The human virome in health and disease - presented by Prof. Frederic Bushman

The human virome in health and disease

Prof. Frederic Bushman

Prof. Frederic Bushman
Slide at 09:05
Quantifying bacterial colonization using 16S rRNA gene qPCR
10 12
P = 0.0003
P<0.0001
Bacterial 16S rRNA gene copies were
low or undetectable in month 0 samples
Percentage of human DNA in samples
falls significantly with time after birth as
bacterial DNA increases.
Implication: most babies are usually
sterile at birth, and become colonized
after rupture of membranes and
delivery
Month
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Summary (AI generated)

Most babies do not have much 16S rRNA present at birth. Colonization typically occurs soon after birth. This data, along with other information, suggests that the womb is usually sterile when a baby is born and colonization happens quickly.