Roundtable on Black in cancer research and oncology - presented by Dr. Brandon Blue MD and Dr. Kilan Ashad-Bishop and Drs. Onyinye and Folu Balogun and Runcie C.W. Chidebe Dip., BSc., MSc., and Kathryn Mcginnis and Dr Paraskevi Mallini and Dr. Lisa Hoffmann-Haas

Roundtable on Black in cancer research and oncology

Brandon Blue, Kilan Ashad-Bishop, Onyinye and Folu Balogun and Runcie C.W. Chidebe

Dr. Brandon Blue MDDr. Kilan Ashad-BishopDrs. Onyinye and Folu BalogunRuncie C.W. Chidebe Dip., BSc., MSc.,
Slide at 05:05
T cell activation requires 2 signals
Dr. Brandon Blue
MHC-Ag
CD28
T cell
Signal 1
Signal 2
Activation
Co-stimulation
IL-2 production
Cytoskeletal reorganization
Sadelain et al. Nat Rev Cancer 2003
1
References
  • 1.
    M. Sadelain et al. (2003) Targeting tumours with genetically enhanced T lymphocytes. Nature Reviews Cancer
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Summary (AI generated)

In this particular case, we are utilizing the same mechanism but with a different approach when it comes to cancer. It is important to understand that the co-stimulatory domain has shown promising outcomes across various types of cancer.