Even when focusing on women and gender-expansive populations, many groups remain underrepresented in medical and scientific research. As a result, examining trends in women’s healthcare often unearths the vastly different experiences of individuals with minoritized identities. Highlighting issues facing vulnerable groups is a necessary first step toward addressing the systemic issues women and gender-expansive people from all walks of life face when seeking and receiving healthcare. This special collection aims to advance scholarship at the intersection of women’s health and diversity, equity, and inclusion (DEI). We aim to illuminate how diverse experiences and systemic inequities shape health outcomes, access to care, and overall well-being for women and gender-expansive groups across various populations. Our goal is to contribute to a more comprehensive understanding of the full spectrum of issues which influence women's health and to foster dialogue that supports more equitable and inclusive healthcare practices.