CFD for Personalised vascular interventions – short-term solutions vs long term predictions

Vanessa is interested in patient-specific modelling and the development of multi-scale, multi-physics and biologically-oriented models in the cardiovascular field, in order to understand health and disease for individual patients. Vanessa’s approach uses a combination of ICT tools, systems biology approaches and biomechanics (CFD, structural mechanics & FSI). She is interested in inflammation and chronic conditions (atherosclerosis, neo-intimal hyperplasia, in-stent restenosis, etc.) but also, in the utilisation of computational tools for the design and optimisation of cardiovascular devices (mechanical heart valves, stents, LVADs). Vanessa is also interested in exploring the use of sensitivity, robustness, uncertainty and optimisation techniques/tools applied to the modelling and simulation of the cardiovascular system in order to better understand how to translate computational models into the clinic and to produce solid and valid models, to test biological hypotheses. Vanessa leads the group ”MUSE” (Multiscale Cardiovascular Engineering), the only group in UCL devoted to tackle the integration of data and information through models, at multiple length and time scales.