Roundtable on Black in cancer research and oncology - presented by Dr. Brandon Blue MD and Dr. Kilan Ashad-Bishop and Drs. Onyinye and Folu Balogun and Runcie C.W. Chidebe Dip., BSc., MSc., and Kathryn Mcginnis and Dr Paraskevi Mallini and Dr. Lisa Hoffmann-Haas

Roundtable on Black in cancer research and oncology

Brandon Blue, Kilan Ashad-Bishop, Onyinye and Folu Balogun and Runcie C.W. Chidebe

Dr. Brandon Blue MDDr. Kilan Ashad-BishopDrs. Onyinye and Folu BalogunRuncie C.W. Chidebe Dip., BSc., MSc.,
Slide at 24:30
LACK OF DIVERSITY IN GENOMIC DATABASES & STUDIES The Onc Docs Dr. On. Percent Representation of Racial and Ethnic FIGURE 1 Minorities in the U.S. Population The major population groups 61.6% are shown as percent of the U.S Non-Hispanic White population based on the U.S. Census Hispanic/Latino(a) 2020. Numbers represent percent B/AA of the U.S. population: non-Hispanic Asian White, 61.6; Hispanic or Latino, 18.7; AI/AN Black or African American (B/AA)b, NHOPI 12.4; Asianb, 6.0; American Indian or 18.7% Alaska Native (AI/AN)b, 1.1; and Native 12.4% Hawaiian or Other Pacific Islander (NHOPI)b, 0.2. 6.0% 1.1% 0.2% . Hispanic people may be of any race. so are also included in applicable race categories MAJOR U.S. POPULATION GROUPS b Includes persons reporting only one race. American Association for Cancer Research (AACR) Cancer Disparities Progress Report 2022 Weill Cornell Medicine NewYork-Presbyterian
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References
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    https://cancerprogressreport.aacr.org/disparities/
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Summary (AI generated)

And so, that just basically reflects who we enroll in clinical trials. I'm sure many of you have heard the conversations about the lack of representation from different minority backgrounds in clinical trials. This issue also affects the genomic studies we conduct to understand cancer, as we don't enroll enough individuals.

For instance, with the TCGA, it is evident that over 75% of their participants are of European ancestry. This trend is similarly observed with the Project genie. However, it is crucial to enroll individuals from diverse backgrounds because there are clear differences that need to be accounted for.