The human virome in health and disease - presented by Prof. Frederic Bushman

The human virome in health and disease

Prof. Frederic Bushman

Prof. Frederic Bushman
Slide at 12:11
Assessing phage production from 24 bacterial isolates Aerobic Anaerobic Citrobacter Enterobacter Enterococcus More than 80% strains produced substantial level of Escherichia VLPs Klebsiella Pseudomonas inducer article number per ml media Month 0 Month 1 Month 4 0 102 10 4 10 6 10 8 10 10 studio.streamyard.com is sharing your screen Stop sharing Hide
Share slide
Summary (AI generated)

We took 24 strains from the babies and tested if they were producing phage. Each row represents one of the 24 strains, with columns showing the conditions used for induction - either with an inducer (mitomycin C) or without, and under aerobic or anaerobic conditions. The number of particles produced is displayed in the table.

It was observed that over half of the strains produced phage, especially in the presence of DNA damage. In fact, 80% of the strains produced significant levels of virus-like particles. This suggests that a large amount of virus is being produced when induced in the presence of DNA damage.