https://cassyni.com/slides/outline/T8rF3JoM9hF5eZstSaPAYM https://cassyni.com/events/T8rF3JoM9hF5eZstSaPAYM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3TDDRQjLZFZLLCtoU1QRtz https://cassyni.com/events/T8rF3JoM9hF5eZstSaPAYM?videoPreview=1 Health equity, diversity and global precision medicinenohttps://cassyni.com/events/T8rF3JoM9hF5eZstSaPAYM?videoPreview=12023-09-28T11:00:00+00:003425.12Cambridge PrismsThis webinar will explore the challenges of health equity, diversity and global precision medicine.https://cassyni-user-files-prod.s3.amazonaws.com/3TDDRQjLZFZLLCtoU1QRtz https://cassyni.com/slides/outline/RAHSyCj8oDxR76PqgzbVzd https://cassyni.com/events/RAHSyCj8oDxR76PqgzbVzd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JBWTPwHoJtvmgsnehX4NjG https://cassyni.com/events/RAHSyCj8oDxR76PqgzbVzd?videoPreview=1 AF1q is a universal marker of neuroblastoma that sustains N-Myc expression and drives tumorigenesisnohttps://cassyni.com/events/RAHSyCj8oDxR76PqgzbVzd?videoPreview=12024-03-11T12:00:00+00:001027.12OncogeneNeuroblastoma is the most common extracranial malignant tumor of childhood, accounting for 15% of all pediatric cancer deaths. Despite significant advances in our understanding of neuroblastoma biology, five-year survival rates for high-risk disease remain less than 50%, highlighting the importance of identifying novel therapeutic targets to combat the disease. MYCN amplification is the most frequent and predictive molecular aberration correlating with poor outcome in neuroblastoma. N-Myc is a short-lived protein primarily due to its rapid proteasomal degradation, a potentially exploitable vulnerability in neuroblastoma. AF1q is an oncoprotein with established roles in leukemia and solid tumor progression. It is normally expressed in brain and sympathetic neurons and has been postulated to play a part in neural differentiation. However, no role for AF1q in tumors of neural origin has been reported. In this study, we found AF1q to be a universal marker of neuroblastoma tumors. Silencing AF1q in neuroblastoma cells caused proteasomal degradation of N-Myc through Ras/ERK and AKT/GSK3β pathways, activated p53 and blocked cell cycle progression, culminating in cell death via the intrinsic apoptotic pathway. Moreover, silencing AF1q attenuated neuroblastoma tumorigenicity in vivo signifying AF1q’s importance in neuroblastoma oncogenesis. Our findings reveal AF1q to be a novel regulator of N-Myc and potential therapeutic target in neuroblastoma. Funding This work was supported by the Swim Across America Foundation, the Go4theGoal Foundation, the John and Edna Beck Chair in Pediatric Cancer Research (JDS), a grant from the St. Baldrick’s Foundation (AA), and a grant from the V foundation (SA). This study was conducted with resources from the UCSF Benioff Children’s Hospital Oakland Pediatric Tumor Bank, a core facility funded by the St. Baldrick’s and Swim Across America Foundations. https://cassyni-user-files-prod.s3.amazonaws.com/JBWTPwHoJtvmgsnehX4NjG https://cassyni.com/slides/outline/TdXUCcxkzWiuU2sQEgW8iZ https://cassyni.com/events/TdXUCcxkzWiuU2sQEgW8iZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Nf75SVXj7Ro8hwmt9nDcZ4 https://cassyni.com/events/TdXUCcxkzWiuU2sQEgW8iZ?videoPreview=1 Lightweight active back exosuit reduces muscular effort during an hour-long order picking tasknohttps://cassyni.com/events/TdXUCcxkzWiuU2sQEgW8iZ?videoPreview=12024-05-14T09:00:00+00:001632.0Communications EngineeringOccupational back exoskeletons and exosuits aim to reduce low back injuries in the workplace. For these technologies to be adopted, it is important that they provide biomechanical benefits to the wearer and do not disrupt job performance. To address this challenge, here we developed a lightweight, soft, active back exosuit that can autonomously control virtual impedance to apply differing assistance during lowering and lifting. This video highlight reviews some factors that were considered in the development of our soft active back exosuit actuation strategy. Despite noted limitations in our approach, we highlight how these decisions contributed to our results presented in Nature Communications Engineering that demonstrate: In usability tests, participants rated the exosuit as easy to learn and use and reported feeling confident while wearing it. In an experiment involving an hour long order picking task we demonstrated that the exosuit reduced peak and median muscle activations in the back by 18% and 20%, respectively. Despite the complexity of the movements required, such as walking, bending, and navigating around obstacles while lifting boxes from under a rack, our controller demonstrated impressive robustness with only 14 mistriggers out of 9600 lifts (0.1%). Collectively we hope this video review highlights how active exosuit technology can be iterated to provide it the potential to be a highly usable solution to aid warehouse workers in real-world settings.https://cassyni-user-files-prod.s3.amazonaws.com/Nf75SVXj7Ro8hwmt9nDcZ4 https://cassyni.com/events/WbJc2CnN1pLday2r6u7vWh/seminar/qa https://cassyni.com/slides/outline/WbJc2CnN1pLday2r6u7vWh https://cassyni.com/events/WbJc2CnN1pLday2r6u7vWh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/M5mspxWqBCqPK3QTYnZbMY https://cassyni.com/events/WbJc2CnN1pLday2r6u7vWh?videoPreview=1 Unifying mathematics through topos theorynohttps://cassyni.com/events/WbJc2CnN1pLday2r6u7vWh?videoPreview=12023-05-17T14:00:00+00:005015.2Logica UniversalisThe paper "The unification of Mathematics via Topos Theory", written in 2010 and recently published in the book "Logic in Question. Studies in Universal Logic", introduced a set of principles and methodologies for unifying distinct mathematical theories with each other, resulting from a new view of Grothendieck toposes as “bridge” objects for transferring information, ideas, and results between different mathematical contexts. We shall make a survey of the theoretical principles underlying the use of toposes as unifying 'bridges', as well as of the further developments and notable applications of this theory obtained throughout the past years. https://cassyni-user-files-prod.s3.amazonaws.com/M5mspxWqBCqPK3QTYnZbMY https://cassyni.com/slides/outline/X5xD4tRtTGtgajZjhLQin1 https://cassyni.com/events/X5xD4tRtTGtgajZjhLQin1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/38tvuSecbeSxzxVZ7hjBZg https://cassyni.com/events/X5xD4tRtTGtgajZjhLQin1?videoPreview=1 NGS 2022 - Taking the next step in your careernohttps://cassyni.com/events/X5xD4tRtTGtgajZjhLQin1?videoPreview=12022-07-20T08:00:00+00:003721.88New Phytologist Foundation Panel discussion and Q&A – Taking the next step in your career.https://cassyni-user-files-prod.s3.amazonaws.com/38tvuSecbeSxzxVZ7hjBZg https://cassyni.com/slides/outline/PBYvDKZc2b72Gh3kwMS2Bo https://cassyni.com/events/PBYvDKZc2b72Gh3kwMS2Bo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KBa5VxyBSb9S168SAjyKiE https://cassyni.com/events/PBYvDKZc2b72Gh3kwMS2Bo?videoPreview=1 Machine Learning for Fluid Mechanicsnohttps://cassyni.com/events/PBYvDKZc2b72Gh3kwMS2Bo?videoPreview=12020-11-13T12:00:00+00:001808.28Brunton LabThis video gives an overview of how Machine Learning is being used in Fluid Mechanics. In fact, fluid mechanics is one of the original 'big data' sciences, and many advances in ML came out of fluids.https://cassyni-user-files-prod.s3.amazonaws.com/KBa5VxyBSb9S168SAjyKiE https://cassyni.com/slides/outline/HkRGhoSqCZ1wspoXLSSECM https://cassyni.com/events/HkRGhoSqCZ1wspoXLSSECM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RULKnMCAngXy5V5NWfXvWi https://cassyni.com/events/HkRGhoSqCZ1wspoXLSSECM?videoPreview=1 Deep Reinforcement Learning for Fluid Dynamics and Controlnohttps://cassyni.com/events/HkRGhoSqCZ1wspoXLSSECM?videoPreview=12021-03-05T12:00:00+00:001054.84Brunton LabReinforcement learning based on deep learning is currently being used for impressive control of fluid dynamic systems. This video will describe recent advances, including for mimicking the behavior of birds and fish, for turbulence closure modeling with sub-grid-scale models, and for robotic flight demonstrations.https://cassyni-user-files-prod.s3.amazonaws.com/RULKnMCAngXy5V5NWfXvWi https://cassyni.com/events/W6dNrtcxAzromW3LJnzxLV/seminar/qa https://cassyni.com/slides/outline/W6dNrtcxAzromW3LJnzxLV https://cassyni.com/events/W6dNrtcxAzromW3LJnzxLV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BUyZFQGhddmv3j6WawzwQi https://cassyni.com/events/W6dNrtcxAzromW3LJnzxLV?videoPreview=1 Trust-materiality theory of lending: The evolution of non-market lending through relationship trust and object materiality interplaysnohttps://cassyni.com/events/W6dNrtcxAzromW3LJnzxLV?videoPreview=12023-04-19T02:00:00+00:004110.04Department of MarketingThe purpose of this research is to investigate consumer-object interplays and relationship trust in the context of non-market consumer lending. This research adopts a multi-method qualitative research approach consisting of two stages: a non-participatory netnography followed by unstructured online interviews. A thematic data analysis process was used to discover repeating patterns and concepts. Findings of this research reveal that various material properties of lending objects and the surrounding material environment interplay with relational trust components, and through their fluid interactions they shape three stages of lending: perplexity, clarification, and stabilisation. Moreover, there is a mutually empowering or restraining relationship that exists between materiality and trust components, and through their interplays, a range of lending outcomes that include conditional, unconditional, and prohibited lending practices emerge.https://cassyni-user-files-prod.s3.amazonaws.com/BUyZFQGhddmv3j6WawzwQi https://cassyni.com/slides/outline/YZsQ6JraNHdJ8SWtrUub4R https://cassyni.com/events/YZsQ6JraNHdJ8SWtrUub4R/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CT8EHdicMHQcDPyas6Y7KC https://cassyni.com/events/YZsQ6JraNHdJ8SWtrUub4R?videoPreview=1 Statistical Aspects of Deep Learningnohttps://cassyni.com/events/YZsQ6JraNHdJ8SWtrUub4R?videoPreview=12023-03-01T17:00:00+00:003872.84Journal of Statistical Theory and PracticeMost of the methodology for Deep Learning (DL) has been built by computer scientists, and they have done an amazing job---DL is changing the world in powerful ways. But computer scientists look at the world differently from statisticians, and I think there is value in both perspectives. This talk describes some of the many contributions statistics can make to DL techniques. https://cassyni-user-files-prod.s3.amazonaws.com/CT8EHdicMHQcDPyas6Y7KC https://cassyni.com/events/RA9LQ49hnRKnNQKzJKHxcM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8CjVTbFPN6mLyyJPPJ3pyt https://cassyni.com/events/TdPMdUPKyi6GjLoYr1CbLH/seminar/qa https://cassyni.com/slides/outline/TdPMdUPKyi6GjLoYr1CbLH https://cassyni.com/events/TdPMdUPKyi6GjLoYr1CbLH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XJYfbGR6uNqY3nE6bPMUFg https://cassyni.com/slides/outline/DoESLLGdgtao6ALqwKrBbT https://cassyni.com/events/DoESLLGdgtao6ALqwKrBbT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/D1yGKNG6SEPSaUzCgR3EwY https://cassyni.com/events/DoESLLGdgtao6ALqwKrBbT?videoPreview=1 Anthromes, CO2 and Terrestrial Carbon – Session 8: Net-zero, carbon as capital, and land justice: Avoiding the great carbon land grabnohttps://cassyni.com/events/DoESLLGdgtao6ALqwKrBbT?videoPreview=12023-03-30T12:30:00+00:006455.44The New Phytologist Foundation8.30 – 8.35: Welcome to the day 8.35 – 8.55: Collective Property Rights Lead to Secondary Forest Growth in the Brazilian Amazon, Kathryn Baragwanath 8.55 – 9.15: The mismeasure of terrestrial carbon policy: How many current policies are unjust and ineffective and how to fix it, Forrest Fleischman 9.15 – 9.35: Engaging stakeholders to develop inclusive and just net-zero solutions, Keith Kline 9.35 – 9.55: Terrestrial carbon removal activities, standards, certifications, and their expected durations, Starry Sprenkle-Hoppolite 9.55 – 10.15: Forested anthromes: providing an opportunity for net-zero goals through sustainable management, Maggie Davis https://cassyni-user-files-prod.s3.amazonaws.com/D1yGKNG6SEPSaUzCgR3EwY https://cassyni.com/slides/outline/ALhD1YjxcgiA4U3HHfUE4d https://cassyni.com/events/ALhD1YjxcgiA4U3HHfUE4d/abstract https://cassyni-user-files-prod.s3.amazonaws.com/M316RXeQ64DoGnz75WQJFg https://cassyni.com/events/ALhD1YjxcgiA4U3HHfUE4d?videoPreview=1 Bioinspired Soft Robotics for Sustainabilitynohttps://cassyni.com/events/ALhD1YjxcgiA4U3HHfUE4d?videoPreview=12023-04-13T10:00:00+00:004849.0Mechanical EngineeringThe advancement of technology has a profound and far-reaching impact on society, currently penetrating all areas of life. This advance, however, often negatively affects our ecosystems, with growing demands on energy, contributions to greenhouse gas emissions, and environmental pollution. Mitigating these adverse effects is among the grand challenges of our times and provides a strong motivation to push the research frontier on materials and robotics. A new wave of eco-friendly robots is envisioned by merging bioinspired soft robotics, material science, nanocomposite technologies, and environmental science. Taking inspiration from natural systems can provide new insights for designing the next generation robots and rethinking robot bodies, control, and interactions with humans/world over their entire life (i.e., a robotics life cycle). These “green robots” will operate in unstructured environments for environmental monitoring, precision agriculture, reforestation, biodiversity protection, and remediation. With this vision in mind, this talk will present some of our results on plant- and soft animal-inspired robots with high morphological adaptability, distributed sensory systems, as well as energy-saving mechanisms, which are able to operate in natural habitats while minimizing waste and reducing their environmental footprint.https://cassyni-user-files-prod.s3.amazonaws.com/M316RXeQ64DoGnz75WQJFg https://cassyni.com/events/CowEExyaoyUeRQWqqMNrnZ/seminar/qa https://cassyni.com/slides/outline/CowEExyaoyUeRQWqqMNrnZ https://cassyni.com/events/CowEExyaoyUeRQWqqMNrnZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/YQA4doctY1eSF7ZVLSS7ie https://cassyni.com/events/CowEExyaoyUeRQWqqMNrnZ?videoPreview=1 Importance of Spectral Properties of Viscous Flux Discretization and Gradient-Based Reconstruction Approachnohttps://cassyni.com/events/CowEExyaoyUeRQWqqMNrnZ?videoPreview=12023-04-23T12:00:00+00:003530.24Cassyni SeminarsIn this talk, I present the importance of viscous flux discretization for a wide variety of flows and the novel gradient-based reconstruction approach. First, I will present our observations regarding viscous flux discretization. While investigating nonlinear instability encountered in a high-resolution viscous shock-tube simulation, we have discovered that using an appropriate viscous scheme is important in preventing spurious oscillations around shocks. The existing viscous scheme of Shen and Zha and $\alpha$-damping scheme are used for the simulations. Even though both schemes are sixth-order accurate, the $\alpha$-damping approach gave superior results and is free of oscillations. The main difference between both schemes is in the spectral properties. It was concluded that having good spectral properties (high-frequency damping) is essential. We extended this idea further to turbulent shock-free flows, where we studied six different methods, divided into two classes, with poor and better representation of spectral properties at high wavenumbers. Both theoretical and numerical results have revealed that the method with better properties at high wavenumbers, denoted as $\alpha$-damping type discretization, produced superior solutions compared to the other methods for the viscous Taylor-Green vortex test case. Second, I will present the Gradient-Based Reconstruction (GBR) approach for the convective fluxes. The original idea was to compute the gradients once and re-use them in both viscous and inviscid fluxes, and the importance of viscous fluxes was an observation. GBR is a novel approach for computing the cell interface values using gradients. Problem-independent shock-capturing techniques are considered, and the results for the benchmark cases are presented. It is observed that the proposed methods produced significantly better results than the existing methods. Furthermore, the GBR approach is efficient as the gradients are shared between several subroutines. Even for convective fluxes, the spectral properties might be more important than the order of accuracy alone. Finally, I will briefly present various applications where these methods are used.https://cassyni-user-files-prod.s3.amazonaws.com/YQA4doctY1eSF7ZVLSS7ie https://cassyni.com/slides/outline/LDgv3rCLoCiD4Tji5oB2qB https://cassyni.com/events/LDgv3rCLoCiD4Tji5oB2qB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FxiJERos6SmiNUFp1Nczce https://cassyni.com/events/LDgv3rCLoCiD4Tji5oB2qB?videoPreview=1 Plant Variety Rights in New Zealand: Then and Nownohttps://cassyni.com/events/LDgv3rCLoCiD4Tji5oB2qB?videoPreview=12023-08-15T01:00:00+00:005221.84SACLThis seminar will discuss the changes adopted in the recent overhaul of the plant variety rights system and how they may operate once the law is fully implemented. In addition to discussing the likely impact of the new Act on plant breeding and the New Zealand economy, the seminar will consider the Act’s recognition and respect for the Crown’s obligations under the principles of Te Tiriti o Waitangi | the Treaty of Waitangi, particularly in relation to the realisation of tino rangatiratanga. The discussion is based on recent research involving both doctrinal analysis of the PVR Act and an intellectual property landscape analysis. This latter methodology reveals how plant variety rights systems, both within Aotearoa and overseas, have been used by entities without Māori ancestry to assert ownership claims to varieties of taonga plants in the past. The seminar will explore how some of the changes made in the PVR Act support the exercise of partial Māori authority in relation to taonga, and the limitations on realising tino rangatiratanga via the New Zealand plant variety rights system.https://cassyni-user-files-prod.s3.amazonaws.com/FxiJERos6SmiNUFp1Nczce https://cassyni.com/events/T3xHscQ7ofi2BZfAe7dND/seminar/qa https://cassyni.com/slides/outline/T3xHscQ7ofi2BZfAe7dND https://cassyni.com/events/T3xHscQ7ofi2BZfAe7dND/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DMMBhy3H7eiPs8Fwf5LCjQ https://cassyni.com/events/T3xHscQ7ofi2BZfAe7dND?videoPreview=1 Detecting and attributing the causes of biodiversity change: needs, gaps and solutionsnohttps://cassyni.com/events/T3xHscQ7ofi2BZfAe7dND?videoPreview=12023-07-13T14:00:00+00:003348.36Royal Society PublishingA recent theme issue of *Phil Trans B* addressed the multifaceted problems of tracking biodiversity change to meet emerging international development goals, national economic accounting, and diverse community interests. The results place biodiversity science in the context of policy needs, and provide an updated roadmap for how to acquire, process, and use biodiversity observation data in a changing world. In this seminar, several of the authors will speak about their work. https://cassyni-user-files-prod.s3.amazonaws.com/DMMBhy3H7eiPs8Fwf5LCjQ https://cassyni.com/events/JF87yk88SjRYXHqWJ3zhWd/seminar/qa https://cassyni.com/slides/outline/JF87yk88SjRYXHqWJ3zhWd https://cassyni.com/events/JF87yk88SjRYXHqWJ3zhWd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8YrMCeUWkqgVDxVEpqZdz6 https://cassyni.com/events/JF87yk88SjRYXHqWJ3zhWd?videoPreview=1 Diversity, Equity & Inclusion: Why It Matters in Publishingnohttps://cassyni.com/events/JF87yk88SjRYXHqWJ3zhWd?videoPreview=12023-09-26T14:00:00+00:002656.28Topics at the heart of our communityAt Springer Nature, we continue to champion considerations of Diversity, Equity & Inclusion (DEI) not only within our own organization, but within the research communities we serve worldwide. We aspire to build inclusive publishing practices working with diverse networks of researchers – editors, authors & reviewers - to advance diversity, equity and inclusion. Sowmya Swaminathan - Director, External DEI - sheds light on what you can do to uphold and amplify inclusive publishing practices in your journal and in your work as editors. She will also introduce you to resources developed at Springer Nature to support your efforts.https://cassyni-user-files-prod.s3.amazonaws.com/8YrMCeUWkqgVDxVEpqZdz6 https://cassyni.com/slides/outline/XadSECbJJ6NWQW96TH92BP https://cassyni.com/events/XadSECbJJ6NWQW96TH92BP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HPZ3zW3JX34k7wp5TyqzSr https://cassyni.com/events/XadSECbJJ6NWQW96TH92BP?videoPreview=1 Rethinking How We Build Compilers: Synthesis and Neural Machine Translationnohttps://cassyni.com/events/XadSECbJJ6NWQW96TH92BP?videoPreview=12023-09-11T16:00:00+00:001980.04HiPEDS CentreMoore’s Law has been the main driver behind the extraordinary success of computer systems. However, with the technology roadmap showing a decline in transistor scaling, computer systems are increasingly heterogeneous, specialised and diverse. As it stands, software will simply not fit and current compiler technology is struggling to bridge the gap. We need to fundamentally rethink the role and design of the compiler. This talk presents two novel approaches to this problem. The first uses program synthesis to lift programs to MLIR, an emerging infrastructure for building high-level compilers, that can effectively target modern hardware. The second uses neural machine translation to compiler and decompile code. which outperforms the state of the art.https://cassyni-user-files-prod.s3.amazonaws.com/HPZ3zW3JX34k7wp5TyqzSr https://cassyni.com/events/wjBTBmoxd9Xqx91vaqvmb/seminar/qa https://cassyni.com/slides/outline/wjBTBmoxd9Xqx91vaqvmb https://cassyni.com/events/wjBTBmoxd9Xqx91vaqvmb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9id3LTgEJCqRYwgL1xJFQS https://cassyni.com/events/wjBTBmoxd9Xqx91vaqvmb?videoPreview=1 Direct nanofiltration for drinking water and wastewater treatmentnohttps://cassyni.com/events/wjBTBmoxd9Xqx91vaqvmb?videoPreview=12023-10-24T08:00:00+00:003553.32ElsevierWater treatment using a nanofiltration (NF) membrane is an effective advanced water treatment process for achieving high organics removal. This presentation will cover our recent studies examining the feasibility of direct (i.e., no pre-treatment) NF treatment of surface water and wastewater using a submerged flat-sheet NF membrane module. When a direct NF system was employed for surface water treatment, we observed only slight membrane fouling over three months. The separation performance of the NF system remained high: total organic carbon (TOC) removal remained at 80-90% in most sampling occasions. Membrane surface characterization revealed that many substances covered the membrane surface. It was speculated that these substances deposited on the membrane surface provide a small contribution to the hydraulic resistance. Further, the membrane foulant was readily removed by physical cleaning, and the permeability fully recovered. This indicates that the membrane foulant did not penetrate the pores of the NF membrane. The results attained through the on-site test suggest the viability of direct NF treatment of surface water for achieving high water quality and stable system operation. In addition to the drinking water treatment, the presentation will provide the results of applying the direct NF system for wastewater treatment. https://cassyni-user-files-prod.s3.amazonaws.com/9id3LTgEJCqRYwgL1xJFQS https://cassyni.com/events/QAvzeaQK7azSjd5Fh57TgH/seminar/qa https://cassyni.com/slides/outline/QAvzeaQK7azSjd5Fh57TgH https://cassyni.com/events/QAvzeaQK7azSjd5Fh57TgH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5yBtu8NyPsqwtyywPnDybU https://cassyni.com/events/QAvzeaQK7azSjd5Fh57TgH?videoPreview=1 GAN fingerprint for active detection/attribution of fake medianohttps://cassyni.com/events/QAvzeaQK7azSjd5Fh57TgH?videoPreview=12023-11-02T11:30:00+00:003210.24Journal on Image and Video ProcessingThe continuous progress of generative models is fostering impressive advances in a variety of applications ranging from videoconferencing through virtual reality, passing from fast and seamingless creation of personalized media. At the same time, the availability of increasingly powerful tools for the generation of synthetic contents raises concerns about the possibility of distinguishing synthetic and genuine contents. Possible misuses of generative models, in fact, include the creation of fake media to support misinformation campaigns, defamation, polarization of public opinion and so on. For this reason, several multimedia forensic techniques have been developed to distinguish fake and real contents and trace back the manipulation history of any piece of media. However, such techniques fall short of keeping the pace of technological advancements, in addition they are not suitable to be applied in the wild even because they rely on subtle traces that are usually washed away by common processing tools (e.g. lossy compression). In this talk, I will advocate the use of active forensics techniques relying on the introduction within the to-be-authenticated content of a unique fingerprint (a.k.a. watermark). The fingerprint should be introduced within the media at creation time and should not be possible to remove it without degrading the hosting content in a significant way. In contrast to classical watermarking, here the fingerprint is embedded within the generative model, rather than directly in the generated content. In fact, to retain its effectiveness the generative models should still introduce a detectable fingerprint also in the presence of model finetuning, pruning and compression. In this webinar, I will outline the main challenges and opportunities associated to generative model fingerprinting and and describe some recent works of mine in this field.https://cassyni-user-files-prod.s3.amazonaws.com/5yBtu8NyPsqwtyywPnDybU https://cassyni.com/events/7sY4823zdUiS4HNmKbxgwF/seminar/qa https://cassyni.com/slides/outline/7sY4823zdUiS4HNmKbxgwF https://cassyni.com/events/7sY4823zdUiS4HNmKbxgwF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9M1ZWQWKEtEcCUDxpQTLrz https://cassyni.com/events/7sY4823zdUiS4HNmKbxgwF?videoPreview=1 Momentum Conservation in Biological Communication: Its not about the moleculesnohttps://cassyni.com/events/7sY4823zdUiS4HNmKbxgwF?videoPreview=12023-11-16T15:00:00+00:004151.88Journal of Biological PhysicsLife is full of hydrated interfaces that all must obey physical principles. Neglecting conservation laws (unintentionally or not) is no misdemeanor but a serious violation of nature’s principles and can lead to an absurd picture of nature. I here present, what (biological) interfaces naturally “produce” once “fed” with momentum conservation and the 2nd law of thermodynamics. Data show the existence of linear and nonlinear pulses, which are capable to trigger and suppress enzymatic activity. Together with the 2nd law, momentum conservation allows to control biological processes from remote. Specificity of this control also arises from physics and is found in the phase diagrams of this interfaces near transitions (state-function relation). Together this leads to a physical perspective for the origin of biological communication and a concept for the integration of physical principles and biochemical reactions. https://cassyni-user-files-prod.s3.amazonaws.com/9M1ZWQWKEtEcCUDxpQTLrz https://cassyni.com/events/HFtA7drrNYAko3srw1coQR/seminar/qa https://cassyni.com/slides/outline/HFtA7drrNYAko3srw1coQR https://cassyni.com/events/HFtA7drrNYAko3srw1coQR/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6sE91ycUF5Et6QZ5xaDb7k https://cassyni.com/events/HFtA7drrNYAko3srw1coQR?videoPreview=1 The Great Renal Debate: "The patient perspective needs greater prominence in dialysis care", Summing up and thanksnohttps://cassyni.com/events/HFtA7drrNYAko3srw1coQR?videoPreview=12024-03-15T16:00:00+00:003639.36Imperial College Renal and Transplant CentreOur traditional annual Clash of Titans! We will have a lively debate... For: Prof Jeremy Levy Against: Dr Damien Ashby Join the fun! A rapid review of what we have learned and opportunity to thank the faculty and delegates https://cassyni-user-files-prod.s3.amazonaws.com/6sE91ycUF5Et6QZ5xaDb7k https://cassyni.com/slides/outline/RepZZNK7dEocBsKW6RQvnZ https://cassyni.com/events/RepZZNK7dEocBsKW6RQvnZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RV5bzEZYPbu2A4fhHp11pA https://cassyni.com/events/RepZZNK7dEocBsKW6RQvnZ?videoPreview=1 The person-to-person transmission landscape of the gut and oral microbiomesnohttps://cassyni.com/events/RepZZNK7dEocBsKW6RQvnZ?videoPreview=12023-05-10T13:00:00+00:001082.88Cassyni SeminarsThe human microbiome is an integral component of the human body and a co-determinant of several health conditions. However, the extent to which interpersonal relations shape the individual genetic makeup of the microbiome and its transmission within and across populations remains largely unknown. Here, capitalizing on more than 9,700 human metagenomes and computational strain-level profiling, we detected extensive bacterial strain sharing across individuals (more than 10 million instances) with distinct mother-to-infant, intra-household and intra-population transmission patterns. Mother-to-infant gut microbiome transmission was considerable and stable during infancy (around 50% of the same strains among shared species (strain-sharing rate)) and remained detectable at older ages. By contrast, the transmission of the oral microbiome occurred largely horizontally and was enhanced by the duration of cohabitation. There was substantial strain sharing among cohabiting individuals, with 12% and 32% median strain-sharing rates for the gut and oral microbiomes, and time since cohabitation affected strain sharing more than age or genetics did. Bacterial strain sharing additionally recapitulated host population structures better than species-level profiles did. Finally, distinct taxa appeared as efficient spreaders across transmission modes and were associated with different predicted bacterial phenotypes linked with out-of-host survival capabilities. The extent of microorganism transmission that we describe underscores its relevance in human microbiome studies, especially those on non-infectious, microbiome-associated diseases.https://cassyni-user-files-prod.s3.amazonaws.com/RV5bzEZYPbu2A4fhHp11pA https://cassyni.com/slides/outline/8rn1z8KGhfyDnDkZiojFpH https://cassyni.com/events/8rn1z8KGhfyDnDkZiojFpH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XyqLN1oSRHyjR49bSCzMC https://cassyni.com/events/8rn1z8KGhfyDnDkZiojFpH?videoPreview=1 Interactive fiber-based materials for human-machine interfaces and the tactile internetnohttps://cassyni.com/events/8rn1z8KGhfyDnDkZiojFpH?videoPreview=12023-06-30T00:00:00+00:003588.8The Auckland Bioengineering InstituteThe emerging fields of switchable soft robotics and smart textiles have the potential to revolutionize the tactile internet by enabling the development of novel materials and systems that are capable of self-adaptation, sensing, and actuation. Interactive fiber rubber composites (I-FRC), are fiber-reinforced elastomer materials that are equipped with structurally integrated actuator and sensor networks. This innovative approach allows for the direct integration of actuators and sensors during the manufacturing process, resulting in a more robust and adaptable material. The development of I-FRC will enable the reversible and contactless adjustment of mechanical components, leading to a range of potential applications across various fields including soft robotics for human-machine interaction and prosthetics. Smart textiles, on the other hand, offer a promising solution to facilitate the interaction between humans and machines in the tactile internet. These textiles can transduce motion and sense from and to the body, enabling the development of wearable devices that can adapt to the user's needs and environment. With their ability to detect and respond to environmental changes, smart textiles have the potential to improve the safety, comfort, and efficiency of various applications such as healthcare, sports, and entertainment. These scenarios include smart gloves or e-skins for remote teaching and rehabilitation. The integration of I-FRC and smart textiles holds immense potential for the development of novel systems that are more robust, adaptable, and responsive to changing environments. The synergy between these two fields can facilitate the development of innovative materials and devices that can enhance the user experience and improve the functionality of various applications. Therefore, the exploration and development of these fields are discussed and how they further advance the tactile internet and its applications. #### Acknowledgements This research was funded by the DFG (German Research Foundation), Project Number 380321452-GRK2430 and as part of Germany’s Excellence Strategy – EXC 2050/1 – Project ID 390696704 – Cluster of Excellence “Centre for Tactile Internet with Human-in-the-Loop” (CeTI) of Technische Universität Dresden. https://cassyni-user-files-prod.s3.amazonaws.com/XyqLN1oSRHyjR49bSCzMC https://cassyni.com/slides/outline/BL23DYYttxk2shZggCszW9 https://cassyni.com/events/BL23DYYttxk2shZggCszW9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/H7XJXH9S7N9n3CEiet4xN https://cassyni.com/events/BL23DYYttxk2shZggCszW9?videoPreview=1 Secular orbital dynamics of the innermost exoplanet of the upsilon-Andromedae system in the framework of a quasi-periodic restricted modelnohttps://cassyni.com/events/BL23DYYttxk2shZggCszW9?videoPreview=12022-09-09T12:35:00+00:00857.96Celestial Mechanics and Dynamical AstronomyWe introduce a quasi-periodic restricted Hamiltonian to describe the secular motion of a small-mass planet in a multi-planetary system. In particular, we refer to the motion of upsilon-And b which is the innermost planet among those discovered in the extrasolar system orbiting around the upsilon-Andromedae A star. We preassign the orbits of the Super-Jupiter exoplanets upsilon-And c and upsilon-And d in a stable configuration. The Fourier decompositions of their secular motions are reconstructed by using the well known technique of the (so called) frequency analysis and are injected in the equations describing the orbital dynamics of upsilon-And b under the gravitational effects exerted by those two external exoplanets (that are expected to be major ones in such an extrasolar system). Therefore, we end up with an Hamiltonian model having 2+3/2 degrees of freedom; its validity is confirmed by the comparison with several numerical integrations of the complete 4-body problem. Furthermore, the model is enriched by taking into account also the effects due to the relativistic correction on the secular motion of the innermost exoplanet. We focus on the problem of the stability of upsilon-And b as a function of the parameters that mostly impact on its orbit, that are the initial values of its inclination and the longitude of its node (as they are measured with respect to the plane of the sky). In particular, we study the evolution of its eccentricity, which is crucial to exclude orbital configurations with high probability of (quasi)collision with the central star in the long-time evolution of the system. Moreover, we also introduce a normal form approach, that is based on the complete average of our restricted model with respect to the angles describing the secular motions of the major exoplanets. Therefore, our Hamiltonian model is further reduced to a system with 2 degrees of freedom. This allows us to very quickly preselect the domains of stability for upsilon-And b, with respect to the set of the initial orbital configurations that are compatible with the observations. This work is made in joint collaboration with U.Locatellihttps://cassyni-user-files-prod.s3.amazonaws.com/H7XJXH9S7N9n3CEiet4xN https://cassyni.com/slides/outline/V7PQznMg6oc23ZfXubEPTT https://cassyni.com/events/V7PQznMg6oc23ZfXubEPTT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FXu3RFoPMjbRJCPEJGHFiE https://cassyni.com/events/V7PQznMg6oc23ZfXubEPTT?videoPreview=1 Heterarchy in Granular Matternohttps://cassyni.com/events/V7PQznMg6oc23ZfXubEPTT?videoPreview=12021-02-11T12:00:00+00:002693.04Granular MatterThis presentation will deal with 'grainsize dynamics' -- the mechanics dealing with the evolution of particle size distributions in space and time, and their governing forces. Typical forces include mixing, segregation and comminution. Considering the particle-scale stochastic processes that govern these dynamics, the scientific aim is to frame equivalent homogenised continua that can handle those processes even when acting simultaneously. A key observation is that mixing and segregation are 'open-system' mechanisms that do not lend themselves for hierarchical approach that artificially identifies scales and treat them separately. On the other hand grain crushing may occur even in 'closed-system', yet its description requires to preserve the state of nonlocal grainsize fabric. We therefore propose a heterarchical multi-scale approach that does not separate scales, and retain both local and nonlocal grainsize information. Although the talk will focus on particle size, much of the presented philosophy may be adapted for other shape descriptors such as elongation and sphericity.https://cassyni-user-files-prod.s3.amazonaws.com/FXu3RFoPMjbRJCPEJGHFiE https://cassyni.com/slides/outline/U86CuR4dDtVsNoqXocm4eZ https://cassyni.com/events/U86CuR4dDtVsNoqXocm4eZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LJ5HaqgrLEfxqHpHExG5Ci https://cassyni.com/events/U86CuR4dDtVsNoqXocm4eZ?videoPreview=1 Self-supervised learning for robotic bin-pickingnohttps://cassyni.com/events/U86CuR4dDtVsNoqXocm4eZ?videoPreview=12023-07-06T10:30:00+00:003409.4Journal on Image and Video ProcessingEndowing robots with human-like dexterity is a longstanding challenge in AI and robotics. State of the art research on robot manipulation is data driven through robot learning but robot data is particularly expensive to acquire. In this talk, I will showcase how robot learning for manipulation can be achieved through self-supervised learning using simulation empowered self-play.https://cassyni-user-files-prod.s3.amazonaws.com/LJ5HaqgrLEfxqHpHExG5Ci https://cassyni.com/slides/outline/6tDDv2F4MCgZF3rMw4YvVj https://cassyni.com/events/6tDDv2F4MCgZF3rMw4YvVj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DzixuEeFXZquUo8HzaZNBx https://cassyni.com/events/6tDDv2F4MCgZF3rMw4YvVj?videoPreview=1 Learning coalitions: how AI and experts can improve their collective decisions from imagesnohttps://cassyni.com/events/6tDDv2F4MCgZF3rMw4YvVj?videoPreview=12022-12-01T12:30:00+00:003276.72Journal on Image and Video ProcessingDeep learning technologies have enabled the development of artificial intelligence systems for the recognition of anomalies in images or for predicting possible effects on the imaged object. For the application to medicine, we propose a new approach to learning and continuous improvement of models, based on a coalition of heterogeneous hospitals sharing the same care methods and continuously improving decisions in a common way to achieve the same quality of clinical decisions for all. The models developed and the humans constitute a learning coalition and the progresses in the quality of the decisions made by the models and by the human experts are quantified in the respect of ethical rules adopted by the coalition.https://cassyni-user-files-prod.s3.amazonaws.com/DzixuEeFXZquUo8HzaZNBx https://cassyni.com/slides/outline/7NrpxhtanfEcEpPFXVqim3 https://cassyni.com/events/7NrpxhtanfEcEpPFXVqim3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5UYHrSjSxRHoYmvby99imc https://cassyni.com/events/7NrpxhtanfEcEpPFXVqim3?videoPreview=1 Recent Issues in Real-World Image Restoration Using Deep Convolutional Neural Networksnohttps://cassyni.com/events/7NrpxhtanfEcEpPFXVqim3?videoPreview=12021-01-07T12:30:00+00:003266.48Journal on Image and Video ProcessingNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/5UYHrSjSxRHoYmvby99imc https://cassyni.com/slides/outline/EHwHcGwvw4zPjdNptwQeuj https://cassyni.com/events/EHwHcGwvw4zPjdNptwQeuj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/YGAXZWEaubMh61NLnG4Q86 https://cassyni.com/events/EHwHcGwvw4zPjdNptwQeuj?videoPreview=1 On Hitchin-Thorpe inequality for four-dimensional compact Ricci solitonsnohttps://cassyni.com/events/EHwHcGwvw4zPjdNptwQeuj?videoPreview=12023-09-07T15:00:00+00:003587.04Journal of Mathematical SciencesIn this talk, we will discuss the geometry of 4-dimensional compact gradient Ricci solitons. We will show that, under an upper bound condition on the range of the potential function, a 4-dimensional compact gradient Ricci soliton must satisfy the classical Hitchin-Thorpe inequality. In addition, some volume estimates will be presented. In particular, we discuss some related open problems. This is a joint work with Xu Cheng and Detang Zhou. https://cassyni-user-files-prod.s3.amazonaws.com/YGAXZWEaubMh61NLnG4Q86 https://cassyni.com/slides/outline/GmBJqhBZ8Mkt6ZrPSdKHdf https://cassyni.com/events/GmBJqhBZ8Mkt6ZrPSdKHdf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/W7XbSipjVf5hbAJ7MsZrhC https://cassyni.com/events/GmBJqhBZ8Mkt6ZrPSdKHdf?videoPreview=1 Welcome to Nature Mental Health: an Introduction for Researchers, Librarians and Information Managersnohttps://cassyni.com/events/GmBJqhBZ8Mkt6ZrPSdKHdf?videoPreview=12022-10-10T11:00:00+00:003528.48Nature Mental HealthIn this webinar, Chief Editor of Nature Mental Health Rebecca Cooney PhD is joined by guest panelists Sara A. Howard MLIS, Librarian for Gender & Sexuality Studies and Student Engagement at Princeton University Library, and Carrie Wade MLIS, Research & Instruction Librarian at Harvard Countway Library. The panel discusses the roles that journals and libraries play in the worldwide mental health community and some specific efforts to advance support and equity for students and researchers. This webinar is designed to be an engaging discussion for librarians, editors, researchers, and information managers across the university and corporate sectors.https://cassyni-user-files-prod.s3.amazonaws.com/W7XbSipjVf5hbAJ7MsZrhC https://cassyni.com/slides/outline/5tyG3uynH1RmWotia2B2PX https://cassyni.com/events/5tyG3uynH1RmWotia2B2PX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2FatrvyaAFdEuMyZLEVvYN https://cassyni.com/events/5tyG3uynH1RmWotia2B2PX?videoPreview=1 The Impact of the Changing Research Landscape on Our Journalsnohttps://cassyni.com/events/5tyG3uynH1RmWotia2B2PX?videoPreview=12024-02-29T15:00:00+00:003353.6Topics at the heart of our communityIn an evermore-crowded journals landscape - which has nearly doubled in size since 2000 - gaining recognition continues to be a challenge for all our editors in attracting high-quality submissions from potential authors. Traditional mechanisms for prospective authors submitting their papers are less successful thanks to a change in researcher behaviour. Join Ritu Dhand, Springer Nature’s Chief Scientific Officer, as she explores key changes in the research publishing landscape over the last decade, and new editorial strategies for how journals can successfully compete to attract high-quality research papers.https://cassyni-user-files-prod.s3.amazonaws.com/2FatrvyaAFdEuMyZLEVvYN https://cassyni.com/events/2SS2j8T7CoZ8V7b9vMo4rh/seminar/qa https://cassyni.com/slides/outline/2SS2j8T7CoZ8V7b9vMo4rh https://cassyni.com/events/2SS2j8T7CoZ8V7b9vMo4rh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3hY1wkZ6myqPAhYMimzhAn https://cassyni.com/events/2SS2j8T7CoZ8V7b9vMo4rh?videoPreview=1 Adoption of AI for Precision Medicinenohttps://cassyni.com/events/2SS2j8T7CoZ8V7b9vMo4rh?videoPreview=12024-01-31T14:00:00+00:003768.12Cambridge PrismsScope: * Broad domain of AI for Precision Medicine * Causality and what it means for the application of AI to Precision Medicine * Bias and fairness in AI training with specific disease examples * NHS data access and barriers to adoption including regulatory environmenthttps://cassyni-user-files-prod.s3.amazonaws.com/3hY1wkZ6myqPAhYMimzhAn https://cassyni.com/slides/outline/9MTF9SUgYVTNLXfUtThfBb https://cassyni.com/events/9MTF9SUgYVTNLXfUtThfBb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WBzYPv9UofEzcmd8F3NUbx https://cassyni.com/events/9MTF9SUgYVTNLXfUtThfBb?videoPreview=1 Management of chordoma and chondrosarcoma with definitive dose-escalated single-fraction spine stereotactic radiosurgerynohttps://cassyni.com/events/9MTF9SUgYVTNLXfUtThfBb?videoPreview=12023-10-16T20:00:00+00:001673.2Journal of Neuro-OncologyJoin Journal of Neuro-Oncology Editory and Chief, Dr. Jason Sheehan, and Associate Editor, Dr. Randy D'Amico, for a conversation with Dr. Amol Ghia and Dr. Claudio Tatsui from MD Anderson Cancer Center to discuss their latest publication on the management of chordoma and chondrosarcoma with definitive dose-escalated single-fraction spine stereotactic radiosurgery.https://cassyni-user-files-prod.s3.amazonaws.com/WBzYPv9UofEzcmd8F3NUbx https://cassyni.com/slides/outline/BphGNriJjnDrhU93S9cHuX https://cassyni.com/events/BphGNriJjnDrhU93S9cHuX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WZUkBRt88kf4sWbTdCFsWe https://cassyni.com/events/BphGNriJjnDrhU93S9cHuX?videoPreview=1 Impact of timing of antiseizure medication withdrawal on seizure recurrence in glioma patients: a retrospective observational studynohttps://cassyni.com/events/BphGNriJjnDrhU93S9cHuX?videoPreview=12023-11-20T21:00:00+00:001408.68Journal of Neuro-OncologyJoin the Journal of Neuro-Oncology's Editor-In-Cheif, Dr. Jason Sheehan, and Associate Editor, Dr. Randy D'Amico, for a discussion with Dr. Pim van der Meer on his latest publication on the impact of timing of antiseizure medication withdrawal on seizure recurrence in glioma patients.https://cassyni-user-files-prod.s3.amazonaws.com/WZUkBRt88kf4sWbTdCFsWe https://cassyni.com/slides/outline/JjoM94HYHYuNLkq26A7fgq https://cassyni.com/events/JjoM94HYHYuNLkq26A7fgq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DWcsN3ucsgwYFUHKBxDmV8 https://cassyni.com/events/JjoM94HYHYuNLkq26A7fgq?videoPreview=1 Introducing Transformative Plant Biotechnology: Can biotechnology contribute to biofortificationnohttps://cassyni.com/events/JjoM94HYHYuNLkq26A7fgq?videoPreview=12023-09-20T13:10:00+00:001977.8The New Phytologist FoundationThe challenge of achieving global food security has matured to include nutritional security, as scientists have realised that not only calorie content but also food composition impact our health and well-being, dramatically. It has been accepted for more than 50 years that diets rich in plants, particularly fruit and vegetables, protect health. Yet over this same period diets have declined, with lower fruit and vegetable content replaced by more cheap, sugary, oily processed foods. These dietary shifts are having a marked impact on the incidence of chronic diseases; obesity, metabolic diseases, type2 diabetes and cardiovascular diseases. I hope to illustrate the potential of dietary improvement using biofortified plant-based foods to enhance our health and quality of life and reduce the economic burden on our social- and health-care systems.https://cassyni-user-files-prod.s3.amazonaws.com/DWcsN3ucsgwYFUHKBxDmV8 https://cassyni.com/slides/outline/KESxBjw4j1TRLXMugbQTx9 https://cassyni.com/events/KESxBjw4j1TRLXMugbQTx9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/F7j5mGm5JRjrggVRqx4Ukn https://cassyni.com/events/KESxBjw4j1TRLXMugbQTx9?videoPreview=1 Introducing Transformative Plant Biotechnology: Elucidating the role of beta-1,3-glucanases in tomato fruit developmentnohttps://cassyni.com/events/KESxBjw4j1TRLXMugbQTx9?videoPreview=12023-09-21T16:30:00+00:00741.0The New Phytologist FoundationFruit ripening, although desirable, correlates with softening, enhanced pathogen susceptibility and bruising, causing losses. Thus, delaying ripening-associated softening is a major target in fruit breeding programmes. During the initial stages of fruit development, phloem unloading of essential signalling molecules and sugars is regulated via symplasmic transport through plasmodesmata (PD), while at later ripening stages, the nutrients accumulate via apoplastic transport (Paniagua et al., 2021a). Callose, a cell wall polysaccharide deposited around PD, regulates symplasmic transport. We used immunolocalization to show that callose deposition changed throughout fruit development and may regulate the switch from symplasmic to apoplastic transport. We show structural and mechanical changes in cellulose and callose during ripening by using atomic force microscopy. To manipulate callose, three beta-1,3-glucanase (BG) genes (Solyc080660, Solyc055840, and Solyc016470) were selected based on their expression (Paniagua et al., 2021b). Overexpression of BGs in tomato hairy roots demonstrated callose degrading activity, thereby validating their enzymatic activity. Transient overexpression of BGs in fruits 4 weeks post anthesis showed that changes in callose significantly affect cell wall composition, structure, and mechanics. Thus, callose could be used as a target to develop strategies for tomato fruit improvement by delaying softening. **Co-Authors**: Candelas Paniagua, Naomi Simmons, Lazar Novakovic, Pallavi Kumari, and Yoselin Benitez-Alfonsohttps://cassyni-user-files-prod.s3.amazonaws.com/F7j5mGm5JRjrggVRqx4Ukn https://cassyni.com/slides/outline/UcmS4jE34hyhCGq3bit2pm https://cassyni.com/events/UcmS4jE34hyhCGq3bit2pm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NT4Nn38CMhcQJqQN25y4bY https://cassyni.com/events/UcmS4jE34hyhCGq3bit2pm?videoPreview=1 Fuzzy Logic–based Maximum Power Point Tracking Using Opal RT Real-Time Machine for Solar PV Systemnohttps://cassyni.com/events/UcmS4jE34hyhCGq3bit2pm?videoPreview=12021-07-05T12:00:00+00:001848.64Discover Applied SciencesIn recent years, solar PV energy has attracted substantial interest from the renewable energy communities. However, it suffers from low conversion efficiency. Hence, power output maximization is essential. The maximum power point tracking (MPPT) is used to get the most power out from solar PV, which is to automatically adjust the operating power when conditions of atmosphere changes. In this talk, the fuzzy logic control technique using Opal-RT machine is presented. The effectiveness of fuzzy logic is compared with the perturb and observe algorithm. Results demonstrate that it provides better performance.https://cassyni-user-files-prod.s3.amazonaws.com/NT4Nn38CMhcQJqQN25y4bY https://cassyni.com/slides/outline/5QJ2tbpNSBwwhLuCmv44DK https://cassyni.com/events/5QJ2tbpNSBwwhLuCmv44DK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/H9cy4yRwwMksJmnqstevVU https://cassyni.com/events/5QJ2tbpNSBwwhLuCmv44DK?videoPreview=1 Development and validation of OpenFOAM for safety related reactive flowsnohttps://cassyni.com/events/5QJ2tbpNSBwwhLuCmv44DK?videoPreview=12023-06-16T10:00:00+00:002213.36Leeds Institute for Fluid DynamicsThe presentation will start with an overview of the systematic approach my team has followed since 2008 to develop, validate and apply in-house version of OpenFOAM for safety related reactive flows. For applications related to fire, explosions and/or deflagration to detonation transition (DDT), our activities have spanned across conventional gaseous, liquid, and solid fuels to syngas, hydrogen and lithium-ion batteries. The physical scales of our simulations range from millimetre to hundred meters. As such, we use detailed physics-based models as well as some simplified approaches depending on the scope of the projects and aspiration of the researchers. For model validation, we use a wide range of experimental data from the literature as well as collaborators in both academia and industry.https://cassyni-user-files-prod.s3.amazonaws.com/H9cy4yRwwMksJmnqstevVU https://cassyni.com/events/FHG7pGksDM2GYruEHUpRMF/seminar/qa https://cassyni.com/slides/outline/FHG7pGksDM2GYruEHUpRMF https://cassyni.com/events/FHG7pGksDM2GYruEHUpRMF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/j7eTcNj6YURzR9cyNpEVC https://cassyni.com/events/FHG7pGksDM2GYruEHUpRMF?videoPreview=1 The Ascendance of Thermoplastic Composites: WTFnohttps://cassyni.com/events/FHG7pGksDM2GYruEHUpRMF?videoPreview=12023-11-29T15:30:00+00:003211.44Department of AeronauticsComposites have been around 'forever', engineered composites have been around nearly 100 years and advanced engineered thermoplastic composites have been around almost 50 years, so Why The Fuss? What is making them much more relevant and applicable now?https://cassyni-user-files-prod.s3.amazonaws.com/j7eTcNj6YURzR9cyNpEVC https://cassyni.com/slides/outline/9r8UJke6PJwC9zezgZpdMo https://cassyni.com/events/9r8UJke6PJwC9zezgZpdMo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HgrrMFeGsSNdLfjKGsz7uQ https://cassyni.com/events/9r8UJke6PJwC9zezgZpdMo?videoPreview=1 Epithelial specific splicing regulator proteins as emerging oncogenes in aggressive prostate cancernohttps://cassyni.com/events/9r8UJke6PJwC9zezgZpdMo?videoPreview=12024-05-31T12:00:00+00:003154.12OncogeneProstate cancer progression is connected to the activity of conventional oncogenes and tumour suppressors and driven by circulating steroid hormones. A key issue has been how to identify and care for aggressively developing prostate tumours. Here we discuss how expression of the splicing regulators ESRP1 and ESRP2, and how their role as "masterminds" of epithelial splicing patterns, have been identified as markers of aggressively proliferating prostate primary tumours. We suggest that the origin of prostate cancer within epithelial cells, and the subsequent association of ESRP1 and ESRP2 expression with more aggressive disease progression, identify ESRP1 and ESRP2 as lineage survival oncogenes. To move this field on in the future it will be important to identify the gene expression targets controlled by ESRP1/2 that regulate prostate cancer proliferation. Potential future therapies could be designed to target ESRP1 and ESRP2 protein activity or their regulated splice isoforms in aggressive prostate tumours. Design of these therapies is potentially complicated by the risk of producing a more mesenchymal splicing environment that might promote tumour metastasis.https://cassyni-user-files-prod.s3.amazonaws.com/HgrrMFeGsSNdLfjKGsz7uQ https://cassyni.com/slides/outline/NCNCaUL6m7hnC9bCwVKo8Z https://cassyni.com/events/NCNCaUL6m7hnC9bCwVKo8Z/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PpNdCCfXs3EEZL35fkVm8A https://cassyni.com/events/NCNCaUL6m7hnC9bCwVKo8Z?videoPreview=1 Goldilocks mixing in ocean shear-induced turbulent overturnsnohttps://cassyni.com/events/NCNCaUL6m7hnC9bCwVKo8Z?videoPreview=12020-12-10T12:00:00+00:002900.36Leeds Institute for Fluid DynamicsWe present a new, simple and physically motivated parameterization, based on the ratio of Thorpe and Ozmidov scales, for the irreversible turbulent flux coefficient ΓM=M/ϵ , i.e. the ratio of the irreversible rate M at which the background potential energy increases in a stratified flow due to macroscopic motions to the dissipation rate of turbulent kinetic energy ϵ . Our parameterization covers all three key phases (crucially, in time) of a shear-induced stratified turbulence life cycle: the initial, ‘hot’ growing phase, the intermediate energetically forced phase and the final ‘cold’ fossilization decaying phase. Covering all three phases allows us to highlight the importance of the intermediate one, to which we refer as the ‘Goldilocks’ phase due to its apparently optimal (and so neither too hot nor too cold, but just right) balance, in which energy transfer from background shear to the turbulent mixing is most efficient. The value of ΓM is close to 1/3 during this phase, which we demonstrate appears to be related to an adjustment towards a critical or marginal Richardson number for sustained turbulence ∼0.2--0.25 . Importantly, although buoyancy effects are still significant at leading order for the turbulent dynamics during this intermediate phase, the marginal balance in the flow ensures that the turbulent mixing of the (density) scalar is nevertheless effectively ‘locked’ to the turbulent mixing of momentum. We present supporting evidence for our parameterization through comparison with six oceanographic datasets that span various turbulence generation regimes and a wide range of geographical location and depth. Using these observations, we highlight the significance of parameterizing an inherently variable flux coefficient for capturing the turbulent flux associated with rare energetic, yet fundamentally shear-driven (and so not strongly stratified) overturns that make a disproportionate contribution to the total mixing. We also highlight the importance of representation of young turbulent patches in the parameterization for connecting the small scale physics to larger scale applications of mixing such as ocean circulation and tracer budgets. Shear-induced turbulence is therefore central to irreversible mixing in the world's oceans, apparently even close to the seafloor, and it is critically important to appreciate the inherent time dependence and evolution of mixing events: history matters to mixing. https://cassyni-user-files-prod.s3.amazonaws.com/PpNdCCfXs3EEZL35fkVm8A https://cassyni.com/slides/outline/QfcDotZixQUGZ64mVBERrV https://cassyni.com/events/QfcDotZixQUGZ64mVBERrV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LjKbevsW7vmd79wdV97UDk https://cassyni.com/events/QfcDotZixQUGZ64mVBERrV?videoPreview=1 A Saturation Paradigm of Kelvin-Helmholtz Turbulencenohttps://cassyni.com/events/QfcDotZixQUGZ64mVBERrV?videoPreview=12023-03-30T12:00:00+00:002857.8Leeds Institute for Fluid DynamicsWhile shear flows in laboratory and geo- and astrophysical fluids abound, are often unstable, and have been studied both experimentally and numerically, a reliable understanding of the nonlinear saturation of the instability remains elusive. The common assumption of instability-saturation is that the unstable-mode energy, in its entirety, is cascaded to small scales where it is dissipated. Though the cascade exists, I will show, using novel eigenmode-coupled energy transfer analyses, that in both two- and three-dimensional driven shear-flow turbulence almost all the unstable-mode energy is transferred to large-scale linearly stable modes at the instability scale itself. These stable modes then return the turbulent energy to the background gradient. This finding is consequential also to magnetized turbulence where removing the stable modes of Kelvin-Helmholtz-instability in numerical simulations enhances, by an order of magnitude, both the small-scale cascade and dissipation, including that of magnetic fluctuations. Detailed examination shows that the flow composed of the unstable modes, in stable modes’ absentia, rapidly distorts and folds the magnetic field lines [1]. In the shear layer, up-gradient momentum transport by the stable modes cancels 70%-90% of down-gradient momentum transport by the unstable modes [2]. A model based on only a few unstable and stable modes accurately reproduces the transport rates from full-scale turbulence simulations. With this new instability-saturation paradigm, inroads to old and important problems of shear-driven dynamos and reconnection-driven outflows may be possible.https://cassyni-user-files-prod.s3.amazonaws.com/LjKbevsW7vmd79wdV97UDk https://cassyni.com/events/4ug3xYgjQ6Kcr44iU3hhad/seminar/qa https://cassyni.com/slides/outline/4ug3xYgjQ6Kcr44iU3hhad https://cassyni.com/events/4ug3xYgjQ6Kcr44iU3hhad/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4ZfpmwwGYXobmea2XZxLuL https://cassyni.com/events/4ug3xYgjQ6Kcr44iU3hhad?videoPreview=1 Preventing, declaring and learning from species extinctions: the role of lawnohttps://cassyni.com/events/4ug3xYgjQ6Kcr44iU3hhad?videoPreview=12024-08-15T11:00:00+00:001903.04Cambridge PrismsBiodiversity laws around the world differ, but, at their core, these laws promote the fundamental objective of preventing environmental decline and species extinctions. A variety of legal mechanisms have been implemented in domestic laws around the world to achieve this objective, including protection for habitat, environmental impact assessments and threatened species recovery plans. In many jurisdictions, if these mechanisms fail to protect a species, it may be legally declared extinct, or added to a formal list of those that have been lost. This paper examines the purpose and implications of extinction, from a legal perspective. A legal power to recognise a species as extinct has the potential to foster ambition, transparency and rigorous measurement of progress against conservation goals. However, in practice, efforts to prevent extinction are applied selectively. Without an obligation to learn from extinctions, recognition of species extinctions in law may have perverse effects, or no effect at all. This paper considers how law might play a more productive and positive role in preventing extinctions and improving conservation outcomes.https://cassyni-user-files-prod.s3.amazonaws.com/4ZfpmwwGYXobmea2XZxLuL https://cassyni.com/slides/outline/DJhKkAgersjc1PRBXu2koX https://cassyni.com/events/DJhKkAgersjc1PRBXu2koX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PYuHz3iS8WyM5nAwpfXojt https://cassyni.com/events/DJhKkAgersjc1PRBXu2koX?videoPreview=1 Partially holomorphic functions in several variablesnohttps://cassyni.com/events/DJhKkAgersjc1PRBXu2koX?videoPreview=12023-04-06T15:00:00+00:003249.24Journal of Mathematical SciencesIn this talk we introduce the notion of “partially holomorphic functions” in several variables. Given a domain in ℂ𝑛, we all a function partially holomorphic if it is holomorphic on the slices in one affine direction, while in one or more other affine directions it satisfies moment conditions for being holomorphic. On the ball an example is any polynomial in 𝑧, 𝑤, |𝑤|. Any such function is holomorphic in 𝑧, while on slices where 𝑧 is constant, it extends holomorphically from any circle centered at 0. Partially holomorphic functions on the ball are the main object of study in this talk. They arise naturally when considering functions on the sphere which have holomorphic extensions in multiple affine directions. Other domains are also interesting. The goal of this research was to show that partially holomorphic functions on the ball must be real analytic, given enough directions; we have partial progress on this question.https://cassyni-user-files-prod.s3.amazonaws.com/PYuHz3iS8WyM5nAwpfXojt https://cassyni.com/events/W6mVS3CPBoVSWC7BhUJVim/seminar/qa https://cassyni.com/slides/outline/W6mVS3CPBoVSWC7BhUJVim https://cassyni.com/events/W6mVS3CPBoVSWC7BhUJVim/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TFNQU2nj7EJ4T9n4evbR26 https://cassyni.com/events/W6mVS3CPBoVSWC7BhUJVim?videoPreview=1 The Future of Planetary Defensenohttps://cassyni.com/events/W6mVS3CPBoVSWC7BhUJVim?videoPreview=12024-06-04T16:00:00+00:003681.4AIAA JournalAsteroid impacts pose a credible threat to humanity, but--unlike many types of natural disasters--they are also potentially preventable. Planetary defense encompasses all efforts to detect and warn of potential near-Earth object impacts and to either prevent impacts or reduce their consequences, if impact cannot be prevented. Over the last few years, planetary defense has moved into the mainstream, and planetary-defense efforts have accelerated across the globe. With the success of NASA's Double Asteroid Redirection Test (DART) mission in 2022, humanity has now demonstrated that we have a viable technology to deflect asteroids. But what comes next? This seminar will provide an overview of the hazards posed by near-Earth object impacts, the state of the field, and outline what needs to be done in the coming decade to make progress toward an operational planetary defense capabilityhttps://cassyni-user-files-prod.s3.amazonaws.com/TFNQU2nj7EJ4T9n4evbR26 https://cassyni.com/slides/outline/CKQ7eoPbyxdTLdbBRvZRzd https://cassyni.com/events/CKQ7eoPbyxdTLdbBRvZRzd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/qQr4Rr14Jq38yHFRax96v https://cassyni.com/events/CKQ7eoPbyxdTLdbBRvZRzd?videoPreview=1 Modeling epigenetic lesions that cause gliomasnohttps://cassyni.com/events/CKQ7eoPbyxdTLdbBRvZRzd?videoPreview=12024-01-18T19:00:00+00:003478.76Center for Cancer TrainingDiffuse gliomas are the most common malignant primary brain tumors and remain incurable despite aggressive multimodal therapies. Understanding the mechanisms by which gliomas arise is a critical step towards improved therapies. Missense mutations in the metabolic enzyme Isocitrate Dehydrogenase 1 (IDH1) drive a subtype of diffuse gliomas with genome-wide DNA hypermethylation, termed the G-CIMP hypermethylator profile. This profile is caused by mutant IDH1 (IDH1mut) enzyme, which produces 2-hydroxyglutarate (2-HG), an oncometabolite inhibitor of the ten-eleven translocation (TET) demethylases. DNA hypermethylation may promote gliomagenesis by silencing tumor suppressor genes or, alternatively, by activating proto-oncogenes through disruption of CCCTC-binding factor (CTCF) insulators. CTCF insulator sites define the three-dimensional shape of the genome by dictating the boundaries of topologically associating domains (TADs). Enhancers and promoters can interact when located in the same TAD but are restricted from interacting across different TADs. In IDH1mut gliomas, CpG dinucleotides around CTCF binding sites are frequently methylated, effectively compromising CTCF binding and thus TAD organization. Importantly, the effects of TAD reorganization on gene expression are contingent on enhancers, which are cell-type specific. To determine the epigenetic changes that fuel gliomagenesis, we employed a multi-omic approach on clinical IDH1mut glioma samples, leveraging methylation, transcription factor DNA binding, and gene expression analyses. We found a CTCF insulator near the Platelet-derived Growth Factor Receptor A (PDGFRA) proto-oncogene that is recurrently disrupted by methylation. We demonstrate that disruption of the syntenic insulator in mouse oligodendrocyte progenitor cells (OPCs) allows an OPC-specific enhancer to contact and induce Pdgfra, thereby increasing proliferation. We show that a second lesion, methylation-dependent silencing of the Cyclin-dependent Kinase Inhibitor 2A (Cdkn2a) tumor suppressor, cooperates with insulator loss in OPCs. Coordinate inactivation of the Pdgfra insulator and Cdkn2a drives gliomagenesis in vivo. Our study demonstrates the capacity of recurrent epigenetic lesions to drive gliomagenesis.https://cassyni-user-files-prod.s3.amazonaws.com/qQr4Rr14Jq38yHFRax96v https://cassyni.com/slides/outline/PBh2nU933Pjf1P7cL2jZa5 https://cassyni.com/events/PBh2nU933Pjf1P7cL2jZa5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NUCHoYLXCWVnsCYRqkz7Mg https://cassyni.com/events/PBh2nU933Pjf1P7cL2jZa5?videoPreview=1 Organic Transistorsnohttps://cassyni.com/events/PBh2nU933Pjf1P7cL2jZa5?videoPreview=12023-02-22T00:00:00+00:005515.4Thieme GroupNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/NUCHoYLXCWVnsCYRqkz7Mg https://cassyni.com/events/8NEuPxjHsf82hSpuKNuq2M/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PviyWSMWwQzwdeN7iMmE1C https://cassyni.com/events/Ya1WfTS1P6Fvs8akFAD8Sh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Hfs4zsAnyrc9EZhtAbt7L2 https://cassyni.com/slides/outline/2w7FtScX3d2xJaafiTv32u https://cassyni.com/events/2w7FtScX3d2xJaafiTv32u/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9toxPBWc3SqkqRxP1QxFCa https://cassyni.com/events/2w7FtScX3d2xJaafiTv32u?videoPreview=1 Gain curves and sex allocation: why the Shaw-Mohler equation works and when it doesn'tnohttps://cassyni.com/events/2w7FtScX3d2xJaafiTv32u?videoPreview=12024-02-20T12:00:00+00:002343.08Royal Society PublishingFitness gain curves were introduced into the framework of the Shaw-Mohler equation, the foundation of sex allocation theory. I return to this equation to consider how it embodies the rare-sex advantage underlying frequency-dependent selection on the sex ratio. The Shaw-Mohler formulation is based on the numbers of males and females randomly mating in a panmictic population. Gain curves were meant to describe reproductive success through male and female functions in hermaphrodites and were inserted in place of male and female numbers in the Shaw-Mohler equation. In doing so, gain curves bypass the implicit mating process in the Shaw-Mohler argument that creates frequency-dependent selection. Gain curves can then lead to anomalies like unequal total male and female fitness in a population. If gain curves truly represent fitness gain, they must have a population-level effect on both sexes, a basic necessity of sexual reproduction. The blurring of inputs with fitness outcome has lead to misinterpretation of what gain curves mean in reproductive ecology. They lack causal efficacy with respect to sex allocation. Because gain curves have been a staple of evolutionary ecology for decades, the implication is that much of our understanding of sexual allocation in hermaphrodites needs to be revisited. I outline some directions such an effort might take.https://cassyni-user-files-prod.s3.amazonaws.com/9toxPBWc3SqkqRxP1QxFCa https://cassyni.com/events/3Rkrw8G3V5b1JM7ZJuCqJD/seminar/qa https://cassyni.com/slides/outline/3Rkrw8G3V5b1JM7ZJuCqJD https://cassyni.com/events/3Rkrw8G3V5b1JM7ZJuCqJD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EDUzYARStCgcU5HcTsHrTx https://cassyni.com/events/3Rkrw8G3V5b1JM7ZJuCqJD?videoPreview=1 Modularity of biological systems: a link between structure and functionnohttps://cassyni.com/events/3Rkrw8G3V5b1JM7ZJuCqJD?videoPreview=12024-04-03T15:00:00+00:002971.2Royal Society PublishingThis paper addresses two topics in systems biology, the hypothesis that biological systems are modular and the problem of relating structure and function of biological systems. The focus here is on gene regulatory networks, represented by Boolean network models, a commonly used tool. Most of the research on gene regulatory network modularity has focused on network structure, typically represented through either directed or undirected graphs. But since gene regulation is a highly dynamic process as it determines the function of cells over time, it is natural to consider functional modularity as well. One of the main results is that the structural decomposition of a network into modules induces an analogous decomposition of the dynamic structure, exhibiting a strong relationship between network structure and function. An extensive simulation study provides evidence for the hypothesis that modularity might have evolved to increase phenotypic complexity while maintaining maximal dynamic robustness to external perturbations.https://cassyni-user-files-prod.s3.amazonaws.com/EDUzYARStCgcU5HcTsHrTx https://cassyni.com/slides/outline/DoNYuUr4hhDRprQhL19iyj https://cassyni.com/events/DoNYuUr4hhDRprQhL19iyj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/YFrQVhaFhErABhyyXtoVxS https://cassyni.com/events/DoNYuUr4hhDRprQhL19iyj?videoPreview=1 Probabilistic Numerics — Computation as Machine Learningnohttps://cassyni.com/events/DoNYuUr4hhDRprQhL19iyj?videoPreview=12021-12-01T11:00:00+00:003511.24Data-Centric Engineering JournalNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/YFrQVhaFhErABhyyXtoVxS https://cassyni.com/events/PgpDmrYdKz37ABfhjPGGd3/seminar/qa https://cassyni.com/slides/outline/PgpDmrYdKz37ABfhjPGGd3 https://cassyni.com/events/PgpDmrYdKz37ABfhjPGGd3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6qov4yspyVePWy8t1uxpDt https://cassyni.com/events/PgpDmrYdKz37ABfhjPGGd3?videoPreview=1 Improving depth uncertainty in plenoptic camera-based velocimetrynohttps://cassyni.com/events/PgpDmrYdKz37ABfhjPGGd3?videoPreview=12024-06-18T14:00:00+00:002934.36Experiments in FluidsThis work describes the development of a particle tracking velocimetry (PTV) algorithm designed to improve three-dimensional (3D), three-component velocity field measurements using a single plenoptic camera. Particular focus is on mitigating the longstanding depth uncertainty issues that have traditionally plagued plenoptic particle image velocimetry (PIV) experiments by leveraging the camera’s ability to generate multiple perspective views of a scene in order to assist both particle triangulation and tracking. 3D positions are first estimated via light field ray bundling (LFRB) whereby particle rays are projected into the measurement volume using image-to-object space mapping. Tracking is subsequently performed independently within each perspective view, providing a statistical amalgamation of each particle’s predicted motion through time in order to help guide 3D trajectory estimation while simultaneously protecting the tracking algorithm from physically unreasonable fluctuations in particle depth positions. A synthetic performance assessment revealed a reduction in the average depth errors obtained by LFRB as compared to the conventional multiplicative algebraic reconstruction technique when estimating particle locations. Further analysis using a synthetic vortex ring at a magnification of − 0.6 demonstrated plenoptic-PIV capable of maintaining the equivalent of 0.1–0.15 voxel accuracy in the depth domain at a spacing to displacement ratio of 5.3–10.5, an improvement of 84–89% compared to plenoptic-PIV. Experiments were conducted at a spacing to displacement ratio of approximately 5.8 to capture the 3D flow field around a rotor within the rotating reference frame. The resulting plenoptic-PIV/PTV vector fields were evaluated with reference to a fixed frame stereoscopic-PIV (stereo-PIV) validation experiment. A systematic depth-wise (radial) component of velocity directed toward the wingtip, consistent with observations from prior literature and stereo-PIV experiments, was captured by plenoptic-PTV at magnitudes similar to the validation data. In contrast, the plenoptic-PIV did not discern any coherent indication of radial motion. Our algorithm constitutes a significant advancement in enhancing the functionality and versatility of single-plenoptic camera flow diagnostics by directly addressing the primary limitation associated with plenoptic imaging.https://cassyni-user-files-prod.s3.amazonaws.com/6qov4yspyVePWy8t1uxpDt https://cassyni.com/events/LEGzT51xFnAU8VN95itK6D/seminar/qa https://cassyni.com/slides/outline/LEGzT51xFnAU8VN95itK6D https://cassyni.com/events/LEGzT51xFnAU8VN95itK6D/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DdRxj4Vhs9WxG3WxgmRjok https://cassyni.com/events/LEGzT51xFnAU8VN95itK6D?videoPreview=1 Women's Healthcare: A Full Spectrum Viewnohttps://cassyni.com/events/LEGzT51xFnAU8VN95itK6D?videoPreview=12025-01-24T15:00:00+00:003717.76Women's HealthEven when focusing on women and gender-expansive populations, many groups remain underrepresented in medical and scientific research. As a result, examining trends in women’s healthcare often unearths the vastly different experiences of individuals with minoritized identities. Highlighting issues facing vulnerable groups is a necessary first step toward addressing the systemic issues women and gender-expansive people from all walks of life face when seeking and receiving healthcare. This special collection aims to advance scholarship at the intersection of women’s health and diversity, equity, and inclusion (DEI). We aim to illuminate how diverse experiences and systemic inequities shape health outcomes, access to care, and overall well-being for women and gender-expansive groups across various populations. Our goal is to contribute to a more comprehensive understanding of the full spectrum of issues which influence women's health and to foster dialogue that supports more equitable and inclusive healthcare practices.https://cassyni-user-files-prod.s3.amazonaws.com/DdRxj4Vhs9WxG3WxgmRjok https://cassyni.com/events/WbtgRRbyUPntezfH6pqCmj/seminar/qa https://cassyni.com/slides/outline/WbtgRRbyUPntezfH6pqCmj https://cassyni.com/events/WbtgRRbyUPntezfH6pqCmj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/ErXc1NSPUYVdjnduuVR9RG https://cassyni.com/events/WbtgRRbyUPntezfH6pqCmj?videoPreview=1 The Risks and Rewards of African Entrepreneurship: Overcoming Africa’s Challenging Landscapenohttps://cassyni.com/events/WbtgRRbyUPntezfH6pqCmj?videoPreview=12024-06-13T16:00:00+00:003332.04Lived Places PublishingA conversation between **Drew Harris**, The Emergent Entrepreneur Collection Editor at Lived Places Publishing and **Ike Onyema Obi**, author of [*A West African Entrepreneur's Challenging Path to Financial Freedom: For Future and Family*](https://livedplacespublishing.com/book/isbn/9781916704701?utm_source=MB&utm_medium=cassyni&utm_campaign=emergent-entrepreneur&utm_content=Obi). Ike is a Nigerian entrepreneur whose path to business success reflects the challenges many emergent entrepreneurs face. Ike has mastered being agile and resilient in an African context - taking risks and seizing opportunities, filling knowledge voids by learning persistently, and shaping his networks to help grow his businesses.https://cassyni-user-files-prod.s3.amazonaws.com/ErXc1NSPUYVdjnduuVR9RG https://cassyni.com/events/X6YHU7FVurLwemCAhG8133/seminar/qa https://cassyni.com/slides/outline/X6YHU7FVurLwemCAhG8133 https://cassyni.com/events/X6YHU7FVurLwemCAhG8133/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9FCJSNA9JoPjRWsx2pkqHx https://cassyni.com/events/X6YHU7FVurLwemCAhG8133?videoPreview=1 Learning PDEsnohttps://cassyni.com/events/X6YHU7FVurLwemCAhG8133?videoPreview=12024-11-18T14:00:00+00:003651.32Sci-Fi-TurboPDEs are considered to be language of physics as they provide mathematical descriptions of a whole range of physical phenomena. The complexity and prohibitive computational cost of traditional physics-based numerical schemes necessitates the search for fast and efficient surrogates, based on machine learning. In this lecture, we survey recent developments in the field of learning solution operators for PDEs by focussing on structure preserving neural operators and on foundation models for sample efficient and generalizable multi-operator learning. We also briefly discuss graph neural network based learning of PDEs on arbitrary domain geometries and conditional Diffusion models for learning multi-scale physical systems such as Turbulent Fluid Flows. https://cassyni-user-files-prod.s3.amazonaws.com/9FCJSNA9JoPjRWsx2pkqHx https://cassyni.com/slides/outline/RfQdxb8j5pFsFtww6M8D3b https://cassyni.com/events/RfQdxb8j5pFsFtww6M8D3b/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Svub7cZVVXq7c3dMkG9Utv https://cassyni.com/events/RfQdxb8j5pFsFtww6M8D3b?videoPreview=1 AI/ML+Physics Part 2: Curating Training Datanohttps://cassyni.com/events/RfQdxb8j5pFsFtww6M8D3b?videoPreview=12024-03-01T12:00:00+00:002170.24Brunton LabThis video discusses the second stage of the machine learning process: (2) collecting and curating training data to inform the model. There are opportunities to incorporate physics into this stage of the process, such as data augmentation to incorporate known symmetries. SLB acknowledges support from the National Science Foundation AI Institute in Dynamic Systems and from The Boeing Company.https://cassyni-user-files-prod.s3.amazonaws.com/Svub7cZVVXq7c3dMkG9Utv https://cassyni.com/events/Te2h6S1aP7y6DC6AZpudF/seminar/qa https://cassyni.com/slides/outline/Te2h6S1aP7y6DC6AZpudF https://cassyni.com/events/Te2h6S1aP7y6DC6AZpudF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/L7Q4gcvj5pQ45ZpCLXYrNa https://cassyni.com/events/Te2h6S1aP7y6DC6AZpudF?videoPreview=1 Redesign and heterogeneous computingnohttps://cassyni.com/events/Te2h6S1aP7y6DC6AZpudF?videoPreview=12024-06-12T08:00:00+00:005452.08Nektar++ Development TeamThis session focuses on the redesign of Nektar++ operators to enable the heterogeneous (CPU/GPU) computing and its comprises the following talks 1. Multi-level pipelining for improved GPU performance 2. Redesigning the Nektar++ Operators for CPU/GPU Execution, a WIP 3. Performance Timinghttps://cassyni-user-files-prod.s3.amazonaws.com/L7Q4gcvj5pQ45ZpCLXYrNa https://cassyni.com/slides/outline/3vt3vWfdmftTT9feiFjYMB https://cassyni.com/events/3vt3vWfdmftTT9feiFjYMB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4eWjDDyuxhSFsoX5TvqFev https://cassyni.com/events/3vt3vWfdmftTT9feiFjYMB?videoPreview=1 Data-driven Modeling of Traveling Wavesnohttps://cassyni.com/events/3vt3vWfdmftTT9feiFjYMB?videoPreview=12020-11-06T14:00:00+00:00822.44Brunton LabIn this video, Ariana Mendible describes a dimensionality reduction method for dynamical systems with traveling waves, giving low-rank representations of wave shapes and interpretable models for the wave speeds.https://cassyni-user-files-prod.s3.amazonaws.com/4eWjDDyuxhSFsoX5TvqFev https://cassyni.com/events/GH6A5bqkk7jKLpuTgcJGVK/seminar/qa https://cassyni.com/slides/outline/GH6A5bqkk7jKLpuTgcJGVK https://cassyni.com/events/GH6A5bqkk7jKLpuTgcJGVK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3yrWXKjuhMZakpWT7cdmSv https://cassyni.com/events/GH6A5bqkk7jKLpuTgcJGVK?videoPreview=1 Publishing for Sustainable Development: Impact Beyond Academianohttps://cassyni.com/events/GH6A5bqkk7jKLpuTgcJGVK?videoPreview=12024-06-20T08:00:00+00:002011.68Topics at the heart of our communityThe Springer Nature SDG Programme was established to help turn research into real-world policies and solutions which aid the Sustainable Development Goals. Join Nicola Jones - Director of the Springer Nature SDG Programme - as she reveals how SDG-related articles can create impact beyond academic citations, presenting data from Springer Nature’s wider journal programme. This event will feature the example of BMC Public Health, which undertook a pilot project to publish auto-generated societal impact summaries to accompany original research articles. Lorena Verduci, Associate Editor for the journal, will also share insights from this initiative.https://cassyni-user-files-prod.s3.amazonaws.com/3yrWXKjuhMZakpWT7cdmSv https://cassyni.com/slides/outline/AqxWa5iyv5eEwxfE5hJUVs https://cassyni.com/events/AqxWa5iyv5eEwxfE5hJUVs/abstract https://cassyni-user-files-prod.s3.amazonaws.com/SThq8ZAVj1oHLGc381hjTt https://cassyni.com/events/AqxWa5iyv5eEwxfE5hJUVs?videoPreview=1 Neural Operator for Parametric PDEsnohttps://cassyni.com/events/AqxWa5iyv5eEwxfE5hJUVs?videoPreview=12021-03-05T14:00:00+00:003595.2AI Institute in Dynamic SystemsPartial Differential Equations (PDE) lay the foundation for modeling a wide variety of scientific phenomena. Traditional solvers tend to be slow when high-fidelity solutions are needed. We introduce neural-operator, a data-driven approach that aims to directly learn the solution operator of PDEs. Unlike neural networks that learn function mapping between finite-dimensional spaces, neural operator extends that to learning operator between infinite-dimensional spaces. This makes the neural operator independent of resolution and grid of training data and allows for zero-shot generalization to higher resolution evaluations. We find that the neural operator is able to solve the Navier-Stokes equation in the turbulent regime with a 1000x speedup compared to traditional methods.https://cassyni-user-files-prod.s3.amazonaws.com/SThq8ZAVj1oHLGc381hjTt https://cassyni.com/slides/outline/BLc7cmNWMYCHwjC7g8bGmB https://cassyni.com/events/BLc7cmNWMYCHwjC7g8bGmB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/767PPYLhWfoUXQwpDXmfrn https://cassyni.com/events/BLc7cmNWMYCHwjC7g8bGmB?videoPreview=1 Boreal plant roots do not grow deeper to take advantage of depressed water tablesnohttps://cassyni.com/events/BLc7cmNWMYCHwjC7g8bGmB?videoPreview=12024-06-06T18:40:00+00:00933.08New Phytologist Foundation Boreal bogs host large stores of terrestrial carbon as peat. Long-term stability of peat is threatened by global change via altered rhizosphere conditions, temperatures, and hydrology. High water tables, cold temperatures and low pH in bogs favors Sphagnum moss production over vascular plant functional types (PFTs): trees, shrubs and sedges. We hypothesize that warming will increase the growth of vascular plant roots, particularly in deeper peat as water tables sink. Additionally, we hypothesize elevated [CO2] to amplify root productivity responses to warming, by inducing greater plant nutrient demand via CO2 fertilization. We tested these hypotheses in the SPRUCE experiment, a whole-ecosystem warming gradient (+0 to +9 °C in 2.5°C steps) ✕ ambient and elevated (500 ppm) [CO2] manipulation. Manual minirhizotron images from 2015-2021 were used to estimate root production and depth for each PFT. Root production by ericaceous shrubs increased with warming under elevated, but not ambient [CO2]. Rather than being more deeply distributed under warming & elevated [CO2], this root production was either more shallowly distributed or remained at the same depth. Altogether these results suggest that vascular plants in boreal bogs will respond to global change through shallow root production, possibly to capture nutrients from recent litter inputs.https://cassyni-user-files-prod.s3.amazonaws.com/767PPYLhWfoUXQwpDXmfrn https://cassyni.com/slides/outline/MiFRhkUQyWkSciBeyoUc5K https://cassyni.com/events/MiFRhkUQyWkSciBeyoUc5K/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XfNCSYn4MCLkoYEenwaRyg https://cassyni.com/events/MiFRhkUQyWkSciBeyoUc5K?videoPreview=1 Plasticity of nutrient mechanism acquisition in the Amazonian understory under elevated atmospheric carbon dioxidenohttps://cassyni.com/events/MiFRhkUQyWkSciBeyoUc5K?videoPreview=12024-06-07T14:30:00+00:001054.6New Phytologist Foundation Approximately 60% of the Amazon rainforest grows on highly weathered soils with low levels of rock-derived nutrients. In such nutrient-limited ecosystems, plant communities' functional capacity and adaptability to facilitate efficient nutrient acquisition is decisive for a potential CO2 fertilization effect. To address this uncertainty, we designed an in situ open-top chamber (OTC) experiment, elevating CO2 (eCO2) by 250 ppm in the understory of a highly phosphorus-limited mature Amazonian tropical forest in Manaus, Brazil. Our results showed that under eCO2, plants intensified root foraging in the litter layer, adopting a “do-it-yourself” strategy, increasing both root length and area by 328% and 217%, respectively. In contrast, roots in the soil followed an “outsourcing” strategy by doubling arbuscular mycorrhizal colonization. Furthermore, eCO2 enhanced direct biochemical phosphorus (P) mineralization in the litter layer by increasing P release by 11% without changing litter decomposition. This suggests that under the eCO2 understory, plants maximize nutrient acquisition and maintain stand-level biomass growth by tackling different P sources within the litter-soil continuum, switching from mineral soil to litter-derived organic P sources. This mechanism directly influences Amazonian rainforest C and nutrient cycling and its resilience to climate change.https://cassyni-user-files-prod.s3.amazonaws.com/XfNCSYn4MCLkoYEenwaRyg https://cassyni.com/events/JFiCNxwjuJsob1t6L96eYV/seminar/qa https://cassyni.com/slides/outline/JFiCNxwjuJsob1t6L96eYV https://cassyni.com/events/JFiCNxwjuJsob1t6L96eYV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XCJxZJ5xwpftxEB3E1TAfG https://cassyni.com/events/JFiCNxwjuJsob1t6L96eYV?videoPreview=1 Introduction to the 12th international Biometals webinars, Zinc and copper interact with tubulin and actin to form neuronal dendrites and synapses, Dmt1 and ferroportin transport iron and manganese in SLC30A10 deficiencynohttps://cassyni.com/events/JFiCNxwjuJsob1t6L96eYV?videoPreview=12025-02-04T14:00:00+00:004819.0BioMetalsZinc and copper play roles in neuronal synaptic functions, particularly in synaptogenesis and synaptic plasticity, but the molecular mechanisms are not fully understood. Due to low metal concentrations and sub-micron size of synaptic compartments, studying these roles is challenging. To address this, we developed a correlative nano-imaging approach that combines protein and metal detection. We used STED (stimulated emission depletion) super resolution microscopy to locate fluorescently labeled proteins and SXRF (synchrotron radiation X-ray fluorescence) for high-resolution imaging of metals in the same regions, to study the distribution of zinc and copper in synaptic compartments of primary rat hippocampal neurons. We found that zinc interacts with tubulin in dendrites and axons, is present in the postsynaptic density, and copper co-localizes with F-actin in synaptic compartments. Quantitative immunofluorescence data confirmed these interactions, showing that zinc affects tubulin expression and copper affects F-actin structures. Our results suggest that zinc is essential for the formation of the cytoskeletal structure in neurons, while copper plays a role in synaptic plasticity, key for memory processing. SLC30A10 deficiency is a disease of severe manganese excess attributed to loss of SLC30A10-dependent manganese excretion via the gastrointestinal tract. Patients develop dystonia, cirrhosis, and polycythemia. They are treated with chelators but also respond to oral iron, suggesting that iron can outcompete manganese for absorption in this disease. While SLC11A2 (DMT1) and SLC40A1 (ferroportin) are essential for dietary iron absorption, their role in manganese homeostasis is debated. In this study, we explore potential overlaps in manganese and iron absorption in Slc30a10-deficient mice. We first establish that manganese absorption is paradoxically increased in Slc30a10-deficient mice despite manganese excess. We next show that intestinal deficiency in Dmt1 or ferroportin not only attenuates aberrant manganese absorption but also prominently decreases manganese levels in Slc30a10-deficient mice. Finally, we demonstrate that intestinal Slc30a10 deficiency is a key driver of aberrant Mn absorption, as it impairs manganese export from enterocytes back into the gastrointestinal tract. Our work demonstrates that aberrant absorption contributes prominently to SLC30A10 deficiency, a disease previously attributed solely to impaired excretion, and expands our understanding of biological interactions between iron and manganese. Based on these results, we propose a reconsideration of the role of iron transporters in manganese homeostasis is warranted.https://cassyni-user-files-prod.s3.amazonaws.com/XCJxZJ5xwpftxEB3E1TAfG https://cassyni.com/slides/outline/LixDcPBN6beHwxMesq1HGR https://cassyni.com/events/LixDcPBN6beHwxMesq1HGR/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GAQtPjEXkxmJ2iEbe2Je3Y https://cassyni.com/events/LixDcPBN6beHwxMesq1HGR?videoPreview=1 The Digital Twin Earth Hydrology Platformnohttps://cassyni.com/events/LixDcPBN6beHwxMesq1HGR?videoPreview=12024-05-29T16:00:00+00:005329.72Frontiers in ScienceClimate change is profoundly affecting the global water cycle, increasing the likelihood and severity of extreme water-related events. Better decision-support systems are vital to accurately predict and monitor water-related environmental disasters and optimally manage water resources. These must integrate advances in remote sensing, in situ, and citizen observations with high-resolution Earth system modeling, artificial intelligence (AI), information and communication technologies, and high-performance computing. Digital Twin Earth (DTE) models are a ground-breaking solution offering digital replicas to monitor and simulate Earth processes with unprecedented spatiotemporal resolution. Advances in Earth observation (EO) satellite technology are pivotal, and here we provide a roadmap for the exploitation of these methods in a DTE for hydrology. The 4-dimensional DTE Hydrology datacube now fuses high-resolution EO data and advanced modeling of soil moisture, precipitation, evaporation, and river discharge, and here we report the latest validation data in the Mediterranean Basin. This system can now be explored to forecast flooding and landslides and to manage irrigation for precision agriculture. Large-scale implementation of such methods will require further advances to assess high-resolution products across different regions and climates; create and integrate compatible multidimensional datacubes, EO data retrieval algorithms, and models that are suitable across multiple scales; manage uncertainty both in EO data and models; enhance computational capacity via an interoperable, cloud-based processing environment embodying open data principles; and harness AI/machine learning. We outline how various planned satellite missions will further facilitate a DTE for hydrology toward global benefit if the scientific and technological challenges we identify are addressed.https://cassyni-user-files-prod.s3.amazonaws.com/GAQtPjEXkxmJ2iEbe2Je3Y https://cassyni.com/events/XbDWdRQukfpmUEBgVNEyDF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Jqz7c6jwASnfPfSA2sN1uG https://cassyni.com/events/EJXN1VmYPeSeoMRQw2Wbwb/seminar/qa https://cassyni.com/slides/outline/EJXN1VmYPeSeoMRQw2Wbwb https://cassyni.com/events/EJXN1VmYPeSeoMRQw2Wbwb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2Em6AayyErFsWMnMnmWFWn https://cassyni.com/events/EJXN1VmYPeSeoMRQw2Wbwb?videoPreview=1 No phylogenetic evidence for angiosperm mass extinction at the Cretaceous–Palaeogene (K-Pg) boundarynohttps://cassyni.com/events/EJXN1VmYPeSeoMRQw2Wbwb?videoPreview=12024-09-16T10:00:00+00:003548.24Royal Society PublishingThe Cretaceous–Palaeogene mass extinction event (K-Pg) witnessed upwards of 75% of animal species going extinct, most notably among these are the non-avian dinosaurs. A major question in macroevolution is whether this extinction event influenced the rise of flowering plants (angiosperms). The fossil record suggests that the K-Pg event had a strong regional impact on angiosperms with up to 75% species extinctions, but only had a minor impact on the extinction rates of major lineages (families and orders). Phylogenetic evidence for angiosperm extinction dynamics through time remains unexplored. By analysing two angiosperm mega-phylogenies containing approximately 32 000–73 000 extant species, here we show relatively constant extinction rates throughout geological time and no evidence for a mass extinction at the K-Pg boundary. Despite high species-level extinction observed in the fossil record, our results support the macroevolutionary resilience of angiosperms to the K-Pg mass extinction event via survival of higher lineages. Image credit: [Rhus nigricans (fossil leaf) (Green River Formation, Eocene; Utah, USA). James St. John, Wikimedia Commons.](https://commons.wikimedia.org/wiki/File:Rhus_nigricans_(fossil_leaf)_(Green_River_Formation,_Eocene;_Utah,_USA)_2_(44366947535).jpg)https://cassyni-user-files-prod.s3.amazonaws.com/2Em6AayyErFsWMnMnmWFWn https://cassyni.com/slides/outline/7PSuMviCFEgsJYRqZawfnu https://cassyni.com/events/7PSuMviCFEgsJYRqZawfnu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2VHnjmgJCQAL8M2FgBJ4CE https://cassyni.com/events/7PSuMviCFEgsJYRqZawfnu?videoPreview=1 PCAN Podcast Episode 4: Dr. Ditonno on new imaging techniques for PCa diagnosisnohttps://cassyni.com/events/7PSuMviCFEgsJYRqZawfnu?videoPreview=12024-03-10T14:00:00+00:001854.64Research Seminars by Springer NatureNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/2VHnjmgJCQAL8M2FgBJ4CE https://cassyni.com/slides/outline/xKFrQbRRCbnugBbxfwsoT https://cassyni.com/events/xKFrQbRRCbnugBbxfwsoT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NWQzcRRgMQqVaVpWw66nfQ https://cassyni.com/events/xKFrQbRRCbnugBbxfwsoT?videoPreview=1 Ice Giant Magnetospheresnohttps://cassyni.com/events/xKFrQbRRCbnugBbxfwsoT?videoPreview=12024-07-10T14:00:00+00:001453.12MOP2024The Ice Giant Magnetospheres provide some of the most interesting natural laboratories for studying the influence of large obliquities, rapid rotation, highly asymmetric magnetic fields, and large Alfvénic and sonic Mach numbers on magnetospheric processes. Uranus is subjected to extreme seasonal variations resulting from the nearly 98° tilt of its rotation axis. At both Uranus and Neptune, the solar wind-magnetosphere interaction varies dramatically on diurnal and seasonal timescales due to the apparent offset and large tilt of the dipole field. With in situ observations limited to a single encounter by the Voyager 2 spacecraft, a growing number of analytical and numerical models have been put forward to characterize ice giant magnetospheres and test hypothesis related to magnetospheric boundary layers, the solar wind interaction, the formation of the radiation belts, understanding charged particle precipitation, aurora, and energy deposition to the atmosphere, and quantifying potential plasma sources and the distribution of plasma observed. Yet despite these recent studies, many questions regarding the observations of the Ice Giant magnetospheres remain unanswered. This has led to great community interest in revisiting these distant worlds, with the Decadal Survey placing the Uranus Orbiter and Probe (UOP) as the highest flagship mission priority, and the Planetary Mission Concept Study Neptune Odyssey receiving tremendous support as well. In this tutorial I will describe the current understanding of the ice giant magnetosphere, as well as the key magnetospheric science questions motivating the UOP mission.https://cassyni-user-files-prod.s3.amazonaws.com/NWQzcRRgMQqVaVpWw66nfQ https://cassyni.com/slides/outline/GmmPEv1AawD9AHtyUiREfX https://cassyni.com/events/GmmPEv1AawD9AHtyUiREfX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FgLyKaSZNARFR4HZ4oSQHU https://cassyni.com/events/GmmPEv1AawD9AHtyUiREfX?videoPreview=1 Adjoining an order unit to a normed linear spacenohttps://cassyni.com/events/GmmPEv1AawD9AHtyUiREfX?videoPreview=12021-05-27T14:00:00+00:003626.32Positivity Journal, SpringerNatureUsing a technique of adjoining an order unit to a normed linear space, we have characterized strictly convex spaces among normed linear spaces and Hilbert spaces among strictly convex Banach spaces respectively. This leads to a generalization of spin factors and provides a new class of absolute order unit spaces which is denoted as tracial absolute order unit spaces. In addition, we have obtained their functional representation and studied unital absolute value preserving maps on these spaces.https://cassyni-user-files-prod.s3.amazonaws.com/FgLyKaSZNARFR4HZ4oSQHU https://cassyni.com/events/BqHLn5XvCMg7mCBdUEiEwP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7aK1sWJSDQYS6bVpdnq4H4 https://cassyni.com/events/JkPRYH79k8MdQUsc8FDcih/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Vbg7boVEQ6mCiybMmVYSv2 https://cassyni.com/slides/outline/KF32axkgBaugQFQVigWQz1 https://cassyni.com/events/KF32axkgBaugQFQVigWQz1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TQYSCCjgYQGBtKQmPw7k5U https://cassyni.com/events/KF32axkgBaugQFQVigWQz1?videoPreview=1 AI and mathematical modelling in dialysis at Renal Research Institutenohttps://cassyni.com/events/KF32axkgBaugQFQVigWQz1?videoPreview=12024-08-21T08:00:00+00:004756.04NoneNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/TQYSCCjgYQGBtKQmPw7k5U https://cassyni.com/events/SA7VEXp2KzfTu4Q5685M8h/abstract https://cassyni-user-files-prod.s3.amazonaws.com/ViN9RF9PdT1ecV3vcVoKJn https://cassyni.com/slides/outline/QgCJD7PLQyvXcp7MXGLNtM https://cassyni.com/events/QgCJD7PLQyvXcp7MXGLNtM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HW8GbxsuBmKeHrCt9hX2cW https://cassyni.com/events/QgCJD7PLQyvXcp7MXGLNtM?videoPreview=1 The Microbiome side of OBGYNnohttps://cassyni.com/events/QgCJD7PLQyvXcp7MXGLNtM?videoPreview=12024-06-11T11:00:00+00:001158.0Microbiome Virtual International Forum We will do a recap of our microbiome work in Obstetrics and Gynecology, starting with our findings in healthy populations and natural variation. Then transitioning to healthy obstetrics and preterm labor. And wrapping up with gynecologic cancers, particularly endometrial and ovarian cancer.https://cassyni-user-files-prod.s3.amazonaws.com/HW8GbxsuBmKeHrCt9hX2cW https://cassyni.com/slides/outline/UdMWTx3eXHRxFzsddoyyrd https://cassyni.com/events/UdMWTx3eXHRxFzsddoyyrd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/MTUqfD9R7bJnZ57xPAWtbg https://cassyni.com/events/UdMWTx3eXHRxFzsddoyyrd?videoPreview=1 Klebsiella oxytoca mediates colonization resistance against multi-drug resistant Klebsiella pneumoniae in the gut via cooperative carbohydrate competitionnohttps://cassyni.com/events/UdMWTx3eXHRxFzsddoyyrd?videoPreview=12021-09-14T12:00:00+00:00718.0Microbiome Virtual International ForumGut colonization with multi-drug resistant (MDR) bacteria enhances the risk of bloodstream infections in susceptible individuals. We demonstrate highly-variable degrees of ex vivo colonization resistance against a carbapenem-resistant Klebsiella pneumoniae strain in human feces samples and subsequently isolated from protected donors diverse K. oxytoca strains. Several of these K. oxytoca strains reduced gut colonization of MDR K. pneumoniae strains in antibiotic-treated and gnotobiotic mouse models. Comparative analysis of K. oxytoca strains identified competition for specific carbohydrates as a key factor for colonization resistance. In addition to direct competition between K. oxytoca and K. pneumoniae, cooperation with additional commensals was required to reestablish full colonization resistance and gut decolonization. Finally, K. oxytoca also protected humanized microbiota mice generated from susceptible donors against K. pneumoniae colonization demonstrating the potential of commensal K. oxytoca strains as next-generation probiotics.https://cassyni-user-files-prod.s3.amazonaws.com/MTUqfD9R7bJnZ57xPAWtbg https://cassyni.com/slides/outline/5Qt7HpdytmQCm4wnp1A1FB https://cassyni.com/events/5Qt7HpdytmQCm4wnp1A1FB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HdTQYut6iJ22bR5qSFMost https://cassyni.com/events/5Qt7HpdytmQCm4wnp1A1FB?videoPreview=1 Microdiversity of the Vaginal Microbiome in Preterm Birthnohttps://cassyni.com/events/5Qt7HpdytmQCm4wnp1A1FB?videoPreview=12021-11-09T14:00:00+00:0059.48Microbiome Virtual International Forum Preterm birth (PTB) is the leading cause of neonatal mortality and morbidity. The vaginal microbiome has been associated with PTB, yet the mechanisms underlying this association remain largely unexplained. Our understanding of these associations could be informed by detecting microbial genomic adaptation to host-related stresses. To this end, we analyzed metagenomic data from 705 vaginal samples collected longitudinally during pregnancy from 40 women who delivered preterm spontaneously and 135 term controls from the Multi-Omic Microbiome Study-Pregnancy Initiative (MOMS-PI). We assembled 1,078 metagenome-assembled genomes, representing 157 species-level taxa from at least 8 bacterial phyla. We find that the vaginal microbiome of pregnancies that ended in PTB exhibits unique genetic profiles. Compared to pregnancies ending at term, it is more genetically diverse and harbors more virulence genes. It also harbors higher richness and diversity of antimicrobial resistant genes, likely promoted by plasmids. Interestingly, we found that Gardnerella vaginalis, a central vaginal pathobiont, is driving this high genetic diversity, particularly its genes involved in ribosome pathways and metabolism. We present evidence that this species undergoes more frequent recombination and stronger purifying selection in pregnancies which ended preterm. We further showed that the PTB-associated population structure of G. vaginalis may be related to optimization of growth rates. Overall, our results reveal novel associations between the vaginal microbiome and PTB from a population genetics perspective, and suggest that evolutionary processes acting on the vaginal microbiome may play a vital role in adverse pregnancy outcomes.https://cassyni-user-files-prod.s3.amazonaws.com/HdTQYut6iJ22bR5qSFMost https://cassyni.com/slides/outline/7t88XEsc64Ah81RMMh4dy7 https://cassyni.com/events/7t88XEsc64Ah81RMMh4dy7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DZFHVRNT756Dwnxkh1hfpa https://cassyni.com/events/7t88XEsc64Ah81RMMh4dy7?videoPreview=1 A mouse model of occult intestinal colonization demonstrating antibiotic-induced outgrowth of carbapenem-resistant Enterobacteriaceaenohttps://cassyni.com/events/7t88XEsc64Ah81RMMh4dy7?videoPreview=12022-01-11T15:00:00+00:0060.72Microbiome Virtual International Forum Background: The human intestinal microbiome is a complex community that contributes to host health and disease. In addition to normal microbiota, pathogens like carbapenem-resistant Enterobacteriaceae may be asymptomatically present. When these bacteria are present at very low levels, they are often undetectable in hospital surveillance cultures, known as occult or subclinical colonization. Through the use of antibiotics, these subclinical pathogens can increase to sufficiently high levels to become detectable, in a process called outgrowth. However, little is known about the interaction between gut microbiota and Enterobacteriaceae during occult colonization and outgrowth. Results: We developed a clinically-relevant mouse model for studying occult colonization. Conventional wild-type mice without antibiotic pre-treatment were exposed to K. pneumoniae but rapidly tested negative for colonization. This occult colonization was found to perturb the microbiome as detected by both 16S rRNA amplicon and shotgun metagenomic sequencing. Outgrowth of occult K. pneumoniae was induced either by a four-antibiotic cocktail or by individual receipt of ampicillin, vancomycin or azithromycin, which all reduced overall microbial diversity. Notably, vancomycin was shown to trigger K. pneumoniae outgrowth in only a subset of exposed animals (outgrowth-susceptible). To identify factors that underlie outgrowth susceptibility, we analyzed microbiome-encoded gene functions and were able to classify outgrowth-susceptible microbiomes using pathways associated with mRNA stability. Lastly, an evolutionary approach illuminated the importance of xylose metabolism in K. pneumoniae colonization, supporting xylose abundance as a second susceptibility indicator. We showed that our model is generalizable to other pathogens, including carbapenem-resistant Escherichia coli and Enterobacter cloacae. Conclusions: Our modeling of occult colonization and outgrowth could help the development of strategies to mitigate the risk of subsequent infection and transmission in medical facilities and the wider community. This study suggests that microbiota mRNA and small-molecule metabolites may be used to predict outgrowth-susceptibility. Link to OA paper: https://www.biorxiv.org/content/10.1101/2021.02.24.432587v1https://cassyni-user-files-prod.s3.amazonaws.com/DZFHVRNT756Dwnxkh1hfpa https://cassyni.com/slides/outline/4RauCTLw1rJ46K7ni2ggSH https://cassyni.com/events/4RauCTLw1rJ46K7ni2ggSH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/65VAYVn6Tresr9JWy6w5RY https://cassyni.com/events/4RauCTLw1rJ46K7ni2ggSH?videoPreview=1 Anatomy promotes neutral coexistence of strains in the human skin microbiomenohttps://cassyni.com/events/4RauCTLw1rJ46K7ni2ggSH?videoPreview=12022-03-08T14:00:00+00:00624.0Microbiome Virtual International Forum What enables strains of the same species to coexist in a microbiome? Here, we investigate whether host anatomy can explain strain co-residence of Cutibacterium acnes, the most abundant species on human skin. We reconstruct on-person evolution and migration using whole-genome sequencing of C. acnes colonies acquired from healthy subjects, including from individual skin pores, and find considerable spatial structure at the level of pores. Although lineages (sets of colonies separated by less than 100 mutations) with in vitro fitness differences coexist within centimeter-scale regions, each pore is dominated by a single lineage. Moreover, colonies from a pore typically have identical genomes. An absence of adaptive signatures suggests a genotype-independent source of low within-pore diversity. We therefore propose that pore anatomy imposes random single-cell bottlenecks; the resulting population fragmentation reduces competition and promotes coexistence. Our findings suggest that therapeutic interventions involving pore-dwelling species might focus on removing resident populations over optimizing probiotic fitness.https://cassyni-user-files-prod.s3.amazonaws.com/65VAYVn6Tresr9JWy6w5RY https://cassyni.com/slides/outline/EoCbAovxETvUcpQvj8da7o https://cassyni.com/events/EoCbAovxETvUcpQvj8da7o/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RXwZkNJ3M4asMCGs1mmAb8 https://cassyni.com/events/EoCbAovxETvUcpQvj8da7o?videoPreview=1 Promises for patients with disturbed gut-brain axis signalling: Does the intake of a probiotic mixture improve mental health of healthy subjects?nohttps://cassyni.com/events/EoCbAovxETvUcpQvj8da7o?videoPreview=12022-09-13T11:00:00+00:00656.04Microbiome Virtual International Forum Gut microbiota modifications, such as by probiotics, have an effect on health and disease via the microbiota-gut-brain axis, amongst others. Several clinical studies have shown that probiotics might affect brain activity and behaviour in healthy subjects and subjects with disturbed gut-brain axis signalling. In this double-blinded, placebo-controlled crossover functional magnetic resonance imaging study, 22 healthy subjects (age 243 years, 6m/16f) underwent a probiotic intervention containing Bifidobacterium longum R0175, Lactobacillus helveticus R0052 and Lactiplantibacillus plantarum R1012 (in total at least 3×109 CFU/day) and a placebo intervention in randomised order for 4 weeks each, separated by a 4-week washout period. The probiotic intervention resulted in significantly altered brain response patterns (brain activity and functional connectivity) towards an acute emotional challenge and an acute mental arithmetic stress task, without effects on subjective stress ratings or cortisol response. Also, alterations in non-evoked resting state functional connectivity were observed upon probiotic intervention. Autonomic nervous system function was not significantly affected, neither at rest nor during stress, by the probiotic intervention compared to the placebo. Also, cognitive performance (assessed by Stroop) was not affected by the probiotic intervention. Apart from effects on brain function, also psychological symptoms, such as depression symptoms and sleep patterns, were slightly affected, even if none of the subjects experienced mental dysfunction at baseline. Other ratings, such as anxiety, perceived health, quality of life and perceived workload were not affected. Similarly, the probiotic intervention did not affect perceived stress nor the cortisol awakening response in non-evoked situations. In terms of signalling molecules, serotonin showed slightly higher baseline-corrected serum concentrations after probiotics compared to placebo, while brain-derived neurotrophic factor concentrations were not affected. Also, markers of intestinal damage or systemic inflammation were not affected. No substantial effects on the gut microbiota composition were observed. The probiotic intervention evoked distinct changes in brain function and subtle changes in psychological symptoms even in a healthy study population. These results give promising hints that patients with a disturbed gut-brain axis function could benefit from probiotic intake.https://cassyni-user-files-prod.s3.amazonaws.com/RXwZkNJ3M4asMCGs1mmAb8 https://cassyni.com/slides/outline/9riYhyThqtPTDihaievaPf https://cassyni.com/events/9riYhyThqtPTDihaievaPf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Pofx5yXhoxeCmCQQpgPDie https://cassyni.com/events/9riYhyThqtPTDihaievaPf?videoPreview=1 Investigation of antibiotic resistome in hospital wastewater during the COVID-19 pandemic: Is the Initial Phase of the Pandemic Contributing to Antimicrobial Resistance?nohttps://cassyni.com/events/9riYhyThqtPTDihaievaPf?videoPreview=12023-01-16T11:00:00+00:00652.04Microbiome Virtual International Forum Since the COVID-19 pandemic started, there has been much speculation about how COVID-19 and antimicrobial resistance may be interconnected. In this study, untreated wastewater was sampled from Hospital A designated to treat COVID-19 patients during the first wave of the COVID-19 pandemic alongside Hospital B that did not receive any COVID-19 patients. Metagenomics was used to determine the relative abundance and mobile potential of antibiotic resistant genes (ARGs), prior to determining the correlation of ARGs with time/incidence of COVID-19. Our findings showed that ARGs resistant to macrolides, sulfonamides, and tetracyclines were positively correlated with time in Hospital A but not in Hospital B. Likewise, minor extended spectrum betalactamases (ESBLs) and carbapenemases of classes B and D were positively correlated with time, suggesting the selection of rare and/or carbapenem-resistant genes in Hospital A. This study highlighted concerns related to the dissemination of antimicrobial resistance (AMR) during the COVID-19 pandemic that may arise from antibiotic use and untreated hospital wastewater. Link to OA paper: https://doi.org/10.1021/acs.est.2c01834https://cassyni-user-files-prod.s3.amazonaws.com/Pofx5yXhoxeCmCQQpgPDie https://cassyni.com/slides/outline/NCxGyh9iDhA3FsdnyaRkAR https://cassyni.com/events/NCxGyh9iDhA3FsdnyaRkAR/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FHD3ttU3DCqaBAUfBbLVQa https://cassyni.com/events/NCxGyh9iDhA3FsdnyaRkAR?videoPreview=1 Gut microbiota patterns associated with duration of diarrhea in children under five years of age in Ethiopianohttps://cassyni.com/events/NCxGyh9iDhA3FsdnyaRkAR?videoPreview=12024-03-20T10:00:00+00:0067.28Microbiome Virtual International Forum Introduction: Diarrhea claims about 500,000 lives annually among children under five years of age and about 90% of those deaths occur in Sub-Saharan Africa and South Asia. Childhood mortality due to acute diarrhea (AD; less than 7 days of duration) is decreasing, but prolonged (ProD; 7-13 days of duration) and persistent (PD; more than 14 days of duration) diarrhea combined (ProPD) are responsible for increased morbidity and mortality in low- and middle- income countries (LMICs). Objectives: This study aimed to characterize the gut microbiota (GM) composition of children with acute diarrhea (AD) and prolonged or persistent diarrhea (ProPD) by comparing GM composition between these two groups and with non-diarrheal controls in a case-control study. Methods: The study included fecal samples from 1321 children 0-59 months old. After preprocessing based on sequencing depth, we analyzed the GM of 1313 children comparing 554 AD cases, 95 ProPD cases, and 663 frequency matched, non-diarrheal controls. All children were enrolled from Jimma, Ethiopia. The GM composition was determined using 16S rRNA gene (V4 region) amplicon sequencing. The observed zero-radius Operational Taxonomic Units (zOTUs) and Shannon diversity index were assessed, and Bray-Curtis dissimilarity metrics were generated and differences between groups evaluated by PERMANOVA. DESeq2 was used to determine taxa being differentially abundant between diarrhea subcategories and non-diarrheal controls. Results: All diarrhea cases (AD and ProPD) combined and each group separately were associated with a decrease in bacterial diversity compared to non-diarrheal controls. Relative to non-diarrheal controls, the GM of children with AD or ProPD was enriched in Escherichia spp., Campylobacter spp., and Streptococcus spp. The GM of children with AD or ProPD was characterized by a decreased relative abundance of Prevotella copri, Faecalibacterium prausnitzii and Dialister succinatiphilus compared to non-diarrheal controls. Similarly, compared to AD cases, ProPD cases were characterized by a decreased relative abundance of important gut commensals such as F. prausnitzii, Akkermansia muciniphila, Eubacterium hadrum and Blautia spp. Conclusion: The GM of children with AD and ProPD was enriched in putative pathogens as well as facultative anaerobes, while obligate anaerobes were reduced. The GM of children with ProPD was characterized by a more pronounced reduction of obligate anaerobic gut commensals compared to AD, suggesting that prolonged duration of diarrhea is accompanied by a depletion of healthy gut commensals. This indicates a potential role for targeted dietary supplements to restore gut eubiosis and/ or the use of next generation probiotics to improve ProPD treatment.https://cassyni-user-files-prod.s3.amazonaws.com/FHD3ttU3DCqaBAUfBbLVQa https://cassyni.com/slides/outline/KjiFkGv62QPWDiQ1WndPAD https://cassyni.com/events/KjiFkGv62QPWDiQ1WndPAD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HWQVkG2mDNaumP8WQyRmze https://cassyni.com/events/KjiFkGv62QPWDiQ1WndPAD?videoPreview=1 Prebiotic intervention with HAMSAB in untreated essential hypertensive patients assessed in a phase II randomized trialnohttps://cassyni.com/events/KjiFkGv62QPWDiQ1WndPAD?videoPreview=12023-02-15T13:00:00+00:00620.04Microbiome Virtual International Forum Fibers remain undigested until they reach the colon, where some are fermented by gut microbiota, producing metabolites called short-chain fatty acids (SCFAs), such as acetate and butyrate1. SCFAs lower blood pressure in experimental models2,3,4,5, but their translational potential is unknown. Here we present the results of a phase II, randomized, placebo-controlled, double-blind cross-over trial (Australian New Zealand Clinical Trials Registry ACTRN12619000916145) using prebiotic acetylated and butyrylated high-amylose maize starch (HAMSAB) supplementation6. Twenty treatment-naive participants with hypertension were randomized to 40 g per day of HAMSAB or placebo, completing each arm for 3 weeks, with a 3-week washout period between them. The primary endpoint was a reduction in ambulatory systolic blood pressure. Secondary endpoints included changes to circulating cytokines, immune markers and gut microbiome modulation. Patients receiving the HAMSAB treatment showed a clinically relevant reduction in 24-hour systolic blood pressure independent of age, sex and body mass index without any adverse effects. HAMSAB increased levels of acetate and butyrate, shifted the microbial ecosystem and expanded the prevalence of SCFA producers. In summary, a prebiotic intervention with HAMSAB could represent a promising option to deliver SCFAs and lower blood pressure in patients with essential hypertension. Link to paper: https://www.nature.com/articles/s44161-022-00197-4https://cassyni-user-files-prod.s3.amazonaws.com/HWQVkG2mDNaumP8WQyRmze https://cassyni.com/slides/outline/Y5vMuN6CzrEN7PdpV9C7JM https://cassyni.com/events/Y5vMuN6CzrEN7PdpV9C7JM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DvQ1uNvTbqPd77axfwPVka https://cassyni.com/events/Y5vMuN6CzrEN7PdpV9C7JM?videoPreview=1 Fusobacterium nucleatum subspecies exhibit oral niche-specific biasesnohttps://cassyni.com/events/Y5vMuN6CzrEN7PdpV9C7JM?videoPreview=12023-06-21T13:00:00+00:00552.04Microbiome Virtual International Forum Fusobacterium nucleatum, a ubiquitous member of the human oral and gut microbiomes, is strongly associated with the development of multiple human diseases including periodontitis, oral/extraoral abscesses, and several types of cancer. F. nucleatum is currently divided into four subspecies: F. nucleatum subspecies nucleatum (Fn. nucleatum), animalis (Fn. animalis), polymorphum (Fn. polymorphum), and vincentii/fusiforme (Fn. vincentii). Although these subspecies have been historically considered as functionally interchangeable, recent clinical studies of colorectal tumor-associated F. nucleatum have suggested this perception may be inaccurate. Consequently, we aimed to determine whether F. nucleatum subspecies prevalence in the oral cavity correlates with oral health status. Patient-matched specimens of dental plaque and odontogenic abscess were analyzed with both culture-independent and culture-dependent approaches using 58 and 44 paired samples, respectively. Pangenome, phylogenetic and functional enrichment analysis of Fusobacterium species and F. nucleatum subspecies were conducted using the Anvi’o workflow. Both culture-independent and -dependent analyses similarly revealed a highly biased distribution of F. nucleatum subspecies in the oral cavity, with most patients harboring multiple subspecies. In dental plaque, Fn. polymorphum is the dominant organism, whereas Fn. animalis is particularly prevalent within abscesses. Surprisingly, the most heavily studied subspecies, Fn. nucleatum, was only a minor constituent within the entire specimen collection. In agreement with the clinical data, phylogenetic and comparative genomic analyses identified substantial distinctions among F. nucleatum subspecies. The heterogeneous distribution of F. nucleatum subspecies within oral plaque and abscess specimens reveals niche-specific preferences, with Fn. animalis likely exhibiting the greatest pathogenic potential. Both the clinical and genomic data strongly suggest that each F. nucleatum subspecies likely comprises unique Fusobacterium species.https://cassyni-user-files-prod.s3.amazonaws.com/DvQ1uNvTbqPd77axfwPVka https://cassyni.com/slides/outline/SeniPqySAp9HiXPatECKJu https://cassyni.com/events/SeniPqySAp9HiXPatECKJu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Y1hGcauxnTg9PX8dYiDzrr https://cassyni.com/events/SeniPqySAp9HiXPatECKJu?videoPreview=1 Enabling Improved Aircraft Performance Through Floating Folding Wing Tipsnohttps://cassyni.com/events/SeniPqySAp9HiXPatECKJu?videoPreview=12023-02-22T08:00:00+00:003158.04Department of Aeronautics and AstronauticsThere is much current effort devoted towards achieving net zero emissions from aircraft; however, it will be many years before aircraft are powered by the likes of Sustainable Aviation Fuel, Hydrogen or electrical means.  Consequently, any concept that enables reduced fuel burn – and hence generates less emissions – will be extremely beneficial in the short term, and also in the future.  This presentation will provide an overview of the work at the University of Bristol relating to the use of floating folding wingtips to facilitate higher aspect ratios (lower drag), meet airport gate restrictions, enable gust loads alleviation and improve roll performance.   The talk will refer to many tests that have been performed from blue sky concept demonstrators through to small scale flight tests. Image credit: [Dan Convey (Unsplash)](https://unsplash.com/photos/the-wing-of-an-airplane-as-the-sun-shines-through-the-clouds-JT3BIsrYAs0).https://cassyni-user-files-prod.s3.amazonaws.com/Y1hGcauxnTg9PX8dYiDzrr https://cassyni.com/slides/outline/8NX8YFt9uGPJ9vD5DDgv7P https://cassyni.com/events/8NX8YFt9uGPJ9vD5DDgv7P/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BkF7mAmKYpKUvoH2EVLdin https://cassyni.com/events/8NX8YFt9uGPJ9vD5DDgv7P?videoPreview=1 Comparison of a Ramping and Steady State Excitation on the Bifurcation Structure of a Multi-bubble Systemnohttps://cassyni.com/events/8NX8YFt9uGPJ9vD5DDgv7P?videoPreview=12025-06-24T11:00:00+00:00746.08NODYSThe combination of experiment and numerical investigation has unlocked new understanding of the mechanisms that mediate the reverse bifurcation first described by Lauterborn and Cramer in 1981.https://cassyni-user-files-prod.s3.amazonaws.com/BkF7mAmKYpKUvoH2EVLdin https://cassyni.com/slides/outline/YaHjokasQhXCKbxv8zzDXj https://cassyni.com/events/YaHjokasQhXCKbxv8zzDXj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/K9wZLnxJjKgrTJWZXDLRhx https://cassyni.com/events/YaHjokasQhXCKbxv8zzDXj?videoPreview=1 Estimating Unstable Limit Cycles from Small Perturbations: A Minimal-Data-Driven Approachnohttps://cassyni.com/events/YaHjokasQhXCKbxv8zzDXj?videoPreview=12025-06-24T10:00:00+00:00829.64NODYSUnstable solutions, though less prominent than stable ones, are essential in assessing the dynamical integrity of stable steady-states, as basin boundaries are often formed by unstable saddle-type solutions and their stable manifolds. This study introduces a data-driven method to estimate unstable limit cycles around stable equilibria using only small perturbation trajectories near the equilibrium. The approach requires no mathematical model, relying solely on a single phase-space trajectory, making it computationally efficient and practical for real-world applications.https://cassyni-user-files-prod.s3.amazonaws.com/K9wZLnxJjKgrTJWZXDLRhx https://cassyni.com/slides/outline/RAZg7VszpqDgZZn1aqNb5f https://cassyni.com/events/RAZg7VszpqDgZZn1aqNb5f/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Crhj7hyFY6Zhh2C2NwzpSr https://cassyni.com/events/RAZg7VszpqDgZZn1aqNb5f?videoPreview=1 Rub Related Nonlinear Dynamics in a Noisy Non-Smooth Jeffcott Rotor Modelnohttps://cassyni.com/events/RAZg7VszpqDgZZn1aqNb5f?videoPreview=12025-06-24T10:00:00+00:00669.68NODYSStrong and discontinuous nonlinearities arising from friction, contact stiffness, clearances and unbalance excitation and random excitation due to parametric uncertainty make the dynamic analysis of a rotor-stator system complex. This paper presents the dynamics of a nonlinear and non-smooth Jeffcott rotor system. The effects of unbalance force, bearing clearance, rotor-stator impact, tangential rubbing, randomness in rotor parameters due to manufacturing error and assembly deviation are considered in formulating the equations of motion. Both normal impact and tangential rubbing between rotor and stator are modeled respectively as of Hertzian type and dry friction. The parametric uncertainty is modeled by appropriate white noise random processes.https://cassyni-user-files-prod.s3.amazonaws.com/Crhj7hyFY6Zhh2C2NwzpSr https://cassyni.com/slides/outline/TdohLv7d27zAvWFa8XHDob https://cassyni.com/events/TdohLv7d27zAvWFa8XHDob/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GSQMhfQoifaTVQLozCTNB8 https://cassyni.com/events/TdohLv7d27zAvWFa8XHDob?videoPreview=1 Anisotropic Effects on the Nonlinear Dynamics of the Hard-Magnetic Soft Actuatorsnohttps://cassyni.com/events/TdohLv7d27zAvWFa8XHDob?videoPreview=12025-06-24T11:00:00+00:00719.48NODYSIn recent years, there has been considerable research interest in hard-magnetic soft active materials due to their benefits, such as untethered, rapid, and reversible actuation, coupled with substantial shape change. Typically, these materials are formed by incorporating hard-magnetic particles into a soft matrix. The actuation process relies on the magnetic particles induced by the applied magnetic field on the soft matrix. Consequently, the efficiency of actuation is significantly influenced by the anisotropy of the soft matrix. This article presents a theoretical framework for modelling the dynamic behaviour of hard-magnetic soft materials and delves into an examination of how the transverse anisotropy impacts the actuation efficiency in dynamic mode. The analysis uncovers the pivotal role of transverse anisotropy in determining actuation efficiency. A physics-based Polignone material model is utilized to consider the transverse anisotropy of the HMSM. The governing equation for dynamic motion is derived using Euler-Lagrange’s principle for nonconservative systems, enabling the characterization of nonlinear oscillations under constant and periodic magnetic fluxes. The dynamic stability, resonance properties, dynamic response, and periodicity are examined through frequency response spectra, time history graphs, phase-plane diagrams, and Poincaré maps. The investigation aims to understand the effect of the anisotropy on the nonlinear oscillations and capture the dynamic behaviour of the actuators.https://cassyni-user-files-prod.s3.amazonaws.com/GSQMhfQoifaTVQLozCTNB8 https://cassyni.com/slides/outline/GGvRPpkSKxAxTxj3yCfchb https://cassyni.com/events/GGvRPpkSKxAxTxj3yCfchb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Yb6Sv6SmGPtUi5ttomuZUa https://cassyni.com/events/GGvRPpkSKxAxTxj3yCfchb?videoPreview=1 Diffusive Shock Acceleration from Plasma to Astrophysical Scalesnohttps://cassyni.com/events/GGvRPpkSKxAxTxj3yCfchb?videoPreview=12025-01-23T16:00:00+00:003204.12Journal of Plasma PhysicsInterpreting observations of extreme astrophysical phenomena requires a detailed understanding of the microphysical processes responsible for charged particle acceleration. In the standard picture, supernova remnants and other astrophysical shocks accelerate these particles, known as cosmic rays, via diffusive shock acceleration (DSA), an efficient mechanism that produces power-law distributions in momentum. However, both the multi-wavelength emission from astrophysical shocks—in particular, supernova remnants—and the populations of CRs detected at Earth reveal discrepancies between this standard theory and observations. To address these discrepancies, I will introduce a fast, semi-analytic modeling framework that self-consistently incorporates findings from state-of-the-art kinetic simulations. I will show how we can use this model to bridge the gap between plasma and astrophysical scales, and will predict the multi-messenger emission from astrophysical objects including supernova remnants, novae, and black hole winds.https://cassyni-user-files-prod.s3.amazonaws.com/Yb6Sv6SmGPtUi5ttomuZUa https://cassyni.com/events/AqnmtJdfVv5t56UpNHfpi9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TecQTFyWspMTJzBYoJCZkS https://cassyni.com/slides/outline/BLSNvzHBwNdw4s1hxixcyT https://cassyni.com/events/BLSNvzHBwNdw4s1hxixcyT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NDUkwjrk3nG4Babknfxfo4 https://cassyni.com/events/BLSNvzHBwNdw4s1hxixcyT?videoPreview=1 Cosmic ray plasma physics and magnetic dynamos in galaxy formationnohttps://cassyni.com/events/BLSNvzHBwNdw4s1hxixcyT?videoPreview=12023-04-27T15:00:00+00:003131.28Journal of Plasma PhysicsUnderstanding the physics of galaxy formation is an outstanding problem in modern astrophysics. Recent cosmological simulations have demonstrated that feedback by star formation, supernovae and active galactic nuclei appears to be critical in obtaining realistic disk galaxies and to slow down star formation to the small observed rates. However the particular physical processes underlying these feedback processes still remain elusive. In particular, many of these simulations neglected magnetic fields and relativistic particle populations (so-called cosmic rays). Those are known to provide a pressure support comparable to the thermal gas in our Galaxy and couple dynamically and thermally to the gas, which seriously questions their neglect. Early attempts to include magnetic fields and cosmic rays put the plasma kinetics of wave-particle interactions into the limelight for explaining the power of galactic winds and for regulating star formation in and cosmic accretion onto galaxies. After introducing the underlying physical concepts, I will present our recent efforts to model kinetic plasma physics in macroscopic hydrodynamical models of galaxy formation. In particular, I will explain how cosmic rays interact with and propagate through the magnetized plasma in the interstellar and circumgalactic media. I will elucidate the role of plasma instabilities in regulating the momentum transfer from cosmic rays to the background plasma and how we can observationally test these theoretical considerations using new high-sensitivity MeerKAT observations. I will then demonstrate that cosmic rays play a decisive role in the formation and evolution of spiral galaxies by providing feedback that regulates star formation and drives gas out in galactic winds. Comparing cosmic ray spectra of electrons and protons to observational data and studying the correlation of the far-infrared emission with the gamma-ray and radio emission from galaxies enables us to test the cosmic ray feedback and dynamo models for the growth of galactic magnetic fields. This argues that a complete understanding of galaxy formation necessarily includes plasma astrophysics.https://cassyni-user-files-prod.s3.amazonaws.com/NDUkwjrk3nG4Babknfxfo4 https://cassyni.com/slides/outline/Mi5h1yP6ZMC5jr1FGPqxHb https://cassyni.com/events/Mi5h1yP6ZMC5jr1FGPqxHb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KuP3p2F8CC6cjugDVow6aa https://cassyni.com/events/Mi5h1yP6ZMC5jr1FGPqxHb?videoPreview=1 Advances in Stellarator Design in Nuclear Fusion Research: The Direct Optimisation Architecturenohttps://cassyni.com/events/Mi5h1yP6ZMC5jr1FGPqxHb?videoPreview=12023-04-06T15:00:00+00:003352.64Journal of Plasma PhysicsIn pursuit of magnetic confinement nuclear fusion, magnetic fields of premier quality are imperative. These fields must sustain high-heat plasmas for an adequate amount of time while also enabling control of plasma density, fast particle management, and turbulence regulation. The standard design of stellarator machines, as seen in experiments such as HSX and W7-X, optimises magnetic fields and coils separately, resulting in limited engineering tolerances and often neglect turbulent transport in the optimisation process. Furthermore, such process is highly dependent on the initial conditions used and often needs multiple restarts with relaxed requirements, making the process inefficient and potentially compromising the optimal balance between alpha particles, neoclassical transport, and turbulence. Recent breakthroughs in the optimisation of stellarator devices, such as direct near-axis designs, integrated plasma-coil optimisation algorithms, precise quasisymmetric and quasi-isodynamic fields, and direct turbulence optimisation, are revolutionising the way in which these machines are designed. The main outcomes of these advancements, as well as the prospects for a more efficient fusion device, will be discussed in this presentation.https://cassyni-user-files-prod.s3.amazonaws.com/KuP3p2F8CC6cjugDVow6aa https://cassyni.com/slides/outline/JFYThBrRV9KSi9hgcjTzkm https://cassyni.com/events/JFYThBrRV9KSi9hgcjTzkm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HGziUuPVfCj2nUtQnCFg4v https://cassyni.com/events/JFYThBrRV9KSi9hgcjTzkm?videoPreview=1 Generalized entropy production in nonthermal collisionless plasmasnohttps://cassyni.com/events/JFYThBrRV9KSi9hgcjTzkm?videoPreview=12022-04-21T15:00:00+00:003772.36Journal of Plasma PhysicsCollisionless plasmas develop nonthermal particle distributions after being energized, and thus enter a state of low Boltzmann-Gibbs entropy. While the Vlasov equation predicts that Boltzmann-Gibbs entropy is formally conserved (along with an infinite set of other Casimir invariants), anomalous entropy production may be enabled by phase mixing, nonlinear entropy cascades, etc. The characterization of entropy production for various irreversible processes is a fundamental problem at the frontier of plasma physics. In this talk, I will describe how entropy production (in a generalized sense) can be represented by the evolution of an infinite set of dimensional quantities derived from the Vlasov equation, the so-called "Casimir momenta", which characterize violations of the Vlasov equation (and therefore irreversibility) at different energy scales. I will then suggest that Casimir momenta may be used to construct models of nonthermal particle acceleration in plasma processes of sufficient complexity, such as turbulence or magnetic reconnection, providing a possible route to understanding the prevalence and properties of power-law distributions. These ideas may open a new perspective into particle energization in collisionless plasmas.https://cassyni-user-files-prod.s3.amazonaws.com/HGziUuPVfCj2nUtQnCFg4v https://cassyni.com/slides/outline/LinUvc63gS5w56BFARNdUh https://cassyni.com/events/LinUvc63gS5w56BFARNdUh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KkEjiKd7rVVX9RMyKtAJnr https://cassyni.com/events/LinUvc63gS5w56BFARNdUh?videoPreview=1 Plasma physics of Fast Radio Burstsnohttps://cassyni.com/events/LinUvc63gS5w56BFARNdUh?videoPreview=12022-09-08T15:00:00+00:002929.32Journal of Plasma PhysicsFast Radio Bursts are millisecond long events of coherent radio emission coming from half way across the Universe. The inferred plasma and radiation conditions are extreme: radio waves carry macroscopic amount of energy, the laser non-linearity parameter $a_0$ can be as large as millions, the guiding magnetic field may reach critical quantum values. I will highlight plasma challenges of producing high brightness coherent emission in astrophysical surrounding, new regimes of plasma-laser interaction, and discuss how the concept of Free Electron Lasers may help us to understand these mysterious events.https://cassyni-user-files-prod.s3.amazonaws.com/KkEjiKd7rVVX9RMyKtAJnr https://cassyni.com/events/V7okiE5y9DVvERXiEGhghb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DgzEe2HC3fXhSzae84KfYa https://cassyni.com/events/Xb3mweKbLWGQbN1GmxcKRX/abstract https://cassyni.com/events/U8WYcrnvGJPmZfhi8JEMth/abstract https://cassyni.com/events/6tdZdTyMPcaTRuiYFk2Djs/abstract https://cassyni.com/events/7PHAg9csq58WRgFRrBK21B/abstract https://cassyni.com/slides/outline/Bp3wkNrvUUv9J4T4AP9UZs https://cassyni.com/events/Bp3wkNrvUUv9J4T4AP9UZs/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CUnhJu1PR65WKW5tSTSZKc https://cassyni.com/events/Bp3wkNrvUUv9J4T4AP9UZs?videoPreview=1 Femoral Arterial Access in Pediatric Diagnostic Angiography and Endovascular Interventions: Predictors of Technical Success, Adverse Events and Thrombotic Risknohttps://cassyni.com/events/Bp3wkNrvUUv9J4T4AP9UZs?videoPreview=12025-10-16T09:46:19+00:00605.24Society for Pediatric Interventional Radiology## Introduction To identify predictors of technical success and adverse events (AEs) associated with ultrasound (US)-guided femoral arterial (FA) access in children undergoing diagnostic angiography and interventions. ## Materials and Methods Retrospective study including consecutive FA access attempts aged ≤18 years at a tertiary pediatric hospital between January 2018 and December 2024. Baseline demographics, corrected FA diameter and technical details were analysed using univariable and multivariable Firth logistic regression to identify predictors of technical success and AEs. ## Results 661 US-guided FA access were attempted in 311 patients. Median age was 7.9 years (range, 0.09–17.9), and median corrected FA diameter was 4.6 mm (range, 1.2–9.6). 49.8% (329/661) accesses were for interventions. Technical success was 99.2% (656/661). The overall AE rate was 5.4% (36/661), with 1.7% (11/661) SIR moderate and severe grades. Vasospasm, more common in arteries ≤3.9 mm, was associated with both access failure and thrombosis. Prophylactic intra-arterial nitroglycerin significantly reduced vasospasm risk (P < .001). Arterial thrombosis occurred in 0.9% (6/661) of accesses, with median age of 0.3 years, weight of 6.4 kg and corrected FA diameter of 1.7mm. All cases were managed anticoagulation, with no permanent ischemic sequelae. Independent predictors of thrombosis included sheath-to-artery (S/A) ratio ≥1 (P<.001) and use of vascular closure device (VCD) (P=.02). Hematoma was associated with ≥6 French sheath and body weight ≥75 kg (P<.001). ## Discussion US-guided FA access has a high success and low AE rate in children. Pre-procedural US assessment, careful sheath selection and prophylactic intra-arterial nitroglycerin can help improve outcome. VCD should be used with caution in children.https://cassyni-user-files-prod.s3.amazonaws.com/CUnhJu1PR65WKW5tSTSZKc https://cassyni.com/slides/outline/EJF8sCcgN3BPLt3F3BjWrZ https://cassyni.com/events/EJF8sCcgN3BPLt3F3BjWrZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Sz4qQwpANmac4UVfystupJ https://cassyni.com/events/EJF8sCcgN3BPLt3F3BjWrZ?videoPreview=1 Gender Equality in Times of Conflict: Violence, Human Rights and Peacekeepingnohttps://cassyni.com/events/EJF8sCcgN3BPLt3F3BjWrZ?videoPreview=12022-09-21T14:00:00+00:005392.56Springer Nature Sustainable Development Goals ProgrammeSpringer Nature is proud to host a virtual event that brings together four scholars and practitioners across different regions to speak on gender equality in times of conflict. Coinciding with the International Day of Peace, we aim for this panel to highlight the impact of conflict on gender-based violence, and vice versa; how conflict affects the struggle for women's rights; and women's role in peacekeeping. This webinar will be held at 7am PDT, 10am EDT, 3pm BST, 7:30pm IST, 10pm CSThttps://cassyni-user-files-prod.s3.amazonaws.com/Sz4qQwpANmac4UVfystupJ https://cassyni.com/slides/outline/Bq17dnP4AkQrJioTaPw9rM https://cassyni.com/events/Bq17dnP4AkQrJioTaPw9rM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4xPwNJj3vu8twWRYTeejMQ https://cassyni.com/events/Bq17dnP4AkQrJioTaPw9rM?videoPreview=1 Advancements of Data Assimilation Techniques for PIVnohttps://cassyni.com/events/Bq17dnP4AkQrJioTaPw9rM?videoPreview=12022-04-12T14:00:00+00:001898.48Experiments in FluidsThe seminar covers advancements of methods for PIV data assimilation obtained in the past-decade. The topic is split into two main chapters. The first is entitled: pouring space in time. In this part, data-assimilation is presented with its ability to forecast the fluid flow state from a given observation (measurement). In the context of PIV such techniques aim at time-supersampling. Two models, of increasing complexity and generality are presented: local advection of velocity and vorticity transport equation, respectively. It is shown that for spatially distributed data, respecting Nyquist principle is not required, as the time-history of the flow can be reconstructed from samples taken at relatively low-frequency. The second chapter is entitled: pouring time in space. Here we focus on the ability of data assimilation to perform physically informed interpolation. The method of choice to include governing laws makes use again of the vorticity transport equation with the vortex-in-cell numerical algorithm. It is shown that using spatially sparse velocity and acceleration, as produced by time-resolved particle tracking (e.g. Shake-the-Box) yields increased spatial resolution, compared to traditional cross-correlation analysis used in Tomographic PIV. The application to experiments in a turbulent boundary layer demonstrates the increase in resolution returning accurate estimates of turbulent dissipation. The last part of the talk is dedicated to a relatively recent development, namely the time segment assimilation approach to vortex-in-cell (TSA-VIC). In this method, the optimisation of the cost function built upon the disparity between observations and model calculations, include measurements encompassing a finite time interval. The application to the cylinder turbulent wake shows how the length of such time segment plays a role in the accuracy of the result, in terms of noise and spatial resolution.https://cassyni-user-files-prod.s3.amazonaws.com/4xPwNJj3vu8twWRYTeejMQ https://cassyni.com/events/QAnt5Rpt6nMozw1QJPovJ1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6bBJ8KzLZAf8WqfPxVyg8n https://cassyni.com/events/Se4XRUaPhS4Pv7H9TTnptm/seminar/qa https://cassyni.com/slides/outline/Se4XRUaPhS4Pv7H9TTnptm https://cassyni.com/events/Se4XRUaPhS4Pv7H9TTnptm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/H9PmHe5i6szZyetgc1fyS6 https://cassyni.com/slides/outline/JjfEZui7GkGjc4mAhUp8JZ https://cassyni.com/events/JjfEZui7GkGjc4mAhUp8JZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AeiUp2rX9CrzNpP8LqDFPk https://cassyni.com/events/JjfEZui7GkGjc4mAhUp8JZ?videoPreview=1 Stability of flow in a 90-degree bendnohttps://cassyni.com/events/JjfEZui7GkGjc4mAhUp8JZ?videoPreview=12022-09-13T15:30:00+00:00717.08NEKTAR++The presentation describes stability of two-dimensional flow in a channel that consists of straight inlet and outlet branches and a circular 90-degree curved bend. An incompressible viscous fluid flows through the elbow under the action of a constant pressure gradient between the inlet and outlet. Navier-Stokes equations were solved numerically using a high-fidelity spectral/hp element method. In a range of Reynolds numbers, an adaptive selective frequency damping method was used to get steady-state flow. It was found that three separation bubbles and vortex shedding can exist in the bend. The modal stability of two- and three-dimensional perturbations was investigated. The critical Reynolds number of the two-dimensional disturbances was found by extrapolation from lower Reynolds number results. It is much greater than the three-dimensional one, but the two-dimensional flow could be subcritically unstable with respect to the externally imposed small-amplitude white noise. For three-dimensional perturbations, the dependence of the critical Reynolds numbers on the bending radius was obtained. For the case of a moderate bending radius, a neutral curve is provided and eigenfunctions are studied in detail. Three-dimensional instability can be caused by a periodic or monotonically growing mode, and these unstable modes relate to the recirculation bubbles that occur after the bend.https://cassyni-user-files-prod.s3.amazonaws.com/AeiUp2rX9CrzNpP8LqDFPk https://cassyni.com/events/FmoEQSLr3MsTddptgudr9B/seminar/qa https://cassyni.com/slides/outline/FmoEQSLr3MsTddptgudr9B https://cassyni.com/events/FmoEQSLr3MsTddptgudr9B/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WyoV1TBK3eCg7zK2gom3qQ https://cassyni.com/events/FmoEQSLr3MsTddptgudr9B?videoPreview=1 Vascular Access Radiology and Surgerynohttps://cassyni.com/events/FmoEQSLr3MsTddptgudr9B?videoPreview=12023-03-09T14:00:00+00:007441.56Dialysis GroupAn overview of how the role of vascular duplex studies fits within the Vascular Access MDT, the role of surveillance imaging and its uses in helping to treat dysfunctional fistulas. The role of Interventional Radiology in the Access MDT will also be outlined and an overview of treatments available within the IR suite. This talk relates to the planning and complexities (and not!) of vascular access planning. I will also touch on new technologies and their place in dialysis patients accesshttps://cassyni-user-files-prod.s3.amazonaws.com/WyoV1TBK3eCg7zK2gom3qQ https://cassyni.com/slides/outline/VbvXawwevpTD8LbCK23pFP https://cassyni.com/events/VbvXawwevpTD8LbCK23pFP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3e9KAB82DJVKeh9qdUqcJi https://cassyni.com/events/VbvXawwevpTD8LbCK23pFP?videoPreview=1 Beyond Eloquence and on to Centrality: A new paradigm in planning supratentorial brain surgerynohttps://cassyni.com/events/VbvXawwevpTD8LbCK23pFP?videoPreview=12022-09-19T19:00:00+00:001789.84Journal of Neuro-OncologyThis webinar focuses on connectomics and how to make neurosurgery safer.https://cassyni-user-files-prod.s3.amazonaws.com/3e9KAB82DJVKeh9qdUqcJi https://cassyni.com/slides/outline/S9PJGAQyrcaa6eHdfMfriZ https://cassyni.com/events/S9PJGAQyrcaa6eHdfMfriZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RA9jaE7oCbLHfWHH6p33Xk https://cassyni.com/events/S9PJGAQyrcaa6eHdfMfriZ?videoPreview=1 Leonardi.DB: A Database of Aristotelian Diagramsnohttps://cassyni.com/events/S9PJGAQyrcaa6eHdfMfriZ?videoPreview=12022-10-19T14:00:00+00:004656.72Logica UniversalisAristotelian diagrams, such as the square of opposition, are among the oldest and most well-known types of logical diagrams. Within the burgeoning research program of logical geometry, we have been developing a comprehensive database of Aristotelian diagrams that occur in the extant literature: Leonardi.DB (the Leuven Ontology for Aristotelian Diagrams, and its corresponding Database). In this talk, which is based on joint work with Hans Smessaert, I will present Leonardi.DB to the universal logic research community. We describe the philosophical background and main motivations for Leonardi.DB, focusing on how the database provides a solid empirical foundation for theoretical research within logical geometry. We also discuss some of the main methodological and technical aspects of the database development. As a proof-of-concept, we provide some examples of the new kinds of research that will be facilitated by Leonardi.DB, e.g., regarding broad trends in the usage and visual properties of Aristotelian diagrams.https://cassyni-user-files-prod.s3.amazonaws.com/RA9jaE7oCbLHfWHH6p33Xk https://cassyni.com/slides/outline/4QriE5wtYUDAHu1MHGHC29 https://cassyni.com/events/4QriE5wtYUDAHu1MHGHC29/abstract https://cassyni-user-files-prod.s3.amazonaws.com/M6abf7FucYRMMZFagK8Bnn https://cassyni.com/events/4QriE5wtYUDAHu1MHGHC29?videoPreview=1 Droplets of Yield Stress Fluidsnohttps://cassyni.com/events/4QriE5wtYUDAHu1MHGHC29?videoPreview=12021-05-07T15:00:00+00:002413.48Journal of Fluid MechanicsThe impact and spreading of droplets of complex fluids over surfaces occur in a variety of industrial applications. We will study the spreading of viscoplastic droplets under surface tension and gravity. The droplet converges to a final equilibrium shape once the driving stresses inside the droplet fall below the yield stress. Scaling laws are presented for the final radius and complemented with an asymptotic analysis for shallow droplets. Moreover, numerical simulations using the volume-of-fluid method and a regularized constitutive law and experiments with an aqueous solution of Carbopol are presented. In the end, we briefly present the other applications of droplets of yield stress fluids.https://cassyni-user-files-prod.s3.amazonaws.com/M6abf7FucYRMMZFagK8Bnn https://cassyni.com/slides/outline/EnUQCSXum5qapQJVJNE5hf https://cassyni.com/events/EnUQCSXum5qapQJVJNE5hf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GX48Cq5Pvu5WoFGpfsRLEa https://cassyni.com/events/EnUQCSXum5qapQJVJNE5hf?videoPreview=1 Controlling the angular memory effect through diffusive medianohttps://cassyni.com/events/EnUQCSXum5qapQJVJNE5hf?videoPreview=12022-07-04T10:10:00+00:001232.04ETOPIMThe angular memory effect led to a paradigm shift in imaging through diffusive media by harnessing the spatial information from the multiply scattered or diffused light. However, it has certain constraints such as finite angular correlation range and predetermined direction that correlations are observed. Here, we propose and experimentally demonstrate a general approach to arbitrarily control the angular memory effect in diffusive media. Introducing an angular memory operator by applying a certain transformation to the field transmission matrix, we show that the eigenvectors of such an operator have perfect “memory” for arbitrarily chosen angles and tilt directions of input and output wavefronts. Our work paves the way to customize the memory effect of both classical and quantum waves for imaging, metrology, and communication applications in complex scattering systems.https://cassyni-user-files-prod.s3.amazonaws.com/GX48Cq5Pvu5WoFGpfsRLEa https://cassyni.com/slides/outline/FkzB6BQ9Mu1PMfYLfa9iEy https://cassyni.com/events/FkzB6BQ9Mu1PMfYLfa9iEy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/ME1nhJbAAocRiJV6fHympA https://cassyni.com/events/FkzB6BQ9Mu1PMfYLfa9iEy?videoPreview=1 Science Advocacy in Action: New Insights into Arterivirusnohttps://cassyni.com/events/FkzB6BQ9Mu1PMfYLfa9iEy?videoPreview=12025-11-18T06:00:00+00:00880.64Journal of VirologyEven within well-studied viruses, there are still hidden stories waiting to be told. In this featured Journal of Virology® Seminar Series talk, Dr. Adam Bailey shares how his lab’s recent work on arteriviruses—+ssRNA-enveloped viruses within the Nidovirales order—reveals new details about receptor usage, tissue tropism, and viral persistence. By investigating how arteriviruses interact with their hosts, Dr. Bailey’s team is helping to illuminate the fundamental principles that govern viral transmission, immune evasion, and cross-species infection. These discoveries not only advance our understanding of a lesser-known virus family but also strengthen the foundation for responding to future zoonotic threats—reminding us that even the smallest discoveries can reshape how we understand the microbial world. https://cassyni-user-files-prod.s3.amazonaws.com/ME1nhJbAAocRiJV6fHympA https://cassyni.com/slides/outline/FH81F8BSCYPdpAqNtoWsxy https://cassyni.com/events/FH81F8BSCYPdpAqNtoWsxy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8DpqE3qBtSMViL5zmEZ2T8 https://cassyni.com/events/FH81F8BSCYPdpAqNtoWsxy?videoPreview=1 Effective models for space-coiled metasurfacesnohttps://cassyni.com/events/FH81F8BSCYPdpAqNtoWsxy?videoPreview=12022-07-05T15:20:00+00:001106.04ETOPIMWe study two families of transmissive metasurfaces based on so-called space-coiled or labyrinthine structures. We show that these two families which differ by their winding arrangements have very different resonant mechanisms and we provide effective models which are derived thanks to asymptotic analysis.https://cassyni-user-files-prod.s3.amazonaws.com/8DpqE3qBtSMViL5zmEZ2T8 https://cassyni.com/events/CKG15epAy9zpbwXL3FFtcM/seminar/qa https://cassyni.com/slides/outline/CKG15epAy9zpbwXL3FFtcM https://cassyni.com/events/CKG15epAy9zpbwXL3FFtcM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6ux6TT2DAnixhVgoSVEgyC https://cassyni.com/events/CKG15epAy9zpbwXL3FFtcM?videoPreview=1 Prediction of Wave Localization in 2D Disordered Vibrating Systemsnohttps://cassyni.com/events/CKG15epAy9zpbwXL3FFtcM?videoPreview=12023-05-02T13:00:00+00:003613.64MetaMATAs a general physical phenomenon, localized waves have been studied in optics, electromagnetism, acoustics and many physical domains. Strong or Anderson localization and weakly localized waves have special attention in optics and in quantum mechanics, due to the disordered media, but also can be found in mechanical waves. In this seminar, I will present results about several systems displaying wave localization in the field of vibrations. When the localization is produced by complex boundary conditions, the landscape of localization theory allows to predict the position and frequency of the localized modes. Experimental results demonstrate that it is possible to obtain this information from a simple static deformation measurement, without knowing precisely the details of the geometry or physical properties [1,2]. Another way to stimulate localization is to create a dense assembly of scatterers, or use a quasi-periodical structure. We investigate localization properties of an elastic plate with closely disposed non-through holes, as resonating scatterers. The measurement of the wavefield in the full plate and the scatterers themselves reveals specific properties of the localized modes. https://cassyni-user-files-prod.s3.amazonaws.com/6ux6TT2DAnixhVgoSVEgyC https://cassyni.com/slides/outline/9qzMjc4fNWJZRJb9HtX5yX https://cassyni.com/events/9qzMjc4fNWJZRJb9HtX5yX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RkFhy6Ui1cZ5PYDecZDnKx https://cassyni.com/events/9qzMjc4fNWJZRJb9HtX5yX?videoPreview=1 Optimal reconstruction of the material immittance response from a small number of noisy measurementsnohttps://cassyni.com/events/9qzMjc4fNWJZRJb9HtX5yX?videoPreview=12022-07-07T13:40:00+00:001373.04ETOPIMFrequency-dependent material response to an electromagnetic field, complex impedance of electrochemical systems, and effective moduli of composites as functions of the properties of constituent materials can all be expressed in terms of complex analytic functions of Stieltjes class. In fact, any passive, linear, time-invariant system admits such a description. A new definitive algorithm of optimal reconstruction of Stieltjes functions is presented. The main distinguishing feature of the new algorithm is that it presents the certificate of optimality of the underlying least squares problem.https://cassyni-user-files-prod.s3.amazonaws.com/RkFhy6Ui1cZ5PYDecZDnKx https://cassyni.com/slides/outline/NCE61KkfkK59TTXMYp2FkH https://cassyni.com/events/NCE61KkfkK59TTXMYp2FkH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/85a6CRLWFjdKZiycFukhLz https://cassyni.com/events/NCE61KkfkK59TTXMYp2FkH?videoPreview=1 Different Strokes For Different Folks; Or, How I Learned To Stop Worrying And Love Writing Papersnohttps://cassyni.com/events/NCE61KkfkK59TTXMYp2FkH?videoPreview=12022-11-08T03:00:00+00:003192.36The Auckland Bioengineering InstituteThis presentation will primarily concern the research contained within the thesis "Different Strokes For Different Folks: Patient-Specific Gait Modelling and Post-Stroke Rehabilitation," found on ResearchSpace. It will also, however, serve as a semi-autobiographical mostly-factual mildly-self-indulgent recount of my experience doing a PhD at the ABI. Articles that will be discussed involve validating shape-model-based musculoskeletal models, alternative motion capture fitting procedures, novel haptic biofeedback for stroke rehabilitation, and generation of synthetic data. Memories that may be discussed involve degree conversions, filmmaking, writing, and soul-searching. And coffee. Lots of that.https://cassyni-user-files-prod.s3.amazonaws.com/85a6CRLWFjdKZiycFukhLz https://cassyni.com/slides/outline/QfU7EjzHwbqdpPzv6VvtUD https://cassyni.com/events/QfU7EjzHwbqdpPzv6VvtUD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Nx1cafw8G1VidG7Fb5ZALE https://cassyni.com/events/QfU7EjzHwbqdpPzv6VvtUD?videoPreview=1 Rates of mixing in models of fluid devices with discontinuitiesnohttps://cassyni.com/events/QfU7EjzHwbqdpPzv6VvtUD?videoPreview=12020-11-27T16:00:00+00:001124.72Journal of Fluid MechanicsThe dynamics of mixing by cutting and shuffling are subtle and not well understood. We present mixing dynamics arising from fundamental models capturing the essence of discontinuous stirring with diffusion. When the stirring is governed by purely cutting and shuffling, we reveal that the time to achieve a mixed condition varies polynomially with diffusivity rate with an exponent less than unity. In stirring fields which are chaotic we observe that the addition of discontinuous transformations contaminates mixing. Long-time mixing rates behave counter-intuitively when varying the diffusivity rate and a deceleration of mixing with increasing diffusion coefficient is observed, sometimes overshooting analytically derived bounds. https://cassyni-user-files-prod.s3.amazonaws.com/Nx1cafw8G1VidG7Fb5ZALE https://cassyni.com/slides/outline/Kiz4muX3Z2JcRJHa62Dtk5 https://cassyni.com/events/Kiz4muX3Z2JcRJHa62Dtk5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4FxKU2gRm8BVR9XxBWCzmU https://cassyni.com/events/Kiz4muX3Z2JcRJHa62Dtk5?videoPreview=1 Racial disparities in pediatric malignant glioma management: current state of affairs in the United Statesnohttps://cassyni.com/events/Kiz4muX3Z2JcRJHa62Dtk5?videoPreview=12022-11-14T21:00:00+00:001585.4Journal of Neuro-OncologyOn this episode of Tumor Talk, Dr. Randy D'Amico and Dr. Jason Sheehan discuss the racial disparities in pediatric malignant glioma management with University of Miami/Jackson Health System Neurosurgical Resident, Dr. Victor Lu, Pediatric Neurosurgeon and Medical Director of Neuro-Oncology Surgical Services at Nicklaus Children's Hospital, Dr. Toba Niazi, and Neurologic Surgery Residency at the Mayo Clinic School of Graduate Medical Education, Dr. Cody Nesvick.https://cassyni-user-files-prod.s3.amazonaws.com/4FxKU2gRm8BVR9XxBWCzmU https://cassyni.com/slides/outline/AKt9hHoFwDr5nVkjGKz6AR https://cassyni.com/events/AKt9hHoFwDr5nVkjGKz6AR/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TzkW5AWQQhLP8QXDCwtDU https://cassyni.com/events/AKt9hHoFwDr5nVkjGKz6AR?videoPreview=1 Hantaviruses in the Wild: True-to-Nature Models of Infection in Reservoir Rodentsnohttps://cassyni.com/events/AKt9hHoFwDr5nVkjGKz6AR?videoPreview=12026-06-23T13:00:00+00:003489.52Journal of VirologyJoin us for the next Journal of Virology Seminar Series where Jason Botten, Ph.D. and Rebekah Honce, Ph.D. will discuss the ecology and natural history of orthohantavirus infection in reservoir rodents, with an emphasis on the North American Sin Nombre virus, which can cause hantavirus cardiopulmonary syndrome (HCPS) in humans. Orthohantaviruses are enveloped, negative-strand RNA viruses that are maintained in nature in rodents where they are thought to establish life-long, asymptomatic infections. This webinar will outline approaches to study the infection process in reservoir animals, including the development of near-natural infection models featuring wild rodents and matched infectious virus isolates obtained from those same wild populations. To illustrate how this can be done, the presenters will revisit the nontraditional approach used to establish the first experimental model of Sin Nombre virus infection in its reservoir, the deer mouse and discuss key findings from that model. The presentation will close with a summary of knowledge regarding the natural history of infection of other orthohantaviruses as well as mammarenaviruses in their respective reservoir hosts and a discussion of key gaps in knowledge and opportunities for the field. Key Learning Objectives: Understand what rodent-borne orthohantaviruses and mammarenaviruses are. Understand the infection process of Sin Nombre virus in its reservoir, the deer mouse. Understand the approaches available to study rodent-borne virus infection in natural reservoir rodents, including their strengths and limitations. Learn the key gaps in knowledge regarding our understanding of infection in reservoir animals and opportunities available to address these key questions.https://cassyni-user-files-prod.s3.amazonaws.com/TzkW5AWQQhLP8QXDCwtDU https://cassyni.com/events/6PXzki5eWPCjRHH1B7pd6M/seminar/qa https://cassyni.com/slides/outline/6PXzki5eWPCjRHH1B7pd6M https://cassyni.com/events/6PXzki5eWPCjRHH1B7pd6M/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DYWLQKUu6oWXD53boCKVTC https://cassyni.com/events/6PXzki5eWPCjRHH1B7pd6M?videoPreview=1 Applicationsnohttps://cassyni.com/events/6PXzki5eWPCjRHH1B7pd6M?videoPreview=12023-06-14T08:00:00+00:003633.68NEKTAR++Project NEPTUNE (NEutrals and Plasma Turbulence Numerics for the Exascale; part of the UK's ExCALIBUR programme) aims to provide fusion plasma simulation capability compatible with the coming landscape of exascale-class hardware, focussing in particular on the `edge' region of the plasma where it comes into contact with the material of the tokamak. This represents an extremely challenging problem, particularly in view of the need to use kinetic theory where the plasma is not in local thermal equilibrium (though equilibrium fluids must be used where possible in order to manage computational expense). The plasma fluid component of NEPTUNE is expected to be a set of solvers built on Nektar++, treating the equations of motion for a charged, multicomponent, and strongly magnetized fluid, and leveraging the advantages of the spectral / hp method over existing finite-difference plasma codes. The non-equilibrium matter is treated using a particle simulation code developed in-house by the NEPTUNE team, which interfaces with, and in particular is able to leverage the meshing capabilities of, Nektar++. This talk will explain the rationale and structure of code developed under Project NEPTUNE and will outline current work toward coupled 3D plasma turbulence, neutral kinetics, and atomic reactions capability. Work toward true performance portability will be shown, with SYCL as the chosen DSL and including SYCL implementation of some existing Nektar++ code. The support of the UK Meteorological Office and Strategic Priorities Fund is acknowledged. Much attention has been paid to deep learning and machine learning techniques to reduce the computational cost of computational fluid dynamics simulations. This work addresses the prediction of steady-state flows through many stationary cylinders using a deep-learning model and examines the accuracy of the predicted velocity fields. A deep learning model predicts the x and y components of the velocity field for a given cylinder configuration. The accuracy of the predicted velocity field is investigated with a focus on the velocity profile of the fluid flow and the fluid forces acting on the cylinder. This research focuses on the flow around a large number of cylinders and consists of the following two studies. The first of two studies in this study predicted a steady flow through a stationary cylinder, which is reported in this study. In this study, all cylinders are considered immobile and fixed in space. Fluid flow is guided by boundary conditions. In this research, we use a U-Net-like architecture to build a deep learning model. U-Net is typically applied to image segmentation problems. However, in this research, we apply U-Net to physical problems. Examine the accuracy of the predicted velocity field associated with the velocity profile of the fluid flow and the fluid forces acting on the cylinder. The current model accurately predicts flow when the number of cylinders is equal to or close to the number in the training data set. Extrapolating the predictions to a smaller number of cylinders introduces an error that can be interpreted as internal friction in the fluid. The fluid force results acting on cylinders suggest that the current deep learning model has good generalization performance for systems with a large number of cylinders. This study will help in designing the wind turbine arrangements for achieving the optimal power output for a given flow condition.https://cassyni-user-files-prod.s3.amazonaws.com/DYWLQKUu6oWXD53boCKVTC https://cassyni.com/slides/outline/T8i8UADv8tcSusp33u5dA5 https://cassyni.com/events/T8i8UADv8tcSusp33u5dA5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TZfqMRZsqqUGUFp2mHW4nz https://cassyni.com/events/T8i8UADv8tcSusp33u5dA5?videoPreview=1 Learning Homogenized PDEs in Continuum Mechanicsnohttps://cassyni.com/events/T8i8UADv8tcSusp33u5dA5?videoPreview=12022-01-27T16:00:00+00:003223.52DataSıgNeural networks have shown great success at learning function approximators between spaces X and Y, in the setting where X is a finite dimensional Euclidean space and where Y is either a finite dimensional Euclidean space (regression) or a set of finite cardinality (classification); the neural networks learn the approximator from N data pairs {x_n, y_n}. In many problems arising in the physical and engineering sciences it is desirable to generalize this setting to learn operators between spaces of functions X and Y. The talk will overview recent work in this context. Then the talk will focus on work aimed at addressing the problem of learning operators which define the constitutive model characterizing the macroscopic behaviour of multiscale materials arising in material modeling. Mathematically this corresponds to using machine learning to determine appropriate homogenized equations, using data generated at the microscopic scale. Applications to visco-elasticity and crystal-plasticity are given.https://cassyni-user-files-prod.s3.amazonaws.com/TZfqMRZsqqUGUFp2mHW4nz https://cassyni.com/slides/outline/4uXwPQ7JPHgz7Mzs5NQACM https://cassyni.com/events/4uXwPQ7JPHgz7Mzs5NQACM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AMpNfoTovrspRdHQRJ6chC https://cassyni.com/events/4uXwPQ7JPHgz7Mzs5NQACM?videoPreview=1 Neural Networks for Learning Control Lawsnohttps://cassyni.com/events/4uXwPQ7JPHgz7Mzs5NQACM?videoPreview=12021-02-19T12:00:00+00:001274.84Brunton Lab In this video, we provide an overview of developments in deep reinforcement learning, along with leading algorithms and impressive applications.https://cassyni-user-files-prod.s3.amazonaws.com/AMpNfoTovrspRdHQRJ6chC https://cassyni.com/slides/outline/DJZDB27Dr56yGhML9DjDRF https://cassyni.com/events/DJZDB27Dr56yGhML9DjDRF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/N1NnajYDuSEqvbuTdGy3Ci https://cassyni.com/events/DJZDB27Dr56yGhML9DjDRF?videoPreview=1 Tropical time series, iterated-sums signatures and quasisymmetric functionsnohttps://cassyni.com/events/DJZDB27Dr56yGhML9DjDRF?videoPreview=12020-10-01T16:00:00+00:003577.88DataSıgDriven by the need for principled extraction of features from time series, we introduce the iterated-sums signature over any commutative semiring. The case of the tropical semiring is a central, and our motivating, example, as it leads to features of (real-valued) time series that are not easily available using existing signature-type objects. This is joint work with Kurusch Ebrahimi-Fard (NTNU Trondheim) and Nikolas Tapia (WIAS Berlin).https://cassyni-user-files-prod.s3.amazonaws.com/N1NnajYDuSEqvbuTdGy3Ci https://cassyni.com/events/4QzpoEXKZGqo2b5CfwajQR/seminar/qa https://cassyni.com/slides/outline/4QzpoEXKZGqo2b5CfwajQR https://cassyni.com/events/4QzpoEXKZGqo2b5CfwajQR/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UrFo9HYCTw5UzA36BhiiGE https://cassyni.com/events/4QzpoEXKZGqo2b5CfwajQR?videoPreview=1 Wave propagation in quasiperiodic medianohttps://cassyni.com/events/4QzpoEXKZGqo2b5CfwajQR?videoPreview=12024-01-16T14:00:00+00:005638.16MetaMATA quasiperiodic medium is an ordered medium without being periodic. A fairly well-known example since the 2011 Nobel Prize in Chemistry is the quasicrystal. The notion of quasi-periodic and more generally almost periodic function is a very well-defined notion in the mathematical literature. To give an idea, a 1D quasiperiodic function is the trace along a line of a periodic function of $n$ variables. PDEs with quasi-periodic coefficients have been the subject of a number of theoretical studies, but it seems that there has been much less work on the numerical resolution of these equations. The objective of this work is to develop original numerical methods for the resolution of the time-harmonic wave equation in quasiperiodic media, in the spirit of the methods previously developed for periodic media. The idea is to use the fact that the study of an elliptic PDE with quasiperiodic coefficients comes down to the study of an "augmented" non-elliptic PDE in higher dimensions, but whose coefficients are periodic. This so-called lifting approach allows to use tools that are adapted for periodic media, but comes with the price that the augmented PDE is non-elliptic, in the sense of its principal part. In this talk, I will first present the lifting method for the 1D Helmholtz equation with dissipation. I will then explain how this method can be used to solve the 2D Helmholtz equation in a junction of periodic media cut in an arbitrary direction. The method will be illustrated by numerical results. https://cassyni-user-files-prod.s3.amazonaws.com/UrFo9HYCTw5UzA36BhiiGE https://cassyni.com/events/VceiZKLhQCY6vkhdjnTJfX/seminar/qa https://cassyni.com/slides/outline/VceiZKLhQCY6vkhdjnTJfX https://cassyni.com/events/VceiZKLhQCY6vkhdjnTJfX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CN3ycbkEEjcFCNRwZ6rsvW https://cassyni.com/events/VceiZKLhQCY6vkhdjnTJfX?videoPreview=1 Solitary wave interactions modelled using conserved and empirically conserved quantities discovered with machine learningnohttps://cassyni.com/events/VceiZKLhQCY6vkhdjnTJfX?videoPreview=12025-07-18T09:00:00+00:003075.12Royal Society PublishingConservation laws play an important role in analysing physical systems and solving partial differential equations (PDEs). In this paper, we use associated conserved quantities (CQs) to construct a simple and robust way to approximate the interaction between surface solitary waves—a common nonlinear phenomenon in many research fields and engineering applications. One major constraint of such an approach is how many CQs are available from the governing equation. In this study, we start with the Korteweg–De Vries (KdV) equation, which has an infinite number of CQs. We show that these CQs can be used to predict soliton interaction accurately. The regularized long wave (RLW) equation—an equivalent reduction form to the KdV equation, however, has insufficient CQs to apply the approach. To address this problem, we use a new symbolic-based machine learning (ML) approach to search for any higher-order empirically CQs (e-CQs), which allow the proposed approach to be applied directly to the RLW equations and leverages the constraints on the number of CQs available. This opens a new opportunity for more complex systems governed by a variety range of PDEs to be modelled with such a CQ-based approach.https://cassyni-user-files-prod.s3.amazonaws.com/CN3ycbkEEjcFCNRwZ6rsvW https://cassyni.com/slides/outline/T9SKSXcxcGhLiHvUUfV7aD https://cassyni.com/events/T9SKSXcxcGhLiHvUUfV7aD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8KUiZiAtENu9MrKFmJC4nz https://cassyni.com/events/T9SKSXcxcGhLiHvUUfV7aD?videoPreview=1 Exascale Geostatistics for Environmental Data Sciencenohttps://cassyni.com/events/T9SKSXcxcGhLiHvUUfV7aD?videoPreview=12024-10-17T12:00:00+00:002941.08MOX Laboratory - Department of MathematicsEnvironmental data science relies on some fundamental problems such as: 1) Spatial Gaussian likelihood inference; 2) Spatial kriging; 3) Gaussian random field simulations; 4) Multivariate Gaussian probabilities; and 5) Robust inference for spatial data. These problems develop into very challenging tasks when the number of spatial locations grows large. Moreover, they are the cornerstone of more sophisticated procedures involving non-Gaussian distributions, multivariate random fields, or space-time processes. Parallel computing becomes necessary for avoiding computational and memory restrictions associated with large-scale environmental data science applications. In this talk, I will explain how high-performance computing can provide solutions to the aforementioned problems using tile-based linear algebra, tile low-rank approximations, as well as multi- and mixed-precision computational statistics. I will introduce ExaGeoStat, and its R version ExaGeoStatR, a powerful software that can perform exascale (10^18 flops/s) geostatistics by exploiting the power of existing parallel computing hardware systems, such as shared-memory, possibly equipped with GPUs, and distributed-memory systems, i.e., supercomputers. I will then describe how ExaGeoStat can be used to design competitions on spatial statistics for large datasets and to benchmark new methods developed by statisticians and data scientists for large-scale environmental data science. This initiative is part of the “Ph.D. Lectures” activity of the project "Departments of Excellence 2023-2027" of the Department of Mathematics of Politecnico di Milano. This activity consists of seminars open to Ph.D. students, followed by meetings with the speaker to discuss and go into detail on the topics presented at the talk.https://cassyni-user-files-prod.s3.amazonaws.com/8KUiZiAtENu9MrKFmJC4nz https://cassyni.com/events/FnXRNojtWjxMS3wL7g3LZK/seminar/qa https://cassyni.com/slides/outline/FnXRNojtWjxMS3wL7g3LZK https://cassyni.com/events/FnXRNojtWjxMS3wL7g3LZK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KyPWRMVwS5HUSScRpNg49U https://cassyni.com/events/FnXRNojtWjxMS3wL7g3LZK?videoPreview=1 Numerical simulations of multiphase flows with various complexitiesnohttps://cassyni.com/events/FnXRNojtWjxMS3wL7g3LZK?videoPreview=12025-06-06T15:00:00+00:003972.04Journal of Fluid MechanicsMultiphase flows are of central importance to a wide range of industrial applications and environmental settings. Examples of these include mixing in stirred vessels and static mixers, flows in micro-channels and microfluidics devices, falling films for CO2 capture, and aerosol formation via bubble bursting through interfaces in the oceans. Some of these flows feature the presence of surface-active agents (surfactants), present either by design or as contaminants. Furthermore, multiphase flows are often punctuated by topological transitions related to the coalescence of dispersed drops or bubbles, and the breakup of threads or ligaments. Here, we provide a few examples of interest to the JFM community but focus on drop impact on hydrophobic substrates in the presence of surfactants above the critical micelle concentration. Our model accounts for the spatio-temporal evolution of the surfactants along the interface and within the bulk; the bulk and interfacial species are fully-coupled via sorptive fluxes. Micellar formation and breakup are also accounted for, and the surfactant dynamics are coupled to the flow through the dependence of the surface tension on the local interfacial surfactant concentration. Our numerical procedure is based on the use of a hybrid interface-tracking/level-set approach. The results of our parametric study help identify the various physical mechanisms underlying the observed flow phenomena.https://cassyni-user-files-prod.s3.amazonaws.com/KyPWRMVwS5HUSScRpNg49U https://cassyni.com/events/W7MZqG1zeNwhaDjchQ1myo/seminar/qa https://cassyni.com/slides/outline/W7MZqG1zeNwhaDjchQ1myo https://cassyni.com/events/W7MZqG1zeNwhaDjchQ1myo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WmadPv7PETje23A12xo9SN https://cassyni.com/events/W7MZqG1zeNwhaDjchQ1myo?videoPreview=1 An introduction to Topology in soft and biological matternohttps://cassyni.com/events/W7MZqG1zeNwhaDjchQ1myo?videoPreview=12024-10-25T12:00:00+00:004010.04Physics ReportsThe last years have witnessed remarkable advances in our understanding of the emergence and consequences of topological constraints in biological and soft matter. Examples are abundant in relation to (bio)polymeric systems and range from the characterization of knots in single polymers and proteins to that of whole chromosomes and polymer melts. At the same time, considerable advances have been made in the description of the interplay between topological and physical properties in complex fluids, with the development of techniques that now allow researchers to control the formation of and interaction between defects in diverse classes of liquid crystals. Thanks to technological progress and the integration of experiments with increasingly sophisticated numerical simulations, topological biological and soft matter is a vibrant area of research attracting scientists from a broad range of disciplines. Here we present a comprehensive and coherent introduction to the topological properties of polymers and of continuum materials, highlighting the underlying common aspects concerning the emergence, characterization, and effects of topological objects in different systems. The second half of the talk will be dedicated to the presentation of a selected set of examples including polymer melts, the kinetoplast DNA, a natural 2D topological material made of thousands of interlocked DNA minirings, entangled proteins, and the emergence and effect of topological constraints in complex fluids. https://cassyni-user-files-prod.s3.amazonaws.com/WmadPv7PETje23A12xo9SN https://cassyni.com/slides/outline/Hm9TgAqsfw6qgYVoj3T3qf https://cassyni.com/events/Hm9TgAqsfw6qgYVoj3T3qf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3ypcy8xFA5p5BJLE163d1p https://cassyni.com/events/Hm9TgAqsfw6qgYVoj3T3qf?videoPreview=1 1.1 Basics and Definitions of ScholCommnohttps://cassyni.com/events/Hm9TgAqsfw6qgYVoj3T3qf?videoPreview=12024-10-04T16:00:00+00:002464.68Medical Library Association’s Scholarly Communications CaucusJoin authors Josh Bolick and Will Cross as they discuss Chapter 1.1: Basics and Definitions ScholComm exploring key concepts of scholarly communication, including the creation, evaluation, dissemination, and preservation of scholarly work through both formal and informal channels.https://cassyni-user-files-prod.s3.amazonaws.com/3ypcy8xFA5p5BJLE163d1p https://cassyni.com/events/2whLHfS8WCVDNcD6iPdKHw/seminar/qa https://cassyni.com/slides/outline/2whLHfS8WCVDNcD6iPdKHw https://cassyni.com/events/2whLHfS8WCVDNcD6iPdKHw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/W8DqvKfgFyT2iXgsCxERq8 https://cassyni.com/events/2whLHfS8WCVDNcD6iPdKHw?videoPreview=1 Mitochondria as a target of micro- and nanoplastic toxicitynohttps://cassyni.com/events/2whLHfS8WCVDNcD6iPdKHw?videoPreview=12025-05-14T13:00:00+00:001545.2Cambridge PrismsMitochondria are unique organelles to perform critical functions such as energy production, lipid oxidation, calcium homeostasis, and steroid hormone synthesis in eukaryotic cells. The proper functioning of mitochondria is crucial for cellular survival, homeostasis, and bioenergetics. Mitochondrial structure and function are maintained by the mitochondrial quality control system, which consists of the processes of mitochondrial biogenesis, mitochondrial dynamics (fusion/fission), mitophagy, and mitochondrial unfolded protein response UPRMT. Mitochondrial dysfunction and/or damage is associated with the initiation and progression of several human diseases, including neurodegenerative, cardiovascular, age-related diseases, diabetes, and cancer. Environmental stress and contaminants may exacerbate the sensitivity of mitochondria to damage which causes mitochondrial dysfunction. There is growing evidence about the impact of nanoplastics (NPs) and microplastics (MPs) on mitochondrial health and function. MPs/NPs were reported to trigger oxidative stress and reactive oxygen species production, which eventually change mitochondrial membrane potential. MPs/NPs can cross through the biological barriers in the human body and be internalized by the cells, potentially altering mitochondrial dynamics, bioenergetics, and signaling pathways, thus impacting cellular metabolism and function. This talk states the effects of MPs/NPs on mitochondrial homeostasis and function as well as on mitochondrial membrane dynamics, mitophagy, and mitochondrial apoptosis.https://cassyni-user-files-prod.s3.amazonaws.com/W8DqvKfgFyT2iXgsCxERq8 https://cassyni.com/events/DoxdJhfgAGfgtt38Kvs1Em/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GNvCPBQGrpLqh2G2EZTJQN https://cassyni.com/slides/outline/CpfRDLNdHMZYE8D8DxPgRs https://cassyni.com/events/CpfRDLNdHMZYE8D8DxPgRs/abstract https://cassyni-user-files-prod.s3.amazonaws.com/S5oLaBTzXJTN3AnDecEKUa https://cassyni.com/events/CpfRDLNdHMZYE8D8DxPgRs?videoPreview=1 New Phytologist Now: Stomatanohttps://cassyni.com/events/CpfRDLNdHMZYE8D8DxPgRs?videoPreview=12024-11-26T15:30:00+00:005407.08New PhytologistHeterotrimeric G proteins, composed of Gα, Gβ, and Gγ subunits, are intracellular signaling proteins known to regulate stomatal apertures in response to signals such as ABA and VPD (Wang et al., 2001, Zait et al., 2024). Elevated intercellular CO2 concentrations also engender stomatal closure. However, potential G protein involvement in CO2 sensing has not been investigated, despite substantial recent process in uncovering the signaling network underlying the guard cell CO2 response (Takahashi et al., 2022, Gan et al., 2024). We determined via gas exchange and stomatal aperture measurements that Arabidopsis T-DNA knockouts in the canonical GTP-binding Gα subunit gene, GPA1, are impaired in CO2-induced stomatal closure. Unexpectedly, point mutants of GPA1 that fail to bind or hydrolyze GTP restore CO2-induced stomatal closure in gpa1 null lines. This result implicates other features of GPA1, rather than the classic G protein cycle, in CO2-stimulated signal transduction. We assayed known protein components of the CO2 network for interaction with GPA1 and identified several positive interactors, including the K+ efflux channel, GORK. Our electrophysiological assays in Xenopus oocytes implicate direct ion channel regulation by GPA1 as a key mechanism controlling stomatal apertures in the CO2 response.https://cassyni-user-files-prod.s3.amazonaws.com/S5oLaBTzXJTN3AnDecEKUa https://cassyni.com/events/PgxLM184LnfjtsjZ84Zp1K/seminar/qa https://cassyni.com/slides/outline/PgxLM184LnfjtsjZ84Zp1K https://cassyni.com/events/PgxLM184LnfjtsjZ84Zp1K/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HHPSpN3WbCgidcBXaWgrMk https://cassyni.com/events/PgxLM184LnfjtsjZ84Zp1K?videoPreview=1 Celebrating the First Anniversary of SCNOWnohttps://cassyni.com/events/PgxLM184LnfjtsjZ84Zp1K?videoPreview=12025-01-22T09:00:00+00:009222.0Thieme GroupJoin us for the **Thieme Cheminar: Celebrating the First Anniversary of SCNOW** on January 22nd, 2025. Chaired by Prof. Chris Slootweg, this event will feature insightful talks from Julian Lauten-Weiss, Prof. Anant Kapdi, Prof. Huizhen Liu, and Prof. Silvia Gross, discussing topics such as circular business models, sustainable synthesis, and green materials. Celebrate the achievements of Sustainability & Circularity NOW and discover innovative solutions shaping a more sustainable future.https://cassyni-user-files-prod.s3.amazonaws.com/HHPSpN3WbCgidcBXaWgrMk https://cassyni.com/slides/outline/X6gQ3FpvveyaPTG25wRYRK https://cassyni.com/events/X6gQ3FpvveyaPTG25wRYRK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TfxAxM1mw8PxR1kqsDTeNS https://cassyni.com/events/X6gQ3FpvveyaPTG25wRYRK?videoPreview=1 Learning from K+ channel structure and function - GORK and natural variants from the C4 relative Gynandropsisnohttps://cassyni.com/events/X6gQ3FpvveyaPTG25wRYRK?videoPreview=12024-10-22T12:00:00+00:001864.64The New Phytologist FoundationAs a strategy for water use efficiency and biomass production, accelerating stomata has proven viable through synthetic optogenetics and mutations that enhance guard cell K+ flux. Here I outline some of our discoveries from cryoEM analysis of the Arabidopsis thaliana GORK K+ channel structure. I examine features of GORK gating mutants and the natural variant GROK from the related model C4 species Gynandropsis gynandra. These molecular features contribute to gating, facilitate K+ flux, and speed stomatal movements. Some will clearly translate to crop species to enhance water use efficiency and biomass gains. For GROK, the evidence also speaks to the puzzle of how C4 plant have evolved mechanisms that enhance water use efficiency and growth under stress.https://cassyni-user-files-prod.s3.amazonaws.com/TfxAxM1mw8PxR1kqsDTeNS https://cassyni.com/slides/outline/GHEGekRBkvMx5WyK5Hbosb https://cassyni.com/events/GHEGekRBkvMx5WyK5Hbosb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/67G3yjCa2taMjrbKXTdRyG https://cassyni.com/events/GHEGekRBkvMx5WyK5Hbosb?videoPreview=1 Antibodies And Research Reproducibility: A Technical, Open Data, Behavioural And Policy Challengenohttps://cassyni.com/events/GHEGekRBkvMx5WyK5Hbosb?videoPreview=12023-09-21T03:00:00+00:006710.2UKRNAntibodies are one of the most important tools used in biomedical and fundamental biology research. They are known to be an important driver of irreproducibility in research, with issues around the quality of the reagents, the validation of the reagents for the specific purpose, variation in batches and the transparency of reporting of both methods and results. Although the problem may appear to be simple at first sight, the problem has persisted for more than a decade since it was first highlighted. This has led to some blaming manufacturers, and others blaming “lax” researchers. Like many other reproducibility problems in research, it is likely driven by several complex factors, and an effective solution likely involves changes to the research environment and culture. The Only Good Antibodies (OGA) community was set up to try to address this problem. It is a diverse cross disciplinary collaboration of individuals and partner organisations with interests in biomedical research, behavioural science, meta science, data science and research assessment. This seminar will introduce the problem, primarily with a focus on understanding different models of addressing similar problems throughout research.https://cassyni-user-files-prod.s3.amazonaws.com/67G3yjCa2taMjrbKXTdRyG https://cassyni.com/slides/outline/Ar6d9EJQvtGsgej5UNc1t9 https://cassyni.com/events/Ar6d9EJQvtGsgej5UNc1t9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/F86L5Cku3VgTzRZgEES9Ne https://cassyni.com/events/Ar6d9EJQvtGsgej5UNc1t9?videoPreview=1 Introduction To Causal Inference And Directed Acyclic Graphsnohttps://cassyni.com/events/Ar6d9EJQvtGsgej5UNc1t9?videoPreview=12022-02-03T03:00:00+00:006615.96UKRNLearning objectives: Appreciate ‘description’, ‘prediction’ and ‘causal inference’ as three distinct scientific tasks requiring distinct scientific methods Understand the main features of causal directed acyclic graphs and how they can be used to plan and interpret causal analyses Appreciate some of the challenges and implications of using directed acyclic graphs in applied researchhttps://cassyni-user-files-prod.s3.amazonaws.com/F86L5Cku3VgTzRZgEES9Ne https://cassyni.com/events/BLkEBuwwNLpvgRFy4otp9T/seminar/qa https://cassyni.com/slides/outline/BLkEBuwwNLpvgRFy4otp9T https://cassyni.com/events/BLkEBuwwNLpvgRFy4otp9T/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CybWtteHHqXs83DDdAJQ3x https://cassyni.com/events/BLkEBuwwNLpvgRFy4otp9T?videoPreview=1 LUA World Logic Day 2025 - Logic in All its Dimensionsnohttps://cassyni.com/events/BLkEBuwwNLpvgRFy4otp9T?videoPreview=12025-01-14T15:00:00+00:007274.04Logica UniversalisThe World Logic Day (WLD) was launched in 2019, see: J.-Y.Beziau "1st World Logic Day: 14 January 2019", Logica Universalis, vol.13 (2019), pp.1-20. and was recognized by UNESCO the same year, through the Ambassador of Brazil Maria Edileuza Fontenele Reis, see: "The Inclusion of the World Logic Day in the UNESCO International Days Calendar" This year, for the 7th edition of the WLD, LUA (the Logica Universalis Association) is organizing an on-line round table "Logic in All its Dimensions", a special session of the Logica Universalis Webinar, emphasizing the many aspects and applications of logic. Each participant will speak about 10/15mn and then there will be a general discussion. > Luis Felipe Bartolo Alegre, Munich Center for Mathematical Philosophy at Ludwig Maximilian University of Munich, Germany, Founder and Vice-President of the Peru's Society for Epistemology and Logic (SEPLO), "Logic here, there, and everywhere: the 8th UNILOG in Cusco, Peru, December 2025" > Marcin Trepczyński, Faculty of Philosophy, University of Warsaw, Poland, Member of the Executive Board of the Logic And Religion Association (LARA), "Logic and Religion" > Jasmin Özel, Institute of Philosophy, Paderborn University, Germany and James Woodbridge, Department of Philosophy, University of Nevada, Las Vegas, USA, "Logic, Chance and Money: a new series of events every two years in Las Vegas" > Carolyn Talcott, SRI International, Menlo Park, California, USA, "Logic for Modeling and Design of Diverse Complex Systems" > Sankha Basu, Department of Mathematics, Indraprastha Institute of Information Technology, New Delhi, India, Member of the Logic Society of Delhi, "Logics for Inconsistency Tolerance" > Jean-Yves Beziau. University of Brazil, Rio de Janeiro, President of the Logica Universalis Association (LUA), "Square of Opposition: a Logic Framework with Many Applications" https://cassyni-user-files-prod.s3.amazonaws.com/CybWtteHHqXs83DDdAJQ3x https://cassyni.com/slides/outline/MiPYGu3qzKP5MQFWNUn9Tb https://cassyni.com/events/MiPYGu3qzKP5MQFWNUn9Tb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8cypQxtpb3EJdgVNaW8tWS https://cassyni.com/events/MiPYGu3qzKP5MQFWNUn9Tb?videoPreview=1 (WITHDRAWN) Artificial Intelligence, Scientific Discovery, and Product Innovationnohttps://cassyni.com/events/MiPYGu3qzKP5MQFWNUn9Tb?videoPreview=12025-01-15T16:00:00+00:004177.56Manchester Institute of Innovation Research and Georgia Tech School of Public Policy# Withdrawal notice The MIT Economics department has released an [open letter](https://economics.mit.edu/news/assuring-accurate-research-record) asking for the preprint this seminar discusses to be withdrawn: > Earlier this year, the COD conducted a confidential internal review based upon allegations it received regarding certain aspects of this paper. While student privacy laws and MIT policy prohibit the disclosure of the outcome of this review, we are writing to inform you that MIT has no confidence in the provenance, reliability or validity of the data and has no confidence in the veracity of the research contained in the paper. Based upon this finding, we also believe that the inclusion of this paper in arXiv may violate arXiv’s Code of Conduct.https://cassyni-user-files-prod.s3.amazonaws.com/8cypQxtpb3EJdgVNaW8tWS https://cassyni.com/slides/outline/V87by9kiaBguqymyLMdssb https://cassyni.com/events/V87by9kiaBguqymyLMdssb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XSdm5dujAYwwnipbUn3Rw4 https://cassyni.com/events/V87by9kiaBguqymyLMdssb?videoPreview=1 Beyond Closed Wave Systems: Non-Hermiticity and Nanoscale Casimir Forcenohttps://cassyni.com/events/V87by9kiaBguqymyLMdssb?videoPreview=12025-02-04T16:00:00+00:003188.04MetaMATThe classical wave system has proven to be an excellent platform for realizing novel phenomena that may be challenging to implement in other physical systems experimentally. The bedrocks are macroscopic quantities obtained from the homogenization or mean-field treatment. However, it usually deals with Hermitian problems and averages out fluctuations. Therefore, the presentation will cover two topics: non-Hermitian (NH) physics and mesoscopic Casimir effect. The first part will focus on the spectral topology, which deals with complex energy patterns and their interaction with the wavefunction. I will begin with the order-3 exceptional lines (EL3s) embedded in order-2 exceptional surfaces (ES2s). The eigenvalue winding number becomes poorly defined, so we adopt the resultant manifold to detect only the EL3 but ignore the ES2, which allows the diagnosis of topological currents of the EL3s, enabling the prediction of their evolution under perturbations. Next, I will devote myself to higher-dimensional skin effects (SEs), including geometry-dependent and algebraic SE in mechanics and photonics. Physical understanding and solving the eigenstates will be presented in detail afterward. The second part will discuss nanoscale Casimir force softening from quantum surface responses (QSRs). A three-dimensional conformal mapping method has been established by embedding mesoscopic boundary conditions of electromagnetic fields. It then uncovers that nanoscale Casimir forces are sensitive to the surface electron behavior, and the mechanism results from QSRs effectively alter the distance seen by the Casimir interaction. With such an understanding, a recipe to handle the nanoscale Casimir force between nanoscale complex objects has been provided. https://cassyni-user-files-prod.s3.amazonaws.com/XSdm5dujAYwwnipbUn3Rw4 https://cassyni.com/slides/outline/XbMdCZzLmUTQCvFXt3YWbX https://cassyni.com/events/XbMdCZzLmUTQCvFXt3YWbX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/To7aDWvf3VY2WUqquheWHc https://cassyni.com/events/XbMdCZzLmUTQCvFXt3YWbX?videoPreview=1 Factors driving the community composition of arbuscular mycorrhizal fungi in crop roots can determine plant benefitsnohttps://cassyni.com/events/XbMdCZzLmUTQCvFXt3YWbX?videoPreview=12024-08-12T12:00:00+00:001123.12The New Phytologist FoundationThe application of synthetic fertilisers and pesticides has significantly enhanced the productiviy of agricultural systems, ensuring that crops receive essential nutrients and experience minimal damage from pests and diseases. However, a heavy reliance on these inputs is environmentally unsustainable. Alternative approaches are necessary to maintain agricultural productivity while fostering positive environmental outcomes. The potential benefits offered by the relationship between plants and arbuscular mycorrhizal (AM) fungi is well-known, yet so much of the ecology of this association remains poorly understood, limiting its application in agriculture. Here our work shows the crucial role of AM fungal community composition in enhancing crop benefits from this symbiosis. We explore how varying factors such as nutrient availability and crop species influence these dynamics, and that a greater focus on the community assembly of AM fungi in agricultural contexts may provide new insights. https://cassyni-user-files-prod.s3.amazonaws.com/To7aDWvf3VY2WUqquheWHc https://cassyni.com/slides/outline/xTNRZArS1EReNFTMMFRBj https://cassyni.com/events/xTNRZArS1EReNFTMMFRBj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FMGbB61iTUzD3H65g9WTqp https://cassyni.com/slides/outline/U8pPsnTfhGamBDwyEPAZ4h https://cassyni.com/events/U8pPsnTfhGamBDwyEPAZ4h/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JdkPG2D2BquEykvUaJa7pA https://cassyni.com/events/U8pPsnTfhGamBDwyEPAZ4h?videoPreview=1 Old, deciduous, temperate forest under elevated CO2nohttps://cassyni.com/events/U8pPsnTfhGamBDwyEPAZ4h?videoPreview=12024-08-12T12:00:00+00:002210.4The New Phytologist FoundationThe land carbon sink is the most important carbon cycle feedback to 21st century climate change but contains many uncertainties, especially in the coupling of carbon, water, and nutrient cycling. Nutritional constraints and environmental stress may limit the land sink, especially in mature forests, which make up most of the land carbon sink. Current climate projections and Net Zero plans would then be overly optimistic. The Birmingham Institute of Forest Research (BIFoR) Free-Air CO2 Enrichment (FACE) facility is set in old UK broadleaf forest dominated by oak interspersed with sycamore, hazel, hawthorn, and holly. CO2-enrichment, which will run beyond 2026, commenced in spring 2017. The whole canopy volume of three replicate 30m-diameter plots is immersed in air containing 150 ppm extra CO2. Three neighbouring plots act as controls. The elevated-CO2 forest patches show prompt and sustained responses, the effects cascading through the ecosystem patch via carbon, water, and nutrient cycles. https://cassyni-user-files-prod.s3.amazonaws.com/JdkPG2D2BquEykvUaJa7pA https://cassyni.com/slides/outline/7Pb1w5HdG3KW3EVgxGFDBB https://cassyni.com/events/7Pb1w5HdG3KW3EVgxGFDBB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/47KkJmsvwju61meDvhQnaS https://cassyni.com/events/7Pb1w5HdG3KW3EVgxGFDBB?videoPreview=1 Liquid Rocket Engine Combustor Simulations by Flamelet-Based Model and Flux-Reconstruction Methodnohttps://cassyni.com/events/7Pb1w5HdG3KW3EVgxGFDBB?videoPreview=12024-12-05T09:00:00+00:002053.84JKW Symposium TeamLarge-eddy simulations are performed for liquid rocket engine combustors by solving the compressible Navier-Stokes equations with the flamelet progress variable model. To account for real-gas thermodynamics and transport of the cryogenic propellants, the Soave-Redlich-Kwong equation of state and Chung’s model are used. JAXA's in-house solver “LS-FLOW-HO” based on the high-order flux-reconstruction scheme is employed on overset unstructured hexahedral grids. First, a single coaxial injector case tested at JAXA Kakuda Space Center is considered. To reproduce the injector acoustic modes with proper upstream boundary conditions, the geometry of the injection manifolds is included in the simulation. The computed power spectral density (PSD) of the pressure was compared with the experimental data, and the overall characteristics agreed reasonably well. Next, LES of DLR BKD 42 injectors is conducted. The computed combustion pressure and the PSD for a higher hydrogen temperature condition agree fairly well with the experimental data. Finally, preliminary results of the LE-X full combustor simulation with over 500 injectors are presented. https://cassyni-user-files-prod.s3.amazonaws.com/47KkJmsvwju61meDvhQnaS https://cassyni.com/events/EJfUaeLyQT5HY3VGKhp9Ks/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EYBe4sMYJJzmv14JPgiDjL https://cassyni.com/slides/outline/9NBS7osj1sYG8wmvKE79bj https://cassyni.com/events/9NBS7osj1sYG8wmvKE79bj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VcbtEsidJbgfjwuKdoDE1C https://cassyni.com/events/9NBS7osj1sYG8wmvKE79bj?videoPreview=1 Conversion/Zero-derivation: 2000-2025nohttps://cassyni.com/events/9NBS7osj1sYG8wmvKE79bj?videoPreview=12025-03-05T00:10:00+00:003011.96Linguistics and Applied Language StudiesThe talk reviews the progress made in 25 years of research on morphological conversion, also known as 'zero-derivation'. It overviews generalities like the background, the concept of conversion, and the main theories, but also specific questions like the issue of directionality in conversion, the productivity, and the semanticity. The talk underlines the progress made, but it also outlines some open questions and their relevance in morphological theory.https://cassyni-user-files-prod.s3.amazonaws.com/VcbtEsidJbgfjwuKdoDE1C https://cassyni.com/slides/outline/BqRTME7MDAJkVtFUrv1nKf https://cassyni.com/events/BqRTME7MDAJkVtFUrv1nKf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LYaZoiw2ZbWunNYfywL1QJ https://cassyni.com/events/BqRTME7MDAJkVtFUrv1nKf?videoPreview=1 The Electromomentum Couplingnohttps://cassyni.com/events/BqRTME7MDAJkVtFUrv1nKf?videoPreview=12025-04-01T13:00:00+00:004477.88MetaMATWillis’ ingenious homogenization theory unveiled a macroscopic coupling between linear momentum and strain in elastic composites. By extending his theory, we discovered an analogous coupling between the linear momentum and the electric field in piezoelectric composites, which we term $electromomentum$ coupling. This coupling provides a mechanism for wave manipulation similar to Willis coupling, but with the added benefit of electrical tunability. In this talk, I will outline the methods that led to this discovery, discuss its physical origins, illustrate its role in deriving physically meaningful effective models, and demonstrate its application in wavefront shaping. This seminar is dedicated to Prof. J. R. Willis in honor of his 85th birthday.https://cassyni-user-files-prod.s3.amazonaws.com/LYaZoiw2ZbWunNYfywL1QJ https://cassyni.com/events/QBfBcwoMay5LY3Bh7qWx6R/seminar/qa https://cassyni.com/slides/outline/QBfBcwoMay5LY3Bh7qWx6R https://cassyni.com/events/QBfBcwoMay5LY3Bh7qWx6R/abstract https://cassyni-user-files-prod.s3.amazonaws.com/MCRkef7YjNWVZHpA6Gz8bx https://cassyni.com/events/QBfBcwoMay5LY3Bh7qWx6R?videoPreview=1 Variational quantum algorithms for computational fluid dynamicsnohttps://cassyni.com/events/QBfBcwoMay5LY3Bh7qWx6R?videoPreview=12025-05-20T14:00:00+00:003742.4AIAA JournalVariational quantum algorithms are particularly promising early applications of quantum computers since they are comparatively noise tolerant and aim to achieve a quantum advantage with only a few hundred qubits. They are applicable to a wide range of optimization problems arising throughout the natural sciences and industry. To demonstrate the possibilities for the aeroscience community, we describe how variational quantum algorithms can be utilized in computational fluid dynamics. We discuss how classical fluid dynamics problems are translated into quantum variational algorithms by using matrix product operators as a programming paradigm. The intricate multi-scale nature, describing the coupling between different-sized eddies in space and time, allows us to design an efficient structure-resolving tensor network based description of turbulent flows and compute their dynamics. We show how boundary conditions can be incorporated. We provide estimates for how the runtimes of the resulting quantum algorithms scale with problem size and show that only a logarithmically small number of qubits are required. We then discuss several fundamental examples demonstrating the power of these quantum algorithms. In addition, we discuss how current practical limitations in size and also imperfections of quantum hardware affect the performance of variational algorithms and determine quantum hardware requirements that might allow gaining a quantum advantage over standard classical approaches to fluid dynamics problems. Finally, we demonstrate the power of tensor network based classical algorithms for computational fluid dynamics that arise as an intermediate step in the translation to fully quantum algorithms. https://cassyni-user-files-prod.s3.amazonaws.com/MCRkef7YjNWVZHpA6Gz8bx https://cassyni.com/events/JkXY7RgakvzG9AwTWvXA6y/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7itYw9rhYiLMceGGa9Yg54 https://cassyni.com/events/KFB9A7L7CPYK8wUM7MoxNH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3H47X12ybbMUZkcFzJuwAn https://cassyni.com/events/Vcnq8Tv8R1AjfSmV8Tkr3o/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UxmXvYgGRQ8vvt3so5V9jU https://cassyni.com/events/SAFbogPTLoJ6dkTvUoNtWy/seminar/qa https://cassyni.com/slides/outline/SAFbogPTLoJ6dkTvUoNtWy https://cassyni.com/events/SAFbogPTLoJ6dkTvUoNtWy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/82MYjFHdPz4KeGRNYRqdug https://cassyni.com/events/SAFbogPTLoJ6dkTvUoNtWy?videoPreview=1 Can we discover fundamental laws from data using AI?nohttps://cassyni.com/events/SAFbogPTLoJ6dkTvUoNtWy?videoPreview=12025-04-10T12:30:00+00:002567.04MOX Laboratory - Department of MathematicsDiscovering fundamental laws governing systems from observational data has long been a hallmark of scientific inquiry. In this talk, I will discuss how recent advances in AI and machine learning enable the automated discovery of scientific laws and governing equations directly from data, revolutionizing the way we unravel system dynamics in numerous domains, including medicine and pharmacology. I will highlight how AI-driven methods uncover underlying principles, from classical physics to biological systems to medicine, and offer insights into future possibilities—transforming data-driven observations into interpretable and actionable scientific knowledge. Yet, can we push this boundary further—going beyond equations entirely? I will introduce direct semantic modeling, a novel paradigm where AI learns the behavior of dynamical systems directly from data without relying on closed-form equations. This semantic approach offers intuitive, human-interpretable insights into system evolution, marking a transformative leap in scientific discovery. (This talk is based on recent research with Krzysztof Kacprzyk, Tennison Liu and Sam Holt.)https://cassyni-user-files-prod.s3.amazonaws.com/82MYjFHdPz4KeGRNYRqdug https://cassyni.com/slides/outline/UdVd36d5Y64azgwV2VHXEu https://cassyni.com/events/UdVd36d5Y64azgwV2VHXEu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5uFL1yfxs55ggHu8Bnh5TU https://cassyni.com/events/UdVd36d5Y64azgwV2VHXEu?videoPreview=1 Gullah Geechee Sweetgrass Basket Culture and Heritage (Charleston Conference)nohttps://cassyni.com/events/UdVd36d5Y64azgwV2VHXEu?videoPreview=12024-11-13T15:00:00+00:00795.6Part of the nonprofit Annual Reviews organizationCharleston-based Andrea Cayetano-Jefferson proudly represents the rich Gullah culture through her peerless creations as a sixth generation sweetgrass basket artist. As child she studied the intricacies of basket sewing from her mother and aunt whom she attributes her commitment to continuing the traditional art form honoring her Gullah ancestors and history. As a 21st Century Gullah, Andrea is committed to keeping the legacy of her ancestors alive through education. In 2021, she was accepted into the Folklife & Traditional Arts Apprenticeship with her daughter Chelsea, and was featured in the 2020 Vandiver Gallery Exhibition at Anderson University in South Carolina. She has recently been interviewed by local and national news stations about Gullah culture and sweetgrass baskets. Andrea will share a presentation with us on the culture and heritage of Gullah Geechee sweetgrass basketmaking and its local significance here in Charleston. Her artwork will also be on display and for sale in the Gaillard lobby following her presentation. Image credit: [Leo Heisenberg (Unsplash)](https://unsplash.com/photos/cars-parked-beside-brown-concrete-building-during-daytime-A56yu_pmNKQ). Image credit: [Leo Heisenberg (Unsplash)](https://unsplash.com/photos/yellow-and-blue-concrete-building-ajxP9gEhu30).https://cassyni-user-files-prod.s3.amazonaws.com/5uFL1yfxs55ggHu8Bnh5TU https://cassyni.com/slides/outline/4Rj1mbvN2evgq1Be6hzDpZ https://cassyni.com/events/4Rj1mbvN2evgq1Be6hzDpZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/SSM1EZkvmXxQSVX2WPoLmC https://cassyni.com/events/4Rj1mbvN2evgq1Be6hzDpZ?videoPreview=1 Breaking Out of the Publishing Straightjacket: Rethinking Scholarly Outputsnohttps://cassyni.com/events/4Rj1mbvN2evgq1Be6hzDpZ?videoPreview=12025-01-14T13:00:00+00:002965.04Academic Publishing in EuropeNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/SSM1EZkvmXxQSVX2WPoLmC https://cassyni.com/events/T98UBbxDBJWM73G4LRAFdP/seminar/qa https://cassyni.com/slides/outline/T98UBbxDBJWM73G4LRAFdP https://cassyni.com/events/T98UBbxDBJWM73G4LRAFdP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QdC3xxB7iDzSor2mHbyjZQ https://cassyni.com/events/T98UBbxDBJWM73G4LRAFdP?videoPreview=1 Strengthening the OB to FM Pipeline: Rhode Island Statewide Postpartum Hypertension Remote Surveillancenohttps://cassyni.com/events/T98UBbxDBJWM73G4LRAFdP?videoPreview=12025-08-21T20:00:00+00:003252.08Family MedicineObjectives: * Review why remote self-measured blood pressure programs have become standard of care for postpartum hypertension but have significant shortcomings * Learn about how Women & Infants Hospital’s program has improved clinical outcomes * Discuss how RI-SPHERES, a statewide initiative, has potential to improve short- and long-term morbidity from hypertension via multidisciplinary partnerships https://cassyni-user-files-prod.s3.amazonaws.com/QdC3xxB7iDzSor2mHbyjZQ https://cassyni.com/events/4uxH6qqbRhatJXStMtUnff/abstract https://cassyni-user-files-prod.s3.amazonaws.com/TEZAVQwhh243NXhi4kXrhk https://cassyni.com/events/EoLhjxWPFGZ7MWUn7ow7W5/seminar/qa https://cassyni.com/slides/outline/EoLhjxWPFGZ7MWUn7ow7W5 https://cassyni.com/events/EoLhjxWPFGZ7MWUn7ow7W5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LWnDSw1mk44d2M24tbf9rv https://cassyni.com/events/HGAPFw1iQ9S2FXG2prPtVT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/SjXE6C5xXefRKb26pbrcn https://cassyni.com/events/HGAPFw1iQ9S2FXG2prPtVT?videoPreview=1 Breaking the Silence on Women's Healthnohttps://cassyni.com/events/HGAPFw1iQ9S2FXG2prPtVT?videoPreview=12026-04-30T09:00:00+00:004846.56Women's Health"Women's health research has been systematically under-studied for decades, creating profound healthcare inequities that affect diagnosis, treatment, and outcomes. Ultimately, affecting quality of life. We're finally breaking the silence on women's health through research, on conditions such as iron deficiency, which affects millions of women daily. This isn't just about filling research gaps—it's about dismantling gender biases in healthcare and transforming how we approach women's health from the workplace to the clinic. The data is telling a story we can no longer ignore, and the solutions are within reach." - Dr Cory Dugan, Co-Guest Editor of the Special Collectionhttps://cassyni-user-files-prod.s3.amazonaws.com/SjXE6C5xXefRKb26pbrcn https://cassyni.com/events/Y5cWeSRTZt3NW8yQLtsFMX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NjZr6efxLA5C72W3kFRiZU https://cassyni.com/events/CKgLo6YU1Ztio6yMKmLX5f/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KcEPQJ212cdmkXwnCU8AJ https://cassyni.com/slides/outline/2SiFsRbyEQpPwayKpCa9wj https://cassyni.com/events/2SiFsRbyEQpPwayKpCa9wj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/MAKud1tafQdb5n62DxUeC6 https://cassyni.com/events/2SiFsRbyEQpPwayKpCa9wj?videoPreview=1 Looking back over a career in bioengineeringnohttps://cassyni.com/events/2SiFsRbyEQpPwayKpCa9wj?videoPreview=12025-07-08T04:00:00+00:004391.48The Auckland Bioengineering InstituteThis talk will describe some key moments in my career and try to draw some lessons, especially in team building and remaining inquisitive … but including the ups and downs. https://cassyni-user-files-prod.s3.amazonaws.com/MAKud1tafQdb5n62DxUeC6 https://cassyni.com/slides/outline/FnDa7t595mmMpoGuyRiUcV https://cassyni.com/events/FnDa7t595mmMpoGuyRiUcV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CsdHd8R77x8CJEaGyanZkA https://cassyni.com/events/FnDa7t595mmMpoGuyRiUcV?videoPreview=1 An Update to the Transparency and Openness Promotion Guidelinesnohttps://cassyni.com/events/FnDa7t595mmMpoGuyRiUcV?videoPreview=12025-06-16T19:00:00+00:003633.84Published in 2015, the Transparency and Openness Promotion Guidelines (TOP 2015) provided a framework for journals to design and implement publication standards aligned with these values. Since its publication, stakeholders have used TOP 2015 across various disciplines, research paradigms, study designs, and thousands of journals and other organizations (e.g., preprint platforms, publishers, funders, and research institutions). The TOP Guidelines Advisory Board decided to update TOP 2015 in order to incorporate insights from those who have used TOP and from the meta-scientific literature over the past decade. This moderated panel will discuss TOP 2025: this first major update to the TOP Guidelines. TOP 2025 includes a conceptual framework to clarify its primary objective—promoting the verifiability of empirical research claims—and to guide the reorganization, revisions, and recommended applications of the TOP Guidelines for use across its broad range of stakeholders. TOP 2025 makes three major classes of updates. First, standards are reconfigured into three distinct types: research practices, verification practices, and verification studies. Second, for research practices, levels are now streamlined so that they follow the same logical structure for all practices: disclosure (Level 1), share and cite (Level 2), and certify (Level 3). Third, we have revised the registration and reporting research practices based on cross-disciplinary feedback. TOP 2025 will help journals improve the verifiability of empirical research claims in articles they publish, and provide a shared framework for other organizations across the global research enterprise to coordinate efforts that promote transparency and openness.https://cassyni-user-files-prod.s3.amazonaws.com/CsdHd8R77x8CJEaGyanZkA https://cassyni.com/events/3S365RQuWgrGkpVjCjyvPF/seminar/qa https://cassyni.com/slides/outline/3S365RQuWgrGkpVjCjyvPF https://cassyni.com/events/3S365RQuWgrGkpVjCjyvPF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GHna8Rz324mtbYZfSgFZsC https://cassyni.com/events/3S365RQuWgrGkpVjCjyvPF?videoPreview=1 EP4: Machine Learning on Structuresnohttps://cassyni.com/events/3S365RQuWgrGkpVjCjyvPF?videoPreview=12025-07-17T11:00:00+00:006459.6Institute of Natural SciencesChaired by Prof. Shi JIN, this 4th webinar invites Prof. Yu Guang WANG and Prof. Zheng MA to present their latest research about Machine Learning on Structures.https://cassyni-user-files-prod.s3.amazonaws.com/GHna8Rz324mtbYZfSgFZsC https://cassyni.com/events/NhKet5eNdYSsU5xtdSDrPo/seminar/qa https://cassyni.com/slides/outline/NhKet5eNdYSsU5xtdSDrPo https://cassyni.com/events/NhKet5eNdYSsU5xtdSDrPo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8GfvzHYJyRcRfFwLNTB9wt https://cassyni.com/events/NhKet5eNdYSsU5xtdSDrPo?videoPreview=1 Algorithms and Optimisationnohttps://cassyni.com/events/NhKet5eNdYSsU5xtdSDrPo?videoPreview=12025-06-25T14:30:00+00:005352.84Nektar++ Development TeamThe Helmholtz and Poisson equations are key components of the splitting scheme to solve the incompressible Navier-Stokes equations. This talk will be dedicated to the performance and convergence tuning of a Helmholtz solver that is based on the discontinuous Galerkin discretisation and interior penalty method. First, a cache-friendly, AVX-enabled matrix-free discontinuous Galerkin operator is implemented, which not only supports a variety of spectral elements and variable polynomial orders but also achieves a throughput of $10^8$ to $10^9$ DOFs per second on a single CPU node. Then, a p-multigrid preconditioner is constructed to accelerate the convergence of high-order large problems. The multigrid preconditioner is also matrix-free except for the AMG solver on the linear mesh. The multigrid configuration is carefully tuned to reduce to overall runtime, which varies for different spectral elements. https://cassyni-user-files-prod.s3.amazonaws.com/8GfvzHYJyRcRfFwLNTB9wt https://cassyni.com/events/PByFvmHu4zzvTrVnDsWef7/seminar/qa https://cassyni.com/slides/outline/PByFvmHu4zzvTrVnDsWef7 https://cassyni.com/events/PByFvmHu4zzvTrVnDsWef7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PDz1m4JV2bWzUNfH67dtwQ https://cassyni.com/slides/outline/Doen3mzvjJUhHKnsDqvp4m https://cassyni.com/events/Doen3mzvjJUhHKnsDqvp4m/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PAtya3dqA8yyjTW5zbfLN2 https://cassyni.com/events/Doen3mzvjJUhHKnsDqvp4m?videoPreview=1 Accelerating Aotearoa’s Net Zero Emissions Targetnohttps://cassyni.com/events/Doen3mzvjJUhHKnsDqvp4m?videoPreview=12023-05-16T23:00:00+00:001357.8Business SchoolThe pursuit of Aotearoa New Zealand's net-zero emissions target faces significant challenges, with research indicating that approximately one-third of businesses globally are likely to miss 2050 targets. New Zealand is identified as lagging in the integration of technology and sustainability, particularly due to a lack of governance in enterprises. Emission reduction efforts must address Scope 1 (direct enterprise emissions), Scope 2 (utility and energy sector emissions), and the more complex Scope 3 (supply chain emissions). Three technologies are instrumental in accelerating progress: cloud computing, data analytics, and the Internet of Things (IoT), defined as interconnected devices that collect and transmit data. Experimental applications demonstrate their impact. An IoT microscope, for example, reduces parasite detection time in livestock from days to seconds, enabling precise, on-site treatment. This approach not only reduces antibiotic resistance but also decreases methane and CO2 emissions from animals by up to 30%, targeting the 20% of the herd that carries over 80% of parasites. In wastewater treatment, IoT devices measure operational (Scope 1 and 2) emissions, specifically potent nitrous oxide (N2O), which is 200 times more impactful than CO2. Monitoring and model training facilitate plant control to shift emissions from N2O to CO2. Addressing broader ecosystem problems necessitates collaborative data-driven approaches. The Mahurangi Harbour M1 data collaborative, for instance, focuses on environmental and supply chain data to mitigate the impacts of urbanization runoff and climate change on oyster farming. Effective emissions management relies on the ability to measure, make data-informed decisions, and take precise action. A transition from qualitative to quantitative reporting is critical, coupled with the development of industry-specific rather than generic technological solutions. Collaborative governance of data across systems, often facilitated by digital twins, is essential for purposeful and impactful interventions in climate change adaptation and carbon emission reduction.https://cassyni-user-files-prod.s3.amazonaws.com/PAtya3dqA8yyjTW5zbfLN2 https://cassyni.com/slides/outline/CpMZxQhsrPNYcZxs7sTVFs https://cassyni.com/events/CpMZxQhsrPNYcZxs7sTVFs/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2a4PvD3fZ9dv3Mba71MWsQ https://cassyni.com/events/CpMZxQhsrPNYcZxs7sTVFs?videoPreview=1 The Future of Mobility - toward an Open Mobility Ecosystemnohttps://cassyni.com/events/CpMZxQhsrPNYcZxs7sTVFs?videoPreview=12020-09-01T23:00:00+00:003986.84Business SchoolThe proliferation of private vehicles and escalating urban congestion necessitates a re-evaluation of current mobility paradigms. This analysis explores transformative forces shaping the future of urban transport, focusing on micro-mobility, autonomous and electric vehicles (AEVs), and digital infrastructure. Micro-mobility, particularly e-bikes, is identified as a rapidly growing sector capable of replacing up to half of private car trips, offering a cost-effective and efficient solution for short-to-medium distances. While AEVs promise decarbonization and enhanced safety, unmanaged integration risks exacerbating congestion and revenue loss. Achieving a "heaven scenario" of significantly reduced vehicle numbers (e.g., 90%) relies on widespread adoption of shared AEVs, with their full impact expected by 2030. To navigate these shifts, an "Open Mobility Ecosystem" is proposed as an alternative to fragmented or monopolistic digital systems. This ecosystem leverages open-source technology, including a "mobility hub" for aggregating transport inventory and a "white-label app" for multi-modal journey planning. Blockchain-enabled self-sovereign identity is presented as a crucial component for ensuring individual privacy while enabling necessary verifications within the network. This framework allows cities to access anonymized mobility data for informed policy-making, incentivizes sustainable behaviours, facilitates dynamic pricing based on factors like occupancy, and supports demand offloading between service providers. The proposed approach aims to manage urban mobility through smart pricing and prioritization, fostering an equitable and efficient transport system without abolishing private vehicle ownership.https://cassyni-user-files-prod.s3.amazonaws.com/2a4PvD3fZ9dv3Mba71MWsQ https://cassyni.com/slides/outline/PgeV65TJupUkHKVJ1ydcqK https://cassyni.com/events/PgeV65TJupUkHKVJ1ydcqK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EHRw7MeuXyhUbGsubpy8jp https://cassyni.com/events/PgeV65TJupUkHKVJ1ydcqK?videoPreview=1 Mechanism-based mechanical metamaterialsnohttps://cassyni.com/events/PgeV65TJupUkHKVJ1ydcqK?videoPreview=12025-06-16T07:00:00+00:003462.68ETOPIMThe design and analysis of mechanism-based mechanical metamaterials is a relatively new and rapidly growing research area. It studies artificial “materials” that take advantage of “mechanisms” (that is, nontrivial energy-free deformations) to achieve interesting macroscopic behavior. The relevant mechanics is nonlinear, since mechanisms involve large rotations. While there have been insightful studies of specific examples, many questions remain poorly understood. I will focus on the existence and characterization of soft modes. Roughly speaking, soft modes are macroscopic deformations that are not mechanisms, but that nevertheless require very little elastic energy. In simple examples (such as the “rotating squares metamaterial”) they are achieved by modulating a mechanism. However there are systems (such as the “Kagome metamaterial”) with many mechanisms. For such systems a different approach is needed. I will present a homogenization-based perspective developed in recent work with Xuenan Li. Using this approach, I’ll explain in particular why the only soft modes of the Kagome metamaterial are compressive conformal maps. The Kagome example is interesting because it has a huge amount of microstructural freedom, yet its macroscopic behavior is well-defined and fits into the framework of nonlinear elasticity.https://cassyni-user-files-prod.s3.amazonaws.com/EHRw7MeuXyhUbGsubpy8jp https://cassyni.com/slides/outline/LE7FmHvdqcc7FdBjNKFfJV https://cassyni.com/events/LE7FmHvdqcc7FdBjNKFfJV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WpsftFuGpoKvekY4iG6dNv https://cassyni.com/events/LE7FmHvdqcc7FdBjNKFfJV?videoPreview=1 Spatiospectral shaping of pulse propagation through diffusive medianohttps://cassyni.com/events/LE7FmHvdqcc7FdBjNKFfJV?videoPreview=12025-06-17T05:00:00+00:002110.72ETOPIMThe transmission of short pulses through random media is impeded by multiple-scattering, which distorts the pulse's spatiotemporal profile and reduces the peak transmitted power. We have achieved unprecedented control of pulse propagation through a diffusive system by exploring both spatial and spectral degrees of freedom. With spatiospectral shaping of an incident pulse, its diffusion is stopped temporally and then quickly transitions to ballistic-like transport for enhancement of peak transmitted power. Our approach is based on the spatiospectral transmission matrix, which is constructed from frequency-resolved transmission matrices. We obtain a 35-fold enhancement in peak power of transmitted pulse, by controlling 971 spatial and spectral degrees of freedom in a two-dimensional diffusive waveguide. We illustrate the power of spatiospectral shaping by comparing it to spatial-only, spectral-only, sequential spatial and spectral control. Supported by analytic theory and numerical simulations, our results establish the physical limits of manipulating pulse propagation in diffusive media. https://cassyni-user-files-prod.s3.amazonaws.com/WpsftFuGpoKvekY4iG6dNv https://cassyni.com/events/WbiwjeWf4EEXn8UsPRCYz1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3QtdpKVeTtc8SAZZ87PZug https://cassyni.com/events/WbiwjeWf4EEXn8UsPRCYz1?videoPreview=1 Topology-inspired routes to optical field confinement and enhancement in 2-dimensional photonic crystalsnohttps://cassyni.com/events/WbiwjeWf4EEXn8UsPRCYz1?videoPreview=12025-06-18T03:00:00+00:001845.72ETOPIMWe explore the use of topological channels and symmetry breaking in two-dimensional silicon photonic crystals to establish new paradigms for the confinement and enhancement of light fields at the nanoscale. This includes highly degenerate Landau level flat bands in strained photonic crystals, as well as broadband localization of light due to suppressed backscattering in terminated topological waveguides.https://cassyni-user-files-prod.s3.amazonaws.com/3QtdpKVeTtc8SAZZ87PZug https://cassyni.com/slides/outline/X6NYnLABVgnamu1kyrVMFK https://cassyni.com/events/X6NYnLABVgnamu1kyrVMFK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/S2FbB1WFy8bRn4NDhRkj5Q https://cassyni.com/events/X6NYnLABVgnamu1kyrVMFK?videoPreview=1 Spatio-temporal metamaterials for lightnohttps://cassyni.com/events/X6NYnLABVgnamu1kyrVMFK?videoPreview=12025-06-19T23:00:00+00:001958.16ETOPIMMetamaterials have revolutionised the way we control light transport and generation. Yet, to date, they rely on static and passive architectures, only redistributing incident wave energy -for example a metalens that focuses light or a cloak that makes an object invisible. The next frontier is to control metamaterials in space and time and make waves from the past and future to interact. I will discuss our first steps towards temporal control and experiments on double-slit time diffraction at optical frequencies in time-varying metamaterials [1] and how we can extend the modulation of the linear refractive index to the modulation of the nonlinear response [2]. Intertwining space and time, I will discuss the observation of the temporal version of coherent perfect absorption [3] and scattering of light from optical modulations traveling faster than the speed of light [4] and how this will enable us to simulate more complex phenomena. https://cassyni-user-files-prod.s3.amazonaws.com/S2FbB1WFy8bRn4NDhRkj5Q https://cassyni.com/slides/outline/RfEuGp3QfehWP2mXNwVZFs https://cassyni.com/events/RfEuGp3QfehWP2mXNwVZFs/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Av6FySR6tSnsrD1Ei2Boan https://cassyni.com/events/RfEuGp3QfehWP2mXNwVZFs?videoPreview=1 Scattering singularities of a resonant cavity containing plasmanohttps://cassyni.com/events/RfEuGp3QfehWP2mXNwVZFs?videoPreview=12025-06-19T23:00:00+00:00600.16ETOPIMThe interaction between plasma and electromagnetic resonant cavities is critical for applications ranging from plasma reactors in surface processing to electric propulsion systems requiring vacuum chambers. This study investigates how plasma influences the scattering singularities—specifically poles and zeros—of a resonant cavity, which fundamentally affect its resonant and scattering properties. The approach combines experimental measurements of the reflection coefficient using a Vector Network Analyser with a numerical model based on the Drude description of plasma permittivity, incorporating electron density, gas pressure, and wave frequency. The model is validated by close agreement with experimental data both without and with plasma, capturing amplitude and phase responses across the frequency band. Analysis focuses on the second resonance mode, examining how varying gas pressure at fixed electron density shifts the scattering singularities in the complex frequency plane: the real part of the frequency shifts upward while the imaginary part decreases. This behavior is explained by electron dynamics within the plasma, where increasing pressure leads to more frequent electron-neutral collisions, modulating energy transfer and internal decay rates. The results demonstrate that plasma parameters can be used to control scattering singularities, thereby tuning the resonator’s electromagnetic response. Future work aims to extend the analysis across different electron densities to further elucidate plasma’s role in resonant cavity behavior.https://cassyni-user-files-prod.s3.amazonaws.com/Av6FySR6tSnsrD1Ei2Boan https://cassyni.com/events/8sCMha3Zk5s7yPCb1KotHb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FUsGvo3istttRBUMsNPx2i https://cassyni.com/slides/outline/TUJ1KLhADZcDM1gTACFqX https://cassyni.com/events/TUJ1KLhADZcDM1gTACFqX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AAymJZFboMKAqwJ5Xf46Si https://cassyni.com/events/TUJ1KLhADZcDM1gTACFqX?videoPreview=1 3Rs principles put into practice: animals and alternativesnohttps://cassyni.com/events/TUJ1KLhADZcDM1gTACFqX?videoPreview=12025-09-08T11:00:00+00:004770.0The Pharmacological Research family of journalsJoin us for an insightful two-part webinar, featuring expert perspectives on advancing ethical and scientific standards in animal research. In Part 1 - “**Animal Models, 3R Principles, and Alternative In Vitro Models**,” **Giuliano Grignaschi**, Head of the Animal Welfare Office at the University of Milan, will explore the implementation of the 3Rs—Replacement, Reduction, and Refinement—in compliance with European Directive 63/2010. He will discuss the ongoing necessity of using live animals in certain scientific procedures while emphasizing the importance of systematically applying the 3Rs throughout the entire research process. This session will highlight strategies to ensure high standards of animal welfare, including prioritizing alternative methods such as invertebrates and non-animal techniques whenever feasible. In Part 2 - "**How Can We Best Design Pharmacological Experiments to Produce Reliable Data While Complying with the 3Rs**” - **Fabrizio Gardoni**, Professor of Pharmacology at the University of Milan, will address the challenges of designing robust pharmacological experiments that align with the 3Rs principles. His presentation will cover best practices for optimizing experimental design through power analysis, employing innovative alternatives like in vitro models and organ-on-chip systems, and enhancing reproducibility via standardized protocols and open data sharing. Additionally, he will discuss refinement approaches that minimize animal suffering and the integration of cutting-edge technologies—including artificial intelligence and machine learning—to improve data reliability while upholding ethical responsibility. Together, these complementary presentations provide a comprehensive overview of how the 3Rs can be effectively incorporated into scientific research, balancing the pursuit of knowledge with the highest standards of animal welfare. Don’t miss this opportunity to deepen your understanding of ethical research practices and innovative alternatives in the life scienceshttps://cassyni-user-files-prod.s3.amazonaws.com/AAymJZFboMKAqwJ5Xf46Si https://cassyni.com/events/4ttckvFv7zPGhxJsobwLrh/seminar/qa https://cassyni.com/slides/outline/4ttckvFv7zPGhxJsobwLrh https://cassyni.com/events/4ttckvFv7zPGhxJsobwLrh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/S8bewim3yB45kLbLFHdLfx https://cassyni.com/events/4ttckvFv7zPGhxJsobwLrh?videoPreview=1 Higher Education librarians and social class backgroundnohttps://cassyni.com/events/4ttckvFv7zPGhxJsobwLrh?videoPreview=12025-10-31T15:00:00+00:003155.08Library & Information ServicesSocial class remains a significant barrier to social mobility in the UK, despite the strides in widening participation in higher education (HE). Research from the Social Mobility Commission (2023) showed enduring challenges in social mobility, with children of working-class parents significantly less likely to gain employment in professional occupations or gain HE qualifications compared to peers from middle or upper class backgrounds. Participation in postgraduate education (typically a prerequisite for employment as an academic librarian) were markedly lower amongst young people from working-class backgrounds, especially at more selective institutions (149-151). In reference to libraries, the latest information workforce survey from CILIP/ARA (2023) identified socio-economic background as a key barrier to professional entry. This seminar will share and discuss interim findings from a mixed-methods PhD study exploring social class and higher education librarians' professional identity, workplace experiences and practices. First, Darren will outline the theoretical framework of the study and describe how Bourdieusian class analysis was integrated into a librarian workplace study. Next, the mixed-methods structure and approach will be described, with particular reference to the use of latent class analysis in the quantitative stage, and 'River of Life' method used to generate narrative data in the qualitative stage. Findings from the quantitative stage will be shared alongside interim findings from the qualitative stage. Throughout opportunities will be provided for attendees to discuss and ask questions about the study, its methods and findings. https://cassyni-user-files-prod.s3.amazonaws.com/S8bewim3yB45kLbLFHdLfx https://cassyni.com/events/Fm9umxVTn4ZkEE8uR9B2oX/seminar/qa https://cassyni.com/slides/outline/Fm9umxVTn4ZkEE8uR9B2oX https://cassyni.com/events/Fm9umxVTn4ZkEE8uR9B2oX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7jRC5S2QpM4Te2F2zDaLAa https://cassyni.com/events/R9W1maJKX824xze12Yq9Gh/seminar/qa https://cassyni.com/slides/outline/R9W1maJKX824xze12Yq9Gh https://cassyni.com/events/R9W1maJKX824xze12Yq9Gh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XkVwgRtaTxL5q9G6YTEYoG https://cassyni.com/events/R9W1maJKX824xze12Yq9Gh?videoPreview=1 Chimpanzees and children are curious about social interactionsnohttps://cassyni.com/events/R9W1maJKX824xze12Yq9Gh?videoPreview=12025-10-14T16:00:00+00:003854.44Royal Society PublishingCuriosity is adaptive, enhances learning, and reduces uncertainty. Social curiosity is defined as the motivation to gain information about the actions, relationships, and psychology of others. Little is known about the developmental and evolutionary roots of social curiosity. Here, across three comparative studies, we investigate whether chimpanzees (n = 27) and young children (4–6 years old, n = 94) show particular interest in social interactions among third parties. Chimpanzees and children preferred to watch videos of social interactions compared with videos of a single conspecific (Experiment 1) and young children and male chimpanzees even paid a material cost to gain social information (Experiment 2). Finally, our results show that boys become more curious about negative social interactions whereas girls become more curious about positive social interactions as they develop, while chimpanzees demonstrated no preference for negative versus positive social interactions (Experiment 3). Taken together, these findings suggest that social curiosity emerges early in human ontogeny and is shared with one of our two closest living relatives, the chimpanzees. Image: [Alpha male chimpanzee at Kibale forest National Park, Giles Laurent. 2022](https://commons.wikimedia.org/wiki/File:013_Alpha_male_chimpanzee_at_Kibale_forest_National_Park_Photo_by_Giles_Laurent.jpg)https://cassyni-user-files-prod.s3.amazonaws.com/XkVwgRtaTxL5q9G6YTEYoG https://cassyni.com/events/MCLoWje1QpWeL7TZsqnsXb/seminar/qa https://cassyni.com/slides/outline/MCLoWje1QpWeL7TZsqnsXb https://cassyni.com/events/MCLoWje1QpWeL7TZsqnsXb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HngWwx7v9rww9mvUX2GR98 https://cassyni.com/events/MCLoWje1QpWeL7TZsqnsXb?videoPreview=1 Rheotaxis: Invasion of bacteria swimming upstream into microstructured devicesnohttps://cassyni.com/events/MCLoWje1QpWeL7TZsqnsXb?videoPreview=12025-09-18T14:00:00+00:005948.28Journal of Biological PhysicsBacteria have the remarkable ability to swim upstream, a process called rheotaxis. This motion against flows can cause not only respiratory, gastrointestinal, and urinary tract infections, but also the contamination of medical devices and hospital equipment. However, it remains unknown how bacteria navigate upstream through these microstructured environments with narrow channels and wide cavities. Here, combining microbiology experiments with nanofabrication and mathematical modeling, we reveal how Escherichia coli bacteria invade in four stages: The (I) break-out from colonized cavities against the current, (II) propagation upstream in narrow connectors, (III) infiltration of new cavities, and (IV) colonization with biofilms under flow. Surprisingly, we find that wider channels with faster counterflows are actually more prone to invasion, but these incursions can be inhibited effectively with sharp corner designs. Next, we explore the serial invasion of multiple cavities in a row. We discover that instead of colonizing these nodes one by one slowly, the bacteria rapidly swim all the way upstream and form biofilm streamers there to take possession of the entire channel three times faster. These results shed new light on pathogen motility in host-relevant shear regimes, and they offer solutions that can be implemented directly in biomedical devices.https://cassyni-user-files-prod.s3.amazonaws.com/HngWwx7v9rww9mvUX2GR98 https://cassyni.com/events/X5JtSQaWByayBdTbPQZEfX/seminar/qa https://cassyni.com/slides/outline/X5JtSQaWByayBdTbPQZEfX https://cassyni.com/events/X5JtSQaWByayBdTbPQZEfX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/84wiM2sxG5CN1BVAZKFDQi https://cassyni.com/events/X5JtSQaWByayBdTbPQZEfX?videoPreview=1 Trends in Image Aesthetics Assessmentnohttps://cassyni.com/events/X5JtSQaWByayBdTbPQZEfX?videoPreview=12025-10-09T12:00:00+00:003297.04Journal on Image and Video ProcessingWith the popularity of powerful imaging sensors, it has been easy to obtain high-technical-quality images. Accordingly, people are increasingly concerned about the aesthetic perception of digital images. Image aesthetics assessment (IAA) has become a hot topic in both academia and industry, which has extensive applications in digital photography, album curation and image editing, etc. In this talk, we discuss the latest advances on this interesting topic, including but not limited to generic aesthetic quality evaluation, personalized aesthetics, and image cropping. https://cassyni-user-files-prod.s3.amazonaws.com/84wiM2sxG5CN1BVAZKFDQi https://cassyni.com/events/ReBEvtTjMwVtnmDMnVZSg5/seminar/qa https://cassyni.com/slides/outline/ReBEvtTjMwVtnmDMnVZSg5 https://cassyni.com/events/ReBEvtTjMwVtnmDMnVZSg5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4azG5FcdvHjBgRSAHRm4Tp https://cassyni.com/events/ReBEvtTjMwVtnmDMnVZSg5?videoPreview=1 Engineered Acoustic Structures - From Enhanced Consumer Audio to Clean Energynohttps://cassyni.com/events/ReBEvtTjMwVtnmDMnVZSg5?videoPreview=12025-11-25T14:00:00+00:003946.04MetaMATControlling acoustic waves is critical in many fields, including verbal communication, medical imaging, structural health monitoring, ocean exploration, and national security. Engineered acoustic structures, also known as acoustic metamaterials, are artificially designed structures that can control the behavior of sound waves by manipulating the effective material properties of the structure. In recent years, these structures have been proposed as a promising approach to wave control, but their power efficiency and frequency range have often been limiting factors for consumer audio applications. In this talk, I will present a series of my works on how to achieve 100% power efficiency in arbitrary wavefront control using engineered acoustic structures. When combined with optimization, I will show our recent success in efficiently controlling the acoustic radiation within an ultra-broad bandwidth from 1kHz to 10kHz. In addition to providing reliable and affordable solutions to audio applications, we have also extended the use of engineered structures to reduce noise in water environments, with the aim to reduce the piling noise during offshore windfarm construction.https://cassyni-user-files-prod.s3.amazonaws.com/4azG5FcdvHjBgRSAHRm4Tp https://cassyni.com/slides/outline/6Ntg8EEGF5u22BArsBy8ys https://cassyni.com/events/6Ntg8EEGF5u22BArsBy8ys/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7G2jtrhf55bxH1Tgb1wXTL https://cassyni.com/events/6Ntg8EEGF5u22BArsBy8ys?videoPreview=1 Behind bars: The invention of mass incarcerationnohttps://cassyni.com/events/6Ntg8EEGF5u22BArsBy8ys?videoPreview=12022-03-23T06:00:00+00:003836.92Part of the nonprofit Annual Reviews organizationPrisons were once considered a sign of progress, a victory for public health that was more humane than disease-ridden, overcrowded jails and the harsh physical punishments meted out on the town green. Yet today, prisons face a legitimacy crisis, and are considered by many policymakers and reformers as bloated, inhumane institutions. Even as scholarly work suggests that they are ineffective at making us safer, society has come to take the need for prisons and mass incarceration for granted. How did we get here? How have our attitudes toward prison, which some scholars date to around the time of the American Revolution, changed over time? Are prisons intended to punish, to rehabilitate, or both? What’s reasonable to ask of prisons and do they ever work as intended? How is incarceration experienced by those who are imprisoned?https://cassyni-user-files-prod.s3.amazonaws.com/7G2jtrhf55bxH1Tgb1wXTL https://cassyni.com/slides/outline/EJMdKigDyUtHvVF1Dcsx9s https://cassyni.com/events/EJMdKigDyUtHvVF1Dcsx9s/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8Yp8tzvqGPePCHSfynFUpn https://cassyni.com/events/EJMdKigDyUtHvVF1Dcsx9s?videoPreview=1 AI in science: Accelerating discovery?nohttps://cassyni.com/events/EJMdKigDyUtHvVF1Dcsx9s?videoPreview=12025-07-01T08:00:00+00:005378.32This seminar explores the multifaceted role of artificial intelligence (AI) in accelerating scientific discovery, emphasizing both its transformative potential and inherent challenges. Key applications include AI-driven improvements in complex system modeling, exemplified by enhanced hurricane trajectory predictions and the breakthrough AlphaFold model for protein structure prediction, which has provided over 200 million structures to researchers worldwide and facilitated advances in drug safety and antimicrobial resistance research. The integration of AI in scientific workflows is shown to address data scale and complexity, automate hypothesis generation, and support decision-making. However, equitable access remains a critical concern, particularly for researchers in low- and middle-income countries, where limited resources and infrastructure constrain AI adoption. Philosophical and ethical considerations highlight risks such as reduced creativity, opacity of AI models, potential entrenchment of biases, and the undervaluation of routine scientific tasks that may harbor discovery potential. The necessity for transparent evaluation, multidisciplinary collaboration, and responsible innovation is underscored. Additionally, the seminar presents data-driven approaches to maximize research impact through AI-enabled analysis of publication, patent, and funding data, revealing hidden innovation potential within institutions and enabling predictive modeling of translational outcomes. These insights advocate for human–machine partnerships to enhance research efficiency and societal benefit. The discussion concludes by posing critical questions on identifying major scientific challenges suitable for AI intervention, ensuring responsible use, and fostering inclusive metascience to understand AI’s evolving influence on scientific practice.https://cassyni-user-files-prod.s3.amazonaws.com/8Yp8tzvqGPePCHSfynFUpn https://cassyni.com/events/GFrm3uAm2EyLshAtNkjW7o/seminar/qa https://cassyni.com/slides/outline/GFrm3uAm2EyLshAtNkjW7o https://cassyni.com/events/GFrm3uAm2EyLshAtNkjW7o/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UdgbnyYTJUa6hJc336d17L https://cassyni.com/events/GFrm3uAm2EyLshAtNkjW7o?videoPreview=1 Decolonising and Diversifying the Humanities and Social Sciences: Lessons from the New Palgrave Dictionary of Economicsnohttps://cassyni.com/events/GFrm3uAm2EyLshAtNkjW7o?videoPreview=12025-11-19T15:00:00+00:004565.32Palgrave MacmillanIn this year’s Palgrave Lecture, Matías Vernengo, one of the Editors-in-Chief of the forthcoming fourth edition The New Palgrave Dictionary of Economics, discusses the process of decolonialising and diversifying the leading reference work in economics. For a discipline that studies choices made by, and affecting, everyone on the planet, it is peculiar that economics has been so restrictive in terms of what is studied and who is listened to. Of the 96 recipients of the Nobel Prize in Economics, just three are women and over 90% come from North America and Western Europe. So, how does one tackle the task of revising a work like The New Palgrave Dictionary of Economics, when all previous editions have reflected the limitations of the economics profession, particularly its Eurocentric and gender-biased character? Matías will talk about how he and his colleagues Esteban Pérez Caldenteya and Jayati Ghosh are directly addressing these issues by focusing on the economic history, institutions, and unique challenges of the Global South. He discusses how their work aims to expand the list of influential thinkers by including scholars from the Global South and other marginalized groups, while also exploring neglected topics like unpaid labor, subsistence farming, informal economies, and the economic impacts of climate change on vulnerable populations. He argues that this expanded focus does not necessarily require an entirely new theoretical framework for the periphery, as a form of universalism remains possible by incorporating the distinct historical context of developing countries. Image credit: [Sean Sinclair (Unsplash)](https://unsplash.com/photos/a-blurry-image-of-a-rainbow-colored-background-C_NJKfnTR5A).https://cassyni-user-files-prod.s3.amazonaws.com/UdgbnyYTJUa6hJc336d17L https://cassyni.com/slides/outline/DHutYYFqamoFsHfLsTGQ5b https://cassyni.com/events/DHutYYFqamoFsHfLsTGQ5b/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GyKFYvDcvSkbSVhakit9Hx https://cassyni.com/events/DHutYYFqamoFsHfLsTGQ5b?videoPreview=1 Localized Roadmaps to Fight the Climate Crisisnohttps://cassyni.com/events/DHutYYFqamoFsHfLsTGQ5b?videoPreview=12022-04-30T08:00:00+00:00933.68 School of Public PolicyAvoiding costly climate change necessitates actions at every political scale and across all sectors of the economy. The climate countdown has begun, but progress is slow. One reason is that we lack localized roadmaps that provide people at all scales of society a set of solutions that they can enthusiastically support. The research underpinning the “Drawdown Georgia” project illustrates how robust place-specific plans for climate action can be derived from foundational global and national work. Its replicable methodology advances the science of carbon abatement by incorporating solution interdependencies, by spanning both carbon sources and sinks, and by emphasizing beyond-carbon societal costs and benefits. By focusing on the 2030 timeframe, Drawdown Georgia highlights pathways for immediate action that can help put jurisdictions and states on a road toward net-zero emissions by mid-century. While the specifics of this research are unique to Georgia, our approach is generalizable. It can easily be replicated around the world, because solutions happen locally and they scale in real life against the backdrop of day-to-day issues that matter to people and communities. Elected in 2020, Brown represents the Academy's section on Human Environmental Sciences.https://cassyni-user-files-prod.s3.amazonaws.com/GyKFYvDcvSkbSVhakit9Hx https://cassyni.com/slides/outline/NgFzYA4hKqFFsWpt59gQaq https://cassyni.com/events/NgFzYA4hKqFFsWpt59gQaq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BiyydhtA9aDQSdA82EM9xz https://cassyni.com/events/NgFzYA4hKqFFsWpt59gQaq?videoPreview=1 How to Get Started with Faculty Development on Artificial Intelligencenohttps://cassyni.com/events/NgFzYA4hKqFFsWpt59gQaq?videoPreview=12025-05-22T08:00:00+00:003642.28AAMCSpeakers share strategies for designing and delivering impactful AI training in medical education for faculty development. This webinar is part of the Artificial Intelligence in Academic Medicine Webinar Series, hosted by the AAMC. It explores critical concepts, the current landscape, and practical strategies drawn from various perspectives and institutions to support you in navigating the evolving world of AI in academic medicine. For more information, see [the complete series webpage](https://www.aamc.org/about-us/mission-areas/medical-education/artificial-intelligence-ai-academic-medicine-webinar-series). https://cassyni-user-files-prod.s3.amazonaws.com/BiyydhtA9aDQSdA82EM9xz https://cassyni.com/slides/outline/PAubaqiDmHoJsHMmfayCr9 https://cassyni.com/events/PAubaqiDmHoJsHMmfayCr9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/YH5pdNQfMY6QGGhVAk9JHC https://cassyni.com/events/PAubaqiDmHoJsHMmfayCr9?videoPreview=1 Debate: Should The U.S. Ban TikTok? Kori Schake and Milton Muellernohttps://cassyni.com/events/PAubaqiDmHoJsHMmfayCr9?videoPreview=12023-03-03T09:00:00+00:003036.08 School of Public PolicyThe debate on whether the United States should ban TikTok centers on concerns about national security risks posed by the Chinese-owned social media platform, which has approximately 94 million U.S. users. One perspective emphasizes two primary threats: the extensive data collection by TikTok, potentially accessible to the Chinese government under China’s extraterritorial data laws, and the platform’s capacity for censorship and propaganda manipulation, as evidenced during the Hong Kong protests and Uyghur detentions. This view highlights bipartisan political concern and actions restricting TikTok on government devices, arguing that the risks of espionage and media influence outweigh the benefits of the app’s popularity. Conversely, the opposing argument challenges the evidence for these threats, noting the absence of Chinese censorship on TikTok’s global app and emphasizing the company’s commercial motivations and operational independence. It contends that data accessible through TikTok is largely public or obtainable via other social media platforms, and that banning TikTok risks undermining American values of openness, free expression, and a diverse information environment. Legal challenges to bans and the complexity of enforcement further complicate the issue. The discussion also addresses the broader implications of restricting foreign apps, the role of allies, and the balance between security and civil liberties. Ultimately, the debate underscores a tension between safeguarding national security and preserving an open digital ecosystem, with no consensus on whether a ban is justified or effective.https://cassyni-user-files-prod.s3.amazonaws.com/YH5pdNQfMY6QGGhVAk9JHC https://cassyni.com/slides/outline/Hjmx5KbSwFiEUR7Y4fyQrh https://cassyni.com/events/Hjmx5KbSwFiEUR7Y4fyQrh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5EccTaFZj5iMmm2T5B2BNn https://cassyni.com/events/Hjmx5KbSwFiEUR7Y4fyQrh?videoPreview=1 Information Policy and Management: L3 Managers keep track of relevant uncertaintiesnohttps://cassyni.com/events/Hjmx5KbSwFiEUR7Y4fyQrh?videoPreview=12019-07-26T08:00:00+00:00687.16 School of Public PolicyThis analysis examines the role of managers in organizational contexts as primarily centered on processing information to reduce relevant uncertainties rather than exercising direct authority. Managers are tasked with identifying and addressing diverse uncertainties related to prioritizing problems, allocating appropriate skills, monitoring progress, and linking operational details to strategic goals. The managerial function involves extensive handling of documents, interpreting changes, and reporting their significance within the organizational framework. Variations in managerial experience and information flow depend on industry-specific contexts, such as the rapid operational changes in preventive maintenance versus the slower dynamics of capital account management. Examples from the oil and software industries illustrate how the nature and timing of information influence managerial roles, with decisions ranging from immediate operational choices to longer-term project adaptations. Key information flows include cost accounting, financial monitoring, project design, and authorization tracking, each requiring tailored information processing approaches. Differences in information system stability, the necessity of experiential knowledge, documentation practices, and the scope of information use across organizational units shape the visible form of management but do not alter its fundamental information-processing nature. The study concludes that management’s essence lies in managing information flows to reduce uncertainty, with the specific manifestations of managerial work shaped by the characteristics of the organizational environment and information systems rather than by hierarchical command.https://cassyni-user-files-prod.s3.amazonaws.com/5EccTaFZj5iMmm2T5B2BNn https://cassyni.com/slides/outline/W5z4EQmZuhZ6N6MM32Y8zq https://cassyni.com/events/W5z4EQmZuhZ6N6MM32Y8zq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5XBDPdrcsj72YHjTbnynut https://cassyni.com/events/W5z4EQmZuhZ6N6MM32Y8zq?videoPreview=1 Contributed Paper Session #3nohttps://cassyni.com/events/W5z4EQmZuhZ6N6MM32Y8zq?videoPreview=12013-07-05T08:00:00+00:004363.16 School of Public PolicyThis seminar session addressed ethical, conceptual, and policy challenges at the intersection of biosciences and society through three distinct but thematically linked analyses. The first presentation examined genetically modified (GM) foods as a strategy to mitigate the impact of global climate change on food security and political stability in developing countries. It highlighted the technical and justice-related conditions necessary for GM crops to effectively sever the link between climate change and rising food prices, emphasizing intellectual property regimes and licensing practices exemplified by the Golden Rice case. The analysis underscored the complexity of patent thickets and the potential for royalty-free licensing to facilitate equitable access, while noting persistent cultural and political obstacles to deployment. The second presentation introduced the concept of “deductive risk” in conservation biology, focusing on the definitional plurality of biodiversity and its implications for policy and measurement. It argued that biodiversity is not a singular, well-defined entity but a collection of diverse biological attributes whose operationalization involves value-laden choices. The talk questioned the utility of biodiversity as a policy goal, suggesting species composition might better capture conservation priorities tied to ecosystem services and human values. The third presentation explored social risks posed by neuroscience research, including unequal access to neuroenhancement, privacy violations from neuroimaging, stigmatization linked to neural traits, and threats to human agency. Drawing on Philip Kitcher’s framework of well-ordered science, it distinguished risks amenable to regulation from those requiring radical intervention, ultimately advocating for moderate oversight that balances democratic values with scientific freedom. Collectively, these analyses illuminate the intricate interplay of scientific innovation, ethical considerations, and policy frameworks, highlighting the necessity of integrating technical feasibility with social justice, conceptual clarity, and democratic deliberation in bioscience governance.https://cassyni-user-files-prod.s3.amazonaws.com/5XBDPdrcsj72YHjTbnynut https://cassyni.com/slides/outline/YZE5Tq1C6zKaj2puaiSmim https://cassyni.com/events/YZE5Tq1C6zKaj2puaiSmim/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7DiELKPp5w75DytQ8hTYvJ https://cassyni.com/events/YZE5Tq1C6zKaj2puaiSmim?videoPreview=1 Information-Based Governance and Cross-Border Information Flowsnohttps://cassyni.com/events/YZE5Tq1C6zKaj2puaiSmim?videoPreview=12020-03-09T09:00:00+00:003758.0 School of Public PolicyThis study explores the concept of informational governance as a mode of state influence over public opinion through the shaping, amplification, and filtering of information within domestic and international contexts. It examines how states employ informational tools—ranging from official spokespeople and news media to education and popular culture—to construct narratives that support elite decision-making, particularly in foreign policy. The analysis highlights the tension between state-driven informational governance and societal pushback manifested through independent media, civil society, and dissenting voices empowered by new communication technologies and cross-border information flows. The research foregrounds the role of foreign states in subverting rival states by supporting domestic dissent via informational means, facilitated by the ease of cross-border communication in the digital age. A case study of Russia Today (RT) reveals that, contrary to widespread characterizations as a propaganda outlet, RT functions largely as a platform aggregating diverse dissenting voices, many with credible affiliations, thus complicating simplistic notions of truth and propaganda. Ethical considerations are addressed, focusing on the paradox that truthful information can be subversive and destabilizing, raising questions about the legitimacy and consequences of foreign-supported dissent in stable versus unstable societies. The study calls for nuanced criteria to assess when cross-border informational interventions are ethically justifiable, emphasizing the complex interplay between truth, narrative, social order, and geopolitical interests. This work contributes to understanding the evolving dynamics of information as a tool of governance and subversion in an interconnected global media environment.https://cassyni-user-files-prod.s3.amazonaws.com/7DiELKPp5w75DytQ8hTYvJ https://cassyni.com/slides/outline/Tck2zzXwiQnZKw7ZaEjmzd https://cassyni.com/events/Tck2zzXwiQnZKw7ZaEjmzd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/SYc8FWpQoogoGrVZGvEAxn https://cassyni.com/events/Tck2zzXwiQnZKw7ZaEjmzd?videoPreview=1 AI & Ethics: An Overview of Challenges & Oppportunitiesnohttps://cassyni.com/events/Tck2zzXwiQnZKw7ZaEjmzd?videoPreview=12020-09-15T08:00:00+00:003509.96 School of Public PolicyThe seminar provides a comprehensive overview of ethical challenges and opportunities associated with artificial intelligence (AI), emphasizing near-term, practical concerns rather than speculative existential risks. Key ethical issues discussed include privacy risks arising from AI’s integration with big data, exemplified by cases such as predictive marketing revealing sensitive personal information. Transparency and complexity of AI systems are highlighted, particularly regarding users’ and professionals’ understanding of AI decision-making processes in contexts like medical diagnostics and autonomous vehicles. The phenomenon of AI agents indistinguishable from humans, including chatbots and synthetic personas, raises concerns about deception and trust. The impact of AI on the future of work is examined, focusing on potential job displacement in sectors such as transportation, alongside the need for recalibrating trust in autonomous technologies to avoid over- or under-reliance. Bias in AI, especially in facial recognition systems, is identified as a critical issue, with evidence showing disparities in accuracy across demographic groups, leading to risks of misidentification and discrimination. The ethical implications of AI’s dual-use potential—technologies designed for beneficial purposes that may be repurposed for harm—are also considered. The role of professional organizations, notably IEEE, is discussed in setting ethical guidelines and technical standards to promote responsible AI development aligned with human well-being. The seminar underscores the complexity and evolving nature of AI ethics, advocating for multidisciplinary collaboration among ethicists, engineers, legal experts, and other stakeholders to ensure safe, equitable, and transparent AI systems.https://cassyni-user-files-prod.s3.amazonaws.com/SYc8FWpQoogoGrVZGvEAxn https://cassyni.com/events/2vKpgpBhmX6cAUpq429gJy/seminar/qa https://cassyni.com/events/2vKpgpBhmX6cAUpq429gJy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4UtACcCbHcXe2U6B5trfDx https://cassyni.com/events/2vKpgpBhmX6cAUpq429gJy?videoPreview=1 The African Renaissance and International Cultural Heritage Lawnohttps://cassyni.com/events/2vKpgpBhmX6cAUpq429gJy?videoPreview=12025-10-28T13:00:00+00:003429.04International Journal of Cultural PropertyThis webinar is the opportunity to meet the authors of the special issue on the African Renaissance and International cultural heritage law. This special issue examines how existing legal frameworks can safeguard African cultural heritage, contribute to the African Renaissance, and promote sustainable development. The webinar will be chaired by Valentina Vadi and Senai Woldeab Andemariam, and aims to spark conversations about Africa’s heritage and identify some methods to realize the African Renaissance. Authors will briefly present their contribution across three temporalities: what drew them to the topic, why it is relevant today and what future development they are considering.https://cassyni-user-files-prod.s3.amazonaws.com/4UtACcCbHcXe2U6B5trfDx https://cassyni.com/events/3QyRjVqECyefAFMieTSUaH/seminar/qa https://cassyni.com/slides/outline/3QyRjVqECyefAFMieTSUaH https://cassyni.com/events/3QyRjVqECyefAFMieTSUaH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/L5MTWv1jB6sr3vJCQxFcVU https://cassyni.com/events/3QyRjVqECyefAFMieTSUaH?videoPreview=1 Toward Memristor-Like Resonant Sensors: Pinched Hysteresis Within MEMS Resonatorsnohttps://cassyni.com/events/3QyRjVqECyefAFMieTSUaH?videoPreview=12025-10-15T14:00:00+00:003299.84UK Microsystems Network*Memristors*, uniquely characterized by their pinched hysteresis loop fingerprints, have attracted significant research interest over the past decade, due to their enormous potential for novel computation and artificial intelligence applications. Memristors are widely regarded as the fourth fundamental electrical component, therefore typically exhibit pinched hysteresis purely in the electrical domain, i.e. electrical input and electrical output. In broader terms, similar behavior should also exist in other physical systems across domains (e.g., physical input and electrical output), hence linking the real physical world with the digital domain (e.g., in the form of a physical sensor). In this talk, we share the first observation of **cross-domain pinched hysteresis behavior** in a micro-electro-mechanical systems (MEMS) resonator device, showing that it is viable to create resonant MEMS sensors incorporating memristor-like properties - a new class of MEMS device termed as **MemReSensor**. We will show that these MEMS sensors can have memory, i.e. the output and sensitivity depend on the previous history. We will also show that the pinched hysteresis loop characteristics can be easily tuned by an external electrical signal. We envisage that this will lay the foundations for a new way of fusing MEMS with artificial intelligence (AI), such as creating in-sensor computing, as well as in-sensor AI, e.g., multi-mode in-sensor matrix multiplication across domains.https://cassyni-user-files-prod.s3.amazonaws.com/L5MTWv1jB6sr3vJCQxFcVU https://cassyni.com/events/Dnb7hrRFRbH5gkerfZPNFo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9TDM9aSmRoAxG51UXLaK6W https://cassyni.com/events/Dnb7hrRFRbH5gkerfZPNFo?videoPreview=1 Cosmic-Ray Choreography: How Ion-Driven Instabilities Propel Electron Acceleration and Dictate Ion Transport in Astrophysical Plasmanohttps://cassyni.com/events/Dnb7hrRFRbH5gkerfZPNFo?videoPreview=12024-07-18T06:00:00+00:002827.32Journal of Plasma PhysicsCosmic-ray-driven instabilities are pivotal in accelerating particles at shocks and during the propagation of GeV cosmic rays in galaxies and galaxy clusters. Within the self-confinement picture of cosmic ray (CR) transport, these instabilities amplify magnetic fields, which scatter cosmic rays and self-regulate their movement. This creates a strong coupling between the collisionless cosmic ray population and the thermal background plasma, suggesting potentially significant dynamic feedback. In this talk, I will discuss the inconsistencies between the self-confinement picture in Alfvénic turbulence and certain observations. Attempting to reconcile these inconsistencies by incorporating fast-magnetosonic turbulence cascades requires very fine-tuning to align with the data. I will then introduce a new discovery: a cosmic ray-driven instability termed the intermediate-scale instability. This instability triggers comoving ion-cyclotron electromagnetic waves at sub-ion skin-depth scales and grows notably faster than the resonant ion gyro-scale (streaming) instability, previously considered the dominant instability in the self-confinement model. This breakthrough suggests that the intermediate-scale instability could be crucial in cosmic ray transport in galactic and stellar environments. Next, I will demonstrate how these resonant instabilities saturate in isolation, challenging the fundamental assumptions about saturation in the self-confinement model. This points to a necessary fundamental revision of the theory of CR transport in galaxies and galaxy clusters. Through Particle-in-Cell (PIC) simulations, I will also show that the intermediate-scale instability is the key mechanism for efficient electron injection at parallel electron-ion shocks, addressing the long-standing challenge of electron injection at these shocks. Additionally, the simulations reveal that using reduced ion-to-electron mass ratios in shock simulations, which artificially suppresses the intermediate-scale instability, not only impedes electron acceleration but also leads to incorrect electron and ion heating in downstream and shock transition areas.https://cassyni-user-files-prod.s3.amazonaws.com/9TDM9aSmRoAxG51UXLaK6W https://cassyni.com/events/AL3tP4taMPQSf4MJ1u1Qiy/seminar/qa https://cassyni.com/slides/outline/AL3tP4taMPQSf4MJ1u1Qiy https://cassyni.com/events/AL3tP4taMPQSf4MJ1u1Qiy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/La14ZbfFcZRwiubJvVS934 https://cassyni.com/events/AL3tP4taMPQSf4MJ1u1Qiy?videoPreview=1 Microfluidic and robotic platforms for TME-friendly cancer drug evaluationsnohttps://cassyni.com/events/AL3tP4taMPQSf4MJ1u1Qiy?videoPreview=12025-12-11T16:00:00+00:003931.12UK Microsystems NetworkThere is a lack of confidence in present in vitro disease models and drug efficacy tests, as they do not properly recapitulate the dynamic physiology and pathophysiology of the human organism. This challenge is particularly acute in oncology: present tools to study drug responses fail to faithfully mimic the patient’s tumor microenvironment (TME) and thus have not kept up with tumor biology and drug testing needs. As a measure of this problem, on average less than 4% of oncology drugs in clinical trials end up being FDA-approved, a dismal approval rate that has dire social repercussions such as high cancer drug prices and difficult accessibility. We have developed a suite of microfluidic platforms that address this problem by multiplexing the delivery of drugs to intact-TME human biopsies, altogether bypassing animal testing. We have developed and patented a microdissection methodology that allows for producing large numbers of cuboidal micro-tissues (“cuboids”) from a single tumor biopsy. We have been able to trap cuboids in arrays of microfluidic traps in a 96-well platform and we have developed very high-throughput automated robotic placement of mouse and human cuboids in 384-well plates. With these approaches, it will soon be possible to bypass animal testing and perform direct testing of drugs using only human tumors. Since these new-generation tests preserve the TME intact, we envision that they will minimize FDA failure rates and will contribute to alleviate the cost of cancer drugs. In this talk, I will also cover innovative 3D printing approaches of general applicability to the fabrication of complex biomicrofluidic systems such as organs-on-chips.https://cassyni-user-files-prod.s3.amazonaws.com/La14ZbfFcZRwiubJvVS934 https://cassyni.com/events/CoHucV8CYgAw1zprZav3Su/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2AmKG7a1nAck4M5tZ7H3We https://cassyni.com/events/LD3bRNLxXuQVfMdZmsKYih/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NffiPSjmuPhcW2kUcTSLi2 https://cassyni.com/slides/outline/8r8hMeTtSNfWP7eRQssmho https://cassyni.com/events/8r8hMeTtSNfWP7eRQssmho/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Q1b6XgnaQbpttgFRVYnQgN https://cassyni.com/events/8r8hMeTtSNfWP7eRQssmho?videoPreview=1 The Role of Relief Payments and Premium Subsidies in Optimal Insurance Contractingnohttps://cassyni.com/events/8r8hMeTtSNfWP7eRQssmho?videoPreview=12025-07-06T01:00:00+00:001325.32Risk Sciences[***Risk Sciences***](https://www.keaipublishing.com/en/journals/risk-sciences/) aims to foster diverse, multidisciplinary insights in risk sciences, bridging theory and practice through a series of academic activities. Dr. Jiang's research interests mainly lie in Design of optimal (re)insurance, Risk measures, Clustering of financial assets and Dependence structures. This speech record is an excerpt from Dr. Jiang's keynote speech for the [Risk Sciences Colloquium – 2025 International Workshop on Risk Sharing (IWRS)](https://www.keaipublishing.com/en/journals/risk-sciences/event/2025-international-workshop-on-risk-sharing-iwrs/) , which was held on July 6-7, 2025, in Beijing, China. This video is categorized under ***Catastrophe Risk Sharing***.https://cassyni-user-files-prod.s3.amazonaws.com/Q1b6XgnaQbpttgFRVYnQgN https://cassyni.com/slides/outline/SQdfPm1rWMzd5TWriG9Fj https://cassyni.com/events/SQdfPm1rWMzd5TWriG9Fj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/J2eFpirBNGfNCk3fbdhF7C https://cassyni.com/events/SQdfPm1rWMzd5TWriG9Fj?videoPreview=1 Hydrodynamical simulations of mixed modes in evolved low-mass starsnohttps://cassyni.com/events/SQdfPm1rWMzd5TWriG9Fj?videoPreview=12025-02-19T06:00:00+00:001386.44Leeds Institute for Fluid DynamicsLow-mass evolved stars exhibit a phenomenon known as mixed modes, which originate from the coupling of sound waves in the convective envelope to internal gravity waves in the radiative interior. One can therefore probe features of the deep interior, such as the core rotation rate, from the signatures of the mixed modes at the surface of evolved stars. So far, many observations of mixed modes have been made using CoRoT, Kepler, and TESS, but they have not yet been identified in hydrodynamical simulations. I will present the first simulation revealing the presence of mixed modes in a 1.3M⊙ fully compressible evolved star model. Furthermore, I will attempt to obtain the amplitudes of the mixed modes in our simulations, in an effort to constrain the resulting angular momentum transport, thought to be one of the explanations for the smaller than expected difference in rotation rates between the core and envelope.https://cassyni-user-files-prod.s3.amazonaws.com/J2eFpirBNGfNCk3fbdhF7C https://cassyni.com/slides/outline/3ueetoze3o8Uz1w5QQAmyf https://cassyni.com/events/3ueetoze3o8Uz1w5QQAmyf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/s5fJSn1fBmZJT6DdqHs1Q https://cassyni.com/events/3ueetoze3o8Uz1w5QQAmyf?videoPreview=1 Growth of myelin figures from parent multilamellar dropletsnohttps://cassyni.com/events/3ueetoze3o8Uz1w5QQAmyf?videoPreview=12021-02-24T06:00:00+00:001296.32Leeds Institute for Fluid DynamicsThe study investigates the experimental growth dynamics of myelin figures—tubular multilamellar lipid structures analogous to biological myelin sheaths—originating from parent multilamellar droplets formed by the surfactant linear alkylbenzene sulfonate (LAS). LAS exhibits lyotropic and demotropic phase behavior, transitioning from micellar to lamellar phases upon temperature variation, enabling controlled formation of multilamellar droplets that serve as sources for myelin figure growth. Using optical microscopy and small-angle neutron scattering, the multilamellar droplets were characterized, revealing consistent bilayer spacing (~3 nm) independent of cooling rates, despite variations in droplet size and polydispersity. Time-resolved scattering experiments demonstrated a linear decrease in micellar volume fraction concurrent with linear elongation of myelin figures, indicating a constant volumetric transformation rate from micelles to lamellar structures driving growth. Growth rates inversely correlated with the square of the myelin diameter and increased approximately tenfold with a tenfold increase in cooling rate, supporting a thermodynamically governed mechanism. Dynamic experiments under shear revealed elongation and reversible retraction of myelin figures, alongside instabilities such as buckling and helical motion, highlighting their non-equilibrium behavior. These findings elucidate the interplay between phase transitions, surfactant concentration, and external conditions in controlling myelin figure formation and growth, offering insights relevant to the design of biomimetic multilamellar systems and advancing understanding of amphiphilic self-assembly dynamics.https://cassyni-user-files-prod.s3.amazonaws.com/s5fJSn1fBmZJT6DdqHs1Q https://cassyni.com/slides/outline/Apj7YP3zCCtGUpvemqji8M https://cassyni.com/events/Apj7YP3zCCtGUpvemqji8M/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NYKHSehWa9rrPmjGRGZwLA https://cassyni.com/events/Apj7YP3zCCtGUpvemqji8M?videoPreview=1 Artificial Intelligence in Structural Engineering: From Statistical and Machine Learning to Causal Analysisnohttps://cassyni.com/events/Apj7YP3zCCtGUpvemqji8M?videoPreview=12025-09-16T07:00:00+00:003464.12ArtIStE - Artificial Intelligence in Structural EngineeringCollecting and analyzing empirical data are essential to learning and implementing lessons in structural engineering. Historically, the methods that have been used to analyze and draw conclusions from such data have been limited to statistical and machine learning. The models developed using these techniques are able to capture associative relationships between important variables. However, the intervention decisions geared toward enhancing the resilience of infrastructure should ideally be informed by an understanding of the causal mechanisms that drive their performance. This presentation will advocate for a paradigm shift in structural/earthquake engineering where the language, tools, and models that have been developed to draw causal conclusions from observational data are adopted. Several categories of data-driven structural/earthquake engineering problems that can benefit from causal insights will be examined. Example applications of causal analysis to structural/engineering problems will be highlighted, including case studies where machine learning models are used to establish causal relationships.https://cassyni-user-files-prod.s3.amazonaws.com/NYKHSehWa9rrPmjGRGZwLA https://cassyni.com/events/Mh22g3oRFdzU9aT5fwuqho/seminar/qa https://cassyni.com/slides/outline/Mh22g3oRFdzU9aT5fwuqho https://cassyni.com/events/Mh22g3oRFdzU9aT5fwuqho/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9i6tsMjFRYnLzvrVVRp1tz https://cassyni.com/events/Mh22g3oRFdzU9aT5fwuqho?videoPreview=1 Perturbative model for the saturation of energetic-particle-driven modes limited by self-generated zonal modesnohttps://cassyni.com/events/Mh22g3oRFdzU9aT5fwuqho?videoPreview=12025-11-13T16:00:00+00:002588.56Journal of Plasma PhysicsWe present a simplified energy-conserving approach to incorporate wave-wave nonlinear effects within the framework commonly used to describe wave-particle nonlinearities. In particular, the effects of zonal mode generation on the determination of the saturation amplitude of energetic particle (EP)-driven Alfv´enic instabilities is studied. The model assumes that the zonal perturbations grow at a rate twice that of the original (pump) wave, consistent with a beat-driven (or force-driven) generation mechanism. The evolution and saturation of the mode amplitude are investigated both analytically and numerically within our reduced model assumptions, in both the collisionless and scattering-dominated regimes. These studies underscore the crucial role of sources and sinks in capturing the impact and the role of beat-driven zonal perturbations on mode evolution. In the realistic case of saturation set by sources and sinks, we discuss the role of a finite amplitude zonal mode in reducing microturbulent particle scattering, thus limiting the energy source for the resonant mode. We then discuss comparisons between the model’s predictions and simulation results. The model reproduces key features observed in gyrokinetic simulations as the reduction in saturated mode amplitude and the onset of wave–wave nonlinear effects as functions of mode growth rate and amplitude. Thanks to its simplicity, it can be readily implemented into codes based on reduced models, thereby improving their predictive capability for strongly driven instabilities.https://cassyni-user-files-prod.s3.amazonaws.com/9i6tsMjFRYnLzvrVVRp1tz https://cassyni.com/slides/outline/JEUoMGGkBS7q7t9X2HXtAy https://cassyni.com/events/JEUoMGGkBS7q7t9X2HXtAy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Cn7htJGyB35vky9sURhhgA https://cassyni.com/events/JEUoMGGkBS7q7t9X2HXtAy?videoPreview=1 Evolving with stress: the crucial role of natural antisense transcripts in plant resiliencenohttps://cassyni.com/events/JEUoMGGkBS7q7t9X2HXtAy?videoPreview=12025-08-06T13:30:00+00:00767.56NoneNoncoding DNA regions constitute a substantial portion of eukaryotic genomes, with their transcription playing critical roles in regulating biological processes. Among these, natural antisense transcripts (NATs)—RNA molecules transcribed from the non-template strand of coding DNA—represent an integral yet largely unexplored component of plant genomes. Despite their demonstrated importance, significant knowledge gaps remain in understanding the origins, evolutionary progression, and functional dynamics of NATs. Using interdisciplinary approaches such as molecular phylogenomics and synteny analysis, we uncovered unique genomic distributions of NATs compared to coding genes across various gene families. Notably, transcription factor families exhibited significant variation in NAT abundance, particularly among recently evolved subgroups. Furthermore, differential expression analysis during cold stress underscores the intricate regulatory role of NATs in facilitating environmental adaptation. Moreover, we aim to investigate the promoter regulatory regions to understand the regulatory role of NATs and their contribution to stress adaptation. The findings will redefine the role of noncoding regions in plant genomes, offering novel insights into genome evolution, regulatory networks, and plant resilience. These insights can enable innovative crop engineering strategies to enhance plant resilience, supporting sustainable agriculture and climate change adaptation.https://cassyni-user-files-prod.s3.amazonaws.com/Cn7htJGyB35vky9sURhhgA https://cassyni.com/events/U7StGwDExbC9yQ9YXrJFJu/seminar/qa https://cassyni.com/slides/outline/U7StGwDExbC9yQ9YXrJFJu https://cassyni.com/events/U7StGwDExbC9yQ9YXrJFJu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AQC4R3sacWmq1ckguSCUyU https://cassyni.com/events/U7StGwDExbC9yQ9YXrJFJu?videoPreview=1 Biocides as drivers of antibiotic resistance: A critical review of environmental implications and public health risksnohttps://cassyni.com/events/U7StGwDExbC9yQ9YXrJFJu?videoPreview=12026-01-13T14:00:00+00:003584.68Environmental Science and EcotechnologyBiocides constitute a cornerstone of microbial control strategies in healthcare, food processing, water treatment, and industrial environments. Their broad-spectrum antimicrobial properties, rapid action, and operational flexibility make them indispensable for preventing and/or controlling microbial contamination. Despite their utility, the efficacy of biocides is significantly constrained when confronting microbial biofilms - structured, surface-associated communities encased in an extracellular polymeric matrix. The biofilm phenotype impedes biocide diffusion, fosters physicochemical gradients that induce differential metabolic states, and promotes the survival of tolerant or persister subpopulations. These factors collectively lead to incomplete inactivation, repeated contamination events, and an increased risk of chronic system colonization. Concurrently, the extensive and sometimes sub-optimal use of biocides has raised concerns regarding their role in shaping the environmental resistome. Sublethal biocide exposure, frequently encountered at biofilm interfaces or through improper dosing, can exert selective pressure for adaptive mechanisms, including efflux pump upregulation, alterations in membrane composition, enzymatic detoxification, and activation of the global stress response. Importantly, several of these pathways confer decreased susceptibility not only to biocides but also to structurally or functionally unrelated antibiotics, thereby promoting cross-resistance. Additionally, biocides may co-select antimicrobial resistance genes co-located with biocide tolerance determinants on plasmids, transposons, or integrons, facilitating their persistence and dissemination within microbial communities and across environmental compartments. Evidence of increased tolerance to key clinical antimicrobials following exposure to disinfectants such as quaternary ammonium compounds and chlorhexidine underscores the relevance of these processes for public health. This seminar critically examines the dualistic nature of biocides, as both essential agents for microbial control and potential drivers of resistance evolution. By integrating current knowledge on biofilm tolerance mechanisms, resistome dynamics, and cross-resistance phenomena, it aims to inform risk-benefit assessments and support the development of evidence-based biocide stewardship strategies. https://cassyni-user-files-prod.s3.amazonaws.com/AQC4R3sacWmq1ckguSCUyU https://cassyni.com/slides/outline/LhipagWNNitKUpd5ZySWtu https://cassyni.com/events/LhipagWNNitKUpd5ZySWtu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/33PjbJUY4eep9YTBAMk3re https://cassyni.com/events/LhipagWNNitKUpd5ZySWtu?videoPreview=1 The AI Shake Up: Governance, Graduates, and New Zealand’s Digital Futurenohttps://cassyni.com/events/LhipagWNNitKUpd5ZySWtu?videoPreview=12025-10-14T08:00:00+00:003496.36Business SchoolThe evolving capabilities of artificial intelligence (AI), particularly generative AI models, are reshaping graduate employment, organizational governance, and New Zealand’s digital future. Recent evaluations demonstrate that leading AI systems, such as GPT-4.0 and Claude Opus 4.1, now perform on par with human industry experts across tasks typical of graduate roles in engineering, law, finance, and healthcare. This rapid technological advancement contrasts with slower real-world adoption and highlights a structural shift in the labor market. Empirical data from the US and UK reveal a significant decline in graduate job listings, especially in technology-related fields, linked more to broader economic trends than AI alone. However, AI-driven automation disproportionately affects entry-level roles in finance, ICT, marketing, and customer service, while professions requiring complex judgment and human interaction, such as engineering and healthcare, remain more resilient. AI’s augmentation potential enhances productivity most effectively within diverse teams combining varying expertise levels, emphasizing the importance of collaborative skills alongside AI literacy. For graduates, foundational knowledge, learning agility, and demonstrable AI competencies—including problem-solving, critical thinking, and ethical use—are increasingly vital. Universities face challenges in aligning curricula with rapidly evolving AI capabilities and addressing inequities in AI access and literacy. Employers must balance AI integration with sustainable workforce development, maintaining investment in human capability and governance frameworks that assess AI’s workforce impact. Effective board-level oversight treating AI as both a technological and talent issue is critical to organizational resilience. Ultimately, AI’s impact on employment and governance depends on human choices in adoption and regulation rather than technological determinism.https://cassyni-user-files-prod.s3.amazonaws.com/33PjbJUY4eep9YTBAMk3re https://cassyni.com/events/w5rphvRhKqpSYT2epP7Rw/seminar/qa https://cassyni.com/slides/outline/w5rphvRhKqpSYT2epP7Rw https://cassyni.com/events/w5rphvRhKqpSYT2epP7Rw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6RTzrvX3tRsyq1pu7Nm2A2 https://cassyni.com/events/w5rphvRhKqpSYT2epP7Rw?videoPreview=1 From publications to policy: unpacking Springer Nature and Overton’s latest report on the impact of research on the SDGsnohttps://cassyni.com/events/w5rphvRhKqpSYT2epP7Rw?videoPreview=12026-01-29T12:00:00+00:003375.92Springer Nature Sustainable Development Goals ProgrammeWhat happens when research meets real-world decision-making? Join the co-authors of Springer Nature and Overton’s groundbreaking new report for a deep dive into the most comprehensive analysis to date of how academic research is influencing global policy aligned with the UN Sustainable Development Goals. Drawing on over 12 million policy documents, this session will explore how and where research is being cited in SDG-related policy, what types of content drive the most impact, and why open access and inclusive publishing models matter when it comes to research reach. We’ll walk through the motivations behind the study, key findings, including the role of think tanks and IGOs as knowledge brokers, and what it all means for researchers, institutions, and policymakers striving to accelerate progress towards 2030. Whether you're a researcher aiming to increase the policy relevance of your work, or a policymaker seeking to better understand the evidence base behind SDG strategies, this session offers critical insights into the science-policy interface and how we can strengthen it. The report can be read in full at this [link](https://stories.springernature.com/sdg-impact-report).https://cassyni-user-files-prod.s3.amazonaws.com/6RTzrvX3tRsyq1pu7Nm2A2 https://cassyni.com/events/JjA2WaSA2FbewM92pPerMB/seminar/qa https://cassyni.com/slides/outline/JjA2WaSA2FbewM92pPerMB https://cassyni.com/events/JjA2WaSA2FbewM92pPerMB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RNB46KQ16yS3piShbkU7En https://cassyni.com/events/JjA2WaSA2FbewM92pPerMB?videoPreview=1 AI in Research Assessment, A Global Symposiumnohttps://cassyni.com/events/JjA2WaSA2FbewM92pPerMB?videoPreview=12026-02-11T13:00:00+00:007398.08Research Evaluation and Analytics Capacity HubThe Research Evaluation Group (INORMS) and the REACH Network are pleased to invite you to a Global Symposium on “AI in Research Assessment”, taking place 11 February 2026. This event brings together leading voices in research policy and evaluation, to explore one of the most urgent questions facing the scholarly community: **Can AI assess research?** Artificial intelligence promises to reshape how research is evaluated. Emerging AI tools can generate detailed, human-like assessment - opening exciting opportunities to reduce administrative burden, support evaluation at scale, and uncover new insights. At the same time, these technologies raise concerns around accuracy, transparency, equity, and the protection of research integrity. The symposium arrives at a moment when the global research community is already rethinking evaluation practices. As assessment evolves beyond narrow bibliometric indicators, researchers and institutions increasingly recognize the importance of mentorship, open science, societal and economic contributions, and collaborative work. How might AI support these responsible approaches - and under what safeguards? Our aim is to engage critically with both the promise and the pitfalls of AI-assisted evaluation, asking: • When can AI meaningfully contribute to research assessment? • What standards, governance, and oversight are required? • Which tasks should remain firmly in the hands of peer-review? **AI in Research Assessment: Friend or Foe for Research Integrity?** Dr. Maura Hiney The interplay between research assessment and research integrity is complex. Robust research integrity practices ensure trust and quality in the direct products of research (outputs) and the subsequent use and effects of these outputs (outcomes and impacts). In such an environment, honest and fair assessment is supported. However, when research integrity fails, assessors may be basing their judgements on biased, poor-quality, or untrustworthy outputs and outcomes. In addition, assessing individuals whose research practices are poor or who are willing to cheat to advance their careers may skew the assessment system in their favour and disadvantage those striving for quality in their research. Adding AI tools to an already complex relationship raises the question of whether using such tools in research assessment will help or hinder research integrity practices. **Can Large Language Models Be Used Responsibly in Research Assessment?** Dr. Mike Thelwall Large Language Models (LLMs) are already being used in research assessment by at least one funder, as well as by some conferences and journals. In all cases they support but do not replace human judgment. Recent evidence also suggests that LLMs are moderately good at assessing the quality of published academic research, even based only on titles and abstracts. Given the huge burden of various forms of peer and expert review in academia, it is tempting to suggest that shortcuts and timesaving must be possible. This is already happening because LLMs are secretly used by many reviewers to replace their opinion, even if the journal, conference, or funder tells them not to. This practice has probably increased the risk that flawed research passes peer review and good research is blocked. More generally, all uses of LLMs in research assessment must be considered carefully from various perspectives, including biases, perverse incentives, and the practical outcomes of greater reliance on AI. For example, if AI becomes more important, will authors prioritize studies that they expect ChatGPT to like, such as those singing the praises of AI or with exaggerated value claims? **Bridging Research and AI for Impact Narratives** Dr. Diego Emilio Lozano Qualitative peer review for researchers is inherently time-consuming, demanding substantial effort for reviewer training and process standardization to ensure robust and unbiased evaluations. To address this, the University of Monterrey (UDEM) conducted a control exercise: 80 researchers were evaluated by five independent peer reviewers to mitigate human bias and establish a reliable average score. Subsequently, we tested an AI tool as a potential replacement for multiple human evaluators. While the AI excelled at generating critical textual analysis, it was ultimately found to be incapable of delivering a reliable, direct quantitative assessment. Our final, successful approach redefined the AI’s role: the tool now rapidly analyzes complex research documents and generates structured, focused validation questions for the human evaluator. This transformation shifts the evaluator's task from deep review to efficient verification. This AI-augmented workflow significantly accelerates the joint validation of impact narratives. The conclusive model positions the AI not as a substitute, but as a critical support mechanism, projecting a sustainable reduction in required human evaluators from five to just two. **Panel Session Includes** Dr. Elizabeth (Lizzie) Gadd, Loughborough University Dr. Julia Melkers, Arizona State University https://cassyni-user-files-prod.s3.amazonaws.com/RNB46KQ16yS3piShbkU7En https://cassyni.com/events/KDodZG5gTi9hw7fvQpwecV/seminar/qa https://cassyni.com/slides/outline/KDodZG5gTi9hw7fvQpwecV https://cassyni.com/events/KDodZG5gTi9hw7fvQpwecV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BFRteWzxKj8eTL6s8tw5mQ https://cassyni.com/events/KDodZG5gTi9hw7fvQpwecV?videoPreview=1 TRAIL Induces Cytokine Production via the NFkB2 Pathway Promoting Neutrophil Chemotaxis and Neutrophil-Mediated Immune-Suppression in Triple Negative Breast Cancer Cellsnohttps://cassyni.com/events/KDodZG5gTi9hw7fvQpwecV?videoPreview=12026-02-19T19:00:00+00:003632.2Center for Cancer TrainingTumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a potential cancer therapeutic that induces apoptosis in cancer cells while sparing the non-malignant cells in preclinical models. However, its efficacy in clinical trials has been limited, suggesting unknown mechanisms modulating TRAIL activity in patients. We hypothesized that TRAIL treatment elicits transcriptional changes in triple negative breast cancer (TNBC) cells that alter the immune milieu. RNAseq analysis of MDA-MB-231 cells along with validation in additional cell lines demonstrated that TRAIL induced cytokines such as CXCLs 1, 2, 3, 8,11 and IL-6, which are known to modify neutrophil function. Mechanistically, TRAIL dependent induction of the cytokines was predominantly mediated by death receptor 5, caspase-8 and the non-canonical NFKB2 pathway. These cytokines produced by TRAIL-treated TNBC cells enhanced chemotaxis of normal human donor isolated neutrophils. Using TNBC xenograft models, TRAIL induced activation of NFkB2 pathway, cytokine production and increased neutrophil recruitment into the tumors. Moreover, preincubation of neutrophils in supernatants from TRAIL-treated TNBC cells significantly impaired neutrophil function as measured by reduced respiratory burst and cytotoxic effect against TNBC cells. Transcriptomic analysis of neutrophils incubated with either TRAIL alone or supernatant of TRAIL-treated TNBC cells revealed increased expression of inflammatory cytokines, immune modulatory genes, immune checkpoint genes, and genes implicated in delayed neutrophil apoptosis. Functional studies showed that these neutrophils suppress T cell proliferation and augment Treg suppressive phenotype. Collectively, our study demonstrates a novel role of TRAIL-induced NFKB2-dependent cytokine production that promotes neutrophil chemotaxis and neutrophil-mediated immune suppression.https://cassyni-user-files-prod.s3.amazonaws.com/BFRteWzxKj8eTL6s8tw5mQ https://cassyni.com/events/VbRKXcfhgKn8Tcy4RvtYJ1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/64Q5rGkGRxPkf4NoXBLJ9L https://cassyni.com/events/Uc87SFNeoQfyns94KxRDV7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/MG2iooDqWNErWKp2bL4tyU https://cassyni.com/events/DnHGSvkVzd665VzSXK4WJy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2CAVvB6m5zu8UgEi52Uvxn https://cassyni.com/events/MC2xFoyFyrKeiZDJmkrgMb/seminar/qa https://cassyni.com/slides/outline/MC2xFoyFyrKeiZDJmkrgMb https://cassyni.com/events/MC2xFoyFyrKeiZDJmkrgMb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/SihGkWkvbeWQDJ2K5DrHR8 https://cassyni.com/events/MC2xFoyFyrKeiZDJmkrgMb?videoPreview=1 Advances in intelligent machines and autonomy and your thoughts on research needs and gapsnohttps://cassyni.com/events/MC2xFoyFyrKeiZDJmkrgMb?videoPreview=12026-06-18T16:30:00+00:003856.72AIAA JournalThe panel will discuss diverse topics and issues related to the development of autonomous capabilities, their enabling technologies – including artificial intelligence (AI), and their application to aerospace and robotic systems more generally. Some specific topics include: - Constraints on currently fielded autonomous capabilities; - Roles for contemporary AI in design, development, and operations of robotic vehicle systems; - Limitations on the use of AI in safety-critical applications; - Establishing trust in AI methods; - Issues with the certification of autonomous capabilities using established methods and processes; and, - The evolutionary traits needed for AI methods to render trusted, acceptable judgment in the performance of complex missions by autonomous robotic systems; … to name a few. The audience will be afforded a live question-answer period at the conclusion of panel presentations.https://cassyni-user-files-prod.s3.amazonaws.com/SihGkWkvbeWQDJ2K5DrHR8 https://cassyni.com/slides/outline/RdsPfxnyvyJuBCy6gQdFW5 https://cassyni.com/events/RdsPfxnyvyJuBCy6gQdFW5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JB82hyEPPemQfJH2rZGja6 https://cassyni.com/events/RdsPfxnyvyJuBCy6gQdFW5?videoPreview=1 Enhancing C₄ photosynthesis for carbon capture and food securitynohttps://cassyni.com/events/RdsPfxnyvyJuBCy6gQdFW5?videoPreview=12025-08-06T10:00:00+00:001787.24NoneC₄ plants, which perform C₄ photosynthesis, often dominate hot and arid regions around the world, and C₄ crops are becoming increasingly important for global food and bioenergy security. This is due to the presence of a specialized C₄ metabolic cycle that functions as a biochemical carbon-concentrating mechanism, enabling Rubisco, the primary carbon-fixing enzyme, to operate near its maximum efficiency. Although C₄ plants already exhibit high rates of carbon fixation, further improvements in C₄ photosynthesis could further enhance carbon capture and increase crop yields. Using the model species Setaria viridis and the multipurpose crop Sorghum bicolor, we have tested multiple strategies to enhance carbon fixation under various environmental conditions. Our findings demonstrate that improving C₄ photosynthesis is a tractable strategy for increasing crop productivity, supporting rising food and energy demands, and contributing to climate change mitigation through enhanced carbon capture.https://cassyni-user-files-prod.s3.amazonaws.com/JB82hyEPPemQfJH2rZGja6 https://cassyni.com/events/S6nQU6GRYB11XDFkdKx5j/seminar/qa https://cassyni.com/slides/outline/S6nQU6GRYB11XDFkdKx5j https://cassyni.com/events/S6nQU6GRYB11XDFkdKx5j/abstract https://cassyni-user-files-prod.s3.amazonaws.com/31gpfSyKbrbp3ECncmnrna https://cassyni.com/events/S6nQU6GRYB11XDFkdKx5j?videoPreview=1 Ingestion of terrestrial plastic pollution by free-roaming livestock, including working donkeys: an interdisciplinary assessmentnohttps://cassyni.com/events/S6nQU6GRYB11XDFkdKx5j?videoPreview=12026-04-01T13:00:00+00:001735.56Cambridge PrismsIn areas where waste management is inadequate, the welfare of free-roaming animals can be significantly affected by the ingestion of plastic waste, potentially impacting human livelihoods and health. However, the effect of plastic pollution on terrestrial animals is poorly understood. Using a combination of methodologies from animal behaviour, environmental and social sciences, this study assesses the effects of plastic pollution on donkeys, cattle and their owners in Kenya. Behavioural observations suggested that donkeys and cattle preferentially fed at waste sites, where 1 in every 10–20 items ingested were plastic. Faecal sampling also showed much higher concentrations of microplastics than those reported in previous studies of farmed cattle and significantly higher concentrations in the faeces of donkeys and cattle grazing at waste sites compared to rural areas. Survey data showed that the majority of livestock owners believed that plastic pollution was a problem, and nearly a third of local residents had witnessed an animal becoming ill following plastic ingestion, reporting mortality rates of 78%. Triangulating data from multiple methods highlights the risks terrestrial plastic pollution poses to domestic animals, demonstrating the need for interdisciplinary projects that tackle this important issue by addressing the interconnectedness of human behaviour, animal welfare and environmental health.https://cassyni-user-files-prod.s3.amazonaws.com/31gpfSyKbrbp3ECncmnrna https://cassyni.com/events/GFYunyW1bGnMG8vdGfoJwo/seminar/qa https://cassyni.com/slides/outline/GFYunyW1bGnMG8vdGfoJwo https://cassyni.com/events/GFYunyW1bGnMG8vdGfoJwo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/R2QpdZXt8qsMWSoV5M8uin https://cassyni.com/events/GFYunyW1bGnMG8vdGfoJwo?videoPreview=1 Metaoptics-based optomechanicsnohttps://cassyni.com/events/GFYunyW1bGnMG8vdGfoJwo?videoPreview=12026-05-12T13:00:00+00:003648.48MetaMATThis seminar explores the integration of metaoptics concepts into optomechanical systems, enabling precise control over light-matter interactions and optical forces. The work highlights two main thrusts: the development of mechanically reconfigurable metaoptics and the manipulation of optical forces for levitation optomechanics. An optomechanically reconfigurable metalens, fabricated from a 200-nanometer-thick silicon membrane patterned with meta-atoms, demonstrates focal distance tuning via optomechanical deformation induced by a pump beam, exhibiting a response time of approximately 15 microseconds. Additionally, a study on suspended silicon metasurfaces investigates engineering the sign of optical forces. By tuning meta-atom parameters, control over the effective polarizability is achieved, allowing solid matter to be attracted to intensity minima in a standing wave, a phenomenon referred to as dark trapping. This capability is further extended to levitated optomechanics, where silicon nanoparticles with tailored multipole resonances are trapped in standing waves, enabling manipulation of trapping frequencies and depths. Hybrid metalenses integrating silicon-on-insulator structures with gold electrodes are also developed for levitated particle cooling, achieving temperatures of a few tens of phonons. These advancements offer new opportunities for quantum physics, high-precision sensors, transducers, and the exploration of surface effects by controlling particle proximity to surfaces.https://cassyni-user-files-prod.s3.amazonaws.com/R2QpdZXt8qsMWSoV5M8uin https://cassyni.com/slides/outline/MgiBR88fpfoUY2CpZryeXo https://cassyni.com/events/MgiBR88fpfoUY2CpZryeXo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BSRcJawruUAjedgbjZMznA https://cassyni.com/events/MgiBR88fpfoUY2CpZryeXo?videoPreview=1 Mathematical Imaging in the Era of AInohttps://cassyni.com/events/MgiBR88fpfoUY2CpZryeXo?videoPreview=12026-04-16T12:00:00+00:004023.04MOX Laboratory - Department of MathematicsMathematical imaging has for decades been a powerful catalyst for new developments across the mathematical sciences. At its core lie fundamental questions about how information can be represented, reconstructed, and interpreted from incomplete, noisy, or indirect data. Addressing these questions has led to deep advances in areas such as functional and harmonic analysis, geometry, variational methods, inverse problems, partial differential equations, probability and statistics, and, more recently, learning theory. The resulting interplay between theory, computation, and applications has made imaging a uniquely fertile meeting point for pure and applied mathematics alike. Applications span an extraordinary range of domains, including biomedical and materials imaging, astronomy, environmental science, cultural heritage, and emerging technologies such as autonomous systems and data-driven diagnostics. The rapid rise of artificial intelligence is now reshaping the landscape of imaging science once again. Data-driven approaches, in particular deep learning, have achieved remarkable empirical success in tasks such as reconstruction, segmentation, and synthesis. At the same time, their opaque nature and heavy reliance on data raise fundamental mathematical questions concerning stability, generalisation, interpretability, uncertainty quantification, and the incorporation of prior knowledge and physical constraints. In this talk, I will present mathematical imaging as a continuing source of new mathematical ideas and challenges in the age of AI. I will highlight how modern approaches seek to blend data-driven models with structure, geometry, and physical principles, giving rise to novel analytical frameworks and computational paradigms. This perspective positions imaging not merely as an application area, but as a driver for the next generation of mathematical theory at the interface of analysis, computation, and learning.https://cassyni-user-files-prod.s3.amazonaws.com/BSRcJawruUAjedgbjZMznA https://cassyni.com/events/6sG42civewBrE5v7ZD9uz5/seminar/qa https://cassyni.com/slides/outline/6sG42civewBrE5v7ZD9uz5 https://cassyni.com/events/6sG42civewBrE5v7ZD9uz5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WKdJjVbH9ZmtMHXL4Q3z22 https://cassyni.com/events/6sG42civewBrE5v7ZD9uz5?videoPreview=1 Combustion Technologies for Waste Treatment: Latest Developmentsnohttps://cassyni.com/events/6sG42civewBrE5v7ZD9uz5?videoPreview=12026-04-17T11:00:00+00:003378.24Waste Management JournalWaste-to-Energy (WtE) plants operate at the intersection of energy production, environmental compliance, and circular economy. They are complex industrial systems, characterized by high variability in input materials, strict regulatory constraints, and the need for continuous operation. A2A has adopted Artificial Intelligence not as a research initiative, but as an operational enabler to improve plant performance, availability, and environmental outcomes across its Waste-to-Energy fleet. Here we share experience with AI, highlighting: the strategic rationale behind its adoption; the main application areas already in use; concrete results achieved; and the future direction toward collaboration and shared innovation. A2A is the Italian market leader in material and energy recovery from waste, operating 11 Waste-to-Energy plants distributed across the country. At this scale, even small improvements in efficiency and availability generate significant economic and environmental value. Waste-to-Energy plants are inherently complex: waste composition varies continuously; combustion and flue-gas treatment processes are highly non-linear; maintenance activities have a direct impact on availability and revenues. Traditional rule-based control and threshold-based monitoring are no longer sufficient to manage this complexity efficiently. Artificial Intelligence enables: data-driven decision making; early detection of anomalies and degradation; predictive rather than reactive maintenance; better integration with energy markets. AI is not optional innovation, but a necessary tool to operate WtE plants at industrial scale. A2A’s AI journey is part of a broader digital transformation strategy based on three pillars: 1. Data availability through increased digitalization of plants and assets, 2. Data governance to ensure quality, consistency, and accessibility, 3. Artificial Intelligence to transform data into actionable insights. Without robust data governance, AI cannot deliver value. For this reason, A2A invested in standardizing data collection, structuring information flows, and building scalable architectures shared across plants. A2A’s AI applications in Waste-to-Energy focus on three main areas: 1. Anomaly Detection and Predictive Maintenance 2. Energy Forecasting and Market Integration 3. Generative AI for Documentation and Compliance Each area addresses a different dimension of plant performance and risk management. A2A’s experience highlights a few key lessons: AI delivers value only when embedded in operations; data governance is as important as model sophistication; human-in-the-loop approaches increase trust and adoption; cross-domain reuse accelerates maturity; accelerate innovation on shared challenges.https://cassyni-user-files-prod.s3.amazonaws.com/WKdJjVbH9ZmtMHXL4Q3z22 https://cassyni.com/events/7Muf5JNT6PjuDrT19eSiFP/seminar/qa https://cassyni.com/slides/outline/7Muf5JNT6PjuDrT19eSiFP https://cassyni.com/events/7Muf5JNT6PjuDrT19eSiFP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RJVw8mBw8Tx28uihSVF3FU https://cassyni.com/events/7Muf5JNT6PjuDrT19eSiFP?videoPreview=1 Reverse-osmosis permeate isn’t always clean enough – Needs for municipal and industrial wastewater reusenohttps://cassyni.com/events/7Muf5JNT6PjuDrT19eSiFP?videoPreview=12026-05-11T15:00:00+00:003573.2ElsevierMunicipal and industrial wastewater reuse applications are expanding and producing high value clean water for a wide range of uses. Reverse osmosis (RO) membrane treatment provides an excellent barrier to many organic compounds and inorganic salts. The permeate can therefore be used for applications that range from potable reuse to semiconductor ultrapure makeup water. However, low molecular weight neutral organic chemicals such as urea, alcohols, aldehydes, ketones, solvents, and certain disinfection byproducts including trihalomethanes (THMs) and NDMA are often poorly rejected by RO membranes and can remain in the permeate. The presence of these compounds may limit reuse options. This presentation explains why these compounds are poorly removed and focuses on strategies to mineralize them in RO permeate. Experimental results and validated models based on advanced oxidation processes will be presented. These processes employ a range of radical chemistry approaches generated by far UV to visible light under both homogeneous and heterogeneous catalytic conditions. The presentation aims to advance understanding of the science while also highlighting the challenges and limitations of radical chemistry for municipal and industrial wastewater reuse applications that rely on reverse osmosis.https://cassyni-user-files-prod.s3.amazonaws.com/RJVw8mBw8Tx28uihSVF3FU https://cassyni.com/slides/outline/4Q3euq1Bs1M61d8xJ6Bitm https://cassyni.com/events/4Q3euq1Bs1M61d8xJ6Bitm/abstract https://cassyni-user-files-prod.s3.amazonaws.com/544EyGdpv8QVSy517fzakv https://cassyni.com/events/4Q3euq1Bs1M61d8xJ6Bitm?videoPreview=1 Multi-hazard risk assessment for prioritization of existing bridge portfolios nohttps://cassyni.com/events/4Q3euq1Bs1M61d8xJ6Bitm?videoPreview=12025-10-20T06:00:00+00:001117.84NoneIn recent years, several catastrophic collapses of existing bridges have highlighted the need for rapid risk analysis methods aimed at supporting infrastructure managers in the prioritisation of detailed assessments and, if any, risk mitigation actions. A large percentage of existing road bridges were built between the 1960s and 1980s, having thus already reached or even exceeded their design lifetime. Several studies have also shown that bridges often collapse due to either natural or human-related events, such as floods, collisions or overloading that, in addition to earthquakes, should be duly considered in risk assessment. This calls for multi-hazard approaches that provide an integrated perspective of the risk of bridge portfolios, to identify critical struc tures to support decision-makers. This study proposes a multi-hazard risk-based prioritisation methodology for application to a large number of bridges under limited level of knowledge. Specifically, the risk level is quantified through indices, accounting for uncertainties, that are used for comparative purposes among bridges. The methodology is applied to a highway bridge portfolio located in northern Italy, producing a risk-based ranking that is critically discussed. Analysis results are then compared with the outcome of the current Italian guidelines for safety assessment and maintenance of existing bridges.https://cassyni-user-files-prod.s3.amazonaws.com/544EyGdpv8QVSy517fzakv https://cassyni.com/slides/outline/CJSwmPsUHh8kKyEn1umki9 https://cassyni.com/events/CJSwmPsUHh8kKyEn1umki9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6bGtkLRV4mTLSovuTjY3En https://cassyni.com/events/CJSwmPsUHh8kKyEn1umki9?videoPreview=1 Pressure to explore new worlds, exotic solids, and star powernohttps://cassyni.com/events/CJSwmPsUHh8kKyEn1umki9?videoPreview=12026-06-11T15:00:00+00:003359.84Journal of Plasma PhysicsA science revolution is underway with the discovery of thousands of planets outside of our solar system, the creation of revolutionary materials, and the potential for harnessing fusion energy. Unlocking these discoveries hinges on our ability to understand and manipulate matter to and beyond atomic pressures, conditions that alter the nature of atoms themselves. At such conditions our intuition for matter begins to breakdown, with hydrogen becoming a metal and perhaps a superconducting superfluid, water becoming superionic where protons flow through a compact oxygen crystal, and unbound electrons getting squeezed interior to core orbitals of an atom. I will show how laboratory laser experiments are opening this science frontier at light speed, revealing how we might make transparent aluminum-like in Star Trek, a new exploration into the nature and implications of planets-potential platforms for life throughout the universe, and controlled thermonuclear fusion. You might take a look at one of our videos as a primer to our discussion (https://www.youtube.com/watch?v=NqabT21d8VM). https://cassyni-user-files-prod.s3.amazonaws.com/6bGtkLRV4mTLSovuTjY3En https://cassyni.com/events/AKk389DpvRDT3ogssegYn9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VYPbdFX6S7Kj26b3LkBZRG https://cassyni.com/slides/outline/Cnz4MZTT7hywQkASRLbBW5 https://cassyni.com/events/Cnz4MZTT7hywQkASRLbBW5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EjqF59JQeYTvpQvD5TyY9L https://cassyni.com/events/Cnz4MZTT7hywQkASRLbBW5?videoPreview=1 Session 3B: Emerging Electrolyses Technologynohttps://cassyni.com/events/Cnz4MZTT7hywQkASRLbBW5?videoPreview=12025-10-22T06:00:00+00:005676.64Centre for Energy TechnologyThis seminar session critically appraises emerging electrolysis technologies addressing the urgent need for scalable, cost-effective green hydrogen production to support climate goals and renewable energy integration. Three innovative approaches were presented: a rotating reversible fuel cell (RFC) employing artificial gravity to enhance gas bubble removal and electrode utilization, achieving up to fivefold increased hydrogen production per electrode area with significantly reduced size, capital expenditure (CAPEX), and operating expenditure (OPEX); a solar-driven modular system integrating commercial photovoltaics with air-fed, moisture-absorbing electrolysis cells designed for direct coupling to variable renewable energy sources, enabling rapid dynamic response and simplified balance-of-plant, resulting in fourfold lower energy costs and flexible grid operation; and a medium-temperature (100–150 °C) electrolyzer based on a mesoporous ceramic membrane grown on porous supports, allowing high current densities (>0.5 A/cm²) at low voltage (~1.6 V) without precious metal catalysts, with scalable planar and tubular configurations offering improved efficiency, reduced membrane thickness, and enhanced operational flexibility. Key challenges identified include membrane durability and lifetime validation, scale-up and automation for manufacturing, market acceptance, and securing pilot-scale funding amid policy and financial uncertainties. The session underscores the importance of system-level innovation beyond stack optimization, integration with renewable energy variability, and the need for supportive funding mechanisms to bridge the “valley of death” in technology deployment. Collectively, these advances demonstrate promising pathways toward compact, efficient, and flexible electrolysis solutions critical for accelerating the hydrogen economy and grid balancing applications.https://cassyni-user-files-prod.s3.amazonaws.com/EjqF59JQeYTvpQvD5TyY9L https://cassyni.com/events/PfGyVECtB9695VgsKSmK5X/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XBYiqft9nKSaJXUL3UMkAz https://cassyni.com/events/PAjru4cuM8EwzimCv1wtHb/seminar/qa https://cassyni.com/slides/outline/PAjru4cuM8EwzimCv1wtHb https://cassyni.com/events/PAjru4cuM8EwzimCv1wtHb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DnZEAWC1bdK98WnaY32GEi https://cassyni.com/events/PAjru4cuM8EwzimCv1wtHb?videoPreview=1 Publishing in Ecology & Evolution: An Editor’s Perspectivenohttps://cassyni.com/events/PAjru4cuM8EwzimCv1wtHb?videoPreview=12026-07-22T14:00:00+00:003371.68Ecology and Evolution Stop by to meet Arley Muth, Co-Editor-in-Chief of Ecology and Evolution. Arley will be available to answer your questions about the publication process, the journal, and related topics. Image credit: [Erick Morales Oyola (Unsplash)](https://unsplash.com/photos/kelp-forest-underwater-with-sunlight-beams-vHDLjO-iW8k).https://cassyni-user-files-prod.s3.amazonaws.com/DnZEAWC1bdK98WnaY32GEi https://cassyni.com/slides/outline/WaMS8oGEKYqvaJgSgtLFED https://cassyni.com/events/WaMS8oGEKYqvaJgSgtLFED/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QP3KFAvVWK47CXtVJtVmk2 https://cassyni.com/events/WaMS8oGEKYqvaJgSgtLFED?videoPreview=1 Powering Progress: Technology, Policy, and Innovation Across U.S. Regionsnohttps://cassyni.com/events/WaMS8oGEKYqvaJgSgtLFED?videoPreview=12025-09-22T08:00:00+00:004230.6 School of Public PolicyIn this Energy Policy Seminar, Dr. Marilyn A. Brown used the Georgia Tech-National Energy Modeling System (GT-NEMS 2023) to examine how collections of policy initiatives could interact and how regions might differentially respond.https://cassyni-user-files-prod.s3.amazonaws.com/QP3KFAvVWK47CXtVJtVmk2 https://cassyni.com/slides/outline/3uLodtKtcpwVNTgpJKEaof https://cassyni.com/events/3uLodtKtcpwVNTgpJKEaof/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Xz4bzzKbDHpAPG8WfoBPjL https://cassyni.com/events/3uLodtKtcpwVNTgpJKEaof?videoPreview=1 Nano TransMed Youth Forum 2025, Session IIInohttps://cassyni.com/events/3uLodtKtcpwVNTgpJKEaof?videoPreview=12025-10-22T01:00:00+00:004103.92None[Nano TransMed (NTM)](https://www.keaipublishing.com/en/journals/nano-transmed/) is an open access peer-reviewed journal. To promote cross-boundary research and linkage between nanotechnology and clinical applications, as well as to build an inclusive, barrier-free communication platform for emerging talent in the community, NTM brings together young scholars across the field to share real-time cutting-edge technologies and the latest research findings. 2025 Session III was held on Oct. 22, 2025. Two speakers shared their latest research.https://cassyni-user-files-prod.s3.amazonaws.com/Xz4bzzKbDHpAPG8WfoBPjL https://cassyni.com/slides/outline/BK4sL92mChFKs3DHGC6KDf https://cassyni.com/events/BK4sL92mChFKs3DHGC6KDf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/R7HT4ddHHxMr4dLnt6CcA2 https://cassyni.com/events/BK4sL92mChFKs3DHGC6KDf?videoPreview=1 Collaboration Powers – Empowers! – Peer Review (Lightning Talk)nohttps://cassyni.com/events/BK4sL92mChFKs3DHGC6KDf?videoPreview=12026-02-24T13:00:00+00:00461.52Researcher to ReaderRising submission volumes, research integrity pressures, and rapid technological and workflow changes are reshaping peer review. Embracing this depends on collaboration, empathy and understanding of shared roles across the research publishing ecosystem. This talk shares practical change management insights to build accountability, readiness and trust for sustainable, future-ready peer review.https://cassyni-user-files-prod.s3.amazonaws.com/R7HT4ddHHxMr4dLnt6CcA2 https://cassyni.com/slides/outline/JEAx6LbzkTvqWKuFvCbgzy https://cassyni.com/events/JEAx6LbzkTvqWKuFvCbgzy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/XQTnisUCUyJQBfiXo2kQkW https://cassyni.com/events/JEAx6LbzkTvqWKuFvCbgzy?videoPreview=1 C4 – Building Connections: Institutional Strategies for Integrating PIDs, Identity, and Expertise Visibilitynohttps://cassyni.com/events/JEAx6LbzkTvqWKuFvCbgzy?videoPreview=12026-04-20T12:30:00+00:002921.68Research Analytics SummitUnderstanding and communicating the full scope of an institution's research activity requires reliable, interoperable data about scholars, outputs, and impact. In this session, we present case studies from Indiana University (IU) Bloomington, IU Indianapolis, and Oklahoma State University that demonstrate how Persistent Identifiers (PIDs) like ORCID iDs provide infrastructure that makes institutional expertise visible, trustworthy, shareable, and analyzable. We will highlight strategies for increasing ORCID adoption among researchers and connecting PIDs to existing enterprise systems as we aspire to use PID-enriched data to surface insights about collaboration networks, disciplinary strengths, and research impact within and across research institutions. Attendees will gain a clearer understanding of the organizational, technical, and cultural considerations involved in building a sustainable, PID-driven research information ecosystem, as well as practical approaches that can be adapted for their own institutional contexts.https://cassyni-user-files-prod.s3.amazonaws.com/XQTnisUCUyJQBfiXo2kQkW https://cassyni.com/events/HjcDPYW8X69sbrWyK6x6J9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DzSVng6pwwjt94FrcxDH58 https://cassyni.com/events/LhQyKkqcwkhKsGNpTtWKiu/abstract https://cassyni-user-files-prod.s3.amazonaws.com/SZ5gMbyTRZxNHPUqmamnV4 https://cassyni.com/events/MgrHzGi6qUS7GiGfxYHBv5/seminar/qa https://cassyni.com/slides/outline/MgrHzGi6qUS7GiGfxYHBv5 https://cassyni.com/events/MgrHzGi6qUS7GiGfxYHBv5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Xy2p7HNAWRsnj7Ehu4vxsQ https://cassyni.com/events/MgrHzGi6qUS7GiGfxYHBv5?videoPreview=1 Virus, Vaccine, Village: Science and Society's Influence on the 2026 Bundibugyo Ebola Outbreaknohttps://cassyni.com/events/MgrHzGi6qUS7GiGfxYHBv5?videoPreview=12026-08-12T17:00:00+00:004146.72Journal of VirologyJoin us for the next Journal of Virology Seminar Series where Elizabeth Talbot, MD and Elizabeth Wrobel, PhD. will discuss the 2026 Bundibugyo ebolavirus outbreak in the Democratic Republic of Congo (DRC) and Uganda — its epidemiology, the accelerated push for vaccines, therapeutics, and diagnostics, and the conflict-driven barriers shaping the response on the ground.The 2026 Bundibugyo Ebola outbreak in the DRC and Uganda is unfolding without the medical toolkit that has helped contain past Ebola epidemics - no licensed vaccine, no approved treatment, and only slow, infrastructure-heavy lab testing. At the same time, the response is playing out in one of the world's most fragile settings: an active conflict zone marked by deep community distrust, attacks on health workers, and a health system already stretched before the outbreak began.   This webinar brings together the epidemiology of the outbreak, the accelerated push to develop vaccines, therapeutics, and rapid diagnostics for an historically neglected virus species, and the cultural and structural forces shaping whether those tools can actually reach the people who need them. Participants will leave with a grounded, current understanding of both the science and the on-the-ground realities driving this response. **Learning Objectives:** *By the end of this webinar, participants will be able to:* + Describe the epidemiology of the 2026 Bundibugyo virus disease outbreak, including its transmission dynamics, geographic spread, and how it compares to prior Ebola epidemics. + Summarize the current status of vaccine, therapeutic, and diagnostic development for Bundibugyo virus, including why existing Zaire-strain countermeasures don't reliably transfer and which candidates are furthest along. + Identify the structural and cultural barriers - including armed conflict, community distrust, and health workforce strain - that are shaping the effectiveness of the outbreak response. + Explain how scientific and social factors interact, and why closing the medical countermeasure gap alone will not be sufficient to control the outbreak without addressing trust and access.https://cassyni-user-files-prod.s3.amazonaws.com/Xy2p7HNAWRsnj7Ehu4vxsQ https://cassyni.com/slides/outline/LhZ5tuR3xZKxbxSfrZos7B https://cassyni.com/events/LhZ5tuR3xZKxbxSfrZos7B/abstract https://cassyni-user-files-prod.s3.amazonaws.com/JmSgNP7nQobe7R5LQmX4H4 https://cassyni.com/events/vv88vq7HAHTZgGcwQkTeD/seminar/qa https://cassyni.com/slides/outline/vv88vq7HAHTZgGcwQkTeD https://cassyni.com/events/vv88vq7HAHTZgGcwQkTeD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DvZB8nRbDrq7tg2FSsqhWn https://cassyni.com/events/vv88vq7HAHTZgGcwQkTeD?videoPreview=1 Single-cell glycomics of the pancreatic tumor microenvironment: decoding glyco-immune checkpoints and tumor–immune communicationnohttps://cassyni.com/events/vv88vq7HAHTZgGcwQkTeD?videoPreview=12026-09-10T09:00:00+00:003101.0Advanced SciencePancreatic cancer presents severe therapeutic resistance and a 5-year survival rate below 10%, driven largely by an immunosuppressive tumor microenvironment (TME). Because conventional techniques are restricted to bulk samples, single-cell glycan and RNA sequencing (scGR-seq) employs DNA-barcoded lectins to convert glycan profiles into amplifiable nucleic acid information for simultaneous transcriptomic profiling. Applying scGR-seq and the computational platform GlycoChat to pancreatic cancer tissues reveals that surface glycans undergo extensive remodeling during the epithelial-to-mesenchymal transition (EMT). Classical epithelial subtypes exhibit high expression of $\alpha$2-6 sialic acid, $\alpha$1-2/4 fucose, and Core2, whereas basal-like mesenchymal subtypes highly express $\alpha$2-3 sialic acid, bisecting GlcNAc, and Tn antigen. This single-cell resolution facilitates translational applications, such as identifying the fucosylated O-glycan H-type 3 ligand for rBC2LCN, which enabled the development of lectin-drug conjugates and the early-stage serum biomarker BC2-S3 (rBC2LCN-positive SERPINA3) that shows higher detection rates than CA19-9. At the systems level, GlycoChat decodes complex glycan-lectin interaction networks in the TME, demonstrating that communication between cancer cells and immune cells increases during EMT. Specifically, basal-like cancer cells exhibit strong interactions with tumor-associated macrophages via CLEC10A and SIGLEC3 pathways. Experimental co-culture assays demonstrate that these interactions induce immunosuppressive M2 macrophage polarization and suppress macrophage-mediated phagocytosis. These EMT-driven glyco-immune checkpoints correlate with poor patient prognosis, establishing a foundation for glyco-state biology and targeted glyco-immunotherapies.https://cassyni-user-files-prod.s3.amazonaws.com/DvZB8nRbDrq7tg2FSsqhWn https://cassyni.com/events/V6SF7NqYQY7K2bjHXjqNwo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QX6HaQxhKg51PScuf5Zffk https://cassyni.com/slides/outline/vn1ZnFgGMeppzCmYjSvFw https://cassyni.com/events/vn1ZnFgGMeppzCmYjSvFw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4jjjxL3kzQSSVWazNE1Lri https://cassyni.com/events/vn1ZnFgGMeppzCmYjSvFw?videoPreview=1 Creative Writing and AI: A 2024 Case Studynohttps://cassyni.com/events/vn1ZnFgGMeppzCmYjSvFw?videoPreview=12026-03-18T12:59:08+00:001859.64Public HumanitiesThis paper analyzes the 2024 Mellichamp Mind and Machine Initiative at UCSB, a pioneering AI-inclusive literary competition accepting human, AI, and hybrid works. As Head Judge, I explore key questions confronting the panel: Will AI render human writing obsolete? Can machine-generated literature exhibit creativity or remain mechanical? Are AI and human writing distinguishable? What does authorship mean in an era of AI collaboration?https://cassyni-user-files-prod.s3.amazonaws.com/4jjjxL3kzQSSVWazNE1Lri https://cassyni.com/events/GkE8xHfRS6GB5bv94mvH81/seminar/qa https://cassyni.com/slides/outline/GkE8xHfRS6GB5bv94mvH81 https://cassyni.com/events/GkE8xHfRS6GB5bv94mvH81/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VuCmX8oD3uZoyYmMhWXRpS https://cassyni.com/events/GkE8xHfRS6GB5bv94mvH81?videoPreview=1 How to review a journal article: An APA Journals webinar for the Japanese Psychological Association nohttps://cassyni.com/events/GkE8xHfRS6GB5bv94mvH81?videoPreview=12026-05-21T11:00:00+00:003398.44NoneJoin this interactive webinar, intended for the Japanese Psychological Association (JPA) members, to learn about peer review, how to become an APA Journals reviewer, and how to access APA Journals reviewer resources. Dr. Pim Cuijpers, Editor of the [*Journal of Consulting and Clinical Psychology*](https://www.apa.org/pubs/journals/ccp) will share his expertise and provide tips for international reviewers. Image credit: [Christin Hume (Unsplash)](https://unsplash.com/photos/person-using-laptop-computer-Hcfwew744z4). Image credit: [Corinne Kutz (Unsplash)](https://unsplash.com/photos/person-using-laptop-computer-beside-aloe-vera-tMI2_-r5Nfo).https://cassyni-user-files-prod.s3.amazonaws.com/VuCmX8oD3uZoyYmMhWXRpS https://cassyni.com/slides/outline/UbpGBKhuNSUzBJtoDsV2K7 https://cassyni.com/events/UbpGBKhuNSUzBJtoDsV2K7/abstract https://cassyni-user-files-prod.s3.amazonaws.com/L7XZE8sLnASXUkExQQd3Rx https://cassyni.com/events/UbpGBKhuNSUzBJtoDsV2K7?videoPreview=1 Blocking the Competition: Superinfection Inhibition by Giant Virusesnohttps://cassyni.com/events/UbpGBKhuNSUzBJtoDsV2K7?videoPreview=12025-07-21T13:00:00+00:003574.2Journal of VirologyCatch up on the latest webinar in the Journal of Virology Seminar Series, featuring Isabella Aquino, Ph.D., M.S., as she explores the newly identified phenomenon of superinfection inhibition in giant viruses that infect amoebas—specifically mimivirus and moumouvirus. In this talk, Aquino presents compelling evidence that these viruses can prevent subsequent infections by blocking additional viral particles from entering the same host cell, a strategy notably absent in megavirus. Her findings shed light on the complex competitive dynamics between viruses and offer fresh insights into how these interactions shape virus-host relationships, evolutionary pathways, and broader ecological systems. https://cassyni-user-files-prod.s3.amazonaws.com/L7XZE8sLnASXUkExQQd3Rx https://cassyni.com/slides/outline/7ratEcXrwDDj3KSWwkZgRb https://cassyni.com/events/7ratEcXrwDDj3KSWwkZgRb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/T2KZ8U74zRaxDVXRFYAjMQ https://cassyni.com/events/7ratEcXrwDDj3KSWwkZgRb?videoPreview=1 Black Entrepreneurs and Business Loan Attitudesnohttps://cassyni.com/events/7ratEcXrwDDj3KSWwkZgRb?videoPreview=12025-11-19T17:00:00+00:00831.52Center for Black Entrepreneurship, Spelman CollegeThe study addresses the often-overlooked "invisible hesitation" experienced by Black entrepreneurs when seeking business loans, arguing it is as impactful as visible structural barriers in limiting business growth and affecting the broader economy. Grounded in institutional theory and the behavioral theory of the firm, a sequential exploratory mixed-methods design was employed. Qualitative data from entrepreneurs, lawyers, and bank employees informed the development of a quantitative Likert-style survey. This survey measured the impact of perceived formal (economic, financial, regulatory) and informal institutional barriers (encompassing community support, knowledge, aversion to knowledge, and self-directed perception) on Black entrepreneurs' loan confidence, comfort with larger loan amounts, and perceived likelihood of approval. Results indicate that perceived institutional barriers significantly reduce overall loan confidence. Specifically, perceived formal barriers negatively impacted loan application confidence and the likelihood of approval, but not the loan amount sought. Perceived informal institutional barriers demonstrated even stronger and more widespread negative effects across all three dependent variables. These findings underscore the importance of fostering self-confidence and knowledge among Black entrepreneurs. They also highlight the crucial role of lenders and support organizations in providing clear information and building a supportive bridge to knowledge. The research concludes that addressing cognitive, interpretive, and community-based processes is essential, alongside structural changes, as entrepreneurs not only face institutional barriers but also internalize and feel them.https://cassyni-user-files-prod.s3.amazonaws.com/T2KZ8U74zRaxDVXRFYAjMQ https://cassyni.com/events/EmfLtBbD5cyWY8S6KC8caH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NQfZbLRGffTh8XRtjcUcB8 https://cassyni.com/events/EmfLtBbD5cyWY8S6KC8caH?videoPreview=1 The ‘Magic’ of Boron in Programming Precision Peptide Functionnohttps://cassyni.com/events/EmfLtBbD5cyWY8S6KC8caH?videoPreview=12026-02-25T09:00:00+00:003122.08Thieme India ChemTalksAbstract not yet added.https://cassyni-user-files-prod.s3.amazonaws.com/NQfZbLRGffTh8XRtjcUcB8 https://cassyni.com/events/FGJwvsEjX5XZXtxyudRQqb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CympJPtBDCDaHJyYL3jjnv https://cassyni.com/slides/outline/9qBJRM7xh3SV92ikJiRcr9 https://cassyni.com/events/9qBJRM7xh3SV92ikJiRcr9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3SkxgVLAPfvtycJJDrLUj8 https://cassyni.com/events/9qBJRM7xh3SV92ikJiRcr9?videoPreview=1 Publishing with Advanced Journalsnohttps://cassyni.com/events/9qBJRM7xh3SV92ikJiRcr9?videoPreview=12026-04-29T01:00:00+00:003744.04Advanced ScienceIn this publishing workshop for early‑career researchers and established faculty, I will share an editor’s perspective on how scientific papers are evaluated, published, and amplified. Drawing on my experience across Wiley, Nature, and Cell Press, the session will demystify how editorial decisions are made and what distinguishes strong submissions in a competitive publishing landscape.https://cassyni-user-files-prod.s3.amazonaws.com/3SkxgVLAPfvtycJJDrLUj8 https://cassyni.com/slides/outline/T7u59uHDTRkNduXV2ZbVFs https://cassyni.com/events/T7u59uHDTRkNduXV2ZbVFs/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PcyGGCGoK2qSWNLzQSAAKp https://cassyni.com/events/T7u59uHDTRkNduXV2ZbVFs?videoPreview=1 KeAi Talk: ISWCR Series IV_Prof. Paolo Tarollinohttps://cassyni.com/events/T7u59uHDTRkNduXV2ZbVFs?videoPreview=12026-04-21T01:00:00+00:001091.72NoneNature-based Solutions and Modelling Innovations for Sustainable Soil and Water Management under Climate Extremes [International Soil and Water Conservation Research (ISWCR)](https://www.keaipublishing.com/en/journals/international-soil-and-water-conservation-research/), the official journal of the [World Association of Soil and Water Conservation (WASWAC)](http://www.waswac.org.cn), is a multidisciplinary journal for soil and water conservation research, practice, policy, and perspectives. This journal aims to disseminate new knowledge and promote the practice of soil and water conservation. https://cassyni-user-files-prod.s3.amazonaws.com/PcyGGCGoK2qSWNLzQSAAKp https://cassyni.com/events/W5pKYdgFVXzjVXknHTWpSH/seminar/qa https://cassyni.com/slides/outline/W5pKYdgFVXzjVXknHTWpSH https://cassyni.com/events/W5pKYdgFVXzjVXknHTWpSH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2dp4qWmBS37HcKEvxQFRRG https://cassyni.com/events/W5pKYdgFVXzjVXknHTWpSH?videoPreview=1 Introducing npj Thermal Science and Engineeringnohttps://cassyni.com/events/W5pKYdgFVXzjVXknHTWpSH?videoPreview=12026-06-30T15:00:00+00:002547.96NoneWelcome to the inaugural webinar for npj Thermal Science and Engineering.https://cassyni-user-files-prod.s3.amazonaws.com/2dp4qWmBS37HcKEvxQFRRG https://cassyni.com/slides/outline/R9LH5oD16xTi6S3SGyopi9 https://cassyni.com/events/R9LH5oD16xTi6S3SGyopi9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2FbnL7tAcd3BfupYFRuEmt https://cassyni.com/events/R9LH5oD16xTi6S3SGyopi9?videoPreview=1 Remote sensing of stress impacts on plant metabolismnohttps://cassyni.com/events/R9LH5oD16xTi6S3SGyopi9?videoPreview=12026-06-05T08:00:00+00:002012.88Remote sensing is transforming the way we monitor the physiological impacts of environmental stress on vegetation. Under rising temperatures, recurrent droughts and more frequent heatwaves, hyperspectral and thermal imaging provide complementary information on plant metabolism, including pigment regulation, water status, stomatal control, photosynthetic functioning and canopy energy balance. These approaches are particularly valuable for detecting stress before visual symptoms become evident, supporting a shift from retrospective forest assessment towards early warning. This plenary lecture will provide an overview of how hyperspectral-thermal remote sensing can be used to assess physiological alterations caused by water and heat stress in declining forests. The talk will discuss the potential of UAV/drone, airborne and satellite platforms, highlighting their complementary roles across spatial scales: from individual-tree assessment using very high-resolution data to regional monitoring and long-term satellite time series. To translate spectral and thermal signals into quantitative information on physiological variables, however, physically based radiative transfer models are needed. These models provide the link between sensor observations and plant function by simulating how leaf and canopy traits control reflected, emitted and fluoresced radiation. Their inversion enables the retrieval of key functional traits, such as pigment pools, leaf water and dry matter content, LAI and photosynthetic capacity, while thermal indicators provide insight into stomatal regulation and evaporative cooling. As an applied example, the lecture will present recent work in Mediterranean oak forests of the southwest Iberian Peninsula, where hyperspectral and thermal imagery, radiative transfer modelling and thermal time series were used to detect early water-stress signals linked to oak declinehttps://cassyni-user-files-prod.s3.amazonaws.com/2FbnL7tAcd3BfupYFRuEmt https://cassyni.com/slides/outline/8MHjWZDABPdKgnUVuN89js https://cassyni.com/events/8MHjWZDABPdKgnUVuN89js/abstract https://cassyni-user-files-prod.s3.amazonaws.com/kxBHSEeBAV3KhmCpnpyx2 https://cassyni.com/events/8MHjWZDABPdKgnUVuN89js?videoPreview=1 Welcome to the Symposium nohttps://cassyni.com/events/8MHjWZDABPdKgnUVuN89js?videoPreview=12026-06-02T11:05:00+00:001419.0The 47th New Phytologist Symposium addresses the critical challenge of extreme heat, which increasingly shapes plant performance, agriculture, and ecosystem stability globally. Heat extremes, no longer abstract future concerns, are now landscape shocks, occurring ten times more frequently than in the 1960s. Global temperatures have risen approximately 1.5°C from pre-industrial levels, with the last three years being the warmest on record. Temperatures exceeding 50°C pose a life-threatening risk by denaturing proteins and melting cellular membranes. While achieving net zero carbon emissions is vital to halt further warming, models indicate that future heat is already locked into the Earth system for centuries, necessitating significant adaptation strategies. The symposium, hosted in Córdoba—a city with historical and ongoing experience with heat extremes—explores both traditional adaptations, such as microclimate management, strategic crop timing, and biodiversity use, and contemporary scientific approaches. It aims to connect scientific knowledge with real-world challenges by fostering open discussion, identifying knowledge gaps, and catalyzing solutions. Key areas include molecular physiology, biochemical aspects of heat tolerance, water use for cooling, and modelling heatwaves. Future directions focus on plant-microbe-insect interactions under hot conditions, designing heat-resilient food and landscape systems, leveraging remote sensing, and exploring innovative interventions like gene editing for enhanced heat tolerance. The goal is to move from understanding mechanisms to developing actionable, coordinated solutions through multinational collaboration, including global experimental frameworks for "heatwave chasing."https://cassyni-user-files-prod.s3.amazonaws.com/kxBHSEeBAV3KhmCpnpyx2 https://cassyni.com/events/Co8Avi2t8Wca9SEHp1titM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/V4wxteNcLryLGrdQh1BoNN https://cassyni.com/events/6NiwST8wpvLf9JzT9nLVC9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LHS5aAowhUHsUydLSqVnoY https://cassyni.com/events/BKCyuHcCDVsxbjH8esPrbw/seminar/qa https://cassyni.com/slides/outline/BKCyuHcCDVsxbjH8esPrbw https://cassyni.com/events/BKCyuHcCDVsxbjH8esPrbw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6ytF5JA94JmBkF3bL97T66 https://cassyni.com/events/BKCyuHcCDVsxbjH8esPrbw?videoPreview=1 Aggregate Science - Part 1nohttps://cassyni.com/events/BKCyuHcCDVsxbjH8esPrbw?videoPreview=12026-09-18T08:00:00+00:003443.84Small Structures JournalFor centuries, molecular science has been guided by reductionism, with researchers focusing primarily on the properties of matter at the level of individual molecules. Yet, recent advances in aggregation-induced emission (AIE) research have introduced a transformative paradigm: aggregate science. This emerging field shifts the focus toward collective behaviors and emergent properties arising from interacting molecular systems, offering a more holistic framework for scientific exploration. By moving beyond reductionist constraints, aggregate science unlocks new frontiers of discovery. This seminar series will highlight its far-reaching implications across disciplines — from nanomaterials and optoelectronics to biomedical theranostics and beyond. Through a multidimensional lens, we seek to propel this integrative approach, fostering a paradigm shift in scientific research and revealing deeper insights into complex systems.https://cassyni-user-files-prod.s3.amazonaws.com/6ytF5JA94JmBkF3bL97T66 https://cassyni.com/events/JEK4fVBRmGZUF1y7JsuEPF/seminar/qa https://cassyni.com/slides/outline/JEK4fVBRmGZUF1y7JsuEPF https://cassyni.com/events/JEK4fVBRmGZUF1y7JsuEPF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7kFr32bnKGsETSR4GrjCQW https://cassyni.com/events/JEK4fVBRmGZUF1y7JsuEPF?videoPreview=1 On the role of mutualisms in plant biogeography: consequences for ecology, evolution, and invasionnohttps://cassyni.com/events/JEK4fVBRmGZUF1y7JsuEPF?videoPreview=12026-09-04T13:30:00+00:002839.32New PhytologistMost plant species world-wide depend on one or more mutualisms – beneficial associations with other species. Evidence is emerging that these biotic mutualisms shape plant biogeography (i.e. distributions). In particular, the absence of these mutualist partners limits plant establishment (i.e. the mutualist filter). Moreover, this mutualism filter has subsequent consequences for plant ecology, evolution, and invasion. However, a review of such evidence and a synthesis of mechanisms underpinning the mutualist filter are lacking. Therefore, here, I present evidence for the mutualist filter, discuss ecological and evolutionary consequences of this filter, and develop a synthetic framework, generating several cross-mutualist predictions of mutualist filter strength. The mutualist filter should increase with higher mutualist dispersal limitation, specificity and dependency of association, and an increasing number of mutualisms. Together, this offers a path to shift our abiotic and antagonistic centric perspective in plant biogeography to integrate these pervasive mutualistic biotic interactions.https://cassyni-user-files-prod.s3.amazonaws.com/7kFr32bnKGsETSR4GrjCQW https://cassyni.com/slides/outline/V6aMgXQyRLjwmHo8vR8vL5 https://cassyni.com/events/V6aMgXQyRLjwmHo8vR8vL5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9YQzUxptu75gNoH2tBsR8S https://cassyni.com/events/V6aMgXQyRLjwmHo8vR8vL5?videoPreview=1 Bootstrap Current Modeling in M3D-C1 with Application to Nonlinear MHD Modeling of the Helios Stellarator Design nohttps://cassyni.com/events/V6aMgXQyRLjwmHo8vR8vL5?videoPreview=12026-08-13T15:00:00+00:001913.12Journal of Plasma PhysicsAccurate modeling of the bootstrap current is essential for understanding the magnetohydrodynamic (MHD) equilibrium and stability of magnetically confined plasmas, where it can represent bulk of the electric current density. This work expands the modeling capabilities of M3D-C1, an extended-MHD code, to self-consistently calculate the bootstrap current in 3D geometries by implementing two analytical frameworks, the generalized Sauter (Sauter et al., 1999) and revised Sauter-like model (Redl et al., 2021), the latter of which is adapted for quasisymmetric (QS) stellarators via an isomorphism framework (Landreman et al., 2022). Benchmarking against neoclassical codes (NEO, XGCa, and SFINCS) shows excellent agreement. These enhanced bootstrap current modeling capabilities are applied to analyze the stability of Thea Energy Inc.’s Helios stellarator: a two-field-period, quasi-axisymmetric configuration with an 8 m major radius, aspect ratio $A = 4.5$, and on-axis field $B = 6 T$. The nonlinear M3D-C1 simulations demonstrate that the pressure profile remains robust through 2000 Alfvén times with saturated low-amplitude ballooning modes, indicating that core confinement properties are preserved despite a slightly chaotic edge region. **This paper was selected as one of JPP's Featured Articles by a combined vote of our Editorial Board and Advisory Board. Please see [here](https://www.cambridge.org/core/journals/journal-of-plasma-physics/featured-articles) for more information.**https://cassyni-user-files-prod.s3.amazonaws.com/9YQzUxptu75gNoH2tBsR8S https://cassyni.com/events/BotD4bmc4KMnRCGeSyWpn9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PzTou8vsXj2RZa2hFWfGVk https://cassyni.com/events/QAZuAPhnstwzngmSK9RjRf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/G2RZT5dmTBqXHMyAMWoxEr https://cassyni.com/events/7sAxdqMUPnfz7M4wwgGxgd/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VZgLQ42vepNW8UCGqerWUv https://cassyni.com/events/EnFRHQQpYCRmcA4XK7qtqK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/3Gf6GhDxwnayitCSNGsCii https://cassyni.com/events/NC176HdaXRfLFDHPZZe4sw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Jeu1pzsE3Dp9F43vPhDNi2 https://cassyni.com/slides/outline/S8t6Cq92c7uVRvfVnGWamB https://cassyni.com/events/S8t6Cq92c7uVRvfVnGWamB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Yc8pGAzNmPwiU1hQ8iNgmt https://cassyni.com/events/S8t6Cq92c7uVRvfVnGWamB?videoPreview=1 Cyber Risk in Connected Systems: Insights from Modeling and Behaviornohttps://cassyni.com/events/S8t6Cq92c7uVRvfVnGWamB?videoPreview=12025-09-30T01:00:00+00:003700.04Risk SciencesThis seminar series is jointly organized by [***World Salon***](https://www.world-salon.com/) and [***Risk Science***](https://www.keaipublishing.com/en/journals/risk-sciences/) Prof. Dr. Martin Eling is Full Professor of Insurance Economics and holds the Chair for Insurance Management at the University of St. Gallen, where he also serves as Director of the Institute of Insurance Economics. His empirical research spans insurance management, mathematics, and economics, focusing in recent years on cyber risk, risk measurement, regulation, digitalization, and systemic vulnerabilities in financial and insurance markets. He earned his doctorate in 2005 at the University of Münster and has held appointments in Ulm and as a visiting professor in the USA, among others. Prof. Eling is a prolific author, advisor, and speaker, widely recognized for his work on the insurability of emerging risks, regulatory frameworks like Solvency II, and the quantitative modeling of risk in interconnected systems. Dr. Petar Jevtic is an Associate Professor in the School of Mathematical and Statistical Sciences at Arizona State University, with affiliations in the Center for Biodiversity Outcomes. He holds a Ph.D. in Economics with specialization in Applied Mathematics and Statistics from the University of Turin, along with degrees in Economics and Computer Science and Engineering from Belgrade. His research spans longevity risk, property & casualty insurance, cyber risk, smart contract and autonomous systems risk, and climate‑induced risk. He has published in leading journals, holds patents in cyber risk modeling and pricing, and his work is supported by grants from bodies such as the NSF, DHS, and Society of Actuaries. Amir Ansari is Chief Technology Advisor at Lenovo, where he leads advanced services strategy across EMEA, focusing on AI, Big Data, and cloud-driven transformations for enterprise and public sector clients. With deep expertise in architecting secure, data-centric solutions, Amir has spearheaded initiatives across Smart Cities, Defense, Healthcare, and Education—deploying edge and hybrid cloud strategies that reduce data latency, enforce local data residency, and integrate cybersecurity frameworks such as ISO 27001, NIST, and GDPR. As a trusted advisor to CxOs, Amir has guided organizations in navigating the intersection of innovation and risk, embedding security and compliance into AI, IoT, and edge ecosystems while enabling operational efficiency gains of up to 40%. He is passionate about helping organizations address the rising cyber risks in connected systems by designing resilient architectures that balance agility, compliance, and digital trust. Dr. Yevgeniy Vorobeychik joined Washington University in St. Louis in 2018. He was an assistant professor of computer science and biomedical informatics at Vanderbilt University from 2013 until 2018, and a principal research scientist at Sandia National Laboratories from 2010 until 2013. Between 2008 and 2010 he was a post-doctoral research associate at the University of Pennsylvania Computer and Information Science department. He received a PhD and MSE in Computer Science and Engineering from the University of Michigan and a BS degree in Computer Engineering from Northwestern University. Professor Vorobeychik received an NSF CAREER award in 2017 and was invited to give an IJCAI-16 early career spotlight talk. He was nominated for the 2008 ACM Doctoral Dissertation Award and received honorable mention for the 2008 IFAAMAS Distinguished Dissertation Award. Dr. Linfeng Zhang is an Assistant Professor in the Department of Mathematics at The Ohio State University, specializing in actuarial science and risk analytics. He earned his Ph.D. in Mathematics from the University of Illinois at Urbana–Champaign and is an Associate of the Society of Actuaries. Before joining Ohio State, he served as a Visiting Assistant Professor of Actuarial Science at Drake University and gained industry-oriented research experience at the Critical Infrastructure Resilience Institute, focusing on cyber risk and cyber insurance. His research explores cyber risk, pandemic risk, and privacy risk, with publications in leading journals such as The Geneva Papers on Risk and Insurance, IEEE Transactions on Emerging Topics in Computing, and the Connecticut Insurance Law Journal. He has led and contributed to projects funded by the Society of Actuaries, Fundación MAPFRE, and Cisco, and continues to advance interdisciplinary approaches to risk management and actuarial science.https://cassyni-user-files-prod.s3.amazonaws.com/Yc8pGAzNmPwiU1hQ8iNgmt https://cassyni.com/events/Y4P7cjkTr1HQ31Eq33JUz1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/RmcDrGZsJs6sexFKPugxUn https://cassyni.com/slides/outline/W5gCyV6pUjN6kqgvtnDH41 https://cassyni.com/events/W5gCyV6pUjN6kqgvtnDH41/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QjZ2JpVv74MdxJjB9qMYH4 https://cassyni.com/events/W5gCyV6pUjN6kqgvtnDH41?videoPreview=1 A Comparative Study on Eco-feminism and A Principle of Sympathetic Resonancenohttps://cassyni.com/events/W5gCyV6pUjN6kqgvtnDH41?videoPreview=12022-11-28T12:00:00+00:004997.12Hong Kong Baptist UniversitySince the early 1970's, theorists working in the area of feminist science have questioned the historical and sociological relationships between gender and science. Their critique is part of a more general questioning of science and technology which casts doubt as to whether they alone hold the solutions to the world's problems such as environmental degradation, unemployment and war. They revisit Francis Bacon on the ways he exemplifies the sexual task of science is the exercise of (male) domination over Nature (female). This talk reviews the gendered character of contemporary science summarized by feminists and traces its root and its subject and object modality back to Greek philosophy. It also examines Ecofeminism as "a new term for an ancient wisdom" which embodies an integration of the liberation movements. The talk follows the view that the Chinese I-Ching (the Book of Changes) provides a powerful example of a philosophy of life which described the duality of existence based upon the masculine and feminine principles. It seeks harmony through the balance of these complementary aspects. It concludes with the metaphysics of harmony and conflict in the I-Ching and that the presence of antagonism demands a moral and practical transformation of humans. The talk also brings in comparative considerations that Eco-feminism may want to consider.https://cassyni-user-files-prod.s3.amazonaws.com/QjZ2JpVv74MdxJjB9qMYH4 https://cassyni.com/slides/outline/R9CAWeda69q5MjyatJWHKs https://cassyni.com/events/R9CAWeda69q5MjyatJWHKs/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DiUc27PosHP6uuo66r7F6e https://cassyni.com/events/R9CAWeda69q5MjyatJWHKs?videoPreview=1 The Document on Rain: Predicting with Weather in Early Han Chinanohttps://cassyni.com/events/R9CAWeda69q5MjyatJWHKs?videoPreview=12020-11-05T12:00:00+00:005329.04Hong Kong Baptist UniversityThe Document on Rain (yushu 雨書) is a short manuscript that forms part of the Beijing University collection of Han slips. This text, divided into two sections, has thus far garnered little scholarly attention, however, it presents to us an unusual example of a daybook-type manuscript, one which is primarily concerned with the weather. The Document on Rain, while sharing many characteristics of excavated daybooks, is unique in its treatment of humans. Rather than providing advice on whether or not one should undertake activity on a certain day, or engaging in the discourse about whether or not humans can manipulate the weather, the Document on Rain takes a transcendent view, presenting to us an unfamiliar form of prognostication, which does not allow humans to take control of their own fate, as well as an understanding of weather as a phenomenon that cannot be manipulated by humans. In so doing, the Document on Rain attempts to integrate practices of prognostication based on calendrical and sexagenary cycles with theories about rain and its relationship to the twenty-eight stellar lodges. In this paper, I will discuss the integration of astro-meteorological knowledge into mantic understandings of the world as behaving in predictable calendrical cycles.https://cassyni-user-files-prod.s3.amazonaws.com/DiUc27PosHP6uuo66r7F6e https://cassyni.com/events/MhfMJXeoWwJBYz94wiNf3T/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Vgo5zJfdh2GFhfCW6N3H4r https://cassyni.com/slides/outline/4u2jL4qM8o1uSeNjCHEtEy https://cassyni.com/events/4u2jL4qM8o1uSeNjCHEtEy/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Lwb4N8AyUx1drkxqrfQr3p https://cassyni.com/events/4u2jL4qM8o1uSeNjCHEtEy?videoPreview=1 ARIA: a song of air beyond the Anthropocenenohttps://cassyni.com/events/4u2jL4qM8o1uSeNjCHEtEy?videoPreview=12020-12-05T12:00:00+00:001511.92Hong Kong Baptist UniversityA discussion with with composer Eugene Birman and artist Kingsley Ng about ARIA, a multi-disciplinary research project that premiered at the Forsgate Conservatory in Hong Kong Park November 2020. The production featured vocal performances, dance and light installations that explored air and the impact of environmental pollution.https://cassyni-user-files-prod.s3.amazonaws.com/Lwb4N8AyUx1drkxqrfQr3p https://cassyni.com/slides/outline/2Rni6ebiwWFR5huAebLFX3 https://cassyni.com/events/2Rni6ebiwWFR5huAebLFX3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2ynVdHNfWGbusqFgfFWonE https://cassyni.com/events/2Rni6ebiwWFR5huAebLFX3?videoPreview=1 Commencement Celebration for 2020 Graduatesnohttps://cassyni.com/events/2Rni6ebiwWFR5huAebLFX3?videoPreview=12020-11-21T12:00:00+00:004388.52Hong Kong Baptist UniversityThis abstract summarises the Commencement Celebration for the 2020 Graduates of the Faculty of Arts at Hong Kong Baptist University. The event served as a belated, in-person recognition of graduates' achievements, held in the context of the COVID-19 pandemic and prior social unrest that had led to earlier ceremony cancellations. Various faculty leaders and department heads delivered welcoming remarks and messages of encouragement. Themes highlighted included the resilience of graduates in overcoming challenges, the importance of developing critical thinking and communication skills, and the integration of "head" (critical theory) and "heart" (emotions, creative writing) for holistic personal development. Graduates were encouraged to embrace their role as "survivors," viewing their degree as a foundation for a new journey marked by ambition, continuous learning, and contributions to society. The celebration also featured diverse performances by students and faculty, including musical acts and a multi-lingual play on translation and interpreting. The proceedings underscored the enduring value of community, face-to-face interaction, and the university's role as a lifelong home for its alumni, while equipping graduates with the skills and mindset to shape a hopeful future.https://cassyni-user-files-prod.s3.amazonaws.com/2ynVdHNfWGbusqFgfFWonE https://cassyni.com/slides/outline/DJ417gqGbaRtbyjCG8ZwTs https://cassyni.com/events/DJ417gqGbaRtbyjCG8ZwTs/abstract https://cassyni-user-files-prod.s3.amazonaws.com/QuzHJyRHz7NSMHDNXvXs3c https://cassyni.com/events/DJ417gqGbaRtbyjCG8ZwTs?videoPreview=1 The Ethical and Social Implications of AI in Asianohttps://cassyni.com/events/DJ417gqGbaRtbyjCG8ZwTs?videoPreview=12022-05-09T12:00:00+00:004007.48Hong Kong Baptist UniversityDr. Levi Checketts is associate professor of religion and philosophy at Hong Kong Baptist University. A 2018 graduate of the GTU and recipient of the Charles H. Townes Fellowship, his research focuses on Catholic social ethics and new technologies. He leads a committee on AI concerns from an Asian perspective for the Pontifical Council for Culture and serves as Networking Fellow for AI and Faith. He has a forthcoming two volume edited work Theology and Technology from Wipf and Stock and is currently writing a book on AI epistemology and the preferential option for the poor.https://cassyni-user-files-prod.s3.amazonaws.com/QuzHJyRHz7NSMHDNXvXs3c https://cassyni.com/slides/outline/FmJ2M74tnsCNxvCkopUaBo https://cassyni.com/events/FmJ2M74tnsCNxvCkopUaBo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CkYuAGdP5aAoVjBKSBvQ6z https://cassyni.com/events/FmJ2M74tnsCNxvCkopUaBo?videoPreview=1 Images of Macau: East-West Exchange and The Derwent Collectionnohttps://cassyni.com/events/FmJ2M74tnsCNxvCkopUaBo?videoPreview=12020-01-01T12:00:00+00:003135.64Hong Kong Baptist UniversityNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/CkYuAGdP5aAoVjBKSBvQ6z https://cassyni.com/events/CJko2KYDifKjwDuCAA6cey/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Qz1wmdcuz4m5RFrZX48psg https://cassyni.com/events/CJko2KYDifKjwDuCAA6cey?videoPreview=1 Is it time to liberalise the news media?nohttps://cassyni.com/events/CJko2KYDifKjwDuCAA6cey?videoPreview=12021-05-22T12:00:00+00:00705.84Hong Kong Baptist UniversityAbstract not yet added.https://cassyni-user-files-prod.s3.amazonaws.com/Qz1wmdcuz4m5RFrZX48psg https://cassyni.com/slides/outline/Nfx9HEPwts4GGGATvuMYe1 https://cassyni.com/events/Nfx9HEPwts4GGGATvuMYe1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Kp725H6Tcq6DuwC9vZHgmC https://cassyni.com/events/Nfx9HEPwts4GGGATvuMYe1?videoPreview=1 Painting Demonstration-Copy of Zhao Mengfu’s Fishing Alone on an Autumn Rivernohttps://cassyni.com/events/Nfx9HEPwts4GGGATvuMYe1?videoPreview=12021-07-13T12:00:00+00:00442.04Hong Kong Baptist University“Copy of Zhao Mengfu’s Fishing Alone on an Autumn River” reflects characteristics of composition and brushwork applied by ancient masters. We invited contemporary ink artist Prof. Koon Wai-bong to recreate this painting. For this demonstration, he picked a type of linen paper with more ductile and thick texture, which dried quickly under the time constraint.https://cassyni-user-files-prod.s3.amazonaws.com/Kp725H6Tcq6DuwC9vZHgmC https://cassyni.com/slides/outline/PAbkKv3ULKcKG2hMXLeLuK https://cassyni.com/events/PAbkKv3ULKcKG2hMXLeLuK/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VG9KteMupToZeWm68kF4jp https://cassyni.com/events/PAbkKv3ULKcKG2hMXLeLuK?videoPreview=1 What we read now finding languagenohttps://cassyni.com/events/PAbkKv3ULKcKG2hMXLeLuK?videoPreview=12021-05-15T12:00:00+00:006519.32Hong Kong Baptist UniversityNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/VG9KteMupToZeWm68kF4jp https://cassyni.com/slides/outline/HjU6pPvhWHXEsAT7vReYus https://cassyni.com/events/HjU6pPvhWHXEsAT7vReYus/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HC3saBzGqqXJd7WkccEcZU https://cassyni.com/events/HjU6pPvhWHXEsAT7vReYus?videoPreview=1 Round table on Research in Interpreting: State of the Art and New Fields to Explorenohttps://cassyni.com/events/HjU6pPvhWHXEsAT7vReYus?videoPreview=12024-06-20T12:00:00+00:008496.16Hong Kong Baptist UniversityResearch in interpreting is getting increasingly interdisciplinary and very active in many of fields of investigation. On June 20th 2024 at The Department of Interpreting and Translation (DIT) of the University of Bologna at Forlì, we had the opportunity to take stock of the current and future trends during a round table with four leading interpreting scholars: Agnieszka Chmiel (Adam Mickiewicz University in Poznan- Head of Department of Translation Studies), Min-hua Liu (Hong Kong Baptist University · Centre for Translation), Alessandra Riccardi (University of Trieste - Department of Legal, Language, Interpreting and Translation Studies) and Elisabet Tiselius (Stockholm University - Institute for Interpreting and Translation Studies, Department of Swedish Language and Multilingualism. President of the European Society of Translation Studies, EST).https://cassyni-user-files-prod.s3.amazonaws.com/HC3saBzGqqXJd7WkccEcZU https://cassyni.com/slides/outline/YYvECuLSg28b7nAVSU7umw https://cassyni.com/events/YYvECuLSg28b7nAVSU7umw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/VG2H5isbMJU4dbQ2J68M18 https://cassyni.com/events/YYvECuLSg28b7nAVSU7umw?videoPreview=1 Between Publicity and Privacy: Social Media Platforms in the Post-Pandemic Hong Kong Independent Music Scenesnohttps://cassyni.com/events/YYvECuLSg28b7nAVSU7umw?videoPreview=12023-06-16T12:00:00+00:001005.04Hong Kong Baptist UniversityThis panel presents a multi-faceted and multi-disciplinary view on the Hong Kong indie music scene from 2019 onwards. Hong Kong society has undergone many social, cultural, economic and political changes since the protest movement of 2019 and has endured the COVID-19 pandemic and the restrictions imposed by the government. The indie music scene, having faced precarity in the past, has faced increasing precarity during this period due to pandemic restrictions and heightened scrutiny from the government on social gatherings. This panel addresses the ways that different communities and individuals in the scene have approached these challenges, and how the activities of the scene not only serve as means of survival, but how they have constituted new constructions and negotiations of identity in Hong Kong’s new cultural landscape.https://cassyni-user-files-prod.s3.amazonaws.com/VG2H5isbMJU4dbQ2J68M18 https://cassyni.com/slides/outline/TcSBk4sCHSbZigT9RzQv3o https://cassyni.com/events/TcSBk4sCHSbZigT9RzQv3o/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CbVAVcQ3E9Y82PtRNU7Zpz https://cassyni.com/events/TcSBk4sCHSbZigT9RzQv3o?videoPreview=1 Steam City — Book Talk with David Schleynohttps://cassyni.com/events/TcSBk4sCHSbZigT9RzQv3o?videoPreview=12021-02-18T12:00:00+00:004923.96Hong Kong Baptist UniversityAnyone interested in the rise of American corporate capitalism should look to the streets of Baltimore. There, in 1827, citizens launched a bold new venture: a “rail-road” that would link their city with the fertile Ohio River Valley. They dubbed this company the Baltimore & Ohio Railroad (B& O), and they conceived of it as a public undertaking—an urban improvement, albeit one that would stretch hundreds of miles beyond the city limits. Steam City tells the story of corporate capitalism starting from the street and moving outward, looking at how the rise of the railroad altered the fabric of everyday life in the United States. The B&O’s founders believed that their new line would remap American economic geography, but no one imagined that the railroad would also dramatically reshape the spaces of its terminal city. As railroad executives wrangled with city officials over their use of urban space, they formulated new ideas about the boundaries between public good and private profit. Ultimately, they reinvented the B&O as a private enterprise, unmoored to its home city. This bold reconception had implications not only for the people of Baltimore, but for the railroad industry as a whole. As David Schley shows here, privatizing the B&O helped set the stage for the rise of the corporation as a major force in the post-Civil War economy. Steam City examines how the birth and spread of the American railroad—which brought rapid communications, fossil fuels, and new modes of corporate organization to the city—changed how people worked, where they lived, even how they crossed the street. As Schley makes clear, we still live with the consequences of this spatial and economic order today.https://cassyni-user-files-prod.s3.amazonaws.com/CbVAVcQ3E9Y82PtRNU7Zpz https://cassyni.com/slides/outline/8M9cwQdjAazgx6QeWgpcMb https://cassyni.com/events/8M9cwQdjAazgx6QeWgpcMb/abstract https://cassyni-user-files-prod.s3.amazonaws.com/MSs6PgoREZMN4L4NQLJBp https://cassyni.com/events/8M9cwQdjAazgx6QeWgpcMb?videoPreview=1 The Singapore Story as Tragedynohttps://cassyni.com/events/8M9cwQdjAazgx6QeWgpcMb?videoPreview=12023-09-17T12:00:00+00:005769.48Hong Kong Baptist UniversityIn 2008, Kenneth Paul Tan anticipated the decay of meritocracy in Singapore’s technocratic political and public sector leadership, often credited then as a key factor in Singapore’s success story. What has emerged since is a crude form of elitism, lacking creativity, moral depth, and leadership to manage the contradictory dynamics of neoliberal globalization. In 2012, he anticipated the decay of more thoughtful and courageous strands of pragmatism in Singapore’s policymaking into a crude, unimaginative, and sometimes brutal form of market fundamentalism that — together with the rise of an entitled, insecure, and prickly ruling elite — would eventually create the conditions for widespread scepticism, popular resentment, and populist energies directed against the establishment and even authority in general. In a series of public lectures in 2019, he asked, “Are Singapore’s finest years coming to an end?” In this lecture for AcademiaSG, Tan revisits the underlying political and cultural criticisms that have motivated his writings over the decades, in order to explore the validity and desirability of explaining today’s (and possibly tomorrow’s) Singapore through the lens of “tragedy”. He also reflects on why critics like himself are often drawn to catastrophic thinking, what value that brings to the production of knowledge, and what price is paid for it.https://cassyni-user-files-prod.s3.amazonaws.com/MSs6PgoREZMN4L4NQLJBp https://cassyni.com/slides/outline/2v1yRtWxLYucZEAQumppN9 https://cassyni.com/events/2v1yRtWxLYucZEAQumppN9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/SDfa8eXoqbaLXovukiLVpa https://cassyni.com/events/2v1yRtWxLYucZEAQumppN9?videoPreview=1 Further Studies in Japannohttps://cassyni.com/events/2v1yRtWxLYucZEAQumppN9?videoPreview=12020-08-20T12:00:00+00:004266.72Hong Kong Baptist UniversityStudying art in Japan, particularly within Kyoto's historically rich environment, offers a distinctive pathway for artistic and personal growth. Academic programs, such as Master's degrees in mixed media (ceramics) and PhDs exploring concepts like scientific and artistic diagrams, emphasize independent research and production, with evaluation frequently based on exhibitions. Success in these programs necessitates a high level of Japanese language proficiency (N2 or above is recommended), alongside demanding academic writing requirements, which can include extensive weekly essays and substantial graduation theses (e.g., 140,000 words). Practical aspects for international students involve navigating competitive scholarships (e.g., MEXT, covering tuition and living costs), securing independent housing (with typical rents between 29,000–40,000 yen), and proactively managing visa applications. The immersive experience encourages profound self-reflection, independence, and the development of interpersonal skills for networking. Opportunities for artistic development include studio internships with established artists, participation in collaborative projects, and residency programs (e.g., Shigaraki) that foster connections with global peers and masters. While Kyoto's art market has traditionally focused on classical forms, governmental initiatives, such as relocating the Ministry for Culture and supporting new contemporary art institutions, are revitalizing the local art ecology. Graduates often leverage strong teacher connections and engage in art competitions (e.g., Osaka Creator Festival, Biwako Biennale) to build their careers, demonstrating how the Japanese art educational system serves as a gateway to the professional art world.https://cassyni-user-files-prod.s3.amazonaws.com/SDfa8eXoqbaLXovukiLVpa https://cassyni.com/slides/outline/3QfaUaAUn1TfYzhJWD7cdT https://cassyni.com/events/3QfaUaAUn1TfYzhJWD7cdT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Qmd6mQdVukuQnQEVhTLa4v https://cassyni.com/events/3QfaUaAUn1TfYzhJWD7cdT?videoPreview=1 China in Hollywood, Hollywood in China — A Discussion with Erich Schwartzel & Ying Zhunohttps://cassyni.com/events/3QfaUaAUn1TfYzhJWD7cdT?videoPreview=12022-12-06T12:00:00+00:004112.52Hong Kong Baptist UniversityIn the latest session of 'China Wise' book series, authors Erich Schwartzel and Ying Zhu of the books 'Red Carpet: Hollywood, China, and the Global Battle for Cultural Supremacy' and 'Hollywood in China: Behind the Scenes of the World’s Largest Movie Market,' respectively, discuss the relationship between China and Hollywood and how it affects U.S. interests. Asia Society’s Center on U.S.-China Relation’s Arthur Ross Director Orville Schell moderates the conversation.https://cassyni-user-files-prod.s3.amazonaws.com/Qmd6mQdVukuQnQEVhTLa4v https://cassyni.com/slides/outline/6PhjSVAxvYm6J9TQtXTGt5 https://cassyni.com/events/6PhjSVAxvYm6J9TQtXTGt5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2qmdiXMGqmh48oRTZzH7dG https://cassyni.com/events/6PhjSVAxvYm6J9TQtXTGt5?videoPreview=1 Cache Blocking Strategies Applied to Flux Reconstructionnohttps://cassyni.com/events/6PhjSVAxvYm6J9TQtXTGt5?videoPreview=12021-05-06T14:00:00+00:004025.08PyFROn modern hardware architectures, the performance of Flux Reconstruction (FR) methods for tensor product elements can be limited by memory bandwidth. In general, these methods are implemented as a chain of distinct kernels. Often, a dataset which has just been written to main memory by a kernel is read back immediately by the next kernel. The accepted solution for such a redundant expenditure of memory bandwidth is kernel fusion. However, on a practical level kernel fusion requires that the source for all kernels be available, thus preventing calls to certain third-party library functions. Moreover, it can add substantial complexity to a codebase. An alternative to full kernel fusion is using cache blocking strategies, which has become practically possible in recent years due to growth in the size of CPU L2 cache. In this approach, kernels remain distinct, and are executed one after another on small chunks of data that can fit in the cache, as opposed to on full datasets. These chunks of data stay in the cache and whenever a kernel requests access to data that is already in the cache, memory bandwidth is saved. In this talk, a variety of kernel grouping configurations will be presented for FR based Euler and Navier-Stokes solvers, alongside associated theoretical memory bandwidth savings, and actual achieved performance gains when implemented in the PyFR solver. Inviscid and viscous Taylor-Green Vortex test cases are used as benchmark for Euler and Navier-Stokes solvers, and the most performant strategies lead to a speedup of approximately 2.63x and 3.01x, respectively.https://cassyni-user-files-prod.s3.amazonaws.com/2qmdiXMGqmh48oRTZzH7dG https://cassyni.com/slides/outline/Hkj7xj7adXCwVP3nSXNRNM https://cassyni.com/events/Hkj7xj7adXCwVP3nSXNRNM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8ekchgE37SDC3jmt8Khvxv https://cassyni.com/events/Hkj7xj7adXCwVP3nSXNRNM?videoPreview=1 Bubbly Acoustic Metamaterialsnohttps://cassyni.com/events/Hkj7xj7adXCwVP3nSXNRNM?videoPreview=12021-06-08T14:00:00+00:005125.32MetaMATBubbly metamaterials are created by exploiting the low-frequency Minnaert resonance of bubbles, and can radically modify acoustic wave behaviour. In this presentation, I will first review the properties of bubble metascreens, which consist of a single layer of bubbles in a soft solid, and can be very efficient absorbers of waterborne acoustic waves. Two different metalayer configurations will be considered that allow almost perfect compensation of the radiative scattering losses, so that virtually all of the acoustic energy can be absorbed. I will show how optimization of bubble metascreens’ performance is facilitated by a relatively simple analytical model, and that, despite being resonance-based, near-perfect absorption is possible over a very wide frequency range even when the metalayer is ultrathin. In the second part of the talk, I will describe three-dimensional structures with pair-wise spatial correlations between the bubbles. Such structures exhibit doubly negative behaviour even though the low-frequency resonance of a single bubble is purely monopolar. Furthermore, this doubly negative behaviour can occur when the bubble pairs are arranged in either random or periodic configurations. Predictions for both types of structure will be presented and the influence of dissipation on doubly negative behaviour discussed. For the 3D crystalline metamaterial case, the focusing and imaging capabilities of a flat metalens will be demonstrated, showing the imaging of a point source by a slab with a relative refractive index n = -1, evidence of super-resolved focusing, and the imaging of an extended object.https://cassyni-user-files-prod.s3.amazonaws.com/8ekchgE37SDC3jmt8Khvxv https://cassyni.com/slides/outline/W6wE7pHhby3oP4HbQsw9WV https://cassyni.com/events/W6wE7pHhby3oP4HbQsw9WV/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LDvCzYCGPdBw4QkamYYuFU https://cassyni.com/events/W6wE7pHhby3oP4HbQsw9WV?videoPreview=1 Resonant States for Scattering Problems: Killing Mie Softlynohttps://cassyni.com/events/W6wE7pHhby3oP4HbQsw9WV?videoPreview=12021-01-19T14:00:00+00:003979.84MetaMATThis talk deals with issues common to those addressed by David Bergman, in that the topic is certain difficulties associated with complex resonant states encountered in scattering problems. These difficulties arise when one wishes to evaluate normalisation integrals and inner products for these states, which have rapid oscillations and diverging amplitudes at large dis- tances from the scatterer. Rather than using numerical treatments, the method presented here is analytic in nature, and relies on results of distri- bution theory. The method can yield closed form expressions for integrals over an infinite range involving the product of two Bessel functions of the same or different types, combined with a power of the radial distance. The essential point is that for rapidly oscillating functions with mean zero, the contribution to the integrals from the infinite upper limit is zero, despite the diverging amplitudes (equivocation trumps exaggeration).https://cassyni-user-files-prod.s3.amazonaws.com/LDvCzYCGPdBw4QkamYYuFU https://cassyni.com/slides/outline/YaBFMEXKoFpHjzm9xZqnER https://cassyni.com/events/YaBFMEXKoFpHjzm9xZqnER/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Eus6QJSiTsU2Nftbd9KX3c https://cassyni.com/events/YaBFMEXKoFpHjzm9xZqnER?videoPreview=1 Metamaterials, shear bands and invisibilitynohttps://cassyni.com/events/YaBFMEXKoFpHjzm9xZqnER?videoPreview=12020-07-07T14:00:00+00:004863.36MetaMATArchitected materials are preconized to yield extreme mechanical properties such as foldability, channeled response, and surface effects. These features are expected to lead to the production of artificial materials of unchallenged mechanical properties, in other words, metamaterials. Homogenization theory and Floquet-Bloch techniques will be applied to grids of elastic rods, subject to various conditions, including axial pre-stress, to demonstrate strain localization, wave channeling, total reflection, and negative refraction. Finally, invisibility through cloaking of voids in a flexurally vibrating plate will be presented.https://cassyni-user-files-prod.s3.amazonaws.com/Eus6QJSiTsU2Nftbd9KX3c https://cassyni.com/events/6tNxboLNmNEv7cSvgdaF4H/seminar/qa https://cassyni.com/slides/outline/6tNxboLNmNEv7cSvgdaF4H https://cassyni.com/events/6tNxboLNmNEv7cSvgdaF4H/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AUm4ppFBbivZz6hEAiRL4N https://cassyni.com/events/6tNxboLNmNEv7cSvgdaF4H?videoPreview=1 Random Batch Methods for Interacting Particles and Molecular Dynamicsnohttps://cassyni.com/events/6tNxboLNmNEv7cSvgdaF4H?videoPreview=12021-11-01T14:00:00+00:002990.44Journal of Computational PhysicsWe first develop random batch methods for classical interacting particle systems with large number of particles. These methods use small but random batches for particle interactions, thus the computational cost is reduced from $\mathcal{O}(N^2)$ per time step to $\mathcal{O}(N)$, for a system with $N$ particles with binary interactions. For one of the methods, we give a particle number independent error estimate under some special interactions. This method is also extended to molecular dynamics with Coulomb interactions, in the framework of Ewald summation. We will show its superior performance compared to the current state-of-the-art methods (for example PPPM) for the corresponding problems, in the computational efficiency and parallelizability. https://cassyni-user-files-prod.s3.amazonaws.com/AUm4ppFBbivZz6hEAiRL4N https://cassyni.com/slides/outline/MDHyQ9A9761MLmoyHraYp5 https://cassyni.com/events/MDHyQ9A9761MLmoyHraYp5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/yzxaSzTBkjpoBXeLTs6LE https://cassyni.com/events/MDHyQ9A9761MLmoyHraYp5?videoPreview=1 Topological Photonicsnohttps://cassyni.com/events/MDHyQ9A9761MLmoyHraYp5?videoPreview=12022-01-18T14:00:00+00:005033.6MetaMATI will present an overview on the field of Topological Photonics, with an emphasis on the Foundations, on Topological Insulator Lasers, and on current challenges.https://cassyni-user-files-prod.s3.amazonaws.com/yzxaSzTBkjpoBXeLTs6LE https://cassyni.com/slides/outline/8s5sF3z28eADPmzpptfSzH https://cassyni.com/events/8s5sF3z28eADPmzpptfSzH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6dRAabhUbJE5FTY8BfXX98 https://cassyni.com/events/8s5sF3z28eADPmzpptfSzH?videoPreview=1 Turbulence analysis in breaking wavesnohttps://cassyni.com/events/8s5sF3z28eADPmzpptfSzH?videoPreview=12022-04-12T10:40:00+00:001405.4Water WavesTwo different types of breaking waves, a spilling and a plunging one, are examined, while propagating in the surf zone along a sloped (1:20) impermeable and fixed bottom. They were reproduced in the laboratory wave channel of the DICATECh Department, that is 45 m long and 1 m wide, with the water depth close to the generator kept equal to 0.7 m. The main features of the waves are shown in Table 1, being H0 the wave height at the wave paddles, T the wave period, L0 the wavelength according to Airy theory and ξ0 the Irribarren number. The velocity field was measured by using a backscatter, two-component four-beam fibre-optic LDA system, and the free surface profile was assessed using resistance probes. Figures 1a and 1b show a part of the wave channel and the measuring system. Specifically, we analyze the power spectra of the turbulent longitudinal and vertical velocities (u’ and w’ respectively) assessed in selected vertical sections of the surf zone, at three different depths, i.e., close to the bottom, at mid-depth and near the surface (Figure 2a). In this way, we can detect some frequency regions where: i) the decrease in energy almost follows a slope -1, which is indicative of a coexisting energy production and cascade energy transfer (Nikora, 2005); ii) the spectrum shows peaks with a -3 slope, corresponding to quasi 2D large coherent structures (Truong et al., 2018); iii) the slope of the spectrum almost follows -5/3, thus is typical of the inertial subrange. Such information, examined along the longitudinal and vertical directions in the breaking zone, seems useful to describe the turbulent behavior of the waves. Furthermore, by considering the autocorrelation functions of the fluctuating velocities, the integral and turbulent length scales are also computed. As a second step, we use the Weakly-Compressible Smoothed Particle (WCSPH) model, coupled with a SubParticle Scale (SPS) approach to modeling turbulence, for reproducing numerically the waves. Preliminary comparisons of the above-mentioned spectra show a good agreement (Figure 2b). The Okubo–Weiss parameter W rated by W0=0.2σW, with σW being the standard deviation of W in the whole domain, allows to separate the flow into different regions, i.e., a vorticity-dominated region, a strain-dominated region, and a background field. Furthermore, the obtained numerical flow fields can therefore be used to investigate the characteristics of breaking vorticity within these flows. In Figures 3 and 4 snapshots of W/ W0 and vorticity ω are shown in the 2-D longitudinal section for the plunging case, during and after breaking. During breaking, due to the impact of the jet on the surface, positive vorticity is generated and propagates with the uprush flow, while negative vorticity spreads in the return flow at intermediate depths. After breaking (Figure 4b), positive vorticity largely persists at the surface in the wave bores, while negative vorticity rapidly decreases. The maps of W/W0 highlight the dominance of strain during breaking (Figure 3a); instead, after breaking (Figure 4a) some coherent structures seem to propagate obliquely towards the bottom.https://cassyni-user-files-prod.s3.amazonaws.com/6dRAabhUbJE5FTY8BfXX98 https://cassyni.com/slides/outline/5u8zjh56hAz8Pg58HRogBF https://cassyni.com/events/5u8zjh56hAz8Pg58HRogBF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5ZhbAQS1NKkXvLvD2cRunE https://cassyni.com/events/5u8zjh56hAz8Pg58HRogBF?videoPreview=1 Stability of time discretizations for semi-discrete high order schemes for time-dependent PDEsnohttps://cassyni.com/events/5u8zjh56hAz8Pg58HRogBF?videoPreview=12021-05-27T15:00:00+00:003774.32Partial Differential Equations and ApplicationsIn scientific and engineering computing, we encounter time-dependent partial differential equations (PDEs) frequently. When designing high order schemes for solving these time-dependent PDEs, we often first develop semi-discrete schemes paying attention only to spatial discretizations and leaving time $t$ continuous. It is then important to have a high order time discretization to main the stability properties of the semi-discrete schemes. In this talk we discuss several classes of high order time discretization, including the strong stability preserving (SSP) time discretization, which preserves strong stability from a stable spatial discretization with Euler forward, the implicit-explicit (IMEX) Runge-Kutta or multi-step time marching, which treats the more stiff term (e.g. diffusion term in a convection-diffusion equation) implicitly and the less stiff term (e.g. the convection term in such an equation) explicitly, for which strong stability can be proved under the condition that the time step is upper-bounded by a constant under suitable conditions, and the explicit Runge-Kutta methods, for which strong stability can be proved in many cases for semi-negative linear semi-discrete schemes. Numerical examples will be given to demonstrate the performance of these schemes.https://cassyni-user-files-prod.s3.amazonaws.com/5ZhbAQS1NKkXvLvD2cRunE https://cassyni.com/slides/outline/4uqneKn3pFsyivF8BTLMNM https://cassyni.com/events/4uqneKn3pFsyivF8BTLMNM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CoxGBR26qZ5ZezdoimpBm8 https://cassyni.com/events/4uqneKn3pFsyivF8BTLMNM?videoPreview=1 Children as Language Inquirers: Developing Language Awareness through Dual Language Picturebooksnohttps://cassyni.com/events/4uqneKn3pFsyivF8BTLMNM?videoPreview=12021-05-28T16:00:00+00:003725.28Linguistics and Applied Language StudiesChildren continuously engage in developing theories about how the world works as they inquire through play and interactions with others. In this presentation, Associate Professor Nicola Daly presents findings from a 6 week study with 8-11 year old children introducing them to dual language picturebooks featuring a range of languages. As Nicola and colleagues interacted with the children they observed and recorded their developing language awareness. Nicola and colleagues investigated children’s in-process thinking in the form of working theories about language as they engaged with dual language picturebooks in an afterschool club. Although dual language picturebooks are often associated with supporting bilingual learners, they argue that these books can also encourage children to develop their awareness of language and language diversity. Nicola and colleagues analysed field notes, audio recordings, and children’s artefacts to identify the kinds of working theories about language being explored by children and their strategies as learners in these inquiries. The findings show children developed working theories about what language is, what it means to know a language, and how language is learned.https://cassyni-user-files-prod.s3.amazonaws.com/CoxGBR26qZ5ZezdoimpBm8 https://cassyni.com/slides/outline/T91yj5tfZroSXS4J9z1pL5 https://cassyni.com/events/T91yj5tfZroSXS4J9z1pL5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CEWV9ZyZTFaxz5RwDXMUuC https://cassyni.com/events/T91yj5tfZroSXS4J9z1pL5?videoPreview=1 The Riemannian Quantitative Isoperimetric Inequalitynohttps://cassyni.com/events/T91yj5tfZroSXS4J9z1pL5?videoPreview=12021-11-04T14:00:00+00:003198.96Partial Differential Equations and ApplicationsThe (Euclidean) isoperimetric inequality says that any set has a larger perimeter than a ball with the same area. The quantitative isoperimetric inequality says that the difference in perimeters is bounded from below by the square of the distance from our set E to the ``closest" ball of the same area. In this talk, we will discuss an extension of this result to closed Riemannian manifolds with analytic metrics. In particular, we show that a similar inequality holds but with the distance raised to a power that depends on the geometry. We also have examples which show that a greater power than two is sometimes necessary and that the analyticity condition is necessary. This is joint work with O. Chodosh (Stanford) and L. Spolaor (UCSD).https://cassyni-user-files-prod.s3.amazonaws.com/CEWV9ZyZTFaxz5RwDXMUuC https://cassyni.com/slides/outline/Fn75fN1bUL4TFC59nza3KB https://cassyni.com/events/Fn75fN1bUL4TFC59nza3KB/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6oKbn7YpTy8pn2vDDZGxRU https://cassyni.com/events/Fn75fN1bUL4TFC59nza3KB?videoPreview=1 Long-time dynamics of the Fisher-KPP equation with nonlocal diffusion and free boundarynohttps://cassyni.com/events/Fn75fN1bUL4TFC59nza3KB?videoPreview=12020-09-28T15:00:00+00:003546.32Partial Differential Equations and ApplicationsWe consider the Fisher-KPP equation with free boundary and "nonlocal diffusion". We show the problem is well-posed, and its long-time dynamical behavior is governed by a spreading-vanishing dichotomy. Moreover, we completely determine the spreading profile, which may have a finite spreading speed determined by a semi-wave problem, or have infinite spreading speed (accelerated spreading), according to whether a threshold condition on the kernel function is satisfied. Further more, for some typical kernel functions, we obtain sharp estimates of the spreading speed (whether finite or infinite).https://cassyni-user-files-prod.s3.amazonaws.com/6oKbn7YpTy8pn2vDDZGxRU https://cassyni.com/events/NhDARZaq26jxtUm8T15R6V/abstract https://cassyni-user-files-prod.s3.amazonaws.com/LHMiGnCpXqgUSoPu7VEVhQ https://cassyni.com/slides/outline/GGfpNA7ThhqR9fTSQ6De21 https://cassyni.com/events/GGfpNA7ThhqR9fTSQ6De21/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AReiAffFLfG9vBEB12W2gE https://cassyni.com/events/GGfpNA7ThhqR9fTSQ6De21?videoPreview=1 State of the Art of Ceramic Total Hip Arthroplastynohttps://cassyni.com/events/GGfpNA7ThhqR9fTSQ6De21?videoPreview=12021-03-16T03:00:00+00:004050.24The Auckland Bioengineering InstituteFor centuries, mankind has been trying to find a way to restore the function of compromised limbs. Initially, only external devices were used to split and support. The dramatic advancements achieved in metallurgical, pharmacological, and surgical sciences during the 1950s allowed to safely replace damaged portions of the human body. At this time, which we could refer as the dawn of arthroplasty, several types of joint replacements were developed. The surgical pioneers had to face a number of obstacles during the development of medical devices designed for replacement of the human body. The novel biomaterials needed to be well integrated by the host with a minimal negative response. Examples for adverse tissue responses are bone resorption observed using polyethylene, and inflammatory reactions to metal debris with cobalt chrome alloys. Bioceramics were found to cause minimal tissue reactions, and thus showed excellent biocompatibility; Alumina ceramics in particular have offered a safe solution for bearing surfaces applications in arthroplasty surgery. However, the path to the development of ceramic biotechnology has been a long one. It took three decades to achieve the safety and quality of the current bioceramic composites, which consist of an alumina matrix with finely dispersed zirconia-reinforcing particles. The latest generation of this material, and the principal representative of this category, is the zirconia platelet-toughened alumina (ZPTA) composite. This novel bioceramic, used as a bearing couple for total hip arthroplasty, has shown excellent outcomes in the 20+ years of clinical use due to its high resistance to wear with minimal production of tribological debris, and minimal immune response, which are the prerequisites for long-term survival of joint replacement components. In this seminar, I will review the development history and analyse the current state-of-the-art of basic science and related clinical research of the contemporary ceramic total hip arthroplasty.https://cassyni-user-files-prod.s3.amazonaws.com/AReiAffFLfG9vBEB12W2gE https://cassyni.com/slides/outline/RATBeypTDPWmyxaFQQE9nM https://cassyni.com/events/RATBeypTDPWmyxaFQQE9nM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9WxKG4A1b4cKuTjiXBeDee https://cassyni.com/events/RATBeypTDPWmyxaFQQE9nM?videoPreview=1 Multitarget-Multisensor Information-driven Planning via Finite Set Statistics (FISST)nohttps://cassyni.com/events/RATBeypTDPWmyxaFQQE9nM?videoPreview=12021-03-17T14:00:00+00:002546.28Department of AeronauticsRecent work on information-driven sensor path planning has shown that the performance of mobile and remote sensors can be significantly improved by planning their motions based on probabilistic sensor models and the geometric characteristics of the sensor field-of-view (FOV). This talk discusses a general framework by which the expected information gain of future sensor measurements, positions, and orientations can be described by information theoretic functions in closed form, and, then, used to derive motion planning and control laws for active sensing and information gathering. Recent applications, such as underwater target detection and classification by active sonar and active scene perception by mobile cameras, have shown that the approach can greatly improve upon the quality of the sensor data, while decreasing the resources required, including time, computation, and energy consumption. This talk will present information-driven planning for space situational awareness (SSA), whereby information-driven sensor planning strategies are derived using finite set statistics (FISST). In this case, information-driven sensor planning seeks to optimize the information gain associated with tracking many moving targets by means of many space-based sensors. In addition to developing new FISST information gain functions, this talk will show how distributed optimal control (DOC) can be used to control large numbers of collaborative agents by providing solutions that scale up to hundreds of satellite-based sensors.https://cassyni-user-files-prod.s3.amazonaws.com/9WxKG4A1b4cKuTjiXBeDee https://cassyni.com/slides/outline/8NQe5jpcHpgPaK1K2nYUp5 https://cassyni.com/events/8NQe5jpcHpgPaK1K2nYUp5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CsfGhA1qMLK4F5Q8ufLyRx https://cassyni.com/events/8NQe5jpcHpgPaK1K2nYUp5?videoPreview=1 Climate change and the risk to financial stability; Reality or overreaction?nohttps://cassyni.com/events/8NQe5jpcHpgPaK1K2nYUp5?videoPreview=12021-11-25T22:00:00+00:005556.92SACLThe Reserve Bank of New Zealand has identified climate change as a significant risk to the New Zealand financial system, and placed the Reserve Bank at the centre of New Zealand’s climate change response. As the physical effects of climate change are slow-moving and relatively predictable over relevant time horizons, we should expect the financial systems to adapt to this changing world, and readily accommodate the impacts of climate events such as a slowly rising sea levels and the occasional stronger storms. The issue we address in this report is whether climate change is such an exception to this benign adaptation picture, that central banks and supervisors need to respond to the ‘challenge’ with some urgency. Or is this just a case of the Reserve Bank wanting to be seen to be ‘relevant’ and getting into the action in what is one of the biggest issues of our time? We have reviewed a large number of documents and despite the best efforts of many supervisors, none have been able to come up with convincing evidence that climate change represents a threat, let alone a systemic threat. A recent full-scale stress test for France found that the transition costs to a zero carbon economy would at most be four or five basis points and that it did not matter whether the transition was early or late. The physical risks from climate change were so slight that they could not be analysed. Papers: - The National climate change risk assessment, A case of science denial? [tailrisk.co.nz June 2021](http://www.tailrisk.co.nz/documents/NCCRAriskassessment.pdf) - Climate Change and the risk to Financial Stability [tailrisk.co.nz June 2021](http://www.tailrisk.co.nz/documents/ClimatechangeandFinancialStability.pdf) https://cassyni-user-files-prod.s3.amazonaws.com/CsfGhA1qMLK4F5Q8ufLyRx https://cassyni.com/slides/outline/3RvbcuMMuF9NBDHy2JqV5w https://cassyni.com/events/3RvbcuMMuF9NBDHy2JqV5w/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BbDgBMT7b1Ak56r1Q5BnWA https://cassyni.com/events/3RvbcuMMuF9NBDHy2JqV5w?videoPreview=1 Numerical Schemes for a Unified First Order Hyperbolic System of Continuum Mechanicsnohttps://cassyni.com/events/3RvbcuMMuF9NBDHy2JqV5w?videoPreview=12022-06-27T14:00:00+00:003529.84Journal of Computational PhysicsIn the first part of this talk we present the unified first order hyperbolic formulation of Newtonian continuum mechanics proposed by Godunov, Peshkov and Romenski (GPR). The governing PDE system can be derived from a variational principle and belongs to the class of symmetric hyperbolic and thermodynamically compatible systems (SHTC), which have been studied for the first time by Godunov in 1961 and later in a series of papers by Godunov & Romenski. An important feature of the model is that the propagation speeds of all physical processes, including dissipative processes, are finite. The GPR model is a geometric approach to continuum mechanics that is able to describe the behavior of nonlinear elasto-plastic solids at large deformations, as well as viscous Newtonian and non-Newtonian fluids within one and the same governing PDE system. This is achieved via appropriate relaxation source terms in the evolution equations for the distortion field and the thermal impulse. It can be shown that the GPR model reduces to the compressible Navier-Stokes equations in the stiff relaxation limit, i.e. when the relaxation times tend to zero. The unified system is also able to describe material failure, such as crack generation and fatigue. In the second part of the talk a family of high order ADER discontinuous Galerkin finite element schemes with a posteriori subcell finite volume limiter is introduced and applied to the GPR model. Computational results for nonlinear elasto-plastic solids with material failure are shown, as well as results in the fluid limit. In the absence of source terms, the homogeneous part of the GPR model is endowed with involutions, namely the distortion field A and the thermal impulse J need to remain curl-free. In the third part of the talk we therefore present a new structure-preserving scheme that is able to preserve the curl-free property of both fields exactly also on the discrete level. This is achieved via the definition of appropriate and compatible discrete gradient and curl operators on a judiciously chosen staggered grid. Furthermore, the pressure terms are discretized implicitly, in order to capture the low Mach number limit of the equations properly, while all other terms are discretized explicitly. In this manner, the resulting pressure system is symmetric and positive definite and can be solved with efficient iterative solvers like the conjugate gradient method. Last but not least, the new staggered semi-implicit scheme is asymptotic-preserving and thus also able to reproduce the stiff relaxation limit of the governing PDE system properly, recovering an appropriate discretization of the compressible Navier-Stokes equations. https://cassyni-user-files-prod.s3.amazonaws.com/BbDgBMT7b1Ak56r1Q5BnWA https://cassyni.com/slides/outline/DoYHbFwP7rmnhib73QnNmT https://cassyni.com/events/DoYHbFwP7rmnhib73QnNmT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/ESPaUqENUprvcpVzE6Z2NA https://cassyni.com/events/DoYHbFwP7rmnhib73QnNmT?videoPreview=1 Spectral/hp element methods for flow modelling using Nektar++nohttps://cassyni.com/events/DoYHbFwP7rmnhib73QnNmT?videoPreview=12022-05-10T15:00:00+00:003315.72Computer Physics CommunicationsNektar++ is an open-source framework that provides a flexible, high-performance and scalable platform for the development of solvers for partial differential equations using the high-order spectral/hp element method. In particular, Nektar++ aims to overcome the complex implementation challenges that are often associated with high-order methods, thereby allowing them to be more readily used in a wide range of application areas. In this presentation we will first provide some motivation behind the spectral/hp element method and the development of Nektar++. We will then provide some background on the code design and finally show some of the more challenging applications areas we have been tackling. The presentation will be given by three of the four team leaders of the project namely, Spencer Sherwin, Chris Cantwell and David Moxey. https://cassyni-user-files-prod.s3.amazonaws.com/ESPaUqENUprvcpVzE6Z2NA https://cassyni.com/events/LDzmJms6EAuCg1yyBt7E1B/seminar/qa https://cassyni.com/slides/outline/LDzmJms6EAuCg1yyBt7E1B https://cassyni.com/events/LDzmJms6EAuCg1yyBt7E1B/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2eKz4zmD3dK836H3oV2DDG https://cassyni.com/events/LDzmJms6EAuCg1yyBt7E1B?videoPreview=1 The anomalous magnetic moment of the muon in the Standard Modelnohttps://cassyni.com/events/LDzmJms6EAuCg1yyBt7E1B?videoPreview=12022-04-27T12:00:00+00:002808.64Physics ReportsPrecision measurements of low-energy observables can allow one to derive powerful constraints on physics beyond the Standard Model of particle physics---if the same quantity can be predicted at the same level of precision as experiment. The anomalous magnetic moment of the muon is a prominent example in which the sensitivity to potential contributions beyond the Standard Model crucially depends on the theoretical prediction. In the seminar I will give an overview of the first publication of the Muon g-2 Theory Initiative, Phys. Rept. 887 (2020) 1, which provided a comprehensive review of all sectors contributing to the Standard Model prediction, with focus on the hadronic corrections. https://cassyni-user-files-prod.s3.amazonaws.com/2eKz4zmD3dK836H3oV2DDG https://cassyni.com/slides/outline/CpF5VteLEwfe2xm6wSK3xZ https://cassyni.com/events/CpF5VteLEwfe2xm6wSK3xZ/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7FfDQizSu9r3kuCnkZVhcJ https://cassyni.com/slides/outline/6Pqr1dkPwMPj2qXGHCkpGM https://cassyni.com/events/6Pqr1dkPwMPj2qXGHCkpGM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/9GcrsU6QpWGLGvu3FCNbMQ https://cassyni.com/events/6Pqr1dkPwMPj2qXGHCkpGM?videoPreview=1 Some questions on order typesnohttps://cassyni.com/events/6Pqr1dkPwMPj2qXGHCkpGM?videoPreview=12022-04-12T18:25:00+00:001773.04Discrete & Computational GeometryNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/9GcrsU6QpWGLGvu3FCNbMQ https://cassyni.com/slides/outline/PgXzdZPmJNmqhiHXqYVBY1 https://cassyni.com/events/PgXzdZPmJNmqhiHXqYVBY1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DaxRHa6pBTViFF8twChDqY https://cassyni.com/events/PgXzdZPmJNmqhiHXqYVBY1?videoPreview=1 Tunability of electrically controlled piezoelectric phononic crystalsnohttps://cassyni.com/events/PgXzdZPmJNmqhiHXqYVBY1?videoPreview=12022-05-10T13:00:00+00:003449.08MetaMATPhononic Crystals (PCs) (i.e. periodic arrangements of several materials) have received a great deal of interest for the last two decades because of the unusual properties that they can exhibit. Classically, depending on material properties and geometrical arrangement, PCs can produce band gaps, i.e. frequency ranges where the propagation of waves is forbidden (i.e. waves are evanescent). These Bragg band gaps offer several potential applications such as sonic insulators or filters, from the kHz to the GHz range depending upon the spatial periodicity. In this presentation, the general case of PCs made of piezoelectric materials is studied where the band gaps may be tuned by changing the electrical boundary conditions. First, a stack of piezoelectric rods, poled along their thickness is considered [S. Degraeve et al, J. Appl. Phys. 115, 194508 (2014)]. This device exhibits Bragg gaps that depend on the electrical boundary conditions chosen on periodically placed electrodes. An analytical model is developed that is compared to finite element results, validating the model. Depending on the electrical boundary condition, tunability is clearly demonstrated, i.e. an increase or a decrease of the width and the position of the stop bands. Ultrasonic experiments are presented, showing a good agreement with the theoretical predictions. Then, more complex control involving space-time modulation of electrical boundary conditions give access to tuning/control of nonlinear physical effects such as non reciprocity [C. Croenne et al, Appl. Phys. Lett. 110(6), 061901 (2017)]. The second part of this presentation concerns the extension of this concept to surface acoustic waves (SAW). In fact, SAW devices are constituted of piezoelectric phononic crystals due to the periodicity of the metallization patterns. We have shown that their working frequencies can be modified by a change of the electrical conditions on the electrodes that constitute the mirrors of a single-port SAW resonator. Numerical as well as experimental results are presented that underline a shift of the resonance frequency by a change of the electrical condition. It allows the development of new strategies for tunable components, compatible with RF microfabrication.https://cassyni-user-files-prod.s3.amazonaws.com/DaxRHa6pBTViFF8twChDqY https://cassyni.com/slides/outline/GGovwJgtiWU3tMXHnmXBQH https://cassyni.com/events/GGovwJgtiWU3tMXHnmXBQH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/B5sNZ9nYWa3b3E27mgVxaS https://cassyni.com/events/GGovwJgtiWU3tMXHnmXBQH?videoPreview=1 Farewell to Suppression-Freedomnohttps://cassyni.com/events/GGovwJgtiWU3tMXHnmXBQH?videoPreview=12021-03-24T11:40:00+00:003246.64Logica UniversalisVal Plumwood and Richard Sylvan argued from their joint paper The Semantics of First Degree Entailment (Routley and Routley in Noûs 6(4):335–359, 1972, https://doi.org/10.2307/2214309) and onward that the variable sharing property is but a mere consequence of a good entailment relation, indeed they viewed it as a mere negative test of adequacy of such a relation, the property itself being a rather philosophically barren concept. Such a relation is rather to be analyzed as a sufficiency relation free of any form of premise suppression. Suppression of premises, therefore, gained center stage. Despite this, however, no serious attempt was ever made at analyzing the concept. This paper shows that their suggestions for how to understand it, either as the Anti-Suppression Principle or as the Joint Force Principle, turn out to yield properties strictly weaker than that of variable sharing. A suggestion for how to understand some of their use of the notion of suppression which clearly is not in line with these two mentioned principles is given, and their arguments to the effect that the Anderson and Belnap logics T, E and R are suppressive are shown to be both technically and philosophically wanting. Suppression-freedom, it is argued, cannot do the job Plumwood and Sylvan intended it to do.https://cassyni-user-files-prod.s3.amazonaws.com/B5sNZ9nYWa3b3E27mgVxaS https://cassyni.com/slides/outline/AqgHRna7tUNyVVH4BrXPQq https://cassyni.com/events/AqgHRna7tUNyVVH4BrXPQq/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BzCLVUPdnMNrwcyVyySaer https://cassyni.com/slides/outline/BLKtUUDeKvw2VFownHpBg9 https://cassyni.com/events/BLKtUUDeKvw2VFownHpBg9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/713SjKgj4MJCDcLtcLESSS https://cassyni.com/events/BLKtUUDeKvw2VFownHpBg9?videoPreview=1 Ersilia, a hub of open-source AI/ML models for drug discovery and global healthnohttps://cassyni.com/events/BLKtUUDeKvw2VFownHpBg9?videoPreview=12022-06-30T16:00:00+00:004316.56SisonkeBiotikThe Ersilia Open Source Initiative (EOSI) is a non-profit organisation whose mission is to strengthen the research capacity in LMIC. EOSI is focussed on disseminating and deploying artificial intelligence and machine learning (AI/ML) tools for drug discovery as a solution to minimise the cost and number of laboratory experiments. The main asset of EOSI is the Ersilia Model Hub, a free, online, open-source platform where scientists can browse through a catalogue of AI/ML models, select the ones that are relevant to their research and run online predictions without the need to write a single line of code. We gather, in a single resource, two classes of models. On the one hand, we collect models developed by third parties and available in scientific publications. On the other hand, we develop models in- house and/or in collaboration with research groups that operate in underserved settings. In this introductory talk, we will present our computational approach and infrastructure, with the goal of identifying potential collaborations and synergies between EOSI and Kenyatta University.https://cassyni-user-files-prod.s3.amazonaws.com/713SjKgj4MJCDcLtcLESSS https://cassyni.com/slides/outline/3vbpnDWmk4dBzgHUpQxTG9 https://cassyni.com/events/3vbpnDWmk4dBzgHUpQxTG9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/8VHE2S7FzoELcbCnwWLkFY https://cassyni.com/events/3vbpnDWmk4dBzgHUpQxTG9?videoPreview=1 Learning Languages through Cultural Activities: The ENACT Web Appnohttps://cassyni.com/events/3vbpnDWmk4dBzgHUpQxTG9?videoPreview=12022-10-28T03:00:00+00:002945.0Linguistics and Applied Language StudiesENACT is a free web app https://enacteuropa.com/ developed at Newcastle University, co-funded by the European Union. Released in February 2021, the app enables people to learn aspects of foreign languages while performing a meaningful real-world task which enables them to experience the culture of the foreign language. With the ENACT interactive player, users can learn a foreign language through the foreign culture by carrying out a cultural activity. Learn Italian while you’re making a Venetian carnival mask or Turkish while you’re making a shadow puppet! Devices will guide users through the stages of doing the activity through structured interactive content using photos, text, audio and video to help them. People can use the ENACT Author to create their own favourite cultural activity in their own language so that anyone else round the world can use it to learn the language and culture. ENACT has been used by over 11,000 people in 153 countries. In this presentation, I will provide an overview of the project aims, introduce the task-based language teaching and online interactive material design principles underlying the app design, and briefly demonstrate the key features of the ENACT app: the interactive player, the author, and the community. During the Q&A, we can explore opportunities for the Asia-Pacific region and I will update on a planned Māori project. https://cassyni-user-files-prod.s3.amazonaws.com/8VHE2S7FzoELcbCnwWLkFY https://cassyni.com/events/MhyCZTKYwuVBAEoV5xhWzH/seminar/qa https://cassyni.com/slides/outline/MhyCZTKYwuVBAEoV5xhWzH https://cassyni.com/events/MhyCZTKYwuVBAEoV5xhWzH/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Vqrx1RK4Tvp4znPqsLXWZk https://cassyni.com/events/MhyCZTKYwuVBAEoV5xhWzH?videoPreview=1 What is the 'opposite' of 'blue'? The language of colour spacesnohttps://cassyni.com/events/MhyCZTKYwuVBAEoV5xhWzH?videoPreview=12022-10-19T02:00:00+00:003444.56Computer Graphics GroupColour wheels are a tool for ordering and understanding hue. Different colour wheels differ in the spacing of the colours around the wheel. The opponent colour theory, Munsell’s colour system, the standard printer’s primaries, the artist’s primaries, and Newton’s rainbow all present different variations of the colour wheel. I show that some of this variation is owing to imprecise use of language, based on Berlin and Kay’s theory of basic colour names. I also show that the artist’s colour wheel is an outlier that does not match well to the technical colour wheels because its principal colours are so strongly connected to the basic colour names. This has implications for how we teach colour at tertiary level: students have had the artist's colour wheel embedded in their consciousness since early primary school; as educators we need to unpick that imprecise tool and instil more accurate concepts of colour. Understanding why the artist's colour wheel exists in its current form is important in helping students understand the more technically-correct colour spaces.https://cassyni-user-files-prod.s3.amazonaws.com/Vqrx1RK4Tvp4znPqsLXWZk https://cassyni.com/events/JFRyEfnsshcY8YVvSJKZTT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/BtEBGG6JigRWvPL2b2g2QW https://cassyni.com/slides/outline/XawHV8G3j4ZW1koWbXTt8D https://cassyni.com/events/XawHV8G3j4ZW1koWbXTt8D/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6cA9obEQ7Y38Yg2b9kjVGA https://cassyni.com/events/XawHV8G3j4ZW1koWbXTt8D?videoPreview=1 The Time dependent Vehicle Routing Problem with Time-Windows and Road-Network Informationnohttps://cassyni.com/events/XawHV8G3j4ZW1koWbXTt8D?videoPreview=12021-02-11T15:20:00+00:00712.04Operations Research ForumNo abstracthttps://cassyni-user-files-prod.s3.amazonaws.com/6cA9obEQ7Y38Yg2b9kjVGA https://cassyni.com/slides/outline/X513BUukm1Pya5DLHKd3VX https://cassyni.com/events/X513BUukm1Pya5DLHKd3VX/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KVpsT5umPz4qEtSg6QTar2 https://cassyni.com/events/X513BUukm1Pya5DLHKd3VX?videoPreview=1 Good or Gross?: Honey bee response to viruses in their foodnohttps://cassyni.com/events/X513BUukm1Pya5DLHKd3VX?videoPreview=12026-03-05T22:00:00+00:001797.44Royal Society PublishingPathogen detection plays a key role in enabling hosts to avoid infection. Many insects, including honey bees (<em>Apis mellifera</em>, L.), can detect pathogens indirectly, but it is unclear whether they can directly detect viruses outside of a host. We conducted cage and field choice assays using unadulterated and virus-spiked sucrose solutions to assess detection and behavioral responses of honey bees to virus-contaminated foods. In cage trials, nurse-aged bees generally preferred unadulterated sucrose solution in the summer, but showed a significant preference for virus-spiked solutions containing deformed wing virus (DWV), black queen cell virus, or chronic bee paralysis virus in the fall. In field trials, forager bees exhibited significantly higher feeding at, and consumption of, sucrose solutions with high concentrations of DWV compared to low DWV or virus-free controls in both the spring and fall. These findings demonstrate that honey bees can directly detect the presence of viruses in contaminated food sources, which has important implications for pathogen transmission within pollinator communities and disease management strategies aimed at improving honey bee health. However, the mechanisms underlying these phenomena remain unknown. Further research is needed to determine how virus presence alters honey bee behavior and impacts social immune function, foraging behaviors, and colony health.https://cassyni-user-files-prod.s3.amazonaws.com/KVpsT5umPz4qEtSg6QTar2 https://cassyni.com/slides/outline/5Q9vKTEwRPKJxeqMPEkWq3 https://cassyni.com/events/5Q9vKTEwRPKJxeqMPEkWq3/abstract https://cassyni-user-files-prod.s3.amazonaws.com/EyR694WpDXfUMGuN5CNDFC https://cassyni.com/events/5Q9vKTEwRPKJxeqMPEkWq3?videoPreview=1 The Principality of Hutt River (1970-2020) in Australia: Accounting for Sovereigntynohttps://cassyni.com/events/5Q9vKTEwRPKJxeqMPEkWq3?videoPreview=12022-12-05T22:00:00+00:005393.8SACLThis article broadens the perspective of accounting beyond examining its role in sovereign states to examining the role of accounting within the performance of micronationality. With an increasing trend toward post-nationalism, the status quo of sovereign states as sole providers of citizenship has been challenged by micronations. This article examines how a micronation (i.e., the Principality of Hutt River), exercised from the State of Western Australia, adopted the formal trappings of a sovereign state to uphold its independence from its host state (i.e., the Commonwealth of Australia) and how the host state responded through boundary work. Accounting was mobilised by the host state to deliver a coup de grâce to the micronation by constraining its financial resources through a legal battle over tax collection. A documentary and bibliographic research approach was adopted to examine the micronation’s adopted trappings of state and the host state’s boundary work in dismissing any potential legitimacy for the micronation towards sovereignty. The micronation’s formal trappings of a sovereign state and the host state’s reaction through boundary work, both including accounting technologies, illuminates the notions of the advent and operation of micronations, in competition with sovereign states and the roles of accounting in the advance of a post-national zeitgeist. Paper: click [here](https://web.tresorit.com/l/ppMwH#-qmA5FzktkFhn5pgifqreQ) (via [Tresorit](https://tresorit.com/)).https://cassyni-user-files-prod.s3.amazonaws.com/EyR694WpDXfUMGuN5CNDFC https://cassyni.com/slides/outline/Yabb4gFcqfiBwADBF5vQhj https://cassyni.com/events/Yabb4gFcqfiBwADBF5vQhj/abstract https://cassyni-user-files-prod.s3.amazonaws.com/WkEjuhNqu9GkyuPMUMJcDt https://cassyni.com/events/Yabb4gFcqfiBwADBF5vQhj?videoPreview=1 Decomposing a San Francisco estuary microbiome using long-read metagenomics reveals species- and strain-level dominance from picoeukaryotes to virusesnohttps://cassyni.com/events/Yabb4gFcqfiBwADBF5vQhj?videoPreview=12024-10-08T12:00:00+00:00690.0Microbiome Virtual International ForumAlthough long-read sequencing has enabled obtaining high-quality and complete genomes from metagenomes, many challenges still remain to completely decompose a metagenome into its constituent prokaryotic and viral genomes. This study focuses on decomposing an estuarine metagenome to obtain a more accurate estimate of microbial diversity. To achieve this, we developed a new bead-based DNA extraction method, a novel bin refinement method, and obtained 150 Gbp of Nanopore sequencing. We estimate that there are ~500 bacterial and archaeal species in our sample and obtained 68 high-quality bins (>90% complete, <5% contamination, ≤5 contigs, contig length of >100 kbp, and all ribosomal and tRNA genes). We also obtained many contigs of picoeukaryotes, environmental DNA of larger eukaryotes such as mammals, and complete mitochondrial and chloroplast genomes and detected ~40,000 viral populations. Our results suggest there are only a few strains that comprise most of the species abundances from viruses to picoeukaryotes, and to fully decompose a metagenome of this diversity requires 1 Tbp of long-read sequencing. We anticipate that as long-read sequencing technologies continue to improve, less sequencing will be needed.https://cassyni-user-files-prod.s3.amazonaws.com/WkEjuhNqu9GkyuPMUMJcDt https://cassyni.com/slides/outline/6QGBj5UgymHdDzyHZiqSjf https://cassyni.com/events/6QGBj5UgymHdDzyHZiqSjf/abstract https://cassyni-user-files-prod.s3.amazonaws.com/W6VovLb7SGe5s865GfRjHQ https://cassyni.com/events/6QGBj5UgymHdDzyHZiqSjf?videoPreview=1 Ileal transcriptome-correlated metabolic modelling reveals host-microbe interactionsnohttps://cassyni.com/events/6QGBj5UgymHdDzyHZiqSjf?videoPreview=12024-12-04T14:00:00+00:00660.0Microbiome Virtual International ForumSynthetic microbial communities provide defined microbiomes to study host-microbe interactions. Current analyses often link gene expression with microbial abundance but overlook the functional complexity of the microbiome. Metagenome-scale metabolic modeling (MSMM) integrates microbial metabolism with host transcriptomics, offering insights into metabolite-driven transcriptional changes. Using the oligoMM12 community, we examined microbial metabolites' influence on ileal transcription in C57BL/6 female mice. RNA-seq and qPCR quantified gene expression and microbial abundance, while MSMM predicted metabolite fluxes (pFlux). Correlations between pFlux and gene expression revealed associations between microbial metabolites and genes involved in nutrient transport, immune function, and transcriptional regulation. The findings suggest that microbial metabolites, such as short-chain fatty acids and dietary compounds, broadly influence host physiology, including gene expression and immune response. This integrated approach advances understanding of host-microbe interactions and provides a foundation for exploring personalized therapeutic and dietary strategies.https://cassyni-user-files-prod.s3.amazonaws.com/W6VovLb7SGe5s865GfRjHQ https://cassyni.com/events/Wc2nzaBQVCRXPgj8VW8kA1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Fxq6LSU1ieGwjneGRtr278 https://cassyni.com/events/Tn9GF1SbBkbpuFwZF8T1X/abstract https://cassyni-user-files-prod.s3.amazonaws.com/Nojk7b9HcvWqqsbTBYMi1C https://cassyni.com/slides/outline/3w2AVfF4nUX6BqjW6w35jT https://cassyni.com/events/3w2AVfF4nUX6BqjW6w35jT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/6UkFmEwDMyzRzbZeucWpsx https://cassyni.com/events/3w2AVfF4nUX6BqjW6w35jT?videoPreview=1 Local Network Leads: What They Do And Whynohttps://cassyni.com/events/3w2AVfF4nUX6BqjW6w35jT?videoPreview=12024-03-21T03:00:00+00:003506.52UKRNThis webinar was held on 21 March as part of Northumbria University Open Research Week 2024 and was an opportunity to learn more about the work of UKRN Local Network Leads (LNLs). There are 3 short presentations and discussions.https://cassyni-user-files-prod.s3.amazonaws.com/6UkFmEwDMyzRzbZeucWpsx https://cassyni.com/slides/outline/SeUs8vJgjqxJ7GjAjysTN5 https://cassyni.com/events/SeUs8vJgjqxJ7GjAjysTN5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/FyMmgexYs7yb9kXctVP9WW https://cassyni.com/events/SeUs8vJgjqxJ7GjAjysTN5?videoPreview=1 Examples from Brazil, India and South Africa of the challenges and difficulties encountered in implementing ABSnohttps://cassyni.com/events/SeUs8vJgjqxJ7GjAjysTN5?videoPreview=12025-05-05T10:00:00+00:00783.32Microbiome Virtual International ForumRestrictions placed on the distribution of biological material by the legislation of countries such as India, South Africa, or Brazil exclude strains that could serve as type material for the validation or valid publication of prokaryotic species names. This problem goes beyond prokaryotic taxonomy and is also relevant for other areas of biological research.https://cassyni-user-files-prod.s3.amazonaws.com/FyMmgexYs7yb9kXctVP9WW https://cassyni.com/slides/outline/5R2DryDQua2qVm1eCgTYdT https://cassyni.com/events/5R2DryDQua2qVm1eCgTYdT/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DjYbr9B7R7rpi3iSjpSBV8 https://cassyni.com/events/5R2DryDQua2qVm1eCgTYdT?videoPreview=1 Varying Newton Gravitational “Constant” Cosmologynohttps://cassyni.com/events/5R2DryDQua2qVm1eCgTYdT?videoPreview=12025-03-29T00:00:00+00:00827.24Annals of PhysicsWe demonstrate that quantum random fluctuations of Newton's "constant", $G$, are required to allow the vacuum to radiate Hawking radiation when it is disturbed by a mass, whether it be a black hole or not. We deduce, from Heisenberg uncertainty principle, the maximum quantum fluctuation amplitude of an energy-dependent Newton gravitational "constant" $G$. This allows us to deduce a cosmic law for the variation of $G$ as a function of the cosmological redshift. Consequences for the Friedman-Lema\^{i}tre-Robertson-Walker (FLRW) Model of the Universe are explored and the physical nature of the Dark Matter (DM) components of the cosmological fluid is revealed. It is also argued that oscillations of $G$ in black holes are a new physical mechanism for the emission of Gravitational Waves (GWs). Thus, conversion of part of the black hole rest mass into GW energy, through this mechanism, should occur in all black holes present in Active Galactic Nuclei (AGN) accounting for their luminosity and for the Stochastic Gravitational Wave Background (SGWB) recently detected by Timing Pulsar Array (TPA) teams. The presented data analysis obtains the result that fluctuations of Newton "constant" $G$ allow for explaining several Cosmology experimental results, such as: Hubble Tension, DM density, and fire wall paradox.https://cassyni-user-files-prod.s3.amazonaws.com/DjYbr9B7R7rpi3iSjpSBV8 https://cassyni.com/slides/outline/7tGF6PT36roKrhVCkNNBMP https://cassyni.com/events/7tGF6PT36roKrhVCkNNBMP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/5uicKBqRhT2iN9gngQ6DGr https://cassyni.com/events/7tGF6PT36roKrhVCkNNBMP?videoPreview=1 Efficacy of goserelin in ovarian function suppression and preservation for pre- and peri-menopausal breast cancer patients: a systematic reviewnohttps://cassyni.com/events/7tGF6PT36roKrhVCkNNBMP?videoPreview=12025-04-11T05:00:00+00:00375.72Sage PublishingBackground: Over the past few decades, the gonadotropin-releasing hormone agonist goserelin has been evaluated in ovarian function suppression (OFS) with adjuvant endocrine therapy and ovarian function preservation (OFP) during chemotherapy. Objective: The goal of this systematic literature review was to assess the efficacy of goserelin in OFS and OFP in combination with endocrine therapies and chemotherapy, respectively, in pre- and perimenopausal women with early-stage breast cancer. Design: This study is a systematic review. Data sources and methods: The literature search was conducted using PubMed. Prospective clinical studies evaluating the efficacy of goserelin in OFS or OFP in pre- or perimenopausal breast cancer were identified by four reviewers working in teams of two. Results: Twenty-nine studies were included in this systematic review. The addition of goserelin as OFS to adjuvant endocrine therapy generally resulted in significant benefits in disease-free survival. Studies have shown better OFP results among women 40 years or younger compared with older patients. Chemotherapy in association with goserelin for OFP resulted in a higher recovery rate of menses within 6–24 months, a shorter time for menstrual recovery, and significantly higher pregnancy rates when compared with cytotoxic therapy without goserelin. Hormonal recovery with higher anti-Müllerian hormone and estradiol levels, and lower follicle-stimulating hormone and luteinizing hormone levels occurred more frequently among women who received goserelin during chemotherapy as compared with those receiving cytotoxic therapy alone. The benefits of goserelin in OFP were more substantial among women 40 years or younger than in older patients. Conclusion: The findings of this systematic review highlight the benefits of adding goserelin to endocrine therapies for OFS and chemotherapy for OFP in early-stage breast cancer. Additionally, scientific data supporting OFS (including goserelin) in combination with newer agents such as cyclin-dependent kinase 4 and 6 inhibitors and bone-modifying agents are emerging.https://cassyni-user-files-prod.s3.amazonaws.com/5uicKBqRhT2iN9gngQ6DGr https://cassyni.com/events/2wPV2jmP5EJDm3xqcJh87w/seminar/qa https://cassyni.com/slides/outline/2wPV2jmP5EJDm3xqcJh87w https://cassyni.com/events/2wPV2jmP5EJDm3xqcJh87w/abstract https://cassyni-user-files-prod.s3.amazonaws.com/CK2Tq3pjbrjz1MEtc8Pk3Y https://cassyni.com/events/2wPV2jmP5EJDm3xqcJh87w?videoPreview=1 Electro-microbial pathways for sustainable bioremediationnohttps://cassyni.com/events/2wPV2jmP5EJDm3xqcJh87w?videoPreview=12025-09-29T10:00:00+00:003215.8ElsevierClimate change and the depletion of resources demand technologies that address pollution while advancing sustainability. This talk will present electron-driven microbial reactions as the basis for microbial electrochemical technologies (METs), offering new strategies for resilient bioremediation and resource recovery. Environmental pollutants often persist due to limitations in electron donors or acceptors, constraining biodegradation. METs overcome this challenge by enhancing electron flow with minimal energy inputs and reduced chemical additives. Evidence from laboratory and pilot-scale studies will be discussed, demonstrating the potential of in situ applications for the remediation of contaminated water, a persistent global health concern. This talk will highlight how bridging fundamental electromicrobiology with innovation can deliver sustainable solutions for pollution control and resource recovery.https://cassyni-user-files-prod.s3.amazonaws.com/CK2Tq3pjbrjz1MEtc8Pk3Y https://cassyni.com/slides/outline/GmbeZ8urAmenHRiZmJnaso https://cassyni.com/events/GmbeZ8urAmenHRiZmJnaso/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HTM4ZuiaorVMYPcAQ1aKHp https://cassyni.com/events/GmbeZ8urAmenHRiZmJnaso?videoPreview=1 Selection of Donors for Hematopoietic Cell Transplantation: Donor age is becoming more and more importantnohttps://cassyni.com/events/GmbeZ8urAmenHRiZmJnaso?videoPreview=12025-08-04T11:43:47+00:00758.44LeukemiaThe results of allogeneic hematopoietic cell transplantation (alloHCT) may be influenced by smart donor selection. Today, insights from registry studies and translational science can be used to select an optimal donor. In recent work, we investigated whether young unrelated donors (UD) provide a benefit for older patients with myeloid malignancies compared to HLA-identical sibling donors (MSD). In total, we analyzed data from 3460 patients. With multivariable adjustment event-free survival (EFS) (HR 0.86, p = 0.003), overall survival (HR 0.82, p < 0.001), and risk of relapse (HR 0.84, p = 0.018) were significantly better for HLA-compatible UD compared to MSD. No survival advantage was found for UD with unfavorable sex or CMV constellation. In a meta-analysis on 9905 patients with myeloid malignancies, including ours, we found reduced risk of relapse (pooled HR 0.78, p = 0.006) and better EFS (pooled HR 0.89, p < 0.001) for young matched UD versus MSD. In this seminar, we will review our results and interpret their impact in the context of current literature on donor selection for HLA-matched alloHCT.https://cassyni-user-files-prod.s3.amazonaws.com/HTM4ZuiaorVMYPcAQ1aKHp https://cassyni.com/events/8MTUCLJUbZBgZM54ew9UJR/seminar/qa https://cassyni.com/slides/outline/8MTUCLJUbZBgZM54ew9UJR https://cassyni.com/events/8MTUCLJUbZBgZM54ew9UJR/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NppNLaHD8h5UsKTRyJqgog https://cassyni.com/events/8MTUCLJUbZBgZM54ew9UJR?videoPreview=1 Faster and objective Level Set-DEM mechanical simulations of discrete systems with convex particles from contact history and particle surface considerationsnohttps://cassyni.com/events/8MTUCLJUbZBgZM54ew9UJR?videoPreview=12025-10-02T12:05:00+00:001795.44Computer Physics CommunicationsAiming for versatile simulations of the mechanics of discrete systems with arbitrary convex particles, an extended Level Set (LS) description of particle shape is proposed in the framework of the Discrete Element Method (DEM) and of the YADE open-source code. The LS shape description as a discrete field of the signed distance function is first proposed to directly output particle surface in a validated workflow. It mostly includes an innovative optimization for the surface nodes discretization which combines with the LS distance field for DEM contact treatment. In their optimized definition, surface nodes locate in a nearly uniform fashion over a particle and are handled in a sparse manner during contact treatment, thanks to an original consideration of contact history. As such, computation speed gains are reported with a factor of more than 3 during simulations of quasi-static mechanical loading. The proposed nodes definition is also shown to be instrumental to insure objectivity of the LS contact model and DEM simulations.https://cassyni-user-files-prod.s3.amazonaws.com/NppNLaHD8h5UsKTRyJqgog https://cassyni.com/slides/outline/6sZuHYPg5uNqqeANfJ67A5 https://cassyni.com/events/6sZuHYPg5uNqqeANfJ67A5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/UKqBJv47XxgpGsBDriqEYN https://cassyni.com/events/6sZuHYPg5uNqqeANfJ67A5?videoPreview=1 The Impact of Excessive Caesarean Deliveries on Gestational Age at Birth in Mexico: National-Level Trends, 2010–2023.nohttps://cassyni.com/events/6sZuHYPg5uNqqeANfJ67A5?videoPreview=12025-11-29T06:00:00+00:001827.88Women's HealthBackground: C-section rates in Mexico have risen dramatically over the past decade, reaching 55% by 2023. While life-saving when correctly indicated, excessive use may alter the natural timing of childbirth and shift population-level birth outcomes. Objectives: To examine national trends in gestational age, birth weight, and birth length from 2010 to 2023, and evaluate their association with mode of delivery. Design: Population-based repeated cross-sectional analysis using national birth certificate data. Methods: We analysed a 1-in-1,000 random sample of birth certificates from Mexico’s national registry (n = 27,435) for 2010–2023. Fractional polynomial models assessed national trends in birth outcomes by delivery type. Multivariable linear regressions adjusted for maternal age, parity, schooling and year of birth. Marginal effects were used to examine changes in C-section rates by maternal age. Results: The C-section rate rose from 45% in 2010 to 55% in 2023. Over the same period, full-term births (≥39 weeks) declined from 66.5% to 57.7%, while early-term births (37–38 weeks) rose from 26.6% to 34.2%. Gestational age declined over time for both vaginal and C-section deliveries. A sharp rise in C-section rates beginning around 2015 coincided with abrupt downward trends in gestational age, birth weight, and length across delivery modes. In adjusted models, birth by C-section was associated with a reduction of 0.5 weeks in gestational age at birth (p < 0.001), increased risk of prematurity (β = 0.053, p < 0.001), and reductions in birth weight (β = –21.04 g, p = 0.001) and length (β = –0.41 cm, p < 0.001), compared to vaginal delivery. Conclusion: The rising prevalence of C-sections in Mexico aligns with a broader shift toward earlier deliveries, driven primarily by an increase in early-term births. This shift affects both surgical and spontaneous deliveries and may have long-term implications for children https://cassyni-user-files-prod.s3.amazonaws.com/UKqBJv47XxgpGsBDriqEYN https://cassyni.com/slides/outline/EHHxyo6YfmggLDgqdAwqa5 https://cassyni.com/events/EHHxyo6YfmggLDgqdAwqa5/abstract https://cassyni-user-files-prod.s3.amazonaws.com/7RZw9mGyrA4rPWcpDp23xA https://cassyni.com/events/EHHxyo6YfmggLDgqdAwqa5?videoPreview=1 The state-space structure around spiral defect chaos in Rayleigh-Bénard convectionnohttps://cassyni.com/events/EHHxyo6YfmggLDgqdAwqa5?videoPreview=12025-12-11T10:45:12+00:00902.88Royal Society PublishingThe co-existence of ideal straight rolls (ISRs) and spiral-defect chaos (SDC) as bistable states in Rayleigh-Bénard convection above the onset of the linear instability is well established in extended spatial domains ($$\Gamma \leq 80$$, where $$\Gamma$$ is the aspect ratio of the domain). However, multiple stable states have also been found independently, raising questions about the precise understanding of this observed bistability in extended domains. In this study, we isolate the localised structures of SDC by gradually reducing the spatial domain. By minimising the domain systematically to $$\Gamma = 4\pi$$, SDC appears transiently and eventually stabilises into new stable states referred to as elementary states. These elementary states are visibly and statistically similar to the spatially local patterns of SDC, indicative of invariant solutions underpinning the pattern formation in SDC. To understand the state space structure further, we have examined the edge between ISRs and the elementary states, revealing multiple edge states, and conducted a series of numerical simulations along the unstable manifolds of unstable ISRs. The unstable ISRs near the Busse balloon are connected to stable ISRs and the base state through networks of heteroclinic orbits, forming a basin of attraction for each stable ISR. In contrast, the unstable ISRs further from the Busse balloon contain some unstable manifolds, along which the solution trajectory leads to SDC, suggesting that these unstable ISRs sit on the boundary between stable ISRs and SDC. Finally, we propose a state space structure around the basic heat conduction state, stable/unstable ISRs, elementary states and transient SDChttps://cassyni-user-files-prod.s3.amazonaws.com/7RZw9mGyrA4rPWcpDp23xA https://cassyni.com/events/GkXzDDLAs4TAhAAQArrUJ1/abstract https://cassyni-user-files-prod.s3.amazonaws.com/B7jm6Yq6u6KvVc2XwxhNYv https://cassyni.com/slides/outline/9LovWxdJHC9ew7yVchEqqw https://cassyni.com/events/9LovWxdJHC9ew7yVchEqqw/abstract https://cassyni-user-files-prod.s3.amazonaws.com/NZTnHrDpraMrwayF5Hc7Ur https://cassyni.com/events/9LovWxdJHC9ew7yVchEqqw?videoPreview=1 Quantum Algorithm for Testing Graph Completenessnohttps://cassyni.com/events/9LovWxdJHC9ew7yVchEqqw?videoPreview=12025-12-17T21:00:00+00:001921.04Annals of PhysicsTesting graph completeness is a critical problem in computer science and network theory. Leveraging quantum computation, we present an efficient algorithm using the Szegedy quantum walk and quantum phase estimation (QPE). Our algorithm, which takes the number of nodes and the adjacency matrix as input, constructs a quantum walk operator and applies QPE to estimate its eigenvalues. These eigenvalues reveal the graph’s structural properties, enabling us to determine its completeness. We establish a relationship between the number of nodes in a complete graph and the number of marked nodes, optimizing the success probability and running time. In our hypotheses, the time complexity of the algorithm is O(log^2(n)), where n is the number of nodes of the graph, offering a clear quantum advantage over classical methods. This approach can be useful in network structure analysis, evaluating classical routing algorithms, and assessing systems based on pairwise comparisons.https://cassyni-user-files-prod.s3.amazonaws.com/NZTnHrDpraMrwayF5Hc7Ur https://cassyni.com/slides/outline/8qpr6io91QUWmZQAJnwaXo https://cassyni.com/events/8qpr6io91QUWmZQAJnwaXo/abstract https://cassyni-user-files-prod.s3.amazonaws.com/KwDA1Dp9z3tXN1R8BDwC4v https://cassyni.com/events/8qpr6io91QUWmZQAJnwaXo?videoPreview=1 Diabetes alters the supragingival microbiome through plasma-to-saliva migration of glucose and fructosenohttps://cassyni.com/events/8qpr6io91QUWmZQAJnwaXo?videoPreview=12026-02-10T00:30:00+00:00391.48Microbiome Virtual International ForumDental caries, a dysbiotic biofilm disease driven by polymicrobial acidogenesis, often coexists with type 2 diabetes (T2D). Previous studies suggest covarying relationships between circulating and salivary metabolites in patients with T2D. However, the role of hyperglycemia-induced saccharide migration from plasma to saliva in caries pathogenesis remains unclear. Here, we developed a novel method for untargeted metabolomics profiling of trace saliva from sublingual and submandibular glands, comparing this profile with those of plasma and whole saliva in participants with T2D (n = 31) and those with normoglycemia (n = 30). This comparison aimed to determine how circulating saccharide migration into the oral cavity and its subsequent microbial consumption are linked to dental caries. Additionally, shotgun metagenomic sequencing was combined with this analysis to investigate the cariogenic impact of circulating saccharide migration on the composition and function of supragingival biofilm using MetaPhlAn4 and HUMAnN3 pipelines. The metabolomics profiles of glandular saliva showed intermediate dissimilarity between plasma and whole saliva, reflecting cardiometabolic traits more sensitively than whole saliva. Glucose and fructose showed a decreasing positive correlation with glycemic parameters in the order of plasma, glandular saliva, and whole saliva, suggesting systemic-to-oral migration and subsequent microbial consumption. Saccharide migration was more pronounced in participants with dental caries and plaque accumulation, coinciding with shifts in supragingival microbiota, including depletion of *Streptococcus sanguinis*, *Corynebacterium durum*, and *Rothia aeria*, and enrichment of *Streptococcus mutans*, *Veillonella parvula*, and *Actinomyces* sp. *oral taxon 448*. Glycolytic potential increased at the community level. Improved glycemic control reduced fructose migration and mitigated dysbiosis, decreasing fructose phosphotransferase abundance and shifting the *S. mutans*–*S. sanguinis* balance. Experimental validation demonstrated that fructose promotes *S. mutans* dominance over *S. sanguinis* in dual-species biofilms. This study establishes saccharide migration as a metabolic driver of supragingival dysbiosis in T2D. The findings highlight the role of both glucose and fructose in caries pathogenesis and suggest that glycemic control may be an effective strategy as part of caries control.https://cassyni-user-files-prod.s3.amazonaws.com/KwDA1Dp9z3tXN1R8BDwC4v https://cassyni.com/events/LCjkASgD6wDW3oPJfnPMYh/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PN1JfmLZdL9MVW7RibhesQ https://cassyni.com/events/LCjkASgD6wDW3oPJfnPMYh?videoPreview=1 Diapausing bumble bee queens avoid drowning by using underwater respiration, anaerobic metabolism, and profound metabolic depression.nohttps://cassyni.com/events/LCjkASgD6wDW3oPJfnPMYh?videoPreview=12026-02-27T17:46:07+00:001846.28Royal Society PublishingOverwintering bumble bee queens enter a state of diapause, remaining buried underground until spring. Remarkably, queens of the common eastern bumble bee (Bombus impatiens) can survive complete submersion for at least one week. We investigated the physiological mechanisms enabling this tolerance, testing the hypothesis that submerged diapausing queens rely on both underwater respiration and anaerobic metabolism for survival. Using respirometry, we detected low but consistent CO2 production during submersion, persisting through four and eight days underwater. Underwater gas exchange, measured from CO2 levels in the headspace of a respirometry chamber, was supported by a decline in dissolved oxygen in the water. Submerged bees also accumulated lactate as an anaerobic end-product during submersion, which decreased to pre-submersion levels after a week of recovery. Recovery was characterized by an immediate increase in metabolic rate, followed by a gradual decline to pre-submersion levels over one week, accompanied by changes in respiratory patterns. This study reveals that diapausing bumble bee queens survive and recover from prolonged flooding through a combination of underwater respiration and anaerobic metabolism in a state of profound metabolic depression. Such physiological capacity underpins their resilience to environmental extremes and provides insights into how terrestrial insects may persist in flood-prone habitats.https://cassyni-user-files-prod.s3.amazonaws.com/PN1JfmLZdL9MVW7RibhesQ https://cassyni.com/slides/outline/5t26AWTeajw4W9YKA1PM73 https://cassyni.com/events/5t26AWTeajw4W9YKA1PM73/abstract https://cassyni-user-files-prod.s3.amazonaws.com/HJesJwPzZzzgfEFXDsL8E https://cassyni.com/events/5t26AWTeajw4W9YKA1PM73?videoPreview=1 Daily sampling reveals rapid microbiota alterations and antimicrobial resistance gene acquisition during intercontinental travelnohttps://cassyni.com/events/5t26AWTeajw4W9YKA1PM73?videoPreview=12026-05-12T14:00:00+00:00631.2Microbiome Virtual International ForumWith increasing global travel, individuals are frequently exposed to new diets, environments, and microbial communities that may influence gut microbiota dynamics and facilitate the acquisition of antimicrobial resistance genes (ARGs). At present, studies characterising day-to-day microbiota and ARGs dynamics during travel are lacking. This study aimed to elucidate the short-term effects of travel on gut microbiota dynamics and ARG acquisition using a high-frequency sampling approach. A cohort of eleven Dutch travellers to Asia self-collected 254 fecal swabs before, during, and after travel for microbiota and resistome profiling. Samples were analysed using qPCR targeting clinically relevant ARGs (qnrB, qnrS and blaCTX-M) and profiled by 16S rRNA gene amplicon sequencing. Longitudinal analyses revealed pronounced inter- and intra-individual variation, with rapid shifts in microbiota composition observed within the first days of travel. An increase in Enterobacterales and a decline in commensal taxa were detected during early travel, coinciding with swift ARG acquisition. These findings underscore the key role of travel in global ARG dissemination.https://cassyni-user-files-prod.s3.amazonaws.com/HJesJwPzZzzgfEFXDsL8E https://cassyni.com/events/Vb7UGgzxFMb8r4ioKqxM81/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GYKy97xq3mDbFNp76bbWm4 https://cassyni.com/events/4QdjK3poKaoM5emPJ1u19o/abstract https://cassyni-user-files-prod.s3.amazonaws.com/2vM8oTwcDxWpfXG6piVMWn https://cassyni.com/events/Ng6FrNyNufgtzxEKKaf62H/abstract https://cassyni-user-files-prod.s3.amazonaws.com/ENpcs1c2X7JTBPY1hAD8fQ https://cassyni.com/events/DnRP25Kw1RiipC4HuzN3hF/abstract https://cassyni-user-files-prod.s3.amazonaws.com/PNzKuRKXz2R2hGd8cmndUA https://cassyni.com/events/EH8EJ21EFc8KTMWRumKBnM/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GEKAZMkD3dYKrEeLd2uYFg https://cassyni.com/events/S9AKM8HtdjAktQ3fg7HfrD/seminar/qa https://cassyni.com/events/S9AKM8HtdjAktQ3fg7HfrD/abstract https://cassyni-user-files-prod.s3.amazonaws.com/78FRzBfjn8iyFEgFKS75QS https://cassyni.com/events/S9AKM8HtdjAktQ3fg7HfrD?videoPreview=1 Postgraduate Research Colloquium 2026 - Urban Transformation: Planning, Policy and Developmentnohttps://cassyni.com/events/S9AKM8HtdjAktQ3fg7HfrD?videoPreview=12026-09-22T23:00:00+00:00637.04Business SchoolThe University of Auckland and Keio Economic Observatory (KEO) co-organise the Postgraduate Research Colloquium 2026 - Urban Transformation: Planning, Policy and Development, which is a hybrid academic research exchange bringing together postgraduate researchers, academics, and urban practitioners to examine contemporary processes of urban transformation in New Zealand and Japan. Held on 23 September 2026 at the University of Auckland Business School, the colloquium features opening perspectives from New Zealand and Japan, followed by five postgraduate research presentations, and a moderated roundtable discussion session. The event provides Master’s and PhD researchers with an opportunity to present emerging empirical research and develop connections with researchers across institutions and countries. Held in the lead-up to World Habitat Day 2026 (https://urbanoctober.unhabitat.org/postgraduate-research-colloquium-2026-urban-transformation-planning-policy-and-development), the colloquium contributes an academic research perspective to the global discussion on “Adequate Housing for All”, with particular attention given to the relationship between urban transformation and housing affordability. RSVP: Register at https://forms.gle/mgqXWTnSxPRW48U86 for the zoom link. https://cassyni-user-files-prod.s3.amazonaws.com/78FRzBfjn8iyFEgFKS75QS https://cassyni.com/events/FGu2L64LyeypbvbQuZ8h6d/abstract https://cassyni-user-files-prod.s3.amazonaws.com/AQ6morkqm9GhkRMUhoCoSe https://cassyni.com/events/QBX53oDvaAShoM7qjADQi9/seminar/qa https://cassyni.com/slides/outline/QBX53oDvaAShoM7qjADQi9 https://cassyni.com/events/QBX53oDvaAShoM7qjADQi9/abstract https://cassyni-user-files-prod.s3.amazonaws.com/GBcd6s4pCdczywcHqaykKp https://cassyni.com/events/QBX53oDvaAShoM7qjADQi9?videoPreview=1 Implementing CKD re-call at PCN levelnohttps://cassyni.com/events/QBX53oDvaAShoM7qjADQi9?videoPreview=12024-10-08T10:20:00+00:002063.2North West London Kidney Care Image credit: [National Cancer Institute (Unsplash)](https://unsplash.com/photos/womens-red-button-up-collared-long-sleeved-shirt-NNpo-liY5aU). Image credit: [Mufid Majnun (Unsplash)](https://unsplash.com/photos/a-doctor-examining-a-patient-20Y6Ib1KCXM). Image credit: [Amy Hirschi (Unsplash)](https://unsplash.com/photos/two-women-sitting-on-leather-chairs-in-front-of-table-K0c8ko3e6AA). Image credit: [Mimi Thian (Unsplash)](https://unsplash.com/photos/woman-sitting-on-yellow-armless-chair-near-gray-laptop-computer-lp1AKIUV3yo). Image credit: [National Cancer Institute (Unsplash)](https://unsplash.com/photos/man-in-white-dress-shirt-holding-white-box-byGTytEGjBo).https://cassyni-user-files-prod.s3.amazonaws.com/GBcd6s4pCdczywcHqaykKp https://cassyni.com/slides/outline/8NpyoBYuLEaHmUTLKJd7HP https://cassyni.com/events/8NpyoBYuLEaHmUTLKJd7HP/abstract https://cassyni-user-files-prod.s3.amazonaws.com/4wcZquWH7YAASZ8cNaSCWi https://cassyni.com/events/8NpyoBYuLEaHmUTLKJd7HP?videoPreview=1 Community-Centered Strategies to Reduce Gun Violence: Developing Evidence for Policy and Practicenohttps://cassyni.com/events/8NpyoBYuLEaHmUTLKJd7HP?videoPreview=12024-12-06T12:00:00+00:003574.04Sage PublishingCommunity violence interventions (CVI) typically rely on individual-level behavioral change mechanisms, including law enforcement, social services, and therapeutic treatments. A few CVI models, however, include strategies derived from a public health framework to intervene at the level of neighborhoods and communities (e.g., Cure Violence). Community-centered and community-resourced approaches are important and potentially cost-effective, but they confront numerous challenges. Measuring community-level effects can be statistically complex, and advocates who support CVI as a social reform movement sometimes disparage the search for rigorous evidence. Funding agencies may support community action regardless of the evidence. These factors, and others, have resulted in a smaller-than-expected base of research evidence about community-centered and community-resourced violence prevention approaches. This Special Collection addresses challenges involved in developing evidence-backed, community-centered CVI models. What are the conceptual origins and theoretical foundations of community-centered violence prevention strategies? What CVI strategies should or should not be considered community-centered? What evaluation evidence exists for such models? What can researchers do to strengthen the evidentiary nexus of research, policy, and practice to support the political viability and growth of community-centered and community-resourced CVI approaches?https://cassyni-user-files-prod.s3.amazonaws.com/4wcZquWH7YAASZ8cNaSCWi https://cassyni.com/slides/outline/GmuVp4abbjqmtyxpsPin3o https://cassyni.com/events/GmuVp4abbjqmtyxpsPin3o/abstract https://cassyni-user-files-prod.s3.amazonaws.com/DFH2L6BLC3EQvCzNhijNDL https://cassyni.com/events/GmuVp4abbjqmtyxpsPin3o?videoPreview=1 Novel Microorganisms Contribute to Biosulfidogenesis in the Deep Layer of an Acidic Pit Lakenohttps://cassyni.com/events/GmuVp4abbjqmtyxpsPin3o?videoPreview=12025-03-18T12:30:00+00:00503.96Microbiome Virtual International ForumCueva de la Mora is a permanently stratified acidic pit lake with extremely high concentrations of heavy metals at depth. In order to evaluate the potential for in situ sulfide production, we characterized the microbial community in the deep layer using metagenomics and metatranscriptomics. We retrieved 18 high quality metagenome-assembled genomes (MAGs) representing the most abundant populations. None of the MAGs were closely related to either cultured or non-cultured organisms from the Genome Taxonomy or NCBI databases (none with average nucleotide identity >95%). Despite oxygen concentrations that are consistently below detection in the deep layer, some archaeal and bacterial MAGs mapped transcripts of genes for sulfide oxidation coupled with oxygen reduction. Among these microaerophilic sulfide oxidizers, mixotrophic Thermoplasmatales archaea were the most numerous and represented 24% of the total community. Populations associated with the highest predicted in situ activity for sulfate reduction were affiliated with Actinobacteria, Chloroflexi, and Nitrospirae phyla, and together represented about 9% of the total community. These MAGs, in addition to a less abundant Proteobacteria MAG in the genus Desulfomonile, contained transcripts of genes in the Wood-Ljungdahl pathway. All MAGs had significant genetic potential for organic carbon oxidation. Our results indicate that novel acidophiles are contributing to biosulfidogenesis in the deep layer of Cueva de la Mora, and that in situ sulfide production is limited by organic carbon availability and sulfur oxidation.https://cassyni-user-files-prod.s3.amazonaws.com/DFH2L6BLC3EQvCzNhijNDL