Base-Metal Catalysis - presented by Prof. Lingling Chu and Assoc. Prof. Ming Joo Koh and Prof. Zhan Lu and Assoc. Prof. Tatsuhiko Yoshino and Prof. Naohiko Yoshikai

Base-Metal Catalysis

Lingling Chu, Ming Joo Koh, Zhan Lu and Tatsuhiko Yoshino

Prof. Lingling ChuAssoc. Prof. Ming Joo KohAssoc. Prof. Tatsuhiko YoshinoProf. Zhan Lu
Slide at 1:09:48
Me Me
Me Me
urokinase receptor ligand
HN-SO2
MeO2C
retinoid precursor
glycine transporter 1 inhibitor
G2-X
Base metal catalysis
R1-N
G2-Y
B(pin)
narcotic agonists
Chem 2020, 6, 738.
Nat. Ca
lat. Catal 2020, 3, 585.
Ar' = 4-OMe-CgH4
(pin)B
Nat Che
Commun 2020, 11,5857.
kinase inhibitor precursor
ACS Cat
N1L protein antagonist
ACS, 2020, 142, 21410.
Chem Ca
ACIE, 2021, 60, 2104.
ACIE, 2022
ACS, 2021, 143, 9498
(+)-Imperanene
Nat. Cat
Chem 2021, 7, 993.
Nat. Cata
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References
  • 1.
    T. Yang et al. (2020) Broadly Applicable Directed Catalytic Reductive Difunctionalization of Alkenyl Carbonyl Compounds. Chem
  • 2.
    X. Yu et al. (2020) Site-selective alkene borylation enabled by synergistic hydrometallation and borometallation. Nature Catalysis
  • 3.
    X. Chen et al. (2020) Alkyl halides as both hydride and alkyl sources in catalytic regioselective reductive olefin hydroalkylation. Nature Communications
  • 4.
    T. Yang et al. (2020) Chemoselective Union of Olefins, Organohalides, and Redox-Active Esters Enables Regioselective Alkene Dialkylation. Journal of the American Chemical Society
  • 5.
    X. Yu et al. (2020) Iron‐Catalyzed Regioselective Alkenylboration of Olefins. Angewandte Chemie International Edition
  • 6.
    C. Liu et al. (2021) Catalytic Regioselective Olefin Hydroarylation(alkenylation) by Sequential Carbonickelation-Hydride Transfer. Journal of the American Chemical Society
  • 7.
    Y. Jiang et al. (2021) Nickel-catalyzed site- and stereoselective reductive alkylalkynylation of alkynes. Chem
  • 8.
    C. Liu et al. (2021) Olefin functionalization/isomerization enables stereoselective alkene synthesis. Nature Catalysis
  • 9.
    H. Wang et al. (2021) Directing-group-free catalytic dicarbofunctionalization of unactivated alkenes. Nature Chemistry
  • 10.
    H. Wang et al. (2021) N-Heterocyclic Carbene–Nickel-Catalyzed Regioselective Diarylation of Aliphatic-1,3-Dienes. ACS Catalysis
  • 11.
    T. Senthamarai et al. (2021) A “universal” catalyst for aerobic oxidations to synthesize (hetero)aromatic aldehydes, ketones, esters, acids, nitriles, and amides. Chem
  • 12.
    Y. Zhao et al. (2022) Stereoselective Synthesis of Trisubstituted Alkenes by Nickel‐Catalyzed Benzylation and Alkene Isomerization. Angewandte Chemie International Edition
  • 13.
    C. Liu et al. (2022) Synthesis of tri- and tetrasubstituted stereocentres by nickel-catalysed enantioselective olefin cross-couplings. Nature Catalysis
  • 14.
    Z. Wang et al. (2023) Enantioselective C–C cross-coupling of unactivated alkenes. Nature Catalysis
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Summary (AI generated)

Before I end my talk, I want to acknowledge the hard work done by my students, postdocs, and collaborators, both past and present. We have worked together on understanding our reactions, and I want to thank the funding support from Singapore and other monetary awards from different agencies. Thank you.