Real-time multicompartment Hodgkin-Huxley neuron emulation on SoC FPGA - presented by Pr Timothée Levi

Real-time multicompartment Hodgkin-Huxley neuron emulation on SoC FPGA

Pr Timothée Levi

Pr Timothée Levi
Slide at 24:03
Timothee
Biomimetic options
100 ms
100 ms
FS Neuron
RS Neuron
AMPA synapse
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500 mV/div
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Summary (AI generated)

We can see the raster plot displaying the membrane potential for each neuron in real time. Our collaboration with Universaly, experts in the organoid model, involved the development of three types of organoids from human IP cells. These include single organoids, assembloids where two organoids are placed close together to form connections, and connectoids where two organoids are placed at a distance and connected through microfluidic channels. Our model of these organoids was compared to biological recordings, resulting in a publication in Nature Communications. The single organoid model showed more connectivity at the surface, while the connectoid model showed more synaptic activity and connectivity at the external part due to the formation of axon bundles through microfluidic channels.