Precision Microbiome Health Care

The human microbiome is a high dimensional and dynamic part of our physiology that plays a key role in managing health and individualized responses to diet and medicine. The immune system controls our interaction with the microbial world, and the microbial communities in our bodies are central to modulating the immune response. Changes in the human microbiome and their metabolism have substantial influence on atopy, neurological disorders, metabolic disorders, and a range of complex conditions and disease states. Diet is incredibly important in shaping human health and the microbiome, altering both composition and metabolic activity, resulting in changes in immune, endocrine, and neurological systems. Measuring diet through surveys, apps, or photographs has become indispensable to our efforts to associate microbiome composition with physiological response to specific dietary components. Microbiome-Wide Association Studies (MWAS) combined with novel quantitative multi-omic approaches and automated at-home sampling devices are enabling us to use AI techniques to determine personalized responses to nutrition that drive diseases states and treatment efficacy. Through these innovations we are finally realizing the paradigm of precision medicine for facilitating patient care.