Base-Metal Catalysis - presented by Prof. Lingling Chu and Assoc. Prof. Ming Joo Koh and Prof. Zhan Lu and Assoc. Prof. Tatsuhiko Yoshino and Prof. Naohiko Yoshikai

Base-Metal Catalysis

Lingling Chu, Ming Joo Koh, Zhan Lu and Tatsuhiko Yoshino

Prof. Lingling ChuAssoc. Prof. Ming Joo KohAssoc. Prof. Tatsuhiko YoshinoProf. Zhan Lu
Slide at 1:39:26
Further Optimization Co catalyst NHCOPh (5 mol %) H2-BHTL (10 mol %) Me Bn solvent, 40 °C, 24 h [Cp*Co(CH3CN)3](SbF6)2 [Cp*iBuCo(CH3CN)3](SbF6)2 [SbF6]2 [SbF6]2 in DCE in DCE 93%, 87:13 er 30%, 90:10 er in DCE + MS13X 68%, 90:10 er in o-CI2C6H4 + MS13X 81%, 92:8 er
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Summary (AI generated)

We chose the reaction conditions based on improving reactivity and achieving an acceptable yield. The solvent was selected to enhance the reaction and angios activity. There is room for improvement in terms of selectivity. The molecular series showed compatibility with various α V and α A groups. However, reactivity and selectivity slightly dropped and we may need to consider changing the Dixon.