The Microbe's Master Plan to Control Sperm and Shape Generations - presented by Dr. Seth Bordenstein PhD

The Microbe's Master Plan to Control Sperm and Shape Generations

Dr. Seth Bordenstein PhD

Dr. Seth Bordenstein PhD
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The Microbe's Master Plan to Control Sperm and Shape Generations
Dr. Seth Bordenstein PhD
Seth Bordenstein
Pennsylvania State University

Associated Science article

R. Kaur et al. (2024) Prophage proteins alter long noncoding RNA and DNA of developing sperm to induce a paternal-effect lethality. Science
Article of record

Half of all animal species harbor bacteria and phages in the reproductive tissues, yet the extent to which these microbes influence host biology is often overlooked relative to the microbiomes of guts and roots, for instance. In this talk, I will illuminate (i) the most widespread bacterial symbiosis in the animal kingdom (Wolbachia reproductive symbionts and their phage WO) and (ii) the central dogma underpinnings by which they determine the fate of Drosophila sperm biology to create a symbiosis that is fundamental to host evolution and vector control.

References
  • 1.
    R. Kaur et al. (2024) Prophage proteins alter long noncoding RNA and DNA of developing sperm to induce a paternal-effect lethality. Science
  • 2.
    D. P. LePage et al. (2017) Prophage WO genes recapitulate and enhance Wolbachia-induced cytoplasmic incompatibility. Nature
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MVIF 33 - with Keynote talk by Prof. Seth Bordenstein
Microbiome Virtual International Forum
Cite as
S. Bordenstein (2024, November 12, MVIF 33 - with Keynote talk by Prof. Seth Bordenstein), The Microbe's Master Plan to Control Sperm and Shape Generations
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Video length 31:05
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