Base-Metal Catalysis - presented by Prof. Lingling Chu and Assoc. Prof. Ming Joo Koh and Prof. Zhan Lu and Assoc. Prof. Tatsuhiko Yoshino and Prof. Naohiko Yoshikai

Base-Metal Catalysis

Lingling Chu, Ming Joo Koh, Zhan Lu and Tatsuhiko Yoshino

Prof. Lingling ChuAssoc. Prof. Ming Joo KohAssoc. Prof. Tatsuhiko YoshinoProf. Zhan Lu
Slide at 1:09:26
Selective carbofunctionalization of alkenes by NHC-Ni catalysis Catalyst-controlled blueprint to generate diverse organic scaffolds Heck reaction/isomerization Dicarbofunctionalization Me Me HN-SO2 MeO2C (glycine transporter 1 inhibitor) (retinoid precursor) Hydrocarbofunctionalization [Ni] Enantioselective synthesis NHC-Ni catalyst Ar1=4-OMe-CgH4 (N1L protein antagonist) (narcotic agonists)
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Summary (AI generated)

Summary: In addition to utilizing Nickel chemistry, we also focus on iron chemistry for Multicomponent cross coupling reactions. This allows us to create valuable compounds, including bioactive molecules, as outlined on the Slide.