The human virome in health and disease - presented by Prof. Frederic Bushman

The human virome in health and disease

Prof. Frederic Bushman

Prof. Frederic Bushman
Slide at 11:54
Computational classification of the phage lifestyle
Cross-assembly over three time
points within each subject
More than 50% of ORFs within a
contig to be annotated as viral
Phage Classification Tool Set (PHACTS) algorithm
0.75
0.75
Lytic
Probability
Temperate
Infant stool viral contigs more closely resembled temperate
phage than Ivtic phage
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Summary (AI generated)

A computational classification of the phage lifestyle using PHACST suggested that phages tend to be more temperate than lytic. This points towards temperate life cycle-induced prophages rather than lytic growth.