I have obtain in collaboration with some colleagues in the last few years.https://cassyni-user-files-prod.s3.amazonaws.com/NeSofbZhw27ugCL94i47LJ https://cassyni.com/events/VrSguhNcy5DNztmaDRjoNu/seminar/qa https://cassyni.com/slides/outline/VrSguhNcy5DNztmaDRjoNu https://cassyni.com/events/VrSguhNcy5DNztmaDRjoNu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/T13bwgxxtW21cf8WQA19kJ https://cassyni.com/events/VrSguhNcy5DNztmaDRjoNu?videoPreview=1 Hypersonic Vehicle Analyses: The Needs and Challenges of Multidisciplinary Simulationsnohttps://cassyni.com/events/VrSguhNcy5DNztmaDRjoNu?videoPreview=12024-04-16T16:00:00+00:004320.84AIAA JournalThe development of hypersonic vehicles is of broad international interest today for applications in national security, deep space exploration, and the emerging space economy. While the first hypersonic vehicle flew more than 70 years ago, their effective design still faces major technical challenges. The overarching cause of this difficulty stems from the fact that many key individual physical processes relevant to hypersonic flight are tightly coupled. The gas dynamics of the air flow around the vehicle creates temperatures of thousands of degrees leading to internal energy excitation and chemical reactions. The hot, oxidized gas in contact with the surfaces of the vehicle leads to material response phenomena such as conduction, radiation, and ablation. The thermally soaked material alters the structural response to the aerodynamic loading. Changes in the vehicle outer mold line due to ablation and structural deformation change the basic aerodynamic performance and thus affect the flight dynamics. With advanced numerical algorithms and modern computer architectures, it is becoming possible to include many of these complex processes in hypersonic vehicle analyses. This talk will review the current status for computational modeling of each separate discipline as well as efforts to couple these processes together. Key aspects for coupling include consideration of timescales associated with different processes and multi-fidelity simulation approaches.https://cassyni-user-files-prod.s3.amazonaws.com/T13bwgxxtW21cf8WQA19kJ https://cassyni.com/slides/outline/NwNEG8KGpfTbW5mzqzAsED https://cassyni.com/events/NwNEG8KGpfTbW5mzqzAsED/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NDsVHCWkynDk2htsazPr5t https://cassyni.com/events/NwNEG8KGpfTbW5mzqzAsED?videoPreview=1 Radical Chemistry in Organic Synthesisnohttps://cassyni.com/events/NwNEG8KGpfTbW5mzqzAsED?videoPreview=12022-12-07T00:00:00+00:008010.88Thieme GroupThe introduction of photoredox catalysis as a tool in organic synthesis has transformed radical chemistry from being a curiosity with low practicability into an extremely powerful area of synthetic methodology.https://cassyni-user-files-prod.s3.amazonaws.com/NDsVHCWkynDk2htsazPr5t https://cassyni.com/slides/outline/YKgi97cFAMysMqF8m7eS6q https://cassyni.com/events/YKgi97cFAMysMqF8m7eS6q/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BEB9gPXTdMGF5BKXzzysYa https://cassyni.com/events/YKgi97cFAMysMqF8m7eS6q?videoPreview=1 Adaptive moving window technique for SPH simulation of stationary shock wavesnohttps://cassyni.com/events/YKgi97cFAMysMqF8m7eS6q?videoPreview=12024-03-04T12:00:00+00:00817.0Computer Physics CommunicationsA novel adaptive moving window (AMW) technique is developed for simulating stationary shock waves in a moving coordinate system associated with a simulation box. The velocity of this system is adjusted by an iterative feedback algorithm with the purpose of establishing a desirable position of shock front. Galilean transformations are iteratively used to maintain the shape of the flow profile. The moving coordinate system has advantages in simulation over a conventional coordinate system associated with the intact material at rest. In particular, a truly steady flow regime can be established in this moving window (MW). Comparative simulation using the smoothed particle hydrodynamics method to study shock propagation in copper confirms that the AMW converges to a steady state faster than a MW technique with a fixed velocity. We demonstrate that AMW can be applied for very weak shocks. Advantage of AMW is revealed in SPH simulation of the front structure for weak shocks in porous copper that result in a partial pore compaction. Specifically, we clarify the mechanism of the partial pore collapse for shock velocities below a knee on a calculated shock Hugoniot, where this knee corresponds to the complete collapse of pores.https://cassyni-user-files-prod.s3.amazonaws.com/BEB9gPXTdMGF5BKXzzysYa https://cassyni.com/slides/outline/QuxeSruNaVgMbo4ECx2oem https://cassyni.com/events/QuxeSruNaVgMbo4ECx2oem/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AxHXL3thNjaoJNzJ4W12vA https://cassyni.com/events/QuxeSruNaVgMbo4ECx2oem?videoPreview=1 Regular p-Maps and Regular Cayley Maps of Znpnohttps://cassyni.com/events/QuxeSruNaVgMbo4ECx2oem?videoPreview=12024-02-27T02:00:00+00:003159.2The Journal of Algebraic CombinatoricsA (topological) map is a cellular decomposition of a closed surface. A common way to describe maps is to view them as 2-cell embeddings of graphs. A map is called a p-map if it has a prime p-power vertices. An orientably -regular (resp. A regular) p -map is called solvable if the group G+ of all orientation-preserving automorphisms (resp. the group G of automorphisms) is solvable; and called normal if G+ (resp. G) contains the normal Sylow p-subgroup. In this talk, it will be proved that both orientably-regular p-maps and regular p-maps are solvable and except for few cases that p ∈ {2, 3}, they are normal. Regular Cayley Maps are regular embeddings of Cayley graphs. One of a special families of regular p-maps is regular Cayley maps of elementary abelian p-groups. In this talk, a complete classification of such maps will be given and moreover, the number of these maps and their genera will be enumerated.https://cassyni-user-files-prod.s3.amazonaws.com/AxHXL3thNjaoJNzJ4W12vA https://cassyni.com/slides/outline/TPCfgH8zmnSqxjXnkdwSNh https://cassyni.com/events/TPCfgH8zmnSqxjXnkdwSNh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3t4TJcLYXLvSg7Cw1jpVSE https://cassyni.com/events/TPCfgH8zmnSqxjXnkdwSNh?videoPreview=1 Smart Searching for the Physiome Projectnohttps://cassyni.com/events/TPCfgH8zmnSqxjXnkdwSNh?videoPreview=12024-03-05T03:00:00+00:002732.6The Auckland Bioengineering InstituteThe Physiome Project's standards for biosimulation models in the Physiome Model Repository (PMR) aim to create a virtual physiological human. Despite an increase in models, users need help finding relevant ones. This thesis proposes approaches to aid search using semantic annotations and Natural Language Processing (NLP). The first approach is NLIMED, which converts free-text queries to SPARQL, while the second one is CASBERT, which encodes model entities for exploratory searches. Integrated into a web-based tool, CASBERT enables comprehensive searches, facilitating model discovery and maximizing FAIRness. These methods can be extended to other standards like SBML, promising multi-scale, multi-repository searches in the future. We further investigate CASBERT to identify unannotated entities by leveraging the hierarchical structure of the model. This exploration led to the development of a functional search tool called BMSE.https://cassyni-user-files-prod.s3.amazonaws.com/3t4TJcLYXLvSg7Cw1jpVSE https://cassyni.com/events/87v6scuXevqyC9VHqLM8gV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VjLpoUCw6YWTh1gU2EnF9Y https://cassyni.com/events/A6WX4MVdQm4jHrmXCJD573/seminar/qa https://cassyni.com/slides/outline/A6WX4MVdQm4jHrmXCJD573 https://cassyni.com/events/A6WX4MVdQm4jHrmXCJD573/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JqYCMHYPEzSLK4WHTyG3Mx https://cassyni.com/events/A6WX4MVdQm4jHrmXCJD573?videoPreview=1 Double Floquet-Bloch transforms: complex deformation of integration surfaces and far-field asymptotics of periodic structures Green's functionsnohttps://cassyni.com/events/A6WX4MVdQm4jHrmXCJD573?videoPreview=12024-04-16T13:00:00+00:003677.04MetaMATWe propose a general procedure to study double integrals arising when considering wave propagation in periodic structures. This method, based on a complex deformation of the integration surface to bypass the integrands' singularities, is particularly efficient to estimate the Green's functions of such structures in the far field. We provide several illustrative examples and explicit asymptotic formulae. Special attention is devoted to the pathological cases of degeneracies, such as Dirac conical points for instance.https://cassyni-user-files-prod.s3.amazonaws.com/JqYCMHYPEzSLK4WHTyG3Mx https://cassyni.com/events/KyxBvjCC33tQdC2XbgKckM/seminar/qa https://cassyni.com/slides/outline/KyxBvjCC33tQdC2XbgKckM https://cassyni.com/events/KyxBvjCC33tQdC2XbgKckM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FaGwJ9zhN2rQFW3iwpnWW2 https://cassyni.com/events/KyxBvjCC33tQdC2XbgKckM?videoPreview=1 Soft Acoustic Metamaterials: from 3D locally resonant metafluids to soft porous gradient index metasurfacesnohttps://cassyni.com/events/KyxBvjCC33tQdC2XbgKckM?videoPreview=12024-05-28T13:00:00+00:003596.04MetaMATSoft acoustic metamaterials are classes of functional materials for acoustics achieved by means of soft matter techniques such as microfluidics, chemical formulation or self-assembly [1]. In this talk, I will review our achievements in that field that allowed us to fabricate the first 3D acoustic metamaterial with a negative index [2]. To do that, we took benefit from the strong low-frequency Mie-type resonances of “ultra-slow” micro-beads randomly dispersed in a water-based gel. The soft porous silicone rubber material used to make these soft porous particles, not only exhibits ultra-low sound speeds (~40m/s), but also shows a strong dependence of its sound speed on the porosity [3], providing thus a material with an acoustic index varying over a wide range of values. By assembling thin stripes made of these soft porous silicone rubbers with different porosities, we have recently proposed to fabricate soft gradient-index metasurfaces, alternatively to our 3D locally resonant metafluids, for wavefront shaping. The ability of these flat and ultra-thin acoustic lenses will be demonstrated through various underwater ultrasound experiments such as beam steering, ultrasound focusing and vortex beam generation [4]. Finally, I will report on 3D underwater ultrasound focusing experiments performed with a quasi-flat high-index acoustic lens [5] whose focal length can be tuned by hardening or softening the material thanks to UV light [6].https://cassyni-user-files-prod.s3.amazonaws.com/FaGwJ9zhN2rQFW3iwpnWW2 https://cassyni.com/slides/outline/DZ3kP92JUxwNKZ55qxb2ds https://cassyni.com/events/DZ3kP92JUxwNKZ55qxb2ds/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Y1XbyMkVUWa7MDLRH8DEge https://cassyni.com/events/DZ3kP92JUxwNKZ55qxb2ds?videoPreview=1 Robust Dynamical Systems Monitoring: Learning by Modelingnohttps://cassyni.com/events/DZ3kP92JUxwNKZ55qxb2ds?videoPreview=12022-05-04T10:00:00+00:004092.92Data-Centric Engineering JournalData-Centric Engineering Webinar Series presents Professor Eleni Chatzi leading her talk on Robust Dynamical Systems Monitoring: Learning by Modeling. The DCE Webinar series is a programme of monthly virtual events about data-centric engineering: the use of data science methods and models for improving the reliability, resilience, safety, efficiency and usability of engineered systems. It is hosted by the Data-Centric Engineering journal (cambridge.org/dce) at Cambridge University Press – a peer-reviewed open access journal dedicated to the interface of data science and all engineering disciplines – with the support of The Alan Turing Institute and the Lloyd's Register Foundation.https://cassyni-user-files-prod.s3.amazonaws.com/Y1XbyMkVUWa7MDLRH8DEge https://cassyni.com/slides/outline/PSVRFWis7Fm3etL6FLhaHB https://cassyni.com/events/PSVRFWis7Fm3etL6FLhaHB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7A5a1zqnoMzfKmWUYmJMpa https://cassyni.com/events/PSVRFWis7Fm3etL6FLhaHB?videoPreview=1 Droplets skating on gas nanofilms: merging, wetting, bouncing & levitationnohttps://cassyni.com/events/PSVRFWis7Fm3etL6FLhaHB?videoPreview=12024-03-06T15:00:00+00:002978.76The Edinburgh Fluid Dynamics Group (EFDG)Recent advances in experimental techniques have enabled remarkable discoveries and insight into how the dynamics of thin gas/vapour films can profoundly influence the behaviour of liquid droplets: drops impacting solids can “skate on a film of air”, so that they can “bounce off walls”; reductions in ambient gas pressure can suppress splashing and initiate the merging of colliding droplets; and evaporating droplets can levitate on their own vapour film (the Leidenfrost effect). Despite these advances, the precise physical mechanisms governing these phenomena remains a topic of debate.   In this talk, I will overview our development of efficient computational models for the aforementioned droplet dynamics in the presence of gas nanofilms into which gas-kinetic, van der Waals and/or evaporative effects can be easily incorporated in order to address these open problems and stimulate new directions of research.  https://cassyni-user-files-prod.s3.amazonaws.com/7A5a1zqnoMzfKmWUYmJMpa https://cassyni.com/slides/outline/WMZsu5nDFfWq9hKfcnGWRs https://cassyni.com/events/WMZsu5nDFfWq9hKfcnGWRs/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QyzX41SxcQCou4f7TQyEDc https://cassyni.com/events/WMZsu5nDFfWq9hKfcnGWRs?videoPreview=1 Radiative Transfer for Atmospheres with Cloudsnohttps://cassyni.com/events/WMZsu5nDFfWq9hKfcnGWRs?videoPreview=12024-04-26T11:00:00+00:003639.04Leeds Institute for Fluid DynamicsTo study the temperature in a gas subjected to electromagnetic radiations, one may use the Radiative Transfer equations coupled with the Navier-Stokes equations. The problem has 7 dimensions; however with minimal simplifications it is equivalent to a small number of integro-differential equations in 3 dimensions. A numerical implementation using an ${\mathcal H}$-matrix compression scheme allows us to measure the effect of clouds and airplane contrails on the temperature in the atmosphere. The result is very fast and the method is capable of handling variable absorption and scattering functions of spatial positions and frequencies.https://cassyni-user-files-prod.s3.amazonaws.com/QyzX41SxcQCou4f7TQyEDc https://cassyni.com/slides/outline/RR5qSFJxs5yokbcKcJZWhj https://cassyni.com/events/RR5qSFJxs5yokbcKcJZWhj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/SBwBYb6CqM11mnSuu4GRMp https://cassyni.com/events/RR5qSFJxs5yokbcKcJZWhj?videoPreview=1 High Level Overview of AI and ML in Science and Engineeringnohttps://cassyni.com/events/RR5qSFJxs5yokbcKcJZWhj?videoPreview=12024-02-16T12:00:00+00:002846.76Brunton LabThis video describes how to incorporate physics into the machine learning process. The process of machine learning is broken down into five stages: (1) formulating a problem to model, (2) collecting and curating training data to inform the model, (3) choosing an architecture with which to represent the model, (4) designing a loss function to assess the performance of the model, and (5) selecting and implementing an optimization algorithm to train the model. At each stage, we discuss how prior physical knowledge may be embedding into the process. Physics informed machine learning is critical for many engineering applications, since many engineering systems are governed by physics and involve safety critical components. It also makes it possible to learn more from sparse and noisy data sets. SLB acknowledges support from the National Science Foundation AI Institute in Dynamic Systems and from The Boeing Company.https://cassyni-user-files-prod.s3.amazonaws.com/SBwBYb6CqM11mnSuu4GRMp https://cassyni.com/events/69oGdb5VkENvz1ZpgzyD1X/seminar/qa https://cassyni.com/slides/outline/69oGdb5VkENvz1ZpgzyD1X https://cassyni.com/events/69oGdb5VkENvz1ZpgzyD1X/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FiR4t8jZ7HTHso5CG5Kppn https://cassyni.com/events/69oGdb5VkENvz1ZpgzyD1X?videoPreview=1 A Ratio Estimator for the of Mean of a Sensitive Variable in the Presence of Lack of Trust in RRT and Measurement Errorsnohttps://cassyni.com/events/69oGdb5VkENvz1ZpgzyD1X?videoPreview=12024-05-21T14:00:00+00:003086.72Journal of Statistical Theory and PracticeRRT Models, both binary and quantitative, have been used extensively in surveys that include sensitive questions. These models allow respondents to provide randomized or scrambled responses which can later be unscrambled at an aggregate level but not at individual level. This feature protects the respondent privacy during face-to-face surveys which sometimes become necessary to decrease non-response. In this presentation we will focus on improving respondents’ trust in RRT methodology. We do so by allowing more scrambling options while maintaining the overall model quality. We will also discuss how we can take advantage of auxiliary information and account for measurement errors. https://cassyni-user-files-prod.s3.amazonaws.com/FiR4t8jZ7HTHso5CG5Kppn https://cassyni.com/events/DKEAkcFMequaurUgXGDHP/seminar/qa https://cassyni.com/slides/outline/DKEAkcFMequaurUgXGDHP https://cassyni.com/events/DKEAkcFMequaurUgXGDHP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Ks5GAH6xs681F5Ae5kxb6n https://cassyni.com/events/DKEAkcFMequaurUgXGDHP?videoPreview=1 Nektar++ Updates and Future Developmentsnohttps://cassyni.com/events/DKEAkcFMequaurUgXGDHP?videoPreview=12024-06-11T12:00:00+00:005815.08Nektar++ Development TeamThis sessions gives updates on progress, highlights new developments, reports on the merge request and provides future perspectives, and finally end with a short Q&A sessionhttps://cassyni-user-files-prod.s3.amazonaws.com/Ks5GAH6xs681F5Ae5kxb6n https://cassyni.com/slides/outline/3gZFQAqsYwcPwrL3EDAr1K https://cassyni.com/events/3gZFQAqsYwcPwrL3EDAr1K/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4QBvgtA9jyAD3JsXDAEzP8 https://cassyni.com/events/3gZFQAqsYwcPwrL3EDAr1K?videoPreview=1 Data-driven Nonlinear Aeroelastic Models of Morphing Wings For Controlnohttps://cassyni.com/events/3gZFQAqsYwcPwrL3EDAr1K?videoPreview=12020-11-20T14:00:00+00:001269.88Brunton LabIn this video, Urban Fasel describes a data-driven reduced-order aeroelastic modeling technique for morphing wings and shows its applicability for model predictive control.https://cassyni-user-files-prod.s3.amazonaws.com/4QBvgtA9jyAD3JsXDAEzP8 https://cassyni.com/events/G2mMZG1zXPTFqXZrCZja9T/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BPpthieZq8tro851xn9Kxr https://cassyni.com/slides/outline/B6HK6RYk8ovESRrWC62aRK https://cassyni.com/events/B6HK6RYk8ovESRrWC62aRK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6bTnLrhB5DFRXeQvd6UsbU https://cassyni.com/events/B6HK6RYk8ovESRrWC62aRK?videoPreview=1 A tripartite bacterial-fungal-plant symbiosis in the mycorrhiza-shaped microbiome drives plant growth and mycorrhizationnohttps://cassyni.com/events/B6HK6RYk8ovESRrWC62aRK?videoPreview=12024-06-06T18:10:00+00:00857.08New Phytologist Foundation Plant microbiomes play crucial roles in nutrient cycling and plant growth, and are shaped by a complex interplay between plants, microbes, and the environment. The role of bacteria as mediators of the 400-million-year-old partnership between the majority of land plants and, arbuscular mycorrhizal (AM) fungi is still poorly understood. Here we test whether AM hyphae-associated bacteria influence the success of the AM symbiosis. Using partitioned microcosms containing field soil, we discovered that AM hyphae and roots selectively assemble their own microbiome from the surrounding soil. In two independent experiments, we identified several bacterial genera, including *Devosia*, that are consistently enriched on AM hyphae. Subsequently, we isolated 144 pure bacterial isolates from a mycorrhiza-rich sample of extraradical hyphae and isolated *Devosia* sp. ZB163 as root and hyphal colonizer. We show that this AM-associated bacterium synergistically acts with mycorrhiza on the plant root to strongly promote plant growth, nitrogen uptake, and mycorrhization. Our results highlight that AM fungi do not function in isolation and that the plant-mycorrhiza symbiont can recruit beneficial bacteria that support the symbiosis.https://cassyni-user-files-prod.s3.amazonaws.com/6bTnLrhB5DFRXeQvd6UsbU https://cassyni.com/slides/outline/MTvdBQeeknUP7Qr3VkuujT https://cassyni.com/events/MTvdBQeeknUP7Qr3VkuujT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Wg4zMBV1UHEWnLtCrmKecE https://cassyni.com/events/MTvdBQeeknUP7Qr3VkuujT?videoPreview=1 The interplay of biotic and abiotic factors shapes tree root endophyte communities and seedling growthnohttps://cassyni.com/events/MTvdBQeeknUP7Qr3VkuujT?videoPreview=12024-06-08T14:15:00+00:00963.08New Phytologist Foundation Root endophytic microbes can alleviate plant abiotic stresses, thus potentially supporting adaptation to a changing climate during plant range shifts. While climate change is extending plant fundamental niches northward, the distribution and colonization of mutualists (e.g., arbuscular mycorrhizal fungi) and pathogens may constrain plant growth and regeneration. Yet, the degree to which biotic and abiotic factors impact plant performance and associated microbial communities at the edge of their distribution remains unclear. Here, we used root microscopy analysis, coupled with short marker sequencing, to study bacterial, fungal, and mycorrhizal root endophytic communities from sugar maple seedlings distributed across two temperate-to-boreal elevational gradients in southern Québec, Canada. Our findings demonstrate that soil pH, soil Ca, and distance to sugar maple trees are key drivers of root endophyte microbial communities, overshadowing the influence of elevation. Interestingly, changes in root fungal community composition mediated an indirect effect of soil pH on seedling growth, a pattern consistent at both sites. Overall, our findings highlight a complex role of biotic and abiotic factors in shaping tree-microbe interactions, which are in turn impacting seedling growth. These findings have important implications for tree range expansion in response to shifting climatic conditions.https://cassyni-user-files-prod.s3.amazonaws.com/Wg4zMBV1UHEWnLtCrmKecE https://cassyni.com/events/J1PPrd7ygabk5iYUr6XxCd/seminar/qa https://cassyni.com/slides/outline/J1PPrd7ygabk5iYUr6XxCd https://cassyni.com/events/J1PPrd7ygabk5iYUr6XxCd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/B3uwNq1oph6tBtknNba7xi https://cassyni.com/events/J1PPrd7ygabk5iYUr6XxCd?videoPreview=1 10th international Biometals webinarsnohttps://cassyni.com/events/J1PPrd7ygabk5iYUr6XxCd?videoPreview=12024-12-03T14:00:00+00:004434.64BioMetalsCopper will be the spotlight todayhttps://cassyni-user-files-prod.s3.amazonaws.com/B3uwNq1oph6tBtknNba7xi https://cassyni.com/events/LUdR63MbssNESf23PnSavZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FW3ufmU4u5UvJPQjVtgdHg https://cassyni.com/events/XLti75b9XwYhxvr51KgGsP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VqXYgR4Gjp9g2jNhjt6Swg https://cassyni.com/events/TtMUnJ4UTjg4wEYWMfJKLZ/seminar/qa https://cassyni.com/slides/outline/TtMUnJ4UTjg4wEYWMfJKLZ https://cassyni.com/events/TtMUnJ4UTjg4wEYWMfJKLZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BCZrUWcocaViZuZfYZqq3C https://cassyni.com/events/TtMUnJ4UTjg4wEYWMfJKLZ?videoPreview=1 My journey in desalination and water treatmentnohttps://cassyni.com/events/TtMUnJ4UTjg4wEYWMfJKLZ?videoPreview=12024-12-18T09:00:00+00:002629.04ElsevierNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/BCZrUWcocaViZuZfYZqq3C https://cassyni.com/slides/outline/7986qatS2WQooF6E5YNyT3 https://cassyni.com/events/7986qatS2WQooF6E5YNyT3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2jcbG7W4R8SNxqfovwtKU2 https://cassyni.com/events/7986qatS2WQooF6E5YNyT3?videoPreview=1 PCAN Podcast Episode 2: Dr. Cindolo and Dr. Cash on primary bladder neck obstructionnohttps://cassyni.com/events/7986qatS2WQooF6E5YNyT3?videoPreview=12024-02-20T16:00:00+00:001817.96Research Seminars by Springer NatureNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/2jcbG7W4R8SNxqfovwtKU2 https://cassyni.com/slides/outline/hzTL4mfCUKjQNqzUdPBTb https://cassyni.com/events/hzTL4mfCUKjQNqzUdPBTb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/P14bf75CnsPYaGMQXXPavi https://cassyni.com/events/hzTL4mfCUKjQNqzUdPBTb?videoPreview=1 Magnetosphere-ionosphere-thermosphere at the outer planetsnohttps://cassyni.com/events/hzTL4mfCUKjQNqzUdPBTb?videoPreview=12024-07-08T14:00:00+00:001596.16MOP2024Jupiter and Saturn host some of the most brilliant aurorae in the Solar System. Omnipresent, yet variable in intensity and planetographic extent, these emissions are just one sign of magnetosphere-ionosphere-thermosphere (MIT) coupling between giant planets and their surroundings. These rapidly rotating planets are coupled to their surrounding plasma discs through their planetary magnetic fields, which mediate the exchange of angular momentum and energy through a complex system of currents. Lorentz forces, Joule heating, and precipitating particles associated with MIT coupling modify the underlying atmosphere and affect magnetospheric flows. In the magnetosphere, angular momentum drawn from each planet accelerates plasma as it is transported away from its source location, predominately Io at Jupiter and Enceladus at Saturn. Alfvén waves and quasi-static electric fields associated with MIT coupling accelerate particles into the planetary atmospheres, generating auroral emission. Energy is also deposited into the thermosphere through Joule heating associated with corotation enforcement currents. However, questions remain as to how this energy is redistributed across the planets to produce the observed thermospheric temperatures, which exceed predictions by 100s of Kelvin. This tutorial talk reviews the current understanding of MIT coupling at the outer planets, focusing primarily on the Jovian system in light of recent advances in understanding from Juno.https://cassyni-user-files-prod.s3.amazonaws.com/P14bf75CnsPYaGMQXXPavi https://cassyni.com/events/E4CZV9wnAvAbJ45oSywubj/seminar/qa https://cassyni.com/slides/outline/E4CZV9wnAvAbJ45oSywubj https://cassyni.com/events/E4CZV9wnAvAbJ45oSywubj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/745jNFYLX4en8meUqf8f3U https://cassyni.com/events/E4CZV9wnAvAbJ45oSywubj?videoPreview=1 Plant NLR immunity activation and execution: a biochemical perspectivenohttps://cassyni.com/events/E4CZV9wnAvAbJ45oSywubj?videoPreview=12024-09-09T13:00:00+00:003164.48Royal Society PublishingPlants deploy cell-surface and intracellular receptors to detect pathogen attack and trigger innate immune responses. Inside host cells, families of nucleotide-binding/leucine-rich repeat (NLR) proteins serve as pathogen sensors or downstream mediators of immune defence outputs and cell death, which prevent disease. Established genetic underpinnings of NLR-mediated immunity revealed various strategies plants adopt to combat rapidly evolving microbial pathogens. The molecular mechanisms of NLR activation and signal transmission to components controlling immunity execution were less clear. Here, we review recent protein structural and biochemical insights to plant NLR sensor and signalling functions. When put together, the data show how different NLR families, whether sensors or signal transducers, converge on nucleotide-based second messengers and cellular calcium to confer immunity. Although pathogen-activated NLRs in plants engage plant-specific machineries to promote defence, comparisons with mammalian NLR immune receptor counterparts highlight some shared working principles for NLR immunity across kingdoms.https://cassyni-user-files-prod.s3.amazonaws.com/745jNFYLX4en8meUqf8f3U https://cassyni.com/slides/outline/GXSaiaBQNCw5ezZMzfrYKf https://cassyni.com/events/GXSaiaBQNCw5ezZMzfrYKf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EwNZkYyGhyb6uaLtJVfcU6 https://cassyni.com/events/GXSaiaBQNCw5ezZMzfrYKf?videoPreview=1 Displaying Polish group as lattice automorphism group over C_0(X) spacesnohttps://cassyni.com/events/GXSaiaBQNCw5ezZMzfrYKf?videoPreview=12021-05-13T14:00:00+00:003011.88Positivity Journal, SpringerNatureA Polish group $G$ is displayable on a Banach lattice $E$ if there exists an equivalent lattice renorming $\|| \cdot \||$ on $E$ so that $G$ is isomorphic to the lattice automorphism group on $(E, \|| \cdot \|| )$. For what cases is $G$ displayable in $E$? We examine the question for proper subgroups of lattice automorphism groups over $C_0(X)$, where $X$ is a locally compact Polish space.https://cassyni-user-files-prod.s3.amazonaws.com/EwNZkYyGhyb6uaLtJVfcU6 https://cassyni.com/slides/outline/QRsVgmZaCFeU7Wmk3DmgYV https://cassyni.com/events/QRsVgmZaCFeU7Wmk3DmgYV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Wy3cFE4LiAEVGaQoUDFhKU https://cassyni.com/events/QRsVgmZaCFeU7Wmk3DmgYV?videoPreview=1 The Leke Project: raise awareness on vaginal health in Cameroonnohttps://cassyni.com/events/QRsVgmZaCFeU7Wmk3DmgYV?videoPreview=12024-05-21T16:00:00+00:00608.0Microbiome Virtual International Forum Research on vaginal microbiome is expanding worldwide. Increasingly, research is being directed towards remote countries or communities where microbiome data were previously non-existent, and this is sometimes accompanied by challenges in communication, recruiting participants, collecting samples, and even transporting and storing these samples. The Leke project is an Isala sister project carried out in Cameroon which aims to map the vaginal microbiome of healthy women and break the taboo around vaginal health. Particularly in the Leke project, we raised awareness about vaginal health and healthy practices in remote communities by including in the conversation to men and women. In this presentation, we will explain the challenges we faced and how we overcame them to research the vaginal microbiome. Link to Josiane’s blog about the project: <https://isala.be/en/the-leke-project-a-journey-to-the-isala-sister-project-in-cameroon/>.https://cassyni-user-files-prod.s3.amazonaws.com/Wy3cFE4LiAEVGaQoUDFhKU https://cassyni.com/events/97iX2KUXnLdZtxNTSWEusb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6Lucr7W4s9pA3MDASGCJpE https://cassyni.com/events/PwCGXTQAMSAeJ3nEF7eiNH/seminar/qa https://cassyni.com/slides/outline/PwCGXTQAMSAeJ3nEF7eiNH https://cassyni.com/events/PwCGXTQAMSAeJ3nEF7eiNH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/J2FREmwVTDGpFJLCgC1SHk https://cassyni.com/events/PwCGXTQAMSAeJ3nEF7eiNH?videoPreview=1 Diagnosing and coding Chronic kidney diseasenohttps://cassyni.com/events/PwCGXTQAMSAeJ3nEF7eiNH?videoPreview=12024-10-08T10:00:00+00:00925.52North West London Kidney Carenull Image credit: [TopSphere Media (Unsplash)](https://unsplash.com/photos/woman-in-black-crew-neck-shirt-wearing-blue-earbuds-WxRd7byFxs4). Image credit: [Markus Spiske (Unsplash)](https://unsplash.com/photos/colorful-software-or-web-code-on-a-computer-monitor-Skf7HxARcoc). Image credit: [TopSphere Media (Unsplash)](https://unsplash.com/photos/woman-in-black-crew-neck-shirt-wearing-blue-earbuds-WxRd7byFxs4). Image credit: [Rana Sawalha (Unsplash)](https://unsplash.com/photos/man-standing-on-beach-during-daytime-IhuHLIxS_Tk).https://cassyni-user-files-prod.s3.amazonaws.com/J2FREmwVTDGpFJLCgC1SHk https://cassyni.com/events/VNKv2yWwBUG3RTN2FjtcKf/seminar/qa https://cassyni.com/slides/outline/VNKv2yWwBUG3RTN2FjtcKf https://cassyni.com/events/VNKv2yWwBUG3RTN2FjtcKf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NrLLN12VmmsasaArn8g3ug https://cassyni.com/events/VNKv2yWwBUG3RTN2FjtcKf?videoPreview=1 EDL Technology Development at NASA, and Overview of Titan Aerothermal Environments and EDL sensors for Dragonfly.nohttps://cassyni.com/events/VNKv2yWwBUG3RTN2FjtcKf?videoPreview=12024-09-16T10:00:00+00:003325.04Department of AeronauticsThis presentation will provide an overview of 3 separate topics: 1) EDL Technology Development at NASA as part of the Entry Systems Modeling (ESM) project, including dynamic stability, TPS materials model development, aeroshell heating and guidance, navigation and control. 2) The aerothermal environments experienced during Dragonfly's entry at Titan 3) The EDL sensors to measure the Dragonfly aeroshell performance at Titan, known as DrEAM (Dragonfly Entry Aerosciences Measurements)https://cassyni-user-files-prod.s3.amazonaws.com/NrLLN12VmmsasaArn8g3ug https://cassyni.com/events/5fEXvnydWrby5Ebh84iH5X/seminar/qa https://cassyni.com/slides/outline/5fEXvnydWrby5Ebh84iH5X https://cassyni.com/events/5fEXvnydWrby5Ebh84iH5X/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4KNLMRJz4wACQtx48FZkqt https://cassyni.com/events/5fEXvnydWrby5Ebh84iH5X?videoPreview=1 Health of Autistic Women: State of the Field and Future Directionsnohttps://cassyni.com/events/5fEXvnydWrby5Ebh84iH5X?videoPreview=12024-10-09T12:00:00+00:003596.4Women's HealthAt least 1% of the world’s population is autistic, meaning that they experience and process the world around them in ways which are different to the non-autistic majority. Historically, the focus of research and the image of autism has very much been male. Changes to the diagnostic conceptualisation of autism in the last 20 years, however, has led to an increase in the diagnosis of autism in women and girls, and the recognition that they may have different life experiences and support needs than autistic men. Having been ignored, overlooked, and at times actively silenced, much less is known about autistic women than their male counterparts. The study of autistic women is still in its infancy, but suggests that there are a wide range of differences which are only just beginning to be understood in terms of how autism interacts with gender - including those who are transgender, non-binary, or have other gender identities. This special collection from Women’s Health will explore what is known about the physical, mental, social, and emotional wellbeing of autistic women, encompassing original research, reviews, and perspectives from autistic women.https://cassyni-user-files-prod.s3.amazonaws.com/4KNLMRJz4wACQtx48FZkqt https://cassyni.com/events/RungiBzG7GPQPm4Tc5Wenq/seminar/qa https://cassyni.com/slides/outline/RungiBzG7GPQPm4Tc5Wenq https://cassyni.com/events/RungiBzG7GPQPm4Tc5Wenq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HN22wVeWdFy28mLfQ6VYF8 https://cassyni.com/events/RungiBzG7GPQPm4Tc5Wenq?videoPreview=1 Advancing the Reactivity of the Isocyanide Functionalitynohttps://cassyni.com/events/RungiBzG7GPQPm4Tc5Wenq?videoPreview=12024-10-17T12:00:00+00:003518.84Tetrahedron Chem and Tetrahedron Green ChemIsocyanides are powerful building blocks whose unique reactivity has been harnessed in an extraordinary array of multi-component reactions, insertions, radical additions, and cationic cascades. The extraordinary reactivity emanates from the highly unusual electronic structure of the divalent isocyanide carbon that has both nucleophilic and electrophilic character that serves to initiate most reactions of isocyanides. In contrast, there is a serious dearth of reactions available for manipulating the carbon scaffold of isocyanides that limits the synthetic potential of isocyanoalkanes and isocyanoalkenes. We have developed several different methods to manipulate the carbon scaffold of isocyanides ranging from the use of Asmic to address the long-standing difficulty of simple alkylations to the first conjugate additions to unactivated isocyanoalkenes. The synthesis and reactivity of isocyanides is surveyed with a focus on accessing complex nitrogenous scaffolds.https://cassyni-user-files-prod.s3.amazonaws.com/HN22wVeWdFy28mLfQ6VYF8 https://cassyni.com/slides/outline/UP2hwcDtJZ9tkhY29mRHWm https://cassyni.com/events/UP2hwcDtJZ9tkhY29mRHWm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/M5zdshQmnVtiJL9d11dVgz https://cassyni.com/events/UP2hwcDtJZ9tkhY29mRHWm?videoPreview=1 Permanent hitchhikers: how human gut microbes diversified with and adapted to their hostsnohttps://cassyni.com/events/UP2hwcDtJZ9tkhY29mRHWm?videoPreview=12021-09-14T10:00:00+00:002045.32Microbiome Virtual International Forum Coevolution of humans with gut bacteria requires a shared evolutionary history. Host-microbial cophylogeny has been shown for hominids, but within humans, only the stomach bacterium *Helicobacter pylori* is known to have codiversified with its host. Human populations are known to harbor distinct strains of bacterial species and this is generally attributed to differences in environment and diet, however, codiversification through long-term associations could also contribute to these patterns. To test for cophylogeny between gut microbiota and their human hosts, we analyzed paired human genotypes and bacterial strain genotypes from fecal metagenomes obtained from five countries. Our results indicate that strains of common gut bacteria have transmitted vertically for thousands of generations. In accord, strains displaying patterns of cophylogeny are also shared between mothers and infants. Patterns of strain transfer between populations are consistent with an African origin for taxa showing cophylogeny. Our results indicate long-term fidelity of gut microbial strains with human populations, creating opportunities for coevolution.https://cassyni-user-files-prod.s3.amazonaws.com/M5zdshQmnVtiJL9d11dVgz https://cassyni.com/slides/outline/5AZJmUpDg389FmcBKxbJuK https://cassyni.com/events/5AZJmUpDg389FmcBKxbJuK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HP8c2a4LVZjykvSHBUmYc6 https://cassyni.com/events/5AZJmUpDg389FmcBKxbJuK?videoPreview=1 A Microbiome Restoration Strategy Modulates the Gut Microbiome and Metabolic Markers in Healthy Adultsnohttps://cassyni.com/events/5AZJmUpDg389FmcBKxbJuK?videoPreview=12021-11-09T12:00:00+00:0059.56Microbiome Virtual International Forum The dramatic increase of chronic diseases in industrialized societies might be driven in part by a disruption of gut microbiome composition and function (e.g., reduced fiber fermentation) and impaired intestinal barrier integrity. We developed a microbiome restoration strategy based on a diet that resembles key aspects of a non-industrialized diet (Non-Ind) and a probiotic Limosilactobacillus reuteri (a species rarely found in microbiome from industrialized populations). Using a randomized controlled pilot study, 30 participants consumed either the Non-Ind diet or their usual diet in a crossover fashion for three weeks each. Participants were also divided into three groups and consumed either a single dose of one of two Lm. reuteri strains or a placebo on day four of each diet period. The Non-Ind diet enhanced the temporal persistence of one of the Lm. reuteri strains, but had no measurable effects on microbiome and host. In contrast, the Non-Ind diet shifted overall fecal microbiome composition (R2=0.015, p=0.001; ADONIS), and significantly altered 56% of Amplicon Sequence Variants obtained from 16S dataset (FDR lower than 0.05), 22% of species-level genome bins, and 21% of metabolic pathways obtained from metagenomic dataset (FDR lower than 0.05). Bacteria fermentation was enhanced, exhibited by increased concentration of total fecal short-chain fatty acids (+10.7%, p=0.03) and reduced fecal pH (-3.8%, p=0.002). Furthermore, we observed reductions in six chronic disease risk markers (all p lower than 0.01): total cholesterol (-14.1%), low-density lipoprotein cholesterol (-16.8%), high-density lipoprotein (HDL) cholesterol (-11.3%), non-HDL cholesterol (-15.2%), glucose (-6.3%), and C-reactive protein (-14.2%). The diet also reduced fecal calprotectin (-21.0%, p=0.002) and zonulin levels (-14.9%, p=0.025) that are markers of gut inflammation and impaired barrier functions, respectively. Our study demonstrates pronounced beneficial effects of a microbiome restoration strategy based on the Non-Ind diet on metabolic markers of health. The findings provide valuable information for improving human health in modern societies. Ongoing analyses are exploring the mechanistic links between diet-induced changes in the gut microbiome and the physiological effects on the host.https://cassyni-user-files-prod.s3.amazonaws.com/HP8c2a4LVZjykvSHBUmYc6 https://cassyni.com/slides/outline/7doKzu3qsKtdci5jseVwdF https://cassyni.com/events/7doKzu3qsKtdci5jseVwdF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EJDh4SqjmFvR8VfeNRNBvE https://cassyni.com/events/7doKzu3qsKtdci5jseVwdF?videoPreview=1 Strong oral plaque microbiome signatures for dental implant diseases identified by strain-resolution metagenomicsnohttps://cassyni.com/events/7doKzu3qsKtdci5jseVwdF?videoPreview=12022-01-11T13:00:00+00:0062.68Microbiome Virtual International Forum Dental implants are installed in an increasing number of patients. Mucositis and peri-implantitis are common microbial-biofilm-associated diseases affecting the tissues that surround the dental implant and are a major medical and socioeconomic burden. By metagenomic sequencing of the plaque microbiome in different peri-implant health and disease conditions (113 samples from 72 individuals), we found microbial signatures for peri-implantitis and mucositis and defined the peri-implantitis-related complex (PiRC) composed by the 7 most discriminative bacteria. The peri-implantitis microbiome is site specific as contralateral healthy sites resembled more the microbiome of healthy implants, while mucositis was specifically enriched for Fusobacterium nucleatum acting as a keystone colonizer. Microbiome-based machine learning showed high diagnostic and prognostic power for peri-implant diseases and strain-level profiling identified a previously uncharacterized subspecies of F. nucleatum to be particularly associated with disease. Altogether, we associated the plaque microbiome with peri-implant diseases and identified microbial signatures of disease severity. Link to the OA paper: https://www.nature.com/articles/s41522-020-00155-7https://cassyni-user-files-prod.s3.amazonaws.com/EJDh4SqjmFvR8VfeNRNBvE https://cassyni.com/slides/outline/4BG6g7XAo81zb1nBDz7z6R https://cassyni.com/events/4BG6g7XAo81zb1nBDz7z6R/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AbMfDKVJUKmgb5xJYtWEqL https://cassyni.com/events/4BG6g7XAo81zb1nBDz7z6R?videoPreview=1 Therapies for the Tract: How to Improve Our Intestinal Microbiomenohttps://cassyni.com/events/4BG6g7XAo81zb1nBDz7z6R?videoPreview=12022-03-08T12:00:00+00:002460.56Microbiome Virtual International Forum No abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/AbMfDKVJUKmgb5xJYtWEqL https://cassyni.com/slides/outline/EYsneU7C1jeR7X5KF64smw https://cassyni.com/events/EYsneU7C1jeR7X5KF64smw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RQnAVCPAEhSqvwx5tPU2xE https://cassyni.com/events/EYsneU7C1jeR7X5KF64smw?videoPreview=1 The infant gut commensal Bacteroides dorei presents a generalized transcriptional response to various Human Milk Oligosaccharidesnohttps://cassyni.com/events/EYsneU7C1jeR7X5KF64smw?videoPreview=12022-06-15T14:00:00+00:00646.04Microbiome Virtual International Forum Human milk oligosaccharides (HMOs) are a family of glycans found in breastmilk with over 200 identified structures. Despite being the third-largest solid component in breastmilk, HMOs are indigestible by infants, and they serve as food for the infant gut bacteria. Most research thus far has focused on Bifidobacterium species that harbor many glycoside hydrolases (GHs) tailored to break the carbon bonds in HMO molecules. However, there are additional microbes in the infant gut, such as Bacteroides species, with increasing evidence that they, too, are able to break-down HMOs. To study the unbiased impact of breastfeeding on the infant gut microbiome, we need to investigate the underlying mechanisms of HMO utilization by all members of the infant gut. Here, we developed an optimized system for isolating Bacteroides strains from infant stool samples. We then examined the HMO utilization capacity of multiple Bacteroides isolates by performing growth curves on six common HMOs (2’-FL, DFL, 3’-SL, 6’-SL, LNT, LNnT). Isolates often displayed similar growth characteristics on similarly-structured HMOs, like sialylated or fucosylated sugars. We identified variation in HMO utilization across multiple strains of the same species, and chose to focus here on a Bacteroides dorei isolate that was able to utilize the test HMOs. We performed RNA sequencing on B. dorei cultures, comparing the transcriptional profile in minimal media supplemented with glucose or HMOs. We showed that B. dorei employs an extensive metabolic response to HMOs. Surprisingly, there was no clear up-regulation for most GH families previously known to break-down HMOs, possibly because they were almost exclusively described in Bifidobacterium species. Instead, B. dorei exhibits a generalized response to HMOs, markedly up-regulating several shared GH families across all conditions. Within each GH family, B. dorei displays a consistent pattern of up-regulation of some genes with down-regulation of the others. This response pattern to HMOs has yet to be described in other commensals of the infant gut. Our work highlights the importance of expanding the HMO-microbiome studies beyond Bifidobacterium species, sheds light on the differences across Bacteroides strains in terms of HMO utilization, and paves the way to understanding the mechanisms enabling Bacteroides HMO utilization.https://cassyni-user-files-prod.s3.amazonaws.com/RQnAVCPAEhSqvwx5tPU2xE https://cassyni.com/slides/outline/F3XPh9kiTCCU7HcCqXMg3F https://cassyni.com/events/F3XPh9kiTCCU7HcCqXMg3F/abstract https://cassyni-user-files-prod.s3.amazonaws.com/T93n9b9VmoPBnQUyfmbsrn https://cassyni.com/events/F3XPh9kiTCCU7HcCqXMg3F?videoPreview=1 Exploring the human lung virome from shotgun metagenomic studiesnohttps://cassyni.com/events/F3XPh9kiTCCU7HcCqXMg3F?videoPreview=12022-10-18T14:00:00+00:00648.04Microbiome Virtual International Forum Introduction: The lung virome is an understudied portion of the human microbiome that is gaining increasing attention in medical research due to its public health significance. It is estimated that up to 95% of the lung virome remains uncharacterised. Here, we aim to catalogue the virome associated with the human respiratory tract by reanalysing publicly available data using a newly-developed pipEline for Viral assEmbly and chaRactEriSaTion (EVEREST). Methods: Lung virome studies (n=85) utilising shotgun metagenomics and lung-attributed samples were gathered from public databases. Following manual curation (n=44), bioproject data was inputted into EVEREST (https://agudeloromero.github.io/EVEREST/), resulting in viral discovery and taxonomic classification of known and unknown viruses. Complete and high-quality contigs were further assessed for genomic characterisation. Results: From a singular bioproject (PRJEB32062), 182 viral contigs were captured and 14 were classified as complete/high-quality. Those contigs lengths ranged between 12-387 kilobases. Focusing on three of the complete/high-quality contigs, we discovered two novel prophages (Caudovirales), and a new bacteriophage (Siphoviridae). Additionally, putative protein coding sequence regions were scanned, which ranged between 50-67 proteins. Annotation analysis showed phage-associated proteins, including proteases, DNA binding proteins and tail sheath and tube proteins, among others. Conclusion: We identified known and novel viruses utilising publicly available lung metagenome studies. Knowledge gained in the pulmonary virome will facilitate additional understanding of the virus-host microbiome interaction. We are in the process of expanding the EVEREST pipeline to other uncharacterised human niches. Grant Support: Pawsey Supercomputing Research Centre, and Australian Government Research Training Program Scholarship.https://cassyni-user-files-prod.s3.amazonaws.com/T93n9b9VmoPBnQUyfmbsrn https://cassyni.com/slides/outline/9cPkBddwdA7PiRMyEcMt3o https://cassyni.com/events/9cPkBddwdA7PiRMyEcMt3o/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NpNjzcEew3Xxk13xtW8SMC https://cassyni.com/events/9cPkBddwdA7PiRMyEcMt3o?videoPreview=1 Dynamic changes in small intestinal stoma microbiotanohttps://cassyni.com/events/9cPkBddwdA7PiRMyEcMt3o?videoPreview=12022-12-14T15:00:00+00:00619.76Microbiome Virtual International Forum Ileum has a distinct microbiota but human studies investigating its composition and function have been limited by the inaccessibility of the ileum without purging and/or deep intubation. In this recently published study, we investigated inherent instability, temporal dynamics, and the contribution of fed to the otherwise inaccessible small and large intestines. Longitudinal samples from the ileum before and after stoma formation indicated that ileostoma microbiotas represented that of the intact small intestine. Ileal and colonic stoma microbiotas were confirmed as distinct, and two types of instability: i) inter-digestive purging followed by the rapid postprandial blooming of bacterial biomass and sub-strain appearance and ii) disappearance within individual taxa after feeding. In contrast to the relative stability of colonic microbiota, small intestinal microbiota biomass and its sub-strain composition can be highly dynamic. Link to OA paper: https://www.sciencedirect.com/science/article/pii/S1931312822005157?dgcid=coauthorhttps://cassyni-user-files-prod.s3.amazonaws.com/NpNjzcEew3Xxk13xtW8SMC https://cassyni.com/slides/outline/KVPTDw6Kog7SiR4Q2k4gpM https://cassyni.com/events/KVPTDw6Kog7SiR4Q2k4gpM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GtbVSQUMfYtng9Wcn3x7pA https://cassyni.com/events/KVPTDw6Kog7SiR4Q2k4gpM?videoPreview=1 Discovery and Characterisation of Temperate Gut Bacteriophagesnohttps://cassyni.com/events/KVPTDw6Kog7SiR4Q2k4gpM?videoPreview=12023-02-15T11:00:00+00:00640.04Microbiome Virtual International Forum Bacteriophages are ubiquitous across all environments and influence their bacterial hosts in diverse ways. Within the human gut the bacterial concentration is estimated to be around 1011 cells per gram of faeces, yet the phage concentration is significantly lower at around 109 phages per gram of faeces. However, these raw counts fail to capture the prophages, which are integrated phages residing withing a bacterial host chromosome. Prophages can constitute up to 20% of the host bacterial genome, greatly impacting their host’s function, evolution, and diversification. Here we characterised a large collection of bacterial isolates originating from the human gut and identify their prophage elements. Using a broad panel of induction conditions under anaerobic conditions we identify and begin to experimentally characterise these novel and actively replicating temperate phages of the human gut.https://cassyni-user-files-prod.s3.amazonaws.com/GtbVSQUMfYtng9Wcn3x7pA https://cassyni.com/slides/outline/XqbZP2GSn7xJc6JD16dQxV https://cassyni.com/events/XqbZP2GSn7xJc6JD16dQxV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EAipRikDpZffwcEWvhym2N https://cassyni.com/events/XqbZP2GSn7xJc6JD16dQxV?videoPreview=1 The effect of domestic water quality on the development of the infant gut microbiomenohttps://cassyni.com/events/XqbZP2GSn7xJc6JD16dQxV?videoPreview=12023-06-21T11:00:00+00:00572.04Microbiome Virtual International Forum The infant gut microbiome begins development at birth, with major transition points occurring around the commencement of breastfeeding, the introduction of solid foods, and the cessation of breastfeeding. Until around three years of age, the development of the infant gut microbiome remains highly plastic and easily influenced by environmental factors. Developing a diverse and rich gut microbiome during this sensitive period is crucial to setting up a stable gut microbiome into adulthood, and to prevent gut dysbiosis. We have characterised the overall composition and functional profiles of the 6-month old gut microbiome using whole genome shotgun metagenomics sequencing and identified the key influencing environmental factors. Specifically, we discuss the effect of timing of solid food introduction, and feeding method on diversity. We also identified the differences in colonising species between breastfed and bottle-fed infants. We found the 6-month gut microbiome to be characterised by high rates of inter-individual variation. We also found infants fed exclusively formula milk had a higher overall diversity than infants fed a breastmilk diet and breastfed infants had a higher abundance of Bifidobacterium spp. We also did not identify any significantly different metabolic pathways between different environmental factors.https://cassyni-user-files-prod.s3.amazonaws.com/EAipRikDpZffwcEWvhym2N https://cassyni.com/slides/outline/Su7WvBoCPYRHCzarzcvREM https://cassyni.com/events/Su7WvBoCPYRHCzarzcvREM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6ERTEu7T9FiPA6v6eqvZcA https://cassyni.com/events/Su7WvBoCPYRHCzarzcvREM?videoPreview=1 UKRN: A Space Odyssey (a journey through the STAR and METEOR projects)nohttps://cassyni.com/events/Su7WvBoCPYRHCzarzcvREM?videoPreview=12024-07-02T08:00:00+00:006338.92UKRNThe quality and rigour of research is affected by the conditions in which it takes place. For example, a culture in which constructive challenge and learning are valued is likely to lead to better research than one where they are not. An environment that includes sustained and effective support for transparent research practices such as open data is likely to lead to higher uptake of those practices. Two UKRN projects, co-funded by UKRN’s members, are investigating these issues. They are [STAR](https://www.ukrn.org/activities/star/) (Sustainable and TrAnsparent Research data), reviewing the arrangements institutions have in place to support open data, and [METEOR](https://www.ukrn.org/activities/enhancing-research-culture/) (METa-research for the Enhancement of Research culture), exploring how institutions use research evidence to inform their research culture. This webinar will talk through the preliminary findings and emerging themes from each project and aims to stimulate discussion around these themes with the UKRN community during the Q&A.https://cassyni-user-files-prod.s3.amazonaws.com/6ERTEu7T9FiPA6v6eqvZcA https://cassyni.com/slides/outline/TPUtpaHroPi7RCuxeUiXTj https://cassyni.com/events/TPUtpaHroPi7RCuxeUiXTj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/E6KjjR64djwzYiC2Ztqs66 https://cassyni.com/events/TPUtpaHroPi7RCuxeUiXTj?videoPreview=1 Shock Response Spectrum of Linear Viscous and Nonlinear Discontinuous Coulomb Dampingnohttps://cassyni.com/events/TPUtpaHroPi7RCuxeUiXTj?videoPreview=12025-06-24T11:00:00+00:00482.32NODYSThis study investigates a combined viscous and Coulomb-damped harmonic oscillator, both numerically and experimentally, using a custom-built tribo-oscillatory test rig. The shock response spectrum (SRS) shows that tuning viscous and Coulomb damping can control the reduction of the first peak response and its range. As Coulomb damping increases, the dispersion range of the system's response peaks in the SRS increases, while viscous damping causes this range to decrease.https://cassyni-user-files-prod.s3.amazonaws.com/E6KjjR64djwzYiC2Ztqs66 https://cassyni.com/slides/outline/YKxwHQm7ByF8pJdJexRXBs https://cassyni.com/events/YKxwHQm7ByF8pJdJexRXBs/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GC5ZBKb3VwJQeuhFjRs6uL https://cassyni.com/events/YKxwHQm7ByF8pJdJexRXBs?videoPreview=1 Extension of Phase-Locked Loop Experiment for Application to Ground Vibration Testnohttps://cassyni.com/events/YKxwHQm7ByF8pJdJexRXBs?videoPreview=12025-06-24T10:00:00+00:00635.2NODYSPhase-locked-loop (PLL) experiments have been successfully used in the recent years to obtain backbone and frequency response curves of nonlinear structures. However, applications to large-scale structures as for instance in a ground vibration test (GVT) have been scarcely addressed, mainly because of difficulties in the tuning of the controller and limitations to single-input single-output (SISO) control. To overcome these challenges, we propose a variation of the PLL that requires only one control parameter, thus importantly reducing the tuning effort. A method to systematically determine this parameter is presented, making the proposed design less heuristic. Extension to multi-input multi-output (MIMO) control is also highlighted, which expands its potential to identify complex structures such as aircrafts. Numerical and experimental studies validate the new design.https://cassyni-user-files-prod.s3.amazonaws.com/GC5ZBKb3VwJQeuhFjRs6uL https://cassyni.com/slides/outline/QvEsbA4Ec6wd4GSQ6notjo https://cassyni.com/events/QvEsbA4Ec6wd4GSQ6notjo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EDV8zazwk761xxWohH8ziz https://cassyni.com/events/QvEsbA4Ec6wd4GSQ6notjo?videoPreview=1 Towards a High-Performance Software Implementation of Symbolic Computational Dynamicsnohttps://cassyni.com/events/QvEsbA4Ec6wd4GSQ6notjo?videoPreview=12025-06-24T10:00:00+00:00788.36NODYSThe use of symbolic computation is now well integrated within academic research and teaching, world-wide, however it is not yet as prevalent in industry. This paper explores the requirements for a practical tool for the modelling and solution of application problems that may be defined mathematically as time variant, and therefore definable either by ordinary differential equations or by partial differential equations and boundary conditions.https://cassyni-user-files-prod.s3.amazonaws.com/EDV8zazwk761xxWohH8ziz https://cassyni.com/slides/outline/88CL1v4PgY7EecsTjB8DmX https://cassyni.com/events/88CL1v4PgY7EecsTjB8DmX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9eVJKGGLgcy4pbmo4xKPuY https://cassyni.com/events/88CL1v4PgY7EecsTjB8DmX?videoPreview=1 Nonlinear Propagation of Solitary Wave in a Tubular Origami Designed Metamaterial: An Idealized Elastic Modelnohttps://cassyni.com/events/88CL1v4PgY7EecsTjB8DmX?videoPreview=12025-06-24T11:00:00+00:001109.36NODYSKresling origami is one of the patterns based on a non-rigid, elastically foldable structure composed of a network of creases. The primary emphasis in this field is on the kinematic analysis of deployment to enhance compactness and explore unique static mechanical properties, such as auxeticity. The main focus is to analyze the actuation mechanism in the static domain, stability, and bifurcations using the Kresling pattern by varying geometric parameters. In this study, we have designed and analyzed a unique tubular material-based multiunit Kresling model, demonstrating the magnetic-driven actuation and segment-wise wave propagation of structures while simultaneously analyzing their static actuation characteristics. We have designed triangulated tubular origami-based metamaterials that enable the strain-softening/hardening characteristics via elastically deformable material-inspired design. To investigate the mechanical properties of triangulated non-rigid Kresling origami-inspired metamaterials with the actuation ability of hard-magnetic active materials, we have used finite element simulation for modeling the Kresling structures and determining the actuation characteristics under axial and rotational conditions. We develop a mathematical model for triangulated 2DOF spring-based Kresling origami. We investigate the magnetic-based deformable Kresling model and solitary wave dynamics in the triangulated Kresling origami metamaterials system. The numerical findings suggest that the Kresling origami structures have excellent potential for creating complex and deployable systems in various engineering applications, including vibration absorption, soft robotics, and medical devices.https://cassyni-user-files-prod.s3.amazonaws.com/9eVJKGGLgcy4pbmo4xKPuY https://cassyni.com/slides/outline/G2bcsUvg7DttxfPSVA6vMj https://cassyni.com/events/G2bcsUvg7DttxfPSVA6vMj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/YLmePkd13fcRsbFLZ1KJCn https://cassyni.com/events/G2bcsUvg7DttxfPSVA6vMj?videoPreview=1 The role of zonal structures as mediators of energetic particles and turbulencenohttps://cassyni.com/events/G2bcsUvg7DttxfPSVA6vMj?videoPreview=12025-01-09T16:00:00+00:002306.88Journal of Plasma PhysicsSpatial gradients of density and temperature are present in tokamak plasmas. Microinstabilities grow due to these gradients, and nonlinearly interact, forming turbulence. Zonal (i.e. axisymmetric) structures (ZS) take an important role in the nonlinear saturation of turbulence. Energetic particle populations are also present in tokamak plasmas due to fusion reactions, and in part due to external heating mechanisms. In the recent years, the interaction of EPs and turbulence has taken a particular attention of the magnetic-confinement fusion community. A global gyrokinetic model is necessary, if one wants to address such an intrinsically multiscale kinetic problem. In this work, we investigate the nonlinear dynamics of ZS as mediators of turbulence and EPs. The main theoretical tool is the global particle-in-cell code ORB5, originally developed for electrostatic turbulence studies, and later on extended to its multispecies electromagnetic version. The effect of the EPs on the ZS will be shown, and the role of macroscopic instabilities as mediators will be considered.https://cassyni-user-files-prod.s3.amazonaws.com/YLmePkd13fcRsbFLZ1KJCn https://cassyni.com/slides/outline/AbTyMxouHBopZo9CtF78NH https://cassyni.com/events/AbTyMxouHBopZo9CtF78NH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TQHbvv9kf65QUVXzYXcJUe https://cassyni.com/events/AbTyMxouHBopZo9CtF78NH?videoPreview=1 Observations of magnetised, collisionless shocks in laser-driven experimentsnohttps://cassyni.com/events/AbTyMxouHBopZo9CtF78NH?videoPreview=12024-07-11T15:00:00+00:003073.0Journal of Plasma PhysicsMagnetized, collisionless shocks are observed throughout the universe, including within supernova remnants and at the Earth’s magnetopause. These shocks have the potential to accelerate particles to far greater energies than other astrophysical processes and may provide a source of high-energy cosmic rays. One challenge, yet to be addressed, is determining the exact mechanism of the acceleration, and resulting energy dissipation by these shock waves. Designing a laboratory-based experiment that can create and investigate these shocks is advantageous for testing different theories and developing our knowledge of this phenomena. I will present results from an experiment performed at the Omega laser facility where we use gas jet and MIFED assembly provide a pre-ionized, pre-magnetized background plasma, through which a shock wave is launched. We diagnose the effect of the background magnetic fields on the shock formation using both temporally and spatially resolved Thomson scattering. This allow us to measure the plasma conditions, as well as identify where the background and piston material are spatially located. We are also able to measure the evolving electromagnetic field structures using proton probing. The results assist in benchmarking particle-in-cell codes and hydrodynamic models as well as interpreting measurements from spacecrafts, to gain a better understanding of the underlying physics.https://cassyni-user-files-prod.s3.amazonaws.com/TQHbvv9kf65QUVXzYXcJUe https://cassyni.com/events/B67aQeTRieMsZZg6UgPvdb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/My9xRQ2yq3z1M5xCXuNQXG https://cassyni.com/slides/outline/MTktVdZLLcv2EYfdnMHFwj https://cassyni.com/events/MTktVdZLLcv2EYfdnMHFwj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Jfm3CK8K6YiNZSSSDxynDc https://cassyni.com/events/MTktVdZLLcv2EYfdnMHFwj?videoPreview=1 Towards a unified picture of energy partition in unmagnetized collisionless shock wavesnohttps://cassyni.com/events/MTktVdZLLcv2EYfdnMHFwj?videoPreview=12023-09-14T15:00:00+00:002774.68Journal of Plasma PhysicsCollisionless shock waves shape the nonthermal emission in a wide range of environments, including modern laboratory experiments and astrophysical outflows. In weakly magnetized plasma flows, self-generated nonlinear electromagnetic plasma processes are inferred to heat and accelerate electrons and ions. Understanding the mechanisms that underpin the energy transfer between plasma species and the downstream temperature ratio between electrons and ions constitutes a fundamental challenge in modeling such blast waves. In this talk, I will outline recent theoretical efforts to model the transport of electrons in Weibel-mediated shocks. I will introduce a new model accounting for electron heating in an ambipolar-type process through the interplay between pitch-angle scattering in the microturbulence and the coherent electrostatic field induced by the difference in inertia between species. Via analytical kinetic and fluid estimates, a semi-analytical Monte Carlo-Poisson method, and large-scale ab-initio Particle-In-Cell simulations, I will discuss the electron-ion energy partition in the downstream of high Alfvén Mach numbers shocks relevant to supernova remnants and laboratory experiments. I will then present the extension of this model to the relativistic regime to demonstrate equipartition inferred from the afterglow emission of gamma-ray bursts. Finally, I will explore the implications of this model on electron injection in nonthermal distributions.https://cassyni-user-files-prod.s3.amazonaws.com/Jfm3CK8K6YiNZSSSDxynDc https://cassyni.com/slides/outline/J1DfAr2fGR3PCrN58guJQu https://cassyni.com/events/J1DfAr2fGR3PCrN58guJQu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/H2fuxZZjSUSywzErXRfQo8 https://cassyni.com/events/J1DfAr2fGR3PCrN58guJQu?videoPreview=1 Laser-matter interactions at ultra-high intensity: how do we simulate them and what can experiments tell us?nohttps://cassyni.com/events/J1DfAr2fGR3PCrN58guJQu?videoPreview=12022-04-07T15:00:00+00:002808.88Journal of Plasma PhysicsAs the intensity frontier pushes past 10 23 W/cm -2 , experiments with high-intensity lasers interacting with matter, whether plasma or relativistic particle beams, enter a new regime. Here the dynamics arise from the interplay between relativistic plasma physics and strong-field, nonperturbative, quantum electrodynamics (QED). Understanding these processes is essential for developing our knowledge of extreme astrophysical environments, such as pulsars, magnetars and black-hole magnetospheres. In this talk I will present an overview of the progress that has been made in investigating the strong-field regime, from the simulation models we use, to the experiments that are possible with today's high-power lasers.https://cassyni-user-files-prod.s3.amazonaws.com/H2fuxZZjSUSywzErXRfQo8 https://cassyni.com/slides/outline/LUTgQGGHThosZnqdgNow8q https://cassyni.com/events/LUTgQGGHThosZnqdgNow8q/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KVuwByoMdmDUJviR57a3X4 https://cassyni.com/events/LUTgQGGHThosZnqdgNow8q?videoPreview=1 Investigating radiatively driven, magnetized plasmas with a university scale pulsed-power generatornohttps://cassyni.com/events/LUTgQGGHThosZnqdgNow8q?videoPreview=12022-08-25T15:00:00+00:002832.4Journal of Plasma PhysicsWe describe results from a novel experimental platform that is able to access physics relevant to topics including indirect-drive magnetized inertial confinement fusion, laser energy deposition, various topics in atomic physics, and laboratory astrophysics (for example, the penetration of B-fields into high energy density plasmas). This platform uses the x rays from a wire array Z-pinch to irradiate a silicon target, producing an outflow of ablated plasma. The ablated plasma expands into ambient, dynamically significant B-fields (∼5 T), which are supported by the current flowing through the Z-pinch. The outflows have a well-defined (quasi-1D) morphology, enabling the study of fundamental processes typically only available in more complex, integrated schemes. Experiments were fielded on the MAGPIE pulsed-power generator (1.4 MA, 240 ns rise time). On this machine, a wire array Z-pinch produces an x-ray pulse carrying a total energy of ∼15 kJ over ∼30 ns. This equates to an average brightness temperature of around 10 eV on-target.https://cassyni-user-files-prod.s3.amazonaws.com/KVuwByoMdmDUJviR57a3X4 https://cassyni.com/events/UsUxBtGCvVDrj8C6kE8zMj/abstract https://cassyni.com/events/XLiyRJVq7mzM64ffHv3d5f/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GXiTexFTa3iJjtnky11RTU https://cassyni.com/events/TtBk6WyA3a7i4NN6eFffYq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/P38MNESmePeixCzPLcebzN https://cassyni.com/events/6eJm789bAtJPvcNvmhTXQ1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/L6YugXQpYSRVrgwCwkyBnN https://cassyni.com/events/78xN9oo7cLrSvNupN8kKfK/abstract https://cassyni.com/slides/outline/BZj9E33AFke5nm7SgLanE1 https://cassyni.com/events/BZj9E33AFke5nm7SgLanE1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/jgoZ2gisP2xs34C86iYT8 https://cassyni.com/events/BZj9E33AFke5nm7SgLanE1?videoPreview=1 Comparative Outcomes of Hybrid Operating Room vs Conventional CT Suite Approaches for Pulmonary Nodule Localization and Thoracoscopic Resection in Childrennohttps://cassyni.com/events/BZj9E33AFke5nm7SgLanE1?videoPreview=12025-10-16T09:45:28+00:00546.68Society for Pediatric Interventional Radiology## Introduction CT-guided localization facilitates minimally invasive thoracoscopic resection of pulmonary nodules but traditionally requires transfer from the radiology suite to the operating room (CT+OR), introducing potential inefficiencies and safety concerns. We hypothesized that performing localization and resection under a single anesthetic within a hybrid operating room (HOR) equipped with cone beam CT improves procedural efficiency and reduces complication rates compared to the conventional CT+OR approach. ## Materials and Methods We conducted a retrospective review of pediatric oncology patients undergoing pulmonary nodule localization and resection between 2012 and 2024. Patients were grouped by localization technique: conventional CT+OR versus HOR. We compared localization times, transport durations, radiation doses, complication rates, and completion of thoracoscopic resections. ## Results A total of 126 procedures were analyzed (35 CT+OR; 91 HOR). Mean localization time was lower in the HOR group (31 vs 45 minutes). CT+OR cases required additional transport time (mean 55 minutes). Radiation dose per localization was similar across groups, adjusted for patient size. Thoracoscopic completion rates were comparable (91.4% vs 93.4%), but the HOR group demonstrated a lower complication rate (7.7% vs 11.4%). ## Discussion Compared to the conventional CT+OR workflow, use of a hybrid operating room for localization and resection of pulmonary nodules is associated with reduced localization time, elimination of interdepartmental transport, and fewer complications. These findings demonstrate that a HOR-based approach enhances procedural efficiency and patient safety in pediatric pulmonary nodule localization and thoracoscopic resection.https://cassyni-user-files-prod.s3.amazonaws.com/jgoZ2gisP2xs34C86iYT8 https://cassyni.com/events/Xp4K6PvhdH1LXhuDYzjne9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RXHRKvk768pn9EqYE3Cxvi https://cassyni.com/events/FWq7FcfhZLHgivoHw6cLTf/seminar/qa https://cassyni.com/slides/outline/FWq7FcfhZLHgivoHw6cLTf https://cassyni.com/events/FWq7FcfhZLHgivoHw6cLTf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CBFdVar8mU3kmtm3oyEdbL https://cassyni.com/events/FWq7FcfhZLHgivoHw6cLTf?videoPreview=1 Harrow Cardio Renal Metabolic hubsnohttps://cassyni.com/events/FWq7FcfhZLHgivoHw6cLTf?videoPreview=12025-10-14T10:15:00+00:001880.88North West London Kidney CareThe Harrow Cardio Renal Metabolic (CRM) hubs initiative addresses the interconnected progression of cardiovascular, renal, and metabolic conditions by implementing an integrated, patient-centered approach within primary care networks. The program targets early identification and management of metabolic syndrome components—including obesity, hypertension, diabetes, and chronic kidney disease (CKD)—across a population where up to 30–40% of adults are affected. Key methods include extended 30-minute consultations, use of SNOMED-coded questionnaires for upstream data capture, and alignment of clinical templates with evidence-based guidelines accessible via EMIS and SystmOne systems. Personalized care emphasizes partnership with patients, focusing on “what matters most” to them, and co-producing lifestyle plans addressing diet, physical activity, sleep, and social factors. Data-driven monitoring through CKD dashboards and monthly reports supports continuous evaluation and iterative refinement of the model. Results from over 2,600 patients show statistically significant improvements in blood pressure, HbA1c, waist circumference, and QRISK scores, with approximately 70% of participants improving in at least one clinical parameter. The approach also facilitates earlier detection of CKD and dyslipidemia, enhancing preventive care. The model’s scalability across multiple primary care networks and positive feedback from clinicians and patients underscore its feasibility and acceptability. This integrated CRM hub framework demonstrates potential to delay disease progression, improve quality of life, and inform future commissioning strategies for cardio-renal-metabolic health management.https://cassyni-user-files-prod.s3.amazonaws.com/CBFdVar8mU3kmtm3oyEdbL https://cassyni.com/events/4fD8s4HYAZQvc4fFbKqTrV/seminar/qa https://cassyni.com/slides/outline/4fD8s4HYAZQvc4fFbKqTrV https://cassyni.com/events/4fD8s4HYAZQvc4fFbKqTrV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CTMV1YqHMZ8xg3sgCs9SEi https://cassyni.com/events/4fD8s4HYAZQvc4fFbKqTrV?videoPreview=1 Added-Mass-Partitioned Solvers: Robust and Accurate Computational Methods for Fluid Structure Interactionnohttps://cassyni.com/events/4fD8s4HYAZQvc4fFbKqTrV?videoPreview=12023-05-15T14:00:00+00:003600.12Journal of Computational PhysicsFrom the design of aircraft and wind turbines to non-proliferation, technical and policy decisions are becoming increasingly reliant on computer simulation of complex multi-physics systems involving multiple interacting domains. In this talk I will discuss computational challenges associated with inter-domain coupling in the context of fluid-structure interaction (FSI). The discrete formulation of the fluid/solid interface conditions has a strong influence on the overall stability of the approach, and FSI solvers are historically found to su er when the so-called added-mass effects are large. These difficulties have their origin in the fact that the reaction of an immersed body to an applied force depends not only on the mass of the body but also on the mass of the fluid displaced by the body through its motion. Traditional approaches do not properly account for the fluid added mass, and can therefore experience a situation where the over-reaction of a light solid to an applied fluid force leads in turn to an even larger reaction from the fluid and so on. I will present recent work concerning the development and analysis of a new class of stable and accurate partitioned solvers that overcome added-mass instability through the use of so-called compatibility conditions. Schemes derived in this way are dubbed Added Mass Partitioned (AMP). Results will be presented for both compressible and incompressible flow regimes, and stability of the FSI coupling will be discussed using normal-mode stability theory.https://cassyni-user-files-prod.s3.amazonaws.com/CTMV1YqHMZ8xg3sgCs9SEi https://cassyni.com/events/FXURt6X5pdbQ8LVHCs59oK/seminar/qa https://cassyni.com/slides/outline/FXURt6X5pdbQ8LVHCs59oK https://cassyni.com/events/FXURt6X5pdbQ8LVHCs59oK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VNhGcEKrcuQMgn6v2ovLZk https://cassyni.com/events/FXURt6X5pdbQ8LVHCs59oK?videoPreview=1 Kidney Health for All – Preparing for the unexpected, supporting the vulnerable!nohttps://cassyni.com/events/FXURt6X5pdbQ8LVHCs59oK?videoPreview=12023-03-09T09:00:00+00:007571.2Dialysis GroupThe COVID pandemic was an unexpected stressor which heightened our professional awareness of vulnerability in our patients. It also revealed weaknesses in our dialysis care process. These vulnerabilities pre-existed the crisis and persist after it. We need to address health inequity as we recover and redesign dialysis care. I will discuss the literature on the effect of ethnicity, educational level, health literacy and socioeconomic status in the UK https://cassyni-user-files-prod.s3.amazonaws.com/VNhGcEKrcuQMgn6v2ovLZk https://cassyni.com/slides/outline/AbMUuSkMfk6uzBwShoxh4y https://cassyni.com/events/AbMUuSkMfk6uzBwShoxh4y/abstract https://cassyni-user-files-prod.s3.amazonaws.com/E7HHJs8eSyhM6mQ96cC25C https://cassyni.com/events/AbMUuSkMfk6uzBwShoxh4y?videoPreview=1 On Identity in Agonistic Engagementnohttps://cassyni.com/events/AbMUuSkMfk6uzBwShoxh4y?videoPreview=12022-12-09T00:30:00+00:004644.88SACLAgonistic engagement is an approach to dialogue and debate that takes seriously the role of power, difference and ideological conflict. Although change is often associated with individuals’ transition into ‘friendly enemies’ (Addis, 2001), the transformational potential of agonistic engagement is realised in the formation of chains of equivalence (Brown, 2009; Mouffe, 2000, 2013). As a learning process, agonistic engagement stimulates critical reflection amongst individuals as they challenge their identity and reflect on those with divergent perspectives, and it is in this process that previously unrecognised areas of shared interests and common understandings are surfaced that can link marginalised voices together in chains of equivalence to challenge hegemonic narratives (Mouffe, 2013). Prior research explored the construction of spaces for agonistic engagement (Bebbington et al, 2007; Brown & Dillard, 2013, 2015) as a way to analyse their impact (Aleksandrov et al, 2018; Belluci et al, 2019; Laine and Vinnari, 2017; Tanima et al., 2020), and even identified the importance of identity construction within them (Milne and Tregidga, 2020). However, relatively little consideration has been given to the role of individuals’ within this process, and it is here that this research aims to contribute. Using a post-structurally pluralist articulation of agonistic engagement (Brown, 2017), prior research is reviewed to illustrate how individuals’ identities are currently being represented (Aleksandrov et al, 2018; Laine and Vinnari, 2017; Tregidga and Milne, 2020; Tanima et al., 2020). These representations, and their limitations with regard to individuals, are then discussed. Ultimately, this paper aims to surface issues for future research to consider regarding the dynamic, intersubjective (Modell, 2015; 2017), (re)construction of individuals’ identities. https://cassyni-user-files-prod.s3.amazonaws.com/E7HHJs8eSyhM6mQ96cC25C https://cassyni.com/slides/outline/GXAMaH2YLbfpCXBC6q5TEd https://cassyni.com/events/GXAMaH2YLbfpCXBC6q5TEd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CjAk4VrvSYD1T6vAkHDNUE https://cassyni.com/events/GXAMaH2YLbfpCXBC6q5TEd?videoPreview=1 Keep the physics in the model if you can: Data assimilation in Fluid Mechanicsnohttps://cassyni.com/events/GXAMaH2YLbfpCXBC6q5TEd?videoPreview=12022-11-09T16:00:00+00:002840.0Department of AeronauticsThis talk will show how to assimilate data rigorously into physics-based models using Bayesian inference accelerated with adjoint methods. Adjoint methods are crucial because they provide the derivatives of the model's predictions with respect to the model's parameters. This (i) accelerates data assimilation and (ii) allows uncertainties to be propagated through the model such that posterior uncertainties in parameters are calculated by combining prior uncertainties with measurement uncertainties. Quantification of the uncertainties allows candidate physics-based models to be compared rigorously against each other, allowing the best model to be selected. If the physics of the problem is known, this method is almost certainly better than assimilating data into a Neural Network because physics-based models require less training data, are interpretable, and can extrapolate to situations that share the same physics. This work is inspired by [David MacKay's book](https://www.inference.org.uk/itprnn/book.pdf) on information theory, inference, and learning algorithms. I will present applications in Magnetic Resonance Imaging of flows (flow-MRI) and thermoacoustic oscillations in rockets and aicraft engines. An overview of the talk can be found on my [website](https://mpj1001.user.srcf.net/MJ_inference.html). https://cassyni-user-files-prod.s3.amazonaws.com/CjAk4VrvSYD1T6vAkHDNUE https://cassyni.com/slides/outline/BagK7SZHx28noRTr6MNTWV https://cassyni.com/events/BagK7SZHx28noRTr6MNTWV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WHVFQCpdb9rsr5rqaxBBYJ https://cassyni.com/events/BagK7SZHx28noRTr6MNTWV?videoPreview=1 Experimental investigation on the effect of forward-facing steps and gaps combined with wall suction on boundary layer transitionnohttps://cassyni.com/events/BagK7SZHx28noRTr6MNTWV?videoPreview=12022-03-29T14:00:00+00:00924.84Experiments in FluidsWall suction is known to be an effective Laminar Flow Control (LFC) technique to delay laminar-turbulent transition, but its commercial implementation is still limited due to design and integration issues. In particular, current design tools that model wall suction do not account for potential surface discontinuities that can arise during installation. However, these defects should be accounted for since they generally move transition further upstream, which could cancel drag reduction benefits from wall suction. Given this context, the present investigation aims at experimentally characterizing the combined effect of wall suction and two types of surface defects that can be found on aerodynamic surfaces, i.e., forward-facing steps (FFS) and gaps. Critical relative dimensions (at which transition occurs at the defect location) were different for each type of defect but remained unchanged regardless of whether wall suction was applied or not. For subcritical defects (defects where transition occurs further downstream of their location), wall suction could still delay transition, with reduced effectiveness. Spectral analysis inside the boundary layer revealed that the transition mechanism, governed by Tollmien–Schlichting instabilities, was unchanged in the presence of either critical or subcritical defects. The resulting increase in amplification of the existing instabilities due to either defect warranted the use of the ΔN model to capture this effect. Wall suction is therefore a robust LFC technique that can compete with the destabilizing effects of subcritical defects, albeit less effectively than in a smooth configuration. However, given the chosen suction flow rates, this technique could not delay or prevent the critical dimensions determined for cases without suction.https://cassyni-user-files-prod.s3.amazonaws.com/WHVFQCpdb9rsr5rqaxBBYJ https://cassyni.com/slides/outline/JVLS3ZtM41zg6mRZDSFRxh https://cassyni.com/events/JVLS3ZtM41zg6mRZDSFRxh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Be1guQ9a27y93aD8SogaCe https://cassyni.com/events/JVLS3ZtM41zg6mRZDSFRxh?videoPreview=1 RSE and development process updatesnohttps://cassyni.com/events/JVLS3ZtM41zg6mRZDSFRxh?videoPreview=12022-09-13T13:45:00+00:001634.48NEKTAR++No abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/Be1guQ9a27y93aD8SogaCe https://cassyni.com/events/Jyz36FXsVUYj6XxSosYEE1/seminar/qa https://cassyni.com/slides/outline/Jyz36FXsVUYj6XxSosYEE1 https://cassyni.com/events/Jyz36FXsVUYj6XxSosYEE1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Y92ppqVExH6UWawE5qTigv https://cassyni.com/events/Jyz36FXsVUYj6XxSosYEE1?videoPreview=1 The past, present and future of droughtnohttps://cassyni.com/events/Jyz36FXsVUYj6XxSosYEE1?videoPreview=12022-11-07T09:00:00+00:004024.88Nature WaterSeveral parts of the world have seen yet another dry summer. Understanding drought has become more relevant than ever. We’ll discuss the historical pattern of drought, drought monitoring, and the impact and future of drought with Monica Ionita (Alfred Wegener Institute), Andrea Toreti (European Commission's Joint Research Centre) and Luis Samaniego (Helmholtz-Centre for Environmental Research).https://cassyni-user-files-prod.s3.amazonaws.com/Y92ppqVExH6UWawE5qTigv https://cassyni.com/slides/outline/VMbj4c7ti6B9d3FapyV7uX https://cassyni.com/events/VMbj4c7ti6B9d3FapyV7uX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/SeseRoHZYwesFegbeXSfwc https://cassyni.com/events/VMbj4c7ti6B9d3FapyV7uX?videoPreview=1 Engineering interfacial flows and instabilities in solidifying liquidsnohttps://cassyni.com/events/VMbj4c7ti6B9d3FapyV7uX?videoPreview=12022-02-04T16:00:00+00:004168.48Journal of Fluid MechanicsThis talk is concerned with interfacial fluid mechanics in the context of solidifying liquids. Due to favorable downscaling with length, capillary effects are dominant for submillimetric objects and play a key role is a number of engineering and natural processes where they dictate the shape of drops, thin films, and coatings. As such, interfacial effects have been widely researched, albeit primarily in Newtonian fluids or in fluids whose constitutive law remains constant over time. In particular, the subtle interplay between hydrodynamics, solidification and the solid structures formed when harnessing capillary effects remain poorly understood. We will attempt to fill this gap of knowledge and study the physics of viscous jets and sheets in solidifying liquids. We will discuss experiments conducted with a model system, an elastomeric solution, so as to elucidate the competing phenomena at play in the formation of patterns and structures arising from interfacial flows and their subsequent or concomitant solidification. We will revisit classic fluid mechanics models, e.g. lubrication, and adapt them to situations where the flow is arrested in finite time. First, we will discuss droplet forming instabilities and show that the patterns they form can be engineered via the use of templates. New phenomena, e.g. self-templating, will be explored too. Second, we will revisit classic coating, drainage and imbibition problems and demonstrate that these flows can be used for materials design, e.g. fabricate soft robots. In fact, curing converts the flows we study into elastic solids, introducing the concept of “building with flows”.https://cassyni-user-files-prod.s3.amazonaws.com/SeseRoHZYwesFegbeXSfwc https://cassyni.com/slides/outline/Ru4VjpbDdtJWbLx2BK7ANh https://cassyni.com/events/Ru4VjpbDdtJWbLx2BK7ANh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/15YP7UkTwcwkEj8Gq3EAE2 https://cassyni.com/events/Ru4VjpbDdtJWbLx2BK7ANh?videoPreview=1 Noise reduction of serrated trailing edges with implicit large eddy simulation using PyFRnohttps://cassyni.com/events/Ru4VjpbDdtJWbLx2BK7ANh?videoPreview=12022-11-24T15:00:00+00:001840.92PyFRInspired by the silent flight ability of owls, the design of sawtooth trailing edges has been considered a promising way to control the interference noise when an incoming turbulent boundary layer passes through a sharp trailing edge. To this end, the flow and noise generation for different trailing-edge serrations are explored by the wall-resolved implicit large-eddy simulation (ILES) and acoustic analogy using PyFR. It was found that the size and shape of serrations could significantly affect noise reduction in the far field. The velocity profile and the distribution of Reynolds stress components show that the serrations mainly change the flow near the trailing edge and have little effect on the upstream flow. Furthermore, correlation analysis and dynamic mode decomposition (DMD) are used to confirm that destructive interference is the primary mechanism responsible for noise reduction. Since flow structures are reorganized near the TE serrations, we investigated the flow noise sources quantitatively in the near field. We found that the effect of vortex structures near the side edges of the serrations should be considered in the optimal design.https://cassyni-user-files-prod.s3.amazonaws.com/15YP7UkTwcwkEj8Gq3EAE2 https://cassyni.com/events/7d592XeoPwojpHyJSt6TD7/seminar/qa https://cassyni.com/slides/outline/7d592XeoPwojpHyJSt6TD7 https://cassyni.com/events/7d592XeoPwojpHyJSt6TD7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Qj1vhJSJKHw3mETSLH69CS https://cassyni.com/events/7d592XeoPwojpHyJSt6TD7?videoPreview=1 Deciphering the fingerprint of disturbance on the three-dimensional structure of the world’s forestsnohttps://cassyni.com/events/7d592XeoPwojpHyJSt6TD7?videoPreview=12022-11-16T15:00:00+00:002539.08New PhytologistCanopy gaps and the processes that generate them play an integral role in shaping the structure and dynamics of forests. However, it is only with recent advances in remote sensing technologies such as airborne laser scanning that studying canopy gaps at scale has become a reality. Consequently, we still lack an understanding of how the size distribution and spatial organization of canopy gaps varies among forests ecosystems, nor have we determined whether these emergent properties can be reconciled with existing theories of forest dynamics. Here, I outline a roadmap for integrating remote sensing with field data and individual-based models to build a comprehensive picture of how environmental constraints and disturbance regimes shape the three-dimensional structure of the world’s forests.https://cassyni-user-files-prod.s3.amazonaws.com/Qj1vhJSJKHw3mETSLH69CS https://cassyni.com/slides/outline/4AXuhk88Kjw6nbfjoDiVgH https://cassyni.com/events/4AXuhk88Kjw6nbfjoDiVgH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LrFo8mS9Pp9JX4c2RYXvWz https://cassyni.com/events/4AXuhk88Kjw6nbfjoDiVgH?videoPreview=1 A metamorphosis of three-dimensional wave structure in transitional and turbulent boundary layersnohttps://cassyni.com/events/4AXuhk88Kjw6nbfjoDiVgH?videoPreview=12021-05-14T15:00:00+00:001606.04Journal of Fluid MechanicsLaminar-turbulent transition in boundary layers is characterized by the generation and metamorphosis of flow structures. The early transition is usually associated with a process of the evolution from a three-dimensional (3-D) wave to a Λ-vortex. To develop a deeper understanding of the spatiotemporal wave-warping process and its roles in precipitating the development of other structures (e.g. hairpin-like structure and turbulent spot), we present numerical studies of both K-regime transition and bypass transition. In this talk, I will first illustrate a qualitative comparison of flow visualizations between a K-regime zero pressure gradient case and an adverse pressure gradient case, based on the method of Lagrangian tracking of marked particles. The underlying vortex dynamics will be presented using a proposed method of Lagrangian-averaged enstrophy. Next, I will draw attention to the 3-D wave structures in bypass transition and early turbulent boundary layer and will describe similar flow behaviours between transitional and turbulent boundary layers. Finally, I will discuss a path to transition, which hypothesizes that the amplification of a 3-D wave precipitates low-speed streaks and rotational structures in wall-bounded flows.https://cassyni-user-files-prod.s3.amazonaws.com/LrFo8mS9Pp9JX4c2RYXvWz https://cassyni.com/slides/outline/EY9bg6i9YMZXK6xspKfPMo https://cassyni.com/events/EY9bg6i9YMZXK6xspKfPMo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3XfbHZBhib6X9j2D1XSHzn https://cassyni.com/events/EY9bg6i9YMZXK6xspKfPMo?videoPreview=1 Light In complex Media: from imaging to computingnohttps://cassyni.com/events/EY9bg6i9YMZXK6xspKfPMo?videoPreview=12022-07-04T09:10:00+00:002291.04ETOPIMScattering of light in heterogeneous media, for instance the skin or a glass of milk, is usually considered an inevitable perturbation or even a nuisance. Through repeated scattering and interferences, this phenomenon seemingly destroys both the spatial andthe phase information of any laser illumination. At the spatial level, it gives rise to the well-known “speckle” interference patterns. At the temporal (or spectral) level, a short pulse entering a scattering medium will see its length greatly extended due to the multiplicity of possible path length light can take before exiting the medium. From an operative point of view, scattering greatly limits the possibility to image or manipulate an object with light through or in a scattering medium. Multiple scattering is a highly complex but nonetheless deterministic process: it is therefore reversible, in the absence of absorption. Speckle is coherent, and can be coherently controlled. By « shaping » or « adapting » the incident light, it is in principle possible to control the propagation and overcome the scattering process. This concept has been exploited in the last decade to focus and image through and in complex media, and opens important prospects for imaging at depth in biological media. I will present some recent work from the group illustrating this possibility, focusing on non-invasive fluorescence imaging, and leveraging computational imaging concepts. I will also show how the random mixing induced by the propagation of light through a complex medium can be leveraged for various computational tasks, allowing the intriguing concept of computing with disorder.https://cassyni-user-files-prod.s3.amazonaws.com/3XfbHZBhib6X9j2D1XSHzn https://cassyni.com/slides/outline/F2oCinMfyp7aJsVmQkxBd7 https://cassyni.com/events/F2oCinMfyp7aJsVmQkxBd7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8LzEVDk4zoVX8aQmtcrA62 https://cassyni.com/events/F2oCinMfyp7aJsVmQkxBd7?videoPreview=1 Wigner-Weyl description of radiative processes in correlated disordered semiconductor alloysnohttps://cassyni.com/events/F2oCinMfyp7aJsVmQkxBd7?videoPreview=12022-07-05T13:40:00+00:001233.04ETOPIMWe present a model for light absorption and luminescence in correlated semiconductor alloys based on an approach in phase space combined with the localization landscape. The model was recently shown to give reliable results at low computational cost for uncorrelated disordered InGaN alloys when compared with a model based on the direct solution of the Schr ̈odinger equation. We study the influence of compositional correlation on the absorption and spontaneous emission spectra.https://cassyni-user-files-prod.s3.amazonaws.com/8LzEVDk4zoVX8aQmtcrA62 https://cassyni.com/slides/outline/9bfZDGEu9n2Vv1FXoqxPdf https://cassyni.com/events/9bfZDGEu9n2Vv1FXoqxPdf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/S7jukcDMLhy9eHByzi7BEe https://cassyni.com/slides/outline/MwuHUyvuXao5xABk4mTZQR https://cassyni.com/events/MwuHUyvuXao5xABk4mTZQR/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2FhD2QrbgRSxYGGSMszTta https://cassyni.com/events/MwuHUyvuXao5xABk4mTZQR?videoPreview=1 Breakdown of light transport models in photonic scattering slabs with strong absorption and anisotropynohttps://cassyni.com/events/MwuHUyvuXao5xABk4mTZQR?videoPreview=12022-07-08T15:10:00+00:00553.04ETOPIMThe radiative transfer equation (RTE) models the transport of light inside photonic scattering samples such as paint, foam and tissue. Analytic approximations to solve the RTE fail for samples with strong absorption and dominant anisotropic scattering and predict unphysical negative energy densities and the diffuse flux in the wrong direction. Here we fully characterize the unphysical regions of three popular approximations to the RTE for a slab, namely the P1 approximation (or diffusion approximation), the P3 approximation, and a popular modification to P3 that corrects the forward scattering in the approximation. We find that the delta function correction to P3 eliminates the unphysical range in the forward scattering. In addition, we compare the predictions of these analytical methods to exact Monte Carlo simulations for the physical and unphysical regions. We present maps of relative errors for the albedo and the anisotropy of the scatterers for a realistic index contrast typical of a polymer slab in air and optical thickness.https://cassyni-user-files-prod.s3.amazonaws.com/2FhD2QrbgRSxYGGSMszTta https://cassyni.com/slides/outline/QR9JiQAXisZaK6fJcTNC8M https://cassyni.com/events/QR9JiQAXisZaK6fJcTNC8M/abstract https://cassyni-user-files-prod.s3.amazonaws.com/47X1bLg559wpgJGT83BkRL https://cassyni.com/events/QR9JiQAXisZaK6fJcTNC8M?videoPreview=1 Crossmodal Perception and Learning for Dexterous Service Robotsnohttps://cassyni.com/events/QR9JiQAXisZaK6fJcTNC8M?videoPreview=12022-11-04T03:00:00+00:003869.52Mechanical EngineeringRobot systems are needed to solve some real-world challenges by combining machine automation with realization of cognitive abilities in ICT systems. There has been substantial progress in deep neural networks and AI in terms of individual data-driven benchmarking, however, such existing data-driven systems are not yet crossmodal, they are not robust in a dynamic and changing world. My talk will first introduce concepts of cognitive systems which allows a robot to better understand multimodal scenarios by integration of knowledge and learning and then the necessary modules to enhance the robot intelligence level. Then I will explain how a robot can enhance its model as a result of learning from experiences; and how such cross-modal learning methods can be realized in intelligent robots, by demonstrating several novel robot systems with dexterous walking and manipulation skills in potential service applications. At the end, I will summarize the scientific challenges of cognitive systems in the framework of the NSFC/DFG Sino-German Collaborative Research Project TRR169 “Crossmodal Learning”.https://cassyni-user-files-prod.s3.amazonaws.com/47X1bLg559wpgJGT83BkRL https://cassyni.com/slides/outline/XpsNQesQJjsQogBmaLDvYM https://cassyni.com/events/XpsNQesQJjsQogBmaLDvYM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4dSXFYR56DbZftWHZf6PgA https://cassyni.com/events/XpsNQesQJjsQogBmaLDvYM?videoPreview=1 Relapse patterns and radiation dose exposure in IDH wild-type glioblastoma at first radiographic recurrence following chemoradiationnohttps://cassyni.com/events/XpsNQesQJjsQogBmaLDvYM?videoPreview=12022-11-28T21:00:00+00:001337.24Journal of Neuro-OncologyJoin Lenox Hill Neurosurgery and the Journal of Neuro-Oncology on Monday, November 28, for a conversation with Dr. Benjamin Ellingson, Dr. Akifumi Hagiwara, Dr. Satoka Shidoh, Dr. Nicholas Cho, Dr. Noriko Salamaon, and Dr. Ricky Savjani about their journal article on the relapse patterns and radiation dose exposure in IDH wide-type glioblastoma.https://cassyni-user-files-prod.s3.amazonaws.com/4dSXFYR56DbZftWHZf6PgA https://cassyni.com/events/SPjiu8kdUhnLQowXyRE8Yu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8eqQGNQEvMYXuSEepf8vt6 https://cassyni.com/slides/outline/StPKwpQ9vALPQaURZrWvpD https://cassyni.com/events/StPKwpQ9vALPQaURZrWvpD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/T52EJjvMQNvAoGWvFkKYFQ https://cassyni.com/events/StPKwpQ9vALPQaURZrWvpD?videoPreview=1 The Geometry of Linear Convolutional Networksnohttps://cassyni.com/events/StPKwpQ9vALPQaURZrWvpD?videoPreview=12022-03-24T16:00:00+00:003044.88DataSıgWe discuss linear convolutional neural networks (LCNs) and their critical points. We observe that the function space (that is, the set of functions represented by LCNs) can be identified with polynomials that admit certain factorizations, and we use this perspective to describe the impact of the network's architecture on the geometry of the function space. For instance, for LCNs with one-dimensional convolutions having stride one and arbitrary filter sizes, we provide a full description of the boundary of the function space. We further study the optimization of an objective function over such LCNs: We characterize the relations between critical points in function space and in parameter space and show that there do exist spurious critical points. We compute an upper bound on the number of critical points in function space using Euclidean distance degrees and describe dynamical invariants for gradient descent. This talk is based on joint work with Thomas Merkh, Guido Montúfar, and Matthew Trager.https://cassyni-user-files-prod.s3.amazonaws.com/T52EJjvMQNvAoGWvFkKYFQ https://cassyni.com/slides/outline/D4EQegHTdLpumQ1ifBAX5P https://cassyni.com/events/D4EQegHTdLpumQ1ifBAX5P/abstract https://cassyni-user-files-prod.s3.amazonaws.com/MtDPKZdLo56pWMagVtfuZp https://cassyni.com/events/D4EQegHTdLpumQ1ifBAX5P?videoPreview=1 Parametric estimation via MMD optimization: robustness to outliers and dependencenohttps://cassyni.com/events/D4EQegHTdLpumQ1ifBAX5P?videoPreview=12020-11-04T09:00:00+00:003443.16DataSıgIn this talk, I will study the properties of parametric estimators based on the Maximum Mean Discrepancy (MMD) defined by Briol et al. (2019). In a first time, I will show that these estimators are universal in the i.i.d setting: even in case of misspecification, they converge to the best approximation of the distribution of the data in the model, without ANY assumption on this model. This leads to very strong robustness properties. In a second time, I will show that these results remain valid when the data is not independent, but satisfy instead a weak-dependence condition. This condition is based on a new dependence coefficient, which is itself defined thanks to the MMD. I will show through examples that this new notion of dependence is actually quite general. This talk is based on published works, and works in progress, with Badr-Eddine Chérief Abdellatif (ENSAE Paris), Mathieu Gerber (University of Bristol), Jean-David Fermanian (ENSAE Paris) and Alexis Derumigny (University of Twente).https://cassyni-user-files-prod.s3.amazonaws.com/MtDPKZdLo56pWMagVtfuZp https://cassyni.com/events/C4wCZJzQkRim6eBiZChCGV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RJuVGBYW46N5qhGVMfzVLS https://cassyni.com/events/SQTusW9fx5sEDE3yQBdcy3/seminar/qa https://cassyni.com/slides/outline/SQTusW9fx5sEDE3yQBdcy3 https://cassyni.com/events/SQTusW9fx5sEDE3yQBdcy3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NxsoWNw87fHd7aJMqKZ4CN https://cassyni.com/events/SQTusW9fx5sEDE3yQBdcy3?videoPreview=1 The blushing brain: neural substrates of cheek temperature increase in response to self-observationnohttps://cassyni.com/events/SQTusW9fx5sEDE3yQBdcy3?videoPreview=12024-11-15T10:00:00+00:003019.04Royal Society PublishingDarwin proposed that blushing—the reddening of the face owing to heightened self-awareness—is ‘the most human of all expressions’. Yet, relatively little is known about the underlying mechanisms of blushing. Theories diverge on whether it is a rapid, spontaneous emotional response that does not involve reflection upon the self or whether it results from higher-order socio-cognitive processes. Investigating the neural substrates of blushing can shed light on the mental processes underlying blushing and the mechanisms involved in self-awareness. To reveal neural activity associated with blushing, 16–20 year-old participants (n = 40) watched pre-recorded videos of themselves (versus other people as a control condition) singing karaoke in a magnetic resonance imaging scanner. We measured participants’ cheek temperature increase—an indicator of blushing—and their brain activity. The results showed that blushing is higher when watching oneself versus others sing. Those who blushed more while watching themselves sing had, on average, higher activation in the cerebellum (lobule V) and the left paracentral lobe and exhibited more time-locked processing of the videos in early visual cortices. These findings show that blushing is associated with the activation of brain areas involved in emotional arousal, suggesting that it may occur independently of higher-order socio-cognitive processes. Our results provide new avenues for future research on self-awareness in infants and non-human animals.https://cassyni-user-files-prod.s3.amazonaws.com/NxsoWNw87fHd7aJMqKZ4CN https://cassyni.com/events/4fwKqRgadwVpQUmh26ExGd/seminar/qa https://cassyni.com/slides/outline/4fwKqRgadwVpQUmh26ExGd https://cassyni.com/events/4fwKqRgadwVpQUmh26ExGd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5SyWy2gt6KrThZSNBfHwmp https://cassyni.com/events/4fwKqRgadwVpQUmh26ExGd?videoPreview=1 Integral theorems for the gradient of a vector field, with a fluid dynamical applicationnohttps://cassyni.com/events/4fwKqRgadwVpQUmh26ExGd?videoPreview=12024-10-10T14:00:00+00:003384.84Royal Society PublishingThe familiar divergence and Kelvin–Stokes theorem are generalized by a tensor-valued identity that relates the volume integral of the gradient of a vector field to the integral over the bounding surface of the tensor product of the vector field with the exterior normal. The importance of this long-established yet relatively little-known result is discussed. In flat two-dimensional space, it reduces to a relationship between an integral over an area and that over its bounding curve, combining the two-dimensional divergence and Kelvin–Stokes theorems together with two related theorems involving the strain, as is shown through a decomposition using a suitable tensor basis. A fluid dynamical application to oceanic observations along the trajectory of a moving platform is given. The potential extension of the generalized two-dimensional identity to curved surfaces is considered and is shown not to hold. Finally, the paper includes a substantial background section on tensor analysis, and presents results in both symbolic notation and index notation in order to emphasize the correspondence between these two notational systems.https://cassyni-user-files-prod.s3.amazonaws.com/5SyWy2gt6KrThZSNBfHwmp https://cassyni.com/events/C5fPXgPTDooeu4J9yy6ggd/seminar/qa https://cassyni.com/slides/outline/C5fPXgPTDooeu4J9yy6ggd https://cassyni.com/events/C5fPXgPTDooeu4J9yy6ggd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UbB3pAfcoWNyAuU1YydMNE https://cassyni.com/events/C5fPXgPTDooeu4J9yy6ggd?videoPreview=1 Plant Pathology Perspectives on Addressing SDG 1: No Povertynohttps://cassyni.com/events/C5fPXgPTDooeu4J9yy6ggd?videoPreview=12024-11-19T15:00:00+00:004546.04Springer Nature Sustainable Development Goals ProgrammeIn this webinar, our speakers, Kathy Kahn and Justin Pita, will highlight how advancements in plant pathology and epidemiology can contribute to achieving SDG 1: No Poverty, highlighting the WAVE initiative focused on cassava viruses. The WAVE Regional Center of Excellence is a scientific and technical platform that aims to increase food production in Central and West Africa, in a sustainable manner, by developing effective methods for the control and management of transboundary plant pathogens, as well as preventing the incursion of exotic plant diseases into new areas. We aim to inspire others to join the research for more sustainable and resilient crop production. The presentations will be followed by a panel discussion and Q&A session. Image credit: [Marvellous Omosola (Unsplash)](https://unsplash.com/photos/a-close-up-of-a-green-leafy-plant-U_atDCP3OxI).https://cassyni-user-files-prod.s3.amazonaws.com/UbB3pAfcoWNyAuU1YydMNE https://cassyni.com/events/HWpf9q27TCpnBFACEztMVo/seminar/qa https://cassyni.com/slides/outline/HWpf9q27TCpnBFACEztMVo https://cassyni.com/events/HWpf9q27TCpnBFACEztMVo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AkwmDNtmozovmADpu72Aer https://cassyni.com/events/HWpf9q27TCpnBFACEztMVo?videoPreview=1 Women of science in the circle of Sir John Frederick William Herschelnohttps://cassyni.com/events/HWpf9q27TCpnBFACEztMVo?videoPreview=12024-11-22T14:30:00+00:006908.36Royal Society PublishingJohn Herschel had a wide circle of erudite female friends, something his wife Margaret found initially intimidating but also very impressive. When raising their 9 daughters, they often looked to these women for inspiration and advice. As their confidence grew, they asked some of these women to be godmother to their younger girls, ensuring their daughters had as much help as possible to become themselves highly educated and outspoken, just like their impressive godmothers. Sir John Herschel engaged in enthusiastic correspondence with women of science, encouraging their experimental endeavours. In this talk I focus on his correspondence with three women : Anna Atkins, Julia Margaret Cameron, and Mary Somerville. Herschel’s letters impart photographic knowledge to Somerville and guidance to Cameron, becoming her subject in the 1867 portrait of ‘old paterfamilias’. Although there are no preserved letters between Anna Atkins and Sir John Herschel at The Royal Society, her adoption of cyanotype photography ensured his 1842 discovery was comprehensively demonstrated as the basis for an innovative visual record of British algae. The talk includes brief reference to another female correspondent, poet Elizabeth Colling, and concludes that Herschel’s support for women gave valuable recognition for their creative or scientific skills; a rare gift of equal opportunity. This talk delves into the spectral experimentation of the 1840s in the context of Mary Somerville's work, following a series of experiments conducted by Sir John F. W. Herschel that investigated the interaction of light and botanical matter. By re-performing the historical experiments, the material culture and tacit knowledge of the experiments are discussed, as well as how they were situated within discourses on the nature of light and colour. Although spectral analysis had standard materials, the way it was put into practice was highly individual. This led to unique results for each experimenter, demonstrating the complexity of reasoning about the fundamental workings of nature when working with the volatile colour changes of botanical matter. This talk provides the context for a set of letters between Augusta Ada King, Countess of Lovelace (1815–1852) and Sir John Frederick William Herschel (1792–1871) found in the Royal Society archives. The 1848 letters reveal little-known facets of her scientific pursuits: her interest in the application of photography to meteorological instrumentation, her budding study of astronomy, and her development of mathematical treatments to model the environmental conditions required for plants to grow. The exchange situates Ada Lovelace in the larger context of Victorian science and reflects more widely on the complicated access of women to institutional science.https://cassyni-user-files-prod.s3.amazonaws.com/AkwmDNtmozovmADpu72Aer https://cassyni.com/slides/outline/Vs2mJvCERefe4vQ1DMT5dw https://cassyni.com/events/Vs2mJvCERefe4vQ1DMT5dw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UDZ9MVCpTRZT7CyUqeFqot https://cassyni.com/events/Vs2mJvCERefe4vQ1DMT5dw?videoPreview=1 Deciphering One Health microbiomes using field-deployable biosensorsnohttps://cassyni.com/events/Vs2mJvCERefe4vQ1DMT5dw?videoPreview=12024-11-05T03:00:00+00:003283.04The Auckland Bioengineering InstituteMicrobiomes play a vital role in the health of plants, animals, humans, and the environment (One Health). Characterizing microbiomes typically requires lab-based techniques such as polymerase chain reaction (PCR) or next-generation sequencing (NGS), which are slow, labor-intensive, and expensive. Developing biosensors that can characterize microbiomes in the field can enable rapid turnaround and allow stakeholders to make quick decisions. We present a novel biosensor platform for field-deployable microbiome characterization. Our biosensors are based on loop-mediated isothermal amplification (LAMP) on microfluidic paper-based analytical devices (μPADs). LAMP is a rapid and sensitive nucleic acid amplification technique that does not require specialized equipment, making it ideal for field use. μPADs are portable, low-cost, and easy-to-use devices that can be used to perform complex assays without the need for electricity or specialized training. We demonstrate the use of our biosensors to detect bacteria and viruses with high analytical sensitivity and specificity (>~90%). We also show that our biosensors can be used to characterize microbiomes in animal and plant farms. For example, we have used our biosensors to detect bacteria associated with bovine respiratory disease in cattle feedlot and to quantify the levels of Bacteroidales as fecal indicators around fresh produce operations. Our biosensors have the potential to transform how microbiomes are characterized in the field. They can be used to monitor animal and plant health, ensure food safety, and diagnose human diseases. Our biosensors are also affordable and easy-to-use, making them accessible to a wide range of users. https://cassyni-user-files-prod.s3.amazonaws.com/UDZ9MVCpTRZT7CyUqeFqot https://cassyni.com/events/TPnk5VxcEMu72mADkZeidj/seminar/qa https://cassyni.com/slides/outline/TPnk5VxcEMu72mADkZeidj https://cassyni.com/events/TPnk5VxcEMu72mADkZeidj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Q1P3f6ciAQJKicQsegW5Nv https://cassyni.com/events/TPnk5VxcEMu72mADkZeidj?videoPreview=1 Actionable Primary Care: Translational Research Toward Public Health Impactnohttps://cassyni.com/events/TPnk5VxcEMu72mADkZeidj?videoPreview=12025-05-01T20:00:00+00:003314.84Family MedicineAt the end of this session, attendees will be able to: 1. Describe translational research categories, especially those most relevant to primary care 1. Discuss primary care’s role in actionable research 1. Describe the potential impact of primary care research on the health of individuals and communitieshttps://cassyni-user-files-prod.s3.amazonaws.com/Q1P3f6ciAQJKicQsegW5Nv https://cassyni.com/slides/outline/3C28p1FtivmCs5QNpnMRDP https://cassyni.com/events/3C28p1FtivmCs5QNpnMRDP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TnCWkbRLW69KJmdyXEbDPL https://cassyni.com/events/3C28p1FtivmCs5QNpnMRDP?videoPreview=1 Adjoint-Based Deep Learning for Flow Prediction and Controlnohttps://cassyni.com/events/3C28p1FtivmCs5QNpnMRDP?videoPreview=12024-10-28T14:00:00+00:003282.28Department of Aeronautics and AstronauticsPrediction and control of complex flows remain a significant challenge for engineering systems. Turbulent flow predictions generally require Reynolds-Averaged Navier–Stokes (RANS) simulations and Large-Eddy Simulation (LES), though their predictive accuracy can be insufficient for flow control optimization, and non-Boussinesq turbulence and/or unresolved multiphysical phenomena can preclude qualitative fidelity in certain regimes. For example, in turbulent combustion, flame–turbulence interactions can lead to inverse-cascade energy transfer, which violates the assumptions of many RANS and LES closures. We develop adjoint-based, solver-embedded data assimilation methods to augment the RANS and LES equations using trusted data and embedded higher-fidelity simulations. This is accomplished using Python-native flow solvers that leverage differentiable programming techniques to construct the adjoint equations needed for optimization. We present applications to canonical turbulence, shock-dominated flows, aerothermodynamics, and flow control and discuss the potential of adjoint-based approaches for future machine learning applications.https://cassyni-user-files-prod.s3.amazonaws.com/TnCWkbRLW69KJmdyXEbDPL https://cassyni.com/events/DZdpnMquwYPdPahWqtJJtu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/G8bPrqaWe64nrXcTyns38a https://cassyni.com/slides/outline/Kz6JVsmd3rX3Mt6NzMdA8d https://cassyni.com/events/Kz6JVsmd3rX3Mt6NzMdA8d/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7SXBpNAZwb1PwtFPSPfJHk https://cassyni.com/events/Kz6JVsmd3rX3Mt6NzMdA8d?videoPreview=1 Flex Fund Case Study: Access to Capital for Minoritized Small Businessesnohttps://cassyni.com/events/Kz6JVsmd3rX3Mt6NzMdA8d?videoPreview=12024-11-20T14:00:00+00:00556.6Center for Black Entrepreneurship, Spelman CollegeThe Atlanta Flex Fund case study reveals transformative approaches to reducing barriers to capital for underrepresented entrepreneurs. The study underscores the potential of targeted interventions to empower diverse entrepreneurs and foster a more inclusive economy. Unlike traditional underwriting methods that prioritize credit scores and credit history, the Flex Fund introduced an innovative evaluation model. By focusing on business viability, cash flow, and debt-to-equity ratios, alongside robust pre- and post-loan technical assistance, the program redefined how risk is assessed, and loans are awarded. Early data seem to imply that zero interest debt micro fund might be an innovative strategy to reduce systemic barriers for access to capital for under resourced entrepreneurs. Pre and post loan technical assistance provided critical preparation, enhancing applicants' readiness and success in securing funding. A simplified loan application process significantly boosted confidence levels among underserved business owners.https://cassyni-user-files-prod.s3.amazonaws.com/7SXBpNAZwb1PwtFPSPfJHk https://cassyni.com/events/8dBQS9tYxKn45e7EdNBP7j/seminar/qa https://cassyni.com/slides/outline/8dBQS9tYxKn45e7EdNBP7j https://cassyni.com/events/8dBQS9tYxKn45e7EdNBP7j/abstract https://cassyni-user-files-prod.s3.amazonaws.com/N89jKKnfsBjipNo4KHtjtr https://cassyni.com/events/8dBQS9tYxKn45e7EdNBP7j?videoPreview=1 AI and the Visualization of Paradise: Cultural Paradigms, Aesthetic Evolution, and Cognitive Exploration, From Varanasi to Sinaia - 3rd and 4th World Congresses on Logic and Religion, Proposal for organizing the 5th Congress on Logic and Religion in Vancouver, July 6-10, 2025nohttps://cassyni.com/events/8dBQS9tYxKn45e7EdNBP7j?videoPreview=12024-12-18T15:00:00+00:006323.08Logica UniversalisThis study investigates the intricate process of visualizing the concept of paradise through the lens of Artificial Intelligence (AI), employing neural networks to craft intricate visual depictions of utopian realms. The project scrutinizes the prevalent themes associated with paradisiacal imagery, dissecting the intricate weave of religious doctrines, mythologies, and the intrinsic nature of paradise – be it a tangible realm or a metaphysical state. This inquiry critically assesses the role of AI-generated art, derived from complex algebraic formulations, in mirroring conventional iconography and exposing inherent biases. Such revelations underscore the cultural resonance of diverse traditions and the potential presence of subconscious prejudices. Employing AI algorithms capable of transforming textual prompts into vivid illustrations, this research unveils insights into the nexus of AI and cultural portrayals of utopia, thereby provoking profound philosophical deliberations. Central to these contemplations is the extent of human dominion over conceptualized ideals and the prospect of AI-crafted art inadvertently molding our paradisiacal perceptions, with implications ranging from reinforcement of stereotypes to shaping intrinsic cognitive schemas. This talk discusses the development of the Logic and Religion project and the various events organized within this framework, particularly the 3rd and 4th editions, with this volume including papers presented at both.https://cassyni-user-files-prod.s3.amazonaws.com/N89jKKnfsBjipNo4KHtjtr https://cassyni.com/events/WMhzUEMeGU9TtPPX1Ta3p9/seminar/qa https://cassyni.com/slides/outline/WMhzUEMeGU9TtPPX1Ta3p9 https://cassyni.com/events/WMhzUEMeGU9TtPPX1Ta3p9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/31m6SzmP5Nmri4SuVU1AHC https://cassyni.com/events/WMhzUEMeGU9TtPPX1Ta3p9?videoPreview=1 Data Accessibility to Enable African Data Science, ML and AI for Healthnohttps://cassyni.com/events/WMhzUEMeGU9TtPPX1Ta3p9?videoPreview=12024-11-28T16:00:00+00:003799.04NoneAfrican healthcare faces significant challenges in adopting artificial intelligence and machine learning technologies, primarily due to limitations in data accessibility. This presentation argues for a "3IR before 4IR" approach, emphasizing the need to establish fundamental data infrastructure before pursuing advanced AI applications. Key barriers include lack of digitized health systems, infrastructure constraints, funding limitations, and governance challenges. The presentation outlines a multi-layered solution incorporating secure data environments, privacy-preserving methods, and federated analysis approaches like OMOP (Observational Medical Outcomes Partnership).https://cassyni-user-files-prod.s3.amazonaws.com/31m6SzmP5Nmri4SuVU1AHC https://cassyni.com/slides/outline/WrMbWv1AhvhWt9vQbtrr5T https://cassyni.com/events/WrMbWv1AhvhWt9vQbtrr5T/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HuYoEKFY8mv37SrBERWsLa https://cassyni.com/events/WrMbWv1AhvhWt9vQbtrr5T?videoPreview=1 Out of one, many: creating broadband spectra of oceanic internal wavesnohttps://cassyni.com/events/WrMbWv1AhvhWt9vQbtrr5T?videoPreview=12024-11-21T12:00:00+00:003547.56The Edinburgh Fluid Dynamics Group (EFDG)Internal gravity waves, which owe their existence to a combination of stratification and the Earth’s rotation, are known to contribute significantly to vertical mixing and the functioning of the global ocean circulation, yet they are far too small and too fast to be resolvable in climate models. This means we rely on theory and simple parameterizations to model their impact on the resolved flow in these models. A persistent theory challenge has been to explain observed broadband wave spectra even though the dominant internal wave sources are known to be nearly monochromatic. Nonlinear processes such as wave--wave or wave--current interactions are therefore essential to explain the observations. In particular, wave turbulence theory based on resonant wave--wave interactions has long been a candidate for this problem, but the practical problems of applying this theory to a non-isotropic, non-canonical fluid dynamics system have been immense. In this talk, I will introduce these issues and then discuss recent advances in wave turbulence theory that greatly simplified its application to internal waves and led to predicted wave spectra that are arguably much closer to the observations than indicated by previous work. Image credit: [Richard R. Schünemann (Unsplash)](https://unsplash.com/photos/a-close-up-of-a-blue-water-surface-3QsFMZLm_KU).https://cassyni-user-files-prod.s3.amazonaws.com/HuYoEKFY8mv37SrBERWsLa https://cassyni.com/events/3ghMyKRJZkF2gYPtctUPPb/seminar/qa https://cassyni.com/slides/outline/3ghMyKRJZkF2gYPtctUPPb https://cassyni.com/events/3ghMyKRJZkF2gYPtctUPPb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CVvg1dRkidvTnm2DEdQTC2 https://cassyni.com/events/3ghMyKRJZkF2gYPtctUPPb?videoPreview=1 Advancing Scientific Machine Learning in Industrynohttps://cassyni.com/events/3ghMyKRJZkF2gYPtctUPPb?videoPreview=12025-03-26T13:00:00+00:003520.04MOX Laboratory - Department of MathematicsScientific machine learning (SciML) has been taking the academic world by storm as an interesting blend of traditional scientific modeling with machine learning (ML) methodologies like deep learning. While traditional machine learning methodologies have difficulties with scientific issues like interpretability, and enforcing physical constraints, the blend of ML with numerical analysis and differential equations has evolved into a novel field of research which overcome these problems while adding the data-driven automatic learning features of modern machine learning. Many successes have already been demonstrated, with tools like physics-informed neural networks, universal differential equations, deep backward stochastic differential equation solvers for high dimensional partial differential equations, and neural surrogates showcasing how deep learning can greatly improve scientific modeling practice. Consequently, SciML holds promise for versatile application across a wide spectrum of scientific disciplines, ranging from the investigation of subatomic particles to the comprehension of macroscopic systems like economies and climates. However, despite notable strides in enhancing the speed and accuracy of these methodologies, their utility in practical and specifically industrial settings remain constrained. Many domains within the scientific community still lack comprehensive validation and robustness testing of SciML approaches. This limitation is particularly pronounced when confronted with complex, real-world datasets emanating from interactions between machinery and environmental sensors as usually addressed in industry. Still if appropriately addressed, SciML with its promise to accelerate innovations and scientific discoveries by orders of magnitudes, offers unique opportunities to address the insatiable desire for faster and more accurate predictions in many fields. This presentation is dedicated to exploring recent advancements in the implementation of SciML techniques. We will discuss how methodologies can be refined to ensure their practical viability and scalability, particularly in industrial sectors where digital and physical components converge. https://cassyni-user-files-prod.s3.amazonaws.com/CVvg1dRkidvTnm2DEdQTC2 https://cassyni.com/events/6eccN3pLbrVPYAdBsnPia1/seminar/qa https://cassyni.com/slides/outline/6eccN3pLbrVPYAdBsnPia1 https://cassyni.com/events/6eccN3pLbrVPYAdBsnPia1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/ApxUXcyktqq49gsrhbBJ2J https://cassyni.com/events/6eccN3pLbrVPYAdBsnPia1?videoPreview=1 Breaking Free: From Resiliency to Identity-Rewriting the Script of Disability in American Higher Educationnohttps://cassyni.com/events/6eccN3pLbrVPYAdBsnPia1?videoPreview=12025-04-24T16:00:00+00:003307.24Lived Places PublishingAbleism is a systemic issue that continues to plague American postsecondary education – but educators can help break the cycle of ableism and promote inclusiveness. Stephanie’s path to acceptance of her disability was not an easy journey. Her disability manifested at the impressionable ages of 20 and 22 which led to a conflict in her identity as an undergraduate student and, later, as a graduate student. Now fully accepting of her identity as a visually impaired woman, Stephanie reflects on the peaks and valleys that plagued her journey to acceptance. She discusses not only how she experienced ableism within the context of American higher education but also how she endured internalized ableism within herself. She also provides further insight into the models of disability identity and how these models ultimately shape the identities of higher education students. Understanding that ableism is a systemic issue that continues to plague American postsecondary education, Stephanie provides an overview of disability history within higher education. After reflecting on the history of disability in American higher education, she discusses ways in which educators can break the cycle of ableism and further promote inclusiveness within their institutions. https://cassyni-user-files-prod.s3.amazonaws.com/ApxUXcyktqq49gsrhbBJ2J https://cassyni.com/events/B6RRfa8B9cYsB7vMamL7ob/seminar/qa https://cassyni.com/slides/outline/B6RRfa8B9cYsB7vMamL7ob https://cassyni.com/events/B6RRfa8B9cYsB7vMamL7ob/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WTLYzGcgHdqo7xzbNoa78A https://cassyni.com/events/B6RRfa8B9cYsB7vMamL7ob?videoPreview=1 From experiments to computational models of the fast and slow lanes of the cardiac vagusnohttps://cassyni.com/events/B6RRfa8B9cYsB7vMamL7ob?videoPreview=12025-02-04T03:00:00+00:002994.04The Auckland Bioengineering InstituteThe vagus nerve is a key mediator of cardiovascular health. Vagal outflow stems from the brainstem and reaches the heart at the intrinsic cardiac nervous system (ICN), the heart’s “little brain”. Due to the disparate, multi-scale nature of the anatomical, molecular, and physiological data on the cardiac vagus, data-derived mechanistic insights have proven elusive. Building on our recent results on spatially-tracked, single-cell transcriptomic atlases of the rat DMV and the rat and pig ICN, we developed an integrative computational modeling framework for combining these data with physiology data . These data were used to develop a computational library of neuronal electrophysiological models. The computational approach bridges the gap between abundant molecular-level gene expression and sparse cellular-level electrophysiology for studying the role of the ICN in cardiac function. Cellular-scale computational models built from these data sets represent building blocks that can be combined using anatomical and neural circuit connectivity, neuronal electrophysiology, and organ/organismal-scale physiology data to create multi-scale models that enable in silico exploration. We used a computational model-based approach that accounts for the short-term dynamics of closed-loop human cardiac control. Our model integrates disparate experimental studies on neural adaptation following myocardial infarction (MI) into a unified quantitative framework using an in silico patient cohort. The insights from the computational modelling and analyses will guide new experimental questions towards exploiting targeted vagal neuromodulatory activity to promote heart health.https://cassyni-user-files-prod.s3.amazonaws.com/WTLYzGcgHdqo7xzbNoa78A https://cassyni.com/slides/outline/LUmXfBw2tfzsBM5tnTk8Jq https://cassyni.com/events/LUmXfBw2tfzsBM5tnTk8Jq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JCvNL7i2vFEBdwZep6cVB4 https://cassyni.com/events/LUmXfBw2tfzsBM5tnTk8Jq?videoPreview=1 Photocatalytic water splitting for solar-to-chemical energy conversion and storagenohttps://cassyni.com/events/LUmXfBw2tfzsBM5tnTk8Jq?videoPreview=12025-02-26T11:00:00+00:005232.56Frontiers in Science### Advances in green hydrogen technology Explore new technologies in solar water splitting to create cost-effective renewable hydrogen and meet global energy demands. This event builds on a [*Frontiers in Science* lead article](https://www.frontiersin.org/journals/science/articles/10.3389/fsci.2024.1411644/full) outlining recent advances in solar water-splitting systems for developing photocatalysts with high solar-to-hydrogen energy conversion efficiency, artificial photosynthesis, and safe reactor design. You’ll hear from the article authors and other experts on the further research and regulatory frameworks needed for large-scale deployment of these technologies, to end our reliance on fossil fuels. [Register here](https://events.frontiersin.org/photocatalytic-water-splitting/C)https://cassyni-user-files-prod.s3.amazonaws.com/JCvNL7i2vFEBdwZep6cVB4 https://cassyni.com/slides/outline/i8ZuDM6DGxN94uqsJgiqs https://cassyni.com/events/i8ZuDM6DGxN94uqsJgiqs/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LSnFt6hVYd3YjJxK1wrwgi https://cassyni.com/events/i8ZuDM6DGxN94uqsJgiqs?videoPreview=1 High Fidelity Simulations in Support of Analysis and Design of Aircraft Enginesnohttps://cassyni.com/events/i8ZuDM6DGxN94uqsJgiqs?videoPreview=12024-12-07T17:00:00+00:001784.96JKW Symposium Teamnull Image credit: [Luka Slapnicar (Unsplash)](https://unsplash.com/photos/black-and-white-airliner-turbine-yqeXLR81Uj0).https://cassyni-user-files-prod.s3.amazonaws.com/LSnFt6hVYd3YjJxK1wrwgi https://cassyni.com/events/E4Lg4JXDBioE2k9eqfFSz1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/E3Y32Bi1rrSgF1mBt9XhBk https://cassyni.com/events/PwLP6bybNEoH2jr5dnxFkZ/seminar/qa https://cassyni.com/slides/outline/PwLP6bybNEoH2jr5dnxFkZ https://cassyni.com/events/PwLP6bybNEoH2jr5dnxFkZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5JzBHjeWVbwBApxwJ3n89C https://cassyni.com/events/PwLP6bybNEoH2jr5dnxFkZ?videoPreview=1 Consequence, Signification and Insolubles in Fourteenth-Century Logicnohttps://cassyni.com/events/PwLP6bybNEoH2jr5dnxFkZ?videoPreview=12025-03-26T15:00:00+00:005553.04Logica UniversalisForty years ago, Niels Green-Pedersen listed five different accounts of valid consequence, variously promoted by logicians in the early fourteenth century and discussed by Niels Drukken of Denmark in his commentary on Aristotle's Prior Analytics, written in Paris in the late 1330s. Two of these arguably fail to give defining conditions: truth preservation was shown by Buridan and others to be neither necessary nor sufficient; incompatibility of the opposite of the conclusion with the premises is merely circular if incompatibility is analysed in terms of consequence. Buridan proposed to define consequence in terms of preservation of signifying as things are. John Mair pinpointed a sophism which threatens to undermine this proposal. Speaking anachronistically, Bradwardine turned it around: he suggested that a necessary condition on consequence was that the premises signify everything the conclusion signifies. Dumbleton gave counterexamples to Bradwardine's postulates in which the conclusion arguably signifies more than, or even completely differently from the premises. Yet a long-standing tradition held that some species of validity depend on the conclusion being in some way contained in the premises. We explore the connection between signification and consequence and its role in solving the insolubles.https://cassyni-user-files-prod.s3.amazonaws.com/5JzBHjeWVbwBApxwJ3n89C https://cassyni.com/events/RuvoHLZh85238T8JzkpCB7/seminar/qa https://cassyni.com/slides/outline/RuvoHLZh85238T8JzkpCB7 https://cassyni.com/events/RuvoHLZh85238T8JzkpCB7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/S3gj4V2iGyatjD8X8E5EXp https://cassyni.com/events/RuvoHLZh85238T8JzkpCB7?videoPreview=1 Use of Quality-of-Life Indicators in the Health Sector - Patient Care Planning Toolsnohttps://cassyni.com/events/RuvoHLZh85238T8JzkpCB7?videoPreview=12025-03-29T08:00:00+00:004308.84The Open Public Health JournalThe aim of the webinar is to familiarize participants with the concept of quality of life and its objective and subjective dimensions. The methodology for assessing and measuring quality of life will be presented, with reference to the main tools used in the health and mental health sectors. Particular emphasis will be given to the presentation of research data from Greece and abroad, on the subject of measuring quality of life in patients with chronic diseases. In addition, participants will be introduced to the Missoula Vitas Quality of Life Index (MVQOLI) 15 question tool, which has been translated and culturally adapted to different languages, as well as the Disease Index, which evaluates the experience of the person who is ill, both from the perspective of the sufferer and from the perspective of the observer (family or friends) and the health professional. Finally, the Treatment Index will be presented, which assesses the effects of treatment on the patient's quality of life, emphasizing how interventions can improve or worsen the patient's daily life. **Don't miss the opportunity to enrich your knowledge on a topic of vital importance to healthcare!**https://cassyni-user-files-prod.s3.amazonaws.com/S3gj4V2iGyatjD8X8E5EXp https://cassyni.com/events/UPApWkoKKMnXVPbsYSipu3/seminar/qa https://cassyni.com/slides/outline/UPApWkoKKMnXVPbsYSipu3 https://cassyni.com/events/UPApWkoKKMnXVPbsYSipu3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HQYr5XxPhZpk3rWJhtyyze https://cassyni.com/events/UPApWkoKKMnXVPbsYSipu3?videoPreview=1 Emerging Trends in Organic Materialsnohttps://cassyni.com/events/UPApWkoKKMnXVPbsYSipu3?videoPreview=12025-05-07T13:00:00+00:005522.32Thieme GroupJoin us for the Thieme Cheminar: Emerging Trends in Organic Materials. Explore the forefront of organic materials research in this live online seminar featuring leading scientists. Gain insights into the latest developments and engage with experts during interactive Q&A sessions. Speakers: Prof. Pol Besenius (Johannes-Gutenberg-University Mainz, Germany) Prof. Ognjen Miljanic (University of Houston, USA) Prof. Irena Stará (Czech Academy of Sciences, Czech Republic) Prof. Max von Delius (Ulm University, Germany)https://cassyni-user-files-prod.s3.amazonaws.com/HQYr5XxPhZpk3rWJhtyyze https://cassyni.com/events/EZ1uDcgd2YH3rD9AdmNRAD/seminar/qa https://cassyni.com/slides/outline/EZ1uDcgd2YH3rD9AdmNRAD https://cassyni.com/events/EZ1uDcgd2YH3rD9AdmNRAD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7nFKDxjgQKxrPAbvc9kn9c https://cassyni.com/events/EZ1uDcgd2YH3rD9AdmNRAD?videoPreview=1 An Interactional Sociolinguistic Approach to Identity Construction among Non-Māori Participants in Te Reo Māori Revitalisationnohttps://cassyni.com/events/EZ1uDcgd2YH3rD9AdmNRAD?videoPreview=12025-07-11T01:10:00+00:003195.28Linguistics and Applied Language StudiesIn popular Aotearoa New Zealand media, the public use of te reo Māori in Anglophone-normative spaces – especially for New Zealanders who do not whakapapa Māori (have Māori ancestry) – is commonly reviled as being tokenistic (e.g., Mika, 2022), and psycholinguistic studies have revealed that non-Māori adult learners of the language express anxiety as to whether their attempts to employ it in quotidian situations will be interpreted as tokenistic, performative virtue signaling (e.g., Te Huia, 2020). In this talk, I shall present my analysis of sociolinguistic interview data from various non-Māori learner-speakers of te reo Māori and demonstrate a) how participants interactionally construct, define, and evaluate their own notions of "tokenistic" reo Māori usage; b) how such learner-speakers position themselves as actual speakers of the language and non-Indigenous allies of te ao Māori (Māori worldview and epistemologies); c) construct tokenism along what I term a "cline of authenticity;" and d) that such speakers employ Discourses of racism and colonisation in their critiques against those who oppose the expansion of te reo Māori into broader public domains. My work is rooted theoretically in the tradition of interactional sociolinguistics (Gumperz, 1982; Gumperz, 2015; Tannen, 2005), socio-cutural constructivist approaches to identity via language use (Bucholtz & Hall, 2005), and translanguaging as a decolonial praxis for Indigenous language revitalisation (Cenoz & Gorter, 2017; Seals, 2020; Phyak, 2022; Seals et al., forthcoming). https://cassyni-user-files-prod.s3.amazonaws.com/7nFKDxjgQKxrPAbvc9kn9c https://cassyni.com/slides/outline/TtVbMSduUYJhfvcMkLbriq https://cassyni.com/events/TtVbMSduUYJhfvcMkLbriq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6HZuDZYnckzXKce2sPdE8v https://cassyni.com/events/TtVbMSduUYJhfvcMkLbriq?videoPreview=1 Growing food in cities: challenges and opportunitiesnohttps://cassyni.com/events/TtVbMSduUYJhfvcMkLbriq?videoPreview=12024-08-13T12:00:00+00:001545.52The New Phytologist FoundationUrban horticulture (UH) is increasingly recognised for its potential to sustainably increase local food security and support the delivery important environmental and socio-cultural benefits. However, unlike conventional horticultural production, UH production is small-scale and is managed by individual growers. This variation in management may impact the sustainability of growing and crop productivity. In addition, urban soils can be contaminated with high levels of heavy metals which could pose a risk to human health. Here, we use a combination of citizen science, crop and soil analysis and GIS in UH systems at a UK scale to quantify national food production, explore the potential risks of growing fruits and vegetables in cities and how growing practices at a small-scale impacts on crop nutrient concentrations. Our research demonstrates that UH currently makes a small, but important contribution to local food security with potential to greatly expand production in existing greenspaces without risk to human health from soil contamination. https://cassyni-user-files-prod.s3.amazonaws.com/6HZuDZYnckzXKce2sPdE8v https://cassyni.com/slides/outline/79GDQjTs3K3SXwA5UDgWqK https://cassyni.com/events/79GDQjTs3K3SXwA5UDgWqK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UZTeaTfUbD9hSU7GHYiyH8 https://cassyni.com/events/79GDQjTs3K3SXwA5UDgWqK?videoPreview=1 Advances in Advancing Interfaces: The Mathematics of Manufacturing of Industrial Foams, Fluidic Devices, and Automobile Paintingnohttps://cassyni.com/events/79GDQjTs3K3SXwA5UDgWqK?videoPreview=12025-02-28T20:00:00+00:002830.0AI Institute in Dynamic SystemsComplex dynamics underlying industrial manufacturing depend in part on multiphase multiphysics, in which fluids and materials interact across orders of magnitude variations in time and space. In this talk, we will discuss the development and application of a host of numerical methods for these problems, including Level Set Methods, Voronoi Implicit Interface Methods, implicit adaptive representations, and multiphase discontinuous Galerkin Methods. Applications for industrial problems will include modeling how foams evolve, how electro-fluid jetting devices work, and the physics and dynamics of rotary bell spray painting across the automotive industry.https://cassyni-user-files-prod.s3.amazonaws.com/UZTeaTfUbD9hSU7GHYiyH8 https://cassyni.com/events/JzrLdmWLyfGFde8jdKFG2R/abstract https://cassyni-user-files-prod.s3.amazonaws.com/39tiFq86VEDT9WHUrvcoXt https://cassyni.com/slides/outline/4BQDFG6bovedKhr2cfRXUh https://cassyni.com/events/4BQDFG6bovedKhr2cfRXUh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/W2uepWjmMxNazN8tHNe6t6 https://cassyni.com/events/4BQDFG6bovedKhr2cfRXUh?videoPreview=1 Welcome & Opening Remarksnohttps://cassyni.com/events/4BQDFG6bovedKhr2cfRXUh?videoPreview=12025-01-14T11:00:00+00:00224.04Academic Publishing in EuropeNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/W2uepWjmMxNazN8tHNe6t6 https://cassyni.com/slides/outline/H1qajbBxBR9xkDvRLoqC9b https://cassyni.com/events/H1qajbBxBR9xkDvRLoqC9b/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QRet7HoZAAmPUSf68ASR66 https://cassyni.com/events/XqHi86bhM9mJzqdnrrJZ1f/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Bo79ZrRfcVTevVdiWDgHmp https://cassyni.com/events/F3fWGJL9Tzq6qyg4ECfDRX/seminar/qa https://cassyni.com/slides/outline/F3fWGJL9Tzq6qyg4ECfDRX https://cassyni.com/events/F3fWGJL9Tzq6qyg4ECfDRX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/SME5RKd9zvvhLRtXYkoMjC https://cassyni.com/events/F3fWGJL9Tzq6qyg4ECfDRX?videoPreview=1 Data Insights to Advance Editorial Board Diversitynohttps://cassyni.com/events/F3fWGJL9Tzq6qyg4ECfDRX?videoPreview=12025-05-15T15:00:00+00:002635.6Topics at the heart of our communitySowmya Swaminathan, Director, DEI, Research will speak about how Springer Nature is taking a data-informed approach to support diversifying editorial boards and gender representation in peer review and its importance in inclusive publishing.https://cassyni-user-files-prod.s3.amazonaws.com/SME5RKd9zvvhLRtXYkoMjC https://cassyni.com/events/5evgfsJt5tQyTywGypPR8h/seminar/qa https://cassyni.com/slides/outline/5evgfsJt5tQyTywGypPR8h https://cassyni.com/events/5evgfsJt5tQyTywGypPR8h/abstract https://cassyni-user-files-prod.s3.amazonaws.com/YJqoVSm8Xn7fiPFys6GHVY https://cassyni.com/events/5evgfsJt5tQyTywGypPR8h?videoPreview=1 Liquid Biopsies in Clinical Oncologynohttps://cassyni.com/events/5evgfsJt5tQyTywGypPR8h?videoPreview=12025-06-11T14:00:00+00:003501.8Research Seminars by Springer NatureThe investigation of liquid biopsies as key tools in the identification of actionable cancer biomarkers and in the clinical management of patients with cancer is an active field of research. Nature Cancer and Nature Biotechnology are organising a webcast on the current trends in applications of liquid biopsies in cancer diagnosis, prognosis and therapy and the features of robust liquid biomarkers.https://cassyni-user-files-prod.s3.amazonaws.com/YJqoVSm8Xn7fiPFys6GHVY https://cassyni.com/events/C5MYGkihnqcfHodjqimpjo/seminar/qa https://cassyni.com/slides/outline/C5MYGkihnqcfHodjqimpjo https://cassyni.com/events/C5MYGkihnqcfHodjqimpjo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5LwF9Lcbhz7zLBAq3WiUNS https://cassyni.com/events/C5MYGkihnqcfHodjqimpjo?videoPreview=1 Nektar++ Updates and Future Developmentsnohttps://cassyni.com/events/C5MYGkihnqcfHodjqimpjo?videoPreview=12025-06-24T12:30:00+00:003342.84Nektar++ Development TeamThis sessions gives updates on progress, highlights new developments, reports on the merge request and provides future perspectiveshttps://cassyni-user-files-prod.s3.amazonaws.com/5LwF9Lcbhz7zLBAq3WiUNS https://cassyni.com/events/NSzrMjpcQpAoxndH9PfA3w/seminar/qa https://cassyni.com/slides/outline/NSzrMjpcQpAoxndH9PfA3w https://cassyni.com/events/NSzrMjpcQpAoxndH9PfA3w/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3LF8ki6qPZvrZGQiR2ei6a https://cassyni.com/events/NSzrMjpcQpAoxndH9PfA3w?videoPreview=1 Solver developmentsnohttps://cassyni.com/events/NSzrMjpcQpAoxndH9PfA3w?videoPreview=12025-06-25T10:00:00+00:006076.88Nektar++ Development TeamAccurate numerical simulations of unsteady fluid flows require high-fidelity methods such as large eddy simulation and direct numerical simulation. Both methods are, however, limited in practical applications due to high computational costs. While the straightforward way to escape this issue is using more computational resources, cost and time constraints often require algorithmic improvements instead. High-fidelity methods typically rely on explicit time-stepping schemes due to low computational cost per time step. In this work, we investigate an implicit time-stepping scheme that increases the computational cost for each time step, but permits larger time steps to reduce the total time-to-solution. In particular, we study a class of fractional step schemes known as velocity correction schemes that are commonly employed for solving the incompressible Navier-Stokes equations. The workhorse semi-implicit velocity correction scheme uses implicit diffusion and explicit advection treatment. The explicit advection treatment becomes a performance bottleneck for high Reynolds number flows around complex geometries, because of a CFL-type condition that constrains the algorithm’s stability. We explore a linear-implicit velocity correction scheme which removes the CFL limitation. The linear-implicit scheme uses a linearisation of the advection operator and, hence, preserves the linear structure of the semi-implicit algorithm. As such the approach efficiently improves stability without significant computational overhead. We perform a comparison of both, the semi-implicit and linear-implicit, velocity correction schemes and look into their stability, accuracy and computational performance. Our investigation includes canonical problems and a low Reynolds number and two-dimensional cylin- der flow for verification. Further, we investigate turbulent flows at high Reynolds number and around challenging geometries based on Formula 1 race cars. We find that the linear-implicit scheme achieves strong improvements in the stability allowing up to 100-times larger time step sizes on the most complex 3D geometry. The influence on the accuracy with larger time step sizes varies and all cases show negligible differences up to at least 10-times larger time step sizes. Additionally, the stability improvement provides leverage for the computational performance enabling a 5-fold speed-up without loss in accuracy and a 10-fold speed-up in time-to-solution with minor losses in the accuracy. Level set equations coupled with Navier-Stokes equations are implemented into the Nektar++ framework to model the interface dynamics and surface tension in order to produce a spectral/hp multiphase solver. This multiphase solver is built on top of the existing Incompressible Navier-Stokes Solver (IncNavierStokesSolver) and handles two fluids (liquid or gas) with different physical properties. The level set field is treated as a smeared out Heaviside function with values in the range of 0 to 1 representing the diffuse interface. Following the explicit advection of the level set function, the reinitialisation of the level set function is achieved through the solution of Helmholtz form of the remaining level set equation with addition of artificial compressive flux and a small viscosity value proportional to the grid resolution. The diffused interface level set field is utilised to model the interface curvature and surface tension as a continum surface force (CSF) accounted for in the momentum conservation. As a first step, the results of the benchmark test cases of advection (rotating circle) and deformation (vortex) as well as Zalesak's slotted disk and 3D sphere deformation from the Continuous Galerkin form of level set function solution, revealed that the spectral/hp framework Nektar++ was able to produce accurate results and limited numerical diffusion even in coarse meshes. The performance of the current version of the solver is presented with sample cases of liquid droplet deformation under uniform gas flow and the effect of surface tension. https://cassyni-user-files-prod.s3.amazonaws.com/3LF8ki6qPZvrZGQiR2ei6a https://cassyni.com/events/RQv6kUDeSvRSsjRuttvrv1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QxUd58dX5Xs2eyN98kvSw8 https://cassyni.com/slides/outline/DZKyXSBAWaCdn2TFjoN7iu https://cassyni.com/events/DZKyXSBAWaCdn2TFjoN7iu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/X5DQ5ixTNjzTbv8wQxX3Sn https://cassyni.com/events/DZKyXSBAWaCdn2TFjoN7iu?videoPreview=1 Generative AI for businessnohttps://cassyni.com/events/DZKyXSBAWaCdn2TFjoN7iu?videoPreview=12023-07-25T23:00:00+00:003095.28Business SchoolGenerative Artificial Intelligence (AI) is a rapidly evolving and critical topic for businesses, transforming knowledge creation and productivity across various sectors. The widespread adoption of AI, particularly generative models like ChatGPT, MidJourney, and Stable Diffusion, is attributed to advancements in computational power, exponential data growth, and sophisticated machine learning algorithms inspired by neural networks. These tools enable the generation of human-like text, images, and music; answer questions; translate languages; and engage in conversation, moving beyond traditional AI applications such as process automation, computer vision, digital humans, and robotics. Key applications in business include automating repeatable processes, such as customer service inquiries and loan applications, and creating novel digital experiences. Specific examples highlight AI's role in endangered species protection (Maui 63's dolphin identification drone), worker safety (Vulcan Steel's hard hat/vest detection), retail innovation (Imager's checkout-free carts), and crime prevention (Aura's bias-free facial recognition, Wi-Fi signal human movement detection). While offering significant productivity gains, AI presents ethical challenges related to data privacy, algorithmic bias, and the potential for deepfake misuse. Companies are encouraged to foster an "AI-first" culture through strategic integration, robust data governance, and ethical guidelines. Future advancements anticipate thought-controlled interfaces for seamless human-machine interaction.https://cassyni-user-files-prod.s3.amazonaws.com/X5DQ5ixTNjzTbv8wQxX3Sn https://cassyni.com/slides/outline/hpieHgLnJmNXWfamDkXfs https://cassyni.com/events/hpieHgLnJmNXWfamDkXfs/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BHSNf6TXndZLvwSrm1pYtW https://cassyni.com/events/hpieHgLnJmNXWfamDkXfs?videoPreview=1 The Validity of Stress Models in Predicting Human Psychopathology: Behavioral and Neurochemical Correlates, and Targets for Pharmacological Evaluationsnohttps://cassyni.com/events/hpieHgLnJmNXWfamDkXfs?videoPreview=12025-03-19T06:00:00+00:005154.72The Pharmacological Research family of journalsThe inadequacy of the germ and terrain theories as the sole determinants of diseases led to the postulation that chronic stress plays a key role in the genesis and progression of many chronic human diseases through induction of a cascade of multi-systemic physiological dysregulations. The pathomechanisms underlying chronic stress-induced diseases include over-production of injurious chemical mediators, depletion of stress-protective molecules and inability to stimulate specific stress-protective pathways resulting from hypothalamic-pituitary-adrenal (HPA) axis activation. Molecular studies have also implicated myriads of epigenetic mechanisms that underlie dysregulation of genes in the neural circuitries in chronic stress-induced disorders. Generally, animal models are used as proxies for humans to elucidate the occurrence and progression of pathological processes, and development of pharmacological agents. Animal models of stress are widely used to investigate the neural, behavioral and biochemical mechanisms involved in chronic stress-induced psychopathology including depression, anxiety, posttraumatic stress disorders, schizophrenia, cognitive deficits, aggressive and addictive disorders. The purpose of the models is to correlate the physiological and behavioral changes associated with specific stressors to the etiology of diseases and responses to pharmacological treatments. Notably, animal stress models have predictive validity, face validity and construct validity attesting to their reliability in studying the pathogenesis of psychiatric disorders and pharmacological interventions. Broadly, they can be classified into predictable stress models and unpredictable chronic mild stress paradigm. Predictable stress models involve exposure of the organisms to a single stressor, which can lead to the development of tolerance, plasticity and adaptation upon repeated exposures. On the other hand, the unpredictable chronic mild stress paradigm that closely mimics how humans encounter different stressors on daily basis entails the exposures of the animals to multiple stressors, in a random manner; and it is now widely recognized as a valuable tool to elucidate the neurobiology of chronic stress-induced psychiatric disorders. This discourse aims to stimulate more robust studies on the neurobiology of chronic stress-induced psychopathologies, highlight some targets for pharmacological interventions, and the possibility of developing animal model(s) for testing social supports benefits in the face of adversity.https://cassyni-user-files-prod.s3.amazonaws.com/BHSNf6TXndZLvwSrm1pYtW https://cassyni.com/slides/outline/Ca2mS4t7df6V7GdFdptnv1 https://cassyni.com/events/Ca2mS4t7df6V7GdFdptnv1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VVPpwTomUboZujWkGWzKWn https://cassyni.com/events/Ca2mS4t7df6V7GdFdptnv1?videoPreview=1 Accelerating digital to build the 'bionic company': Framework and case study datenohttps://cassyni.com/events/Ca2mS4t7df6V7GdFdptnv1?videoPreview=12020-09-22T23:00:00+00:003530.04Business SchoolThe imperative for digital transformation has significantly accelerated, with 80% of companies planning increased investment following the COVID-19 pandemic. This shift is explored through the "Bionic Company" framework developed by Boston Consulting Group (BCG), which uses the Digital Acceleration Index (DAI) to measure digital maturity. The framework integrates technology, such as data and digital platforms, with human elements, including organization, talent, and agile ways of working. This is all centred on a clear strategy and purpose to drive digital outcomes like new offerings and personalized customer experiences. Analysis using the DAI indicates that "Bionic leaders" consistently achieve higher earnings, greater innovation spend, and increased enterprise value. These leaders invest more in digital initiatives, allocate a higher percentage of their workforce to digital roles, and prioritize continuous upskilling. They also focus on end-to-end process digitization and derive a larger share of revenue from digital sources. A case study of a major Western government agency, initially assessed as a "Digital literate" with a DAI score of 33, illustrates this approach. The agency aims to achieve a "Digital leader" status (DAI score of 79) by 2025, prioritizing four key areas: Skills and People, Leadership and Culture, Advanced Analytics and AI, and End-to-end User Journeys. Findings emphasize that successful digital transformation relies heavily on integrated technology-human strategies, strong leadership, and substantial investment in people and culture, which collectively account for 70% of generated value.https://cassyni-user-files-prod.s3.amazonaws.com/VVPpwTomUboZujWkGWzKWn https://cassyni.com/events/Ly5fLKPvVoSCR5g7zFAHmX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3fF6HuSKKMHgsfDbf1CWjG https://cassyni.com/slides/outline/KynTEx6sctL3kKr7tGgxxd https://cassyni.com/events/KynTEx6sctL3kKr7tGgxxd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CCGMzPSFaABkbtU9gSx9oC https://cassyni.com/events/KynTEx6sctL3kKr7tGgxxd?videoPreview=1 Photon localisation and Bloch symmetry breaking in luminal gratingsnohttps://cassyni.com/events/KynTEx6sctL3kKr7tGgxxd?videoPreview=12025-06-17T05:00:00+00:001719.76ETOPIMIn gratings synthetically moving at nearly the velocity of light a symmetry breaking transition is observed between free-flowing fluid-like Bloch waves observed at lower grating velocities and, at luminal velocities, condensed, localised states of light captured in each period of the grating and locked to its velocity. We introduce a new technique for calculating in this regime and use it to study the transition in detail shedding light on the critical exponents, and the periodic oscillations in transmitted intensity seen in the pre-transition regime [1].https://cassyni-user-files-prod.s3.amazonaws.com/CCGMzPSFaABkbtU9gSx9oC https://cassyni.com/slides/outline/WMQ9DJgtqVxUGq9FuNdre9 https://cassyni.com/events/WMQ9DJgtqVxUGq9FuNdre9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2fvEFJ2Mohn2buP7GuWWNa https://cassyni.com/events/WMQ9DJgtqVxUGq9FuNdre9?videoPreview=1 How to make a matte surface broadband transparent?nohttps://cassyni.com/events/WMQ9DJgtqVxUGq9FuNdre9?videoPreview=12025-06-18T03:00:00+00:001930.24ETOPIMThe long-standing paradox between matte appearance and transparency has deprived traditional matte materials of optical transparency. Here, we present a solution to this centuries-old optical conundrum by harnessing the potential of disordered optical metasurfaces. By constructing a random array of meta-atoms tailored in asymmetric backgrounds, we have created transparent matte surfaces that maintain clear transparency regardless of the strength of disordered light scattering or their matte appearances. This remarkable property originates in achieving highly asymmetric light diffusion, exhibiting substantial diffusion in reflection and negligible diffusion in transmission across the visible spectrum. By fabricating macroscopic samples of such metasurfaces through industrial lithography, we have experimentally demonstrated transparent windows camouflaged as traditional matte materials and transparent displays with high clarity, full color, and one-way visibility. This discovery introduces an unprecedented frontier of transparent matte materials in optics, offering unprecedented opportunities and applications.https://cassyni-user-files-prod.s3.amazonaws.com/2fvEFJ2Mohn2buP7GuWWNa https://cassyni.com/events/C4Hsvq92V8R3hEVjHSENvq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JvpY6r1TUajoosBrgEWybL https://cassyni.com/slides/outline/Wr3kFzLRGxWXGbg9VoveuT https://cassyni.com/events/Wr3kFzLRGxWXGbg9VoveuT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5PV4145kDipX87k1AG7g62 https://cassyni.com/events/Wr3kFzLRGxWXGbg9VoveuT?videoPreview=1 Coherent control of wave scattering via engineering of spectral singularitiesnohttps://cassyni.com/events/Wr3kFzLRGxWXGbg9VoveuT?videoPreview=12025-06-19T01:00:00+00:002277.88ETOPIMControlling multiple scattering of waves in higher dimensional geometries has been an area where analytic methods and mathematical insight has been lacking and black-box optimization is considered the only viable approach. However, the theory of Coherent Perfect Absorption 1 (CPA) and Reflec,onless Scattering Modes 2 (RSM) has shown that there exist discrete solutions to scattering of linear waves, even in high dimensional multiple-scattering geometries, that achieve important control functions: perfect transduction (CPA) and perfect (reflectionless) impedance matching (RSM). Generically, the solu,ons are at complex frequency and are only accessible transiently; but with tuning of two system parameters, they can be realized in steadystate at a given real frequency. Here we show 3 the existence of a wider class of such functionalized scattering solutions in the complex plane, including transmission zeros, which can be tuned to become steady-state solutions in the same manner. We refer to such solutions as critically constrained scattering modes (CCONs), as they have boundary conditions which lead to discrete complex spectra. We show theoretically 3 that with more tuning parameters, more highly constrained control func,ons can be achieved, such as routing or demultiplexing, using CCONs as building blocks. Mathematically these functions are equivalent to creating a d-fold coincidence of complex eigenvalues at the same real frequency; we find that 2d tuning parameters are needed to achieve routing between ports; for example, routing a signal without any reflection between three ports requires four tuning parameters. For heuristic reasons we expect an open low-loss wave-chaotic cavity with tunable scattering elements to be optimal for achieving such routing functions, since such a cavity has overlapping, pseudo-random resonances, making it frequency agnostic, and easily reprogrammable. We will present the results of recent experiments 4 and simulations 3,4 of such a cavity that have confirmed this conjecture in the microwave frequency range. Thus, these discrete spectra provide a new framework for understanding the extent to which reverberation and interference can be harnessed for control func,ons based on a definite number of control knobs. Since these systems are easily reprogrammable and flexible, they are robust to perturbations and to fabrication defects, and they have the potential to be uniquely effective for applications where frequency-agile performance is required.https://cassyni-user-files-prod.s3.amazonaws.com/5PV4145kDipX87k1AG7g62 https://cassyni.com/events/QuBDFEUZJPk1ThJPYWGSvq/seminar/qa https://cassyni.com/slides/outline/QuBDFEUZJPk1ThJPYWGSvq https://cassyni.com/events/QuBDFEUZJPk1ThJPYWGSvq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PA3QJeYqyUHUh4Mmi9bzrJ https://cassyni.com/events/QuBDFEUZJPk1ThJPYWGSvq?videoPreview=1 Addressing Neurodegenerative Diseases in Support of SDG 3: Good Health and Wellbeing: Recent Advances in Alzheimer’s and Other Neurodegeneration Research nohttps://cassyni.com/events/QuBDFEUZJPk1ThJPYWGSvq?videoPreview=12025-10-08T11:30:00+00:005573.92Springer Nature Sustainable Development Goals ProgrammeThis webinar will present some of the recent research, efforts, and initiatives put forward by some of Springer Nature's top journals in a number to publish and promote research on Alzheimer's and Neurodegeneration. These journals are from a variety of disciplines such as genomics, genetics, biophysics, and more. The webinar will be introduced with a special introduction by Alzheimer's Research UK, who will contextualise the upcoming talks from our journal editors and the ongoing fight against these diseases which are major parts of SDG 3: Good Health and Wellbeing. Update: unfortunately Alzheimer's Research UK could not make today's seminar, we'll hope to include them in a future seminar. https://cassyni-user-files-prod.s3.amazonaws.com/PA3QJeYqyUHUh4Mmi9bzrJ https://cassyni.com/events/PRG2Dp3sPP15BkbWwV8ouf/seminar/qa https://cassyni.com/slides/outline/PRG2Dp3sPP15BkbWwV8ouf https://cassyni.com/events/PRG2Dp3sPP15BkbWwV8ouf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3hZoz6Xhd99YNsVKfnN5Cz https://cassyni.com/events/PRG2Dp3sPP15BkbWwV8ouf?videoPreview=1 AI-empowered Structural Health Monitoring for Civil Structuresnohttps://cassyni.com/events/PRG2Dp3sPP15BkbWwV8ouf?videoPreview=12025-11-21T12:00:00+00:005397.28ArtIStE - Artificial Intelligence in Structural EngineeringThis talk introduces AI-driven approaches for enhancing structural health monitoring (SHM) using distributed sensing technologies and high-dimensional data analytics. It will examine how machine learning can improve condition assessment in sparsely instrumented systems and support predictive maintenance strategies. The session concludes with an overview of generative models designed to simulate and guide long-term structural management. https://cassyni-user-files-prod.s3.amazonaws.com/3hZoz6Xhd99YNsVKfnN5Cz https://cassyni.com/slides/outline/68ZsbtQW2McxWsqFP9QSe1 https://cassyni.com/events/68ZsbtQW2McxWsqFP9QSe1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CbTGwRcNgsncSsv9S7PE4n https://cassyni.com/events/68ZsbtQW2McxWsqFP9QSe1?videoPreview=1 The origins and future of the Grand Canyonnohttps://cassyni.com/events/68ZsbtQW2McxWsqFP9QSe1?videoPreview=12022-06-29T06:00:00+00:005327.08Part of the nonprofit Annual Reviews organizationHow old is the Grand Canyon? Will the Colorado River run dry? Learn about how the Big Ditch formed, and the present state and uncertain future of the Colorado River watershed.https://cassyni-user-files-prod.s3.amazonaws.com/CbTGwRcNgsncSsv9S7PE4n https://cassyni.com/events/G1XxXZLzoWhHNPqGtiAomw/seminar/qa https://cassyni.com/slides/outline/G1XxXZLzoWhHNPqGtiAomw https://cassyni.com/events/G1XxXZLzoWhHNPqGtiAomw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/K9MRGLvep1H2VDAWTnNipW https://cassyni.com/events/G1XxXZLzoWhHNPqGtiAomw?videoPreview=1 Some recent progress on modeling and designing stellaratorsnohttps://cassyni.com/events/G1XxXZLzoWhHNPqGtiAomw?videoPreview=12025-10-23T15:00:00+00:003149.92Journal of Plasma PhysicsI will discuss recent work in my research group on the modeling and optimization of 3D toroidal fusion devices (stellarators). We have recently designed a new MHD equilibrium solver that can: produce robust 3D equilibrium solutions with islands and chaos by using magnetic relaxation, scale on modern GPUs and provide differentiable objectives by using JAX, and use nonuniform meshes and numerically conserve the relevant structural properties to machine precision by using mixed FE. Moreover, a long-standing issue for stellarators has been finding suitable coils. Traditional optimization methods struggle to balance multiple physics and engineering constraints, often finding suboptimal or infeasible configurations. We present a new optimization method based on an augmented Lagrangian scheme that yields improved stellarator coils that exhibit enhanced physics performance and meet essential design requirements, therefore making progress towards commercially viable stellarator fusion reactors.https://cassyni-user-files-prod.s3.amazonaws.com/K9MRGLvep1H2VDAWTnNipW https://cassyni.com/events/MShE9hyf2uiQeH7UBuM9Mw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5EZ7A5fpRvXswNyq66wDJv https://cassyni.com/slides/outline/E42poNrTkkcERBuPjaKFp1 https://cassyni.com/events/E42poNrTkkcERBuPjaKFp1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/1vfwaK5aACr1zvzJELijp https://cassyni.com/events/E42poNrTkkcERBuPjaKFp1?videoPreview=1 Frontiers of funding: Evidence, experiments, and reforming assessmentnohttps://cassyni.com/events/E42poNrTkkcERBuPjaKFp1?videoPreview=12025-06-30T08:00:00+00:005461.36This seminar addresses contemporary challenges and innovations in research funding, emphasizing the integration of evidence and experimentation to reform assessment practices. Funders from diverse institutions—including the Wellcome Trust, Volkswagen Foundation, Open Philanthropy, and others—are actively exploring novel funding mechanisms and data-driven approaches to enhance equity, transparency, and impact in science. Key initiatives include Wellcome’s equity framework targeting underrepresented groups and global research centers, and its adoption of partial randomization in funding decisions to mitigate biases such as the Matthew effect. The foundation’s commitment to open metadata and the Barcelona Declaration aims to improve research transparency and facilitate metascientific analysis. Open Philanthropy’s development of a “pop-up journal” exemplifies efforts to coordinate research around socially relevant questions, promoting replication and synthesis to inform policy. The Volkswagen Foundation’s experimentation with distributed peer review illustrates attempts to democratize and diversify grant evaluation while maintaining rigor. Across these efforts, collaboration among funders and researchers is highlighted as essential for building a collective evidence base to guide reforms. The seminar underscores the intertwined goals of equity, evidence, and engagement to sustain research excellence amid evolving scientific, societal, and geopolitical landscapes. It advocates for metascience as a critical tool to enhance trustworthiness, inclusivity, and adaptability in research ecosystems, ultimately supporting science as a global public good.https://cassyni-user-files-prod.s3.amazonaws.com/1vfwaK5aACr1zvzJELijp https://cassyni.com/events/RtZHgVKGPPdRvdKtJDwtRK/seminar/qa https://cassyni.com/slides/outline/RtZHgVKGPPdRvdKtJDwtRK https://cassyni.com/events/RtZHgVKGPPdRvdKtJDwtRK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2q7xVy8rPvcxsuBQgSD2XY https://cassyni.com/events/RtZHgVKGPPdRvdKtJDwtRK?videoPreview=1 The Cahn–Hilliard–Navier–Stokes framework for multiphase fluid flows: laminar, turbulent and activenohttps://cassyni.com/events/RtZHgVKGPPdRvdKtJDwtRK?videoPreview=12026-02-05T16:00:00+00:003019.48Journal of Fluid MechanicsThe Cahn–Hilliard–Navier–Stokes (CHNS) partial differential equations (PDEs) provide a powerful framework for the study of the statistical mechanics and fluid dynamics of multiphase fluids. We provide an introduction to the equilibrium and non-equilibrium statistical mechanics of systems in which coexisting phases, distinguished from each other by scalar order parameters, are separated by an interface. We then introduce the coupled CHNS PDEs for two immiscible fluids and generalisations for (i) coexisting phases with different viscosities, (ii) CHNS with gravity, (iii) three-component fluids and (iv) the CHNS for active fluids. We discuss mathematical issues of the regularity of solutions of the CHNS PDEs. Finally we provide a survey of the rich variety of results that have been obtained by numerical studies of CHNS-type PDEs for diverse systems, including bubbles in turbulent flows, antibubbles, droplet and liquid-lens mergers, turbulence in the active-CHNS model and its generalisation that can lead to a self-propelled droplet.https://cassyni-user-files-prod.s3.amazonaws.com/2q7xVy8rPvcxsuBQgSD2XY https://cassyni.com/events/UMoJuuYtagPvHZoSqurX9F/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2YojMxDpcTibMVzDYLuBPC https://cassyni.com/events/Bmyt8GWCotwWDseGamFjs/seminar/qa https://cassyni.com/slides/outline/Bmyt8GWCotwWDseGamFjs https://cassyni.com/events/Bmyt8GWCotwWDseGamFjs/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JRTuMrs4oVqM7KjRcs9bRg https://cassyni.com/events/Bmyt8GWCotwWDseGamFjs?videoPreview=1 Microporous Materials with Tailored Structural Properties for Enhanced Gas Separationnohttps://cassyni.com/events/Bmyt8GWCotwWDseGamFjs?videoPreview=12026-04-29T10:00:00+00:003149.52ElsevierExtensive research on gas separation has been performed, as industrial separation processes, namely cryogenic distillation and liquefaction, are considerably energy-intensive. In this regard, adsorbents and membranes that demonstrate favorable interaction with the desired greenhouse gases (i.e., carbon dioxide (CO2) and sulfur hexafluoride (SF6)) are selected due to their capability in performing effective separation at a lower energy penalty and a smaller plant footprint. Thus, this presentation shares several research works on novel nanoporous materials and membranes towards effective separation and capture of greenhouse gases. First, for the case of nanoporous materials, various material categories (zeolites, metal-organic frameworks, porous polymers, and porous carbons) are investigated for greenhouse gas adsorption. In general, adsorbents with hierarchical structures improve the adsorption kinetics of greenhouse gases without sacrificing their equilibrium and kinetic gas adsorption performance substantially. On the other hand, porous materials are utilized as fillers in mixed-matrix membranes (MMM) to improve the undesirable permeability-selectivity trade-off in polymeric membranes. This can be investigated by utilizing fillers with various functionalities to tune the overall CO2-based separation performance. This behavior will potentially translate towards enhanced CO2 permeability as well as CO2/N2 (or CO2/CH4) selectivity.https://cassyni-user-files-prod.s3.amazonaws.com/JRTuMrs4oVqM7KjRcs9bRg https://cassyni.com/events/G1E7GdgFNYWHkqb1ndEcbw/seminar/qa https://cassyni.com/slides/outline/G1E7GdgFNYWHkqb1ndEcbw https://cassyni.com/events/G1E7GdgFNYWHkqb1ndEcbw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/63BmgmKoC9RBc3zSBKWb6E https://cassyni.com/events/G1E7GdgFNYWHkqb1ndEcbw?videoPreview=1 Adaptive management approach – Kansas City success storynohttps://cassyni.com/events/G1E7GdgFNYWHkqb1ndEcbw?videoPreview=12026-03-31T14:00:00+00:001921.8Cambridge PrismsThe Kansas City, Missouri Smart Sewer Program has successfully implemented an adaptive management approach to cost-effectively reduce sewer overflows. This approach was implemented under the guidance of the third Consent Decree modification, which mandates the level of sewer overflow reduction. This approach includes iterative decision-making, continuous monitoring and flexible strategies to optimize environmental outcomes while managing costs. The adaptive management framework integrates system performance and past project data into an iterative planning, implementation, monitoring and analysis cycle. This process enables cost-effective decision-making aligned with Consent Decree compliance by managing the uncertainties in sewer system data and the interdependency of proposed project outcomes. The Smart Sewer Program adopted this approach in response to financial challenges and environmental requirements, resulting in key modifications to its original Overflow Control Plan projects. The adaptive management approach, enabled by the third Consent Decree modification, has proven pivotal in optimizing project performance, reducing costs and protecting vulnerable populations. By leveraging the adaptive management approach, Kansas City has reduced program expenses by hundreds of millions of dollars while aligning with Environmental Protection Agency (n.d.) environmental justice goals. Key project modification examples from the program presented in this article illustrate the effectiveness of adaptive management in achieving better outcomes. The first example showcases a project substitution. In this example, green infrastructure replaced a proposed relief sewer project, resulting in a more cost-effective solution with enhanced overflow reduction and environmental justice benefits. The second example involves project augmentation with creek separation, resolving double-counted sewer overflows, and significantly reducing annual overflow volume at minimal cost. A third example demonstrates project modification for a City project that was not a part of the Smart Sewer Program, where alternative gate configurations increased overflow capture without additional costs, potentially eliminating the need for a costly deep tunnel project. This article demonstrates the potential of an adaptive management approach for urban wastewater management programs, offering a replicable model for other municipalities. The Kansas City Smart Sewer Program example demonstrates how adaptive management can drive cost savings, enhance environmental outcomes and ensure regulatory compliance for a Consent Decree.https://cassyni-user-files-prod.s3.amazonaws.com/63BmgmKoC9RBc3zSBKWb6E https://cassyni.com/events/GVuLRwqfDMz7aJaXajMan9/seminar/qa https://cassyni.com/slides/outline/GVuLRwqfDMz7aJaXajMan9 https://cassyni.com/events/GVuLRwqfDMz7aJaXajMan9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4Sx6S17aA8gPg5wbJCdQJS https://cassyni.com/events/GVuLRwqfDMz7aJaXajMan9?videoPreview=1 Emerging Directions for Space-Time Metamaterialsnohttps://cassyni.com/events/GVuLRwqfDMz7aJaXajMan9?videoPreview=12026-06-02T13:00:00+00:003328.28MetaMATMost signals encountered in optics, communications, sensing, and computing vary in both space and time, yet many optical systems process them using static structures that treat time only as a passive parameter. This talk will discuss why the full use of structured light requires materials whose properties can vary in both space and time. I will present emerging directions in space-time metamaterials, showing how space-time modulation can overcome fundamental limits, enable practical optical isolators, and provide new tools for controlling wavepackets with coupled spatial and temporal structure. I will also discuss how these ideas can support future platforms for information processing and optical computing.https://cassyni-user-files-prod.s3.amazonaws.com/4Sx6S17aA8gPg5wbJCdQJS https://cassyni.com/events/RtFSRZeWxRSSK55dC91hFK/seminar/qa https://cassyni.com/slides/outline/RtFSRZeWxRSSK55dC91hFK https://cassyni.com/events/RtFSRZeWxRSSK55dC91hFK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/H2exdjVE2ayLNv9e57F98 https://cassyni.com/events/RtFSRZeWxRSSK55dC91hFK?videoPreview=1 Rethinking Color Perception: Beyond Classical Colorimetry through Quantum Informationnohttps://cassyni.com/events/RtFSRZeWxRSSK55dC91hFK?videoPreview=12026-05-14T13:00:00+00:004381.68Journal on Image and Video ProcessingIn this webinar, I will introduce the basic concepts of a novel theory of color perception grounded in quantum information theory, developed since 2018 by Michel Berthier, Edoardo Provenzi, and collaborators. By reinterpreting the foundational works of Erwin Schrödinger and Howard L. Resnikoff from a quantum information perspective, this framework naturally reconciles trichromacy with Hering’s opponency theory, and provides precise definitions of key color attributes such as brightness, saturation, and hue. Moreover, the theory has genuine predictive power: it allows for a quantitative explanation of known perceptual phenomena and leads to new predictions, including the existence of uncertainty relations for chromatic opponency. Finally, the model directly yields an efficient white balance algorithm.https://cassyni-user-files-prod.s3.amazonaws.com/H2exdjVE2ayLNv9e57F98 https://cassyni.com/events/49irPVBReH52WKoLp3d2Yu/seminar/qa https://cassyni.com/slides/outline/49irPVBReH52WKoLp3d2Yu https://cassyni.com/events/49irPVBReH52WKoLp3d2Yu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/57LKaYsUJQdkcqAB4yv8qU https://cassyni.com/events/49irPVBReH52WKoLp3d2Yu?videoPreview=1 Targeting cell-free DNA for prevention, early diagnosis and treatment of rheumatoid arthritisnohttps://cassyni.com/events/49irPVBReH52WKoLp3d2Yu?videoPreview=12026-06-16T11:00:00+00:004923.44The Pharmacological Research family of journalsCell-free DNA (cf-DNA) is extracellular DNA released during cell death and accumulates in concentration with age. Elevated levels of cf-DNA have been detected in the plasma and disease-affected tissues or organs of patients suffering from various diseases, particularly age-related autoimmune diseases such as rheumatoid arthritis (RA). Recent studies have established cf-DNA as a biomarker for a spectrum of age-related and autoimmune disorders, including cancer, systemic lupus erythematosus (SLE), and psoriasis. Variations in the levels and properties of cf-DNA are indicative of the progression, severity, and prognosis of these conditions. Emerging hypotheses suggest that cf-DNA may mediate one of the pathological pathways in RA, positioning it as a potential target for the development of innovative therapeutic, preventive, and diagnostic strategies. This talk provides a concise overview of the role of age-related cf-DNA in RA, drawing on the latest evidence, and discusses the contemporary therapeutic interventions, prevention techniques, and diagnostic tools that utilize cf-DNA in the management of RA.https://cassyni-user-files-prod.s3.amazonaws.com/57LKaYsUJQdkcqAB4yv8qU https://cassyni.com/slides/outline/D3b62CS5N3XCMzKjPQhhjj https://cassyni.com/events/D3b62CS5N3XCMzKjPQhhjj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LBXgMMvXmvMGz8t2ypTJ7Y https://cassyni.com/events/D3b62CS5N3XCMzKjPQhhjj?videoPreview=1 Metasciences: threading the past and imagining an interwoven futurenohttps://cassyni.com/events/D3b62CS5N3XCMzKjPQhhjj?videoPreview=12024-05-28T08:00:00+00:002543.2 School of Public PolicyThis seminar explores the interrelations and distinctions among key meta-sciences—philosophy, history, sociology, economics, and the science of science—highlighting their shared foundational questions and unique methodological contributions. Emphasizing epistemology as a central thread, the analysis situates knowledge demarcation, justification, and explanation as pivotal across these fields, while tracing their historical development from classical philosophy through to contemporary scientometrics. The discussion underscores the evolving role of scientific documentation and metadata in defining science, the social responsibilities of scientists, and the institutionalization of scientific knowledge. It critically examines cumulative advantage phenomena such as the Matthew effect and the implications of skewed resource and recognition distributions for equity and justice in science. The economics of science is contextualized through the lens of public funding, intellectual property tensions, and innovation dynamics, while the science of science is framed as an empirical, methodological endeavor seeking universal principles governing scientific activity. The seminar advocates for triangulation across meta-scientific theories, methods, and data to address complex questions, cautioning against epistemic hierarchies that privilege certain approaches over others. It highlights the potential of enriched bibliometric metadata and full-text analysis to illuminate disparities, interdisciplinarity, and knowledge flows, stressing the necessity of collective infrastructure for data curation and accessibility to democratize science studies globally. Ultimately, it calls for a shared research agenda that aligns data development with core meta-scientific questions to foster responsible, inclusive, and integrative understanding of science’s past, present, and future.https://cassyni-user-files-prod.s3.amazonaws.com/LBXgMMvXmvMGz8t2ypTJ7Y https://cassyni.com/slides/outline/HVT9YymgiXSAy7mvadQiWq https://cassyni.com/events/HVT9YymgiXSAy7mvadQiWq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5Mn1ikASqSrPC1MECZKK1g https://cassyni.com/events/HVT9YymgiXSAy7mvadQiWq?videoPreview=1 Information Policy and Management: L1 Goals, Uncertainty and Informationnohttps://cassyni.com/events/HVT9YymgiXSAy7mvadQiWq?videoPreview=12019-07-26T08:00:00+00:00661.08 School of Public PolicyThis analysis explores the relationship between organizational goals, arising uncertainties, and the mobilization of information to manage these uncertainties within strategic contexts. Organizations pursue future-oriented goals, which inherently generate uncertainties related to various factors such as resource availability, production processes, market conditions, and social dynamics. These uncertainties represent knowledge gaps that must be addressed through the acquisition and processing of relevant information. Different types of uncertainties—ranging from natural phenomena to social behaviors—necessitate distinct organizational responses, often manifesting as specialized units or devices designed to gather and interpret specific information. The study emphasizes that rational organizational action involves coherent use of available means to achieve stated goals; however, limitations arise due to incomplete, complex, or biased information, which can impede effective decision-making. Information is characterized as temporally and contextually bound “news” that evolves as decisions are made and uncertainties shift, with residual unresolved uncertainties constituting organizational risk. Key properties of information—such as relevance in time and location, level of analysis, detail, source trustworthiness, and required expertise—critically influence its utility in uncertainty reduction. The findings underscore that organizational structures and processes inherently reflect the nature of uncertainties faced and the informational demands necessary for goal attainment, highlighting the central role of information policy and management in strategic organizational behavior.https://cassyni-user-files-prod.s3.amazonaws.com/5Mn1ikASqSrPC1MECZKK1g https://cassyni.com/slides/outline/VqfFi4wogyH2ro1jYyySey https://cassyni.com/events/VqfFi4wogyH2ro1jYyySey/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Pt4YqkQjtkgNRiaoBnvWn2 https://cassyni.com/events/A5ZMAwyViVa2HCR7nHRPpZ/seminar/qa https://cassyni.com/slides/outline/A5ZMAwyViVa2HCR7nHRPpZ https://cassyni.com/events/A5ZMAwyViVa2HCR7nHRPpZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7vtSNJF9RxP93B1g8Go8e2 https://cassyni.com/events/A5ZMAwyViVa2HCR7nHRPpZ?videoPreview=1 On Probability Estimation for Unbalanced Classificationnohttps://cassyni.com/events/A5ZMAwyViVa2HCR7nHRPpZ?videoPreview=12026-07-28T15:00:00+00:003490.32Journal of Statistical Theory and PracticeUnbalanced classification poses a significant challenge in real-world applications such as medical diagnosis and fraud detection, where class label distributions are highly skewed. Standard classification methods on such data can lead to poor classification results, sacrificing classification accuracy on minority classes. Standard classification methods often yield suboptimal results by sacrificing minority class accuracy to maximize overall performance. Common techniques to address unbalanced classification typically involve weighting adjustments of points for different classes or resampling strategies, including oversampling of minority classes and undersampling of majority classes. While these balancing techniques are effective in improving classification accuracy, they often introduce biases that compromise posterior class probability estimation and model calibration. This paper highlights the trade-offs associated with balancing techniques when applied without appropriate adjustments. We systematically investigate the distortions in probability estimation caused by these unbalanced classification techniques and propose a robust framework to correct these biases through probability adjustment. We further investigate high-dimensional unbalanced data, examining both the distortion induced by balancing techniques and the shrinkage effect of regularization on probability estimation. Finally, our method is evaluated through simulations and real data analysis. Finally, our method is evaluated through simulations and real data analysis, covering a range of balancing strategies including class weighting, random resampling, and generative models. Results demonstrate that our proposed framework significantly mitigates probability estimation bias while preserving classification power when applying traditional balancing techniques, ensuring reliable posterior estimates.https://cassyni-user-files-prod.s3.amazonaws.com/7vtSNJF9RxP93B1g8Go8e2 https://cassyni.com/events/CYoNQND7unLWe8tgKyL2YV/seminar/qa https://cassyni.com/slides/outline/CYoNQND7unLWe8tgKyL2YV https://cassyni.com/events/CYoNQND7unLWe8tgKyL2YV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/MAQXFzc52XaVsqPVtQMmm8 https://cassyni.com/events/CYoNQND7unLWe8tgKyL2YV?videoPreview=1 From Evidence to Clinical Recommendations: Methodological Changes in the AGNP TDM Consensus Guidelines 2026nohttps://cassyni.com/events/CYoNQND7unLWe8tgKyL2YV?videoPreview=12026-09-07T08:30:00+00:005089.84Thieme BioSciencesTherapeutic drug monitoring (TDM) is an established tool for optimizing pharmacotherapy through the measurement and interpretation of drug concentrations in blood. Since 2004, the AGNP TDM consensus guidelines have provided international recommendations for best-practice TDM in psychiatry and neurology. The 2026 edition introduces a comprehensive methodological revision. Transparent, systematic approaches were developed to derive both therapeutic reference ranges (TRRs) and dose-related reference ranges (DRRs), integrating evidence from meta-analyses, concentration–response studies, population pharmacokinetic data, and expected concentrations under recommended dosing. These revised methods were applied consistently across all substances, resulting in updated recommendations for 160 neuropsychiatric drugs, including 30 newly evaluated drugs and revisions for 88 existing recommendations. This presentation provides an overview of the methodological framework underlying the 2026 AGNP consensus update, illustrated by selected examples.https://cassyni-user-files-prod.s3.amazonaws.com/MAQXFzc52XaVsqPVtQMmm8 https://cassyni.com/events/B4tBNwnRzmbu6RwXApqAG5/seminar/qa https://cassyni.com/slides/outline/B4tBNwnRzmbu6RwXApqAG5 https://cassyni.com/events/B4tBNwnRzmbu6RwXApqAG5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UgKANmanPm89DGigycmJ54 https://cassyni.com/events/B4tBNwnRzmbu6RwXApqAG5?videoPreview=1 HOW TO GET PUBLISHED IN THE MODERN AGE — An editorial view from Scientific Reports nohttps://cassyni.com/events/B4tBNwnRzmbu6RwXApqAG5?videoPreview=12026-08-12T07:00:00+00:003103.24**本次报告将聚焦学术论文写作的核心技巧与常见误区，会系统解析从投稿到发表的完整出版流程。报告语言为普通话。** This interactive workshop provides researchers with an insider's perspective on academic publishing at Nature Portfolio. Drawing on extensive experience as a full-time scientific editor at *Scientific Reports*, the presentation will focus on the art and strategy of manuscript writing: how to structure a compelling narrative, present data clearly, craft effective abstracts and cover letters, and highlight significance without overclaiming. We will also walk participants through the editorial lifecycle, from submission to decision. Designed for researchers at all career stages, this session aims to build confidence and competence in navigating the publishing landscape. Image credit: [Nick Morrison (Unsplash)](https://unsplash.com/photos/macbook-pro-near-white-open-book-FHnnjk1Yj7Y).https://cassyni-user-files-prod.s3.amazonaws.com/UgKANmanPm89DGigycmJ54 https://cassyni.com/slides/outline/YJuGwVBRtG3XDjVJ6ft5Nu https://cassyni.com/events/YJuGwVBRtG3XDjVJ6ft5Nu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9rmK1YGnFtLxnQNLmXWXKk https://cassyni.com/events/YJuGwVBRtG3XDjVJ6ft5Nu?videoPreview=1 FTC Hearing 4: Emerging Trends in Patent Qualitynohttps://cassyni.com/events/YJuGwVBRtG3XDjVJ6ft5Nu?videoPreview=12018-10-23T08:00:00+00:006359.04 School of Public PolicyThis seminar addresses emerging trends in patent quality within the U.S. intellectual property system, focusing on the role of patents in promoting innovation and the government’s involvement in supporting it. The discussion highlights the U.S. Patent and Trademark Office’s (USPTO) efforts to enhance patent quality through clearer examination policies, improved prior art search capabilities, and increased transparency in post-grant proceedings, particularly via the Patent Trial and Appeal Board (PTAB). Empirical analyses emphasize the dynamic nature of patent quality, shaped by statutory terms, claim scope, enforceability, and clarity of disclosure. The American Invents Act (AIA) and subsequent judicial decisions have introduced expanded post-grant review mechanisms, shifting from static to evolving patent quality by enabling administrative correction of issued patents in response to changing technological and market conditions. Panelists underscore the importance of balancing incentives for examiners and applicants, with fee structures and time allocations influencing claim breadth and examination rigor. The PTAB’s role as a specialized tribunal is noted for its expertise, adversarial procedures, and threshold screening, which contribute to more effective error correction compared to prior reexamination and district court litigation. Challenges remain regarding claim construction standards, procedural consistency, and the integration of artificial intelligence to assist examiners without reducing examination time. The seminar concludes that ongoing empirical research, institutional collaboration, and iterative reforms are essential to fostering a patent system that delivers strong, reliable, and predictable rights, thereby advancing innovation and competition.https://cassyni-user-files-prod.s3.amazonaws.com/9rmK1YGnFtLxnQNLmXWXKk https://cassyni.com/slides/outline/LTEHNZbHjq3u6f74NXFAmK https://cassyni.com/events/LTEHNZbHjq3u6f74NXFAmK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HHVsELBD6RwJRERmy45kN2 https://cassyni.com/slides/outline/77iy8787tU6UTFBF4HBZHo https://cassyni.com/events/77iy8787tU6UTFBF4HBZHo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8CcJZZuNgWXCMtpeaSDdSN https://cassyni.com/events/EXvcm4b4KU9i6riuq5HCVT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CoY78LC8XtZcL7wj2TJzKY https://cassyni.com/slides/outline/TNREUeiBVgWVpdmx6CB5em https://cassyni.com/events/TNREUeiBVgWVpdmx6CB5em/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3soaU4hz7iGN2VNXeRBTSW https://cassyni.com/events/TNREUeiBVgWVpdmx6CB5em?videoPreview=1 Self-Driving Cars and Ethics: An Overviewnohttps://cassyni.com/events/TNREUeiBVgWVpdmx6CB5em?videoPreview=12016-12-12T09:00:00+00:003827.72 School of Public PolicyThis seminar provides a comprehensive overview of the ethical challenges associated with the development and deployment of self-driving cars, emphasizing the critical considerations engineers and stakeholders must address as autonomous vehicles become increasingly prevalent. The discussion outlines the potential societal benefits of self-driving cars, such as reducing traffic congestion, lowering accident rates attributed to human error, and improving transportation access for disabled individuals. Key ethical issues highlighted include privacy concerns arising from extensive data collection, the complexity of pedestrian-vehicle interactions, and the implications of varying levels of automation—particularly the distinctions between Level 3 systems, which require human oversight, and Level 4 systems, which operate with minimal or no human intervention. The analysis explores dilemmas such as the "trolley problem," where programming decisions must be made about prioritizing the safety of passengers versus pedestrians, and the challenges of unexpected user behavior and system failures. Employment impacts due to automation and the responsibilities of manufacturers toward displaced workers are also considered. The seminar underscores the limitations of existing ethical codes in fully resolving these multifaceted issues, advocating for ongoing interdisciplinary dialogue involving engineers, policymakers, legal experts, and the public. It further addresses the need for standardization, liability frameworks, and thoughtful design choices that balance safety, autonomy, and user trust. This overview serves as a foundational resource for understanding the ethical landscape shaping the future of autonomous vehicle technology.https://cassyni-user-files-prod.s3.amazonaws.com/3soaU4hz7iGN2VNXeRBTSW https://cassyni.com/slides/outline/878ffzUiNpud43jTAtamxZ https://cassyni.com/events/878ffzUiNpud43jTAtamxZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/N73uyf9YtHxpFJzdvqVhP4 https://cassyni.com/events/878ffzUiNpud43jTAtamxZ?videoPreview=1 Nano-Enabled Drug Delivery: Exploring Cancer Treatment Opportunitiesnohttps://cassyni.com/events/878ffzUiNpud43jTAtamxZ?videoPreview=12014-09-23T08:00:00+00:003014.84 School of Public PolicyWe compile large sets of nano-related article and patent abstracts. We then analyze these records to learn about changing research emphases to try to project likely future developmental pathways. In this seminar we will focus on Nano-Enabled Drug Delivery (NEDD), considering key emerging topics over time. We will then focus on NEDD being used to treat cancers. We key on 3 dimensions: 1) Which nano components are being researched, 2) To facilitate delivery of which agents (drugs), 3) To treat which cancers. A key aim is to identify R&D opportunities that have not been well-explored yet.https://cassyni-user-files-prod.s3.amazonaws.com/N73uyf9YtHxpFJzdvqVhP4 https://cassyni.com/slides/outline/DYGKBWbVCs12BTKFBWpfuw https://cassyni.com/events/DYGKBWbVCs12BTKFBWpfuw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PdKTBDuK9vyfyxcSi7QZWv https://cassyni.com/events/DYGKBWbVCs12BTKFBWpfuw?videoPreview=1 Dynamic and transport properties in warm dense matternohttps://cassyni.com/events/DYGKBWbVCs12BTKFBWpfuw?videoPreview=12024-01-18T06:00:00+00:002980.64Journal of Plasma PhysicsThe concept of warm dense matter (WDM) emerged over two decades ago, delineating a state of matter existing under extreme conditions—typically at pressures exceeding 100 GPa and concurrently at temperatures ranging between 104–106 K. WDM lies at the intersection of solids and plasmas, and displays a hybrid set of characteristics from both states. In this unique region of phase space, matter attains a state of partial degeneracy and ionization, fostering intricate correlations among charged particles that also exhibit considerable quantum mechanical behaviors. Its intricate nature challenges conventional perturbative techniques, resulting in considerable disparities between theoretical predictions and computational models. In particular, ion transport properties, which play a crucial important for planetary physics, show some of the largest variation with few experimental results. Scattering experiments, utilizing high-intensity beams of penetrating radiation to probe micro-structure and dynamics, represent a pivotal tool for investigating particle dynamics in this regime. Our team recently showcased a groundbreaking inelastic X-ray scattering (IXS) technique for use at X-ray free electron lasers, offering energy resolutions down to 50 meV. This high-resolution technique enables unprecedented access to ion dynamics in plasmas, where the ions typically exhibit much smaller energy shifts than the electrons. In the collective regime, we have measured acoustic waves in warm dense methane, directly determining the sound speed at planetary interior conditions. In the single-particle regime, we have pioneered a direct measurement of ion temperatures in dense plasmas, unveiling new insights into electron-ion temperature exchange. In this presentation, I will provide an overview of our current understanding of transport and dynamics in WDM, spotlighting recent experimental results and discussing future directions.https://cassyni-user-files-prod.s3.amazonaws.com/PdKTBDuK9vyfyxcSi7QZWv https://cassyni.com/slides/outline/A5j5rj4p8f8P9m1gXrSiP7 https://cassyni.com/events/A5j5rj4p8f8P9m1gXrSiP7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FztUMXK8TCHUY3D2GPtquY https://cassyni.com/events/A5j5rj4p8f8P9m1gXrSiP7?videoPreview=1 Electromagnetic Instabilities in Spherical Tokamaksnohttps://cassyni.com/events/A5j5rj4p8f8P9m1gXrSiP7?videoPreview=12023-11-30T06:00:00+00:002857.48Journal of Plasma PhysicsElectromagnetic microinstabilities are likely to dominate transport in high β next generation spherical tokamaks (STs) such as STEP. While gyrokinetic (GK) simulations have thus far proven to be a very accurate tool in modelling turbulent transport in predominantly electrostatic regimes at low β, obtaining saturated nonlinear simulations of plasmas with unstable kinetic ballooning modes (KBMs) and microtearing modes (MTMs) has proven computationally and conceptually challenging. However, recent investigations that retain only MTMs and exclude KBMs (by neglecting compressional perturbations) reveal strong sensitivity of the heat flux to parallel dissipation and velocity space resolution. With sufficient resolution or dissipation to avoid numerical instabilities, recent MTM-only simulations saturate cleanly at much reduced electron heat flux. We find that including compressibility can unleash a KBM-like instability which drives very large heat fluxes (orders of magnitude greater than the available heating power). The saturated fluxes are sensitive to equilibrium flow shear, and at mid-radius diamagnetic levels of flow shear can reduce the fluxes to much lower values.https://cassyni-user-files-prod.s3.amazonaws.com/FztUMXK8TCHUY3D2GPtquY https://cassyni.com/events/CYy769JSKwtsWhVF5YMM73/abstract https://cassyni-user-files-prod.s3.amazonaws.com/vSWjmkFZSLeYdg7PEo3xa https://cassyni.com/slides/outline/WLLUsP7DXnkrgZb6Jvhk4M https://cassyni.com/events/WLLUsP7DXnkrgZb6Jvhk4M/abstract https://cassyni-user-files-prod.s3.amazonaws.com/YCSDKGmBJ9zGEemEkF3vNS https://cassyni.com/events/WLLUsP7DXnkrgZb6Jvhk4M?videoPreview=1 The Effects of Dust Charging in Space and the Laboratorynohttps://cassyni.com/events/WLLUsP7DXnkrgZb6Jvhk4M?videoPreview=12025-10-02T15:00:00+00:002327.2Journal of Plasma PhysicsMicroscopic particulates—commonly referred to as “dust”—are ubiquitous in both space and laboratory plasmas, where they can fundamentally reshape plasma dynamics, composition, and evolution. On airless solar system bodies such as the Moon or asteroids, the continuous exposure to solar wind plasma, ultraviolet radiation, and micrometeoroid bombardment drives complex charging, mobilization, and transport processes that shape surface environments and influence future exploration activities. In terrestrial contexts, even trace amounts of dust can have outsized impacts: they can compromise semiconductor manufacturing, degrade accelerator beam performance, and, in magnetic confinement fusion devices, trigger major operational disruptions through erosion- and redeposition-induced particle generation. Understanding the underlying physics of dust charging, transport, and plasma coupling is therefore essential across a wide range of disciplines—from planetary science and heliophysics to materials processing and fusion energy research. This presentation will highlight recent advances from in situ space measurements and complementary laboratory experiments that together offer new perspectives on dust–plasma interactions. These results deepen our physical understanding of dusty plasmas in natural and industrial environments and point to innovative strategies for mitigating dust-related hazards in future space missions and next-generation plasma technologies.https://cassyni-user-files-prod.s3.amazonaws.com/YCSDKGmBJ9zGEemEkF3vNS https://cassyni.com/events/RPrSQYdy9DDqHTskJSzkLD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Hx8wk8gT4SZoktdpqMMUpE https://cassyni.com/events/F2aDokEakvhm6dFoRWZzkm/seminar/qa https://cassyni.com/slides/outline/F2aDokEakvhm6dFoRWZzkm https://cassyni.com/events/F2aDokEakvhm6dFoRWZzkm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/R363vCLLsqQr7L9Rjo3zhU https://cassyni.com/events/F2aDokEakvhm6dFoRWZzkm?videoPreview=1 Logic in All Its Dimensions Festschrift for Jean-Yves Béziau's 60th Birthday , Vol. 1nohttps://cassyni.com/events/F2aDokEakvhm6dFoRWZzkm?videoPreview=12026-09-16T14:00:00+00:005383.68Logica UniversalisThe first of the three volumes of a collection of papers in honor of the sixtieth birthday of Jean-Yves Béziau will be presented. The papers have been written by outstanding logicians, mathematicians, historians, and philosophers of logic, and they reflect the current state of the art in research on universal logic and its applications. The book covers a wide range of problems across various fields, including general logic, non-classical logic, the square and other geometrical figures of opposition, philosophy and history of logic, as well as the cultural patterns of thought and the rational or irrational features of love. The volume offers insights that will be of interest to all students and researchers interested in the nature and future of logic.https://cassyni-user-files-prod.s3.amazonaws.com/R363vCLLsqQr7L9Rjo3zhU https://cassyni.com/slides/outline/8botqJe8DePSspJovqK5Mw https://cassyni.com/events/8botqJe8DePSspJovqK5Mw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VrGj18tn19acrJLNFMfbUA https://cassyni.com/events/8botqJe8DePSspJovqK5Mw?videoPreview=1 How to improve airtanker performance?nohttps://cassyni.com/events/8botqJe8DePSspJovqK5Mw?videoPreview=12025-10-23T10:00:00+00:003503.8Department of AeronauticsAirtanker firefighting is a fascinating tool operated to fight wildland fires. Airtankers are, however, developed based on empirical methods and their performance is only discovered after drop tests made above a grid of cups distributed on a plane field with no vegetation (the cup & grid method) developed during the 90’s. Dropping a liquid from an aircraft seems easy to achieve because the released liquid directly falls to the ground due to gravity. However, the fluid dynamics processes that govern this practice is characterized by rich and varied physical phenomena, and controlling the resulting fluid distribution of the drop pattern raises many scientific issues. The liquid column penetration in the air, its large-scale fragmentation and an intense surface atomization give shape to the rainfall produced by the airtanker and the final product deposition onto the canopy. The respective roles of these mechanisms are here described and analyzed in order to determine the parameters of importance for improving airtanker drop performance for more efficient firefighting.https://cassyni-user-files-prod.s3.amazonaws.com/VrGj18tn19acrJLNFMfbUA https://cassyni.com/slides/outline/C5q93wFdn5w7n7uNfhSus https://cassyni.com/events/C5q93wFdn5w7n7uNfhSus/abstract https://cassyni-user-files-prod.s3.amazonaws.com/A88UWdvML9BY7vxqeCyGwx https://cassyni.com/events/C5q93wFdn5w7n7uNfhSus?videoPreview=1 Structures in Oscillating Boundary Layer Flowsnohttps://cassyni.com/events/C5q93wFdn5w7n7uNfhSus?videoPreview=12025-06-12T06:00:00+00:002965.72Leeds Institute for Fluid DynamicsSpanwise wall oscillations in turbulent shear flows can lead to a substantial reduction in skin friction, owing to the apparent disruption of near-wall vortices. However, it is as-yet unclear exactly how wall oscillations affect nonlinear flow structures in these flows, particularly in open boundary layers. This presentation will discuss flow structures responsible for the transition to turbulence in a variety of oscillating boundary layer problems, including the Stokes boundary layer (pure oscillation) and oscillations on sheared boundary layers. It will demonstrate how oscillation affects the physics of the near-wall self sustaining process, creating a new variety of turbulent dynamics.https://cassyni-user-files-prod.s3.amazonaws.com/A88UWdvML9BY7vxqeCyGwx https://cassyni.com/slides/outline/3fKrNUAsq4rRUibTvMc5do https://cassyni.com/events/3fKrNUAsq4rRUibTvMc5do/abstract https://cassyni-user-files-prod.s3.amazonaws.com/F52rgv7tm8cNNtYBDPkwBk https://cassyni.com/events/3fKrNUAsq4rRUibTvMc5do?videoPreview=1 Infection transmission in the built environmentnohttps://cassyni.com/events/3fKrNUAsq4rRUibTvMc5do?videoPreview=12021-02-12T06:00:00+00:003012.68Leeds Institute for Fluid Dynamics COVID-19 has presented us with the most difficult healthcare and societal challenge we have faced in living memory. To understand the mechanisms of transmission we have had to rapidly collect new evidence on the SARS-CoV-2 virus ranging from laboratory data on survival and fluid dynamics studies on droplet dispersion through to epidemiological evidence from outbreaks, contract tracing and cohort studies. Over this time we have become acutely aware of the role that the environment plays in transmission, and how our interactions in indoor spaces determine the risk of infection. But this is not the first disease to be associated with the built environment. Many other respiratory diseases have a clear association with indoor spaces including tuberculosis and influenza. Pathogens such as pseudomonas, legionella are associated with water systems, and even hospital acquired infections such as MRSA have been linked to dispersion within the environment. This presentation sets out what we know about transmission of pathogens in the built environment particular focus on the complex interactions between engineering systems, fluid dynamics, microbiology and the behaviour of people that determine the dispersion, transport and survival of pathogens. Engineering and modelling approaches that can be used to understand mechanisms for transmission and implement mitigation strategies are discussed. The talk discusses how research findings may be used to support practice, and where there gaps in knowledge in both understanding of fundamental processes and the real performance of engineering solutions.https://cassyni-user-files-prod.s3.amazonaws.com/F52rgv7tm8cNNtYBDPkwBk https://cassyni.com/slides/outline/AaQK23EDyUcCyXb3HoB1nV https://cassyni.com/events/AaQK23EDyUcCyXb3HoB1nV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NHzUvJskMRaoZH5iAVyg4N https://cassyni.com/events/AaQK23EDyUcCyXb3HoB1nV?videoPreview=1 Computer Vision-based Full-field Vibration Measurement of Large-scale Structuresnohttps://cassyni.com/events/AaQK23EDyUcCyXb3HoB1nV?videoPreview=12025-09-16T07:00:00+00:002257.6ArtIStE - Artificial Intelligence in Structural EngineeringFull-field displacement measurement is essential in evaluating the structural performance of long-span bridges and high-rise buildings. This study develops a novel, cost-efficient, and high-resolution dynamic displacement monitoring method using one digital camera. The complex real environment and full-field motion are overcome by the developed phase-based optical flow algorithm. The technique is applied to a long-span bridge and a high-rise building. One camera was set at a far distance of over 600 m away to measure the full-field motion of the entire structure. Moreover, a Convolutional Bokeh tracking method is developed to measure the vibration of structures in the evening under low-light conditions.https://cassyni-user-files-prod.s3.amazonaws.com/NHzUvJskMRaoZH5iAVyg4N https://cassyni.com/slides/outline/Hz9zpvSyxhqmcaouYEyBq7 https://cassyni.com/events/Hz9zpvSyxhqmcaouYEyBq7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5VZ3TDUyhXv51RBxiqFNcn https://cassyni.com/events/Hz9zpvSyxhqmcaouYEyBq7?videoPreview=1 Regulatory features determine the evolutionary fate of laterally acquired genes in plantsnohttps://cassyni.com/events/Hz9zpvSyxhqmcaouYEyBq7?videoPreview=12025-08-06T13:00:00+00:00849.12NoneLateral gene transfer (LGT) is widespread in eukaryotes, including in animals and plants where it can fuel adaptive evolution and innovation. However, the factors that influence the integration and long-term retention of transferred genes remain poorly understood. The pangenome of the grass *Alloteropsis* has a high turnover of laterally acquired genes, and here we combine expression, methylation and genomic data to identify factors promoting their long-term persistence. Most transferred genes appear to be degenerating, showing lower expression levels and/or greater truncation compared to vertically inherited homologs. These degenerating genes also show significantly higher levels of DNA methylation, potentially indicating transcriptional silencing. The likelihood of a transferred gene being retained will be influenced by how easily it can be expressed in the recipient genome. In *Alloteropsis*, putatively functional laterally acquired genes had expression levels significantly more similar to their donor xenolog than to their vertically inherited homolog. This pattern suggests that transferred genes may carry cis-regulatory elements encoded on the fragment of DNA that moves between species, facilitating their expression in the new genomic context. Evolutionary novelty may also increase the likelihood that selection retains a transferred gene. However, we only found a significant difference in expression level, not sequence divergence, between donor and recipient orthologs associated with successful lateral gene transfers. Overall, our results show that most transferred genes degrade over time. However, those capable of regulating their own expression are more likely to persist and contribute to long-term evolutionary innovation.https://cassyni-user-files-prod.s3.amazonaws.com/5VZ3TDUyhXv51RBxiqFNcn https://cassyni.com/events/LTQ24Lgc9zcFyXHU5vspZ3/abstract https://cassyni.com/events/Ts85kbPUjrv6U6ow3ojYy3/seminar/qa https://cassyni.com/events/Ts85kbPUjrv6U6ow3ojYy3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EF6n3tq2eUdQdt2nAs8VEe https://cassyni.com/events/Ts85kbPUjrv6U6ow3ojYy3?videoPreview=1 Relaminarising turbulent pipe flow: nonlinear dynamics and optimisationnohttps://cassyni.com/events/Ts85kbPUjrv6U6ow3ojYy3?videoPreview=12026-06-17T10:00:00+00:003369.84Department of AeronauticsSince Reynolds’ experiments, pipe flow has remained a canonical setting for understanding how shear-flow turbulence arises and is sustained, with direct implications for flow control. While most control strategies aim to reduce drag within the turbulent regime, recent experiments have shown a more radical possibility: turbulence can be eliminated altogether, with the flow returning to the much more energy-efficient laminar state. Counter-intuitively, and by mechanisms that are not yet fully explained, complete relaminarisation was achieved by momentarily making the flow even more turbulent or by transiently amplifying wall shear. In this talk, I will discuss how this transition *from* turbulence can be understood and optimised using tools originally developed to study the transition *to* turbulence. Motivated by the experiments, I will first revisit the dynamical-systems picture of pipe flow in state space, from edge states and minimal seeds to the novel concept of the “upper edge” of chaos, which separates turbulent trajectories from high-energy states that relaminarise. I will then formulate relaminarisation as a family of optimisation problems: designing passive or active body forces, modifying the base-flow velocity profile, and finding the smallest perturbations to turbulent states that trigger decay — the reverse analogue of the minimal seed. By analysing the optimal structures and pathways that mediate relaminarisation, I will discuss what insights can be gained into the self-sustaining mechanisms underpinning shear turbulence, and how these processes might be manipulated most efficiently.https://cassyni-user-files-prod.s3.amazonaws.com/EF6n3tq2eUdQdt2nAs8VEe https://cassyni.com/events/gm4JN6fUbZkwF7RAmpR65/seminar/qa https://cassyni.com/slides/outline/gm4JN6fUbZkwF7RAmpR65 https://cassyni.com/events/gm4JN6fUbZkwF7RAmpR65/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Ps2dbb3EGQprwmnYhozghC https://cassyni.com/events/gm4JN6fUbZkwF7RAmpR65?videoPreview=1 Translanguaging, decolonial language awareness (DLA) and language reclamation: Lessons from land-based education with Indigenous youth nohttps://cassyni.com/events/gm4JN6fUbZkwF7RAmpR65?videoPreview=12025-11-19T00:10:00+00:003392.0Linguistics and Applied Language StudiesIn this presentation, I talk about the notion of decolonial language awareness (DLA) (Phyak, 2025) as framework to discuss the transformative role of translanguaging in a language reclamation project. Drawing on the case of participatory land-based education with Indigenous Yaakthung youth in Nepal, I present decolonial praxis, relational thinking, and language reclamation as key aspects of DLA and discuss how translanguaging creates intergenerational spaces through which Indigenous youth develop DLA. I focus on the process of a community-based participatory action research (C-PAR) to engage youth in land-based activities for learning the Indigenous Yaakthung language. I conclude by arguing that Indigenous language education programs need to engage youth learning Indigenous language not just as a system of fixed and bounded rules but as a integral part of Indigenous land, history, and knowledge. https://cassyni-user-files-prod.s3.amazonaws.com/Ps2dbb3EGQprwmnYhozghC https://cassyni.com/events/E2yATTGnT3QcpvME98P9ED/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FqQgWwngdh4wxSZdF7zocr https://cassyni.com/slides/outline/96V7zcoY4TsbRpdt8eg9W5 https://cassyni.com/events/96V7zcoY4TsbRpdt8eg9W5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/98yb84zGng4uFGJqsbLc4n https://cassyni.com/events/96V7zcoY4TsbRpdt8eg9W5?videoPreview=1 Renal Tubular Disordersnohttps://cassyni.com/events/96V7zcoY4TsbRpdt8eg9W5?videoPreview=12021-04-22T08:00:00+00:006530.12Imperial College Renal and Transplant CentreRenal tubular disorders provide critical insights into kidney physiology, particularly regarding salt handling and blood pressure regulation. The kidney’s intrinsic mechanisms, including pressure natriuresis and local autoregulation, play a central role in controlling extracellular fluid volume by modulating sodium reabsorption along distinct nephron segments. Salt reabsorption predominantly occurs in the proximal tubule (70–80%), thick ascending limb (20%), distal convoluted tubule (5–10%), and collecting duct (2–5%), with key transporters such as NKCC2, NCC, ENaC, and associated channels mediating these processes. Monogenic disorders affecting these transporters or their regulatory kinases (e.g., WNK1/4, SPAK/OSR1) elucidate the molecular basis of rare syndromes characterized by hypo- or hypertension, electrolyte imbalances, and acid–base disturbances. For instance, Bartter syndrome results from loss-of-function mutations impairing sodium-chloride transport in the thick ascending limb, causing hypokalemic metabolic alkalosis with hypercalciuria, whereas Gitelman syndrome affects the distal convoluted tubule NCC channel, presenting with hypomagnesemia and hypocalciuria. Conversely, Gordon’s syndrome involves gain-of-function mutations in WNK kinases, leading to hypertension with hyperkalemia. Disorders of the collecting duct, such as Liddle syndrome and pseudohypoaldosteronism type 1, arise from altered ENaC channel activity, impacting sodium reabsorption and potassium secretion. Hormonal regulation via the renin-angiotensin-aldosterone system and natriuretic peptides further modulates tubular function in response to volume status. Clinical case analyses demonstrate the diagnostic utility of integrating biochemical profiles, blood pressure measurements, and genetic insights to differentiate these syndromes. Historical and contemporary studies underscore how monogenic tubular disorders have advanced understanding of renal salt transport, with implications for targeted therapies and management of hypertension and electrolyte disorders.https://cassyni-user-files-prod.s3.amazonaws.com/98yb84zGng4uFGJqsbLc4n https://cassyni.com/events/JyUq2vFvEyseRpLJvnNxGd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6QPhkirwyK6h9Rv2SVqhBU https://cassyni.com/slides/outline/A5REboQ4hgwPYWMGPc7rSH https://cassyni.com/events/A5REboQ4hgwPYWMGPc7rSH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NGCCEkAXzd65i7VoU8XRbC https://cassyni.com/events/A5REboQ4hgwPYWMGPc7rSH?videoPreview=1 Large Engineering Models for instant design validationnohttps://cassyni.com/events/A5REboQ4hgwPYWMGPc7rSH?videoPreview=12026-02-05T19:30:00+00:003745.76AI Institute in Dynamic SystemsThe multi-trillion high-tech industry heavily relies on simulations throughout their development cycles to model complex systems, optimize performance, and validate designs before costly and time intensive prototype fabrication. We are pioneering Large Engineering Model, which represent foundation models for specific engineering verticals (aerodynamics, crash testing, semiconductor design, injection moulding), capable of replacing the full numerical pipeline, and effectively consolidating the traditional, fragmented pipeline into a single interface that provides near-instantaneous feedback to the engineer. Picture a scenario where heat distribution and mechanical stresses are instantly visualized throughout a new semiconductor design! Our main hypothesis is that fully data-driven approaches can parallelize across engineering verticals, with minimal structural intervention, because operational patterns such as geometry representation, meshing algorithms, numerical solving schemes, and postprocessing routines are more uniform than underlying physics. We present our challenges we are facing along our way, and end with our first Large Engineering Model, and its integration into conventional software.https://cassyni-user-files-prod.s3.amazonaws.com/NGCCEkAXzd65i7VoU8XRbC https://cassyni.com/slides/outline/Lwi9jU9Vm83bDFshHiHz1j https://cassyni.com/events/Lwi9jU9Vm83bDFshHiHz1j/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RpVNj5oZjSzzPjgUpnQP7c https://cassyni.com/events/Lwi9jU9Vm83bDFshHiHz1j?videoPreview=1 Session 7B: Natural Hydrogennohttps://cassyni.com/events/Lwi9jU9Vm83bDFshHiHz1j?videoPreview=12025-10-24T11:30:00+00:006238.16Centre for Energy TechnologyThis seminar session addressed the emerging field of natural hydrogen (“white” or “gold” hydrogen) generated by geological processes in the Earth’s subsurface, highlighting its potential as a low-emission energy source. The presentations encompassed exploration frameworks, techno-economic assessments, and engineered mineral hydrogen production. A geoscience-driven exploration approach was outlined, emphasizing the identification of hydrogen-generating source rocks—primarily via serpentinization in ultramafic rocks and radiolysis in radioactive granitic terrains—and the assessment of hydrogen migration, trapping, and preservation within sedimentary systems. Integration of multi-physics geophysical data (gravity, magnetic, electrical) with geological and geochemical observations enables delineation of prospective basement terrains under cover. Techno-economic modeling from an Australian perspective evaluated a natural hydrogen production scenario involving a 650 km² reservoir with 10 wells, estimating capital expenditures around AUD 207 million and a levelized cost of hydrogen near AUD 2.86/kg. Sensitivity analyses identified hydrogen concentration in the gas mixture and production flowrate as critical cost drivers. Complementing natural occurrences, engineered mineral hydrogen production was presented as an approach involving injection of water and catalysts into iron-bearing ultramafic or magnetite-rich formations to accelerate abiotic hydrogen generation via iron oxidation. This method avoids hydraulic fracturing, relies on controlled temperature and catalytic enhancement, and targets abundant geological formations such as ophiolites and banded iron formations globally. Challenges remain in reaction kinetics, multiphase transport, reservoir management, and subsurface monitoring. The session underscored the need for drilling campaigns and technological validation within the next few years to confirm commercial viability and support hydrogen’s role in decarbonization pathways.https://cassyni-user-files-prod.s3.amazonaws.com/RpVNj5oZjSzzPjgUpnQP7c https://cassyni.com/slides/outline/KxQwe6rStCwSYW3hBjpfCq https://cassyni.com/events/KxQwe6rStCwSYW3hBjpfCq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6nVwAsQukzg6zCsSX9HnZC https://cassyni.com/events/KxQwe6rStCwSYW3hBjpfCq?videoPreview=1 Writing an Introduction: Position Your Work and Connect to the Literaturenohttps://cassyni.com/events/KxQwe6rStCwSYW3hBjpfCq?videoPreview=12026-01-28T14:00:00+00:003414.84AAMCThe introduction to any manuscript sets the stage for all that follows. Authors use the introduction to convince readers that they have something important, novel, and useful to share. Here, Bridget O'Brien, PhD, shares strategies for writing an effective introduction that positions an author's work in the field, connects to existing literature, and identifies gaps that their work can address. This webinar is part of the Scholarly Publishing Webinar Series, hosted by Academic Medicine and MedEdPORTAL. For more information on the complete series, see [aamc.org/publishingwebinar](https://www.aamc.org/about-us/mission-areas/medical-education/scholarly-publishing-webinar-series). https://cassyni-user-files-prod.s3.amazonaws.com/6nVwAsQukzg6zCsSX9HnZC https://cassyni.com/slides/outline/8bW3aNyNngCTGG4YpkNtBw https://cassyni.com/events/8bW3aNyNngCTGG4YpkNtBw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KxD28of6Go6r6UntuX2kfp https://cassyni.com/events/8bW3aNyNngCTGG4YpkNtBw?videoPreview=1 Exploring Public Budgeting as a Mechanism for Accountability and Legitimacynohttps://cassyni.com/events/8bW3aNyNngCTGG4YpkNtBw?videoPreview=12026-03-01T22:00:00+00:003387.04SACLThis This paper examines how public budgeting functions as an accountability mechanism to secure legitimacy. Drawing on Weberian traditionalism and Black’s model of legitimacy, it explores a unique case from Indonesia where hereditary monarchy coexists with democratic institutions. Using documentary analysis, interviews, and observation, the study reveals how budgeting processes are shaped by both rational procedures and traditional loyalties. This paper broadens the analytical scope of public budgeting research by demonstrating that accountability mechanisms are not inherently emancipatory or technocratic. Rather, they are embedded in complex legitimacy projects—projects that reflect, sustain, and adapt to the prevailing configurations of power. https://cassyni-user-files-prod.s3.amazonaws.com/KxD28of6Go6r6UntuX2kfp https://cassyni.com/slides/outline/3f217YW8Q6fRsAMCpGftTo https://cassyni.com/events/3f217YW8Q6fRsAMCpGftTo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/YEPQXL9MS26DDkn4vZmf18 https://cassyni.com/events/3f217YW8Q6fRsAMCpGftTo?videoPreview=1 Nano TransMed Youth Forum 2025, Session Inohttps://cassyni.com/events/3f217YW8Q6fRsAMCpGftTo?videoPreview=12025-07-24T01:00:00+00:003395.64None[Nano TransMed (NTM)](https://www.keaipublishing.com/en/journals/nano-transmed/) is an open access peer-reviewed journal. To promote cross-boundary research and linkage between nanotechnology and clinical applications, as well as to build an inclusive, barrier-free communication platform for emerging talent in the community, NTM brings together young scholars across the field to share real-time cutting-edge technologies and the latest research findings. 2025 Session I was held on Jul. 24, 2025. Two speakers shared their latest research.https://cassyni-user-files-prod.s3.amazonaws.com/YEPQXL9MS26DDkn4vZmf18 https://cassyni.com/slides/outline/Aa6Tm7ZUYWRDMyLnBiEpcV https://cassyni.com/events/Aa6Tm7ZUYWRDMyLnBiEpcV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Bw9pcvb54aB2uCnT8xuxkv https://cassyni.com/events/Aa6Tm7ZUYWRDMyLnBiEpcV?videoPreview=1 Closing Remarksnohttps://cassyni.com/events/Aa6Tm7ZUYWRDMyLnBiEpcV?videoPreview=12026-02-25T16:00:00+00:001243.48Researcher to ReaderThis conference conspectus highlighted key tensions and emerging themes in contemporary scholarly communication. A central concern was accountability for research integrity, with an emphasis on the academy’s upstream quality assurance and the current lack of academic credit for peer review, which disincentivizes engagement. Discussions explored the delicate balance between robust governance, standards, and necessary controls on one hand, and the imperative for freedom to publish and author control of copyright on the other. Challenges in "good discrimination" were identified, focusing on distinguishing between legitimate and problematic actors without introducing biases related to institutional prestige or publishing history; author role management and calibrated systems were presented as potential solutions, despite inherent biases in automated and open peer review. The increasing complexity of publishing workflows was critiqued, advocating for simplification, consolidation, and friction reduction, particularly through the broader adoption of journal-agnostic peer review. Finally, the role of Artificial Intelligence was debated, acknowledging its utility as an "intelligent assistant" but also raising significant concerns about embedded biases, its impact on the Global South, and its potential to perpetuate colonial structures. The overarching importance of fostering a unified, collaborative community, encompassing researchers, publishers, librarians, and university leadership, was underscored as crucial for future progress.https://cassyni-user-files-prod.s3.amazonaws.com/Bw9pcvb54aB2uCnT8xuxkv https://cassyni.com/slides/outline/B4k4ooCzyxyGMjsfn9Xcso https://cassyni.com/events/B4k4ooCzyxyGMjsfn9Xcso/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6TnGTCSLKZY74F2PDomMCJ https://cassyni.com/events/B4k4ooCzyxyGMjsfn9Xcso?videoPreview=1 Medical Trainee Contributions to Scholarly Publishing (Lightning Talk)nohttps://cassyni.com/events/B4k4ooCzyxyGMjsfn9Xcso?videoPreview=12026-02-24T13:00:00+00:00547.16Researcher to ReaderMedical trainees pursue scholarly publishing to strengthen residency applications, as academic output enhances individual profiles and program reputation. While residencies value peer-reviewed publications, limited time and experience lead to lower-level evidence. Introducing trainees to other publication types may improve the quality of their scholarship and foster more meaningful novel contributions.https://cassyni-user-files-prod.s3.amazonaws.com/6TnGTCSLKZY74F2PDomMCJ https://cassyni.com/slides/outline/Hyr9ZznEXjen12ZeSA2zf7 https://cassyni.com/events/Hyr9ZznEXjen12ZeSA2zf7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/ALYU4HNLMFnB72LgVDNVyx https://cassyni.com/events/Hyr9ZznEXjen12ZeSA2zf7?videoPreview=1 C2 – Bridging Data Silos in Academia: Smartsheet, Tableau, and Power BI as Catalysts for Transparent Research Analyticsnohttps://cassyni.com/events/Hyr9ZznEXjen12ZeSA2zf7?videoPreview=12026-04-20T12:30:00+00:003139.76Research Analytics SummitAcademic institutions generate large volumes of operational, financial, and research data, yet this information is often siloed across systems and teams. As a result, research administrators frequently rely on manual reporting and static spreadsheets that limit transparency and timely decision making. This session presents a practical, department – led approach to bridging data silos in academia using Smartsheet, Tableau, and Power BI as catalysts for transparent research analytics. The talk focuses on helping participants understand what each tool is best suited for and how these environments can be combined to support real research workflows. Smartsheet is discussed as an operational and workflow platform, Tableau as a tool for exploratory analysis and visual communication, and Power BI as an enterprise layer for integration and governance. A real – world academic example is used to ground the discussion. The session is designed to help attendees avoid common tool misuse and clarify decision – making around analytics platform selection. Session topics: best practices in research analytics; low – code and BI tool integration; responsible use of metrics Tools/software: Smartsheet, Tableau, Power BI Audience: research administrators, research analytics professionals, and institutional research staff Prerequisites: none Key takeaways: participants will gain clarity on how to align analytics tools with research workflows and design scalable, transparent research analytics solutionshttps://cassyni-user-files-prod.s3.amazonaws.com/ALYU4HNLMFnB72LgVDNVyx https://cassyni.com/slides/outline/Ur7Sb31nBoqFXJPg3hGgbw https://cassyni.com/events/Ur7Sb31nBoqFXJPg3hGgbw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XN7pc6PNtnmU7bDiZ9Lxvi https://cassyni.com/events/Ur7Sb31nBoqFXJPg3hGgbw?videoPreview=1 H5 - Data-Driven Growth Planning Using Benchmarking and Emerging Research Strengthsnohttps://cassyni.com/events/Ur7Sb31nBoqFXJPg3hGgbw?videoPreview=12026-04-21T12:30:00+00:001942.96Research Analytics SummitUnderstanding institutional research strengths in core and emerging areas leads to data-driven strategic growth. This session shows how research offices use comparative data to identify opportunity areas to guide strategic planning and align proposal development to build in areas of strength.https://cassyni-user-files-prod.s3.amazonaws.com/XN7pc6PNtnmU7bDiZ9Lxvi https://cassyni.com/events/77arYxYgsfTqiZ7Pfbt1uX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VRAwQB8qE5LjZnpEVU38nr https://cassyni.com/events/Puf2Eq4RCbDgDMoPqB9kpm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/98MGab1xcH6khubspXZGN2 https://cassyni.com/slides/outline/5924UrUUXCBBB5dLv26MMo https://cassyni.com/events/5924UrUUXCBBB5dLv26MMo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PhSwVWV2vZ1m2HfRiFkKXL https://cassyni.com/events/5924UrUUXCBBB5dLv26MMo?videoPreview=1 Tolerance beyond measure: effects of heat load on native Australian plantsnohttps://cassyni.com/events/5924UrUUXCBBB5dLv26MMo?videoPreview=12026-04-24T02:15:00+00:002932.8Institute for Applied EcologyAustralian native plants are remarkably tolerant to a range of environmental conditions in which they grow. As the climate changes, background warming and extreme climatic events are pushing plants closer to their physiological limits. My research focuses on how tolerant native species are to heat and their capacity to adjust their physiology to better cope with heat to maintain function and fitness. I will highlight what we have learned from field, glasshouse, and laboratory experiments, then introduce the Thermal Load Sensitivity framework that uses the common currencies of temperature and time to explore dose-responses. Our current work is using this framework to study the sensitivity of different tissue types and life stages to heat, to integrate impacts of heat across life cycles.https://cassyni-user-files-prod.s3.amazonaws.com/PhSwVWV2vZ1m2HfRiFkKXL https://cassyni.com/slides/outline/7cG5iGi6iUwfY26uThzz5j https://cassyni.com/events/7cG5iGi6iUwfY26uThzz5j/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3n4Je3igapHUrjyfi7Rs6v https://cassyni.com/events/7cG5iGi6iUwfY26uThzz5j?videoPreview=1 Resilient Finance, Stratified Costs: Unmasking Racial Disparities in Disaster-Induced Bank Closuresnohttps://cassyni.com/events/7cG5iGi6iUwfY26uThzz5j?videoPreview=12025-11-19T16:00:00+00:00912.96Center for Black Entrepreneurship, Spelman CollegeThis study investigates the stratified costs borne by Black communities in the aftermath of natural disasters and subsequent bank branch closures. Motivated by the permanent nature of disasters and the increasing trend of "bank deserts," the research explores how the joint shock of these events impacts mortgage credit access. Drawing on theoretical pillars of credit rationing, the loss of "soft information" from local branches, and structural wealth disparities, the analysis highlights how lenders respond by tightening "quiet margins" rather than adjusting interest rates. Data from the Home Mortgage Disclosure Act (HMDA), S&P Global, and SHELDUS disaster records are merged at the county-year level. An econometric approach utilizing triple differences (DDD) identifies the marginal effect of disaster, closure, and race interactions. Complementary local panel projections (LPs) trace the dynamic impact over a five-year window, while event studies and placebo tests confirm robustness. Findings indicate that combined disaster and bank closures lead to increased credit rationing, characterized by stricter screening, including higher debt-to-income ratios and larger cash down payments. This effect is significantly stronger for Black households, resulting in a liquidity squeeze and reduced mortgage credit access. A spillover effect is also observed, with banks in adjacent, non-hit counties adjusting lending practices in anticipation of similar risks. These disparate impacts persist over a five-year period, demonstrating how the loss of local financial intermediaries, exacerbated by natural disasters, disproportionately hinders wealth accumulation in Black communities.https://cassyni-user-files-prod.s3.amazonaws.com/3n4Je3igapHUrjyfi7Rs6v https://cassyni.com/slides/outline/EXLYMqmSrthT2q6Uq9ZvER https://cassyni.com/events/EXLYMqmSrthT2q6Uq9ZvER/abstract https://cassyni.com/events/EXLYMqmSrthT2q6Uq9ZvER?videoPreview=1 Mortality Protection Gap and its Implicationsnohttps://cassyni.com/events/EXLYMqmSrthT2q6Uq9ZvER?videoPreview=12026-05-25T01:00:00+00:002532.76Risk SciencesAbstract: Professor Park's expertise spans diverse domains, including insurance economics, an in-depth understanding of the intersections between insurance and culture, Bonus-Malus System in auto insurance, financial consumer behavior, and Insurtech and Fintech strategy. [Risk sciences](https://www.keaipublishing.com/en/journals/risk-sciences/) aims to foster diverse, multidisciplinary insights in risk sciences, bridging theory and practice through a series of academic activities. This speech record is an excerpt from Prof. Sojung C. Park keynote speech for the China Conference on Insurance and Risk Management, which was held on July 9-12, 2025, in Urumqi, China. https://cassyni.com/slides/outline/QQLFQ9Dq3QhW38Nkb7t4E9 https://cassyni.com/events/QQLFQ9Dq3QhW38Nkb7t4E9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WpaoF3ENtqVUKH1MB3hrr2 https://cassyni.com/events/QQLFQ9Dq3QhW38Nkb7t4E9?videoPreview=1 Conservation Stinks!nohttps://cassyni.com/events/QQLFQ9Dq3QhW38Nkb7t4E9?videoPreview=12026-05-08T02:15:00+00:003440.2Institute for Applied EcologySome of the best conservation solutions stink. In this talk, I explore how smell – an invisible, ever-present layer of every environment – shapes animal decisions, from finding food to avoiding predators. Despite its importance, odour remains one of the most overlooked tools in conservation. "Conservation Stinks" reframes smell as a practical, scalable solution to real-world challenges. Here, I show how odour can protect endangered plants and post-fire recovery by deterring herbivores, manipulate predator behaviour using olfactory misinformation, and improve reintroductions by reshaping risk perception. By altering the "olfactory landscape," we can influence behaviour without fences or lethal control. Drawing on examples from Australia and beyond, this talk highlights scent as a powerful tool for modern wildlife management.https://cassyni-user-files-prod.s3.amazonaws.com/WpaoF3ENtqVUKH1MB3hrr2 https://cassyni.com/slides/outline/GzcBhtWxTYPzH6Br2xGRn5 https://cassyni.com/events/GzcBhtWxTYPzH6Br2xGRn5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8AUm1RWsTVmV3ZArkThiiJ https://cassyni.com/events/GzcBhtWxTYPzH6Br2xGRn5?videoPreview=1 Talk session 7: Numericsnohttps://cassyni.com/events/GzcBhtWxTYPzH6Br2xGRn5?videoPreview=12026-06-10T10:00:00+00:004444.96Nektar++ Development TeamThis session addressed challenges in high-order computational fluid dynamics (CFD) by presenting advancements in solver efficiency, implicit modelling, and performance portability. An incompressible Navier–Stokes solver, utilizing discontinuous Galerkin (DG) methods, was optimized through an 'approximate inverse' preconditioner for the pressure Poisson equation. This strategy, combined with a multigrid framework, yielded solution times comparable to or better than continuous Galerkin (CG) solvers for hexahedral and prismatic meshes, achieving throughputs of 60 million degrees of freedom per second, though tetrahedral mesh performance remains an area of ongoing development. The efficacy of Discontinuous Galerkin Spectral Element Methods (DGSEM) in implicit Large-Eddy Simulations (ILES) was further illuminated through an analytical framework. This approach demonstrated that the intrinsic DG-projection filter effectively preserves kinetic energy, with subgrid-scale modeling errors predominantly located at high wavenumbers and attributed to non-dissipative convective flux terms, thereby justifying DGSEM’s robust ILES performance without explicit models. Furthermore, NektarIR, a domain-specific compiler built on MLIR, was introduced to facilitate performance-portable high-order finite element operations across heterogeneous hardware. The compiler exhibited low overhead (under 1 second) and generated Helmholtz kernels that achieved competitive or superior throughput on CPU targets compared to existing implementations. Initial GPU results show promise, with further optimizations for shared memory utilization underway. These contributions collectively enhance the efficiency, theoretical understanding, and hardware adaptability of high-order CFD methods.https://cassyni-user-files-prod.s3.amazonaws.com/8AUm1RWsTVmV3ZArkThiiJ https://cassyni.com/events/4eQ5YoLqV6YrL6NhZzMKxH/seminar/qa https://cassyni.com/slides/outline/4eQ5YoLqV6YrL6NhZzMKxH https://cassyni.com/events/4eQ5YoLqV6YrL6NhZzMKxH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PTdgsvreqvBevZxnn6eLJa https://cassyni.com/events/4eQ5YoLqV6YrL6NhZzMKxH?videoPreview=1 Where Could AI Actually Help Your Research Analytics Team?nohttps://cassyni.com/events/4eQ5YoLqV6YrL6NhZzMKxH?videoPreview=12026-07-16T16:00:00+00:002846.28Research Evaluation and Analytics Capacity HubResearch analytics and research administration teams are increasingly being asked the same question: What should we actually be doing about AI? For many institutions, the challenge is not a lack of interest, it’s determining where AI could realistically provide value while protecting research integrity, governance, and institutional priorities. This interactive webinar is designed specifically for research analytics and research administration leaders who want a practical, strategic way to evaluate AI opportunities across the research enterprise. Rather than focusing on hype or tools, this session will help participants explore: - where AI may realistically reduce administrative burden, - where it could improve insight generation and research intelligence, - how to evaluate opportunities responsibly, - and how institutions can begin identifying practical next steps. Through live discussion, polling, and a guided opportunity-mapping exercise, attendees will leave with a clearer understanding of where AI may, and may not, make sense for their institution. This session is educational and exploratory in nature. It is not a product demonstration or sales presentation.https://cassyni-user-files-prod.s3.amazonaws.com/PTdgsvreqvBevZxnn6eLJa https://cassyni.com/slides/outline/FWfNZqaP9AjKrNCjBXb1u7 https://cassyni.com/events/FWfNZqaP9AjKrNCjBXb1u7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XUU5QVGJH46ppZTTZ1dXrn https://cassyni.com/events/FWfNZqaP9AjKrNCjBXb1u7?videoPreview=1 Science Advocacy in Action: Uncovering Cryptic Genesnohttps://cassyni.com/events/FWfNZqaP9AjKrNCjBXb1u7?videoPreview=12025-09-16T06:00:00+00:00522.48Journal of VirologyRevisiting a viral genome can rewrite what we know about pathogenesis. In the featured Journal of Virology® Seminar Series talk, Drs. Akihisa Kato and Yasushi Kawaguchi share the story of how they uncovered the neurovirulence factor UL31.6—a cryptic orphan gene in HSV-1 that went unnoticed for years. By applying cutting-edge techniques, they demonstrated that UL31.6 is far from silent—it plays a direct role in how the virus behaves in neurons and contributes to tissue-specific pathogenicity. This work illustrates why scientific curiosity and persistence matter. Even in well-studied pathogens, hidden genetic elements can hold the key to major biological insights. Understanding these factors not only deepens our grasp of virus-host interactions but also opens doors for new therapeutic approaches against neurotropic viruses.https://cassyni-user-files-prod.s3.amazonaws.com/XUU5QVGJH46ppZTTZ1dXrn https://cassyni.com/events/C489F43i4xrgpfuAXsD4NH/seminar/qa https://cassyni.com/slides/outline/C489F43i4xrgpfuAXsD4NH https://cassyni.com/events/C489F43i4xrgpfuAXsD4NH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CWJcm4i3XrQK5wovrWrJgE https://cassyni.com/events/C489F43i4xrgpfuAXsD4NH?videoPreview=1 Fatigue-creep interaction in hemp fibre compositesnohttps://cassyni.com/events/C489F43i4xrgpfuAXsD4NH?videoPreview=12026-06-17T12:30:00+00:001114.56NoneThis research addresses the challenge of estimating the design life of composite structures, particularly in applications like wind turbines, by investigating fatigue-creep interaction in hemp fibre composites. The study employed hemp-epoxy (thermoset) and hemp-Elium (thermoplastic) composites with a 0/90° symmetrical layup and approximately 30% fibre volume fraction. Initial monotonic tests revealed similar strengths but slightly higher stiffness for epoxy, while Elium composites exhibited larger strains at failure due to increased plasticity. Hemp fibres were found to be viscoelastic and highly strain-rate dependent; faster loading increased stiffness by approximately 40% and strength by 8-10%, but decreased strain at failure by about 16%. Dedicated fatigue-creep interaction tests were performed using sinusoidal fatigue cycles combined with dwell periods of 1.8 seconds and 18 seconds. Results showed that introducing dwell periods significantly reduced fatigue life in terms of cycles until failure, with longer dwell periods causing a more pronounced reduction, particularly at higher stress levels. Analysis using Miner's rule indicated that damage accumulation transitioned from fatigue-dominated at shorter dwell periods to creep-dominated at longer dwell periods. While hemp-Elium performed better in high-stress fatigue and hemp-epoxy in creep due to interface effects, their combined fatigue-creep performance was comparable. The findings underscore that hemp composite resistance is strongly strain-rate dependent and that time under load, not solely cycle count, must be a primary consideration for accurate design life estimation. Future work aims to develop comprehensive structural life estimation models.https://cassyni-user-files-prod.s3.amazonaws.com/CWJcm4i3XrQK5wovrWrJgE https://cassyni.com/slides/outline/VqVX2HrVGoifzERAoQx86R https://cassyni.com/events/VqVX2HrVGoifzERAoQx86R/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Wrf7ftkXFYszy9zgJV7PE6 https://cassyni.com/events/VqVX2HrVGoifzERAoQx86R?videoPreview=1 Constrained thermal tolerance and the future of ecosystem servicesnohttps://cassyni.com/events/VqVX2HrVGoifzERAoQx86R?videoPreview=12026-06-02T14:00:00+00:001724.16Understanding how plants and ectothermic organisms tolerate extreme heat is central to predicting climate-change impacts on ecosystems. Biological responses are shaped not only by rising mean temperatures but also by increasingly intense heatwaves, which together impose acute and cumulative thermal stress. In this talk, I synthesise evidence from comparative physiology, evolutionary analyses, and long-term ecological data to show that strong evolutionary constraints on upper thermal tolerance limit adaptive responses to extreme heat, with cascading consequences for ecosystem functioning. Global syntheses of thermal traits across plants and ectotherms demonstrate that upper thermal limits are bounded by strong evolutionary constraints and evolve far more slowly than lower limits. This limited evolutionary flexibility under rapid warming is particularly concerning during heatwaves. Historical collections and resampling studies reveal declines in cold-adapted ectotherms, accompanied by shifts in plant–pollinator interactions and reductions in pollination services. These patterns emerge in landscapes largely free from land-use change, highlighting climate warming as a primary driver of ecological reorganisation. Together, these findings indicate that constrained heat tolerance in plants and ectotherms is already reshaping species interactions and ecosystem function. As climate extremes intensify, progress in conservation and management will depend on embedding ecologically meaningful thermal limits and spatial thermal heterogeneity across landscapes into predictive frameworks.https://cassyni-user-files-prod.s3.amazonaws.com/Wrf7ftkXFYszy9zgJV7PE6 https://cassyni.com/events/TNFVnscs5Wx8x5BPLd9m6D/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GVCPXgGg6Cs88vHLDVLVy8 https://cassyni.com/slides/outline/86xvzDPPxfMGBV8tRKZTQ1 https://cassyni.com/events/86xvzDPPxfMGBV8tRKZTQ1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EzqKTNyG8akirpyMAgRKUi https://cassyni.com/events/86xvzDPPxfMGBV8tRKZTQ1?videoPreview=1 Advanced Intelligent Discovery - Volume 2, Issue 3 rundown (June 2026)nohttps://cassyni.com/events/86xvzDPPxfMGBV8tRKZTQ1?videoPreview=12026-06-23T13:00:00+00:00460.6Inside Advanced Intelligent Discovery's new issue. Fresh off the press in June issue: compostable sensors, AI reading bone, one indecisive chip, equations that find their own mistakes, and satellites, batteries and more. Every paper is open access, so you can read the lot right now.https://cassyni-user-files-prod.s3.amazonaws.com/EzqKTNyG8akirpyMAgRKUi https://cassyni.com/events/UrFZABbDCcTtFzTXSNaDzD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/42FFJ9oBdhmDHH5SToQxXY https://cassyni.com/events/96KPJqiDeJKEYxTURF3ViM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HJ4QfSaCCHQRoXgYrpmqd8 https://cassyni.com/events/PvF6e3t2fAfwHPRpq6s35o/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GWCravb1kzBLXw5mJHcvzi https://cassyni.com/events/WLyoVrxbo64a5fhEcrZEAq/seminar/qa https://cassyni.com/slides/outline/WLyoVrxbo64a5fhEcrZEAq https://cassyni.com/events/WLyoVrxbo64a5fhEcrZEAq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AqiAzovD93v43nmVu7S2Mk https://cassyni.com/events/WLyoVrxbo64a5fhEcrZEAq?videoPreview=1 Reconstructing turbulent velocity and pressure fields from under-resolved noisy particle tracks using physics-informed neural networks, Color particle imaging velocimetry and its applications to various 3D flowsnohttps://cassyni.com/events/WLyoVrxbo64a5fhEcrZEAq?videoPreview=12023-06-27T14:00:00+00:003085.32Experiments in FluidsVolume-resolving imaging techniques are rapidly advancing progress in experimental fluid mechanics. However, reconstructing the full and structured Eulerian velocity and pressure fields from under-resolved and noisy particle tracks obtained experimentally remains a significant challenge. We {adopt and characterize} a method based on Physics-Informed Neural Networks (PINNs). In this approach, the network is regularized by the Navier-Stokes equations to interpolate the velocity data and simultaneously determine the pressure field. We compare this approach to the state-of-the-art Constrained Cost Minimization method. Using data from direct numerical simulations and various types of synthetically generated particle tracks, we show that PINNs are able to accurately reconstruct both velocity and pressure even in regions with low particle density and small accelerations. We analyze both the root mean square error of the reconstructions as well their energy spectra. PINNs are also robust against increasing the distance between particles and the noise in the measurements, when studied under synthetic and experimental conditions. Both the synthetic and experimental datasets used correspond to moderate Reynolds number flows. Three-dimensional three-component (3D-3C) particle imaging velocimetry can be set up even with a single camera when volumetric color-coded illumination is applied to the measurement space. The idea itself was very old as reported a lot in early PIV conferences in 1990s. However, most of PIV developers abandoned to make it feasible in those days due to various limitations struggled for quantitative color extraction required to capture the displacement of color-dependent particle coordinates. Our team spent a long time to overcome such problems to date and reached a certain level of feasibility gradually approaching to tomographic PIV. Our efforts to improve the measurement performance are i) algorithm for easy color calibration, ii) multi-cycle color illumination, iii) intentional particle defocusing, iv) animated color coding, and v) introduction of artificial neural network. In the seminar, I will explain these techniques and their applications including delta-wing wakes, boundary layer on rough surfaces, flows behind wind turbine, wall-impinging vortex rings, and thermal turbulence.https://cassyni-user-files-prod.s3.amazonaws.com/AqiAzovD93v43nmVu7S2Mk https://cassyni.com/slides/outline/NRwC1pEw76yCNDVGb77iEy https://cassyni.com/events/NRwC1pEw76yCNDVGb77iEy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BUfB7N4PvqwMc8WZmTkthC https://cassyni.com/events/NRwC1pEw76yCNDVGb77iEy?videoPreview=1 Prompting for Educators: Effective Communication with AInohttps://cassyni.com/events/NRwC1pEw76yCNDVGb77iEy?videoPreview=12025-06-26T08:00:00+00:003606.24AAMCReady to unlock the true potential of AI in your work as a medical educator? It all starts with knowing how to ask the right questions. In this webinar, you'll discover practical frameworks like TRACI that can help you craft smarter prompts and get better, more reliable results from AI tools. We'll dive into what shapes AI outputs—like bias, data quality, and prompt structure—and practice techniques to sharpen your communication for different educational tasks. Along the way, we'll tackle common pitfalls and ethical challenges, including how to spot misinformation and bias in AI responses. Walk away with easy-to-use strategies that will boost your AI fluency and immediately enhance your teaching, assessment, and scholarship. Objectives: - Apply effective prompting frameworks to interact with AI tools. - Identify factors that influence AI output quality, such as bias and data input quality. - Develop refined prompts to achieve task-specific outputs. - Recognize ethical risks such as AI-generated misinformation and biased content. This webinar is part of the AI Skill Building for Medical Educators Webinar Series, hosted by the AAMC. For more information, see [the complete series webpage](https://www.aamc.org/learn-network/affinity-groups/group-educational-affairs/webinar-series-ai-skill-building-medical-educators).   CME Information - View the last page of the slide deck for complete instructions on earning CME credit for this recording - CME credit for this learning opportunity is organized by Michigan State University College of Human Medicine Office of Continuing Medical Education - You will be prompted to create an account to obtain credithttps://cassyni-user-files-prod.s3.amazonaws.com/BUfB7N4PvqwMc8WZmTkthC https://cassyni.com/events/9cXrknDNdxk2T7RpdHfRS5/seminar/qa https://cassyni.com/slides/outline/9cXrknDNdxk2T7RpdHfRS5 https://cassyni.com/events/9cXrknDNdxk2T7RpdHfRS5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WGoxSLp8PRMpLKEWtRxm8a https://cassyni.com/events/9cXrknDNdxk2T7RpdHfRS5?videoPreview=1 EP3: Probabilistic and Statistical Modeling and Machine Learningnohttps://cassyni.com/events/9cXrknDNdxk2T7RpdHfRS5?videoPreview=12025-04-29T11:00:00+00:005423.44Institute of Natural SciencesChaired by Prof. Shi JIN, this 3rd webinar invites Prof. Lin LIU and Prof. Lei LI to present their latest research on Probabilistic and Statistical Modeling and Machine Learning.https://cassyni-user-files-prod.s3.amazonaws.com/WGoxSLp8PRMpLKEWtRxm8a https://cassyni.com/events/StoffG8SxaEHbjvSrNbZHX/seminar/qa https://cassyni.com/slides/outline/StoffG8SxaEHbjvSrNbZHX https://cassyni.com/events/StoffG8SxaEHbjvSrNbZHX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DdKdTcTGQZCxzVfpmuZ4pE https://cassyni.com/events/StoffG8SxaEHbjvSrNbZHX?videoPreview=1 The Role of Technology in Financial Inclusionnohttps://cassyni.com/events/StoffG8SxaEHbjvSrNbZHX?videoPreview=12025-10-15T12:00:00+00:003590.12Springer Nature Sustainable Development Goals ProgrammeJoin us for a dynamic and thought-provoking webinar exploring how technology and financial inclusion are reshaping the global landscape of work and economic opportunity in alignment with Sustainable Development Goal 8. This session will bring together leading voices from academia and industry to examine the transformative potential of technology in advancing financial inclusion, with a particular focus on the Global South. https://cassyni-user-files-prod.s3.amazonaws.com/DdKdTcTGQZCxzVfpmuZ4pE https://cassyni.com/slides/outline/FWyDpmF8a8vKTcs9Kmusqw https://cassyni.com/events/FWyDpmF8a8vKTcs9Kmusqw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/ET5LeaaPVe3z5eKapoFZLa https://cassyni.com/events/FWyDpmF8a8vKTcs9Kmusqw?videoPreview=1 Session 6 · Forster: Influences and Legacies — “Forster, the Immersive, and A Passage to India”nohttps://cassyni.com/events/FWyDpmF8a8vKTcs9Kmusqw?videoPreview=12024-06-25T12:00:00+00:005781.92Hong Kong Baptist UniversityThis session explored various facets of E. M. Forster’s narrative artistry, adaptations, and comedic techniques. One presentation theorised Forster’s philosophical shift after 1926, arguing his cessation of long fiction writing was not a decline but an embrace of "immersive modernism." This approach moved beyond rationalism and colonial textual registers towards surrounding experience, intuition, and "being in place," conceptualised as "Object-Oriented Phenomenology." *A Passage to India*, particularly its "Temple section," is presented as a culmination of this, manifesting a multifocal perspective where a "storm of presence and being" diminishes human privilege and collapses figure and ground, pushing fiction's capacity beyond static colonial signification. A second paper analysed James Ivory’s film *Howards End* (1992) as a key example of heritage cinema, examining how its "sumptuous pictorialist style" generates nostalgia. The film's meticulously crafted mise-en-scène, encompassing idealized landscapes, symbolic architecture, and evocative props, is shown to reinforce a sense of "pure authenticity" and longing for a bygone era. This visual strategy, however, is noted to risk aestheticizing socio-economic disparities. Finally, the possibilities of Forster’s domestic comedy were explored, referencing his stated influence from Jane Austen. This analysis demonstrated how Forster, in novels such as *A Room with a View* and *Howards End*, employs subtle, understated humour to critique Edwardian gender norms. Scenes revealed female characters performing prescribed "ladylike" roles, highlighting the artificiality and emotional toll of maintaining appearances, while simultaneously exposing the absurdity of societal expectations and the dangers these pose to individual autonomy and authentic human connection.https://cassyni-user-files-prod.s3.amazonaws.com/ET5LeaaPVe3z5eKapoFZLa https://cassyni.com/events/MTLYnBq3JD283goTTfoxhb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VoxVFUaWoPQH7uXHDkLQhk https://cassyni.com/events/69DCENFtHevfuywPh5FvkV/seminar/qa https://cassyni.com/slides/outline/69DCENFtHevfuywPh5FvkV https://cassyni.com/events/69DCENFtHevfuywPh5FvkV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Q1Hi7KjY9Eq9KuyGYmYAMU https://cassyni.com/events/69DCENFtHevfuywPh5FvkV?videoPreview=1 Session 10nohttps://cassyni.com/events/69DCENFtHevfuywPh5FvkV?videoPreview=12023-07-05T01:00:00+00:005712.68New Phytologist Foundation Tropical forests disappear rapidly through deforestation but also have the potential to regrow naturally through secondary succession. To advance successional theory, it is essential to understand how these secondary forests and their assembly vary across broad spatial scales. Here I present some of the main findings of the [2ndFOR research network on secondary forest succession](https://www.2ndFOR.org) that provides a long-term perspective on succession using >100 chronosequence sites across the tropics. We synthesize continental-scale patterns in succession using a functional trait approach and show that the start and pathway of succession varies with climatic water availability. In dry forests, species turnover is driven by drought tolerance traits that are important early in succession and in wet forests by shade tolerance traits that are important later in succession. Based on these successional principles, we propose ecologically sound strategies to improve forest restoration success. Plant functional traits can predict community assembly and ecosystem functioning and are widely used in global models of vegetation dynamics and land–climate feedbacks. Still, we lack a global understanding of how land and climate affect plant traits. A previous global analysis of six traits observed two main axes of variation: (1) size variation at the organ and plant level and (2) leaf economics balancing leaf persistence against plant growth potential. The orthogonality of these two principal components suggests they are differently influenced by environmental drivers. We find these axes persist in a global dataset of 17 in-situ traits across more than 20,000 species. We find with ridge regression models and hierarchical partitioning a dominant joint effect of climate and soil on trait variation. Additional independent climate effects are also observed across most traits, whereas independent soil effects are almost exclusively observed for economics traits. Variation in size traits correlates well with a latitudinal gradient related to water or energy limitation. In contrast, variation in economics traits is better explained by interactions of climate with soil fertility. These findings have the potential to improve our understanding of biodiversity patterns and our predictions of climate change impacts on biogeochemical cycles. Phosphorus limitation is pervasive throughout many pantropical forest communities. However, P acquisition strategies have rarely been examined in Southeast Asian dipterocarp-dominated forests, constraining our understanding of how pantropical species adapt to P limitation. Our study seeks to uncover trade-offs between P acquisition strategies across evolutionarily diverse tropical forest species and how root traits contribute towards inorganic and organic P uptake in nutrient-limited soils. We examined the root morphology, architecture, phosphomonoesterase activity, nutrient content and mycorrhizal colonisation intensity of 33 species in Bukit Timah Nature Reserve and found three main dimensions of trait variation. These dimensions capture multiple aspects of plant P acquisition strategies, including fungal collaboration with mycorrhizal, resource conservatism and variations in phosphatase activity to access organic P. Unexpectedly, arbuscular mycorrhizal colonisation was uncorrelated with the fungal collaboration gradient but correlated negatively with root tissue density on the resource conservatism gradient. Dipterocarps were rarely colonised by ectomycorrhizal but exhibited significantly greater phosphomonoesterase activity. Ultimately, our study expands the known diversity of trait combinations species utilise for P uptake in nutrient-limited environments, while providing evidence that trait ordinations observed from temperate and neotropical ecosystems may not be generalisable to Southeast Asian dipterocarp-dominated forests, mainly due to differences in mycorrhizal associations. Trees provide more than one third of the world’s most important crops and it is increasingly clear that tree crops will play a critical role in the future of sustainable agriculture. Nevertheless, crop research often focuses on annual species, leaving our understanding of the processes and implications of tree domestication poorly defined. Here, I discuss how the tempo and mode of tree domestication is fundamentally different from that of annual crops and propose that many tree species are poised for rapid improvement and introduction into our global food systems. I then provide examples of two projects focused on understanding and conserving tree crop diversity. The first project uses genomic tools to provide insight into the evolution and domestication of Mangifera, a tropical tree genus that includes one of the world’s most important fruits: mango. Next, I introduce a new project that aims to build connections between U.S. botanic gardens and public genebank communities to promote collaborative conservation of taxa in 10 genera of North American fruit and nut trees. Alongside a growing body of research on tree crop diversity, these projects advance our understanding of tree domestication and conservation and refine our visions for sustainable agricultural systems of the future. Banana is the fourth economically important crop worldwide. However, drought stress adversely affects its yield and productivity worldwide. To combat drought stress, bananas have developed complex resistance and adaptation mechanisms. However, there is still a lack of understanding regarding the molecular regulation of drought stress signalling in the Berangan cultivar. Hence, this study determined the drought responses of Berangan at the transcriptome level. This study hypothesized that drought stress could alter gene expression in Berangan and the MYB transcription factor could be activated. To test this hypothesis, RNA-sequencing analysis was performed on well-watered, drought-stressed for 7 days, or water-recovered leaf samples. In total, 767 and 542 differentially expressed genes (DEGs) were identified in drought-stressed and water-recovered samples, respectively, compared to their respective well-watered plants. Notably, 81 of these DEGs were transcription factors, with the highest in the MYB family. To validate the role of the MYB transcription factor, a highly differentially expressed gene, MaMYB86-like, was ectopically expressed in yeast, and analyzed for protein-protein interaction. The results showed that MaMYB86-like-expressing yeast enhanced drought, heat, and salt tolerance through its interaction with MaC4H. These findings suggest that the MaMYB86-like-MaC4H interaction may enhance the production of secondary metabolites to cope with drought stress. Please note this talk will not be available to watch after the live stream. The growing human population and rising global temperatures exacerbate food insecurity and jeopardize crop production. Global climate change trends predict asymmetrical temperature shifts in daytime and night-time temperatures, hampering crop yield dramatically. This necessitates the diversification of agriculture with alternative crops exhibiting climate resilience and superior nutrition profiles. Chenopodium quinoa is a stress-resilient crop with high nutritional value. However, how asymmetrical temperature trends during the day and night affect quinoa growth and yield is unknown. We grew quinoa at control (22/20⁰C, day/night) and exposed it to asymmetrical day (38/22⁰C) and night heating (22/32⁰C) during vegetative and reproductive stages. A multi-level (physiological, biochemical, transcriptional, and metabolic) analysis was performed. The analysis of growth (biomass and yield) and gas exchange (An, gs, E, Ci, ETR, Fv/Fm, NPQ) parameters revealed that heat induces developmental stage-specific effects, wherein the reproductive stage is more heat sensitive, and night heating worsens the impact. The mechanistic basis of these observations is that daytime and night-time heating triggers asymmetric effects on CO2 assimilation and evolution pathways. Furthermore, transcriptome and metabolome data corroborated these results. Overall, we unravel the regulatory networks underlying heat responses in Chenopodium quinoa, which is crucial to expand the cultivation of this future food crop.https://cassyni-user-files-prod.s3.amazonaws.com/Q1Hi7KjY9Eq9KuyGYmYAMU https://cassyni.com/slides/outline/D4xbd3gW6iuoZp8A5wa1VX https://cassyni.com/events/D4xbd3gW6iuoZp8A5wa1VX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/L8KsXdUwsAJ4SgJF97FTVG https://cassyni.com/events/D4xbd3gW6iuoZp8A5wa1VX?videoPreview=1 Urban Analytics Series: Green Space Accessibility and Mental Healthnohttps://cassyni.com/events/D4xbd3gW6iuoZp8A5wa1VX?videoPreview=12024-09-23T01:00:00+00:001813.12The University of Auckland Business SchoolIn this seminar, Dr. Kwan Ok Lee from the National University of Singapore (NUS) will present her latest research on the effects of green space accessibility on mental health, recently published in Nature Mental Health. The study explores how proximity to and the quality of green spaces contribute to psychological well-being, emphasizing the potential benefits of urban planning that prioritizes access to natural environments. By leveraging mobility data from 2 million mobile phone users and advanced analytical techniques, Dr. Lee's research demonstrates that individuals who lived close to green spaces experienced much less mental distress than those who lived farther away during lockdown periods. This seminar will provide valuable insights for academics, policymakers, and urban planners interested in enhancing mental health outcomes through environmental design. https://cassyni-user-files-prod.s3.amazonaws.com/L8KsXdUwsAJ4SgJF97FTVG https://cassyni.com/events/C4RzVyiTVw3gRvZag7XvK7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BXTiiXJQdnPKSYwCkGJaHc https://cassyni.com/events/C4RzVyiTVw3gRvZag7XvK7?videoPreview=1 Beyond the Pandemicnohttps://cassyni.com/events/C4RzVyiTVw3gRvZag7XvK7?videoPreview=12020-05-02T12:00:00+00:004375.04Hong Kong Baptist UniversityThe coronavirus crisis has shown that our wellbeing depends a lot on how we are organised as societies. Human beings may be one species, but how our societies distribute things, make decisions, and deal with conflicts differ across space and time. The current crisis makes it clear that these variations are not merely theoretical, but matters of life and death. What can be done to ensure that Singapore’s governance model, economic strategies, and social arrangements evolve in directions that make the country more resilient and just? Academia.SG’s debut event brings together five Singaporean social scientists in a conversation reflecting on the current crisis and its aftermath.https://cassyni-user-files-prod.s3.amazonaws.com/BXTiiXJQdnPKSYwCkGJaHc https://cassyni.com/events/YJbRgZWgTHrXcUpsxRZDS5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/SbGGk13oRcC5GTHiDnpe7g https://cassyni.com/events/YJbRgZWgTHrXcUpsxRZDS5?videoPreview=1 T12 Text Classificationnohttps://cassyni.com/events/YJbRgZWgTHrXcUpsxRZDS5?videoPreview=12023-08-07T12:00:00+00:00579.28Hong Kong Baptist UniversityAbstract not yet added.https://cassyni-user-files-prod.s3.amazonaws.com/SbGGk13oRcC5GTHiDnpe7g https://cassyni.com/events/2fhAuYhC7pdZ3vpoRjG82H/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NtKNYz9hvbFkCQSH5mAJh4 https://cassyni.com/events/2fhAuYhC7pdZ3vpoRjG82H?videoPreview=1 China’s Covid crisisnohttps://cassyni.com/events/2fhAuYhC7pdZ3vpoRjG82H?videoPreview=12023-01-14T12:00:00+00:001794.16Hong Kong Baptist UniversityChina is struggling to contain the fallout from suddenly ending its draconian Covid-control regime. How bad is the situation and what’s next for the world’s second-largest economy?https://cassyni-user-files-prod.s3.amazonaws.com/NtKNYz9hvbFkCQSH5mAJh4 https://cassyni.com/slides/outline/2BTuaJmximyMaQZZAYmZBB https://cassyni.com/events/2BTuaJmximyMaQZZAYmZBB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UHeaBsYAEyTbYqm8Sj1xgE https://cassyni.com/events/2BTuaJmximyMaQZZAYmZBB?videoPreview=1 Tales of the "fish in your ear": How does Wikipedia help to shape a public narrative on interpreting?nohttps://cassyni.com/events/2BTuaJmximyMaQZZAYmZBB?videoPreview=12021-12-17T12:00:00+00:005047.28Hong Kong Baptist UniversityThis study investigates how Wikipedia contributes to shaping the public narrative surrounding interpreting, addressing the long-standing issue of interpreter invisibility and varied public perceptions. Utilizing a corpus-based approach, English and Chinese Wikipedia articles, talk pages, and Wikinews entries containing keywords such as "interpret*" and "口译/口譯" were collected using WebBootCat and a custom Wiki API. The collected corpora were then analysed with tools including Mark Davis's WikiCorpus, Sketch Engine, LancsBox for collocation, and IBM Watson Natural Language Understanding for sentiment and entity analysis. Findings indicate that English Wikipedia content frequently conflates human language interpreting with computer programming terminology, showing high-frequency collocates like "compiler," "program," and "command." In contrast, Chinese corpora demonstrate a more focused discussion on interpreting as a profession, with terms frequently associated with "research," "work," and government institutions, alongside specific interpreter names such as Zhao Yuxiang. Sentiment analysis of the English "Language interpretation" page revealed an overall positive sentiment (0.36), though with identified negative tones relating to consecutive interpreting drawbacks and specific entities like Nuremberg. The Chinese "口译" page exhibited a higher positive sentiment (0.5) and no negative sentiments, suggesting a more positive public image of the profession in Chinese contexts. Differences were also observed in editing histories and page view stability between the language versions. This analysis positions Wikipedia as a critical "looking glass" that reflects and influences public perceptions of interpreters, revealing nuanced dynamics of language, status, and power. The research suggests that greater engagement from interpreters as Wikipedia editors could enhance professional visibility and correct public understanding.https://cassyni-user-files-prod.s3.amazonaws.com/UHeaBsYAEyTbYqm8Sj1xgE https://cassyni.com/slides/outline/4ehvoj1av4jqwM37iEgBu7 https://cassyni.com/events/4ehvoj1av4jqwM37iEgBu7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Fkr4uC6whsf5ZUnRTSxWWJ https://cassyni.com/events/4ehvoj1av4jqwM37iEgBu7?videoPreview=1 “Let’s Talk of Interesting People”: The Story of Erna Friedländer (1890–1979)nohttps://cassyni.com/events/4ehvoj1av4jqwM37iEgBu7?videoPreview=12024-05-08T12:00:00+00:003926.56Hong Kong Baptist UniversityErna Friedländer studied art in Berlin under Eugene Spiro and in Paris under Mela Muter, André Lhote, and Othon Friesz before embarking on an artistic career in Milan in 1933. Working in an expressionist style developed in German avantgarde circles in the early 20th century and referencing modern dance techniques (Laban Movement), Friedländer’s paintings, watercolors, and monotypes represent a range of genres. After fleeing Nazi persecution and WWII to Hong Kong, she was a painter, printmaker, and teacher at the Hong Kong Working Artist Guild and created portraits of refugees as well as Chinese people and landscapes. What did it mean to bring these techniques, media, and motifs in this way? How was her artwork understood in relation to her status as a female German-Jewish refugee in Hong Kong? And, how can we interpret her monotypes in relation to various European and non-European traditions of printmaking? Friedländer's legacy did not end in Hong Kong: Established in New York City from the mid-1950s, she was an important friend and influential mentor for Ketul Arnold, who knew her between 1973 and 1979, and will share memories of Erna’s stories and teachings from her American period.https://cassyni-user-files-prod.s3.amazonaws.com/Fkr4uC6whsf5ZUnRTSxWWJ https://cassyni.com/slides/outline/D3jCbM1WNr9q6gPan61F81 https://cassyni.com/events/D3jCbM1WNr9q6gPan61F81/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EFeEz8hHujotWxBmLipbPL https://cassyni.com/events/D3jCbM1WNr9q6gPan61F81?videoPreview=1 Freedom, Democracy, and Authoritarianism: Current Societal Context in Hong Kongnohttps://cassyni.com/events/D3jCbM1WNr9q6gPan61F81?videoPreview=12020-05-17T12:00:00+00:00332.28Hong Kong Baptist UniversityThe current societal context in Hong Kong, marked by extensive protests and a pursuit of freedom and democracy, is examined through a philosophical and ethical lens. The analysis draws upon foundational concepts of liberty, specifically distinguishing between negative and positive freedom, and highlights the ongoing demand for negative liberty in the face of government coercive force. J. S. Mill's arguments concerning the importance of freedom of speech, particularly the imperative for governments to permit diverse voices—whether true, partly true, or false—to avoid the establishment of dead dogma, are applied to address observed governmental efforts to suppress political discourse and truth in Hong Kong. Furthermore, the study challenges the notion that East Asian cultures, particularly Chinese, are inherently incompatible with democratic principles. Reference is made to a 1958 manifesto by contemporary Neo-Confucians, which argued for democracy as a means to fulfill certain Confucian virtues, illustrating the historical philosophical compatibility. The discussion also addresses the contemporary belief that the "Chinese model" presents a viable alternative to democracy, framing it as a significant issue in current debates concerning governance in Hong Kong and China.https://cassyni-user-files-prod.s3.amazonaws.com/EFeEz8hHujotWxBmLipbPL https://cassyni.com/slides/outline/NRdLktaBg8nCkxprSrnrJ9 https://cassyni.com/events/NRdLktaBg8nCkxprSrnrJ9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HUnDC2geQeULEY7BbgsDug https://cassyni.com/events/NRdLktaBg8nCkxprSrnrJ9?videoPreview=1 Rethinking Eurasian Connections in the History of Medicinenohttps://cassyni.com/events/NRdLktaBg8nCkxprSrnrJ9?videoPreview=12023-11-29T12:00:00+00:004102.32Hong Kong Baptist UniversityContemporary historians of Chinese medicine agree that medieval Chinese medicine had strong links to the rest of the world, with many of its most common materia medica being of Arabic and West Asian origin. At the same time, they maintain that the medical theories of medieval Chinese medicine remained entirely disconnected from foreign traditions of healing. This talk questions this scholarly consensus. It outlines the strong resemblances with Galenic medical theories found in a little-known Yuan period medical treatise, On the Art of Nourishing Life (1338), and argues that these resemblances were the result of an hitherto overlooked knowledge transmission, that is the transmission of Galenic medical ideas to pre-modern China. Although at first sight, the treatise appears to be composed entirely within the framework of traditional Chinese medicine, it is actually a translation: Its author has rearranged preexisting emic notions and concepts and put them to work to ‘translate’ some of the core theories of Galenic medicine into a Chinese medical framework. Based on these findings, I will argue that (1) in contrast to the current scholarly consensus Chinese medicine did not develop in isolation; it was inextricably entwined with the history of Eurasian medical traditions long before encountering Western medicine in the 19th– 20th century. (2) Galenic humoral theories were not alien to Chinese medicine; they were an important vehicle for the Eurasian transfer of medical ideas.https://cassyni-user-files-prod.s3.amazonaws.com/HUnDC2geQeULEY7BbgsDug https://cassyni.com/slides/outline/NvGwoaDi7bLFkjMk3J5eZT https://cassyni.com/events/NvGwoaDi7bLFkjMk3J5eZT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UeMwhRKPg13DP3znSTFQn2 https://cassyni.com/events/NvGwoaDi7bLFkjMk3J5eZT?videoPreview=1 Voices in Hong Kong with Eddie Tay, Jason Lee, Dave McKirdy, Louise Leung and Melanie Honohttps://cassyni.com/events/NvGwoaDi7bLFkjMk3J5eZT?videoPreview=12021-10-02T12:00:00+00:005114.72Hong Kong Baptist UniversityThis seminar featured four Anglophone poets presenting diverse "Voices in Hong Kong," exploring the city's influence on their work and sense of place. Dave McKirdy’s work drew on his immigrant experience from Scotland, chronicling life in colonial and post-colonial Hong Kong through themes of class, cultural assimilation, and local traditions. Louise Leung, a Hong Kong native, explored post-colonial identity, education as privilege, and new immigrant experiences, often through specific Cantonese cultural markers and local vernacular. Jason Eng Hun Lee, a long-term resident, presented wistful and melancholic reflections on fatherhood, urban landscapes, and marginalized figures, aiming for a deeply personal engagement with the city. Eddie Tay, whose work is informed by 18 years in Hong Kong and a 'dual vision' with Singapore, employed photography and poetry to explore the surreal and constructed nature of urban life, highlighting linguistic nuances. Discussions further illuminated the multifaceted nature of a 'Hong Kong voice,' emphasizing the city's immigrant ethos, its dynamic character, and the poets’ profound commitment to its evolving identity, frequently expressed through hybrid linguistic and cultural forms. The seminar underscored the growing importance of English poetry in Hong Kong as a vibrant space for community building and diverse creative expression across generational and linguistic boundaries.https://cassyni-user-files-prod.s3.amazonaws.com/UeMwhRKPg13DP3znSTFQn2 https://cassyni.com/slides/outline/HV9JJ46wHZFBMs7WSP5ra1 https://cassyni.com/events/HV9JJ46wHZFBMs7WSP5ra1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8e26yr4ygsqhodAsQnVRfL https://cassyni.com/events/HV9JJ46wHZFBMs7WSP5ra1?videoPreview=1 Measure F0 in Praat — Ep.09nohttps://cassyni.com/events/HV9JJ46wHZFBMs7WSP5ra1?videoPreview=12021-06-09T12:00:00+00:00175.8Hong Kong Baptist UniversityFundamental frequency (F0), defined as the frequency of vocal fold vibration and perceived as pitch, plays a crucial role in speech analysis, particularly in tone studies. This seminar outlines practical procedures for measuring F0 using Praat, a widely used acoustic analysis software. The approach involves visualizing the F0 contour by selecting a time point within a speech segment and accessing the pitch display, which reveals the fundamental frequency value in hertz. Additionally, Praat’s pitch listing function enables extraction of F0 values across specified intervals, facilitating detailed temporal analysis of pitch variation within vowels. However, limitations arise in certain phonetic contexts where vocal fold behavior complicates F0 extraction; for example, some syllables may not yield a measurable F0 contour due to atypical vocal fold properties during vowel production. These challenges highlight the need for careful interpretation of Praat’s outputs and suggest potential areas for methodological refinement. The procedures demonstrated provide a foundational framework for researchers conducting acoustic phonetic analysis, with implications for studies in tone languages and speech prosody.https://cassyni-user-files-prod.s3.amazonaws.com/8e26yr4ygsqhodAsQnVRfL https://cassyni.com/slides/outline/VqMQT9H4G163FYMKQjeai9 https://cassyni.com/events/VqMQT9H4G163FYMKQjeai9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GPTauYctNPaEvEBimSzvXg https://cassyni.com/events/VqMQT9H4G163FYMKQjeai9?videoPreview=1 Narratives from Social Movements and Identity Politics in Hong Kong and Taiwannohttps://cassyni.com/events/VqMQT9H4G163FYMKQjeai9?videoPreview=12020-08-26T12:00:00+00:005837.96Hong Kong Baptist UniversityIn recent months, the Chinese government has taken a number of measures to rein in Hong Kong’s autonomy. The Hong Kong government recently postponed the September 6 election of the city’s legislature by a year. China’s legislature also adopted a controversial national security law for Hong Kong that critics argue will undermine the semi-autonomous territory’s freedoms, sparking new protests in Hong Kong. Taiwan has lent moral support for Hong Kong’s pro-democracy activists, while its democratization and social movements - in particular the Sunflower Movement of 2014 - have been sources of inspiration for Hong Kong’s civil society to resist “mainlandization.” In both places, the younger generation have come to the forefront of these movements. How have the social movements in Taiwan and Hong Kong reinforced each side’s political discourse, objectives, and local identities? How does the Taiwan-Hong Kong connection challenge Beijing’s policies towards both entities? What measures can the United States take to support the democratic rights and freedoms in Hong Kong? This virtual seminar will examine the interconnectedness of Hong Kong and Taiwan’s social movements by bringing together a panel of experts from Taiwan, Hong Kong, and the United States.https://cassyni-user-files-prod.s3.amazonaws.com/GPTauYctNPaEvEBimSzvXg https://cassyni.com/slides/outline/QtsMzJoosRZ1rSdyQFwaz1 https://cassyni.com/events/QtsMzJoosRZ1rSdyQFwaz1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VdNvHAjmsqPLgav8q2tJgW https://cassyni.com/events/QtsMzJoosRZ1rSdyQFwaz1?videoPreview=1 Seoul Day 2 Morning | Virtuous AI: Cultural Evolution, Artificial Intelligence, and Virtuenohttps://cassyni.com/events/QtsMzJoosRZ1rSdyQFwaz1?videoPreview=12024-07-11T12:00:00+00:006931.72Hong Kong Baptist UniversityThis seminar explores the intersection of artificial intelligence (AI), virtue, and human flourishing through philosophical, neuroscientific, and ethical lenses. One analysis, grounded in David Hume’s moral philosophy and supported by neuroscientific evidence on neural coupling, argues that current AI—lacking human-like embodiment and sympathetic capacity—is incapable of possessing natural virtues rooted in human emotions and social communication. Instead, AI may embody “artificial virtues” derived from social conventions, such as safety and transparency, which assist human virtue acquisition but remain distinct from intrinsic human moral sentiments. Another perspective, informed by Buddhist philosophy, distinguishes three types of consciousness—ontological, functional, and unconscious—and contends that AI, possessing only unconscious consciousness, cannot have human-like virtues that arise from mind and personal history. This view emphasizes AI’s role as a tool for social virtue, particularly utilitarian aims of promoting societal well-being, rather than individual moral development. A third contribution examines how AI shapes human integrity across epistemic, practical, and holistic dimensions, highlighting tensions arising from data biases, surveillance, and value capture that constrain users’ capacity for moral agency and flourishing. The analysis underscores the interconnectedness of virtue formation within AI ecosystems and calls for context-sensitive ethical frameworks that recognize structural constraints on integrity. Collectively, these discussions illuminate the challenges and possibilities of integrating AI with human virtue, emphasizing embodiment, consciousness, social context, and the need for socially attuned artificial virtues.https://cassyni-user-files-prod.s3.amazonaws.com/VdNvHAjmsqPLgav8q2tJgW https://cassyni.com/slides/outline/TN7PDj3S4iKWDP7XwwrDhw https://cassyni.com/events/TN7PDj3S4iKWDP7XwwrDhw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VG1CxB4gABgB24KFYzN1XU https://cassyni.com/events/TN7PDj3S4iKWDP7XwwrDhw?videoPreview=1 Drama of Dictatorshipnohttps://cassyni.com/events/TN7PDj3S4iKWDP7XwwrDhw?videoPreview=12024-09-21T12:00:00+00:003387.96Hong Kong Baptist UniversityA special interview with Dr Joseph Scalice on his new book.https://cassyni-user-files-prod.s3.amazonaws.com/VG1CxB4gABgB24KFYzN1XU https://cassyni.com/slides/outline/86ppR4oxwridSo532eFv1j https://cassyni.com/events/86ppR4oxwridSo532eFv1j/abstract https://cassyni-user-files-prod.s3.amazonaws.com/D5tA9JgnPtFsqvGmyk2rwg https://cassyni.com/events/86ppR4oxwridSo532eFv1j?videoPreview=1 Information on Foreign Laws in Government- and Privately-Published Sources in Ming Chinanohttps://cassyni.com/events/86ppR4oxwridSo532eFv1j?videoPreview=12023-09-28T12:00:00+00:003518.36Hong Kong Baptist UniversityThis seminar investigates legal information about aliens and foreign countries collected in two types of source. The first is Ming official accounts of diplomatic missions. The second is popular daily encyclopaedias (riyong leishu 日用類 書) compiled and published in south China during the last few decades of the Ming (1368-1644). These popular works catered to the tastes of the new urban class, which sought knowledge and entertainment from self-studying guidebooks. These two types of source show that the Ming reading public conceived of a world far larger and more complex than earlier generations had imagined. The sources also recognise that although some foreign peoples might have lacked formal penal codes, they were by no means lawless. They acknowledge that communities living outside Ming territory had social orders that different differed significantly from that of the Ming state, but that those alternative modes of justice, though exotic, were not inferior to Chinese legal systems.https://cassyni-user-files-prod.s3.amazonaws.com/D5tA9JgnPtFsqvGmyk2rwg https://cassyni.com/slides/outline/3ALmxELiZHBc3hMh2AYvHb https://cassyni.com/events/3ALmxELiZHBc3hMh2AYvHb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Aa3Dv1ow6Zr6gKwy2QSi4v https://cassyni.com/events/3ALmxELiZHBc3hMh2AYvHb?videoPreview=1 Hollywood in China: Behind the Scenes of the World's Largest Movie Marketnohttps://cassyni.com/events/3ALmxELiZHBc3hMh2AYvHb?videoPreview=12022-12-02T12:00:00+00:004087.28Hong Kong Baptist UniversityChina surpassed North America to become the world ’s largest movie market in 2020. Formerly the focus of exotic fascination in the golden age of Hollywood, today the Chinese are a make-or-break audience for Hollywood’s biggest blockbusters. And movies are now an essential part of China’s global “soft power” strategy: a Chinese real estate tycoon, who until recently was the major shareholder of the AMC theater chain, built the world’s largest film production facility. Behind the curtains, as this brilliant new book reveals, movies have become one of the biggest areas of competition between the world’s two remaining superpowers. Will Hollywood be eclipsed by its Chinese counterpart? No author is better positioned to untangle this riddle than Ying Zhu, a leading expert on Chinese film and media. In fascinating vignettes, Hollywood in China unravels the century-long relationship between Hollywood and China for the first time. Blending cultural history, business, and international relations, Hollywood in China charts multiple power dynamics and teases out how competing political and economic interests as well as cultural values are manifested in the art and artifice of filmmaking on a global scale, and with global ramifications. The book is an inside look at the intense business and political maneuvering that is shaping the movies and the U.S.-China relationship itself—revealing a headlines-grabbing conflict that is playing out not only on the high seas, but on the silver screen.https://cassyni-user-files-prod.s3.amazonaws.com/Aa3Dv1ow6Zr6gKwy2QSi4v https://cassyni.com/events/69Nvv9MChpV2nr7oQUtaYD/seminar/qa https://cassyni.com/slides/outline/69Nvv9MChpV2nr7oQUtaYD https://cassyni.com/events/69Nvv9MChpV2nr7oQUtaYD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DDPKgswJ4PKRz5xNfzLH2W https://cassyni.com/events/69Nvv9MChpV2nr7oQUtaYD?videoPreview=1 Synthetic Turbulence Generation in PyFRnohttps://cassyni.com/events/69Nvv9MChpV2nr7oQUtaYD?videoPreview=12021-04-08T14:00:00+00:002568.08PyFRThe generation of realistic incoming turbulence is often a prerequisite to carrying out accurate scale-resolving simulations of spatially developing unsteady flows around complex geometries, like the ones found in many industrial settings. The challenge of developing synthetic turbulence generation methods that are ideally accurate, flexible, robust and cheap to compute is object of active research and this talk describes our steps in that direction. I will describe an extended version of the Synthetic Eddy Method that is being developed in PyFR and the implementation strategy. I will also present simulation results for two test cases: a plane turbulent channel flow and the turbulent flow over a model high rise building.https://cassyni-user-files-prod.s3.amazonaws.com/DDPKgswJ4PKRz5xNfzLH2W https://cassyni.com/slides/outline/2gxC3st5F4KFg9RTwpyzUm https://cassyni.com/events/2gxC3st5F4KFg9RTwpyzUm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Ctfmb1wCFV746Y7hF4Fp4v https://cassyni.com/events/2gxC3st5F4KFg9RTwpyzUm?videoPreview=1 Mathematical analysis of subwavelength metamaterials: sensors, biomimicry and topological edge modesnohttps://cassyni.com/events/2gxC3st5F4KFg9RTwpyzUm?videoPreview=12021-11-23T14:00:00+00:003880.88MetaMATThe aim of our work is to conduct rigorous analyses of subwavelength scattering problems and use these results to establish the mathematical foundations for the design of high-contrast metamaterials. We will present results that characterise a system’s resonance in terms of the eigenstates of the generalized capacitance matrix. We will use this theory to explore applications including the design of cochlea-inspired metamaterials, enhanced sensors based on exceptional points and tuneable topological wave guides. The talk will discuss results developed in collaboration with Habib Ammari, Erik Orvehed Hiltunen and Sanghyeon Yu, who are all former colleagues from Bryn’s time at ETH Zurich.https://cassyni-user-files-prod.s3.amazonaws.com/Ctfmb1wCFV746Y7hF4Fp4v https://cassyni.com/slides/outline/CttTJsxKEx1PkQTQ1Bap5 https://cassyni.com/events/CttTJsxKEx1PkQTQ1Bap5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9ZWuLUH5a7HwKECWCEYNwg https://cassyni.com/events/CttTJsxKEx1PkQTQ1Bap5?videoPreview=1 Greening the Gulf - Coastal Restoration using Musselsnohttps://cassyni.com/events/CttTJsxKEx1PkQTQ1Bap5?videoPreview=12021-03-23T03:00:00+00:003121.08The Auckland Bioengineering InstituteGreening the Gulf - Coastal Restoration using Mussels A hundred years ago the Hauraki Gulf was home to probably the largest single mussel population in the world - over 500 square kilometres of seabed. Over a period of 60 years Aucklanders and their neighbours ate their way through these mussels, leaving nothing but desolate muddy seafloor behind. Since the fishing stopped in the 1980s the mussels have not shown any sign of recovering at all. Recently, the community group, Revive Our Gulf, has been working with researchers at the University of Auckland in an ambitious project to restore mussel beds to the Hauraki Gulf. This presentation will describe the history, the challenge of what is involved and the progress to date.https://cassyni-user-files-prod.s3.amazonaws.com/9ZWuLUH5a7HwKECWCEYNwg https://cassyni.com/slides/outline/KUy7WVN2mGDYXZCDi4bPaD https://cassyni.com/events/KUy7WVN2mGDYXZCDi4bPaD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/N391nQ14HAbd8cPnt6T3g2 https://cassyni.com/events/KUy7WVN2mGDYXZCDi4bPaD?videoPreview=1 12 Labours Seminar Series (Platform 2): A Physiome modelling platform for precision medicinenohttps://cassyni.com/events/KUy7WVN2mGDYXZCDi4bPaD?videoPreview=12022-07-13T00:00:00+00:003448.56Auckland Bioengineering InstituteThis seminar will present our latest efforts towards developing a Physiome modelling platform for precision medicine. We are currently building this platform to integrate clinical data with computational physiology workflows to produce personalised digital twins of patients. We will describe how we will store data within the platform using a FAIR data management system and outline our plans for deploying the platform and connecting it to health IT systems. This includes efforts towards creating linked databases and a unified clinical data management plan that can be used by researchers in their ethics applications. These efforts aim to maximise secondary use of data, which is essential for integrating workflows being developed by different research groups to create digital twins. We will also present documentation being developed to assist researchers in translating their computational physiology workflows via commercialisation pathways.https://cassyni-user-files-prod.s3.amazonaws.com/N391nQ14HAbd8cPnt6T3g2 https://cassyni.com/events/5epCDMFLUSi4tNjWoPEyqP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RB8Qb8TY2DLLrLrp13UMdG https://cassyni.com/slides/outline/HWQKSPHpQnvsz5iAxUoj2V https://cassyni.com/events/HWQKSPHpQnvsz5iAxUoj2V/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HPByycDzsF1KmWYTvbs9La https://cassyni.com/events/HWQKSPHpQnvsz5iAxUoj2V?videoPreview=1 Quasiperiodic composites: Forward and inverse homogenizationnohttps://cassyni.com/events/HWQKSPHpQnvsz5iAxUoj2V?videoPreview=12021-06-22T14:00:00+00:005449.12MetaMATQuasiperiodic materials present a novel class of metamaterials that possess extraordinary mechanical, thermal, and electromagnetic properties, such as superconductivity, extremely low thermal conductivity, unusual mechanical properties, and diffraction patterns forbidden by crystallographic symmetries. The properties of such materials critically depend on the microstructure of the media. The talk will discuss the effective properties and homogenized equations governing the effective behavior of quasiperiodic composites. I will also address an inverse homogenization problem of reconstructing information about microstructural parameters from known effective properties. An approach to the inverse homogenization problem is based on the Stieltjes analytic representation which involves a spectral measure of a self-adjoint operator. The spectral measure contains all information about the geometry of the composite and can be uniquely recovered from effective measurements given in an interval of frequency. Stieltjes analytic representation also allows us to determine spectral characteristics and establish an analogy between Anderson transition in quantum transport and transition from ordered to disordered behavior in classical transport in composites without scattering or wave interference effects.https://cassyni-user-files-prod.s3.amazonaws.com/HPByycDzsF1KmWYTvbs9La https://cassyni.com/slides/outline/VrcRbUTwPEmjskwyvqNTAd https://cassyni.com/events/VrcRbUTwPEmjskwyvqNTAd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UnAzLXqfzqmVvXtGHh6Vcz https://cassyni.com/events/VrcRbUTwPEmjskwyvqNTAd?videoPreview=1 Metastructures for Wave and Diffusion Phenomenanohttps://cassyni.com/events/VrcRbUTwPEmjskwyvqNTAd?videoPreview=12021-02-02T14:00:00+00:005410.96MetaMATMaterials are often used to manipulate waves and fields. Metamaterials have provided far-reaching possibilities in achieving “extremes” in such wave-matter interaction. Various exciting functionalities have been achieved in exploiting metamaterials and metasurfaces in nanophotonics and nano-optics. We have been exploring how spatiotemporal metamaterials can give us new platforms in structuring light for exploiting waves to do certain useful functions for us. Several scenarios are being investigated in my group. As one scenario, we have been developing metastructure platforms that can perform analog computation, such as solving integral and differential equations and inverting matrices, with waves as waves interact with them. Such “metamaterial machines” can function as wave-based analog computing machines, suitable for micro- and nanoscale integration. Another scenario deals with 4-dimensional (4D) metamaterials, in which temporal variation of material parameters is added to the tools of spatial inhomogeneities for manipulating light-matter interaction with spatiotemporal platforms. These 4D structures can also be used for manipulation of diffusion to achieve asymmetric diffusion and trapping. The third category of structured waves is achieved in the near-zero-index materials and associated photonic doping that exhibit unique features in light-matter interaction, opening doors to exciting new wave-based and quantum optical features. In this talk, I will present some of our ongoing work in the above topics, and will forecast possible future research directions in these paradigms.https://cassyni-user-files-prod.s3.amazonaws.com/UnAzLXqfzqmVvXtGHh6Vcz https://cassyni.com/slides/outline/4fWz7yxHbXbvDcuWhQmf2V https://cassyni.com/events/4fWz7yxHbXbvDcuWhQmf2V/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CZdTf5CLcpoWpVzFU1DvVL https://cassyni.com/events/4fWz7yxHbXbvDcuWhQmf2V?videoPreview=1 Humour and belonging: Insights from two summer scholarsnohttps://cassyni.com/events/4fWz7yxHbXbvDcuWhQmf2V?videoPreview=12021-06-25T16:00:00+00:003299.48Linguistics and Applied Language StudiesWhenever we interact we offer signals of who we are and where we belong. In negotiating our identities with others, humour is an important part of the linguistic toolkit. To explore how we both explicitly and implicitly signal identity through language choices, Sofia offers an analysis of comments from viewers of YouTube vlogs, noting in particular the ways in which we claim the status of ‘New Zealander’ through our use of and responses to humour. The goal is to consider national community alignment and the embedding of identity categories within this asynchronous, written context. Using data from Victoria University of Wellington’s Language in the Workplace project, specifically data involving incomers to New Zealand and outbound New Zealanders, Bryer addresses the ways in which pragmatic understanding is central to the navigation and maintenance of successful workplace relationships. A series of transcribed interactions will demonstrate the use of humour as power, alongside reflections on experience with humour at work. By doing so, Bryer outlines how humour can be a powerful tool to uphold the hegemony of workplace power relations.https://cassyni-user-files-prod.s3.amazonaws.com/CZdTf5CLcpoWpVzFU1DvVL https://cassyni.com/slides/outline/CZvGyYpa2DPaXfRVTPkMch https://cassyni.com/events/CZvGyYpa2DPaXfRVTPkMch/abstract https://cassyni-user-files-prod.s3.amazonaws.com/71LQtPAggRZzvQZEVnuSLW https://cassyni.com/events/CZvGyYpa2DPaXfRVTPkMch?videoPreview=1 Identity and impoliteness on two oppositional Facebook Pagesnohttps://cassyni.com/events/CZvGyYpa2DPaXfRVTPkMch?videoPreview=12022-07-29T04:00:00+00:002983.88Linguistics and Applied Language StudiesCommunity water fluoridation (CWF) is a public health intervention with a long history of intractable, bitter polarisation between its proponents and detractors, which continues today on social media. This presentation reports on Miriam's PhD research into how commenters on two Facebook Pages, one for and one against CWF, use evaluative language and impoliteness to construct identities as partisans in this conflict, struggling over scientific and moral authority and who does and does not belong in their partisan online spaces.https://cassyni-user-files-prod.s3.amazonaws.com/71LQtPAggRZzvQZEVnuSLW https://cassyni.com/slides/outline/3gPWiPkZ8n434z9dWoYCDb https://cassyni.com/events/3gPWiPkZ8n434z9dWoYCDb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XWB9A64pFE3zKRrKNakZFC https://cassyni.com/events/3gPWiPkZ8n434z9dWoYCDb?videoPreview=1 Lifespans of the first animalsnohttps://cassyni.com/events/3gPWiPkZ8n434z9dWoYCDb?videoPreview=12025-08-15T12:00:00+00:001116.28Royal Society PublishingLifespans fundamentally impact life history traits. These traits influence the tempo of biological cycles such as nutrient cycling and macroevolutionary patterns over geological time. Yet, the lifespans of the first animals, found during the Ediacaran Period (~580 – 539 Ma) are not well constrained, limiting our understanding of ecological and evolutionary change of early animals. In this study we use the metabolic theory of ecology to estimate the maximum lifespans and evolutionary rates of ten key Ediacaran taxa, constraining maximum lifespan variation for different environmental temperatures and modularity. We find a large range of different maximum lifespans for Ediacaran taxa (0.53 -30.2 years), with longer lifespans in colder environments and for modular organisms (up to 40.2 years). Evolutionary rates were most impacted by environmental temperature, with the fastest evolutionary rates found in small, warm-water taxa have. Ediacaran organisms predate macro-predation and so do not suffer this key downside of small body size. Therefore, these small, warm-water taxa keep the advantages of these higher evolutionary rates, without the predatory downside. The release from predation coupled to these fast evolutionary rates could help to explain the large morphological and taxonomic diversity found in the shallow-water Ediacaran assemblages, in contrast to the colder, deep-water assemblageshttps://cassyni-user-files-prod.s3.amazonaws.com/XWB9A64pFE3zKRrKNakZFC https://cassyni.com/slides/outline/SthBCk4uM8XP28igfwT7zD https://cassyni.com/events/SthBCk4uM8XP28igfwT7zD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/94vZFh6wEKaoij2B7J5oCz https://cassyni.com/events/SthBCk4uM8XP28igfwT7zD?videoPreview=1 Free boundary regularity in the Stefan problemnohttps://cassyni.com/events/SthBCk4uM8XP28igfwT7zD?videoPreview=12021-10-21T13:00:00+00:004165.2Partial Differential Equations and ApplicationsThe Stefan problem describes phase transitions such as ice melting to water, and it is among the most classical free boundary problems. It is well known that the free boundary consists of a smooth part (the regular part) and singular points. In this talk, I will describe a recent result with Ros-Oton and Serra, where we analyze the singular set in the Stefan problem and prove a series of fine results on its structure. https://cassyni-user-files-prod.s3.amazonaws.com/94vZFh6wEKaoij2B7J5oCz https://cassyni.com/slides/outline/YKrSpthZaXYEEhRYUXH5tZ https://cassyni.com/events/YKrSpthZaXYEEhRYUXH5tZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EfYHsxcxF9C2DQ1GHUcz46 https://cassyni.com/events/YKrSpthZaXYEEhRYUXH5tZ?videoPreview=1 Acoustic metamaterials with digitally virtualized resonancenohttps://cassyni.com/events/YKrSpthZaXYEEhRYUXH5tZ?videoPreview=12020-07-28T14:00:00+00:004573.96MetaMATWe present a platform in constructing acoustic metamaterials with digital electronics feedback, which allows us to realize arbitrary resonating response, as if they are acoustic metamaterials with physical resonance, but now with more engineering degrees of freedom. In the first part of this webinar, we will introduce the essential steps to virtualize an impulse response of acoustic metamaterial to a digital signal processing code, demonstrating hugely tunable resonating frequency, strength and linewidth. It also allows arbitrary specifications of bulk modulus, density and Willis parameters with controllable bandwidth. In the second part, we will investigate impact of these arbitrary material parameters to explore active time-varying systems. Specifically, high efficiency on frequency conversion is experimentally demonstrated by tailor-made time-varying response function. Its application with material gain and loss being alternating in time is also investigated.https://cassyni-user-files-prod.s3.amazonaws.com/EfYHsxcxF9C2DQ1GHUcz46 https://cassyni.com/slides/outline/FXnH92BqFbnPjtjYJx1LyK https://cassyni.com/events/FXnH92BqFbnPjtjYJx1LyK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6YzoFmj4FErmwYGexngh9g https://cassyni.com/events/FXnH92BqFbnPjtjYJx1LyK?videoPreview=1 PDE problems that arise from machine learningnohttps://cassyni.com/events/FXnH92BqFbnPjtjYJx1LyK?videoPreview=12020-09-14T15:00:00+00:003521.48Partial Differential Equations and ApplicationsTwo kinds of PDE problems arise from machine learning. The continuous formulation of machine learning naturally gives rise to some very elegant and challenging PDE (more precisely partial differential and integral equations) problems. It is likely that understanding these PDE problems will become fundamental issues in the mathematical theory of machine learning. Machine learning - based algorithms for PDEs also lead to new questions about these PDEs, for example, new kinds of a priori estimates that are suited for the machine learning model.I will discuss both kinds of problems.https://cassyni-user-files-prod.s3.amazonaws.com/6YzoFmj4FErmwYGexngh9g https://cassyni.com/slides/outline/LxyAsoLNtMjHqUUMop1rUD https://cassyni.com/events/LxyAsoLNtMjHqUUMop1rUD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/jgA47Agy2Tmxgt65hGq4S https://cassyni.com/events/LxyAsoLNtMjHqUUMop1rUD?videoPreview=1 MRI metamaterialsnohttps://cassyni.com/events/LxyAsoLNtMjHqUUMop1rUD?videoPreview=12022-01-25T14:00:00+00:004004.48MetaMATMagnetic resonance imaging (MRI) relies on a precise control of spin magnetic moments in the body tissues. To achieve such control, one needs to induce a uniform radiofrequency (RF) magnetic field flux (B1+) across the imaged volume. In 7T MRI scanners, the proton (1H) Larmor frequency reaches 300 MHz. Due to the high relative permittivity of human tissues, the associated RF wavelength can shrink down to 11 cm, which is comparable to the dimensions of some human organs. Consequently, spatially varying phase and amplitude of the RF fields generate signal inhomogeneities across the image. For head imaging, signal losses become strongly visible in the temporal lobes and cerebellum regions of the brain. Different approaches have been implemented to improve B1+ field uniformity of transmit coils such as passive and active RF shimming. Active RF shimming is based on coils with multiple independently controllable transmit elements or channels. These additional degrees of freedom can be exploited to mitigate B1+ inhomogeneities. But, it raises challenges in terms of workflow and patient safety (specific absorption rate). In contrast, passive RF shimming relies on the insertion of passive structures between the subject and the coil. Devices based on high-permittivity dielectric materials and/or metamaterials have seen strong developement in the past years. Induced currents (displacement or conduction currents) generate a secondary RF field that corrects the initial B1+ field. This talk will review some of the achievements and remaining challenges of RF passive shimming in high field MRI applications.https://cassyni-user-files-prod.s3.amazonaws.com/jgA47Agy2Tmxgt65hGq4S https://cassyni.com/slides/outline/Qv8P8dzgzfEiUfEdvMfTSV https://cassyni.com/events/Qv8P8dzgzfEiUfEdvMfTSV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/92JiDNWV9c4EEUSc1eTh74 https://cassyni.com/events/Qv8P8dzgzfEiUfEdvMfTSV?videoPreview=1 The onset of turbulence in shear flows - a matter of life and deathnohttps://cassyni.com/events/Qv8P8dzgzfEiUfEdvMfTSV?videoPreview=12021-05-10T14:00:00+00:003206.64Department of AeronauticsIn pipe, channel and Couette flow turbulence arises despite the linear stability of the laminar state and the transition is caused by finite amplitude perturbations. The resulting patches of turbulence remain spatially localized and die eventually. However prior to decay they may infect adjacent laminar regions and seed new patches. Depending which of these processes dominates either the entire flow will relaminarise or turbulence survives. This overall situation is reminiscent to absorbing state phase transitions in statistical mechanics. As shown specifically for Couette flow the transition falls into the directed percolation universality class. In order to resolve the relevant time scales of the flow and to determine the respective critical exponents, experiments with excessively large aspect ratios and observation times are required. In addition I will discuss further complications that arise in pressure driven flows such as pipes and channels. Finally, if time permits some consequences for turbulence control will be presented.https://cassyni-user-files-prod.s3.amazonaws.com/92JiDNWV9c4EEUSc1eTh74 https://cassyni.com/events/3Bbo6ZXbgWsJfuxMYGGnk5/seminar/qa https://cassyni.com/slides/outline/3Bbo6ZXbgWsJfuxMYGGnk5 https://cassyni.com/events/3Bbo6ZXbgWsJfuxMYGGnk5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BLtsf1dMNGthEcCT9JbXEN https://cassyni.com/events/3Bbo6ZXbgWsJfuxMYGGnk5?videoPreview=1 Deep Learning for Modeling Multiscale Dynamical Systemsnohttps://cassyni.com/events/3Bbo6ZXbgWsJfuxMYGGnk5?videoPreview=12022-04-25T14:00:00+00:004003.32Journal of Computational PhysicsAdvances in deep learning have made constructing, training and deploying deep neural networks more accessible than ever before. Due to their flexibility and predictive accuracy, neural networks have ushered in a new wave of data-driven and data-free modeling for physical phenomena. With several key research breakthroughs, modern deep learning architectures are now more accurate and generalizable facilitating improved physics-informed models. This presentation explores the use of several different deep learning approaches for learning physical dynamics including Bayesian neural networks, generative models, physics-constrained learning and self-attention. By leveraging these recent deep neural network advancements and probabilistic frameworks, powerful multiscale deep learning approaches that incorporate known physical constraints as prior knowledge can be used to accurately predict complex mutliscale dynamical features. We will use such techniques together with generative and adversarial AI models to highlight their potential for inversion tasks including the identification of the heterogeneous conductivity field and reconstructing contaminant release history for subsurface remediation. https://cassyni-user-files-prod.s3.amazonaws.com/BLtsf1dMNGthEcCT9JbXEN https://cassyni.com/slides/outline/69X3VHvdid7fXYBeoAC7vV https://cassyni.com/events/69X3VHvdid7fXYBeoAC7vV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GgLvZioHQNZr2y5woMzDoU https://cassyni.com/events/69X3VHvdid7fXYBeoAC7vV?videoPreview=1 Polynomial Partitioning: The hammer and some (recent algorithmic) nailsnohttps://cassyni.com/events/69X3VHvdid7fXYBeoAC7vV?videoPreview=12022-04-12T17:15:00+00:001788.04Discrete & Computational GeometryNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/GgLvZioHQNZr2y5woMzDoU https://cassyni.com/slides/outline/8cm4iiAFuut9tUfDLr6keR https://cassyni.com/events/8cm4iiAFuut9tUfDLr6keR/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LqeN4UNRfnb6hqHEm993uG https://cassyni.com/events/8cm4iiAFuut9tUfDLr6keR?videoPreview=1 Shear-instability in Internal Kelvin wavesnohttps://cassyni.com/events/8cm4iiAFuut9tUfDLr6keR?videoPreview=12022-04-12T10:40:00+00:001689.76Water WavesInternal waves in the ocean and their laboratory analogues are known to break down via a variety of mechanisms. In this talk I will focus on Direct Numerical Simulations of mode-2 internal waves generated from a lock-release on a laboratory scale. This well-understood process of generation allows us to control the size and shape of the wave formed, for example through a judicious choice of density stratification. In the absence of rotation the internal waves generated, primarily induces stream wise and vertical currents, with span wise currents being the product of small scale three-dimensionalization. When rotation is present, the process of geostrophic adjustment leads to a complex pattern of wave-induced currents oriented in all three coordinate directions. I will demonstrate that this leads to shear instabilities that are trapped near one of the tank walls, it also leads to smaller scale shear instabilities with a stream wise oriented vorticity axis (to our knowledge the first documented case of such instabilities). I will discuss the breakdown into turbulence of these instabilities and the possibilities and challenges of scale up of these simulations to the field scale.https://cassyni-user-files-prod.s3.amazonaws.com/LqeN4UNRfnb6hqHEm993uG https://cassyni.com/slides/outline/D312TTPL3ae8SUJngV8CM https://cassyni.com/events/D312TTPL3ae8SUJngV8CM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/YFuPej441XNawWy81pzuHQ https://cassyni.com/events/D312TTPL3ae8SUJngV8CM?videoPreview=1 Plant signalling and stressnohttps://cassyni.com/events/D312TTPL3ae8SUJngV8CM?videoPreview=12022-05-18T09:00:00+00:005410.04New PhytologistHosted by New Phytologist Advisor, [Andre Kessler](https://benitezalfonso.wordpress.com/), Centre for Plant Science, University of Leeds. Featuring - Amy Jacobsen, author of [Root growth responses to mechanical impedance are regulated by a network of ROS, ethylene and auxin signalling in Arabidopsis](https://nph.onlinelibrary.wiley.com/doi/10.1111/nph.17180) - Joris Jourquin, author of [Two phylogenetically unrelated peptide-receptor modules jointly regulate lateral root initiation via a partially shared signaling pathway in Arabidopsis thaliana](https://nph.onlinelibrary.wiley.com/doi/10.1111/nph.17919) - Yingxuan Ma, author of [FLA11 and FLA12 glycoproteins fine-tune stem secondary wall properties in response to mechanical stresses](https://nph.onlinelibrary.wiley.com/doi/10.1111/nph.17898) https://cassyni-user-files-prod.s3.amazonaws.com/YFuPej441XNawWy81pzuHQ https://cassyni.com/slides/outline/G2V8Qxs8VnBzP4BgJixV4R https://cassyni.com/events/G2V8Qxs8VnBzP4BgJixV4R/abstract https://cassyni-user-files-prod.s3.amazonaws.com/YG2UJG9Pi4BsNSimB18C22 https://cassyni.com/slides/outline/B615x8Pt7CexyxULJFFVLH https://cassyni.com/events/B615x8Pt7CexyxULJFFVLH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/YWECB4spEFedn1cgGbbAZC https://cassyni.com/events/B615x8Pt7CexyxULJFFVLH?videoPreview=1 Plant-animal interactionsnohttps://cassyni.com/events/B615x8Pt7CexyxULJFFVLH?videoPreview=12022-06-09T14:00:00+00:005230.04New Phytologist Hosted by New Phytologist Advisor, Christelle Robert, University of Bern. Featuring - Rocío Escobar-Bravo, author of [Leafminer attack accelerates the development of soil-dwelling conspecific pupae via plant-mediated changes in belowground volatiles](https://nph.onlinelibrary.wiley.com/doi/full/10.1111/nph.17966) - Quint Rusman, author of [Flowers prepare thyselves: Leaf and root herbivores induce specific changes in floral phytochemistry with consequences for plant interactions with florivores](https://nph.onlinelibrary.wiley.com/doi/10.1111/nph.17931) - Camila Souza, author of [Plant-centred sampling estimates higher beta diversity of interactions than pollinator-based sampling across habitats](https://nph.onlinelibrary.wiley.com/doi/10.1111/nph.17334) https://cassyni-user-files-prod.s3.amazonaws.com/YWECB4spEFedn1cgGbbAZC https://cassyni.com/slides/outline/3gH2Fsh1XLM8VNwsLNPkvH https://cassyni.com/events/3gH2Fsh1XLM8VNwsLNPkvH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8ExRW6HVn4xHn6ZEgjkUyk https://cassyni.com/events/3gH2Fsh1XLM8VNwsLNPkvH?videoPreview=1 Exploring ESP/EAP through questionnaire and replication researchnohttps://cassyni.com/events/3gH2Fsh1XLM8VNwsLNPkvH?videoPreview=12022-10-07T03:00:00+00:002893.56Linguistics and Applied Language StudiesResearch suggests that language learners have personal beliefs and knowledge about ways to learn a language (Wenden & Rubin, 1987). Such beliefs and knowledge are conceptualised as metacognitive knowledge (Wenden, 1998). For vocabulary learners, metacognitive knowledge refers to what they know about themselves (e.g. their strengths and weaknesses), about the nature of vocabulary learning, and effective strategies. Moir and Nation’s (2002) study shows evidence that learners with high levels of this metacognitive knowledge are able to approach vocabulary more strategically and effectively, whereas those with gaps in their metacognitive knowledge persisted in learning behaviors they found unfruitful. Through interviews with ten English learners about how they learned vocabulary in an English for Academic Purposes (EAP) course, Moir and Nation (2002) found that most participants showed limited awareness of some important aspects in vocabulary learning, such as need-based word selection, depth of word knowledge, and effective strategies. Only one learner demonstrated a good understanding of how to learn vocabulary effectively. The present study, as a conceptual replication of Moir and Nation (2002), investigated learners’ metacognitive knowledge for vocabulary learning during a language course. Interviews were conducted with eight EAP students learning in the same institution as those in Moir and Nation (2002). The data showed that most participants reported many learning behaviors that are compatible with the good learner in Moir and Nation (2002), such as the awareness of learning different aspects of word knowledge and the need to put new words into use. Word selection and the impact of vocabulary testing did not emerge as noticeable issues in the current study as they did in Moir and Nation (2002). The different cohorts of participants and changes made to the current EAP course might have played an important part in these commonalities and differences in the findings of the two studies. Questionnaires have become one of the most common data collection methods in applied linguistics. However, despite the wide application of questionnaires, it is not uncommon to come across questionnaires without sufficient reliability and validity. The major reason for this could be the questionnaire developers’ insufficient awareness of the questionnaire development and validation theory. In this talk, I report on the main principles and steps I followed to develop and validate two questionnaires about English for Medical Purposes (EMP) coursebooks used in China.https://cassyni-user-files-prod.s3.amazonaws.com/8ExRW6HVn4xHn6ZEgjkUyk https://cassyni.com/slides/outline/MTeQ37VnjBD7ewTsbv8peR https://cassyni.com/events/MTeQ37VnjBD7ewTsbv8peR/abstract https://cassyni-user-files-prod.s3.amazonaws.com/MXxdWLL8MeQj7QSmZPZ2CW https://cassyni.com/events/MTeQ37VnjBD7ewTsbv8peR?videoPreview=1 Robust Background Identification for Video Editingnohttps://cassyni.com/events/MTeQ37VnjBD7ewTsbv8peR?videoPreview=12022-09-21T03:00:00+00:003492.44Computer Graphics GroupExtracting background features for estimating the camera path is a key step in many video editing and enhancement applications. Existing approaches often fail on highly dynamic videos that are shot by moving cameras and contain severe foreground occlusion. In this talk, we present practical methods that can reliably identify background features in complex video, leading to accurate camera path estimation and background layering. Our methods significantly outperform other alternatives, and can be directly used to improve common video editing applications such as stabilization, compositing and background reconstruction. We also show a novel application benefited from the robust background identification and separation, temporal coherent video generation. https://cassyni-user-files-prod.s3.amazonaws.com/MXxdWLL8MeQj7QSmZPZ2CW https://cassyni.com/events/LUMBwkCjrG6xzBdsVwfVqX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CEX91pDQ15eun7d4Ek2qve https://cassyni.com/slides/outline/XLcUxnSHWLHSWTTu7UuBnM https://cassyni.com/events/XLcUxnSHWLHSWTTu7UuBnM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4L5aYhKCGgNLR6SefsNKhY https://cassyni.com/events/XLcUxnSHWLHSWTTu7UuBnM?videoPreview=1 SN Operations Research Forumnohttps://cassyni.com/events/XLcUxnSHWLHSWTTu7UuBnM?videoPreview=12021-02-11T15:00:00+00:00346.04Operations Research ForumNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/4L5aYhKCGgNLR6SefsNKhY https://cassyni.com/slides/outline/Tt5FdzucS8QoUmALTpXEFX https://cassyni.com/events/Tt5FdzucS8QoUmALTpXEFX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8NohYpWsXnCzk16okNb2ut https://cassyni.com/events/Tt5FdzucS8QoUmALTpXEFX?videoPreview=1 Analytics for a Better Worldnohttps://cassyni.com/events/Tt5FdzucS8QoUmALTpXEFX?videoPreview=12022-09-01T12:30:00+00:003849.92In this talk I will describe two Analytics applications that contribute to one or more of the 17 Sustainable Development Goals (SDGs) of the United Nations. The first application is an optimization model to optimize the food supply chain for the World Food Programme. This application received the INFORMS Franz Edelman award in 2021. The second application is an optimization model to optimize health care facility locations in Timor-Leste and stroke center locations in Vietnam. This project is carried out in collaboration with the World Bank. If time permits I will shortly describe current and future activities of the recently initiated Analytics for a Better World Institute (analyticsbw.org).https://cassyni-user-files-prod.s3.amazonaws.com/8NohYpWsXnCzk16okNb2ut https://cassyni.com/slides/outline/NTJhcfVMqnMoaLsYFUbMDw https://cassyni.com/events/NTJhcfVMqnMoaLsYFUbMDw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3UP6nJ6nLVe51cFv9WZqbU https://cassyni.com/events/NTJhcfVMqnMoaLsYFUbMDw?videoPreview=1 A demographic assessment of the Lansing Effect in duckweed (Lemna turionifera Landolt)nohttps://cassyni.com/events/NTJhcfVMqnMoaLsYFUbMDw?videoPreview=12024-10-11T12:00:00+00:00713.0Royal Society PublishingThe Lansing Effect is the propensity for offspring of older parents to have shorter lifespans than offspring of younger parents. A recent review identified two demographic patterns that can produce the Lansing Effect: (1) a greater offspring mortality rate at all offspring ages in offspring of older versus younger parents (greater initial mortality parameter); and (2) an offspring mortality rate that increases more rapidly with offspring age in offspring of older versus younger parents (greater mortality rate parameter). Here, we report on a longitudinal study designed to investigate these patterns, using the duckweed *Lemna turionifera*. We tracked asexually produced offspring that detached from parents that were comparatively young versus old (first versus fifth offspring, respectively). Offspring of older parents lived 15% shorter, on average, than offspring of younger parents, providing evidence of the Lansing Effect. A model-selection approach revealed that the difference between survival curves of first versus fifth offspring was mainly attributable to greater initial mortality in fifth compared to first offspring, though alternative models also received some support. Our study provides a demographic explanation for the Lansing Effect in *L. turionifera* in particular, and provides a method for assessing the survival patterns underpinning the Lansing Effect in general. https://cassyni-user-files-prod.s3.amazonaws.com/3UP6nJ6nLVe51cFv9WZqbU https://cassyni.com/slides/outline/PSdXpfJJ84PgPaPwe217fT https://cassyni.com/events/PSdXpfJJ84PgPaPwe217fT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RDcYaxc2STxigQmQMt5GR4 https://cassyni.com/events/PSdXpfJJ84PgPaPwe217fT?videoPreview=1 Optimal experiment design with adjoint-accelerated Bayesian inferencenohttps://cassyni.com/events/PSdXpfJJ84PgPaPwe217fT?videoPreview=12024-12-16T12:00:00+00:001891.4Data-Centric Engineering JournalWe develop and demonstrate a computationally cheap framework to identify optimal experiments for Bayesian inference ofphysics-based models. We develop the metrics (i) to identify optimal experiments to infer the unknown parameters ofa physics-based model, (ii) to identify optimal sensor placements for parameter inference, and (iii) to identify optimal experiments to perform Bayesian model selection. We demonstrate the framework on thermoacoustic instability, which is an industrially relevant problem in aerospace propulsion, where experiments can be prohibitively expensive. By using an existing densely sampled dataset, we identify the most informative experiments and use them to train the physics-based model. The remaining data are used for validation. We show that, although approximate, the proposed framework can significantly reduce the number of experiments required to perform the three inference tasks we have studied. For example, we show that for task (i), we can achieve an acceptable model fit using just 2.5% of the data that were originally collected.https://cassyni-user-files-prod.s3.amazonaws.com/RDcYaxc2STxigQmQMt5GR4 https://cassyni.com/slides/outline/69wPCjevm31Zihdg5gGkPo https://cassyni.com/events/69wPCjevm31Zihdg5gGkPo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VyLQfAgEKuW4SsmJ9H8beW https://cassyni.com/events/69wPCjevm31Zihdg5gGkPo?videoPreview=1 Candida tropicalis-derived vitamin B3 exerts protective effects against intestinal inflammationnohttps://cassyni.com/events/69wPCjevm31Zihdg5gGkPo?videoPreview=12024-12-04T14:00:00+00:00460.0Microbiome Virtual International ForumMycobiota are an integral part of gut microbiota, and their dysbiosis leads to gastrointestinal disorders. *Candida tropicalis* is increasingly recognized as a major opportunistic pathogen that causes nosocomial bloodstream fungal infections in most tropical countries. However, how commensal *C. tropicalis* interacts with the intestinal barrier and mucosal immunity remains poorly understood during inflammation. In this study, we demonstrated that the reference strain of *C. tropicalis* (MYA-3404) ameliorated intestinal inflammation in murine models of chemically induced colitis and bacterial infection. Intestinal colonization of *C. tropicalis* robustly upregulated the expression of IL-17A and IL-22 by Th17 cells, γδ T cells, and ILC3 to increase barrier function and promote proliferation of intestinal epithelial cells in the colon. Metabolomics analysis of fecal samples from mice colonized with C. tropicalis revealed alterations in vitamin B3 metabolism, facilitating conversion of nicotinamide to nicotinic acid. Although nicotinamide worsened colitis, treatment with nicotinic acid alleviated disease symptoms and enhanced epithelial proliferation and Th17 cell differentiation. Blockade of nicotinic acid production with nicotinamidase inhibitors abrogated the protective effects against colitis induced with *C. tropicalis*. Notably, a clinical *C. tropicalis* strain isolated from patients with candidemia lacked the protective effects against murine colitis observed with the reference strain. In summary, our findings highlight a novel role for *C. tropicalis* in resolving intestinal inflammation by modulating vitamin B3 metabolism.https://cassyni-user-files-prod.s3.amazonaws.com/VyLQfAgEKuW4SsmJ9H8beW https://cassyni.com/slides/outline/AbmpctUei9zpBMPTzL3KYH https://cassyni.com/events/AbmpctUei9zpBMPTzL3KYH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EF6H1PtVc2TdEPz8RdcxXY https://cassyni.com/events/AbmpctUei9zpBMPTzL3KYH?videoPreview=1 Darwinian Quantum Gravity Cosmic Inflationnohttps://cassyni.com/events/AbmpctUei9zpBMPTzL3KYH?videoPreview=12025-02-03T08:00:00+00:001206.44Annals of PhysicsRecent experimental data indicates that of the several approaches to Cosmic Inflation (CI), the most adequate approach is Starobinsky Inflation (SI) which uses a Jordan Frame (JF) where the gravitational constant depends on the quantum fields (QFs), which when transformed into an Einstein Frame (EF) obtains an Inflaton Field (IF) ϕ. To consider the role of decoherence in the IF ϕ, a Darwinian Quantum Gravity perspective called Physics-Cell (PC) approach is considered. In the PC approach, the physics occurs through a QF array Ψ within a 3D time-free medium through the emission and transmission of two types of QFs between PCs, QF array ΔΨ and QF scalar δΨ. The ΔΨ are sent from the PCs based in the rules of the Standard Model of Physics (SMP) calculated within the PCs, the δΨ is associated to the communication of the correction necessary to cancel the effects of the non-infinitesimal value of the PC time-step, and we propose here that δΨ := ϕ. The energy density of δΨ is equal to dark energy’s density thus the IF ϕ energy density is the dark energy, which agrees with other works suggesting likewise. In PC approach, the gravitational effects occur through the transmission of the communication protocols between PCs by the averaging of ΔΨ correlations. This PC approach to CI obtains a reason for both start and end of CI, does not require initial conditions fine-tuning and has an approach to decoherence compatible with contemporary physics’ Quantum Darwinism.https://cassyni-user-files-prod.s3.amazonaws.com/EF6H1PtVc2TdEPz8RdcxXY https://cassyni.com/events/UsnoSovxMTQrLgSMrK5BXj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WcBPX66PKLWVzqbrKRALaJ https://cassyni.com/slides/outline/Bb6eptHazS2gzausNsT5yo https://cassyni.com/events/Bb6eptHazS2gzausNsT5yo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PFxurwZzxyzWBzpjP5TWBx https://cassyni.com/events/Bb6eptHazS2gzausNsT5yo?videoPreview=1 Early Morbimortality in Autologous Hematopoietic Cell Transplantation Performed on Outpatient Basis in Patients with Autoimmune Diseases: Experience in 1700 Patientsnohttps://cassyni.com/events/Bb6eptHazS2gzausNsT5yo?videoPreview=12025-03-19T12:00:00+00:00764.16Bone Marrow TransplantationAutologous hematopoietic cell transplantation (aHSCT) is a viable therapeutic approach in patients with autoimmune diseases. Since June 2015, we have autografted on an outpatient basis 1700 aHSCT patients. The objective was to analyze the salient features of early post-aHSCT complications when performed in the outpatient setting. The primary endpoints were early morbi-mortality-free survival (MFS) and overall survival (OS), whereas secondary endpoints entailed hospital admissions, neutropenic fever, Multiple Sclerosis (MS) flare-up, pneumothorax, hyponatremia and myocarditis. Following the “Mexican Method”; 1700 consecutive aHSCT recipients were analyzed: 1667 with MS, 29 with CIDP and 4 with other autoimmune diseases. A total of 1643 (96.6%) grafts were fully completed in the outpatient setting. The 30-day MFS and 30-day OS were 87.7% and 99.8%, respectively. The 30-day MFS has increased from 94.9% in the first 5 years to 98.2% in the last 5 years (p = 0.0002). The 28-day mortality was 0.17%, whereas the 28-day morbidity was 3.3%. The rate of early complications decreased over time, most likely reflecting a learning curve effect. These data support that employing our method is safe in the short term; as this has been done in a ‘trial’ setting, further research is needed. https://cassyni-user-files-prod.s3.amazonaws.com/PFxurwZzxyzWBzpjP5TWBx https://cassyni.com/events/JWCjb5rpYCiCdsbr2sxTm7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JitDeRQoMEqAV1xDLMMYiz https://cassyni.com/slides/outline/NwxJfM8tHEura7QRqut9VF https://cassyni.com/events/NwxJfM8tHEura7QRqut9VF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DQoUCuhkjBC1sLzpjVNZRg https://cassyni.com/events/NwxJfM8tHEura7QRqut9VF?videoPreview=1 Interconnected pathways link faecal microbiota plasma lipids and brain activity to childhood malnutrition related cognitionnohttps://cassyni.com/events/NwxJfM8tHEura7QRqut9VF?videoPreview=12025-02-18T02:00:00+00:00530.52Microbiome Virtual International ForumMalnutrition affects over 30 million children annually and has profound immediate and enduring repercussions. Survivors often suffer lasting neurocognitive consequences that impact academic performance and socioeconomic outcomes. Mechanistic understanding of the emergence of these consequences is poorly understood. Using multi-system SHAP interpreted random forest models and network analysis, we show that Moderate Acute Malnutrition (MAM) associates with enrichment of faecal *Rothia mucilaginosa*, *Streptococcus salivarius* and depletion of *Bacteroides fragilis* in a cohort of one-year-old children in Dhaka, Bangladesh. These microbiome changes form interconnected pathways that involve reduced plasma odd-chain fatty acid levels, decreased gamma and beta electroencephalogram power in temporal and frontal brain regions, and reduced vocalization. These findings support the hypothesis that prolonged colonization by oral commensal species delay gut microbiome and brain development. While causal links require empirical validation, this study provides insights to improve interventions targeting MAM-associated neurodevelopmental deficits.https://cassyni-user-files-prod.s3.amazonaws.com/DQoUCuhkjBC1sLzpjVNZRg https://cassyni.com/slides/outline/GXahHikqP1ZiPgdDPMA5hw https://cassyni.com/events/GXahHikqP1ZiPgdDPMA5hw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Vek8EXPbbkyfiwksNvDJz2 https://cassyni.com/events/GXahHikqP1ZiPgdDPMA5hw?videoPreview=1 Hosts eject conspecific parasitic eggs according to the egg size in a passerinenohttps://cassyni.com/events/GXahHikqP1ZiPgdDPMA5hw?videoPreview=12025-03-19T12:00:00+00:001208.56Royal Society PublishingConspecific brood parasitism (CBP) is an alternative reproductive tactic in egg-laying species, where a female lays her eggs in the nest of a conspecific. In a population of spotless starlings (Sturnus unicolor), some eggs are ejected from the nest during CBP events. It is unclear whether this ejection is a parasitic strategy (a host egg is ejected) or an anti-parasitism strategy (the parasitic egg is ejected). To clarify this, we genotyped the eggs ejected on the ground and found that 100 % of them were parasitic. Egg discrimination might be based on tactile or visual cues, and we hypothesized that egg size could be used by hosts to eject parasitic eggs. We conducted experiments in the field using dummy eggs of varying sizes. The results showed that starlings were more likely to eject eggs if they were smaller than their own eggs. In contrast, no significant pattern of egg ejection was observed for larger eggs. Our results suggest that starlings use egg volume recognition as an anti-parasitism strategy to avoid the costs of parasitism. Whether this is a frequency-dependent strategy is worth further studies. https://cassyni-user-files-prod.s3.amazonaws.com/Vek8EXPbbkyfiwksNvDJz2 https://cassyni.com/slides/outline/FXtmbYFNs3VJKVwJVP9nGd https://cassyni.com/events/FXtmbYFNs3VJKVwJVP9nGd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Hz54TKXuMiP7EmYsHm5ELW https://cassyni.com/events/FXtmbYFNs3VJKVwJVP9nGd?videoPreview=1 Functional archetypes in the human gut microbiome reveal metabolic diversity, stability, and confound disease-associated signaturesnohttps://cassyni.com/events/FXtmbYFNs3VJKVwJVP9nGd?videoPreview=12025-06-03T14:00:00+00:00777.4Microbiome Virtual International ForumUnderstanding the functional diversity of the gut microbiome is essential for decoding its roles in health and disease. Using a deep-learning framework, we identified three functional archetypes defining healthy adult gut microbiomes, each characterized by specific metabolic potentials: sugar metabolism with branched-chain amino acid and cell wall synthesis (Archetype 1), fatty acid and TCA cycle metabolism (Archetype 2), and amino acid and nitrogen metabolism (Archetype 3). Archetype proximity is linked to stability, with Archetype 2 representing the most resilient state, likely due to its metabolic flexibility. Functional diversity emerged as a confounder in disease-associated microbial signatures. In inflammatory bowel disease, we observed archetype-specific shifts, including increased carbohydrate metabolism in Archetype 1-dominant samples and inflammatory pathways in Archetype 3-dominant samples, suggesting distinct opportunities for microbiome-targeted interventions. This framework addresses key challenges in microbiome research, including inter-individual variability and confounding, while providing robust insights into disease-associated functional shifts and microbial ecosystem dynamics.https://cassyni-user-files-prod.s3.amazonaws.com/Hz54TKXuMiP7EmYsHm5ELW https://cassyni.com/events/NweTQRU8rGirxZAAjpwxKF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DZdjegK5cDEcabGhudtc38 https://cassyni.com/events/3BiHZ5b9HxaDFXA7ihRE3P/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Mh1xeLRzrjJyYcn5GmpGxN https://cassyni.com/events/PSKgZjdYh6Cgn29gXw4vVT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7q1xAy2cdaB2xymXf8iM4A https://cassyni.com/events/A6nkCeeVSNKzkL9h68zAC5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EaGrhZDtQLnmAFf9WCTztn https://cassyni.com/events/Wpz5v4kjyFJugL7yuMzYKf/seminar/qa https://cassyni.com/slides/outline/Wpz5v4kjyFJugL7yuMzYKf https://cassyni.com/events/Wpz5v4kjyFJugL7yuMzYKf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FEq5EnuGok8kduai9bkrcv https://cassyni.com/events/Wpz5v4kjyFJugL7yuMzYKf?videoPreview=1 An assessment of cetacean welfare in the Faroe Islands’ drive huntnohttps://cassyni.com/events/Wpz5v4kjyFJugL7yuMzYKf?videoPreview=12025-10-07T15:05:25+00:001812.16Royal Society PublishingDrive hunts in the Faroes and Japan typically involve prolonged herding of cetaceans into shallow water, forced stranding, restraint and killing using a spinal lance and exsanguination. These methods raise significant animal welfare concerns. This study applies the Five Domains Model to the Faroe Islands’ Grindadráp hunt to consider potential welfare divided the hunt into six stages. Each author independently summarised potential impacts within the Five Domains Model; subsequent group consensus via online meetings assigned likely welfare impacts and affective states. Demonstrable welfare impacts and negative implications and associated affective states. We examined published hunting guidelines and affective states were identified for each Grindadráp stage. The prolonged chase, forced stranding, capture and restraint likely cause chronic and acute physiological stress. The spinal lance may not render animals instantaneously unconscious, raising substantial concerns that some animals may remain aware during exsanguination. Commonly inferred affective states for each domain included: pain, anxiety, disorientation, fear and panic. Given the inherent constraints of the hunt, it is unlikely that the Grindadráp can be undertaken humanely. If the hunt is to continue, substantial reform would be necessary to minimise animal suffering and align with welfare standards applicable to mammals in food production or research.https://cassyni-user-files-prod.s3.amazonaws.com/FEq5EnuGok8kduai9bkrcv https://cassyni.com/slides/outline/JUqDzEcPoXKbS3oRLM6A1K https://cassyni.com/events/JUqDzEcPoXKbS3oRLM6A1K/abstract https://cassyni-user-files-prod.s3.amazonaws.com/YCADmvH5B64zn4SAKDDWuc https://cassyni.com/events/JUqDzEcPoXKbS3oRLM6A1K?videoPreview=1 Extremophile hotspots linked to containerized industrial waste dumping in a deep-sea basin nohttps://cassyni.com/events/JUqDzEcPoXKbS3oRLM6A1K?videoPreview=12025-12-10T02:00:00+00:00853.76Microbiome Virtual International ForumDecaying barrels on the seafloor linked to DDT contamination have raised concerns about the public health implications of decades old industrial waste dumped off the coast of Los Angeles. To explore their contents, we collected sediment cores perpendicular to five deep-sea barrels. The concentration of DDT and its breakdown products were highly elevated relative to control sites yet did not vary with distance from the barrels, suggesting that they were not associated with the contamination. Sediment cores collected through white halos surrounding three barrels were enriched in calcite and had elevated pH. The associated microbial communities were low diversity and dominated by alkalophilic bacteria with metagenome-assembled genomes adapted to high pH. A solid concretion sampled between a white halo and barrel was composed of brucite, a magnesium hydroxide mineral that forms at high pH. Based on these findings, we postulate that leakage of containerized alkaline waste triggered the formation of mineral concretions that are slowly dissolving and raising the pH of the surrounding sediment pore water. This selects for taxa adapted to extreme alkalinity and drives the precipitation of “anthropogenic” carbonates forming white halos, which serve as a visual identifier of barrels that contained alkaline waste. Remarkably, containerized alkaline waste discarded >50 years ago represents a persistent pollutant creating localized mineral formations and microbial communities that resemble those observed at some hydrothermal systems. These formations were observed at one-third of the visually identified barrels in the San Pedro Basin and have unforeseen, long-term consequences for benthic communities in the region.https://cassyni-user-files-prod.s3.amazonaws.com/YCADmvH5B64zn4SAKDDWuc https://cassyni.com/events/PuxsVkjAdZQfpv3ewG5wzm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/SHqRaKxWc3YgzQSPomc6gW https://cassyni.com/events/BZRHy7NQpnT6BCsBaFeb41/abstract https://cassyni-user-files-prod.s3.amazonaws.com/W2g7vPuhvppwGv7TZAcE2A https://cassyni.com/slides/outline/5dhHeAdtN1ezzrChfxpemB https://cassyni.com/events/5dhHeAdtN1ezzrChfxpemB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8iEVUdoNtx8kk4izWN286i https://cassyni.com/events/5dhHeAdtN1ezzrChfxpemB?videoPreview=1 Microbial Contamination of Locally Produced Cosmetic Products in Nigeria: Public Health Concern nohttps://cassyni.com/events/5dhHeAdtN1ezzrChfxpemB?videoPreview=12026-05-12T12:30:00+00:00159.6Microbiome Virtual International ForumThe widespread use of locally produced cosmetic products in Nigeria raises significant concerns regarding microbiological safety and associated public health risks. Inadequately regulated production environments may facilitate contamination, exposing consumers to pathogenic microorganisms through daily skin application. This study evaluated the microbiological quality of commonly used locally produced cosmetic products, including creams, lotions, and oils, to determine the presence and implications of contamination. A descriptive microbiological approach was employed, using standard culture techniques for the isolation and identification of bacterial and fungal contaminants. Contamination was detected across multiple samples. Isolated organisms included Staphylococcus aureus, Pseudomonas aeruginosa, and various fungal species. The findings indicate contamination arising from poor hygiene practices, inadequate production standards, and insufficient preservative systems. The detection of clinically relevant microorganisms underscores a critical public health risk. Strengthening good manufacturing practices and regulatory surveillance is essential to ensure product safety. These findings contribute to global discussions on cosmetic microbiological safety, particularly in low- and middle-income settings.https://cassyni-user-files-prod.s3.amazonaws.com/8iEVUdoNtx8kk4izWN286i https://cassyni.com/slides/outline/GXGr2o65x3Nin8NxHGDtXw https://cassyni.com/events/GXGr2o65x3Nin8NxHGDtXw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XP1jtv9w8ruxuBXYFCTRcJ https://cassyni.com/events/GXGr2o65x3Nin8NxHGDtXw?videoPreview=1 Hidden in plain sound: The scientific potential of house mouse squeaksnohttps://cassyni.com/events/GXGr2o65x3Nin8NxHGDtXw?videoPreview=12025-08-21T23:00:00+00:002132.0Royal Society PublishingThe house mouse (*Mus musculus*) is an emerging model organism for the study of vocal communication. While mice emit a diversity of calls, most publications on adult mouse vocalizations primarily focus on ultrasonic vocalizations (USVs) and only a small proportion include other vocalizations, like squeaks. The representation of squeaks in the literature is not an accurate reflection of their behavioral prevalence, however. Squeaks are common features of the mouse vocal repertoire, emitted under a range of circumstances. In this review, we synthesize the available evidence on mouse squeaks, demonstrating that squeaks are social vocalizations. Although their presence in social situations is evident, the extent to which squeaks convey information about the vocalizer and affect listener behavior across different social contexts has yet to be thoroughly studied. Exploring the nuanced social functions of squeaks and correcting the publication bias that favors USVs will require a coordinated research effort, and we provide several recommendations for meeting these goals. Finally, we highlight the potential of the mouse squeak as an instrument for research beyond ethology, including to investigate the neural basis of vocal communication and conditions that impact communication in humans.https://cassyni-user-files-prod.s3.amazonaws.com/XP1jtv9w8ruxuBXYFCTRcJ https://cassyni.com/events/4eZpEaS9uG7DCeyGKZNeWq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2DvZZSpgfQNEWkvSusjT5Y https://cassyni.com/events/MSXVTvtLckA3mQw4UViVaD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Q8JC7MXrBbNRpomaUsWTrN https://cassyni.com/events/Jym4BDQnGb8utHiUpdA3Mf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/YWu1ZipzyRxwT5EBxbujvN https://cassyni.com/events/QQvKoN3SVz9m6rRLdCz1G1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6uwTKrDyuueXgqRjnp6isp https://cassyni.com/slides/outline/UrRHqxgXcn2F8rdw9nCsmw https://cassyni.com/events/UrRHqxgXcn2F8rdw9nCsmw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Q5LQrv946wXtZ1yatt6yCi https://cassyni.com/events/UrRHqxgXcn2F8rdw9nCsmw?videoPreview=1 Global directions of change in moral norms: a test of the moral argument theorynohttps://cassyni.com/events/UrRHqxgXcn2F8rdw9nCsmw?videoPreview=12025-11-19T11:00:00+00:001225.68Royal Society PublishingHow and why are moral norms for various issues changing across the globe? Moral argument theory uniquely addresses these questions by positing that moral norm change is driven by ‘individualizing’ arguments: concerns about harm, fairness and liberty. We test this theory in a preregistered study of the arguments for both sides of 33 moral issues for which the global directions and rates of norm change were estimated in available longitudinal survey data from 94 societies. We also use available cross-national data to estimate the extent to which each society relies more on individualizing arguments than other kinds of arguments. In support of the theory, norms’ justifiability by individualizing arguments was found to predict their global change, and the effect of individualizing arguments on norm change is stronger in societies that rely more strongly on such arguments. These findings demonstrate a fundamental pattern in the contemporary cultural evolution of morality and highlights the key role played by individualizing arguments.https://cassyni-user-files-prod.s3.amazonaws.com/Q5LQrv946wXtZ1yatt6yCi https://cassyni.com/slides/outline/77thotDSJdeqL7MemgpD5X https://cassyni.com/events/77thotDSJdeqL7MemgpD5X/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RAvpvRdBb6Vmfn22DzmiPp https://cassyni.com/events/77thotDSJdeqL7MemgpD5X?videoPreview=1 PBAF/cBAF reorganization on H3.3 chromatin regulates BMAL1 activity in the absence of circadian negative feedbacknohttps://cassyni.com/events/77thotDSJdeqL7MemgpD5X?videoPreview=12025-11-26T15:00:00+00:001561.68Research Seminars by Springer NatureCircadian rhythms in gene expression are coincident with 24hr dynamics in the recruitment of the core-clock transcription factor heterodimer CLOCK-BMAL1 to chromatin. In the liver, circadian chromatin is characterized by rhythmic histone modifications and the deposition of histone variant H2A.Z. However, other histone variants and remodelers that work in conjunction with CLOCK-BMAL1 on variant chromatin remain poorly understood. Here, we reveal that H3.3 variant histone deposition peaks during the daytime in liver chromatin and that CLOCK-BMAL1 is recruited to H3.3 nucleosomes. Moreover, H3.3:CLOCK-BMAL1 associates with PBAF and BRG1/cBAF complexes - members of the SWI/SNF remodeler family - only during the active phase of the circadian cycle. In clock-disrupted Per1−/−; Per2−/− livers, we observe a depletion in ARID2, the central cog in the molecular assembly of the PBAF complex, accompanied by an increase in H3.3 incorporation. Remarkably, a disassembly of PBAF complex and the concurrent reduction in BRG1 triggers a remodeler reorganization in Per knockout livers, where BRM/cBAF now targets BMAL1 at readily-accessible genomic sites. An abundance of fragile, acetylated H3.3 nucleosomes and a remodeler reorganization provide a mechanistic basis for BMAL1 activity in the absence of PER-mediated negative feedback.https://cassyni-user-files-prod.s3.amazonaws.com/RAvpvRdBb6Vmfn22DzmiPp https://cassyni.com/slides/outline/WpgEf95zYH7v4msioH4M9f https://cassyni.com/events/WpgEf95zYH7v4msioH4M9f/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UhVCZQFXgP73KfiqLVQQar https://cassyni.com/events/WpgEf95zYH7v4msioH4M9f?videoPreview=1 Superfluid Dark Matternohttps://cassyni.com/events/WpgEf95zYH7v4msioH4M9f?videoPreview=12026-02-20T20:00:00+00:001659.0Physics ReportsIn this talk, we introduce the superfluid dark matter framework, in which dark matter is composed of ultralight bosons with repulsive self-interactions that condense into a superfluid phase in galactic environments. The resulting superfluid cores give rise to a rich and distinctive phenomenology on astrophysical scales, including the formation of vortices, the dynamics near supermassive black holes, and modifications to dynamical friction, setting the model apart from the standard cold dark matter paradigm.https://cassyni-user-files-prod.s3.amazonaws.com/UhVCZQFXgP73KfiqLVQQar https://cassyni.com/events/MSPNtnJubwXR2isD5pQxBw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DR6tqD5csPAJnF98rHrvmk https://cassyni.com/slides/outline/Mw6EAizCr7w1gBuC3RyRWD https://cassyni.com/events/Mw6EAizCr7w1gBuC3RyRWD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VJzZ1LV7pvydRCMP7S2eR4 https://cassyni.com/events/Mw6EAizCr7w1gBuC3RyRWD?videoPreview=1 Naturally-selected and sexually-selected wing structures synergistically enhance the attractiveness of katydid acoustic signalsnohttps://cassyni.com/events/Mw6EAizCr7w1gBuC3RyRWD?videoPreview=12026-05-11T14:00:00+00:00788.88Royal Society PublishingNaturally-selected adaptations are often thought to impair the elaboration of conspicuous sexual signals. In katydids, males produce acoustic signals by rubbing together structures on their forewings; specialised forewing cells then radiate this sound. These dedicated sound-producing structures are found on a physically distinct basal area of the forewing, but in many species, the remainder of the wing has evolved enormous, exaggerated blade-like or leaf-like structures under natural selection. We tested whether removal of such adjacent, naturally- selected modifications enhances the attractiveness of male sexual signals by releasing bioacoustic constraints caused by their physical connection on the wing surface. Acoustic and resonance measurements of the leaf-mimic Viadana brunneri before and after removing the non-sound-producing, leaf-mimicking, portion of the forewing demonstrate that these regions decrease the frequency of male song and increase its amplitude (i.e. loudness). Using a playback experiment with calls from the intact versus wing-clipped males, we found that females prefer the lower frequency calls of males with the non-stridulatory portion of their forewings intact. Thus, the function and attractiveness of intraspecific signals can be enhanced by naturally-selected adaptations, contradicting the common assumption that adaptations for mate attraction and predator avoidance represent functional compromises between sexual and natural selection. https://cassyni-user-files-prod.s3.amazonaws.com/VJzZ1LV7pvydRCMP7S2eR4 https://cassyni.com/events/DY6aVjWAnhSfJtigRwoMMP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EVdHE5BRaLAQb4YHQ4651x https://cassyni.com/events/VMNk9ZzoVCmLQo1cqj6w3B/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WBgkpDgmqS1Zx1M5s1Ah6v https://cassyni.com/events/H1ZMbJ369othHkYFSy474Z/seminar/qa https://cassyni.com/slides/outline/H1ZMbJ369othHkYFSy474Z https://cassyni.com/events/H1ZMbJ369othHkYFSy474Z/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9q7mJ5VcspZnrsfKRWYrMC https://cassyni.com/events/H1ZMbJ369othHkYFSy474Z?videoPreview=1 Haemodialysis Researchnohttps://cassyni.com/events/H1ZMbJ369othHkYFSy474Z?videoPreview=12024-03-15T13:30:00+00:005932.04Imperial College Renal and Transplant CentreLeading young researchers describe their current patient-centred research from epidemiological, immunological and psychological perspectives Schedule: 1. 13:30-14:00 Dialysis After Graft Loss - Survival Factors 2. 14:00-14:30 Dialysis After Graft Loss - Immune Injury 3. 14:30-15:00 Patient Related Outcomes with Haemodiafiltrationhttps://cassyni-user-files-prod.s3.amazonaws.com/9q7mJ5VcspZnrsfKRWYrMC https://cassyni.com/slides/outline/G2uU8QbRYC5taDdhbF37Xj https://cassyni.com/events/G2uU8QbRYC5taDdhbF37Xj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7xh4uHsngMej1ZSzSE4QWi https://cassyni.com/events/G2uU8QbRYC5taDdhbF37Xj?videoPreview=1 Accelerating Open Research Practices – How The Open Research Programme Is Creating Change Webinarnohttps://cassyni.com/events/G2uU8QbRYC5taDdhbF37Xj?videoPreview=12023-11-16T03:00:00+00:005312.32UKRNThe last update on the UKRN Open Research Programme (ORP) was in February, and much has happened since as it accelerates open research by providing training, reforming policies, enabling sharing of practice and developing insights and indicators. This webinar will present a summary of recent developments in the Programme, highlight some discussion points to inform its next phase, and give attendees a chance to ask questions.https://cassyni-user-files-prod.s3.amazonaws.com/7xh4uHsngMej1ZSzSE4QWi https://cassyni.com/slides/outline/XM2pgEAaYkBLhcuvPzypFf https://cassyni.com/events/XM2pgEAaYkBLhcuvPzypFf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GDgaCznK5rFdzFBB9FyQnJ https://cassyni.com/events/XM2pgEAaYkBLhcuvPzypFf?videoPreview=1 Researcher’s Toolkit: Practical Tips on ABS Compliance- Part 1nohttps://cassyni.com/events/XM2pgEAaYkBLhcuvPzypFf?videoPreview=12025-05-05T13:00:00+00:00982.92Microbiome Virtual International ForumPart. 1 - The presentation will focus on the legal obligations under Access and Benefit-Sharing (ABS) within research projects, outlining the complex and multilayered compliance requirements researchers must navigate. It will also examine the potential consequences of non-compliance with these obligations.https://cassyni-user-files-prod.s3.amazonaws.com/GDgaCznK5rFdzFBB9FyQnJ